Man

Daniel Antonio Garrido Cortes

Associate Professor

Pontificia Universidad Católica de Chile

Santiago, Chile

Líneas de Investigación


Research areas and interests: Food microbiology, Functional Foods, Prebiotics and Probiotics, Gut microbiome in health and metabolic diseases, microbiome therapeutics, Systems and Synthetic Biology,

Educación

  •  Food Science, emphasis in Biotechnology, UNIVERSITY OF CALIFORNIA- DAVIS. Estados Unidos, 2012
  •  Engineering in Molecular Biotechnology, UNIVERSIDAD DE CHILE. Chile, 2005
  •  University Teaching, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2018

Experiencia Académica

  •   Assistant Professor Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Engineering

    Santiago, Chile

    2013 - 2018

  •   Postdoctoral researcher Full Time

    UNIVERSITY OF CALIFORNIA- DAVIS

    Food Science and Technology

    Davis, Estados Unidos

    2012 - 2013

  •   Associate Professor Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Engineering

    Santiago, Chile

    2019 - A la fecha

Experiencia Profesional

  •   Postdoctoral Researcher Full Time

    University of California Davis

    Davis, Estados Unidos

    2012 - 2013

  •   Consultant Part Time

    Evolve Biosciences

    San Francisco, Estados Unidos

    2012 - 2013

  •   Teaching Assistant Part Time

    University of California, Davis

    Davis, Chile

    2008 - 2011

Formación de Capital Humano


Postdoctoral researchers
Dr. Daniel Medina
Dr. Pamela Thomson
Dr. Arles Urrutia

Graduates, Ph.D. in Engineering Sciences
Juan José Fuentes, 2014-2019 “Genomic Characterization of Cylindrospermopsis Raciborskii a Cyanobacterium Able to Produce Bioactive Compounds”
Rodrigo Santibáñez, 2016-2020 “Development of rule-based models for regulatory mechanisms of gene expression and bacterial metabolism”

Ph.D. students in progress
Romina Díaz (U. de la Serena), 2018-to date
Kevin González (U. de Cartagena, Colombia), 2018-to date
Marco Vega (U. de Concepción), 2018-to date
Alvaro Altamirano, 2019 to date
Aline Ovalle, 2019 to date
Alexis Torres, 2019 to date
Felipe Melis, 2020 to date
Claudia Silva (codirección; Universidad Mayor, Doctorado Genómica Integrativa)
Joaquín Gutiérrez (codirección; Doctorado Ciencias Biológicas PUC)

Graduated, Master in Engineering Sciences
Aline Ovalle, 2014-2016, graduated. “Interacciones Mediadas por Prebióticos en un Consorcio Modelo del Microbioma Intestinal Infantil”
Francisco Pinto, 2014-2017, graduated. “Construcción de un Modelo Dinámico Basado en Interacciones Metabólicas entre Especies del Microbioma Intestinal”
Natalia Gutiérrez, 2016-2018, graduated. “Deleción de Especies desde un Consorcio de Microbioma Intestinal Sugiere Interacciones Metabólicas Claves entre Microorganismos”
María José Barra, 2019-2021, graduated. “Engineered bacteria for propionate-repressed expression of sfGFP and GM-CSF”
Belén Hirmas, 2019-2021, graduated. “Bi-directional cultures reveal metabolic cross-feeding between gut commensals”
Loreto Román, 2019-2021, graduated. “Genome-Scale Metabolic Modeling of the Human Milk Oligosaccharide Utilization by Bifidobacterium Longum Subsp. Infantis”
Guillermo Orellana, 2019-2021, graduated. “Modelamiento a Escala Genómica de las Interacciones Metabolicas entre Microorganismos Comensales y Productores de Butirato”

Masters Students In progress
Kineret Serebrinsky
Javiera Munizaga
Tomás Proschle
Paula Lobos

Undergraduate Research students, Civil Engineering in Biotechnology
Gonzalo Alcaíno
Andrés Cisneros
Ignacia Cancino
Alexis Suárez
Francisco Pedreros
Guillermo Orellana
María José Barra
Bárbara Coloma
Francisca Rojas
Rosa Godoy
Martín Silva
Daniela Contador
Ricardo Leiva
Adolfo Godoy 2021
Tomás Proschle 2021
Paula Lobos 2021
Rocío Arratia 2022
María José Santibáñez 2022
Tays Troncoso 2022
Andrés Canales 2022
Diego Ulloa 2022
Kaina Galdames 2022
Michelle Gibert 2022

