Man

Luis Alberto Velasquez Cumplido

Director and Full Professor

Universidad SEK

Santiago, Chile

Líneas de Investigación


Biomedicine, pathogenic host response, bionanotechnology, toxicology and pharmacologyl and cellular Biology,

Educación

  •  biological Sciences, Physiological Sciences mention, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1997

Experiencia Académica

  •   Full Professor Full Time

    UNIVERSIDAD DE SANTIAGO DE CHILE

    Chemistry and Biology

    Santiago, Chile

    1998 - 2011

  •   Full professor and Director Center for integrative Medicine and Innovative Science Full Time

    Universidad Andrés Bello

    Medicina

    Santiago, Chile

    2012 - 2018

  •   Director Full Time

    Universidad SEK

    Ciencias de la Salud

    Santiago, Chile

    2018 - A la fecha

Experiencia Profesional

  •   Full Professor Full Time

    Universidad Andrés Bello

    Santiago, Chile

    2012 - 2018

Formación de Capital Humano


Tutor of Gabriela San Martin, M.Sc. Biochemistry, 2014 (in progress)
Tutor of Guillermo Carrasco, M.Sc. Biochemistry, 2014 (in progress)
Tutor of Andrea Aravena, Pharmaceutical Chemical, 2013
Co-Tutor of Natalia Juica. Biochemistry, 2013
Tutor of Cristian Vilos, PhD. in Biotechnology, 2012
Co-Tutor of Francisco Morales, Biochemistry, 2012
Tutor, Jocelyn Rocco, Biochemistry, 2010
Tutor, Katherine Garcia, Biochemistry, 2005
Tutor, Macarena Vargas, Biochemistry, 2005
Tutor, Paz Reyes, Biochemistry, 2004
Tutor, Priscilla Morales, Biochemistry, 2002



 

Article (57)

