Man

Claudia Andrea Riedel Soria

Full Professor

Universidad Andres Bello

Santiago, Chile

Líneas de Investigación


The main research lines of our team are the celular, and molecular effects of hypothyroidism and hypothyroxinemia over the central nervous system, inflammatory diseases and immune system both the offspring as the adult.

Educación

  •  Biochemical, Pontificia Universidad Católica de Chile. Chile, 1995
  •  Master in Bioquimica, Pontificia Universidad Catolica de Chile. Chile, 1995
  •  Master in Science, Albert Einstein College of Medicine. Chile, 1998
  •  Pharmacology, Albert Einstein College of Medicine New York. Estados Unidos, 2002

Experiencia Académica

  •   Assistant Professor Part Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Biological Sciences

    Santiago, Chile

    1993 - 1993

  •   Assistan Professor Part Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Biological Sciences

    Santiago, Chile

    1994 - 1994

  •   Associate Professor Full Time

    UNIVERSIDAD DE LOS ANDES

    Biological Sciences

    Santiago, Chile

    2003 - 2004

  •   Full Professor Full Time

    UNIVERSIDAD ANDRES BELLO

    Life sciences

    Santiago, Chile

    2005 - A la fecha

Experiencia Profesional

  •   Research Associate Full Time

    Millennium Institute

    Santiago, Chile

    2005 - A la fecha

  •   Director del programa de bachillerato en ciencias Full Time

    Universidad Andres Bello

    Santiago, Chile

    2005 - 2009

Formación de Capital Humano


Enrique González, PhD candidate, Doctorate in Molecular Sciences, Universidad Andres Bello (2020)
Rosario Hernández, PhD candidate, Doctorate in Molecular Sciences, Universidad Andres Bello (2019)
Esteban Caamaño, PhD candidate, Doctorate in Molecular Sciences, Universidad Andres Bello (2019)
Linda Chamarro, research unit, regular course of the Master in engineer in biotechnology Universidad Andres Bello (2019).
Matías Estrella, research unit, regular course of engineer in biotechnology Universidad Andres Bello (2019).
Máximo Díaz, research unit, Master in biochemestry Universidad Andres Bello (2019).
Enrique González, research unit, Master in biochemestry Universidad Andres Bello (2019).
Tamara Escobedo, Master, Master in biochemestry Universidad Andres Bello (2018).
Bárbara Gutiérrez, Master, Master in biochemestry Universidad Andres Bello (2018).
Noelia Blanco, Master, Master in biochemestry Universidad Andres Bello (2017).
Yamil Marambio, Master, Master in biochemestry Universidad Andres Bello (2017).
Felipe Gomez, Master, Master in biochemestry Universidad Andres Bello (2017).
Gonzalo Vidal, Master, Master in engineer in biotechnology, Universidad Andres Bello (2015).
Maximiliano Michell, biochemestry, Universidad Catolica de Valparaiso (2014).
Katherine Acevedo, biochemestry, Universidad Catolica de Valparaiso (2014).
Beatriz Alvarez, Master, Master in engineer in biotechnology Universidad Andres Bello (2012-2014).
Gabriela Zuñiga, Master, Master in biochemestry Universidad Andres Bello (2012-2013).
Eduardo Albornoz, Master, Master in biochemestry Universidad Andres Bello (2011-2012).
Luis Venegas, PhD candidate, Doctorate in Molecular Biosciences, Universidad Andres Bello (2011-2017).
Pablo Cisternas, PhD candidate, Doctorate in Molecular Biosciences, Universidad Andres Bello (2010-2015).
Alejandro Arrriagada, PhD in Molecular Biosciences, Universidad Andres Bello (2007-2013).



