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Carlos Lorenzo González Correa

Profesor Asociado

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

Basic microbiology and Bacterial Pathogenesis

Bioquímico, UNIVERSIDAD DE CONCEPCION. Chile, 1978
Microbiology, UNIVERSIDAD DE CONCEPCION. Chile, 1984
Biology /Microbiology, UNIVERSIDAD DE CHILE. Chile, 1998

PROFESOR ASOCIADO Full Time

UNIVERSIDAD DE CONCEPCION (UCO)

Ciencias Biológicas

Concecpión., Chile

1977 - 2014

Profesor Asociado Full Time

Universidad de Concepción

Concepción, Chile

1999 - At present
Miembro Sub-Comité de Pregrado Part Time

Comisión Nacional de Acreditación

Santiago, Chile

2009 - 2011

1. María Alejandra Soto Labra
ESTUDIO IN VITRO DE LA ACTIVIDAD ANTIBACTERIANA DE METRONIDAZOL Y AMOXICILINA SOLOS Ó EN ASOCIACIÓN CON RABEPRAZOL SOBRE CEPAS CLÍNICAS DE HELICOBACTER PYLORI
Fecha Graduación: 31-07-2008

2. Susana Pineda Contreras
CARACTERIZACIÓN MICROBIOLÓGICA Y DETECCIÓN MOLECULAR DE BACTERIOCINAS EN CEPAS DE LACTOBACILLUS SPP. CON POTENCIAL PROBIÓTICOS, AISLADAS DE BIOPSIAS GÁSTRICAS
Fecha Graduación: 08-07-2009

3. Felipe Contreras Rojas
DETECCIÓN MOLECULAR Y FENOTÍPICA DE PROTEÍNAS CSP EN BACTERIAS PSICROTOLERANTES, AISLADAS DEL TERRITORIO PATAGÓNICO Y ANTARTICO CHILENO
Fecha Graduación: 29-08-2011

4. Pilar Suarez Roa
Proteína "Putativa" tipo Yeaz de Helicobacter pylori en la Reversión del Estado Viable no Cultivable
Fecha Proyecto: 28-09-2012
EN EJECUCIÓN

5. José Freire Contreras
Actividad Profiláctica in vitro anti-Helicobacter pylori de Propóleos de la Región del Bío Bío
Fecha Proyecto: 02-12-2013
EN EJECUCIÓN

