Francisco-cubillos-riffo.jpg_thumb90

Francisco Alberto Cubillos Riffo

Investigador Asociado

Universidad de Santiago de Chile

Santiago, Chile

Líneas de Investigación


Genética de Poblaciones Genética Cuantitativa Bioinformática Microbiología Levaduras

Educación

  •  Genética, UNIVERSITY OF NOTTINGHAM. Reino Unido, 2010
  •  Ciencias, UNIVERSIDAD DE CHILE. Chile, 2008
  •  Ingeniero en Biotecnología Molecular, UNIV.COLUMBUS. Chile, 2007

Experiencia Académica

  •   Investigador Asociado Full Time

    UNIVERSIDAD DE SANTIAGO DE CHILE

    Santiago, Chile

    2013 - A la fecha

Experiencia Profesional

  •   Post-doc Full Time

    INRA Versailles

    Versailles, Francia

    2011 - 2013

Formación de Capital Humano


- Dirección de 30 tesis de pregrado
- Dirección de 10 tesis de postgrado
- Dirección de 8 Post-doctorados


Difusión y Transferencia


La difusión se ha realizado a través de
- Charla Nerd Nights
- Aparición en Futuro360 CNN
- TV Valdivia
- Emol
- Noticiario CHV
- Mega+ programa Tendencias
- Charla Festival 'Cambalache', USACH


Premios y Distinciones

  •   Mejor Alumno Licenciatura en Biotecnología Molecular

    UNIVERSIDAD DE CHILE

    Chile, 2006

    Reconocimiento al mejor promedio de notas de la generación 2006

  •   University Endowed Postgraduate Prize

    UNIVERSITY OF NOTTINGHAM

    Reino Unido, 2010

    Premio a los mejores 10 alumnos de post-grado en la Universidad de Nottingham

  •   Mejor Investigador Científico Joven - Grupo Bios

    SOCIEDAD DE BIOLOGIA DE CHILE

    Chile, 2022

    Seleccionado como Científico Joven 2022


 

Article (51)