 

Article (94)

Asymptomatic Herpes Simplex Virus Type 1 Infection Causes an Earlier Onset and More Severe Experimental Autoimmune Encephalomyelitis
Characterization of the Anti-Inflammatory Capacity of IL-10-Producing Neutrophils in Response to Streptococcus pneumoniae Infection
Crosstalk Between Epithelial Cells, Neurons and Immune Mediators in HSV-1 Skin Infection
Lung pathology due to hRSV infection impairs blood-brain barrier permeability enabling astrocyte infection and a long-lasting inflammation in the CNS
Eplerenone Implantation Improved Adipose Dysfunction Averting RAAS Activation and Cell Division
Naturally Derived Heme-Oxygenase 1 Inducers and Their Therapeutic Application to Immune-Mediated Diseases
SARS-CoV-2: Immune Response Elicited by Infection and Development of Vaccines and Treatments
The impact of the micronutrient iodine in health and diseases
Circulating Endothelial Cells From Septic Shock Patients Convert to Fibroblasts Are Associated With the Resuscitation Fluid Dose and Are Biomarkers for Survival Prediction
Copper deficiency- induced anemia is caused by a mitochondrial metabolic reprograming in erythropoietic cells
Cytokines in the Respiratory Airway as Biomarkers of Severity and Prognosis for Respiratory Syncytial Virus Infection: An Update
The absence of interleukin 10 affects the morphology, differentiation, granule content and the production of cryptidin-4 in Paneth cells in mice
Differential expression profile of CXCR3 splicing variants is associated with thyroid neoplasia. Potential role in papillary thyroid carcinoma oncogenesis?
Evaluation of monoclonal antibodies that detect conserved proteins from Respiratory Syncytial Virus, Metapneumovirus and Adenovirus in human samples
Gestational Hypothyroxinemia Affects Its Offspring With a Reduced Suppressive Capacity Impairing the Outcome of the Experimental Autoimmune Encephalomyelitis
Gestational Hypothyroxinemia Imprints a Switch in the Capacity of Astrocytes and Microglial Cells of the Offspring to React in Inflammation.
Persistent Salmonella enterica serovar Typhimurium infection increases the susceptibility of Mice to Develop intestinal inflammation
Role of Oxidative Stress as Key Regulator of Muscle Wasting during Cachexia
TGF-beta requires the activation of canonical and non-canonical signalling pathways to induce skeletal muscle atrophy
A Potential Role of Salmonella Infection in the Onset of Inflammatory Bowel Diseases
Aberrant T cell immunity triggered by human Respiratory Syncytial Virus and human Metapneumovirus infection
Endothelial-to-mesenchymal transition: Cytokine-mediated pathways that determine endothelial fibrosis under inflammatory conditions
Heme Oxygenase-1 Modulates Human Respiratory Syncytial Virus Replication and Lung Pathogenesis during Infection
Hormonal Modulation of Dendritic Cells Differentiation, Maturation and Function: Implications for the Initiation and Progress of Systemic Autoimmunity
Imprinting of maternal thyroid hormones in the offspring
Interleukin-10 Production by T and B Cells Is a Key Factor to Promote Systemic Salmomnella enterica Serovar Typhimurium Infection in Mice
Modulating the function of the immune system by thyroid hormones and thyrotropin
Modulation of Host Immunity by Human Respiratory Syncytial Virus Virulence Factors: A Synergic Inhibition of Both Innate and Adaptive Immunity
Gestational Hypothyroidism Improves the Ability of the Female Offspring to Clear Streptococcus pneumoniae Infection and to Recover From Pneumococcal Pneumonia.
Gestational Hypothyroxinemia Affects Glutamatergic Synaptic Protein Distribution and Neuronal Plasticity Through Neuron-Astrocyte Interplay.
Human Respiratory Syncytial Virus: Infection and Pathology.
Modulation of antigen processing by haem-oxygenase 1. Implications on inflammation and tolerance.
New insights about excisable pathogenicity islands in Salmonella and their contribution to virulence.
New insights on the viral and host factors contributing to the airway pathogenesis caused by the respiratory syncytial virus.
Opposing roles of IL-10 in acute bacterial infection.
Contribution of Dendritic cells to the autoimmune pathology of Systemic Lupus Erythematosus.
Excess iodide induces an acute inhibition of the sodium/iodide symporter in thyroid male rat cells by increasing reactive oxygen species.
Increases in reactive oxygen species enhance vascular endothelial cell migration through a mechanism dependent on the transient receptor potential melastatin 4 ion channel
Inflammatory damage on respiratory and nervous systems due to hRSV infection.
Interleukin-10 plays a key role in the modulation of neutrophils recruitment and lung inflammation during infection by Streptococcus pneumoniae.
Intravenous administration of bone marrow-derived mesenchymal stem cells induces a switch from classical to atypical symptoms in experimental autoimmune encephalomyelitis.
Modulation of Immunity and Inflammation by the Mineralocorticoid Receptor and Aldosterone.
Novel therapies and vaccines against the human respiratory syncytial virus.
Role of dendritic cells in the initiation, progress and modulation of systemic autoimmune diseases
