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Guido Carlos Mora Longa

Académico/Investigador

Universidad SEK

Santiago, Chile

Molecular Biology, UNIVERSITY OF WISCONSIN-MADISON. Estados Unidos, 1971
Licenciado en Bioquímica y Bioquímico, UNIVERSIDAD DE CHILE. Chile, 1965

Director Carrera Medicina Full Time

Universidad Andres Bello

Santiago, Chile

2014 - 2019

PREMIO

ORGANIZACION PANAMERICA DE LA SALUD

Chile, 1986

Mejor trabajo científico presentado en el X Congreso de la Asociación Chilena de Microbiología,

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Inactivation of Glutamine Synthetase-Coding Gene glnA Increases Susceptibility to Quinolones Through Increasing Outer Membrane Protein F in Salmonella enterica Serovar Typhi Mora A.Y.; Saavedra, C. P.; Villagra N.A.; Mora, G. C.; Hidalgo, A. A. Article ISI SCOPUS FRONTIERS IN MICROBIOLOGY (2020)
Cysteine auxotrophy drives reduced susceptibility to quinolones and paraquat by inducing the expression of efflux-pump systems and detoxifying enzymes in S. Typhimurium Villagra NA, Valenzuela LM, Mora AY, Millanao AR, Saavedra CP, Mora GC, Hidalgo AA. Article ISI SCOPUS BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2019)
Xylose Improves Antibiotic Activity of Chloramphenicol and Tetracycline against K. pneumoniae and A. baumannii in a Murine Model of Skin Infection Hidalgo, Alejandro A.; Arias, Angel J.; Fuentes, Juan A.; Mora, Guido C. Article ISI SCOPUS CANADIAN JOURNAL OF INFECTIOUS DISEASES & MEDICAL MICROBIOLOGY (2018)
Expression of IroN, the salmochelin siderophore receptor, requires mRNA activation by RyhB small RNA homologues Balbontín R.; Villagra, N; Pardos de la Gándara M.; Mora, G; Bossi L. Article ISI SCOPUS MOLECULAR MICROBIOLOGY (2016)
Lose to win: marT pseudogenization in Salmonella enterica serovar Typhi contributed to the surV-dependent survival to H2O2, and inside human macrophage-like cells Urrutia, Ítalo M.; Talamilla-Espinoza, A. Article ISI SCOPUS INFECTION GENETICS AND EVOLUTION (2016)
SPI-9 of Salmonella enterica serovar Typhi is constituted by an operon positively regulated by RpoS and contributes to adherence to epithelial cells in culture Article ISI SCOPUS MICROBIOLOGY-SGM (2016)
Theoretical and experimental characterization of a novel pyridine benzimidazole: suitability for fluorescence staining in cells and antimicrobial properties Carreno, A.; Gacitua, M; Fuentes, J. A.; Araneda, C; Chavez, I; ManrÍquez J.M.; Polanco, R.; Mora, G. C.; Otero, C.; Swords W.B. Article ISI SCOPUS NEW JOURNAL OF CHEMISTRY (2016)
Pseudogenization of sopA and sopE2 is functionally linked and contributes to virulence of Salmonella enterica serovar Typhi Hidalgo, AA; Rodriguez, L; urrutia im; Paredes Sabja D; Gil, F; Saavedra, CP; Mora, GC; Fuentes, JA. Article ISI SCOPUS INFECTION GENETICS AND EVOLUTION (2015)
Spectral, theoretical characterization and antifungal properties of two phenol derivative Schiff bases with an intramolecular hydrogen bond Carreno, A.; Gacitua, M; Paez-Hernandez, D; Polanco, R.; Preite, M.; Fuentes, JA.; Mora, GC; Chavez, I; Arratia-Perez, R Article ISI SCOPUS New Journal of Chemistry (2015)
stg fimbrial operon from S. Typhi STH2370 contributes to association and cell disruption of epithelial and macrophage-like cells Berrocal, L; Fuentes, JA.; Trombert, AN; Jofre, MR; Mora, GC Article ISI SCOPUS Biological Research (2015)
Draft Genome Sequence of Salmonella enterica Serovar Typhi Strain STH2370 Ugalde, J. A.; Mora, G. C.; Santiviago, C. A. Article SCOPUS Genome Announcements (2014)
RpoS integrates CRP, Fis, and PhoP signaling pathways to control Salmonella Typhi hlyE expression Jofre, MR; Rodriguez, LM; Hidalgo, AA; Mora, GC; Fuentes, JA. Article ISI SCOPUS BMC MICROBIOLOGY (2014)
Salmonella Typhi shdA: Pseudogene or allelic variant? urrutia im; Fuentes, JA.; Hidalgo, AA; Mora, GC Article ISI SCOPUS INFECTION GENETICS AND EVOLUTION (2014)
Porin alterations present in non-carbapenemase-producing Enterobacteriaceae with high and intermediate levels of carbapenem resistance in Chile Wozniak A.; Villagra N.A.; Undabarrena, A.; Gallardo N.; Keller, N; Moraga M.Á.; Mora, G. C.; Garcia P. Article ISI SCOPUS Journal of Medical Microbiology (2012)
Synthesis of CdTe QDs/single-walled aluminosilicate nanotubes hybrid compound and their antimicrobial activity on bacteria Geraldo D.A.; Arancibia-Miranda, N; Villagra N.A.; Mora, G. C.; Arratia-Perez, R Article ISI SCOPUS Journal of Nanoparticle Research (2012)
The carbon source influences the efflux pump-mediated antimicrobial resistance in clinically important Gram-negative bacteria Villagra N.A.; Fuentes, J. A.; Hidalgo, A. A.; Garcia P.; Mora, G. C. Article ISI SCOPUS Journal of Antimicrobial Chemotherapy (2012)