<i>Nakazawaea atacamensis</i> f.a., sp. nov. a novel nonconventional fermentative ascomycetous yeast species from the Atacama Desert
An integrative taxonomy approach reveals Saccharomyces chiloensis sp. nov. as a newly discovered species from Coastal Patagonia
An Open One-Step RT-qPCR for SARS-CoV-2 detection
Climate change and population persistence in a hibernating marsupial
Domestication signatures in the non-conventional yeast <i>Lachancea cidri</i>
Taxogenomic analyses of<i> Starmerella</i><i> gilliamiae</i> f.a, sp. nov. and<i> Starmerella</i><i> monicapupoae</i> f.a., sp. nov., two novel species isolated from plant substrates and insects
Wild Patagonian yeast improve the evolutionary potential of novel interspecific hybrid strains for lager brewing
Addition of<i> Saccharomyces</i><i> eubayanus</i> to SCOBY fermentations modulates the chemical and volatile compound profiles in kombucha
Modeling heterothermic fitness landscapes in a marsupial hibernator using changes in body composition
A Saccharomyces eubayanus haploid resource for research studies
Genetic Background Matters: Population-Based Studies in Model Organisms for Translational Research
Late Pleistocene-dated divergence between South Hemisphere populations of the non-conventional yeast L. cidri
Natural Variation in Diauxic Shift between Patagonian <i>Saccharomyces eubayanus</i> Strains
Rapid selection response to ethanol in Saccharomyces eubayanus emulates the domestication process under brewing conditions
The evolution, evolvability and engineering of gene regulatory DNA
Anthocyanins from Aristotelia chilensis Prevent Olanzapine-Induced Hepatic-Lipid Accumulation but Not Insulin Resistance in Skeletal Muscle Cells
An Out-of-Patagonia migration explains the worldwide diversity and distribution of Saccharomyces eubayanus lineages
Fungal Diversity Analysis of Grape Musts from Central Valley-Chile and Characterization of Potential New Starter Cultures
Into the wild: new yeast genomes from natural environments and new tools for their analysis
Molecular profiling of beer wort fermentation diversity across natural Saccharomyces eubayanus isolates
Performance, genomic rearrangements, and signatures of adaptive evolution: Lessons from fermentative yeasts
Transcriptional Activity and Protein Levels of Horizontally Acquired Genes in Yeast Reveal Hallmarks of Adaptation to Fermentative Environments
Volatile Compound Screening Using HS-SPME-GC/MS on Saccharomyces eubayanus Strains under Low-Temperature Pilsner Wort Fermentation
Wild Yeast for the Future: Exploring the Use of Wild Strains for Wine and Beer Fermentation
Distinct Transcriptional Changes in Response to Patulin Underlie Toxin Biosorption Differences in Saccharomyces cerevisiae
Genetic variants of TORC1 signaling pathway affect nitrogen consumption in Saccharomyces cerevisiae during alcoholic fermentation
Adaptability of the Saccharomyces cerevisiae yeasts to wine fermentation conditions relies on their strong ability to consume nitrogen
GPD1 and ADH3 Natural Variants Underlie Glycerol Yield Differences in Wine Fermentation
Genetic basis of mycotoxin susceptibility differences between budding yeast isolates
Genomics Perspectives on Metabolism, Survival Strategies, and Biotechnological Applications of Brettanomyces bruxellensis LAMAP2480.
Identification of Nitrogen Consumption Genetic Variants in Yeast Through QTL Mapping and Bulk Segregant RNA-Seq Analyses
Natural gene expression variation studies in yeast
Exploiting budding yeast natural variation for industrial processes
Natural variation in non-coding regions underlying phenotypic diversity in budding yeast
RIM15 antagonistic pleiotropy is responsible for differences in fermentation and stress response kinetics in budding yeast
Draft genome sequence and transcriptome analysis of the wine spoilage yeast Dekkera bruxellensis LAMAP2480 provides insights into genetic diversity, metabolism and survival
Extensive cis-Regulatory Variation Robust to Environmental Perturbation in Arabidopsis
Mapping Genetic Variants Underlying Differences in the Central Nitrogen Metabolism in Fermenter Yeasts
SHOOT GROWTH1 maintains arabidopsis epigenomes by regulating IBM1
High quality de novo sequencing and assembly of the Saccharomyces arboricolus genome
High-Resolution Mapping of Complex Traits with a Four-Parent Advanced Intercross Yeast Population
Expression variation in connected recombinant populations of Arabidopsis thaliana highlights distinct transcriptome architectures
Lessons from eQTL mapping studies: non-coding regions and their role behind natural phenotypic variation in plants
Life History Shapes Trait Heredity by Accumulation of Loss-of-Function Alleles in Yeast
The Genetic Basis of Natural Variation in Oenological Traits in Saccharomyces cerevisiae
Assessing the complex architecture of polygenic traits in diverged yeast populations
Revealing the genetic structure of a trait by sequencing a population under selection
Trait Variation in Yeast Is Defined by Population History
Generation of a large set of genetically tractable haploid and diploid Saccharomyces  strains
Segregating YKU80 and TLC1 Alleles Underlying Natural Variation in Telomere Properties in Wild Yeast
Self-fertilization is the main sexual reproduction mechanism in native wine yeast populations

Proyecto (21)

Producción de whisky utilizando componentes locales chilenos
Genomic and transcriptional profiling of fermentative vigor in laboratory lager yeast hybrids
Genomic and physiological Characterization of ethanol-&#8208;producing yeast populations From Patagonia
Identification of the molecular bases of adaptation to brewing conditions of native S. eubayanus
Aislamiento y caracterización de una cepa de levadura nativa para la cervecería artesanal de la Región de Los Ríos
Decoding the genomic and phenomic complexity of the cryotolerant yeast Saccharomyces eubayanus
Millennium Institute for Integrative Systems and Synthetic Biology
Biochemical and molecular responses disclose mechanisms of Antarctic macroalgae to thrive under Climate Change
GENETIC VARIATION IN TRANSCRIPTION FACTOR BINDING SITES UNDERLYING NITROGEN ASSIMILATION DIFFERENCES IN YEAST ISOLATES
Millennium Nucleus for Fungal Integrative and Synthetic Biology
Applied yeast genetics for food products
Biochemical and molecular responses disclose mechanisms of Antarctic macroalgae to thrive under Climate Change
IDENTIFICATION OF NATURAL GENETIC VARIANTS UNDERLYING NITROGEN ASSIMILATION DIVERSITY IN YEAST
QUANTITATIVE GENETIC ANALYSIS OF THE RESPONSE TO MYCOTOXINS IN YEAST
Establecimiento de sistemas sustentables para el control del proceso de producción de Vino Pajarete de la Provincia del Huasco, para fortalecer su identidad local
Estudio de las variantes regulatorias que subyacen la diversidad natural en Saccharomyces cerevisiae
Identification of allelic variants underlying Nitrogen Metabolism in yeast through an integrative BS-RNA seq approach
Decoding the complexity of quantitative natural variation in Arabidopsis thaliana
Exploiting natural genetic variation to map QTLs of telomere properties in Yeast=> Length silencing ageing and senescence
Telomeres and subtelomeres in yeast
GENOMICA ESTRUCTURAL EN AISLADOS NATIVOS DE LEVADURAS DE INTERES ENOLOGICO

