Claudia Paz Saavedra Sánchez
Full Professor
UNIVERSIDAD ANDRÉS BELLO
Santiago, Chile
Structural and functional studies of Salmonella Typhimurium Porins; Structural and biochemical studies of enzymes; Molecular resistance strategies to adverse conditions present in extreme environments
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Biochemistry, UNIVERSIDAD DE CHILE. Chile, 2002
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Biochemist, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 1989
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Masters in Biological Sciences with mention in Molecular and Cellular Biology, UNIVERSIDAD DE CHILE. Chile, 1997
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Post-PhD Research, TEXAS A&M UNIVERSITY. Estados Unidos, 2003
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Postdoctoral student Full Time
TEXAS A&M UNIVERSITY
Biology
College Station, Texas, Estados Unidos
2002 - 2003
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Assistant professor Part Time
UNIVERSIDAD DE SANTIAGO DE CHILE
Faculty of chemistry and biology
Santiago, Chile
1995 - 2003
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assistant professor Full Time
UNIVERSIDAD ANDRES BELLO
Faculty of Biological Sciences
Santiago, Chile
2005 - 2014
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Full professor Full Time
UNIVERSIDAD ANDRES BELLO
Santiago, Chile
2015 - At present
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Assistant professor Full Time
Universidad de Talca
Talca, Chile
1989 - 1995
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Associate professor Part Time
Universidad de Santiago
Santiago, Chile
1995 - 2004
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Biochemistry School Director Full Time
Universidad Andrés Bello
Santiago, Chile
2005 - At present
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Academic microbiology area Part Time
Inacap
Santiago, Chile
1995 - 2004
Fernando Olate; U. Chile / UNAB-Biochemistry; Sponsor; 2009.
Andrea Lorenzi; U. Chile / UNAB-Biochemistry; Sponsor; 2009.
Patricia Muñoz; U. Chile / UNAB-Biochemistry; Sponsor; 2009.
Miriam Barros; U. Chile / UNAB-Biochemistry; Sponsor; 2009.
Nataly Contreras; U. Chile / UNAB-Biochemistry; Sponsor; 2009.
Carolina Leal; U. Chile / UNAB-Biochemistry; Sponsor; 2009.
Mauricio Valdivia; USACH / UNAB-Biochemistry; Sponsor; 2010.
Juan Pablo Monras; USACH / UNAB-Biochemistry; Sponsor; 2010.
Cristian Sabotier; USACH / UNAB-Biochemistry; Sponsor; 2010.
Catalina Chahuán; UNAB / Biochemistry – Master in Biochemistry; Tutor of Undergraduate Research Unit; 2008-2009.
Debbie Monsalva; UNAB / Biochemistry – Master in Biochemistry; Tutor of Undergraduate Research Unit; 2010.
Samuel Parra; UNAB / Biochemistry – Master in Biochemistry; Tutor of Undergraduate Research Unit; 2009-2010.
Patricio Guerrero; UNAB / Biochemistry – Master in Biochemistry; Tutor of Undergraduate Research Unit; 2010-2011.
Carolina Cabezas; UNAB / Biochemistry – Master in Biochemistry; Tutor of Undergraduate Research Unit; 2012.
Paulina Calderón; UNAB / Biochemistry – Master in Biochemistry; Tutor of Undergraduate Research Unit; 2012.
Ricardo Álvarez; UNAB / Biochemistry – Master in Biochemistry; Tutor of Undergraduate Research Unit; 2012.
Roberto Luraschi; UNAB / Biochemistry – Master in Biochemistry; Tutor of Undergraduate Research Unit; 2013.
Alan Briones; UNAB / Biochemistry – Master in Biochemistry; Tutor of Undergraduate Research Unit; 2013-2014.
Ana Inostroza; UNAB / Biochemistry – Master in Biochemistry; Tutor of Undergraduate Research Unit; 2013-2014.
Sylvana Urra; UNAB / Biochemistry – Master in Biochemistry; Tutor of Undergraduate Research Unit; 2013-2014.