A holin remnant protein encoded by STY1365 is involved in envelope stability of Salmonella enterica serovar Typhi Trombert, AN; Mora, GC Article ISI SCOPUS FEMS Microbiology Letters (2011)
Response regulator ArcA of Salmonella enterica serovar Typhimurium downregulates expression of OmpD, a porin facilitating uptake of hydrogen peroxide Calderon I.L.; Morales E. ; Caro N.J.; Chahuan C.A.; Collao B; Gil, F; IPINZA, F.; Mora, G. C.; Saavedra, C. P. Article ISI SCOPUS RESEARCH IN MICROBIOLOGY (2011)
Modified Intracellular-Associated Phenotypes in a Recombinant Salmonella Typhi Expressing S. Typhimurium SPI-3 Sequences Retamal P.; Castillo-Ruiz, M; Morgado, J; Mora, GC Article ISI SCOPUS PLOS ONE (2010)
S. Typhimurium sseJ gene decreases the S. Typhi cytotoxicity toward cultured epithelial cells Trombert, AN; Berrocal, L; Fuentes, JA.; Mora, GC Article ISI SCOPUS BMC Microbiology (2010)
Salmonella enterica serovar Typhi has a 4.1 kb genetic island inserted within the sapABCDF operon that causes loss of resistance to the antimicrobial peptide protamine Contreras, I; Mora, GC Article ISI SCOPUS Journal of Antimicrobial Chemotherapy (2010)
Characterization of MgtC, a Virulence Factor of Salmonella enterica Serovar Typhi Retamal P.; Castillo-Ruiz, M; Mora, GC Article ISI SCOPUS PLOS ONE (2009)
RpoS- and Crp-dependent transcriptional control of Salmonella Typhi taiA and hlyE genes: role of environmental conditions Fuentes, JA.; Jofre, MR; Mora, GC Article ISI SCOPUS RESEARCH IN MICROBIOLOGY (2009)
SmvA, and not AcrB, is the major efflux pump for acriflavine and related compounds in Salmonella enterica serovar Typhimurium Hidalgo, AA; Santiviago, CA; Saavedra, CP; Mora, GC Article ISI SCOPUS JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2008)
The capacity of Salmonella to survive inside dendritic cells and prevent antigen presentation to T cells is host specific Bueno, SM; Mora, GC; Pereda, CJ; SALAZAR ONFRAY F Article ISI SCOPUS IMMUNOLOGY (2008)
The Salmonella Typhi hlyE gene plays a role in invasion of cultured epithelial cells and its functional transfer to S. Typhimurium promotes deep organ infection in mice Fuentes, JA.; Villagra, N; Castillo-Ruiz, M; Mora, GC Article ISI SCOPUS RESEARCH IN MICROBIOLOGY (2008)
The ompW (porin) gene mediates methyl viologen (paraquat) efflux in Salmonella enterica serovar Typhimurium Gil, F; IPINZA, F.; Fuentes, J; Pumeron, P; Villarreal, JM; Aspée A.; Mora, GC; Vásquez CC; Saavedra, C. Article ISI SCOPUS RESEARCH IN MICROBIOLOGY (2007)
The cotranscribed Salmonella enterica sv. Typhi tsx and impX genes encode opposing nucleoside-specific import and export proteins Bucarey, SA; Fuentes, JA.; Mora, GC Article ISI SCOPUS GENETICS (2006)
Genetic analysis of antibiotic-resistance determinants in multidrug-resistant Shigella strains isolated from Chilean children Farfan, M; Contreras, I; Flores, O; Navarro, N; Mora, GC; PRADO, V Article ISI SCOPUS EPIDEMIOLOGY AND INFECTION (2005)
The Salmonella enterica serovar Typhi tsx gene, encoding a nucleoside-specific porin, is essential for prototrophic growth in the absence of nucleosides Bucarey, SA; Martinic, MP; Trombert, AN; Santiviago, CA; Maulen, NP; Youderian, P; Mora, GC Article ISI SCOPUS INFECTION AND IMMUNITY (2005)
Insertions of mini-Tn10 transposon T-POP in Salmonella enterica sv. typhi Hidalgo, AA; Trombert, AN; Castro-Alonso, JC; Santiviago, CA; Tesser, BR; Youderian, P; Mora, GC Article ISI SCOPUS GENETICS (2004)
Precise Excision of the Large Pathogenicity Island, SPI7, in Salmonella enterica Serovar Typhi Bueno, S. M.; Santiviago, C. A.; Murillo A.A.; Fuentes, J. A.; Trombert, A. N.; Rodas P.I.; Mora, G. C.; Youderian, P Article SCOPUS JOURNAL OF BACTERIOLOGY (2004)
Global regulation of the Salmonella enterica serovar Typhimurium major porin, OmpD Santiviago, CA; Hidalgo, AA; Youderian, P; Mora, GC Article ISI SCOPUS JOURNAL OF BACTERIOLOGY (2003)
Prophage contribution to bacterial population dynamics Bossi L.; Fuentes, JA.; Mora, G; Figueroa-Bossi, N Article ISI SCOPUS JOURNAL OF BACTERIOLOGY (2003)
The Salmonella enterica sv. Typhimurium smvA, yddG and ompD (porin) genes are required for the efficient efflux of methyl viologen Santiviago, CA; Fuentes, JA.; Bueno, SM; Trombert, AN; Hildago, AA; Socias, LT; Youderian, P; Mora, GC Article ISI SCOPUS MOLECULAR MICROBIOLOGY (2002)
A chromosomal region surrounding the ompD porin gene marks a genetic difference between Salmonella typhi and the majority of Salmonella serovars Bucarey, SA; Mora, GC Article ISI MICROBIOLOGY-SGM (2001)


