Man

sergio marcelo ruiz poblete

Co-Director

Laboratory for Brain-Machine Interfaces and Neuromodulation

santiago, Chile

Líneas de Investigación


Neural basis of neuro-psychiatric disorders, Brain-Machine Imterfaces, Brain-Computer Interfaces, Cognitive Neuroscience, Neurofeedback

Educación

  •  Medicine, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2000
  •  Psychiatrist, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2005
  •  Neuroscience, EBERHARD KARLS UNIVERSITAT TUBINGEN. Alemania, 2012

Experiencia Académica

  •   Assistant Professor Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Chile

    2013 - 2016

  •   Instructor adjunto Full Time

    Instructor adjunto

    Medicine

    Santiago, Chile

    2005 - 2012

  •   Profesor Asociado Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Medicina

    Chile

    2017 - A la fecha

Experiencia Profesional

  •   Assistant Professor Full Time

    Pontificia Universidad Catolica de Chile

    Chile

    2013 - 2016

  •   Instructor Asociado Full Time

    Pontificia Universidad Catolica de Chile

    Chile

    2005 - 2012

  •   Profesor Asistente Full Time

    Pontificia Universidad Católica de Chile

    Chile

    2017 - A la fecha

Formación de Capital Humano


Theses Supervised

a) Undergraduate students at the Medicine School, Pontificia Universidad Catolica de Chile

Project: “Family relationships and mental health: Domestic violence as predictor for Major Depression”. Grant: “Research project for Residents”, Medicine School, PUC
Student:
- Luis Ignacio Álvarez Gómez 6 grade, Medicine (first and second semester 2014)

Project: “Modulating factors and impact of domestic violence on physical and mental health/ Factores moduladores e impacto de la violencia de género en la salud física y mental”.
Grant: “Interdepartmental projects”, Medicine School, PUC.
Students:
- María Ignacia Morales Vergara, 5 grade Medicine (first semester 2015)
- Saúl Gómez, 7 grade (first and second semester 2015)
- Franco Scheel Lopetegui, 7 grade (first semester 2015)
- Miguel-Ángel Farías Marambio, 7 grade (first semester 2015)

b) Postgraduate students at the Psychiatry Residence, Medicine School, PUC

- Dr Lucas Gutiérrez (2015)
Project: “Modulating factors and impact of domestic violence on physical and mental health/ Factores moduladores e impacto de la violencia de género en la salud física y mental”
Grant: “Interdepartmental projects”, Medicine School, PUC

- Dr Tomás León (2013)
Project: “Family relationships and mental health: Domestic violence as predictor for Major Depression”.
Grant: “Research project for Residents”, Medicine School, PUC

c) Direction of Master Thesis

Master Student: Pradyumna Sepúlveda
Program: School of Engineering
Institution: PUC de Chile
Grade. Magister en Ciencias de Ingeniería, Escuela de Ingeniería, PUC.
Started: August 2014
Date of thesis: December 2015
Title of the thesis: "How feedback, motor imagery and reward influence brain self-regulation using real time FMRI"

d) Direction of Doctoral Theses
1. PhD: Korhan Buyukturkoglu
Program: Graduate School of Neural & Behavioural Sciences/ International Max Planck Research School.
Institution: University of Tuebingen, Germany.
Grade: PhD in Neurosciences
Title of the thesis: "Self-regulation of Anterior Insula using Real-time fMRI and Behavioral Effects in Obsessive Compulsive Disorder"
Date of thesis: 26 -09-2014

2. PhD (c): Jaime Pereira (starting in August 2015)
Program: Doctoral Program in Neurosciences
Institution: Interdisciplinary Center for Neurosciences, PUC.

3. PhD (c) Andrea Sanchez Cardozo (starting in August 2017)
PProgram: Doctoral Program in Neurosciences
Institution: Interdisciplinary Center for Neurosciences, PUC.

e) Postdoctoral students under Sponsoring

1. Principal Investigator: Dr. Patricia Vargas Chocano
Sponsor: Sergio Ruiz
Grant: Postdoctoral Fondecyt, 2015
Title “Auto-regulacion de la actividad de las areas sensoriomotrices y su repercusion en la function motriz de individuos sanos y de pacientes victimas de un accidente vascular cerebral”
Award: 71.000.000 CLP.
Institution: PUC

2. Principal Investigator: Mohit Rana
Sponsor: Sergio Ruiz
Grant: Postdoctoral Fondecyt, 2016
Title: “Novel control of nicotine addiction using fMRI and EEG neurofeedback of the insular cortex”.
Institution: PUC

f) Member of PhD Thesis Comitte

-Part of the thesis committee of PhD candidate Mario Villena-González: Doctorado en Neurociencias PUC. “Differential allocation of attentional resources during mind wandering”. Started in July, 2014.