Cesar Salinas; UNAB / Biochemistry – Master in Biochemistry; Tutor of Undergraduate Research Unit; 2015-2016.
María Graciela Delgado; Master in Biochemistry/UNAB; Masters thesis tutor; 2009.
Juan Ignacio Gutiérrez; Master in Biochemistry/UNAB; Masters thesis tutor; 2009.
Nelson Caro; Master in Biochemistry/UNAB; Masters thesis tutor; 2009.
Bernardo Collao; Master in Biochemistry/UNAB; Masters thesis tutor; 2010.
Catalina Chahuán; Master in Biochemistry/UNAB; Masters thesis tutor; 2010.
Samuel Parra; Master in Biochemistry/UNAB; Masters thesis tutor; 2011.
Nicolás Pacheco; Master in Biochemistry/UNAB; Masters thesis tutor; 2012.
Debbie Monsalva; Master in Biochemistry/UNAB; Masters thesis tutor; 2012.
Marlen Espinoza; Master in Biochemistry/UNAB; Masters thesis tutor; 2013-2014.
Roberto Luraschi; Master in Biochemistry/UNAB; Masters thesis tutor; 2013-2014.
Carolina Cabezas; Master in Biochemistry/UNAB; Masters thesis tutor; 2014.
Alan Briones; Master in Biochemistry/UNAB; Masters thesis tutor; 2014.
Ana Inostroza; Master in Biochemistry/UNAB; Masters thesis tutor; 2014.
Sylvana Urra; Master in Biochemistry/UNAB; Masters thesis tutor; 2014.
Cesar Salinas; Master in Biochemistry/UNAB; Masters thesis tutor; 2016.
Camila Aguirre; Master in Biochemistry/UNAB; Masters thesis tutor; 2017.
Fernando Gil Michell; Molecular Biosciences PhD program/UNAB; Thesis tutor; 2010.
José Miguel Villarreal; Biotechnology PhD program/UNAB; Thesis tutor; 2010.
Francisco Ipinza; Biotechnology PhD program/UNAB; Thesis tutor; 2012.
Eduardo Morales; Molecular Biosciences PhD program/UNAB; Thesis tutor; 2013
Bernardo Collao; Molecular Biosciences PhD program/UNAB; Thesis tutor; 2014.
Mario Navarrete; Molecular Biosciences PhD program/UNAB; Member of the evaluation committee preliminary draft thesis ; 2010.
Matías Jofre; Molecular Biosciences PhD program/UNAB; Member of the evaluation committee preliminary draft thesis ; 2011.
Cristóbal Mujica; Biotechnology PhD program/UNAB; Member of the evaluation committee preliminary draft thesis ; 2011.
Annettte Nicole Trombert; Molecular Biosciences PhD program/UNAB; Member of the evaluation committee preliminary draft thesis ; 2011.
Hugo González; Molecular Biosciences PhD program/UNAB; Member of the evaluation committee preliminary draft thesis ; 2011.
Héctor Osorio; Molecular Biosciences PhD program/UNAB; Member of the evaluation committee preliminary draft thesis ; 2012.
Daniela Doñas; Molecular Biosciences PhD program/UNAB; Member of the evaluation committee preliminary draft thesis ; 2012.
Nicolás Villagra; Molecular Biosciences PhD program/UNAB; Member of the evaluation committee preliminary draft thesis ; 2012.
María Graciela Delgado; Master in Biochemistry/UNAB; President of examination committee degree; 2009.
Juan Ignacio Gutiérrez; Master in Biochemistry/UNAB; President of examination committee degree; 2009.
Simón Vidal; Master in Biochemistry/UNAB; Degree examination committee member; 2009.
Bernardo Collao; Master in Biochemistry/UNAB; President of examination committee degree; 2009.
Carlos Rosales; Master in Biochemistry/UNAB; Degree examination committee member; 2009.
Cristobal Mujica; Molecular Biosciences PhD program/UNAB; President qualifying examination committee; 2009.
Héctor Osorio; Molecular Biosciences PhD program/UNAB; Qualifying examination committee member; 2010.
Matias Jofré; Molecular Biosciences PhD program/UNAB; Qualifying examination committee member; 2010.