Experimental and theoretical structural/spectroscopical correlation of enterobactin and catecholamide
IR and NMR spectroscopic correlation of enterobactin by DFT
Effects of Liposomes Contained in Thermosensitive Hydrogels as Biomaterials Useful in Neural Tissue Engineering
Intracellular trafficking and cellular uptake mechanism of PHBV nanoparticles for targeted delivery in epithelial cell lines.
Neisseria gonorrhoeae Challenge Increases Matrix Metalloproteinase-8 Expression in Fallopian Tube Explants
Role of the spinal TrkB-NMDA receptor link in the BDNF-induced long-lasting mechanical hyperalgesia in the rat=> A behavioural study.
Chocolate, Air Pollution and Children's Neuroprotection=> What Cognition Tools should be at Hand to Evaluate Interventions?
Effect of single post-ovulatory administration of mifepristone (RU486) on transcript profile during the receptive period in human endometrium
Effect of Terminal Groups of Dendrimers in the Complexation with Antisense Oligonucleotides and Cell Uptake
Increases in reactive oxygen species enhance vascular endothelial cell migration through a mechanism dependent on the transient receptor potential melastatin 4 ion channel.
Increases in reactive oxygen species enhance vascular endothelial cell migration through a mechanism dependent on the transient receptor potential melastatin 4 ion channel
Multifunctional polymeric nanoparticles doubly loaded with SPION and ceftiofur retain their physical and biological properties
Physicochemical assessment of Dextran-g-Poly (epsilon-caprolactone) micellar nanoaggregates as drug nanocarriers
Preclinical Development and In Vivo Efficacy of Ceftiofur-PLGA Microparticles
Development and characterization of ten polymorphic microsatellites isolated from the scallop Argopecten purpuratus
Endotoxin Induces Fibrosis in Vascular Endothelial Cells through a Mechanism Dependent on Transient Receptor Protein Melastatin 7 Activity
Evaluation of ceftiofur-PHBV microparticles in rats
Temporal and spatial regulation of cAMP signaling in disease: role of cyclic nucleotide phosphodiesterases
In vivo biocompatibility of the PLGA microparticles in parotid gland
Paclitaxel-PHBV nanoparticles and their toxicity to endometrial and primary ovarian cancer cells
Paclitaxel-PHBV nanoparticles and their toxicity to endometrial and primary ovarian cancer cells
Superparamagnetic Poly (3-hydroxybutyrate-co-3 hydroxyvalerate) (PHBV) nanoparticles for biomedical applications
Tumour necrosis factor-alpha is the signal induced by mating to shutdown a 2-methoxyestradiol nongenomic action necessary to accelerate oviductal egg transport in the rat
Ceftiofur-loaded PHBV microparticles: A potential formulation for a long-acting antibiotic to treat animal infections
Differential expression of extracellular matrix components in the Fallopian tubes throughout the menstrual cycle
Effect of single post-ovulatory administration of levonorgestrel on gene expression profile during the receptive period of the human endometrium
Mycoplasmateceae species are not found in Fallopian tubes of women with tubo-peritoneal infertility
Mycoplasmateceae species are not found in Fallopian tubes of women with tubo-peritoneal infertility
Neisseria gonorrhoeae Pilus Attenuates Cytokine Response of Human Fallopian Tube Explants
The Case Against Template Informed Consent Procedures in Biomedical Research: Heterogeneity in Health Literacy in Chile
The case against template informed consent procedures in biomedical research: Heterogeneity in health literacy in Chile [La heterogeneidad del alfabetismo en salud y el consentimiento informado en Chile]
Morphometric and Histopathologic Changes in Skeletal Muscle Induced for Injectable PLGA Microparticles
Morphometric and histopathologic changes in skeletal muscle induced for injectable PLGA microparticles Cambios morfométricos e histopatológicos en el músculo esquelético inducidos por microparticulas de PLGA inyectables
Participation of the oviductal s100 calcium binding protein G in the genomic effect of estradiol that accelerates oviductal embryo transport in mated rats
Proprotein Convertase 5/6 Is Critical for Embryo Implantation in Women: Regulating Receptivity by Cleaving EBP50, Modulating Ezrin Binding, and Membrane-Cytoskeletal Interactions
A non-genomic signaling pathway shut down by mating changes the estradiol-induced gene expression profile in the rat oviduct
Nitric oxide is not involved in Neisseria gonorrhoeae induced cellular damage of human Fallopian tubes in vitro
Nitric oxide is not involved in Neisseria gonorrhoeae-induced cellular damage of human Fallopian tubes in vitro
Mating changes the subcellular distribution and the functionality of estrogen receptors in the rat oviduct
Differences in the endometrial transcript profile during the receptive period between women who were refractory to implantation and those who achieved pregnancy
Embryotoxicity of serum from women smoking cocaine base paste (CBP)
Embryotoxicity of serum from women smoking cocaine base paste (CBP)
Apoptosis related genes expressed in cultured Fallopian tube epithelial cells infected in vitro with Neisseria gonorrhoeae
Catechol-O-methyltransferase and methoxyestradiols participate in the intraoviductal nongenomic pathway through which estradiol accelerates egg transport in cycling rats
Genital Sensory Stimulation Shifts Estradiol Intraoviductal Signaling from Nongenomic to Genomic Pathways, Independently from Prolactin Surges
Genital Sensory Stimulation Shifts Estradiol Intraoviductal Signaling from Nongenomic to Genomic Pathways, Independently from Prolactin Surges
Deficient expression of monoamine oxidase A in the endometrium is associated with implantation failure in women participating as recipients in oocyte donation
Infection of human Fallopian tube epithelial cells with Neisseria gonorrhoeae protects cells from tumor necrosis factor alpha-induced apptosis
Proenkephalin A and the ?-aminobutyric acid A receptor ? subunit: expression, localization, and dynamic changes in human secretory endometrium
Fas ligand in the uterus of the non-pregnant mouse induces apoptosis of CD4+T cells
Sperm binding to oviductal epithelial cells in the rat: Role of sialic acid residues on the epithelial surface and sialic acid-binding sites on the sperm surface
Expression of proinflammatory cytokines and receptors by human fallopian tubes in organ culture following challenge with Neisseria gonorrhoeae
A segment and epithelium specific messenger ribonucleic acid fragment up-regulated by estradiol in the rat oviduct
Increased adhesiveness and internalization of Neisseria gonorrhoeae and changes in the expression of epithelial gonococcal receptors in the Fallopian tube of copper T and Norplant (R) users
PAF receptor and PAF acetylhydrolase expression in the endosalpinx of the human Fallopian tube: possible role of embryo-derived PAF in the control of embryo transport to the uterus
Expression of platelet-activating factor receptor in the hamster oviduct: Localization to the endosalpinx
POSSIBLE ROLE OF PLATELET-ACTIVATING FACTOR IN EMBRYONIC SIGNALING DURING OVIDUCTAL TRANSPORT IN THE HAMSTER

