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Daniel Gonzalo Paredes Sabja

Associate Professor

Universidad Andrés Bello

Santiago, Chile

The main research questions that drive our research are:1) How pathogenic C. difficile interacts with the intestinal mucosa, innate and adaptive immune system. 2) How the intestinal microbiota modulates intestinal homeostasis

Ingeniero en Alimentos, Universidad Austral de Chile. Chile, 2003
Molecular Microbiology, Oregon State University. Estados Unidos, 2009

Profesor Asistente Full Time

Universidad Andrés Bello

Facultad de Ciencias Biológicas

Santiago, Chile

2011 - 2014
Profesor Asociado Full Time

Universidad Andrés Bello

Facultad de Ciencias Biológicas

Santiago, Chile

2014 - At present

Jefe de Procesos de Ahumado Full Time

Ventisqueros

Hornopirén, Chile

2002 - 2004
Assistant Professor Full Time

Universidad Andres Bello

Santiago, Chile

2011 - 2014
Associate Professor Full Time

Universidad Andres Bello

Santiago, Chile

2014 - At present

Doctoral students trained:
Christian Brito Ph.D. in Molecular Biosciences. 2012-to date
Marjorie Pizarro Ph.D. in Biotechnology. 2013-to date
Paulina Calderón Ph.D. in Molecular Biosciences. 2014-to date
Angela Plaza Ph.D. in Molecular Biosciences. 2015-to date
Pablo Castro Ph.D. in Biotechnology. 2016-to date
Rodrigo Reyes Ph.D. in Molecular Biosciences. 2017-to date

Master students trained:
Enzo Guerrero Master in Biotechnology. 2016-to date.
Francisca Cid Master in Biotechnology. 2016-to date.
Rodrigo Reyes Master in Biochemistry. 2016-to date.
Paola Mora Master in Biotechnology. 2015-to date.
Macarena Otto Master in Biotechnology. 2015-to date.
Juan Muñoz Master in Biotechnology. 2015-to date.
Valentina Camilli Master in Biotechnology. 2015-to date.
Constanza Galilea Master in Biotechnology. 2015-2017.
Rodrigo Reyes Master in Biochemistry. 2015-2016.
Juan Pablo Peñaloza Master in Molecular Biosciences. 2015-2017
Jaime Pizarro. Master in Biochemistry. 2014-2016.
Fernando Díaz. Master in Biotechnology. 2014-2016
Pablo Castro. Master in Biotechnology. 2014-2016
Catalina Rosales Master in Biotechnology. 2014-2015
Rodrigo Pérez Master in Molecular Biosciences. 2013-2015
Glenda Cofré. Master in Biochemistry. 2012-2014.
Mauro Milano. Master in Biochemistry. 2012-2014.
Camila Miranda. Master in Biochemistry. 2012-2014.

Advisor of Research Units of undergraduate students:
Guillermo Carrasco: 2011
Glenda Cofré-Araneda: 2011-2012
Valeria Olguin: 2011-2012
Camila Miranda-Cárdenas: 2012
Angela Plaza-Garrido: 2012
Jaime Pizarro: 2012-2014
Catalina Díaz: 2012-2013.
Flavia Dorogeschi: 2013-2013

Undergraduate students:
Jonathan Barra. Veterinary Medicine. 2012.

Outstanding Doctoral Student Savery Award

OREGON STATE UNIVERSITY

Estados Unidos, 2009

Awarded to the most outstanding doctoral student (research productivity and GPA) in the College of Agricultural Sciences at the Oregon State University
Oregon Lottery Scholarship

OREGON STATE UNIVERSITY

Chile, 2009

Awarded to graduate students at OSU with academic merit in research productivity and course work
Oregon Lottery Scholarship

OREGON STATE UNIVERSITY

Chile, 2008

Awarded to graduate students at OSU with academic merit in research productivity and course work
Graduate Student Research Award

OREGON STATE UNIVERSITY

Chile, 2008

Awarded to the graduate student with the highest research productivity of the College of Veterinary Medicine at OSU.
Chilean Presidential Fellowship.

Ministerio de Planificación

Chile, 2004

Sponsors the formation of outstanding scientists covering graduate tuition and a partial stipend to pursue a Ph.D. degree.
Academic Efficiency Award.