ECFMG Fellow

NEW YORK MEDICAL COLLEGE

Estados Unidos, 1986

Teaching medical students training and research


Lactobacillus fermentum UCO-979C strongly inhibited Helicobacter pylori SS1 in Meriones unguiculatus Merino, J.S. Article ISI SCOPUS BENEFICIAL MICROBES (2018)
Association between cagA, vacAi, and dupA genes of Helicobacter pylori and gastroduodenal pathologies in Chilean patients Paredes-Osses, E.a, Sáez, K.b, Sanhueza, E.a, Hebel, S.c, González, C.c, Briceño, C.d, García Cancino, A Article ISI SCOPUS FOLIA MICROBIOLOGICA (2017)
Characterization of Lactobacillus fermentum UCO-979C, a probiotic strain with a potent anti-Helicobacter pylori activity García, A.a , Navarro, K.a, Sanhueza, E.a, Pineda, S.a, Pastene, E.b, Quezada, M.c, Henríquez, K.b, Karlyshev, A.d, Villena, J.e, González, C. Article ISI SCOPUS Electronic Journal of Biotechnology (2017)
Persistent organic pollutants and porphyrins biomarkers in penguin. faeces from Kopaitic Island and Antarctic Peninsula Servos, Mark R.; Munkittrick, Kelly R. Article ISI SCOPUS SCIENCE OF THE TOTAL ENVIRONMENT (2016)
Dormancy in Deinococcus sp. UDEC-P1 as a survival strategy to escape from deleterious effects of carbon starvation and temperature Guerra, M., González, K., González, C., Parra, B., Martínez, M. Article Dormancy in Deinococcus sp. UDEC-P1 as a survival strategy to escape from deleterious effects of carbon starvation and temperature INTERNATIONAL MICROBIOLOGY (2015)
Draft genome sequence of a probiotic strain, Lactobacillus fermentum UCO-979C Karlyshev, A.V.a , Villena, J.b, Gonzalez, C.c, Albarracin, L.b, Barros, J.c, Garcia, A.c Article Draft genome sequence of a probiotic strain, Lactobacillus fermentum UCO-979C Genome Announcements (2015)
Effect of pH in the survival of Lactobacillus salivarius strain UCO_979C wild type and the ph acid acclimated variant Sanhueza, E., Paredes-Osses, E., González, C.L., García, A. Article Effect of pH in the survival of Lactobacillus salivarius strain UCO_979C wild type and the ph acid acclimated variant Electronic Journal of Biotechnology (2015)
Probiotic Lactobacillus fermentum UCO-979C biofilm formation on AGS and Caco-2 cells and Helicobacter pylori inhibition Salas-Jara, M.J.a, Sanhueza, E.A.a, Retamal-Díaz, A.b, González, C.a, Urrutia, H.c, García, A.a Article Probiotic Lactobacillus fermentum UCO-979C biofilm formation on AGS and Caco-2 cells and Helicobacter pylori inhibition BIOFOULING (2015)
Biofilm and Helicobacter pylori: From environment to human host García, A. , Salas-Jara, M.J., Herrera, C., González, C. Article Helicobacter pylori (H. pylori) is a Gram negative pathogen that selectively colonizes the human gastric epithelium. Over 50% of the world population is infected with H. pylori reaching up to 90% of infected individuals in developing countries. Nonetheless the increased impact upon public health care, its reservoir and the transmission pathway of the species has not been clearly established yet. Molecular studies allowed the detection of H. pylori in various aquatic environments, even forming biofilm in tap water distribution systems in several countries, suggesting a role of water as a possible reservoir of the pathogen. The persistence of human infection with H. pylori and the resistance of clinical isolates to commonly used antibiotics in eradication therapy have been related to the genetic variability of the species and its ability to develop biofilm, demonstrated both in vivo and in vitro experiments. Thus, during the last years, experimental work with this pathogen has been focused in the search for biofilm inhibitors and biofilm destabilizing agents. However, only two anti- H. pylori biofilm disrupting agents have been successfully used: Curcumin - a natural dye - and N-acetyl cysteine - a mucolytic agent used in respiratory diseases. The main goal of this review was to discuss the evidences available in the literature supporting the ability of H. pylori to form biofilm upon various surfaces in aquatic environments, both in vivo and in vitro. The results published and our own observations suggest that the ability of H. pylori to form biofilm may be important for surviving under stress conditions or in the spread of the infection among humans, mainly through natural water sources and water distribution systems. © 2014 Baishideng Publishing Group Inc. All rights reserved. WORLD JOURNAL OF GASTROENTEROLOGY (2014)
Herbicides induce change in metabolic and genetic diversity of bacterial community from a cold oligotrophic lake Aguayo P.; Gonzalez, C.; Barra, R; Becerra, J.; Martínez M Article ISI WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY (2014)
Antibacterial metabolites synthesized by psychrotrophic bacteria isolated from cold-freshwater environments Barros, J; Becerra, J.; Gonzalez, C.; Martínez M Article ISI SCOPUS Folia Microbiologica (2013)
Low co-existence rates of Lactobacillus spp. and Helicobacter pylori detected in gastric biopsies from patients with gastrointestinal symptoms Garcia, A.; Saez, K; Delgado C. Article ISI REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS (2012)
Quorum Sensing Circuit and Reactive Oxygen Species Resistance in Deinococcus sp. Fernandez-Bunster G.; Gonzalez, C.; Barros, J; Martínez M Article ISI SCOPUS Current Microbiology (2012)
Poly-beta-Hydroxyalkanoate Exert a Protective Effect Against Carbon Starvation and Frozen Conditions in Sphingopyxis chilensis Pavez P.; Gonzalez, C.; Martínez M Article ISI SCOPUS CURRENT MICROBIOLOGY (2009)
Probiotic properties of Lactobacillus spp isolated from gastric biopsies of Helicobacter pylori infected and non-infected individuals Garcia, A.; Henríquez P.; Retamal, C; Pineda, S.; Sch, CD; Gonzalez, C. Article ISI REVISTA MEDICA DE CHILE (2009)
Genotypying of clinical isolates of Helicobacter pylori by cagA, vacA and babA2 virulence associated genes. First detection of a babA2 positive strain in Chilean patients Garcia, A.; Barra, R; Delgado C.; Kawaguchi, F; Trabal, N; Montenegro, S; Gonzalez, C. Article ISI REVISTA MEDICA DE CHILE (2006)
Increased in-vitro and in-vivo biological activity of lipopolysaccharide extracted from clinical low virulence vacA genotype Helicobacter pylori strains Salgado, F; Garcia, A.; Oñate A.; Gonzalez, C.; Kawaguchi, F Article ISI SCOPUS JOURNAL OF MEDICAL MICROBIOLOGY (2002)
In vitro antimicrobial susceptibility of Helicobacter pylori strains isolated in Chile Gonzalez, C.; Garcia, A.; Daroch F.; Kawaguchi, F; Solar, H; Rivera, N; Vega, E Article ISI REVISTA MEDICA DE CHILE (2001)
Effect of EDTA on the resistance of clinical isolates of Acinetobacter baumannii to the bactericidal activity of normal human serum Garcia, A.; Solar, H; Gonzalez, C.; Zemelman R. Article ISI SCOPUS JOURNAL OF MEDICAL MICROBIOLOGY (2000)
Marine bacteria tolerant to chlorophenols Martínez M; Campos, A.; Garcia, A. Article BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY (1999)
Some immunological properties of lipopolysaccharide from Acinetobacter baumannii Garcia, A.; Salgado, F; Solar, H; Zemelman R.; Oñate A. Article JOURNAL OF MEDICAL MICROBIOLOGY (1999)
Isolation, characterization and expression of a plasmid encoding chromate resistance in Pseudomonas putida KT2441 Zaror C.A. Article LETTERS IN APPLIED MICROBIOLOGY (1998)
Recovery of soluble protein after expression in Escherichia coli depends on cellular disruption conditions Gonzalez, C.; Lagos R.; Monasterio O. Article MICROBIOS (1996)


Frequency and onset of infection caused by helicobacter pylori in children of Southern Chile Trabal, N; Venegas G.; Delgado C.; Gonzalez, C.; Errazuriz, G; Hebel, E.; Garcia, A. Abstract PEDIATRIC RESEARCH (2008)
Detection and quantification of Helicobacter pylori cagA gene in gastric biopsies of Chilean patients by real-time PCR Moreno-Hernandez, JPA; Vásquez O.; Vera, J; Gonzalez, C.; Garcia, A. Abstract HELICOBACTER (2006)