Man

Nicolás Alberto Villagra Marín

Profesor Asistente

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

Líneas de Investigación


Genetic basis of bacterial resistance to antibiotics; Search for natural compounds with antimicrobial activity; Clinical microbiology; Pathogenesis in Salmonella Genetic Molecular in bacteria

Educación

  •  Microbiología, Universidad Andrés Bello. Chile, 2014

Experiencia Académica

  •   Profesor Asistente Full Time

    UNIVERSIDAD ANDRES BELLO

    Medicina

    Santiago, Chile

    2015 - At present

Experiencia Profesional

  •   Profesor Asistente Full Time

    Universidad Andrés Bello

    Santiago, Chile

    2015 - At present

Formación de Capital Humano


Tutor de 1 estudiante de Magister, Ingeniería en Biotecnología, UNAB
Co-tutor de 1 estudiante de Magister, Ingeniería en Biotecnología, UNAB
Co-tutor de 2 estudiantes de Magister en Bioquímica, UNAB
Tutor, 15 estudiantes de Unidad de Investigación, Tecnología Médica, UNAB


Difusión y Transferencia


Investigador Principal proyecto FONDEF IDeA Ca12I10110, 2013-2014


Premios y Distinciones

  •   ASM International Fellowships for Latin American and the Caribbean

    American Society Microbiology

    Estados Unidos, 2012

    to perform research at the CNRS. Centre de Génétique Moléculaire. Département Expression des Gènes. Paris. Francia.


 

Article (22)

Inactivation of Glutamine Synthetase-Coding Gene glnA Increases Susceptibility to Quinolones Through Increasing Outer Membrane Protein F in Salmonella enterica Serovar Typhi
Cysteine auxotrophy drives reduced susceptibility to quinolones and paraquat by inducing the expression of efflux-pump systems and detoxifying enzymes in S. Typhimurium
Global phylogeography and ancient evolution of the widespread human gut virus crAssphage
The efflux pump inhibitor phenylalanine-arginine beta-naphthylamide (PA beta N) increases resistance to carbapenems in Chilean clinical isolates of KPC-producing Klebsiella pneumoniae
Xylose Improves Antibiotic Activity of Chloramphenicol and Tetracycline against and in a Murine Model of Skin Infection.
[Prevalence of Bartonella henselae in blood donors and risk of blood transmission in Chile].
A conditionally lethal mutant of Salmonella Typhimurium induces a protective response in mice
Expression of IroN, the salmochelin siderophore receptor, requires mRNA activation by RyhB small RNA homologues
Lose to win: marT pseudogenization in Salmonella enterica serovar Typhi contributed to the surV-dependent survival to H2O2, and inside human macrophage-like cells
SPI-9 of Salmonella enterica serovar Typhi is constituted by an operon positively regulated by RpoS and contributes to adherence to epithelial cells in culture
Pseudogenization of sopA and sopE2 is functionally linked and contributes to virulence of Salmonella enterica serovar Typhi.
stg fimbrial operon from S. Typhi STH2370 contributes to association and cell disruption of epithelial and macrophage-like cells
RpoS integrates CRP, Fis, and PhoP signaling pathways to control Salmonella Typhi hlyE expression
Porin alterations present in non-carbapenemase-producing Enterobacteriaceae with high and intermediate levels of carbapenem resistance in Chile
Synthesis of CdTe QDs/single-walled aluminosilicate nanotubes hybrid compound and their antimicrobial activity on bacteria
The carbon source influences the efflux pump-mediated antimicrobial resistance in clinically important Gram-negative bacteria
Modified Intracellular-Associated Phenotypes in a Recombinant Salmonella Typhi Expressing S. Typhimurium SPI-3 Sequences
RpoS- and Crp-dependent transcriptional control of Salmonella Typhi taiA and hlyE genes: role of environmental conditions
SmvA and not AcrB, is the major efflux pump for acriflavine and related compounds in Salmonella enterica serovar Typhimurium
The Salmonella Typhi hlyE gene plays a role in invasion of cultured epithelial cells and its functional transfer to S. Typhimurium promotes deep organ infection in mice
The cotranscribed Salmonella enterica sv. Typhi tsx and impX genes encode opposing nucleoside-specific import and export proteins
The Salmonella enterica serovar Typhi tsx gene, encoding a nucleoside-specific porin, is essential for prototrophic growth in the absence of nucleosides

Proyecto (3)

LOSS OF KEY FUNCTIONS DRIVES SALMONELLA TYPHI ADAPTIVE PATHOGENESIS TO HUMANS
Diseño de una formulación para uso farmacéutico efectiva contra bacterias multirresistentes de importancia médica
IDENTIFICATION AND ANALYSIS OF PSEUDOGENES INVOLVED IN THE EVOLUTIONARY ADAPTATION OF SALMONELLA TYPHI TO THE HUMAN HOST
19
Nicolás Villagra

Profesor Asistente

Tecnología Médica

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

14
Guido Mora

Académico/Investigador

Facultad Ciencias de la Salud

Universidad SEK

Santiago, Chile

8
Juan Fuentes

Académico

Ciencias Biológicas

Universidad Andrés Bello

Santiago, Chile

5
Alejandro Hidalgo

Associate Professor

Escuela de Química y Farmacia

Universidad Andres Bello

Santiago, Chile

4
Matías Jofré

Académico

Universidad Finis Terrae

Santiago, Chile

2
Patricia García

Jefe de Laboratorio de Microbiologia

Escuela de Medicina

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE, LABORATORIO DE MICROBIOLOGÍA

Santiago, Chile

2
Claudia Saavedra

Full Professor

Departmento de Ciencias de la Vida

UNIVERSIDAD ANDRÉS BELLO

Santiago, Chile

2
Mario Castillo

Coordinador área Microbiología e Inmunología

Ciencias Químicas y Biológicas

Universidad Bernardo O'Higgins

Santiago, Chile

2
SERGIO BUCAREY

Profesor Asociado

Departamento de Ciencias Biológicas Animales

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS VETERINARIAS Y PECUARIAS

Santiago, Chile

1
Rodrigo De la Iglesia

Profesor Asociado

Genética Molecular y Microbiología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Celia Fernandes

profesor asistente

PREVENCIÓN Y SALUD PÚBLICA ODONTOLÓGICA

Universidad de Concepcion

Concepcion, Chile

1
Nicolás Arancibia

Profesor Asistente

Universidad de Santiago

Santiago, Chile

1
Alejandra Vera

Profesor

Ciencias Básicas

Universidad Andrés Bello

Concepción, Chile

1
Nicole Trefault

Vicerrectora de Investigación

UNIVERSIDAD MAYOR

Santiago, Chile

1
Liliana Berrocal

Académico

UNIVERSIDAD FINIS TERRAE

Santiago, Chile

1
Aniela Wozniak

Coordinador de Investigación

Dept Laboratorios Clínicos

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Gerardo Gonzalez

Full Professor

Microbiology

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

1
Antonio Vega

Full Professor

Department of Food Engineering

UNIVERSIDAD DE LA SERENA

La Serena, Chile

1
Patricio Retamal

Profesor Asistente

Medicina Preventiva Animal

FACULTAD DE CIENCIAS VETERINARIAS Y PECUARIAS, UNIVERSIDAD DE CHILE

Santiago, Chile

1
Ramiro Arratia

DIRECTOR DOCTORADO

CIENCIAS QUIMICAS

UNIVERSIDAD ANDRES BELLO

Santiago, Chile