Undergraduate thesis, Biochemistry
Samantha Nuñez
Camila Solar
Juan Paulo Pedreros
Amalia Candia

Visiting Students
Taylor Hinchliffe, Columbia University


Difusión y Transferencia


Participación en programas Conicyt: "Un Dia con un Científico" y programa Explora dictando charlas educaciones a alumnos de educación media.
Difusión de carreras en ingeniería química y biotecnología a alumnos visitantes del programa Embajadores Ingeniería UC (Instituto O'Higgins de Rancagua, Instituto Nacional, Colegio Internacional Sek Chile, Liceo José Toribio Medina, entre otros)


Premios y Distinciones

  •   Panamerican Bimbo Award

    Bimbo

    Estados Unidos, 2013

    Bimbo Award 2013, award to the best thesis in human nutrition, United States area. Dissertation title: A molecular basis for the enrichment of bifidobacteria in the infant gastrointestinal tract”

  •   Young Investigator Oral Presentation Award

    American Societies for Microbiology

    Estados Unidos, 2012

    Young Investigator Oral Presentation Award. 111th Annual Meeting of the Association of Societies of Microbiology, San Francisco, CA, June 2012.

  •   National Dairy Leadership Scholarship Award.

    National Milk Producers Federation

    Estados Unidos, 2011

    National Milk Producers Federation (NMPF) National Dairy Leadership Scholarship Award. July 2011. Awarded to the most qualified doctoral students in dairy-related sciences in the US.

  •   Fulbright-CONICYT scholarship

    Comisión Fulbright

    Chile, 2006

    Fulbright-CONICYT scholarship for doctoral programs in the U.S. Ministry of Education and Fulbright Chile Commission, 2006.

  •   UCDavis Chile Fellow

    UNIVERSITY OF CALIFORNIA- DAVIS

    Chile, 2017

    Premio destacada trayectoria Ex-alumnos chilenos de UC Davis

  •   Malaspina International Scholar Travel (MIST) 2019 Award

    International Life Sciences Institute

    Estados Unidos, 2018

    Malaspina International Scholar Travel (MIST) 2019 Award, by the International Life Sciences Institute. One of six worldwide scholarships to support travel and engage early-career, academic scientists at the ILSI Annual Meeting and Scientific Symposium.

  •   Associate Editor mSystems

    American Societies for Microbiology

    Estados Unidos, 2020

    Parte del board of editors de la revista mSystems, parte de ASM

  •   Associate Editor Frontiers in Microbiology

    Frontiers

    Suiza, 2021

    Selected as Associate Editor for this journal. Edit 12-15 papers per year.

  •   Associate Editor - Probiotics and Antimicrobial Proteins

    Springer publishers

    Chile, 2022

    Selected as associate editor for this journal. Edit 10 papers a year.


 

Article (40)

