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Francisco Jose Salinas Sanhueza

Profesor Asociado

Universidad Austral de Chile

Valdivia, Chile

Líneas de Investigación


Genómica funcional, microbiología, genética, biología molecular y optogenética en levaduras.

Educación

  •  Doctor en Microbiología, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 2011
  •  Licenciatura en Ingeniería en Biotecnología, UNIVERSIDAD DE CHILE. Chile, 2007
  •  Ingeniero en Biotecnología Molecular, UNIVERSIDAD DE CHILE. Chile, 2008

Experiencia Académica

  •   Postdoctorado Full Time

    Université de Nice

    Facultad de Medicina

    Nice, Francia

    2012 - 2014

  •   Postdoctorado Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Facultad de Ciencias Biológicas

    Santiago, Chile

    2014 - 2017

Experiencia Profesional

  •   Investigador asociado Full Time

    Universidad de Santiago de Chile

    Santiago, Chile

    2017 - 2019

  •   Profesor Auxiliar Full Time

    Universidad Austral de Chile

    Valdivia, Chile

    2019 - 2024

  •   Profesor Asociado Full Time

    Universidad Austral de Chile

    valdivia, Chile

    2024 - A la fecha

Formación de Capital Humano


Director de tesis de pregrado: 10 tesis finalizadas.
Co-director de tesis de pregrado: 1 tesis finalizada.
Director de tesis de magister: 2 tesis finalizadas.
Director de tesis de doctorado: 4 tesis en curso.


Premios y Distinciones

  •   Mejor trabajo de incorporación

    SOCIEDAD DE BIOQUIMICA DE CHILE

    Chile, 2019

    Premio al mejor trabajo de incorporación de la Sociedad de Bioquímica y Biología Molecular de Chile (SBBMCh).


 

Article (35)

Single nucleotide polymorphisms associated with wine fermentation and adaptation to nitrogen limitation in wild and domesticated yeast strains
The N-Terminal Region of the BcWCL1 Photoreceptor Is Necessary for Self-Dimerization and Transcriptional Activation upon Light Stimulation in Yeast
A Saccharomyces eubayanus haploid resource for research studies
Expanding the molecular versatility of an optogenetic switch in yeast
Interactions between Core Elements of the <i>Botrytis cinerea</i> Circadian Clock Are Modulated by Light and Different Protein Domains
Modular and Molecular Optimization of a LOV (Light-Oxygen-Voltage)-Based Optogenetic Switch in Yeast
The rise and shine of yeast optogenetics
Comparison of Phylogenetic Tree Topologies for Nitrogen Associated Genes Partially Reconstruct the Evolutionary History of Saccharomyces cerevisiae
Differential Gene Expression and Allele Frequency Changes Favour Adaptation of a Heterogeneous Yeast Population to Nitrogen-Limited Fermentations
GTR1 Affects Nitrogen Consumption and TORC1 Activity in Saccharomyces cerevisiae Under Fermentation Conditions
Total evidence or taxonomic congruence? A comparison of methods for combining biological evidence
Transcriptional Activity and Protein Levels of Horizontally Acquired Genes in Yeast Reveal Hallmarks of Adaptation to Fermentative Environments
Genetic variants of TORC1 signaling pathway affect nitrogen consumption in Saccharomyces cerevisiae during alcoholic fermentation
Indirect monitoring of TORC1 signalling pathway reveals molecular diversity among different yeast strains
KAE1 Allelic Variants Affect TORC1 Activation and Fermentation Kinetics in Saccharomyces cerevisiae
Fungal Light-Oxygen-Voltage Domains for Optogenetic Control of Gene Expression and Flocculation in Yeast
GPD1 and ADH3 Natural Variants Underlie Glycerol Yield Differences in Wine Fermentation
Clonal Heterogeneity Influences the Fate of New Adaptive Mutations
Optogenetic switches for light-controlled gene expression in yeast
Extensive Recombination of a Yeast Diploid Hybrid through Meiotic Reversion
Natural variation in non-coding regions underlying phenotypic diversity in budding yeast
Powerful decomposition of complex traits in a diploid model
RIM15 antagonistic pleiotropy is responsible for differences in fermentation and stress response kinetics in budding yeast
ATG18 and FAB1 Are Involved in Dehydration Stress Tolerance in Saccharomyces cerevisiae
Concerted Evolution of Life Stage Performances Signals Recent Selection on Yeast Nitrogen Use
A High-Definition View of Functional Genetic Variation from Natural Yeast Genomes
Mapping Genetic Variants Underlying Differences in the Central Nitrogen Metabolism in Fermenter Yeasts
High-Resolution Mapping of Complex Traits with a Four-Parent Advanced Intercross Yeast Population
Identification of genes related to nitrogen uptake in wine strains of Saccharomyces cerevisiae
The Genetic Basis of Natural Variation in Oenological Traits in Saccharomyces cerevisiae
Cinnamic acid, ethanol and temperature interaction on coumarate decarboxylase activity and the relative expression of the putative cd gene in D. bruxellensis
Revealing the genetic structure of a trait by sequencing a population under selection
Genomic and phenotypic comparison between similar wine yeast strains of Saccharomyces cerevisiae from different geographic origins
Taqman real-time PCR for the detection and enumeration of Saccharomyces cerevisiae in wine
POLYMERASE CHAIN REACTION CONFIRMATORY METHOD FOR MICROBIOLOGICAL DETECTION OF BRETTANOMYCES BRUXELLENSIS IN WINES