Unnecessary baggage Maloy G BookSection (2012)

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Loss of key functions drive Salmonella Typhi adaptive pathogenesis to humans Guido C Mora Proyecto (2015)
Formulación de un Compuesto Farmacéutico efectivo contra Bacterias Multirresistente de Importancia Médica Guido Mora Proyecto (2012)
Identification and analysis of pseudogenes involved in the evolutionary adaptation of Salmonella Typhi to the human host Guido Mora Proyecto (2011)
Salmonella enterica serovar Typhi, patógeno específico y crónico del ser humano: Caracterización de mecanismos moleculares de su patogenicidad Guido Mora Proyecto (2006)
Participación de las proteínas de membrana externa OmpD y OmpW de Salmonella enterica serovar Typhimurium en la expulsión de sustancias toxicas desde la célula Guido Mora Proyecto (2005)
Genómica funcional en Salmonella Typhi: Evaluación del rol de regiones cromosomales serovar-específicas en patogenicidad y especificidad de hospedero Proyecto (2002)

Patricio Retamal

Profesor Asociado

Medicina Preventiva Animal

FACULTAD DE CIENCIAS VETERINARIAS Y PECUARIAS, UNIVERSIDAD DE CHILE

Santiago, Chile

Marco Soto

Profesor Asociado

Química Física

Pontificia Universidad Católica de Chile

Santiago, Chile

Alexis Kalergis

Full Professor

Microbiología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE. FACULTAD DE CIENCIAS BIOLÓGICAS

Santiago, Chile

Susan Bueno

Profesor Asociado

Genética Molecular y Microbiología

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

SERGIO BUCAREY

Profesor Asociado

Departamento de Ciencias Biológicas Animales

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS VETERINARIAS Y PECUARIAS

Santiago, Chile

Rubén Polanco

Associate Professor

Biological Sciences

UNIVERSIDAD ANDRÉS BELLO (UNAB)