- Part of the thesis committee of PhD candidate Leonie Kausell: Doctorado en Neurociencias PUC. “Functional and structural neural correlates of attention and memory during bimodal (auditory/visual) stimuli in children who play a musical instrument”. Started in August, 2015

-Part of the thesis committee (president) of PhD candidate Felipe Eduardo Rojas Thomas: Doctorado en Neurosciencias PUC. Thesis title: “Effect of acute psychosocial stress on auditory and visual processing”. Started in July, 2016

-Part of the thesis committee of PhD candidate Germán Campos: Doctorado en Neurociencias PUC.. “Neural signatures of modified declarative memories as result of reconsolidation process”. Thesis project approval: 19/08/2015.


Difusión y Transferencia


-Number of Congress Presentations since 2011: 64 (sixty four)
(Posters and Oral Presentations)

-2011 - 2011: Participation as project evaluator of the National Fund for Scientific and Technological Development (FONDECYT), presented to the 2011 Regular Competition.

-2011 Apr - 2011 Apr: Appearance in the newspapper. "El Mercurio". Science and Technology Section April 14, page A17

-2011 Apr - 2011 Apr: Organization of the visits of professors Niels Birbaumer and Ranganatha Sitaram (from the Institute of Medical Psychology and Behavioral Neurobiology, Tübingen, Germany) to the 5th Conference of the Department of Psychiatry, which included dissemination in the local press El Mercurio, April 14, 2011) and intra UC (Revista Interconsulta, http://contacto.med.puc.cl/interconsulta/interconsulta.html

-2012 Dec - 2012 Dec: Appearance in the middle of communication. Letter to the Director, El Mercurio, December 27, 2012.

-2012 Sep - 2015 Aug: Research Fellow of the Institute of Medical Psychology and Behavioral Neurobiology at the University of Tuebingen, Germany: Collaborator as international researcher.

-2013 Jul - 2013 Jul: Appearance in internal communication PUC. Interconsulta Magazine, July 2013 http://medicina.uc.cl/julio-2013/dr-sergio-ruiz-publica-articulo-en-la-revista-trends-in-cognitive-science

-2013 Dec - 2013 Dec: Participation as invited speaker at the First Basque - Chilean Biomedical Research Meeting, 2-3 December, Pontificia Universidad Catolica de Chile, Santiago, Chile. Organizer of the guest speaker Dr. Ander Ramos-Murguialday (Fatronik-TECNALIA Technology, Health Technologies Department, Foundation, San Sebastian, Spain).

-2013 June - 2013 June: Appearance in newspapper. El Mercurio. Life, Science and Technology Section, Monday, June 3, page A12

-2013 Oct - 2013 Oct: Guest Exhibitor. Symposium "Difficulties in the interface of basic research to the clinic", LXVIII Congress of Psychiatry, Neurology and Neurosurgery of Chilean Society, Viña del Mar, October 2013.

-2014 Nov - 2014 Nov: Invited exhibitor of the First Seminar on Fundamentals of Psychiatry, organized by the Scientific Academy of Medical Students of the PUC, 20-21 November 2014.

-2015 Nov - 2015 Dec: Participation as invited speaker at the Third Basque - Chilean Biomedical Research Meeting, Nov 30 - Dec 1, Pontificia Universidad Catolica de Chile, Santiago, Chile.

-2015 Sep - 2015 Sep: Reviwer Panelist at the "U21 Health Sciences Doctoral Forum: A paper is more than great results". Forum is part of the "U21 Science Group Annual Meeting September 21-25, 2015, PUC"

-2016 Apr - 2016 Apr: Guest Speaker at the III Chilean Congress of Neuroradiology at the SCNR, Santiago, Chile, 25 April 2016. Brain Machine Interfaces based on Neuroimagenes: National Experience and future directions.

-2017 May - 2017 May: Guest Speaker at the "XXVII Conference on Psychiatry", University of Valparaiso, May 12, 2017

-2017 Nov - 2017 Nov: Vice-Chairman of the Conference Program Committee "Real-Time Functional Imaging and Neurofeedback 2017" to be held Nov 29-Dec 1, 2017, Nara, Japan. Http://rtfin2017.atr.jp/


Premios y Distinciones

  •   International Annual BCI Research Award, 2012

    WASHINGTON UNIVERSITY SCHOOL MEDICINE

    Estados Unidos, 2012

    Nominee for “The International Annual BCI Research Award, 2012”, for the most innovative brain computer interface project. Awarded by the Center for Innovation in Neuroscience in Technology (Washington University School of Medicine, St Louis, USA). Sponsored by g.tec medical engineering GmbH, Shiedlberg, Austria.

