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Ranganatha Sitaram

Associate Professor and Director of Laboratory of Brain-Machine Interfaces and Neuromodulation

Pontificia Universidad Católica de Chile

Santiago, Chile

Líneas de Investigación


The major areas of my scientific research are: Neuroimaging, Cogntiive, Social and System Neurosciences, Brain-Computer Interfaces, Brain-Machine Interfaces, Neurofeedback, Artificial Intelligence and Pattern Recognition.

Educación

  •  Neuroscience, EBERHARD KARLS UNIVERSITAT TUBINGEN. Alemania, 2008
  •  Engineering Design, PSG College of Technology, Bharathiar University. India, 1991
  •  Mechanical Engineering, Mysore University. India, 1989

Experiencia Académica

  •   Senior Research Scientist Full Time

    EBERHARD KARLS UNIVERSITAT TUBINGEN

    Medicine

    Tuebingen, Alemania

    2004 - 2009

  •   Junior Professor (Landesstelle) Full Time

    EBERHARD KARLS UNIVERSITAT TUBINGEN

    Medicine

    Tuebingen, Alemania

    2009 - 2012

  •   Assistant Professor Full Time

    University of Florida

    Engineering

    Gainesville, Estados Unidos

    2012 - 2015

  •   Associate Professor Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Santiago, Chile

    2015 - A la fecha

  •   Visiting Professor Other

    Sri Chitra Tirunal Institute of Medical Sciences and Technology

    India

    2010 - 2013

Experiencia Profesional

  •   Senior Research Fellow Full Time

    PSG College of Technology

    Coimbatore, India

    1991 - 1992

  •   Senior Engineer and Research Scientist Full Time

    Information Technology Institute

    Singapur

    1992 - 1996

  •   Project Leader Full Time

    Kent Ridge Digital Labs

    Singapur

    1996 - 1999

  •   Group Leader Full Time

    Institute for Infocomm Research (I2R)

    Singapur

    1999 - 2000

  •   Lead Scientist, Neuroinformatics Lab Full Time

    Institute for Infocomm Research (I2R)

    Singapur

    2000 - 2004

Formación de Capital Humano


Current and Previous Scientific and Engineering Courses Taught:
1. Brain-Machine Interfaces (2016 onwards, IBM 3001 – Pontificia Universidad Católica de Chile),
2. Neural Systems Modeling (2012- 2015; BME 4931 – University of Florida),
3. Brain Machine Interfaces (2012-2015; BME 6938 - University of Florida),
4. Neural Engineering (2012-2015; BME 6360 - University of Florida),
5. Introduction to Biomedical Engg (2012-2015; BME 1008 - University of Florida),
6. Medical Psychology (2004-2012; University of Tuebingen, Germany)
7. Matlab Programming (2004-2012; University of Tuebingen, Germany)
8. FMRI and fNIRS Analyses (2004-2012; University of Tuebingen, Germany)
9. Multivariate Pattern Classification (2004-2012; University of Tuebingen, Germany)
10. Functional Connectivity Analysis (2004-2012; University of Tuebingen, Germany).
11. Object Oriented Design of Software (2000-2004; Institute of Infocomm Research, Singapore).
12. Java Programming (2000-2004; Institute of Infocomm Research, Singapore).


Difusión y Transferencia


Scientific Software Tools Developed and Distributed:
1. MANAS: FMRI toolbox for offline pattern classification of brain states (Sitaram et al 2012, Rana, Sitaram et al 2013, Lee, Sitaram et al 2010)
2. tMANAS: FMRI toolbox for real-time pattern classification and feedback of brain states (Rana, Sitaram et al 2013).
3. PRADEEP: FNIRS toolbox for offline and real-time pattern classification and feedback of brain states (Robinson, Sitaram submitted).
4. TEJAS: EEG toolbox for offline and real-time pattern classification and feedback of brain states (Schmidt, Sitaram in preparation).
5. ANVITA: DTI toolbox for pattern analysis of brain structural connectivity and network (Varkuti, Sitaram et al 2011).


