Diazl.jpg_thumb90

Sandra Lorena Diaz Ortiz

Associate Professor

Universidad del Desarrollo

Santiago, Chile

Líneas de Investigación


Resistencia antimicrobiana a los antibióticos en bacterias causantes de infecciones humanas Genomica microbiana Epidemiologia de bacterias multidrogoresistentes: MRSA, VRE, CRE...

Educación

  •  Microbiologia, Universidad Colegio Mayor de Cundinamarca . Colombia, 2004
  •  Microbiología - Biologia molecular, Pontificia Universidad Javeriana. Chile, 2013

Experiencia Académica

  •   Associate Professor Full Time

    UNIVERSIDAD DEL DESARROLLO

    Facultad de Medicina

    Santiago, Chile

    2023 - At present


 

Article (48)

Multiomics characterization of methicillin-resistant Staphylococcus aureus (MRSA) isolates with heterogeneous intermediate resistance to vancomycin (hVISA) in Latin America
Clinical characteristics, microbiology and outcomes of a cohort of patients treated with ceftolozane/tazobactam in acute care inpatient facilities, Houston, Texas, USA
Contemporary Clinical and Molecular Epidemiology of Vancomycin-Resistant Enterococcal Bacteremia: A Prospective Multicenter Cohort Study (VENOUS I)
Differences in the subgingival microbiome according to stage of periodontitis: A comparison of two geographic regions
Molecular mechanisms leading to ceftolozane/tazobactam resistance in clinical isolates of Pseudomonas aeruginosa from five Latin American countries
A Test for the Rapid Detection of the cefazolin Inoculum Effect in Methicillin-Susceptible Staphylococcus aureus
A Young Diabetic Patient With Sepsis After Gardening
Case Report: Gestational Melioidosis through Perinatal Transmission
Detection of heterogeneous vancomycin intermediate resistance in MRSA isolates from Latin America
Dynamics of bla(KPC-2) Dissemination from Non-CG258 Klebsiella pneumoniae to Other Enterobacterales via IncN Plasmids in an Area of High Endemicity
Genomic Epidemiology of Vancomycin-Resistant Enterococcus faecium (VREfm) in Latin America: Revisiting The Global VRE Population Structure
Novel Insights into the Classification of Staphylococcal beta-Lactamases in Relation to the Cefazolin Inoculum Effect
Antimicrobial sensing coupled with cell membrane remodeling mediates antibiotic resistance and virulence in Enterococcus faecalis
Bogota River anthropogenic contamination alters microbial communities and promotes spread of antibiotic resistance genes
Disrupting Membrane Adaptation Restores In Vivo Efficacy of Antibiotics Against Multidrug-Resistant Enterococci and Potentiates Killing by Human Neutrophils
Extensively Drug-Resistant Pseudomonas aeruginosa ST309 Harboring Tandem Guiana Extended Spectrum beta-Lactamase Enzymes: A Newly Emerging Threat in the United States
Genomic and Epidemiological Evidence of a Dominant Panton-Valentine Leucocidin-Positive Methicillin Resistant Staphylococcus aureus Lineage in Sri Lanka and Presence Among Isolates From the United Kingdom and Australia
In Vivo Resistance to Ceftolozane/Tazobactam in Pseudomonas aeruginosa Arising by AmpC- and Non-AmpC-Mediated Pathways (vol 2018, 9095203, 2018)
LiaR-independent pathways to daptomycin resistance in Enterococcus faecalis reveal a multilayer defense against cell envelope antibiotics
Linezolid- and Vancomycin-resistant Enterococcus faecium in Solid Organ Transplant Recipients: Infection Control and Antimicrobial Stewardship Using Whole Genome Sequencing
Mutations in cdsA and pgsA Correlate with Daptomycin Resistance in Streptococcus mitis and S. oralis
Prevalence of APOL1 Risk Variants in Afro-Descendant Patients with Chronic Kidney Disease in a Latin American Country
An Analysis of the Epidemic of Klebsiella pneumoniae Carbapenemase-Producing K. pneumoniae: Convergence of Two Evolutionary Mechanisms Creates the "Perfect Storm"
Clonal Emergence of Invasive Multidrug-Resistant Staphylococcus epidermidis Deconvoluted via a Combination of Whole-Genome Sequencing and Microbiome Analyses