Abstract (8)

Combining chemotherapy and targeted therapies against resistance and recurrence in ovarian cancer
TNF-Alpha and TGF-Beta Signaling Cascades are Associated with the Changes in the Mode of Action of Estradiol in the Rat Oviduct
Effect of levonorgestrel on mRNA transcript levels in the human endometrium during the window of implantation
Expression of complement component inhibitors is increased in the endometrium during the receptive period and decreased in infertile women with implantation failure
Searching genes involved in human endometrial infertility
Estradiol-regulated genes in the rat oviduct: Hunting through bioinformatics.
In vitro interaction between Neisseria gonorrhoeae and the oviductal epithelium from users of copper-T intrauterine devices or Norplant (R) subdermal implants
Platelet-activating factor receptor expression in the endosalpinx of the human fallopian tube.

Comentario (1)

La Heterogeneidad del Alfabetismo en Salud y el Consentimiento Informado en Chile

EditorialMaterial (1)

IgA in the lumen of the human oviduct is not related to the menstrual cycle but increases during local inflammation

Patent (8)

Controlled release system including a gas or volatile encapsulated in a polymeric support and a matrix system, a method of preparing the system, and their use
COMPOSICION VETERINARIA INYECTABLE DE LIBERACION PROLONGADA DE CEFTIOFUR O FLORFENICOL QUE COMPRENDE MICROPARTICULAS DE ACIDO POLILACTICO-GLICOLICO (PLGA) Y PROCEDIMIENTO DE PREPARACION DE LA MISMA.
COMPOSICION VETERINARIA INYECTABLE DE LIBERACION PROLONGADA DE CEFTIOFUR O FLORFENICOL, BASADA EN MICROPARTICULAS DE POLI-3-HIDROXIBUTIRATO CO-3-HIDROXIVALERATO (PHBV) Y PROCEDIMIENTO DE PREPARACION DE LA MISMA.
Controlled release system comprising a gas or volatile encapsulated in a polymeric support and matrix system; method of preparation said system, and their use applied to agribusiness, forestry, pharmaceuticals, cosmetics among others.
METODO PARA INCREMENTAR LA EFICIENCIA METABOLICA O TASA DE CONVERSION BIOLOGICA DE SALMONIDOS EN CONDICIONES DE CULTIVO INTENSIVO QUE COMPRENDE ALIMENTAR CON UNA COMBINACION O MEZCLAS DE POLISACARIDOS PROVENIENTES DE MACROCYSTIS PYRIPHERA, SARCOTHALIA CRISPATA, Y GIGARTINA SKOTTSBERGII.
MÉTODO PARA INCREMENTAR EL CRECIMIENTO DE SALMÓNIDOS MEDIANTE LA UTILIZACIÓN DE POLISACÁRIDOS.
MÉTODO PARA LA DISMINUCIÓN DE LA ENDOGAMIA EN SISTEMAS DE CULTIVOS DE BIVALVOS.
NANOPARTÍCULAS CON POLÍMERO BIODEGRADABLE Y BIOCOMPATIBLE PLGA CARGADAS CON EL FÁRMACO DE USO HUMANO PENTOXIFILINA.

Proyecto (12)