Annette Nicole Trombert; Molecular Biosciences PhD program/UNAB; Qualifying examination committee member; 2011.
Daniela Doñas; Molecular Biosciences PhD program/UNAB; Qualifying examination committee member; 2013.
César Echeverría; Molecular Biosciences PhD program/UNAB; Qualifying examination committee member; 2013.
Nicolás Villagra; Molecular Biosciences PhD program/UNAB; Qualifying examination committee member; 2014.
Bernardo Collao; Molecular Biosciences PhD program/UNAB; Research unit Tutor; 2010.
Eduardo Morales; Molecular Biosciences PhD program/UNAB; Research unit Tutor; 2010.
Actividades de Difusion
2020
Nombre Actividad realizada N° estudiantes DBCM participantes (1) N° académicos participantes (2) N° total de asistentes inlcyendo (1) y (2) Web page o link de la evidecia de la actividad (o adjuntar imagen en el email)
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Nota 0 1 1 https://www.biobiochile.cl/noticias/nacional/chile/2020/09/28/expertos-sugieren-que-baja-de-casos-activos-es-efecto-del-rezago-de-fiestas-patrias.shtml
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Entrevista 0 1 1 Claudia Saavedra, académica de la Unab
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Nota 0 1 1 https://www.biobiochile.cl/noticias/nacional/chile/2020/12/06/el-calor-y-la-transmision-aerea-de-la-covid-19-como-ventilar-los-espacios-cerrados-este-verano.shtml
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Entrevista 0 1 1 Influyentes: Entrevista a Claudia Saavedra, pdta SOMICH y académica UNAB.
Permeability and localization of nitroxide pre-fluorescent probes in epithelial cells |
Fusion of neural gas |
Comparison of molecular regulation strategies for two bacterial lifestyle models in response to niche oxidative stress challenges |
Evaluación de mecanismos de resistencia presentes en microorganismos que prosperan en ambientes naturales con arsénico=> caso del género Exiguobacterium en el Salar de Huasco. |
Evaluación de mecanismos de resistencia presentes en microorganismos que prosperan en ambientes naturales con arsénico=> caso del género Exiguobacterium en el Salar de Huasco. |
Identification and characterization of non-cognate partners of the Salmonella Typhimurium ArcAB two-component system in response to hydrogen peroxide and hypochlorous acid |
Identification and characterization of non-cognate partners of the Salmonella Typhimurium ArcAB two-component system in response to hydrogen peroxide and hypochlorous acid. |
Clarify the role of the two-ArcAB components in response to NaOCl |
ROLE OF THE SALMONELLA TYPHIMURIUM CYSJIH OPERON AND CYSTEINE DESULFHYDRASE METC IN THE RESPONSE TO BACTERICIDAL ANTIBIOTIC-DERIVED ROS=> HYDROGEN SULFIDE ACCUMULATION AS A MECHANISM OF RESISTANCE |
ArcA and SlyA-mediated response to radical oxygen species in Salmonella. |
ARCA AND SLYA-MEDIATED RESPONSE TO RADICAL OXYGEN SPECIES IN SALMONELLA |
IDENTIFICATION AND ANALYSIS OF PSEUDOGENES INVOLVED IN THE EVOLUTIONARY ADAPTATION OF SALMONELLA TYPHI TO THE HUMAN HOST |
Identification and analysis of pseudogenes involves in the evolutionary adaptation of Salmonella Typhi to the humnan host. |
Down-regulation of the porins expresión in Salmonella enterica serovar Typhimurium on oxidative. |
Participación de las porinas de Salmonella enterica serovar Typhimurium en la expulsión de moléculas derivadas del estrés oxidativo. |