SANTIAGO, Chile

Mauricio Farfán

Profesor Asociado

Departamento de Pediatria y Cirugia Infantil, Hospital Dr. Luis Calvo Mackenna, Facultad de Medicina, Universidad de Chile

Universidad de Chile

Providencia, Chile

Marcelo Preite

Associate Professor

Organic Chemistry

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Ramiro Arratia

DIRECTOR DOCTORADO

CIENCIAS QUIMICAS

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

Leandro Carreño

Profesor Asistente

Instituto de Ciencias Biomédicas

Universidad de Chile

Santiago, Chile

Patricia García

Jefe de Laboratorio de Microbiologia

Escuela de Medicina

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE, LABORATORIO DE MICROBIOLOGÍA

Santiago, Chile

Claudia Saavedra

Full Professor

Departmento de Ciencias de la Vida

UNIVERSIDAD ANDRÉS BELLO

Santiago, Chile

Aniela Wozniak

Coordinador de Investigación

Dept Laboratorios Clínicos

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Fernando Gil

Professor

Centro de Investigación e Innovación Biomédica

Universidad de Los Andes

Santiago, Chile

ALEXIS ASPEE

Profesor Titular

Ciencias del Ambiente

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

Nicolás Villagra

Profesor Asistente

Tecnología Médica

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

Annette Trombert

Directora de Escuela

Biotecnología

UNIVERSIDAD MAYOR, INSTITUTO DE BIOTECNOLOGÍA, CENTRO DE GENÓMICA Y BIOINFORMÁTICA

Santiago, Chile

IVAN CALDERON

Associate Professor / Principal Investigator/ Master in Biotechnology & Life Sciences Director

Biological Sciences

UNIVERSIDAD ANDRÉS BELLO

SANTIAGO, Chile

Manuel Gacitúa

Profesor asistente

Facultad de Ingeniería y Ciencias

Universidad Diego Portales

Santiago, Chile

Paula Rodas

Scientific affairs

Agencia Chilena para la Inocuidad Alimentaria (ACHIPIA)

Santiago, Chile

Liliana Berrocal

Académico

UNIVERSIDAD FINIS TERRAE

Santiago, Chile

Mario Castillo

Coordinador área Microbiología e Inmunología

Ciencias Químicas y Biológicas

Universidad Bernardo O'Higgins

Santiago, Chile

Nicolás Arancibia

Profesor Asistente

Universidad de Santiago

Santiago, Chile

Daniel Paredes

Associate Professor

Department of Biological Sciences

Universidad Andrés Bello

Santiago, Chile

Pablo González

Associate Professor

Molecular Genetics and MIcrobiology

Pontificia Universidad Católica de Chile

Santiago, Chile

EDUARDO HUGO MORALES SIERRA

Maria Otero

Profesor Asociado

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

Nelson Caro

Director de Centro

Centro de Investigación Austral Biotech

Universidad Santo Tomás

Santiago, Chile

Alexander Carreño

Profesor asistente

Center of Applied Nanoscience

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

Alejandro Hidalgo

Associate Professor

Escuela de Química y Farmacia

Universidad Andres Bello

Santiago, Chile

Juan Fuentes

Académico

Ciencias Biológicas

Universidad Andrés Bello

Santiago, Chile

Dayán Páez

Profesor Asociado

Facultad de Ciencias Exactas

Universidad Andrés Bello

Santiago, Chile

Alexander Carreño

Profesor asistente

Doctorado en Fisico Química Molecular

Universidad Andrés Bello

Santiago, Chile

Juan Castro

Researcher

Universidad de Chile

Santiago, Chile

Guido Mora

Académico/Investigador

Facultad Ciencias de la Salud

Universidad SEK

Santiago, Chile

Niurka Navarro

Gerente

Innovación y Desarrollo

Nutri-Omics SpA

Samtiago, Chile

Matías Jofré

Académico

Universidad Finis Terrae

Santiago, Chile

Ítalo Urrutia

Profesor Asistente

Universidad Autónoma de Chile

Santiago, Chile

Guido Carlos Mora Longa

Líneas de Investigación

Educación

Molecular Biology, UNIVERSITY OF WISCONSIN-MADISON. Estados Unidos, 1971

Licenciado en Bioquímica y Bioquímico, UNIVERSIDAD DE CHILE. Chile, 1965

Experiencia Profesional

Director Carrera Medicina Full Time

Premios y Distinciones

PREMIO

Article (36)

BookSection (1)

Proyecto (6)