Premios y Distinciones

  •   Infocomm Development Authority (IDA) award

    nfocomm Development Authority (IDA)

    Singapur, 2002

    Infocomm Development Authority (IDA) award of 1 million Singapore dollars for the development of a suite of products and services based on intelligent wireless technology called SmartEdge built in Sitaram’s laboratory

  •   Indian President’s Award of Visiting Professor of Neuroscience and Neuroimaging

    Sri Chitra Tirunal Institute of Medical Sciences and Technology

    India, 2009

    Indian President’s Award of Visiting Professor of Neuroscience and Neuroimaging in the Department of Neurology, Sri Chitra Tirunal University of Medical Sciences and Technology, Trivandrum, India.


 

Article (54)

Consensus on the reporting and experimental design of clinical and cognitive-behavioural neurofeedback studies (CRED-nf checklist)
Differential frontal alpha oscillations and mechanisms underlying loss of consciousness: a comparison between slow and fast propofol infusion rates
Fractional Anisotropy changes in Parahippocampal Cingulum due to Alzheimer’s Disease
Involvement of top-down networks in the perception of facial emotions: a magnetoencephalographic investigation
Use of Real-Time Functional Magnetic Resonance Imaging-Based Neurofeedback to Downregulate Insular Cortex in Nicotine-Addicted Smokers
Brain-Machine Interface Induced Morpho-Functional Remodeling of the Neural Motor System in Severe Chronic Stroke
Functional Connectivity of Language Regions of Stroke Patients with Expressive Aphasia During Real-Time Functional Magnetic Resonance Imaging Based Neurofeedback
Self-regulation of language areas using real-time functional MRI in stroke patients with expressive aphasia
Spatial characteristics of spontaneous and stimulus-induced individual functional connectivity networks in severe disorders of consciousness
Characterization of relapsing-remitting multiple sclerosis patients using support vector machine classifications of functional and diffusion MRI data
Multilevel diffusion tensor imaging classification technique for characterizing neurobehavioral disorders
Ensemble Classification of Alzheimer's Disease and Mild Cognitive Impairment Based on Complex Graph Measures from Diffusion Tensor Images
Learned Control of Inter-Hemispheric Connectivity: Effects on Bimanual Motor Performance
The Effect of Wealth Shocks on Loss Aversion: Behavior and Neural Correlates
Editorial: Learned Brain Self-Regulation for Emotional Processing and Attentional Modulation: From Theory to Clinical Applications.
How feedback, motor imagery, and reward influence brain self-regulation using real-time fMRI
Improving Motor Corticothalamic Communication After Stroke Using Real-Time fMRI Connectivity-Based Neurofeedback.
Real-Time fMRI in Neuroscience Research and Its Use in Studying the Aging Brain
Real-Time Subject-Independent Pattern Classification of Overt and Covert Movements from fNIRS Signals.
A subject-independent pattern-based Brain-Computer Interface
Flagrant Misconduct of Reviewers and Editor: A Case Study.
Neural loss aversion differences between depression patients and healthy individuals: A functional MRI investigation.
Self-Regulation of Anterior Insula with Real-Time fMRI and Its Behavioral Effects in Obsessive-Compulsive Disorder: A Feasibility Study.
Simultaneous epidural functional near-infrared spectroscopy and cortical electrophysiology as a tool for studying local neurovascular coupling in primates.
Insula and inferior frontal triangularis activations distinguish between conditioned brain responses using emotional sounds for basic BCI communication.
Lower Limb Movement Preparation in Chronic Stroke: A Pilot Study Toward an fNIRS-BCI for Gait Rehabilitation.
Real-time fMRI brain computer interfaces: Self-regulation of single brain regions to networks
Volitional control of the anterior insula in criminal psychopaths using real-time fMRI neurofeedback: a pilot study
A toolbox for real-time subject-independent and subject-dependent classification of brain states from fMRI signals.
Abnormal Neural Connectivity in Schizophrenia and fMRI-Brain-Computer Interface as a Potential Therapeutic Approach.
Acquired self-control of insula cortex modulates emotion recognition and brain network connectivity in schizophrenia
Brain-computer interfaces for neurorehabilitation.
Neurofeedback-mediated self-regulation of the dopaminergic midbrain.
Prediction of brain-computer interface aptitude from individual brain structure.
Real-time fMRI neurofeedback: progress and challenges.
Resting State Changes in Functional Connectivity Correlate With Movement Recovery for BCI and Robot-Assisted Upper-Extremity Training After Stroke
Differences in hemodynamic activations between motor imagery and upper limb FES with NIRS.
Real-time fMRI: a tool for local brain regulation.
Toward a brain-computer interface for Alzheimer's disease patients by combining classical conditioning and brain state classification.
Using real-time fMRI to learn voluntary regulation of the anterior insula in the presence of threat-related stimuli.
Volitional control of neuromagnetic coherence.
Detection of Cerebral Reorganization Induced by Real-Time fMRI Feedback Training of Insula Activation: A Multivariate Investigation
Quantifying the link between anatomical connectivity, gray matter volume and regional cerebral blood flow: an integrative MRI study.
Real-time support vector classification and feedback of multiple emotional brain states
Reorganization of functional and effective connectivity during real-time fMRI-BCI modulation of prosody processing.
Effective functional mapping of fMRI data with support-vector machines.
Volitional control of anterior insula activity modulates the response to aversive stimuli. A real-time functional magnetic resonance imaging study.
Hemodynamic brain-computer interfaces for communication and rehabilitation.
Self-regulation of regional cortical activity using real-time fMRI: the right inferior frontal gyrus and linguistic processing.
FMRI brain-computer interface: a tool for neuroscientific research and treatment.
Real-time functional magnetic resonance imaging: methods and applications.
Regulation of anterior insular cortex activity using real-time fMRI.
Temporal classification of multichannel near-infrared spectroscopy signals of motor imagery for developing a brain-computer interface.
Acquired control of ventral premotor cortex activity by feedback training: an exploratory real-time FMRI and TMS study.