Comparative Genomics of Clostridium baratii Reveals Strain-Level Diversity in Toxin Abundance
Differences in the composition and predicted functions of the intestinal microbiome of obese and normal weight adult dogs
Modeling approaches for probing cross-feeding interactions in the human gut microbiome
Assessment of Changes in the Oral Microbiome That Occur in Dogs with Periodontal Disease
Comparative Genomic Analysis of Novel Bifidobacterium longum subsp. longum Strains Reveals Functional Divergence in the Human Gut Microbiota
Atlas: automatic modeling of regulation of bacterial gene expression and metabolism using rule-based languages
Editorial: Systems Modeling: Approaches and Applications
Engineered Probiotics for Detection and Treatment of Inflammatory Intestinal Diseases
Inferring composition and function of the human gut microbiome in time and space: A review of genome-scale metabolic modelling tools
Molecular Insights Into O-Linked Glycan Utilization by Gut Microbes
Pleione: A tool for statistical and multi-objective calibration of Rule-based models
Short-term impact of sucralose consumption on the metabolic response and gut microbiome of healthy adults
Species Deletions from Microbiome Consortia Reveal Key Metabolic Interactions between Gut Microbes
Anti-inflammatory effect of microbial consortia during the utilization of dietary polysaccharides
Draft genome sequences of Cylindrospermopsis raciborskii strains CS-508 and MVCC14, isolated from freshwater bloom events in Australia and Uruguay
Evaluating the Capacity of Human Gut Microorganisms to Colonize the Zebrafish Larvae (Danio rerio)
Human milk oligosaccharides and infant gut bifidobacteria: Molecular strategies for their utilization
Simulation and modeling of dietary changes in the infant gut microbiome
Stochastic simulation of multiscale complex systems with PISKaS: A rule-based approach
Distinct patterns in the gut microbiota after surgical or medical therapy in obese patients
Modeling Metabolic Interactions in a Consortium of the Infant Gut Microbiome
Prebiotics Mediate Microbial Interactions in a Consortium of the Infant Gut Microbiome
A novel gene cluster allows preferential utilization of fucosylated milk oligosaccharides in Bifidobacterium longum subsp. longum SC596
Identification of Oligosaccharides in Feces of Breast-fed Infants and Their Correlation with the Gut Microbial Community
Comparative transcriptomics reveals key differences in the response to milk oligosaccharides of infant gut-associated bifidobacteria
Hydrolysis of milk gangliosides by infant-gut associated bifidobacteria determined by microfluidic chips and high-resolution mass spectrometry
Consumption of human milk glycoconjugates by infant-associated bifidobacteria: mechanisms and implications
Proteomic Analysis of Bifidobacterium longum subsp. infantis Reveals the Metabolic Insight on Consumption of Prebiotics and Host Glycans
Utilization of galactooligosaccharides by Bifidobacterium longum subsp. infantis isolates
Variation in Consumption of Human Milk Oligosaccharides by Infant Gut-Associated Strains of Bifidobacterium breve
A Molecular Basis for Bifidobacterial Enrichment in the Infant Gastrointestinal Tract
Bifidobacterium longum subsp. infantis ATCC 15697 ?-Fucosidases Are Active on Fucosylated Human Milk Oligosaccharides
Endo-β- N -acetylglucosaminidases from Infant Gut-associated Bifidobacteria Release Complex N -glycans from Human Milk Glycoproteins
Release and utilization of N-acetyl-d-glucosamine from human milk oligosaccharides by Bifidobacterium longum subsp. infantis
Oligosaccharide Binding Proteins from Bifidobacterium longum subsp. infantis Reveal a Preference for Host Glycans
Study of the coumarate decarboxylase and vinylphenol reductase activities of Dekkera bruxellensis (anamorph Brettanomyces bruxellensis) isolates
Taqman real-time PCR for the detection and enumeration of Saccharomyces cerevisiae in wine
Characterization of human intestinal bifidobacteria using competitive PCR and PCR-TTGE
Effect of a milk formula with prebiotics on the intestinal microbiota of infants after an antibiotic treatment
Modulation of the fecal microbiota by the intake of a Lactobacillus johnsonii La1-containing product in human volunteers

BookSection (2)

The Gut Microbiome after Bariatric Surgery
Human Milk Oligosaccharides and Health Promotion Through the Gut Microbiome

Patent (2)

METHODS AND COMPOSITIONS FOR IMPROVED DIGESTION OF MILK OLIGOSACCHARIDES
Enzymes and methods for cleaving N-glycans from glycoproteins

Proyecto (19)

Gene Regulatory Networks in Gut Microbiome Consortia
Design of anti-inflammatory gene circuits for gut microbiome therapeutics
Identification and Modeling of Cross-Feeding Interactions in the Gut Microbiome for Designing Microbial Communities
Implementing a Multimodal Fluorescence Reader for Research in Bioengineering.
Modeling metabolic interactions of infant gut microbes during consumption of human milk oligosaccharides
Design of Microbial Consortia for Treatment of Intestinal Inflammatory Diseases
Diseño de Consorcios Microbianos para el Tratamiento de Enfermedades Inflamatorias del Intestino
EVALUACIÓN DEL EFECTO DE LA SUCRALOSA SOBRE LA COMPOSICIÓN Y FUNCIÓN DEL MICROBIOMA INTESTINAL EN SUJETOS SANOS
“Evaluación del efecto de la sucralosa sobre la composición y función del microbioma intestinal en sujetos sanos”
Efecto de endulzantes no nutritivos sobre el metabolismo y la microbiota intestinal
Efecto de endulzantes no nutritivos sobre el metabolismo y la microbiota intestinal
Microbiome engineering and synthetic biology applications for health
Synthetic biology and microbiome applications for health. Design of biological sensors for intestinal delivery
EVALUACIÓN METAGENÓMICA DE LOS CAMBIOS EN LA COMPOSICIÓN Y FUNCIÓN DE LA MICROBIOTA INTESTINAL ASOCIADOS AL TRATAMIENTO DE LA OBESIDAD
Effect of Bariatric Surgery on the Intestinal Microbiota
A defined in vitro fermentation system to study alterations of the intestinal microbiota
A DEFINED IN-VITRO FERMENTATION SYSTEM TO EVALUATE THE IMPACT OF ALTRATIONS OF THE INTESTINAL MICROBIOTA
Effect of Bariatric Surgery on the Intestinal Microbiota
Evaluación metagenómica de los cambios en la composición y función de la microbiota intestinal asociados al tratamiento de la obesidad
60
Daniel Garrido

Associate Professor

Chemical and Bioprocess Engineering

Pontificia Universidad Católica de Chile

Santiago, Chile

6
Alberto Martin

Assistant professor

Centro de Genómica y Bioinformática

Universidad Mayor

Santiago, Chile

3
Daniel Medina

Investigador

Medicina Veterinaria

Universidad San Sebastián

Puerto Montt, Chile

3
MARTIN GOTTELAND

Profesor Titular

Facultad de Medicina

Universidad de Chile

Santiago, Chile

2
Pedro Saa

Profesor Asistente

Departmento de Ingenieria Quimica y Bioprocesos

Pontificia Universidad Catolica de Chile

Santiago, Chile

2
Claudio Martinez

Profesor Titular

Departamento de Ciencia y Tecnología de Alimentos

Universidad de Santiago de Chile

Santiago, Chile

2
MARIA GANGA

academico jornada completa

Departamento en Ciencia y Tecnologia de los Alimentos

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

2
Fabien MAGNE

Profesor asistante

UNIVERSIDAD DE CHILE

Chile

1
Magaly Toro

Profesor Asistente

UNIVERSIDAD DE CHILE

Chile

1
Carmen Feijóo

Profesor asociado

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

1
Katia Soto

Académica

Universidad de Chile

Santiago, Chile

1
José Pérez

Profesor Titular

Ingeniería Química y Bioprocesos

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

1
JOSE GALGANI

ASSOCIATE PROFESSOR

NUTRITION, DIABETES AND METABOLISM; AND UDA-CIENCIAS DE LA SALUD, NUTRICION Y DIETETICA

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Paola Navarrete

Associate Professor

INTA

Universidad de Chile

Santiago, Chile

1
Lucy Belmar

Profesor asistente adjunto

Facultad de Ciencias de la Vida

Universidad Andrés Bello

Santiago, Chile

1
Angelica Reyes

Profesor Asociado

INTA UNIVERSIDAD DE CHILE

Santiago, Chile

1
Mario Caruffo

Investigador Post-doctoral

Inmunología en Peces

Universidad Andrés Bello

Santiago, Chile

1
Guillermo Figueroa

Profesor Asociado

Laboratorio: Microbiología de Alimentos y Probióticos

INTA, Universidad de Chile

Santiago, Chile

1
Luz Vásquez

Profesor Asociado

Genética Molecular y Microbiología

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Pamela Thomson

Post Doctorado

Ingeniería Química y Bioprocesos

Universidad Católica

Santiago, Chile

1
Danilo Pérez

Investigador

Programa Institucional de Fomento a la Investigación, Desarrollo e Innovación

UNIVERSIDAD TECNOLÓGICA METROPOLITANA

Santiago, Chile

1
alejandro bernardin

PhD (c)

Fundación Ciencia y Vida

Santiago, Chile

1
Natalia Gutiérrez

Supervisora de estudios sensoriales

Evaluación Sensorial

DICTUC

Macul, Chile

1
Francisco Salinas

Profesor Auxiliar

Instituto de Bioquímica y Microbiolgía

Universidad Austral de Chile

Valdivia, Chile

1
Lliliana Godoy

Profesor Asistente

Fruticultura y Enología

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Juan Ugalde

Assistant Professor

Facultad de Ciencias de la Vida

Universidad Andrés Bello

Santiago, Chile