The Expression of RAC1 and Mineralocorticoid Pathway-Dependent Genes are Associated With Different Responses to Salt Intake
Understanding Lung Immunopathology Caused by the Human Metapneumovirus: Implications for Rational Vaccine Design
Adaptive responses of mitochondria to mild copper deprivation involve changes in morphology, OXPHOS remodeling and bioenergetics
Central nervous system alterations caused by infection with the human respiratory syncytial virus
Conjugal transfer of the pathogenicity island ROD21 in Salmonella enterica serovar Enteritidis depends on environmental conditions
Induction of protective effector immunity to prevent pathogenesis caused by the respiratory syncytial virus. Implications on therapy and vaccine design
Modulation of host adaptive immunity by hRSV proteins
Respiratory syncytial virus detection in cells and clinical samples by using three new monoclonal antibodies
Surface expression of the hRSV nucleoprotein impairs immunological synapse formation with T cells.
Advances in understanding respiratory syncytial virus infection in airway epithelial cells and consequential effects on the immune response
Carbon monoxide decreases endosome-lysosome fusion and inhibits soluble antigen presentation by dendritic cells to T cells
Chromosomal excision of a new pathogenicity island modulates salmonella virulence in vivo
Copper deficiency alters cell bioenergetics and induces mitochondrial fusion through up-regulation of MFN2 and OPA1 in erythropoietic cells
Gene Elements that regulate Streptococcus pneumonia virulence and immunity evasion
Gestational hypothyroidism increases the severity of experimental autoimmune encephalomyelitis in adult offspring.
Impaired learning resulting from respiratory syncytial virus infection.
Impaired Spatial Memory in Mice Lacking CD3 zeta Is Associated with Altered NMDA and AMPA Receptors Signaling Independent of T-Cell Deficiency
Lipopolysaccharide induces a fibrotic-like phenotype in endothelial cells
Modulation of tumor immunity by soluble and membrane-bound molecules at the immunological synapse
A novel form of T cell antagonism by trapping of immunological synapse
Hypothyroidism in the adult rat causes incremental changes in brain-derived neurotrophic factor, neuronal and astrocyte apoptosis, gliosis, and deterioration of postsynaptic density
Mechanisms used by virulent Salmonella to impair dendritic cell function and evade adaptive immunity
Respiratory syncytial virus infection and immunity
Respiratory Syncytial Virus infection in mice reduces spatial learning capacity and long term potentiation.
Excision of an unstable pathogenicity island in Salmonella enterica serovar Enteritidis is induced during infection of phagocytic cells
Induction of Tolerogenic Dendritic Cells by NF-kappa B Blockade and Fc gamma Receptor Modulation
Local cytokine response upon respiratory syncytial virus infection
Modulation of the dendritic cell-T-cell synapse to promote pathogen immunity and prevent autoimmunity
Aldosterone Promotes Autoimmune Damage by Enhancing Th17-Mediated Immunity
Deletion of a prophage-like element causes attenuation of Salmonella enterica serovar Enteritidis and promotes protective immunity
Efficient lung recruitment of respiratory syncytial virus-specific Th1 cells induced by recombinant bacillus Calmette-Guérin promotes virus clearance and protects from infection
Excision of an unstable pathogenicity island in Salmonella enterica serovar Enteritidis is induced during infection of phagocytic cells
Salmonella pathogenicity island 1 differentially modulates bacterial entry to dendritic and non-phagocytic cells
T-cell antagonism by short half-life pMHC ligands can be mediated by an efficient trapping of T-cell polarization toward the APC
Altered chemokine receptor expression in papillary thyroid cancer
Impairment of T Cell Immunity by the Respiratory Syncytial Virus: Targeting Virulence Mechanisms for Therapy and Prophylaxis
Modulation of nuclear factor-kappaB activity can influence the susceptibility to systemic lupus erythematosus
Activating and inhibitory Fc gamma receptors can differentially modulate T cell-mediated autoimmunity
Host immunity during RSV pathogenesis
Maternal hypothyroxinemia impairs spatial learning and synaptic nature and function in the offspring
Protective T cell immunity against respiratory syncytial virus is efficiently induced by recombinant BCG
Respiratory syncytial virus impairs T cell activation by preventing synapse assembly with dendritic cells
Host immunity during RSV pathogenesis
The sodium/iodide symporter (NIS): Characterization, regulation, and medical significance
Polarized trafficking of thyrocyte proteins in MDCK cells
Journey of the iodide transporter NIS: from its molecular identification to its clinical role in cancer
Post-transcriptional regulation of the sodium/iodide symporter by thyrotropin
Prolactin negatively regulates caveolin-1 gene expression in the mammary gland during lactation, via a Ras-dependent mechanism
N-linked glycosylation of the thyroid Na+/I- symporter (NIS) - Implications for its secondary structure model
Characterization of the thyroid Na+/I- symporter with an anti-COOH terminus antibody