UNIVERSIDAD AUSTRAL DE CHILE

Chile, 2003

Sponsored by “Levaduras Collico, Chile” Consisting in the highest coefficient of GPA divided in the number of semesters remained in the Universidad Austral de Chile (UACH), of students from the same promotion.
Premio al Científico Joven

SOCIEDAD DE BIOLOGIA DE CHILE

Chile, 2015

Premio al científico joven más destacado.
Premio al Científico Joven más destacado

UNIVERSIDAD ANDRES BELLO

Chile, 2016

Premio al profesor joven más destacado en cuanto a publicaciones e investigación.


Survival of Clostridium difficile spores at low water activity Deng, K., Talukdar, P.K., Sarker, M.R., Paredes-Sabja, D., Torres, J.A. Article ISI SCOPUS FOOD MICROBIOLOGY (2017)
Updates on the biology of Clostridium difficile spore. Gil, F., Lagos-Moraga, S., Calderón-Romero, P., Pizarro-Guajardo, M., Paredes-Sabja, D. Article ANAEROBE (2017)
A feed-forward loop between SroC and MgrR small RNAs modulates the expression of eptB and the susceptibility to polymyxin B in Salmonella Thyphimurium Article MICROBIOLOGY (2016)
Acyldepsipeptide antibiotics as a potential therapeutic agent against Clostridium difficile recurrent infections Gil, F. and Paredes-Sabja, D. Article ISI SCOPUS FUTURE MICROBIOLOGY (2016)
Characterization of germinants and their receptors for spores of non-food-borne Clostridium perfringens strain F4969 Banawas, S., Paredes-Sabja, D., Setlow, P., Sarker, M.R. Article ISI SCOPUS MICROBIOLOGY-SGM (2016)
Clostridium perfringens sporulation and sporulation-associated toxin production. Li, J., Paredes-Sabja, D., Sarker, M.R., McClane B.A. Article SCOPUS MICROBIOLOGY SPECTRUM (2016)
Genome Sequence of Clostridium paraputrificum 373-A1 Isolated in Chile from a Patient Infected with Clostridium difficile Guerrero-Araya, Enzo; Díaz-Yañez, Fernando; Pizaro-Guajardo, Marjorie; Valenzuela, Sandro L.; Castro-Nallar, Eduardo Article WOS-ESCI SCOPUS Genome Announcements (2016)
Lose to win: marT pseudogenization in Salmonella enterica serovar Typhi contributed to the surV-dependent survival to H2O2, and inside human macrophage-like cells Urrutia, Ítalo M.; Talamilla-Espinoza, A. Article ISI SCOPUS INFECTION GENETICS AND EVOLUTION (2016)
Predominance of Clostridium difficile ribotypes 012, 027 and 046 in a university hospital in Chile, 2012 Plaza-Garrido, A; Barra-Carrasco, J; Macias, JH; Carman, R; Fawley, WN; Wilcox, MH; Hernandez-Rocha, C; Guzman-Duran, AM; Alvarez-Lobos, M; Paredes Sabja D Article ISI SCOPUS EPIDEMIOLOGY AND INFECTION (2016)
Salmonella Typhimurium exhibits fluoroquinolone resistance mediated by the accumulation of the antioxidant molecule H2S in a CysK-dependent manner Frávega, Jorge; Inostroza, Osvaldo; Tejías, Cristóbal Article ISI JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2016)
The integrity of the exosporium layer affects tropism of Clostridium difficile epidemic R20291 spores towards components of the intestinal mucosa Mora-Uribe, P., Miranda-Cárdenas, C., Castro-Córdova, P., Gil, F., Calderón, I.C., Rodas, P., Fuentes, J.A., Banawas, S., Sarker, M.R. and Paredes-Sabja, D. Article Frontiers in Cellular and Infection Microbiology (2016)
The NarE protein of Neisseria gonorrhoeae catalyzes ADP-ribosylation of several ADP-ribose acceptors despite an N-terminal deletion Alamos-Musre, A. Said; Álvarez, Francisca P.; Osorio, Eduardo Article ISI SCOPUS FEMS MICROBIOLOGY LETTERS (2016)
Ultrastructural variability of the exosporium layer of Clostridium difficile spores from sporulating culture and biofilms. Pizarro-Guajardo, M., Calderón-Romero, P., Paredes-Sabja, D. Article APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2016)
Ultratuctural variability of the exosporium layer of Clostridium difficile spores. Pizarro-Guajardo, M., Calderón-Romero, P., Castro-Córdova, P., Mora-Uribe, P., Paredes-Sabja, D. Article APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2016)