Abstract (2)

SELF-CONTROL OF INSULA CORTEX BY REAL-TIME FMRI MODULATES FACE EMOTION RECOGNITION AND BRAIN NETWORK CONNECTIVITY IN SCHIZOPHRENIA
LEARNING TO SELF-REGULATE INSULA CORTEX MODULATES EMOTION RECOGNITION AND NEURAL CONNECTIVITY IN SCHIZOPHRENIA

BookSection (5)

Volitional Control of Neural Connectivity
BCIs that use metabolic signals
Other Medical Uses of BCI Technology
Neuroimaging Meditation
Functional Magnetic Resonance based BCI

BookWhole (2)

Learned brain self-regulation for emotional processing and attentional modulation: from theory to clinical applications
Hemodynamic Brain=Computer Interfaces: Techniques and Applications

ConferencePaper (1)

Volitional regulation of the supplementary motor area with fMRI-BCI neurofeedback in Parkinson's disease: A pilot study

Editorial (1)

Editorial: Learned brain self-regulation for emotional processing and attentional modulation: From theory to clinical applications

Errata (2)

Closed-loop brain training: the science of neurofeedback (vol 18, pg 86, 2017)
Self-Regulation of Anterior Insula with Real-Time fMRI and Its Behavioral Effects in Obsessive-Compulsive Disorder: A Feasibility Study (vol 10, e0135872, 2015)

Patent (12)

A therapeutic system for Depression based on neurofeedback and brain-pattern classification of EEG signals (NEUMOD-DEP)
System and method for clinical diagnosis of Alzheimer’s disease and Mild Cognitive Impairment using multilevel pattern classification of MRI Diffusion Tensor Images (DIAMAP)
System and method of cessation program for nicotine addiction by using Neurofeedback technique.
Multimodal closed-loop BCI and peripheral stimulation for neuro-rehabilitation
Programmatic quality assessment of Images
Spatiotemporal pattern classification of brain states
Method and system for placement, monitoring and measurement of interactive advertising
Improved Method of Co-ordinating a Group of Toys
Method and Apparatus for Developing and Distributing Interactive Advertisements
Smart Interactive Billboard Device
A System for Interactive Information Display on a Billboard
Portable Reward Checkout, Reward Management and Reward Redemption System and Method

Proyecto (24)