Abstract (1)

Molecular Mechanism Associated to the Offspring's Cognitive Impairment due to Maternal Thyroid Hormones Deficiency during Gestation

Errata (1)

The ArcAB two-component regulatory system promotes resistance to reactive oxygen species and systemic infection by Salmonella Typhimurium (vol 13, e0203497, 2018)

Review (13)

BCG-Induced Cross-Protection and Development of Trained Immunity: Implication for Vaccine Design
Herpes Simplex Virus Type 1 Infection of the Central Nervous System: Insights Into Proposed Interrelationships With Neurodegenerative Disorders
Assessing the Importance of Domestic Vaccine Manufacturing Centers: An Overview of Immunization Programs, Vaccine Manufacture, and Distribution
Expanding the Current Knowledge About the Role of Interleukin-10 to Major Concerning Bacteria
Heme Oxygenase-1 as a Modulator of Intestinal Inflammation Development and Progression
Human metapneumovirus: Mechanisms and molecular targets used by the virus to avoid the immune system
Intestinal Microbiota Influences Non-intestinal Related Autoimmune Diseases
Role of regulatory t cells in infection and vaccination during early infancy
Innate immune cells for immunotherapy of autoimmune and cancer disorders
Contribution of autophagy to antiviral immunity
Contribution of dendritic cells to the autoimmune pathology of systemic lupus erythematosus
Genetic and Pharmacological Modulation of Dendritic Cell-T Cell Interactions as a Therapeutic Strategy for Systemic Lupus Erythematosus
Virulence Mechanisms Displayed by Salmonella to Impair Dendritic Cell Function
80
Claudia Riedel

Full Professor

Life Sciences

Universidad Andres Bello

Santiago, Chile

27
Susan Bueno

Profesor Asociado

Genética Molecular y Microbiología

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

10
Maria Opazo

Profesor honorarios

Ciencias Biologicas

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

9
Alexis Kalergis

Full Professor

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE. FACULTAD DE CIENCIAS BIOLÓGICAS

