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Anil Prem Sadarangani Khianey

Director de Innovacion

Universidad de Los Andes

santiago, Chile

PhD. Oncologia ginecologica Innovación y transferencia tecnológica

Biomedicina, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2008
MBA, UNIVERSITY OF CALIFORNIA-SAN DIEGO. Estados Unidos, 2015
Biologo, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2003

Profesor Full Time

UNIVERSIDAD DE LOS ANDES

Chile

2015 - At present

Post Doc Full Time

university of california san diego

San Diego, Estados Unidos

2008 - 2015
Subdirector de Desarrollo Tecnológico y Comercialización Full Time

Universidad de los Andes

Santiago, Chile

2015 - 2018
Director de Innovación Full Time

Universidad de los Andes

Santiago, Chile

2018 - At present

Director de Magíster en Innovación, Diplomado de Innovación, Minor de Innovación
de la Facultad de Ciencias Económicas y Empresariales

Líder de programa de emprendimiento KALPA, KALPA SCIENCE y KUNAY en la Región de Antofagasta.

RTTP

ATTP

Estados Unidos, 2018

Certification como agente de transferencia tecnologica (RTTP)
Beca Presidente Republica

Gobierno de Chile

Chile, 2008

BEca otorgada por Presidente Bachelet
Premio Transferencia Tecnológica

CORPORACION DE FOMENTO DE LA PRODUCCION

Chile, 2017

Categoría Profesionales de la Transferencia Tecnológica


ADAR1 Activation Drives Leukemia Stem Cell Self-Renewal by Impairing Let-7 Biogenesis Zipeto, Maria Anna; Sadarangani, Anil; Chun, Hye-Jung; Mason, Cayla N.; Geron, Ifat; Barrett, Christian; Goff, Daniel J.; Wall, Russell; Pellecchia, Maurizio; Frazer, Kelly A.; et al. Article ISI CELL STEM CELL (2016)
RNA Splicing Modulation Selectively Impairs Leukemia Stem Cell Maintenance in Secondary Human AML Crews, Leslie A.; Balaian, Larisa; Delos Santos, Nathaniel P.; Leu, Heather S.; Lazzari, Elisa; Sadarangani, Anil; Zipeto, Maria A.; La Clair, James J.; Villa, Reymundo; Kulidjian, Anna; et al. Article ISI CELL STEM CELL (2016)
GLI2 inhibition abrogates human leukemia stem cell dormancy Sadarangani, Anil; Lennon, Kathleen M.; Shih, Alice; Schairer, Annelie E.; Prashad, Sacha L.; McPherson, John D.; Moore, Richard A.; Pu, Minya; Bao, Lei; Jackson-Fisher, Amy; et al. Article ISI JOURNAL OF TRANSLATIONAL MEDICINE (2015)
Pre-clinical Specificity and Safety of UC-961, a First-In-Class Monoclonal Antibody Targeting ROR1 Choi, Michael Y.; Widhof, George F., II; Wu, Christina C. N.; Lao, Fitzgerald; Sadarangani, Anil; Cavagnaro, Joy; Prussak, Charles; Jamieson, Catriona; Kipps, Thomas J. Article ISI CLINICAL LYMPHOMA MYELOMA LEUKEMIA (2015)
Reversion to an embryonic alternative splicing program enhances leukemia stem cell self-renewal Holm, Frida; Hellqvist, Eva; Ali, Shawn A.; Delos-Santos, Nathaniel; Runza, Valeria; Sadarangani, Anil Article ISI PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia Shlush, Liran I.; Zandi, Sasan; Mitchell, Amanda; Chen, Weihsu Claire; Gupta, Vikas; Kennedy, James A.; Schimmer, Aaron D.; Schuh, Andre C.; Yee, Karen W.; McLeod, Jessica L.; et al. Article ISI Nature (2014)
Telomerase Expression Abrogates Rapamycin-Induced Irreversible Growth Arrest of Uterine Fibroid Smooth Muscle Cells Suo, Guangli; Sadarangani, Anil; Tang, Wingchung; Cowan, Bryan D.; Wang, Jean Y. J. Article ISI REPRODUCTIVE SCIENCES (2014)
A Pan-BCL2 Inhibitor Renders Bone-Marrow-Resident Human Leukemia Stem Cells Sensitive to Tyrosine Kinase Inhibition Recart, Angela Court; Sadarangani, Anil; Krajewska, Maryla; Leu, Heather; Low-Marchelli, Janine; Wei, Jun; Zhai, Dayong; Chuang, Ryan; Gotlib, Jason; Martinelli, Giovanni; et al. Article ISI CELL STEM CELL (2013)
ADAR1 promotes malignant progenitor reprogramming in chronic myeloid leukemia Isquith, Jane M.; Sadarangani, Anil; Rusert, Jessica M.; Dao, Kim-Hien T.; Goldstein, Lawrence S. B. Article ISI PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
NOTCH1 Signaling Promotes Human T-Cell Acute Lymphoblastic Leukemia Initiating Cell Regeneration in Supportive Niches Ma, Wenxue; Gutierrez, Alejandro; Sadarangani, Anil; Jamieson, Christina A. M.; Shih, Alice Y.; Wu, Christina C.; Li, Kang; Smith, Kristen M.; Gibson, Neil W.; Deichaite, Ida; et al. Article ISI PLOS ONE (2012)
Expression Profiling of Protein Tyrosine Kinases and Their Ligand Activators in Leiomyoma Uteri Jiang, Yong; Sadarangani, Anil; Cowan, Bryan Article ISI SYSTEMS BIOLOGY IN REPRODUCTIVE MEDICINE (2010)
Lipophilic but not hydrophilic statins selectively induce cell death in gynaecological cancers expressing high levels of HMGCoA reductase Kato, S; Smalley S.; Sadarangani, A; Chen-Lin, K; Oliva, B.; Brañes J.; Carvajal, J.; Gejman, R; Owen, GI; Cuello, M. Article ISI SCOPUS Journal of Cellular and Molecular Medicine (2010)
Murine Xenograft Model for Human Uterine Fibroids: An In Vivo Imaging Approach Sadarangani, Anil; LaMarca, Babbette Article ISI REPRODUCTIVE SCIENCES (2009)
2-Methoxyestradiol Mediates Apoptosis Through Caspase-Dependent and Independent Mechanisms in Ovarian Cancer Cells But Not in Normal Counterparts Kato, S; Sadarangani, A; Lange S.; Vargas, M.; Brañes J.; Carvajal, J.; Lipkowitz, S; Owen, GI; Cuello, MA Article ISI SCOPUS REPRODUCTIVE SCIENCES (2008)
The oestrogen metabolite 2-methoxyoestradiol alone or in combination with tumour necrosis factor-related apoptosis-inducing ligand mediates apoptosis in cancerous but not healthy cells of the human endometrium Kato, S; Sadarangani, A; Lange S.; Villalón, M; Brañes J.; Brosens, JJ; Owen, GI; Cuello, M. Article ISI SCOPUS ENDOCRINE-RELATED CANCER (2007)
TRAIL mediates apoptosis in cancerous but not normal primary cultured cells of the human reproductive tract Sadarangani, A; Kato, S; Espinoza, N; Lange S.; Llados, C; Espinosa,M; Villalón, M; Lipkowitz, S; Cuello, M.; Owen, GI Article ISI SCOPUS APOPTOSIS (2007)
In vivo and in vitro estrogenic and progestagenic actions of Tibolone Sadarangani, A; Salgado, AN; Kato, S; Pinto, M; Carvajal A.; Monso, C; Owen, GI; Vigil, P Article ISI SCIELO SCOPUS BIOLOGICAL RESEARCH (2005)
Progesterone increases tissue factor gene expression, procoagulant activity, and invasion in the breast cancer cell line ZR-75-1 Kato, S; Pinto, M; Carvajal A.; Espinoza, N; Monso, C; Sadarangani, A; Villalón, M; Brosens, JJ; White, JO; Richer, JK; et al. Article ISI SCOPUS JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2005)
Progesterone pre-treatment potentiates EGF pathway signaling in the breast cancer cell line ZR-75 Carvajal A.; Espinoza, N; Kato, S; Pinto, M; Sadarangani, A; Monso, C; Aranda, E; Villalón, M; Richer, JK; Horwitz, KB; et al. Article ISI SCOPUS BREAST CANCER RESEARCH AND TREATMENT (2005)