Diseño, síntesis y ensayos biológicos funcionales de dendrimedos modificados con aminoácidos para el bloqueo de la adhesión o internalización de infecciones de transmisión sexual.
"Diseño, sintesis y ensayos biológicos funcionales de dendrímeros modificados con aminoácidos para el bloqueo de la adhesión o internalización de infecciones de transmisión sexual".
Desarrollo de aplicaciones basadas en nanotecnología, materiales avanzados, energía y sostenibilidad para sectores industriales, la formación de capital humano avanzado y la transferencia de tecnología y conocimiento a la industria y a la sociedad
Proyecto Gas en polvo, una nueva herramienta nano microtecnológica para controlar maduración, senescencia y pudriciones en frutos de exportación en postcosecha
THE ROLE OF EXTRACELLULAR MATRIX-ASSOCIATED PROTEINS DURING IN VITRO FALLOPIAN TUBE INFECTION BY NEISSERIA GONORRHOEA
SIGNALING CASCADES ELUCITADED BY TNF-ALPHA TO SHUT DOWN AN ESTRADIOL NON-GENOMIC PATHWAY IN OVIDUCTAL EPITHELIAL CELLS
CAMBIOS CELULARES Y MOLECULARES DE LA MATRIZ EXTRACELULAR DURANTE EL CICLO MENSTRUAL Y SU PAPEL EN LA INFECCION IN VITRO DE EXPLANTES DE TROMPA DE FALOPIO CON NEISSERIA GONORROHEAE.
MIMIC OF BONE FRACTURE AND CELLULAR INTERACTION WITH A LOCALIZED STRESS DISTRIBUTION
MECANISMOS CELULARES Y MOLECULARES ACTIVADOS POR EL COITO IMPLICADOS EN EL SILENCIAMIENTO DE LA VIA DE SEÑALIZACION NO-GENOMICA DEL ESTRADIOL EN EL OVIDUCTO
CARACTERIZACION MOLECULAR DE LA RESPUESTA DEL ENDOSALPIX DE LA TROMPA DE FALOPIO INFECTADO IN VITRO CON NEISSERIA GONORRHOEAE
IDENTIFICACION DE LOS GENES QUE RESPONDEN A ESTRADIOL EN CELULAS OVIDUCTALES Y QUE ESTAN INVOLUCRADOS EN LA REGULACION DEL TRANSPORTE OVULAR.
CONTROL EMBRIONARIO DEL TRANSPORTE OVIDUCTAL EN HAMSTER

Review (2)

Consequences of nongenomic actions of estradiol on pathogenic genital tract response
Therapeutic Strategies Based on Polymeric Microparticles
72
Luis Velasquez