Analysis of Vibrio vulnificus Infection Risk When Consuming Depurated Raw Oysters Deng, K; Wu, XL; Fuentes C.; Welti-Chanes, J; Paredes Sabja D; TORRES, JA Article ISI SCOPUS Journal of Food Protection (2015)
CysB-dependent upregulation of the Salmonella Typhimurium cysJIH operon in response to antimicrobial compounds that induce oxidative stress Alvarez R.; Neumann G.; Fravega J.; Diaz, F.; Tejias C.; Collao B; Fuentes, J. A.; Paredes Sabja D; Calderon I.L.; Gil, F Article ISI SCOPUS BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)
Location and stoichiometry of the protease CspB and the cortex-lytic enzyme SleC in Clostridium perfringens spores Banawas, S; Korza, G; Paredes Sabja D; Li, YF; Hao, B; Setlow, P; Sarker, MR Article ISI SCOPUS Food Microbiology (2015)
Motility modulation by the small non-coding RNA SroC in Salmonella Typhimurium Fuentes, DN; Calderon, PF; Acuña LG; Paredes Sabja D; Fuentes, JA.; Gil, F Article ISI SCOPUS FEMS Microbiology Letters (2015)
Outcome of relapsing Clostridium difficile infections do not correlate with virulence-, spore- and vegetative cell-associated phenotypes Plaza-Garrido, A; Miranda-Cardenas, C; Castro-Cordova, P; Olguin-Araneda, V; Cofre-Araneda, G; Hernandez-Rocha, C; Carman, R; Ibáñez P.; Fawley, WN; Wilcox, MH; Gil, F; Fuentes, JA.; Guzman-Duran, AM; Alvarez-Lobos, M; Paredes Sabja D Article ISI SCOPUS Anaerobe (2015)
Participation of S. Typhimurium cysJIH operon in the H2S-mediated ciprofloxacin resistance in presence of sulfate as sulfur source. Álvarez, R., Frávega, J., Rodas, P., Fuentes, J.A., Paredes-Sabja, D., Calderón, I.L. Gil, F. Article (2015)
Protein composition of the outermost exosporium-like layer of Clostridium difficile 630 spores Diaz-Gonzalez, F; Milano, M.; Olguin-Araneda, V; Pizarro-Cerda, J; Castro-Cordova, P; Tzeng, SC; Maier, CS; Sarker, MR; Paredes Sabja D Article ISI SCOPUS Journal of Proteomics (2015)
Pseudogenization of sopA and sopE2 is functionally linked and contributes to virulence of Salmonella enterica serovar Typhi Hidalgo, AA; Rodríguez L.; urrutia im; Paredes Sabja D; Gil, F; Saavedra, CP; Mora, GC; Fuentes, JA. Article ISI SCOPUS INFECTION GENETICS AND EVOLUTION (2015)
The inhibitory effects of sorbate and benzoate against Clostridium perfringens type A isolates Alnoman, M; Udompijitkul P.; Paredes Sabja D Article ISI SCOPUS FOOD MICROBIOLOGY (2015)
Updates on the sporulation process in Clostridium species Talukdar, PK; Olguin-Araneda, V; Alnoman, M; Paredes Sabja D; Sarker, MR Article ISI SCOPUS Research in Microbiology (2015)
Characterization of the collagen-like exosporium protein, BclA1, of Clostridium difficile spores Pizarro-Guajardo, M; Olguin-Araneda, V; Barra-Carrasco, J; Brito-Silva, C; Sarker, MR; Paredes Sabja D Article ISI SCOPUS ANAEROBE (2014)
Clostridium difficile spores and its relevance in the persistence and transmission of the infection Barra-Carrasco, J; Hernandez-Rocha, C; Ibáñez P.; Guzman-Duran, AM; Alvarez-Lobos, M; Paredes Sabja D Article ISI Revista chilena de infectologï¿½a (2014)
Clostridium difficile spores: a major threat to the hospital environment Barra-Carrasco, Jonathan; Paredes-Sabja, Daniel Article ISI Future Microbiology. (2014)
New amino acid germinants for spores of the enterotoxigenic Clostridium perfringens type A isolates Udompijitkul, Pathima; Alnoman, Manyam; Banawas, Saeed; Paredes-Sabja, Daniel; Sarker, Mahfuzur R. Article ISI SCOPUS FOOD MICROBIOLOGY (2014)
Performance of prognostic index in severe Clostridium difficile-associated infection. Retrospective analysis in a university hospital Hernandez-Rocha, C; Sufan, RT; Plaza-Garrido, A; Barra-Carrasco, J; Luengo, CA; Levy, GI; Lazo, PI; Guzman-Duran, AM; Paredes Sabja D; Pezoa, MEM; Alvarez-Lobos, M Article ISI Revista chilena de infectologï¿½a (2014)
Recent advances in germination of Clostridium spores Olguín-Araneda, Valeria; Banawas, Saeed; Sarker, Mahfuzur R.; Paredes-Sabja, Daniel Article ISI RESEARCH IN MICROBIOLOGY (2014)