  •   Latin American Travel Grant

    Society for Psychophysiological Research

    Chile, 2011

    Winner of the "Latin American Travel Grant" from the "Society for Psychophysiological Research", to participate in the "Society for Psychophysiological Research (SPR) Annual Meeting, September 14-18, 2011, Boston, Massachusetts"

  •   Beca Presidente de la República 2007

    Minister of Education, Chilean government

    Chile, 2007

    Winner of “Beca Presidente de la República 2007”, scholarship given by the Minister of Education, Chilean government, for a PhD staying in Germany.

  •   Beca Alban 2007

    European Commission

    Alemania, 2007

    Winner of "Beca Alban 2007 (5ta Convocatoria del Programa AlBan )”, scholarship given by the European Commission. AlBan Office, for studies conducting to a PhD in Europe. Declined in favour of “Beca president de la República”

  •   First Research Award

    a Sociedad de Neurología Psiquiatría y Neurocirugía de Chile

    Chile, 2005

    First Research Award. Gaspar PA, Zamorano F, Ruiz S, Altayó M, Pérez C , Aboitiz F. “Working memory load and its relation with P300 amplitude and latency, in schizophrenic patients”. 60º Congress of Psychiatry, Neurology and Neurosurgery of Chilean Society (Sonepsyn) Pucón, Chile. Rev. chil. neuro-psiquiatr 2005, vol 43, Supl. nº1, p.93.

  •   Young Researcher Award

    Sociedad Chilena de Cardiología

    Chile, 1996

    Young Researcher Award. Sergio Ruiz, Daniel Morales, Eduardo Guarda. “Metalloproteinase activity in myocardium of rats exposed to endotoxin and its inhibition with doxycycline”. XXXIII Cardiology and Cardiovascular Surgery Chilean Congress. Sociedad Chilena de Cardiología. Valdivia, Chile.

  •   Best Research in Pharmacology

    Asociación Nacional Científica de Estudiantes de Medicina

    Chile, 1996

    Best Research in Pharmacology. Sergio Ruiz, Daniel Morales, Eduardo Guarda. “Metalloproteinase activity in myocardium of rats exposed to endotoxin and its inhibition with doxycycline”. XIX National Scientific Congress for Medicine Students. Universidad de la Frontera Temuco, 31 de Julio al 3 de Agosto de 1996. Temuco, Chile. Asociación Nacional Científica de Estudiantes de Medicina (ANACEM).

  •   Nominne for "The International Annual BCI Award, 2016"

    g.tec medical engineering GmbH, Austria

    Austria, 2016

    Nominne for "The International Annual BCI Award, 2016", of .tec medical engineering GmbH, Austria, "to recognize outstanding and innovative research in the field of Brain-Computer Interfaces"

  •   Concurso Patentar para Transferir

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Chile, 2017

    Winner of the "II Concurso Patentar para Transferir", of Direccion de Transferencia y Desarrollo PUC Proyect: “System and method of cessation program for nicotine addiction by using Neurofeedback technique" Inventors: Sergio Ruiz, Ranganatha Sitaram, Mohit Rana. Junio 2017.

  •   Concurso Patentar para Transferir

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Chile, 2017

    Winner of "II Concurso Patentar para Transferir, de la Direccion de Transferencia y Desarrollo PUC". Proyect: “A therapeutic system for Depression based on neurofeedback and brain-pattern classification of EEG signals (NEUMOD-DEP)" Inventors: Sergio Ruiz, Ranganatha Sitaram, Mohit Rana. Junio 2017.

  •   Aceleración "Brain Chile". Business, Research, Acceleration and Innovation

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Chile, 2017

    First Price of the "Aceleración Brain Chile". Business, Research, Acceleration and Innovation) program of Pontificia Universidad Católica de Chile, launged by Centro de Innovación UC Anacleto Angelini, Escuela de Ingeniería, y la Dirección de Transferencia y Desarrollo, con el apoyo de Banco Santander. Proyeto: "NeuroRehab Technologies: From diagnosis to treatment with neuroimaging and computational intelligence". Team: Sergio Ruiz, Ranganatha Sitaram, Mohit Rana. 2017, June.