In Vivo Resistance to Ceftolozane/Tazobactam in Pseudomonas aeruginosa Arising by AmpC- and Non-AmpC-Mediated Pathways
Influence of inoculum effect on the efficacy of daptomycin monotherapy and in combination with -lactams against daptomycin-susceptible enterococcus faecium harboring liasr substitutions
Phylogenomic Classification and the Evolution of Clonal Complex 5 Methicillin-Resistant Staphylococcus aureus in the Western Hemisphere
The Cefazolin Inoculum Effect Is Associated With Increased Mortality in Methicillin-Susceptible Staphylococcus aureus Bacteremia
A Prospective Cohort Multicenter Study of Molecular Epidemiology and Phylogenonnics of Staphylococcus aureus Bacterennia in Nine Latin American Countries
Ceftaroline-Resistant, DaptomycinTolerant, and Heterogeneous Vancomycin-Intermediate MethicillinResistant Staphylococcus aureus Causing Infective Endocarditis
Genomic and Molecular Characterization of Clinical Isolates of Enterobacteriaceae Harboring mcr-1 in Colombia, 2002 to 2016
Runt-Related Transcription Factor 2 Induction During Differentiation of Wharton's Jelly Mesenchymal Stem Cells to Osteoblasts Is Regulated by Jumonji AT-Rich Interactive Domain 1B Histone Demethylase
Global Spread of the Community-Associated Methicillin-Resistant Staphylococcus aureus USA300 Latin American Variant
Methicillin-Susceptible, Vancomycin-Resistant Staphylococcus aureus, Brazil
Parallel Epidemics of Community-Associated Methicillin-Resistant Staphylococcus aureus USA300 Infection in North and South America
Resistance to "last resort" antibiotics in Gram-positive cocci: The post-vancomycin era
Transferable Vancomycin Resistance in a Community-Associated MRSA Lineage
Whole-Genome Analyses of Enterococcus faecium Isolates with Diverse Daptomycin MICs
A liaF Codon Deletion Abolishes Daptomycin Bactericidal Activity against Vancomycin-Resistant Enterococcus faecalis
Daptomycin-Resistant Enterococcus faecalis Diverts the Antibiotic Molecule from the Division Septum and Remodels Cell Membrane Phospholipids
Dissecting the Mechanisms of Linezolid Resistance in a Drosophila melanogaster Infection Model of Staphylococcus aureus
Whole-Genome Analysis of a Daptomycin-Susceptible Enterococcus faecium Strain and Its Daptomycin-Resistant Variant Arising during Therapy
Correlation between Mutations in liaFSR of Enterococcus faecium and MIC of Daptomycin: Revisiting Daptomycin Breakpoints
Native Valve Endocarditis Caused by Corynebacterium striatum with Heterogeneous High-Level Daptomycin Resistance: Collateral Damage from Daptomycin Therapy?
Transferable Plasmid-Mediated Resistance to Linezolid Due to cfr in a Human Clinical Isolate of Enterococcus faecalis
Genetic Basis for In Vivo Daptomycin Resistance in Enterococci
Molecular Epidemiology of Vancomycin-Resistant Enterococcus faecium: a Prospective, Multicenter Study in South American Hospitals
Dissemination of Methicillin-Resistant Staphylococcus aureus USA300 Sequence Type 8 Lineage in Latin America

EditorialMaterial (1)

Failure of High-Dose Daptomycin for Bacteremia Caused by Daptomycin-Susceptible Enterococcus faecium Harboring LiaSR Substitutions

Errata (1)

A Prospective Cohort Multicenter Study of Molecular Epidemiology and Phylogenomics of Staphylococcus aureus Bacteremia in Nine Latin American Countries (vol 61, e00816-17, 2017)
50
Sandra Diaz

Associate Professor

Instituto de Ciencias e Innovación en Medicina

Universidad del Desarrollo

Santiago, Chile

20
Jose Munita

Profesor Asociado

Internal Medicine

FACULTAD DE MEDICINA CLINICA ALEMANA- UNIVERSIDAD DEL DESARROLLO

Santiago, Chile

1
Jose Martínez

Investigador

ICIM

Universidad del Desarrollo

LAS CONDES, Chile

1
Mauricio Latorre

Profesor Asociado

INGENIERIA

UNIVERSIDAD DE O'HIGGINS

Rancagua, Chile

1
CATALINA PRIETO

Investigadora senior

Biología

Universidad de Chile

Santiago, Chile