Atypical presentation of pseudomembranous colitis localized in adenomatous polyps Hernandez-Rocha, C; Barra-Carrasco, J; Paredes Sabja D; Lezcano, G; Zoroquiain, P; Alvarez-Lobos, M Article ISI SCOPUS World Journal of Gastroenterology (2013)
High hydrostatic pressure induced inactivation of bacterial spores Sarker, Mahfuzur R.; Akhtar, Saeed; Torres, J.Aantonio; Paredes-Sabja, Daniel Article ISI CRITICAL REVIEWS IN MICROBIOLOGY (2013)
Inactivation strategy for Clostridium perfringens spores adhered to food contact surfaces. Udompijitkul, P., Alnoman, M., Paredes-Sabja, D., Sarker, M.R. Article FOOD MICROBIOLOGY (2013)
Prospective comparison of a commercial multiplex real-time PCR and an enzyme immunoassay with toxigenic culture in the diagnosis of Clostridium difficile-associated infections Hernández-Rocha, Cristian; Barra-Carrasco, Jonathan; Álvarez-Lobos, Manuel; Paredes-Sabja, Daniel; Guzmán-Durán, Ana María Article ISI Diagnostic Microbiology and Infectious Diseases (2013)
Prospective comparison of a commercial multiplex real-time polymerase chain reaction and an enzyme immunoassay with toxigenic culture in the diagnosis of Clostridium difficile-associated infections Hernandez-Rocha, C; Barra-Carrasco, J; Alvarez-Lobos, M; Paredes Sabja D; Guzman-Duran, AM Article ISI DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE (2013)
Proteases and sonication specifically remove the exosporium layer of spores of Clostridium difficile strain Escobar-Cortés, Karina; Barra-Carrasco, Jonathan; Paredes-Sabja, Daniel Article ISI JOURNAL OF MICROBIOLOGICAL METHODS (2013)
Proteases and sonication specifically remove the exosporium layer of spores of Clostridium difficile strain 630 Escobar-Cortes, K; Barra-Carrasco, J; Paredes Sabja D Article ISI SCOPUS Journal of Microbiological Methods (2013)
The Clostridium difficile Exosporium Cysteine (CdeC)-Rich Protein Is Required for Exosporium Morphogenesis and Coat Assembly Barra-Carrasco, J; Olguin-Araneda, V; Plaza-Garrido, A; Miranda-Cardenas, C; Cofre-Araneda, G; Pizarro-Guajardo, M; Sarker, MR; Paredes Sabja D Article ISI SCOPUS Journal of Bacteriology (2013)
The Clostridium perfringens Germinant Receptor Protein GerKC Is Located in the Spore Inner Membrane and Is Crucial for Spore Germination Banawas, S; Paredes Sabja D; Korza, G; Li, YF; Hao, B; Setlow, P; Sarker, MR Article ISI SCOPUS Journal of Bacteriology (2013)
Unique Regulatory Mechanism of Sporulation and Enterotoxin Production in Clostridium perfringens Ohtani, K; Hirakawa, H; Paredes Sabja D; Tashiro, K.; Kuhara, S.; Sarker, MR; Shimizu T. Article ISI SCOPUS Journal of Bacteriology (2013)
Adherence of Clostridium difficile spores to Caco-2 cells in culture Paredes Sabja D Article ISI SCOPUS Journal of Medical Microbiology (2012)
Clostridium difficile associated infections: an updated view Hernandez-Rocha, C; Naour, S; Alvarez-Lobos, M; Paredes Sabja D Article ISI Revista chilena de infectologï¿½a (2012)
Clostridium difficile Spore-Macrophage Interactions: Spore Survival Paredes Sabja D; Cofre-Araneda, G; Brito-Silva, C; Pizarro-Guajardo, M Article ISI SCOPUS PLOS ONE (2012)
Effects of wet heat treatment on the germination of individual spores of Clostridium perfringens Wang, G; Paredes Sabja D; Green C.; Setlow, P Article ISI SCOPUS Journal of Applied Microbiology (2012)
Infecciones asociadas a Clostridium difficile: una visión actualizada. Hernández-Rocha, Cristian; Naour, Sebastian; Álvarez-Lobos, Manuel; Paredes-Sabja, Daniel Article ISI Revista chilena de infectologï¿½a (2012)
Inhibitory Effects of Nisin Against Clostridium perfringens Food Poisoning and Nonfood-Borne Isolates Udompijitkul P.; Paredes Sabja D Article ISI SCOPUS Journal of Food Science (2012)
Interactions between Clostridium perfringens spores and Raw 264.7 macrophages Paredes Sabja D Article ISI SCOPUS Anaerobe (2012)
