María Rodríguez Fernández
Profesora Asociada
PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE
Santiago, Chile
Modelamiento Matemático; Biología de Sistemas; Fisiología Cuantitativa; Monitoreo Fisiológico
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Ingeniería Química, UNIVERSIDAD DE SANTIAGO DE COMPOSTELA. España, 2001
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PhD Ingeniería Química, UNIVERSIDAD DE VIGO. España, 2007
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Profesora Asistente Full Time
PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE
Ingeniería, Medicina y Ciencias Biológicas
Santiago, Chile
2016 - 2021
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Profesora Asociada Full Time
PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE
Ingeniería, Medicina y Ciencias Biológicas
Santiago, Chile
2021 - A la fecha
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Principal Scientist Full Time
Pfizer Inc
La Jolla, Estados Unidos
2014 - 2015
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Assistant Project Scientist Full Time
University of California Santa Barbara (UCSB)
Santa Barbara, Estados Unidos
2012 - 2014
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Research Associate Full Time
Imperial College London
London, Reino Unido
2006 - 2007
MENTORING EXPERIENCE
2020-present: M.Sc. Thesis advisor for Diego de la Vega, UC.
2020-present: PhD. Thesis advisor for Rayen Valdivia, UC.
2020-present: PhD. Thesis advisor for Carlos Valle, UC.
2019-present: PhD. Thesis advisor for Javiera Cortés, UC.
2019-present PhD. Thesis advisor for Martín Miranda, UC.
2019-present: PhD. Thesis advisor for Gabriela Vargas, UC.
2019-present: M.Sc. Thesis advisor for Axel Sepúlveda, UC.
2018-2019: M.Sc. Thesis advisor for Alexis Suárez Pinto, Research topic: "Predicting chronotype from non-invasive physiological signals", UC
2017-2019: M.Sc. Thesis advisor for Maria Emilia Fresard Petit, Research topic: "Multiobjective optimization of Machine Learning models for personalized prediction of survival and thrombosis in patients with ovarian cancer", UC
THESIS COMMITTEES
Aug 2016: M.Sc. Thesis committee: Francisco Saitua, “Dynamic Genome-Scale Metabolic Modeling of the Yeast Pichia Pastoris”, Advisor: Eduardo Agosín, UC.
Jan 2017: M.Sc. Thesis committee: Rodrigo González, “Detection, Estimation and Prediction of Ingests for Predictive Control of Artificial Pancreas Systems in Patients with T1DM”, Advisor: Aldo Cipriano, UC.
Feb 2017: M.Sc. Thesis committee: Kritsye Leiva, “Kinetic Modeling for the Optimization of ?eta-Ionone Production in S. Cerevisiae”, Advisor: Eduardo Agosín, UC.
June 2017: PhD. Thesis committee: Pierre Chelle, “Towards a Patient-Specific Definition of the Antihemophilic Factor Target Rate from Thrombin Generation: Contribution of Experimental Approaches and Dynamic Models of the Coagulation Cascade”, Advisor: Michel Cournil, Ecole des Mines de Saint-Etienne, France.
October 2017 PhD. Thesis committee: Henry Humberto León Ariza, “Development of a mathematical model to establish the physiological relationship between inflammation and the autonomic nervous system”, Advisor: Daniel Alfonso Botero Rosas, Universidad de La Sabana, Colombia.
October 2017 M.Sc. Thesis committee: Francisco Matías Pinto Chávez, “Construcción de un modelo dinámico basado en interacciones metabólicas entre especies del microbioma intestinal”, Advisor: Daniel Garrido Cortés, UC.
May 2020 PhD. Thesis committee: Rodrigo Santibáñez. “Development of rule-based models for regulatory mechanisms of gene expression and bacterial metabolism”, Advisor: Daniel Garrido Cortés, UC.
2017-Teaching "Physiological Monitoring in the IoT Era" in the Diploma "Internet of Things and the Industry 4.0", Pontificia Universidad Católica de Chile, Santiago, Chile (UC).
Journal reviewer: Bioinformatics, Bioprocess and Biosystems Engineering, BMC Systems Biology, Cells, Communications in Nonlinear Science and Numerical Simulation, Computers & Chemical Engineering, IEEE/ACM Transactions on Computational Biology and Bioinformatics, IET Systems Biology, Industrial & Engineering Chemistry Research, Reliability Engineering & System Safety, PLoS Computational Biology, Statistics and Computing, Water Research, Physical Biology, Journal of Biological Rhythms.
CONICYT reviewer for FONDEF, FONDECYT and FONDEQUIP grants.
Jan 2019-Dec 2020: Member of the “Engineering 2” Fondecyt study group.
Jan 2021-Present: Director of the “Engineering 2” Fondecyt study group.
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Extraordinary doctorate award
UNIVERSIDAD DE VIGO
España, 2007
“Premio extraordinario de doctorado” (top prize for doctoral dissertations in the Spanish universities)
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Premio de Reconocimiento a la Excelencia Docente
PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE
Chile, 2021
El Premio de Reconocimiento a la Excelencia Docente es una iniciativa que reconoce y valora a integrantes del cuerpo académicos de la UC, que realizan un trabajo docente de excelencia, cumpliendo con la misión de la universidad de formar profesionales de calidad. El Premio busca destacar a quienes realizan una docencia de excelencia destacándose en el logro de todos los Principios Orientadores para una Docencia de Calidad UC.
Optimal Experiment Design, Multimodality |
Systems Biology |
Cyber-physical systems for personalized healthcare: a data-driven approach for improved management of diabetes and hypertension |
Millennium Institute for Intelligent Healthcare Engineering |
A Multi-Variable IoT-Ready Artificial Pancreas for Type 1 Diabetes Control |
Lipophilic statins inhibit the exosome-mediated and obesity-induced cancer progression: the relevance of reestablishing natural killer cell immune surveillance to delay recurrence and improve future therapeutic outcomes in high-grade serous ovarian cancer |
Vigilancia activa en cáncer de próstata: efectividad de la firma de cuatro ARNs largos no codificantes como marcador tisular de pronóstico tumoral |
Neural Mechanisms of Brain Self-regulation with Brain-Machine Interfaces and Application to Addiction |
Understanding the Circadian Rhythms of Blood Pressure in Humans through Mathematical Modeling and Computational Tools |
Modeling the Intra and Extracellular Cytokine Signaling Pathway under Heat Stroke |
SysMo-KOSMOBAC=> Ion and solute homeostasis in enteric bacteria=> an integrated view generated from the interface of modelling and biological experimentation |
Application of global sensitivity analysis for complexity reduction, parameter estimation and time series forecasting |
Nuevos métodos para la modelización y diseño de procesos térmicos emergentes en tecnología de alimentos=> modelización (MODISTER) |
Conservación de alimentos=> nuevas metodologías y herramientas avanzadas para su simulación, optimización y control (CALISO) |