Review (1)

Bioprospecting for brewers: Exploiting natural diversity for naturally diverse beers
54
Francisco Cubillos

Investigador Asociado

Departamento de Biologia

Universidad de Santiago de Chile

Santiago, Chile

12
Claudio Martinez

Profesor Titular

Departamento de Ciencia y Tecnología de Alimentos

Universidad de Santiago de Chile

Santiago, Chile

10
Francisco Salinas

Profesor Asociado

Instituto de Bioquímica y Microbiolgía

Universidad Austral de Chile

Valdivia, Chile

9
Carlos Villarroel

Académico

Ciencias Forestales

Universidad Católica del Maule

Talca, Chile

8
Verónica García

academico

DECYTAL

Universidad de Santaigo

Estación central, Chile

6
Jennifer Molinet

Postdoctorado

Departamento de Biología

Universidad de Santiago de Chile

Santiago, Chile

3
Luis Larrondo

Associate Professor

Genetica Molecular y Microbiologia

Pontificia Universidad Catolica de Chile

Santiago, Chile

3
MARIA GANGA

academico jornada completa

Departamento en Ciencia y Tecnologia de los Alimentos

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

2
Rodrigo Gutierrez

Full Professor

Molecular Genetics & Microbiology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

2
Tomas Peña

Candidato Doctor en Biotecnología

Departamento de Biología

Laboratorio de Genética Molecular, Universidad de Santiago de Chile

Santiago, Chile

2
Pablo Villarreal

Investigador Postdoctoral

Departamento de Biología

Universidad de Santiago de Chile

Santiago, Chile

2
Eduardo Kessi

Investigador

Universidad de Santiago de Chile

Santiago, Chile

1
Veronica Delgado

Investigador postdoctoral

Genética Molecular y Microbiología

Instituto Milenio de Biología Integrativa (iBio)

Santiago, Chile

1
Rodrigo Troncoso

Associate Professor

Instituto de Nutrición y Tecnología de los Alimentos

Santiago, Chile

1
Claudio Acuña

Profesosr Asociado

Biología

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

1
Matias Jara

Chief Executive Officer

Living Matter and Complex Systems

Cellter

Santiago, Chile

1
Paz Tapia

Ingeniera en Bioinformatica

Laboratorio Biomedico

Instituto de Salud Publica

Santiago, Chile

1
Luis Milla

Profesor Asistente

Escuela de Medicina

Universidad de Santiago

Santiago, Chile

1
Macarena Las Heras

Investigadora postdoctoral

Facultad de Química y Biología

Universidad de Santiago de Chile

Santiago, Chile

1
Pablo Saenz

Associate Professor

Facultad de Ciencias

Universidad Austral de Chile

Valdivia, Chile

1
Camila Calfío

Investigador PhD/Jefe de Proyectos

Corp. Centro Internacional de Biomedicina ICC

Santiago, Chile

1
Felipe Muñoz

Investigador Postdoctoral

Biología

USACH

Santiago, Chile

1
Liliana Godoy

Profesor Asociado

Fruticultura y Enología

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Evelyn Silva

Directora Ejecutiva

Vicerrectoria

Universidad Mayor de Chile

Santiago, Chile

1
Francisca Díaz

Investigadora

Instituto de Geografía

Pontificia Universidad Católica de Valparaíso

VALPARAISO, Chile

1
Jorge Valdes

PROFESOR ASOCIADO

CENTRO DE BIOINFORMÁTICA Y BIOLOGÍA INTEGRATIVA

Universidad Andrés Bello

Santiago, Chile

1
Paulo Moreno

Investigador residente

Centro de Investigación en Ecosistemas de la Patagonia

Coyhaique, Chile

1
Catalina Ibarra

Investigadora

Genética Molecular y Microbiología

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Sylvain Faugeron

Profesor Asociado

ecologia

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile