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César Antonio Echeverría Echeverría

DIRECTOR DE INVESTIGACIÓN

Universidad de Atacama

COPIAPO, Chile

Líneas de Investigación


FISIOPATOLOGÍA; BIOLOGÍA CELULAR; BIOLOGÍA MOLECULAR, NANOMEDICINA

Educación

  •  BIOQUÍMICO , UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 2004
  •  Fisiopatología, UNIVERSIDAD ANDRES BELLO. Chile, 2013

Experiencia Académica

  •   ASISTENTE ACADÉMICO Part Time

    UNIVERSIDAD ANDRES BELLO

    2009 - 2011

  •   PROFESOR ASOCIADO Full Time

    UNIVERSIDAD BERNARDO O'HIGGINS

    Santiago, Chile

    2014 - 2018

  •   Director de Investigación Full Time

    UNIVERSIDAD DE ATACAMA

    Medicina

    COPIAPO, Chile

    2018 - A la fecha

Experiencia Profesional

  •   Postdoc

    UNIVERSIDAD DE CHILE

    Chile

    2014 - 2017

  •   DIRECTOR DEL CENTRO DE INVESTIGACIÓN DE MINERALES ESTRATEGICOS Full Time

    UNIVERSIDAD BERNARDO O´HIGGINS

    Chile

    2014 - 2018

  •   Director de Investigación Full Time

    Universidad de Atacama

    COPIAPO, Chile

    2018 - A la fecha


 

Article (42)

A new subtle and integrated detector to sense Hg2+ ions: A vision towards its applicability on water samples and live cells
Bidentate acylthiourea ligand anchored Pd-PPh3 complexes with biomolecular binding, cytotoxic, antioxidant and antihemolytic properties
Design and synthesis of heterocyclic azole based bioactive compounds: Molecular structures, quantum simulation, and mechanistic studies through docking as multi-target inhibitors of SARS-CoV-2 and cytotoxicity
Design of a dual responsive receptor with oxochromane hydrazide moiety to monitor toxic Hg2+ and Cd2+ ions: Usage on real samples and live cells
Synthesis, structural, DNA/protein binding and cytotoxic studies of copper (I) proportional to-diimine hydrazone complexes
Targeting Histone Deacetylases: Opportunities for Cancer Treatment and Chemoprevention
Effect of morphology and (Sn, Cr) doping on in vitro antiproliferation properties of hydrothermally synthesized 1D GaOOH nanostructures
Effect of new Pd(II)-aroylthiourea complex on pancreatic cancer cells
Effective inhibition of insulin amyloid fibril aggregation by nickel(II) complexes containing heterocyclic thiosemicarbazones
Impact of aliphatic acyl and aromatic thioamide substituents on the anticancer activity of Ru(II)-p-cymene complexes with acylthiourea ligands-in vitro and in vivo studies
Synthesis, cytotoxicity and docking studies (with SARS-CoV-2) of water-soluble binuclear Ru-p-cymene complex holding indole thiosemicarbazone ligand
Endothelial dysfunction in pregnancy metabolic disorders
Erythroid Differentiation and Heme Biosynthesis Are Dependent on a Shift in the Balance of Mitochondrial Fusion and Fission Dynamics
TRPM7 mediates kidney injury, endothelial hyperpermeability and mortality during endotoxemia
Endotoxemia-induced endothelial fibrosis inhibition improves hypotension, tachycardia, multiple organ dysfunction syndrome, cytokine response, oxidative stress, and survival
Imogolite Synthetized in Presence of As(III) Induces Low Cell Toxicity and Hemolysis, in Vitro, Potential Stabilization of Arsenite Present in Aqueous Systems
OxHDL controls LOX-1 expression and plasma membrane localization through a mechanism dependent on NOX/ROS/NF-kappa B pathway on endothelial cells
TRPM4 channel is involved in regulating epithelial to mesenchymal transition, migration, and invasion of prostate cancer cell lines
Preventive Leptin Administration Protects Against Sepsis Through Improving Hypotension, Tachycardia, Oxidative Stress Burst, Multiple Organ Dysfunction, and Increasing Survival
The cluster [Re6Se8I6](3-) penetrates biological membranes: drug-like properties for CNS tumor treatment and diagnosis
Transient Receptor Potential Vanilloid 1 Expression Mediates Capsaicin-Induced Cell Death
TRPM4 regulates Akt/GSK3-beta activity and enhances beta-catenin signaling and cell proliferation in prostate cancer cells
Cytokine-Mediated Pathways That Determine Endothelial Fibrosis under Inflammatory Conditions
Endothelial-to-mesenchymal transition: Cytokine-mediated pathways that determine endothelial fibrosis under inflammatory conditions
Human Peritoneal Mesothelial Cell Death Induced by High-Glucose Hypertonic Solution Involves Ca2+ and Na+ Ions and Oxidative Stress with the Participation of PKC/NOX2 and PI3K/Akt Pathways
The [Mo6Cl14](2-) Cluster is Biologically Secure and Has Anti-Rotavirus Activity In Vitro
Chalcone-Induced Apoptosis through Caspase-Dependent Intrinsic Pathways in Human Hepatocellular Carcinoma Cells
INTERACTION OF CHALCONES WITH CT-DNA BY SPECTROPHOTOMETRIC ANALYSIS AND THEORETICALSIMULATIONS
Medicinal Organometallic Compounds with Anti-Chagasic Activity
Medicinal organometallic compounds with anti-chagasic activity
The Characterization of Anti-T. Cruzi Activity Relationships between Ferrocenyl, Cyrhetrenyl Complexes and ROS Release
Suppression of transient receptor potential melastatin 4 expression promotes conversion of endothelial cells into fibroblasts via transforming growth factor/activin receptor-like kinase 5 pathway
Endotoxin Induces Fibrosis in Vascular Endothelial Cells through a Mechanism Dependent on Transient Receptor Protein Melastatin 7 Activity
Endotoxin-induced endothelial fibrosis is dependent on the expression of TGF-β1 and TGF-β2
Endotoxin-induced vascular endothelial cell migration is dependent on TLR4/NF-kappa B pathway, NAD(P)H oxidase activation, and transient receptor potential melastatin 7 calcium channel activity
Oxidative stress mediates the conversion of endothelial cells into myofibroblasts via a TGF-beta 1 and TGF-beta 2-dependent pathway
Lipopolysaccharide induces a fibrotic-like phenotype in endothelial cells
Release of gliotransmitters through astroglial connexin 43 hemichannels is necessary for fear memory consolidation in the basolateral amygdala
The paramagnetic and luminescent [Re6Se8I6](3-) cluster. Its potential use as an antitumoral and biomarker agent
Increased Expression of the Transient Receptor Potential Melastatin 7 Channel Is Critically Involved in Lipopolysaccharide-Induced Reactive Oxygen Species-Mediated Neuronal Death
Transient receptor potential melastatin 4 inhibition prevents lipopolysaccharide-induced endothelial cell death
Structural Antitumoral Activity Relationships of Synthetic Chalcones

Abstract (1)

Vascular endothelial fibrosis induced by endotoxin: characteristics, mechanism and therapeutic perspectives

Errata (1)

Endotoxin-Induced Endothelial Fibrosis Is Dependent on Expression of Transforming Growth Factors beta 1 and beta 2 (vol 82, pg 3678, 2014)

Proyecto (4)

DIFFERENTIAL EXPRESSION OF TRPM4 REGULATES THE REPRESSOR TRANSCRIPTION FACTORS EXPRESSION-MEDIATED SWITCH BETWEEN EMT-MET FOR PROGRESSION OF HUMAN UROTHELIAL BLADDER CARCINOMA
El lipopolisacarido induce transicion epitelio-mesequimal del urotelio de la vejiga
EL LIPOPOLISACARIDO INDUCE TRANSICION EPITELIO-MESEQUIMAL DEL UROTELIO DE LA VEJIGA.
Participación de canales iónicos TRPM en la fibrosis endotelial inducida por lipopolisacárido
41
César Echeverría

DIRECTOR DE INVESTIGACIÓN

Medicina

Universidad de Atacama

COPIAPO, Chile

16
Felipe Simon

Profesor Titular

Department of Biological Sciences

UNIVERSIDAD ANDRES BELLO FAC DE CS BIOLOGICAS, DPTO DE CS BIOLOGICAS

Santiago, Chile

9
Ricardo Armisen

Associate Professor

Centro de Genética y Genómica

Universidad del Desarrollo

Santiago, Chile

9
Claudio Cabello

Full Professor

Ciencias Biologicas

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

8
Rodrigo Ramírez

Consultor

Asesorias CUBO

Santiago, Chile

7
Haribabu J

Fondecyt-Postdoctoral Research Fellow

Faculty of Medicine

Universidad de Atacama

Copiapo, Chile

6
Diego Varela

Profesor Asociado

Fisiología y Biofísica

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

4
Alvaro Becerra

Profesor Asociado

Ciencias Químico y Biológicas

Universidad Bernardo O'Higgins

Santiago, Chile

3
Pablo Tapia

Jefe Técnico Unidad de Paciente Crítico (UPC)

Unidad Paciente Critico (UPC)

Hospital Clinico Metropolitano La Florida

Santiago, Chile

2
Alvaro Elorza

FULL PROFESSOR

INSTITUTE OF BIOMEDICAL SCIENCES

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

2
Edgardo Rojas

Académico e Investigador

Ciencias Químicas y Biológicas

Universidad Bernardo OHiggins

Santiago, Chile

2
Ricardo Fernández

Associate Professor

Salud

Universidad de Los Lagos

Osorno, Chile

2
Andres Stutzin

Full Professor

ICBM

FACULTAD DE MEDICINA UNIVERSIDAD DE CHILE

Santiago, Chile

2
Omar Porras

Assistant professor

Lab. Biología Celular

UNIVERSIDAD DE CHILE

Santiago, Chile

2
Ricardo Fernandez

Profesor Asociado A

Salud

Universidad de Los Lagos

Osorno, Chile

2
Jimmy Stehberg

Associate Professor

Biological Sciences

UNIVERSIDAD ANDRÉS BELLO

SANTIAGO, Chile

1
Pablo Báez

Investigador Postdoctoral

Centro de Informática Médica y Telemedicina

Universidad de Chile

Santiago, Chile

1
Pablo Olivero

Profesor Adjunto

Patologia y Fisiologia

Universidad de Valparaiso

Viña del Mar, Chile

1
Ivanny Marchant

ESCUELA DE MEDICINA UNIVERSIDAD DE VALPARAISO

Valparaiso, Chile

1
Vincenzo Borgna

Investigador

Inmuno-Oncología

FUNDACION CIENCIA VIDA

Santiago, Chile

1
Luis Michea

PROFESOR ASOCIADO

PROGRAMA FISIOLOGIA Y BIOFISICA

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Cesar Morales

Associate Professor

Universidad Bernardo O'Higgins

Santiago, Chile

1
Natalia Muñoz

Estudiante de Doctorado y Jefe Alterno_Proyecto COPEC-UC R772

Genética Molecular y Microbiología

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Claudia Riedel

Full Professor

Life Sciences

Universidad Andres Bello

Santiago, Chile

1
Claudio Cordova

Investigador asistente

Medicina

Universidad de Valparaíso

Valparaíso, Chile

1
Ramiro Arratia

DIRECTOR DOCTORADO

CIENCIAS QUIMICAS

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

1
Eduardo Schott

Profesor Asociado

Departamento de Química Inorgánica

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Juan Santibáñez

Professor of Research

Molecular Oncology

Institute for Medical Research

Belgrade, Serbia

1
Belen Rodriguez

Jefa de Calidad

Departamento de Patología

Universidad de Valparaíso

Viña del Mar, Chile

1
Katherine Marcelain

Profesora Asociada

Oncología Básico Clínica

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA

Santiago, Chile

1
Oscar Cerda

Associate Professor

Molecular and Cellular Biology

Universidad de Chile

Santiago, Chile

1
Monica Caceres

Profesor asociado

Instituto de ciencias biomedicas

Universidad de Chile

Santiago, Chile

1
Luis Velasquez

Director and Full Professor

Medicine

Universidad SEK

Santiago, Chile

1
Claudio Perez

Profesor Asistente

Departamento de Ciencias Fisiológicas

Pontificia Universidad Catolica de Chile

Santiago, Chile

1
Julio Tapia

Profesor Asociado

Oncologia Basico Clinica

Universidad de Chile

Santiago, Chile

1
Leonor Alvarado

Independiente

Particular

Santiago, Chile

1
Xavier Figueroa

Associate Professor

Departamento de Fisiologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
carlo lozano

Profesor asociado

Facultad de Medicina

Universidad de Valparaíso

Valparaíso, Chile

1
Ricardo Ramírez

Coordinador académico

Universidad Andrés Bello

Viña del Mar, Chile

1
Alvaro Muñoz

Full time professor

Dirección de Investigación y Postgrado

Universidad Autónoma de Chile

Santiago, Chile

1
Juan Saez

Professor

Instituto de Neurociencias

Universidad de Valparaiso

Valparaíso, Chile

1
Mauricio Retamal

Associate Professor

Centro de Fisiología Celular e Integrativa

Universidad del Desarrollo

Santiago, Chile

1
Juan Sáez

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Juan Orellana

Associate Professor

Departamento de Neurología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Alvaro Muñoz

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

1
Alejandro Vallejos

Asistente de Investigación

Ciencias de la Vida

Laboratorio de Fisiopatología Integrativa

Santiago, Chile

1
felipe velasquez

Estudiante de doctorado

Virologia

Universidad de Chile

Santiago, Chile

1
Karen Manquián

Adjunto 1

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

1
Claudio Cappelli

Technical Laboratory Manager

Facultad de Medicina

Universidad Austral de Chile

Valdivia, Chile

1
Fernando Valiente

Profesor Asociado

ICBM

Universidad de Chile

Santiago, Chile