Neural Mechanisms of Brain Self-regulation with Brain-Machine Interfaces and Application to Addiction
Decoding Individual Brain States of Sleep and Memories from Real-time Pattern Classification of Simultaneous fMRI and EEG Signals
Decoding Individual Brain States of Sleep and Memories from Realtime Pattern Classification of Simultaneous fMRI and EEG Signals
Determining Plasticity of Brain-Regulatory Mechanisms Related to Emotion Processing: A Neurofeedback Approach in Aging and Parkinson Disease
Neural underpinnings of mood improvements in healthy individuals and depression patients: endogenous manipulation of reward memory and brain networks
Neural underpinnings of mood improvements in healthy individuals and Major Depression. Endogenous manipulation of reward, memory and distributed brain networks with real-time fMRI Brain-Computer Interfaces
Diffusion Tensor Imaging compared to standard clinical measures of concussion in female and male collegiate athletes: a longitudinal survey across the college years
Enhancing Positive Affect: Learned control of the Brain’s Appetitive Circuit Using Real-Time FMRI Neurofeedback
BRAIN COMPUTER INTERFACES FOR THE ENHANCEMENT OF BRAIN NETWORKS AND EMOTION PROCESSING. APPLICATIONS IN DEPRESSION AND SCHIZOPHRENIA
Neural Basis of Brain Self-regulation using Real-time fMRI, fNIRS and Electrophysiology in Primates
Neural Basis of Brain Selfregulation using Real-time fMRI, fNIRS and Electrophysiology in Primates.
OPTOSIS: A Portable NIRSBCI with Functional Electrical Stimulation for Stroke Rehabilitation (A Mutlicountry Collaboration between Germany, India, Spain and Turkey).
OPTOSIS=> A Portable NIRS-BCI with Functional Electrical Stimulation for Stroke Rehabilitation (A Mutlicountry Collaboration between Germany, India, Spain and Turkey)
Self-Regulation of Broca’s Area using Real time fMRI in Post Stroke Aphasia patients
Self-Regulation of Broca’s Area using Real time fMRI in Post Stroke Aphasia patients
Development of a Portable Functional Near Infrared Spectroscopy Brain-Computer Interface for Stroke Rehabilitation
Neurobiological Marker for Population Differences: a Neuroeconomic Investigation with Anxiety & Depression Patients contrasted with Normal Population
Neurobiological Marker for Population Differences=> a Neuroeconomic Investigation with Anxiety & Depression Patients contrasted with Normal Population
Self-regulation of Anterior Insula in Patients of Obsessive Compulsive Disorder.
Effective Connectivity Enhancement and Behavior in Schizophrenia: An fMRI Brain-Computer Interface Study
Volitional Regulation of Brain System for Craving using Real-time fMRI Brain- Computer Interface.
Volitional Regulation of Brain System for Craving using Real-time fMRI Brain-Computer Interface
Development of Real-time Support Vector Classification in an fMRI-BCI: Applications to Stroke and Lie Detection.
Smart Wireless Meter and Smart Billboard Technologies using SmartEdge Machine-to- Machine Technology

Review (2)

Abnormal neural connectivity in schizophrenia and fMRI-brain-computer interface as a potential therapeutic approach
Learned regulation of brain metabolism
64
Ranganatha Sitaram

Associate Professor and Director of Laboratory of Brain-Machine Interfaces and Neuromodulation

Institute for Biological and Medical Engineering, and Department of Psychiatry

Pontificia Universidad Católica de Chile

Santiago, Chile

13
sergio ruiz

Co-Director

Psychiatry

Laboratory for Brain-Machine Interfaces and Neuromodulation

santiago, Chile

2
Cristian Tejos

Associate professor

Department of Electrical Engineering

Pontificia Universidad Catolica de Chile

Santiago, Chile

1
Sergio Uribe

Associated professor

Radiology

PONTIFICIA UNIVERSIDAD CATÓLICA

Santiago, Chile

1
José Egaña

Profesor Asistente

Anestesiología y Medicina Perioperatoria

Universidad de Chile

Santiago, Chile

1
Luis Cortínez

DIVISIÓN DE ANESTESIOLOGÍA, ESCUELA DE MEDICINA, PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Francisco Zamorano

profesor asistente

CICS

Universidad del Desarrollo

Santiago, Chile

1
Francisco Aboitiz

Profesor

Psychiatry

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

santiago, Chile

1
Victor Contreras

Director y Gestor de Proyectos

Anestesiologia

Pontificia Universidad Catolica de Chile

Santiago, Chile

1
CLAUDIA CARCAMO

Profesor Asistente

neurology

PONTIFICIA UNIVERSIDADA CATÓLICA DE CHILE. DEPARTAMENTO DE NEUROLOGÍA

Santiago, Chile