Establishment and characterization of a human uterine sarcoma cell line sensitive to TNF-related apoptosis inducing ligand plus doxorubicin. Cuello, MA; Kato, S; Sadarangani, A; Owen, GI Abstract ISI REPRODUCTIVE SCIENCES (2008)
2-methoxiestradiol induces apoptosis in gynecologic cancer cells but not in normal cell lines established from reproductive tissues. Cuello, MA; Kato, S; Sadarangani, A; Espinoza, N; Lange S.; Villalón, M; Owen, G Abstract ISI JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION (2006)
2-Methoxyestradiol induces apoptosis in ovarian cancer cells but not in normal cells Kato, S; Sadarangani, A; Espinoza, N; Lange S.; Owen, G; Cuello, M. Abstract ISI PLACENTA (2006)
Characterization and phenotypic variation with passage number of cultured human endometrial adenocarcinoma cells. Kato, S; Cuello, MAA; Espinoza, N; Lange S.; Sadarangani, A; Owen, G Abstract ISI JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION (2006)
TNF-related apoptosis inducing ligand (TRAIL) induces apoptosis in endometrial cancer cells but not in normal cells. Cuello, MA; Sadarangani, A; Kato, S; Espinoza, N; Owen, GI Abstract ISI JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION (2005)


TRAIL mediates apoptosis in cancerous but not normal primary cultured cells of the human reproductive tract (vol 12, pg 73, 2007) Sadarangani, A; Kato, S; Espinoza, N; Lange S.; Llados, C; Espinosa,M; Villalón, M; Lipkowitz, S; Cuello, M.; Owen, GI Errata ISI APOPTOSIS (2007)