Proyecto (14)

Genomic and transcriptional profiling of fermentative vigor in laboratory lager yeast hybrid
Combining synthetic biology approaches for the reversible and simultaneous transcriptional control of multiple metabolic genes in yeast
Exploiting the wild genetic diversity of Saccharomyces cerevisiae for wine production
A synthetic biology approach for functional characterization of genes acquired by Horizontal Gene Transfer (HGT) in yeasts
Adquisición de un sistema de control automatizado de biorreactores Biostat B, para realizar investigación orientada a la industria de alimentos nacional en la Universidad de Santiago de Chile
Control de propiedades biotecnológicas e industriales de levaduras mediante interruptores optogenéticos
Esfuerzo colaborativo internacional para la caracterización funcional de genes adquiridos por transferencia horizontal en levaduras
Instituto Milenio de Biología Integrativa (iBio)
A SYNTHETIC RED-LIGHT TOGGLE SWITCH TO CONTROL GENE EXPRESSION AND MODULATE CIRCADIAN REGULATION IN NEUROSPORA CRASSA.
Generating a very large yeast diploid population with sequenced genomes for complex traits analysis
Postdoctorado Becas Chile=> The Genetics Basis of Cancer Drugs Resistance in Yeast
DOCTORADO EN CIENCIAS M/MICROBIOLOGIA (CONJUNTO CON UCH)
Pasantía Doctoral Becas Chile=> Asociación entre fenotipos enológicos y el genotipo de cepas vínicas de Saccharomyces cerevisiae
DOCTORADO EN CIENCIAS M/MICROBIOLOGIA (CONJUNTO CON UCH)
38
Francisco Salinas

Profesor Asociado

Instituto de Bioquímica y Microbiolgía

Universidad Austral de Chile

Valdivia, Chile

18
Claudio Martinez

Profesor Titular

Departamento de Ciencia y Tecnología de Alimentos

Universidad de Santiago de Chile

Santiago, Chile

10
Francisco Cubillos

Investigador Asociado

Departamento de Biologia

Universidad de Santiago de Chile

Santiago, Chile

7
Eduardo Kessi

Investigador

Universidad de Santiago de Chile

Santiago, Chile

7
veronica garcia

academico

DECYTAL

Universidad de Santaigo

Estación central, Chile

6
MARIA GANGA

academico jornada completa

Departamento en Ciencia y Tecnologia de los Alimentos

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

5
Luis Larrondo

Associate Professor

Genetica Molecular y Microbiologia

Pontificia Universidad Catolica de Chile

Santiago, Chile

5
Jennifer Molinet

Postdoctorado

Departamento de Biología

Universidad de Santiago de Chile

Santiago, Chile

3
Veronica Delgado

Investigador postdoctoral

Genética Molecular y Microbiología

Instituto Milenio de Biología Integrativa (iBio)

Santiago, Chile

2
Manuel Villalobos

Profesor asistente

Ingeniería Informática

Universidad de Santiago de Chile

santiago, Chile

2
Angela Contreras

Academica Investigadora

Ciencias Agrarias y Forestales

Universidad Católica del Maule

Talca, Chile

2
Carlos Villarroel

Académico

Ciencias Forestales

Universidad Católica del Maule

Talca, Chile

2
Diego Ruiz

Asistente de Investigación

Instituto de Bioquímica

Universidad Austral de Chile

Valdivia, Chile

2
ULISES URZUA

Assistant Professor

ICBM

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Eduardo Agosin

Full Professor

Chemical and Bioprocess Engineering

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

1
Daniel Garrido

Associate Professor

Chemical and Bioprocess Engineering

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Matias Jara

Chief Executive Officer

Living Matter and Complex Systems

Cellter

Santiago, Chile

1
Pablo Villarreal

Investigador Postdoctoral

Departamento de Biología

Universidad de Santiago de Chile

Santiago, Chile

1
DINKA MANDAKOVIC

Assistant Professor

GEMA Center

Universidad Mayor

Santiago, Chile