  •   Vice-President of the Programm Commite of the Conference “Real-Time Functional Imaging and Neurofeedback 2017

    Real-Time Functional Imaging and Neurofeedback

    Japón, 2017

    Vice-President of the Programm Commitee of the Conference “Real-Time Functional Imaging and Neurofeedback 2017” Nov 29-Dic 1, 2017, Nara, Japan. http://rtfin2017.atr.jp/


 

Article (28)

Acoso escolar (bullying) como factor de riesgo de depresión y suicidio
Involvement of top-down networks in the perception of facial emotions: a magnetoencephalographic investigation
Use of Real-Time Functional Magnetic Resonance Imaging-Based Neurofeedback to Downregulate Insular Cortex in Nicotine-Addicted Smokers
Self-Regulation of the Fusiform Face Area in Autism Spectrum: A Feasibility Study With Real-Time fMRI Neurofeedback
Sleep spindle activity in children with obstructive sleep apnea as a marker of neurocognitive performance: A pilot study
Learned Control of Inter-Hemispheric Connectivity: Effects on Bimanual Motor Performance
The Effect of Wealth Shocks on Loss Aversion: Behavior and Neural Correlates
Uso de benzodiazepinas en adultos mayores en America Latina
Editorial: Learned Brain Self-Regulation for Emotional Processing and Attentional Modulation: From Theory to Clinical Applications
How feedback, motor imagery, and reward influence brain self-regulation using real-time fMRI
La compleja relación entre la salud mental y la cirugía para la obesidad: una revisión
A subject-independent pattern-based Brain-Computer Interface
Self-Regulation of Anterior Insula with Real-Time fMRI and Its Behavioral Effects in Obsessive-Compulsive Disorder: A Feasibility Study
Domestic violence in Chile / Violencia intrafamiliar en Chile y su impacto en la salud: una revisión sistemática
Real-time fMRI brain computer interfaces: Self-regulation of single brain regions to networks
Volitional control of the anterior insula in criminal psychopaths using real-time fMRI neurofeedback: a pilot study
Abnormal Neural Connectivity in Schizophrenia and fMRI-Brain-Computer Interface as a Potential Therapeutic Approach
Acquired self-control of insula cortex modulates emotion recognition and brain network connectivity in schizophrenia
Learned regulation of brain metabolism
Descripción del uso de la licencia médica psiquiátrica en un servicio especializado de atención ambulatoria
Detection of Cerebral Reorganization Induced by Real-Time fMRI Feedback Training of Insula Activation: A Multivariate Investigation
P300 amplitude is insensitive to working memory load in schizophrenia
Parametric increases of working memory load unveil a decreased alpha oscillatory activity in schizophrenia
Psychiatric sick-leaves description in a specialized outpatient service
Real-time support vector classification and feedback of multiple emotional brain states
Patrones de consumo de sustancias de una muestra no consultante de consumidores de pasta base de cocaína
Implementación de la Entrevista de Acceso Privilegiado para caracterizar consumidores de pasta base de cocaína.
Metalloproteinase activity in myocardium of rats exposed to endotoxin and its inhibition with doxycycline

Abstract (3)

THE COMPLEX RELATIONSHIP BETWEENWEIGTH LOSS SURGERY AND MENTAL HEALTH. A REVIEW
ALPHA FREQUENCY ALTERATIONS IN SCHIZOPHRENIA DURING HIGH WORKING MEMORY LOAD CONDITIONS
SELF-CONTROL OF INSULA CORTEX BY REAL-TIME FMRI MODULATES FACE EMOTION RECOGNITION AND BRAIN NETWORK CONNECTIVITY IN SCHIZOPHRENIA

BookSection (3)

Volitional Control of Neural Connectivity
Neuromodulação por ressonância magnética funcional e classificação de padrões Connectivity
Real-Time Regulation and Detection of Brain States from fMRI Signals

BookWhole (2)

Learned Brain Self-Regulation for Emotional Processing and Attentional Modulation: From Theory to Clinical Applications
The aberrant connectivity hypothesis in schizophrenia

ConferenceProceedingWhole (5)

Unraveling the cognitive mechanism of brain self-regulation learning through dynamic mathematical modeling
Volitional Regulation of the Supplementary Motor Area with fMRI-BCI neurofeedback in Parkinson’s disease: A Pilot Study
Self-control of insula cortex by real-time fMRI modulates emotion recognition and brain network connectivity in schizophrenia
Learning to self-regulate insula cortex modulates emotion recognition and neural connectivity in schizophrenia
Learned control of insular activity using fMRI Brain Computer Interface in Schizophrenia