The inhibitory effect of nisin on enterotoxigenic Clostridium perfringens Type A isolates Udompijitkul, Pathima; Paredes-Sabja, Daniel; Sarker, Mahfuzur Article ISI JOURNAL OF FOOD SCIENCE (2012)
Analysis of the germination of individual Clostridium perfringens spores and its heterogeneity Wang, G; Zhang, P.; Paredes-Sabja, Daniel; Green C.; Setlow, P; Y.Q., Li Article ISI JOURNAL OF APPLIED MICROBIOLOGY (2011)
Analysis of the germination of individual Clostridium perfringens spores and its heterogeneity. Wang, G., Zhang, P., Paredes-Sabja, D., Green, C., Setlow, P., Sarker, M.R., and Y.Q., Li*. Article JOURNAL OF APPLIED MICROBIOLOGY (2011)
Clostridium perfringens tpeL is expressed during sporulation Paredes Sabja D; Sarker N. Article SCOPUS Microbial Pathogenesis (2011)
Clostridium perfringens tpeL is expressed during sporulation. Paredes-Sabja, D., Sarker, N., and M.R. Sarker*. Article MICROBIAL PATHOGENESIS (2011)
Germination of spores of Bacillales and Clostridiales: mechanisms and proteins involved. T Paredes-Sabja, D., Setlow, P., and M.R., Sarker*. Article TRENDS IN MICROBIOLOGY (2011)
Germination response of spores of the pathogenic bacterium Clostridium perfringens and Clostridium difficile to cultured human epithelial cells. Paredes-Sabja, Daniel; Sarker, Mahfuzur Article ISI JOURNAL OF MEDICAL MICROBIOLOGY (2011)
Host serum factor triggers germination of Clostridium perfringens spores lacking the cortex hydrolysis machinery Paredes Sabja D Article SCOPUS Journal of Medical Microbiology (2011)
Host serum factor triggers germination of Clostridium perfringens spores lacking the cortex lytic hydrolysis machinery. Paredes-Sabja, D., and M.R. Sarker*. . Article JOURNAL OF MEDICAL MICROBIOLOGY (2011)
Effect of a cortex-lytic enzyme, SleC, from a non-food borne Clostridium perfringens on the germination properties of SleC-lacking spores of food poisoning isolate. Paredes-Sabja, Daniel; Sarker, Mahfuzur Article ISI CANADIAN JOURNAL OF MICROBIOLOGY (2010)
Modeling of the Germination of Spores from Clostridium perfringens food poisoning isolates. Paredes-Sabja, Daniel; TORRES, J. ANTONIO Article ISI Journal of Food Process Egineering (2010)
Further characterization of Clostridium perfringens small acid soluble protein-4 (Ssp4) properties and expression. Li, J., Paredes-Sabja, D., M.R. Sarker and B.A., McClane*. Article PLoS One (2009)
Clostridium perfringens sporulation, and its relevance to pathogenesis Paredes-Sabja, Daniel; Sarker, Mahfuzur R. Article ISI Future Microbiology. (2009)
Clostridium perfringens sporulation, and its relevance to pathogenesis. Article Future Microbiology. (2009)
Further characterization of Clostridium perfringens small acid soluble protein-4 (Ssp4) properties and expression Li, Jihong; Paredes-Sabja, Daniel; Sarker, Mahfuzur R.; McClane, Bruce Article ISI PLoS One (2009)
GerO, a putative Na+/K+-H+ antiporter, is essential for normal germination of Clostridium perfringens spores Paredes-Sabja, Daniel; Setlow, Peter; Sarker, Mahfuzur R. Article ISI JOURNAL OF BACTERIOLOGY (2009)
GerO, a putative Na+/K+-H+ antiporter, is essential for normal germination of Clostridium perfringens spores. Article JOURNAL OF BACTERIOLOGY (2009)
Inorganic phosphate and sodium ion as co-germinants for spores of Clostridium perfringens type A food poisoning isolates Paredes-Sabja, Daniel; Udompijitkul, Pathima; Sarker, Mahfuzur Article ISI APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2009)
Inorganic phosphate and sodium ion as co-germinants for spores of Clostridium perfringens type A food poisoning isolates. Article APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2009)
SleC is essential for cortex peptidoglycan hydrolysis during germination of spores of the pathogenic bacterium Clostridium perfringens. Article JOURNAL OF BACTERIOLOGY (2009)