Director and Full Professor

Medicine

Universidad SEK

Santiago, Chile

10
Cristian Vilos

Profesor Jornada Completa

Medicina

Universidad de Talca

Talca, Chile

9
Paula Solar

Académico Investigador

Universidad SEK

Santiago, Chile

8
Alejandro Tapia

Profesor Asistente

Facultad de Medicina

Universidad de Chile

Santiago, Chile

6
Pedro Orihuela

Profesor Asociado

Biología

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

6
Kevin Maisey

Profesor Asistente

Centro de Biotecnología Acuícola

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

6
Carmen Imarai

Profesor Titular

Biología

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

6
Mariana Rios

Investigador

Facultad de Ciencias Biológicas

pontificia Universidad Católica de Chile

Santiago, Chile

6
Alexis Parada

PROFESOR ASISTENTE

REPRODUCCION

INSTITUTO DE INVESTIGACIONES MATERNO INFANTIL, FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

4
Ricardo Fernández

Associate Professor

Health

Universidad de Los Lagos

Osorno, Chile

4
Francisco Morales

Posdoctoral

Universidad de Chile. Centro FONDAP ACCDiS

Santiago, Chile

4
Fernando Gonzalez

Titular Professor

Facultad de Ciencias de la Vida

Universidad Andres Bello

Santiago, Chile

4
Felipe Simon

Profesor Titular

Department of Biological Sciences

UNIVERSIDAD ANDRES BELLO FAC DE CS BIOLOGICAS, DPTO DE CS BIOLOGICAS

Santiago, Chile

3
Mabel Moreno

Profesor

Universidad SEK

Santiago, Chile

3
Soledad Henriquez

Profesor Asistente

INSTITUTO DE INVESTIGACIONES MATERNO INFANTIL, FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

3
Ricardo Fernandez

Profesor Asociado A

Salud

Universidad de Los Lagos

Osorno, Chile

3
NATALIA JUICA

Bioquímico

Facultad de Ciencias de la Salud

Universidad SEK

Santiago, Chile

2
Luis Constandil

Profesor Titular

Biología

Universidad de Santiago de Chile

Santiago, Chile

2
Diego Varela

Profesor Asociado

Fisiología y Biofísica

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

2
Lorena Varela

Assistant Professor

Biological Sciences

Universidad Andres Bello

Santiago, Chile

2
Katherine Garcia

PROFESOR ASOCIADO

UNIVERSIDAD AUTONOMA DE CHILE

Santiago, Chile

2
Claudio Cabello

Full Professor

Ciencias Biologicas

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

2
Yolanda Vargas

Profesor Asociado

Producción Vegetal

UNIVERSIDAD DE CONCEPCIÓN

Chillán, Chile

2
Maria Otero

Profesor Asociado

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

2
Melissa Alegría

Académico Asociado

Facultad de Ingeniería y Negocios

Universidad de Las Américas

Santiago, Chile

2
Katherine Zepeda

alumno tesista

Quimica y Biologia

Universidad de Santiago de Chile

Santiago, Chile

1
Gareth Owen

Profesor Titular

Fisiologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Francisco Ceric

Jefe Laboratorio

Laboratorio de Neurociecia Afectiva

Facultad de Psicologia/Universidad del Desarrollo

Santiago, Chile

1
Guillermo González

FACULTAD DE CIENCIAS UIVERSIDAD DE CHILE

Santiago, Chile

1
Pablo Tapia

Jefe Técnico Unidad de Paciente Crítico (UPC)

Unidad Paciente Critico (UPC)

Hospital Clinico Metropolitano La Florida

Santiago, Chile

1
Claudia Riedel

Full Professor

Life Sciences

Universidad Andres Bello

Santiago, Chile

1
Alvaro Becerra

Coordinador Academico

Ciencias Químico y Biológicas

Universidad Bernardo O'Higgins

Santiago, Chile

1
Monica Caceres

Profesor asistente

Instituto de ciencias biomedicas

Universidad de Chile

Santiago, Chile

1
Oscar Cerda

Associate Professor

Molecular and Cellular Biology

Universidad de Chile

Santiago, Chile

1
Cesar Saldias

Profesor Asistente

de Química Física

Pontificia Universidad Catolica de Chile

Santiago, Chile

1
Ricardo Armisen

Associate Professor

Centro de Genética y Genómica

Universidad del Desarrollo

Santiago, Chile

1
César Echeverría

DIRECTOR DE INVESTIGACIÓN

Medicina

Universidad de Atacama

COPIAPO, Chile

1
VALERIA MARQUEZ

Profesor Asistente

Centro de Nanotecnologia Aplicada

Universidad Mayor de Chile

SANTIAGO, Chile

1
Juan Fuentes

Académico

Ciencias Biológicas

Universidad Andrés Bello

Santiago, Chile

1
Angel Leiva

Full Professor

Physical Chemistry

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
EVA BUSTAMANTE

JEFE DE COORDINACION CIENTIFICA

INVESTIGACION Y DOCENCIA

FUNDACION ARTURO LOPEZ PEREZ

Santiago, Chile

1
Claudio Figueroa

Profesor Asistente

Ciencias Biológicas y Quimicas

Universidad San Sebastian

Santiago, Chile

1
Daniel Aguayo

Assistant Professor

Molecular Biophysics & Bioinformatics Group

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

1
Ricardo Ramires

Assistant pofessor

Facultad de odontologia

Universidad de Chile

Santiago, Chile

1
Dora Altbir

Full Professor

Physic Department

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

1
Marlen Gutierrez

Investigador

Centro para el Desarrollo de la Nanociencia y Nanotecnologia

Universidad de Santiago de Chile

Santiago, Chile

1
Paula Rodas

Microbiology Consultant

Pan American Health Organization (PAHO - OPS/OMS Chile)

Vitacura, Chile

1
Alejandro Madrid

Academico Asociado

Química

Universidad de Playa ancha

Valparaíso, Chile

1
Juliano Casagrande

Profesor Titular

Fisica

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

1
Daniella Utz

Postdoctorado

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Pablo Nelson

Coordinador Área Bioquímica

Ciencias Básicas

Universidad Santo Tomás

Santiago, Chile

1
Gino Nardocci

Investigador

Universidad de Los Andes

Santiago, Chile

1
Patricia Arenas

Ingeniero de Proyectos

Patricia Arenas Riesco

Santiago, Chile

1
Alvaro Elorza

ASSOCIATE PROFESSOR

INSTITUTE OF BIOMEDICAL SCIENCES

UNIVERSIDAD ANDRES BELLO

Santiago, Chile