LAS PORINAS OMPW, OMPD Y OMPL DE SALMONELLA ENTERICA SEROVAR TYPHIMURIUM CONTRIBUYEN A LA HOMEOSTASIS DEL PERIPLASMA Y A LA SUPERVIVENCIA DE LA BACTERIA EN EL HOSPEDERO. |
Nitroxides prefluorescent probles on the free radical monitoring in proteins, monolayers and cells. |
Caracterización bioquímica de las proteínas de membrana externa, OmpD y OmpW de Salmonella enterica serovar Typhimurium. |
SALMONELLA ENTERICA SEROVAR Typhi, PATOGENO ESPECIFICO Y CRONICO DEL SER HUMANO=> CARACTERIZACION DE MECANISMOS MOLECULARES DE SU PATOGENICIDAD. |
Salmonella enterica serovar Typhi, patógeno específico y cróncio del ser humano=> caracterización de mecanismos moleculares de su patogenecidad. |
La proteína OmpW de Salmonella enterica serovar Typhimurium, participa en la expulsión de metil viológeno desde la célula. |
PARTICIPACION DE LAS PROTEINAS DE MEMBRANA EXTERNA OMPD Y OMPW DE SALMONELLA ENTERICA SEROVAR TYPHIMURIUM EN LA EXPULSION DE SUSTANCIAS TOXICAS DESDE LA CELULA |
Participación de las proteínas de membrana externa OmpD y OmpW de Salmonella enterica serovar Typhimurium en la expulsión de sustancias tóxicas desde la célula. |
REACCIONES DE TRANSFERENCIA DE HIDROGENO DESDE ANTIOXIDANTES A RADICALES NITROXIDO EN SISTEMAS DE INTERES BIOLOGICO. |
Reacciones de transferencia de hidrógeno desde antioxidantes a radicales nitróxido en sistemas de interés biológico. |
RESISTENCIA BACTERIANA A TELURITO DE POTASIO=> ESTUDIO DE LA PARTICIPACION DE GENES DEL METABOLISMO DE LA CISTEINA DE BACILLUS STEAROTHERMOPHILUS V. |
Resistencia bacteriana a telurito de potasio=> estudio de la participación de genes del metabolismo de la cisteína de Bacillus stearothermophilus V. |
Estudios estructurales de la cisteína sintetasa de Bacillus stearothermophilus V=> Participación del extremo carboxilo terminal en la funcionalidad de la enzima. |
Estudio sobre las bases moleculares de la resistencia a telurito de potasio en Bacillus stearothermophilus V. |
ESTUDIO SOBRE LAS BASES MOLECULARES DE LA RESISTENCIA A TELURITO DE POTASIO EN BACILLUS STEAROTHERMOPHILUS V. |
Estudios moleculares sobre la resistencia a telurito de potasio en Bacillus stearothermophilus V. |
IDENTIFICACION Y ANALISIS DE DOMINIOS FUNCIONALES EN LAS ENZIMAS DEL SISTEMA DE RESTRICCION-MODIFICACION BSTVI DE BACILLUS STEAROTHERMOPHILUS V |
Identificación y análisis de dominios funcionales en las enzimas del sistema de restricción-modificación BstVI de Bacillus stearothermophilus V. |
Localización de sitios funcionales en la endonucleasa de restricción BstVI. |
AUTORESTRICCION DEL DNA CROMOSOMAL EN BACTERIAS=> ESTUDIOS DE LOS MECANISMOS DEL PROTECCION ADICIONAL A LA MODIFICACION DEL DNA POR METILACION |
Autorestricción del DNA cromosomal en bacterias=> estudios de los mecanismos de protección adicionales a la modificación del DNA por metilación. |
REGULACION DE LA EXPRESION GENICA DEL SISTEMA DE MODIFICACION RESTRICCION DE BACILUS STEAROTHERMOPHILUS Y SU RELACION CON EL PROCESO DE ESPORULACION |
Regulación de la expresión génica del sistema de modificación-restricción de Bacillus stearothermophilus V y su relación con el proceso de esporulación |
CARACTERIZACION ESTRUCTURAL Y BIOQUIMICA DEL SISTEMA DE MODIFICACION- RESTRICCION DE BACILLUS STEAROTHERMOPHILUS V. |
Caracterización estructural y bioquímica del sistema de modificación- restricción de Bacillus stearothermophilus V. |
Two-photon high-dimensional spatial entanglement: Theory and experiment |