Strategy to inactivate Clostridium perfringens spores in meats Paredes-Sabja, Daniel; Akhtar, Saeed; TORRES, J. ANTONIO; Sarker, Mahfuzur Article ISI FOOD MICROBIOLOGY (2009)
Strategy to inactivate Clostridium perfringens spores in meats. Paredes-Sabja, D., Akhtar, S. , Torres, J.A., and M.R. Sarker*. Article FOOD MICROBIOLOGY (2009)
The protease CspB is essential for initiation of cortex hydrolysis and DPA release during spore germination of Clostridium perfringens type A food poisoning isolates Paredes-Sabja, Daniel; Setlow, Peter; Sarker, Mahfuzur Article ISI MICROBIOLOGY-SGM (2009)
The protease CspB is essential for initiation of cortex hydrolysis and DPA release during spore germination of Clostridium perfringens type A food poisoning isolates. Article MICROBIOLOGY (2009)
Characterization of Clostridium perfringens spores that lack SpoVA proteins and dipicolinic acid. Paredes-Sabja, D., Setlow, B., Setlow, P., and M.R. Sarker*. Article JOURNAL OF BACTERIOLOGY (2008)
Clostridium perfringens spore germination: characterization of germinants and their receptors. Paredes-Sabja, D., Torres, J.A., Setlow, P., & M.R., Sarker*. Article JOURNAL OF BACTERIOLOGY (2008)
Germination of Spores of Clostridium difficile Isolates from a Hospital Outbreak of Clostridium difficile-associated disease (CDAD). Paredes-Sabja, D. , Bond, C. , Setlow, P., Carman, R.B., and M.R. Sarker*. Article MICROBIOLOGY (2008)
Inhibitory effects of polyphosphates on Clostridium perfringens growth, sporulation and spore outgrowth. Paredes-Sabja, D., Akhtar, S. , and M.R. Sarker*. Article FOOD MICROBIOLOGY (2008)
Role of Small, Acid-soluble Spore Proteins in the Resistance of Clostridium perfringens Spores to Chemicals. Paredes-Sabja, D., Raju, D., Torres, J.A., and M.R., Sarker*. Article INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY (2008)
Roles of DacB and Spm proteins in Clostridium perfringens spore resistance to moist heat, chemicals and UV radiation. Paredes-Sabja, D., Sarker, N., Setlow, B., Setlow, P., and M.R. Sarker*. Article APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2008)
Clostridium perfringens: Sporulation, Spore Resistance and Germination. Huang, I.H., Raju, D., Paredes-Sabja, D., and M.R., Sarker*. Article Bangladesh Journal of Microbiology. (2007)
Combined effects of Hydrostatic Pressure, Temperature and pH on the Inactivation of Spores of Clostridium perfringens type A and Clostridium sporogenes in buffer solutions. Paredes-Sabja, D., Gonzalez, M., Sarker, M R., and J. A. Torres*. Article JOURNAL OF FOOD SCIENCE (2007)
Microbial growth in refrigerated meat products. Tirado, J., Paredes, D., Velazquez, G., and J.A., Torres*. Article Ciencia y Tecnologia Alimentaria. (2007)
Diagnostic accuracy of a multiplex real-time PCR product to predict Clostridium difficile ribotype 027 Barra-Carrasco, Jonathan; Hernández-Rocha, Cristian; Miranda-Cárdenas, Camila; Álvarez-Lobos, Manuel; Guzmán-Durán, Ana María; Paredes-Sabja, Daniel Article ISI ANAEROBE
Germination of spores of Bacillales and Clostridiales species: mechanisms and proteins involved. Paredes-Sabja, Daniel; Setlow, Peter; Sarker, Mahfuzur Article ISI Trends in Microbiology
Hurdle Approach to Increase the Microbial Inactivation by High Pressur Processing: Effects of Essential Oils. Gayán, Elisa; TORRES, J. ANTONIO; Paredes-Sabja, Daniel Article ISI Food Engineering Reviews
Role of GerKB in germination and outgrowth of Clostridium perfringens spores. Paredes-Sabja, Daniel; Setlow, Peter; Sarker, Mahfuzur R. Article ISI APPLIED AND ENVIRONMENTAL MICROBIOLOGY
SleC is essential for cortex peptidoglycan hydrolysis during germination of spores of the pathogenic bacterium Clostridium perfringens Paredes-Sabja, Daniel; Setlow, Peter; Sarker, Mahfuzur Article ISI JOURNAL OF BACTERIOLOGY
Survival of Clostridium difficile Spores at Low Temperatures Deng, Kai; Plaza-Garrido, Angela; TORRES, J. ANTONIO; Paredes-Sabja, Daniel Article ISI FOOD MICROBIOLOGY