Santiago, Chile

8
Pablo González

Associate Professor

Molecular Genetics and MIcrobiology

Pontificia Universidad Católica de Chile

Santiago, Chile

5
Leandro Carreño

Profesor Asistente

Instituto de Ciencias Biomédicas

Universidad de Chile

Santiago, Chile

5
Felipe Simon

Profesor Titular

Department of Biological Sciences

UNIVERSIDAD ANDRES BELLO FAC DE CS BIOLOGICAS, DPTO DE CS BIOLOGICAS

Santiago, Chile

5
Alvaro Elorza

FULL PROFESSOR

INSTITUTE OF BIOMEDICAL SCIENCES

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

4
Carolina Llanos

Associate Professor

Pontificia Universidad Católica de Chile

Santiago, Chile

4
Yaneisi Vazquez

Directora técnica de proyectos

Genética Molecular

Pontificia Universidad Católica de Chile

Santiago, Chile

4
Gisela Canedo

Investigadora y Profesora

Facultad de Odontología

Universidad de Los Andes

Santiago, Chile

3
Hernán Peñaloza

Postdoctoral associate

Department of Medicine

University of Pittsburgh

Pittsburgh, Estados Unidos

3
Catalina Pardo

Investigador Postdoctoral

Genética Molecular y Microbiología

Pontificia Universidad Católica de Chile

Region Metropolitana, Chile

3
Eduardo Leiva

Profesor Asistente

Departamento de Ingeniería Hidráulica y Ambiental/ Departamento de Química Inorgánica

Pontificia Universidad Católica de Chile, Facultad de Química, Escuela de Ingeniería

Santiago, Chile

3
Claudio Cabello

Full Professor

Ciencias Biologicas

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

3
Karen Bohmwald

Investigador Postdoctoral

Pontificia Universidad Católica de Chile

Santiago, Chile

3
Natalia Muñoz

Estudiante de Doctorado y Jefe Alterno_Proyecto COPEC-UC R772

Genética Molecular y Microbiología

Pontificia Universidad Católica de Chile

Santiago, Chile

3
Jorge Soto

Asistente de Investigacion

Pontificia Universidad Católica de Chile

Santiago, Chile

3
Carolina Llanos

Profesor Asociado

Inmunología Clínica y Reumatología

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

3
Carlos Fardella

Profesor Titular

Endocrinología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

2
Carlos Lagos

Profesor Asociado

FACULTAD DE MEDICINA Y CIENCIA

UNIVERSIDAD SAN SEBASTIÁN

SANTIAGO, Chile

2
Manuel Alvarez

Gastroenterologist and Chief of Institute of Medicine

Gastroenterology

Pontificia Universidad Católica de Chile

Santiago, Chile

2
Andrea Vecchiola

Profesor Asistente

Endocrinologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

2
LILIANA GONZÁLEZ

Investigador

Departamento de Laboratorios Clínicos

Pontificia Universidad Católica de Chile

Santiago, Chile

2
Cristian Carvajal

Associate Professor

Endocrinologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

2
Luis Venegas

Bioquímico/investigador

Anatomía Patológica

Clínica Alemana de Santiago

Santiago, Chile

2
Loni Berkowitz

Investigador postdoctoral

Nutrición, diabetes y metabolismo

Pontificia Universidad Católica de Chile

SANTIAGO, Chile

2
Pablo Tapia

Jefe Técnico Unidad de Paciente Crítico (UPC)

Unidad Paciente Critico (UPC)