Editorial (2)

Neurofeedback
Editorial: Learned brain self-regulation for emotional processing and attentional modulation: From theory to clinical applications

Errata (1)

Self-Regulation of Anterior Insula with Real-Time fMRI and Its Behavioral Effects in Obsessive-Compulsive Disorder: A Feasibility Study (vol 10, e0135872, 2015)

Letter (1)

Parametric increases of working memory load unveil a decreased alpha oscillatory activity in schizophrenia

Proyecto (23)

Exosomal miRNA changes as a marker of neurocognitive morbidity in children with sleep-disordered breathing
Neural Mechanism of Brain Self-regulation with Brain -Machine Interfaces and Application to Addiction
Decoding Individual Brain States of Sleep and Memories from Real-time Pattern Classification of Simultaneous fMRI and EEG Signals
Decoding Individual Brain States of Sleep and Memories from Real-time Pattern Classification of Simultaneous fMRI and EEG Signals
NEURAL UNDERPINNINGS OF MOOD IMPROVEMENTS IN HEALTHY INDIVIDUALS AND MAJOR DEPRESSION=> ENDOGENOUS MANIPULATION OF REWARD, MEMORY AND DISTRIBUTED BRAIN NETWORKS WITH REAL-TIME FMRI BRAIN-COMPUTER INTERFACES.
How reward influences brain self-regulation. Seed Fund University of Texas, Austin – Universidad Católica de Chile, Santiago
Magnetic resonance imaging technology for aging related diseases=> brain, heart and vessels
Novel control of nicotine addiction using fMRI and EEG neurofeedback of the insular cortex
Initiating collaboration between two Latin American Neuroscience Centers=> The Interdisciplinary Center for Neuroscience, Chile, and the Brain Institute of Natal, Brazil
Network dynamics and neural circuits of the brain during resting state in health and disease
Auto-regulación de la actividad de las áreas sensoriomotrices y su repercusión en la function motriz de individuos sanos y de pacientes víctimas de un accidente vascular cerebral
Control of attention in neuropsychiatric disorders=> effect of catecholaminergic treatment during goal-directed behavior in ADHD and Major Depression
A Population-based Brain Computer Interface. Applications in depression
Resonancia Magnética Funcional en combinación con Electroencefalografía. Implementación para el estudio del funcionamiento cerebral a través de un sistema Interface Cerebro Computadora
Brain computer interfaces for the enhancement of brain networks and emotion processing. Applications in depression and schizophrenia
ESTUDIO PROSPECTIVO DEL IMPACTO BIOPSICOSOCIAL DEL USO DE PASTA BASE DE COCAINA Y CLORHIDRATO DE COCAINA EN SUJETOS NO CONSULTANTES A SERVICIOS DE REHABILITACION
Control of attention in neuropsychiatric disorders: effect of catecholaminergic treatment during goal-directed behavior in ADHD and Major Depression
Family relationships and mental health: Domestic violence as predictor for Major Depression
How reward influences brain self-regulation
Initiating collaboration between two Latin American Neuroscience Centers: The Interdisciplinary Center for Neuroscience, Chile, and the Brain Institute of Natal, Brazil
Magnetic resonance imaging technology for aging related diseases: brain, heart and vessels
Modulating factors and impact of domestic violence on physical and mental health/ Factores moduladores e impacto de la violencia de género en la salud física y mental
Neuronal circuits underlying learning and decision-making processing

Review (1)

Domestic violence in Chile
49
sergio ruiz

Co-Director

Psychiatry

Laboratory for Brain-Machine Interfaces and Neuromodulation

santiago, Chile

12
Ranganatha Sitaram

Associate Professor and Director of Laboratory of Brain-Machine Interfaces and Neuromodulation

Institute for Biological and Medical Engineering, and Department of Psychiatry

Pontificia Universidad Católica de Chile

Santiago, Chile

7
Francisco Aboitiz

Profesor

Psychiatry

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

santiago, Chile

4
Francisco Zamorano

profesor asistente

CICS

Universidad del Desarrollo

Santiago, Chile

4
Pablo Gaspar

Profesor Asistente

Psiquiatria Norte

Universidad de Chile

santiago, Chile

2
Cristian Tejos

Associate professor

Department of Electrical Engineering

Pontificia Universidad Catolica de Chile

Santiago, Chile

2
TOMAS LEON

Psiquiatra

Clinica de Memoria y Neuropsiquiatría

santiago , Chile