Diagnostic accuracy of a multiplex real-time PCR to predict Clostridium difficile ribotype 027 Barra-Carrasco, J; Hernandez-Rocha, C; Miranda-Cardenas, C; Alvarez-Lobos, M; Duran, AMG; Paredes Sabja D Letter ISI SCOPUS Anaerobe (2013)
Epidemic Clostridium difficile Ribotype 027 in Chile Hernandez-Rocha, C; Barra-Carrasco, J; Pizarro-Guajardo, M; Ibáñez P.; Bueno, S. M.; Guzmán A.M.; Alvarez-Lobos, M; Paredes Sabja D Letter ISI SCOPUS Emerging Infectious Diseases (2012)


Clostridium difficile recurrent infection: possible implication of TA systems Gil, F; Pizarro-Guajardo, M; Alvarez R.; Garavaglia M.; Paredes Sabja D Review ISI SCOPUS Future Microbiology (2015)
High hydrostatic pressure-induced inactivation of bacterial spores Sarker, MR; Akhtar, S; TORRES, JA; Paredes Sabja D Review ISI SCOPUS Critical Reviews in Microbiology (2015)
Clostridium difficile spore biology: sporulation, germination, and spore structural proteins Paredes-Sabja, Daniel; Shen, Aimee; Sorg, Joseph Review ISI SCOPUS TRENDS IN MICROBIOLOGY (2014)
Hurdle Approach to Increase the Microbial Inactivation by High Pressure Processing: Effect of Essential Oils Gayan E.; Torres, J. A.; Paredes Sabja D Review ISI SCOPUS Food Engineering Reviews (2012)
Molecular basis of early stages of Clostridium difficile infection: germination and colonization Paredes Sabja D Review ISI SCOPUS Future Microbiology (2012)