Hospital Clinico Metropolitano La Florida

Santiago, Chile

2
Omar Vallejos

Asistente de Investigación

Genética Molecular y Microbiología

Pontificia Universidad Católica de Chile

Santiago, Chile

2
Alvaro Becerra

Profesor Asociado

Ciencias Químico y Biológicas

Universidad Bernardo O'Higgins

Santiago, Chile

2
Hugo Tobar

Associate Reserch

Department of Gastroenterology

Pontificia Universidad Católica de Chile

Santiago, Chile

2
Margarita Lay

PROFESOR ASISTENTE

BIOTECNOLOGÍA

UNIVERSIDAD DE ANTOFAGASTA

ANTOFAGASTA, Chile

2
Luis Michea

PROFESOR ASOCIADO

PROGRAMA FISIOLOGIA Y BIOFISICA

UNIVERSIDAD DE CHILE

Santiago, Chile

2
Cristian Vilos

Profesor Jornada Completa

Medicina

Universidad de Talca

Talca, Chile

1
FELIPE MELO

Investigador postdoctoral

Genetica Molecular y Microbiología

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Christian Palavecino

Profesor asistente

Universidad Central de Chile

Santiago, Chile

1
Juan Roa

Chair

Pathology

Pontificia Universidad Catolica de Chile

santiago, Chile

1
Rodrigo Fuentealba

Postdoctoral Research Associate

Departamento de Inmunología Clínica y Reumatología / Facultad de Medicina

Pontificia Universidad Católica

Santiago, Chile

1
Marcelo Lopez

Profesor Titular

Infectologia e Inmunologia Pediatrica

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

1
Fidel Allende

Quimico

Laboratorios Clinicos

Pontificia Universidad Católica de Chile

Santiago, Chile

1
KATIA ABARCA

Profesor Titular

Pediatría

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

1
Cristián Amador

Profesor Asistente

Universidad San Sebastián

Santiago, Chile

1
Maria Otero

Profesor Asociado

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

1
Francisco Salazar

Profesional Asistente

Genética Molecular y Microbiología

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Marcela Ferres

Head of Department

Pediatric Infectious Diseases and Immunology

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Nicolás Gálvez

Asistente de Investigación

Genética Molecular y Microbiología

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Paulina Orellana

Coordinadora traslacional

Universidad de Chile

Santiago, Chile

1
Diego Varela

Profesor Asociado

Fisiología y Biofísica

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

1
Alejandro Martinez

Profesor Asociado

Pediatría

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago de Chile, Chile

1
Luis Velasquez

Director and Full Professor

Medicine

Universidad SEK

Santiago, Chile

1
Camila Covián

Investigador

Genética molecular y microbiología

Pontificia Universidad Católica

Santiago, Chile

1
Monica Caceres

Profesor asociado

Instituto de ciencias biomedicas

Universidad de Chile

Santiago, Chile

1
Oscar Cerda

Associate Professor

Molecular and Cellular Biology

Universidad de Chile

Santiago, Chile

1
Orlando Acevedo

Tesista de Doctorado

Genetica Molecular y Microbiología

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Carolina Prado

Investigador Joven

Fundacion Ciencia y Vida

Santiago, Chile

1
Emma Rey

Professor/Researcher

Instituto de Ciencias e Innovación en Medicina (ICIM)

Universidad del Desarrollo

Santiago, Chile

1
Gareth Owen

Profesor Titular

Fisiologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Johanna Ábrigo

Bioquímico

Centro de Bioinformática y Biología Integrativa

Santiago, Chile

1
César Echeverría

DIRECTOR DE INVESTIGACIÓN

Medicina

Universidad de Atacama

COPIAPO, Chile

1
ALEJANDRA TAPIA

Investigador

Endocrinología

Pontificia Universidad Católica de Chile

Santiago, Chile

1
ANGELLO RETAMAL

Profesor Asistente

Biotecnología

Universidad de Antofagasta

Antofagasta, Chile

1
DIANA ALVAREZ

Egresado Doctorado Ciencias Biológicas

Pontificia Universidad Católica de Chile

Santiago de Chile, Chile

1
Felipe Tapia

Líder de grupo

Bioprocess Engineering

Max Planck Institute for Dynamics of Complex Technical Systems

Magdeburg, Alemania

1
Farides Saavedra

Investigadora

Fundación Ciencia y Vida

Ñuñoa, Chile

1
Fernando Figueroa

Director

Medicina

UNIVERSIDAD DE LOS ANDES

Santiago de Chile, Chile