Daniel Paredes

Associate Professor

Department of Biological Sciences

Universidad Andrés Bello

Santiago, Chile

Manuel Alvarez

Gastroenterologist and Chief of Institute of Medicine

Gastroenterology

Pontificia Universidad Católica de Chile

Santiago, Chile

IVAN CALDERON

Associate Professor / Principal Investigator/ Master in Biotechnology & Life Sciences Director

Biological Sciences

UNIVERSIDAD ANDRÉS BELLO

SANTIAGO, Chile

Juan Fuentes

Académico

Ciencias Biológicas

Universidad Andrés Bello

Santiago, Chile

Marjorie Pizarro

Asistente de Investigacion

Ciencias Biológicas

Universidad Andrés Bello

Santiago, Chile

Fernando Gil

Professor

Centro de Investigación e Innovación Biomédica

Universidad de Los Andes

Santiago, Chile

Valeria Olguín

Lab Manager

Universidad del Desarrollo

Santiago, Chile

Paula Rodas

Scientific affairs

Agencia Chilena para la Inocuidad Alimentaria (ACHIPIA)

Santiago, Chile

Angela Plaza

Postodoctorado

Ingeniería Civile en Obras Civil

Universidad de Santiago de Chile

Estación Central, Chile

Pablo Castro

Investigador Postdoctoral

Universidad de Los Andes

Santiago, Chile

Ítalo Urrutia

Profesor Asistente

Universidad Autónoma de Chile

Santiago, Chile

Guido Mora

Académico/Investigador

Facultad Ciencias de la Salud

Universidad SEK

Santiago, Chile

Christian Brito

Postdoc

Universidad Andrés Bello

Santiago, Chile

Cristian Hernández

Assistant Professor

Gastroenterology

Pontificia Universidad Católica de Chile

Santiago, Chile

Ana Guzman

MÉDICO JEFE LABORATORIO

LABORATORIO CLÍNICO

PONTIFICIA UNIVERSIDAD CATÓLICA

SANTAIGO, Chile

Paulina Calderón

Investigador Principal

Biome Therapeutics

Santiago, Chile

Sebastián Naour

Gestor Operacional de Transferencia Tecnológica

Vicerrectoría de Transferencia Tecnológica y Extensión

Universidad Tecnológica Metropolitana

Santiago, Chile

Eduardo Castro

Associate Professor

Departamento de Microbiología

Universidad de Talca

Talca, Chile

Enzo Guerrero

PhD Student

Universidad Andrés Bello

Santiago, Chile

Alejandro Hidalgo

Associate Professor

Escuela de Química y Farmacia

Universidad Andres Bello

Santiago, Chile

Sandro Valenzuela

Bioinformático

Bioinformática

Multiplex SpA

Santiago, Chile

Claudia Saavedra

Full Professor

Departmento de Ciencias de la Vida

UNIVERSIDAD ANDRÉS BELLO

Santiago, Chile

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

Patricio Ibañez

Asistant professor

Gastroenterology

PONTIFICIA UNIVERSIDAD CATOLICA

Santiago, Chile

Daniel Gonzalo Paredes Sabja

Líneas de Investigación

Educación

Ingeniero en Alimentos, Universidad Austral de Chile. Chile, 2003

Molecular Microbiology, Oregon State University. Estados Unidos, 2009

Experiencia Académica

Profesor Asistente Full Time

Profesor Asociado Full Time

Experiencia Profesional

Jefe de Procesos de Ahumado Full Time

Assistant Professor Full Time

Associate Professor Full Time

Formación de Capital Humano

Premios y Distinciones

Outstanding Doctoral Student Savery Award

Oregon Lottery Scholarship

Oregon Lottery Scholarship

Graduate Student Research Award

Chilean Presidential Fellowship.

Academic Efficiency Award.

Premio al Científico Joven

Premio al Científico Joven más destacado

Article (86)

Letter (2)

Review (5)