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ALEJANDRA TAPIA CASTILLO

Investigador

Pontificia Universidad Católica de Chile

Santiago, Chile

Líneas de Investigación


Hipertensión arterial endocrina Epigenética exosomas

Educación

  •  Doctor en ciencias e innovación en medicina, UNIVERSIDAD DEL DESARROLLO. Chile, 2019

Experiencia Académica

  •   Investigador Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Medicina

    Santiago, Chile

    2018 - 2020

  •   Investigador Part Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Medicina

    Santiago, Chile

    2020 - A la fecha

Experiencia Profesional

  •   Investigador asistente Full Time

    Pontificina Universidad Católica de Chile

    Santiago, Chile

    2013 - 2014

  •   Investigador asistente Part Time

    Millenium Institute of Immunology and Immunoterapy

    Santiago, Chile

    2018 - A la fecha

  •   Visiting Scientist Full Time

    University of Queensland

    Santiago, Chile

    2017 - Sin Información

Premios y Distinciones

  •   ISE travel grant

    International Society of Endocrinology

    Estados Unidos, 2014

    Recognition of their effectiveness in endocrine research by International Society of Endocrinology at 2014

  •   Best Translational Study awarded

    SOCHED

    Chile, 2016

    Best Translational Study awarded by the Chilean Society of Endocrinology and Diabetes 2016

  •   Presidential Abstract

    ENDO Society

    Estados Unidos, 2016

    The Presidential Poster Competition is an event where high-scoring trainees who are presenting-authors of a poster presentation compete amongst their peers.

  •   Best published international article

    SOCHED

    Chile, 2016

    the Best published international article granted by SOCHED at 2016.


 

Article (15)

Proteomic Profile of Urinary Extracellular Vesicles Identifies AGP1 as a Potential Biomarker of Primary Aldosteronism
Classic and Nonclassic Apparent Mineralocorticoid Excess Syndrome
Downregulation of exosomal miR-192-5p and miR-204-5p in subjects with nonclassic apparent mineralocorticoid excess
The Aldosterone/Renin Ratio Predicts Cardiometabolic Disorders in Subjects Without Classic Primary Aldosteronism
Clinical, Biochemical, and Genetic Characteristics of "Nonclassic" Apparent Mineralocorticoid Excess Syndrome
Serum Cortisol and Cortisone as Potential Biomarkers of Partial 11 beta-Hydroxysteroid Dehydrogenase Type 2 Deficiency
Sodium Intake Is associated With Endothelial Damage Biomarkers and Metabolic Dysregulation
Hypertensive Patients That Respond to Aldosterone Antagonists May Have a Nonclassical 11 beta-HSD2 Deficiency
Citosine-Adenine-Repeat Microsatellite of 11 beta-hydroxysteroid dehydrogenase 2 Gene in Hypertensive Children
Cortisol/cortisone ratio and matrix metalloproteinase-9 activity are associated with pediatric primary hypertension
Usefulness and Pitfalls in Sodium Intake Estimation: Comparison of Dietary Assessment and Urinary Excretion in Chilean Children and Adults
The Expression of RAC1 and Mineralocorticoid Pathway-Dependent Genes are Associated With Different Responses to Salt Intake
Identification of novel 11 beta-HSD1 inhibitors by combined ligand- and structure-based virtual screening
Polymorphisms in the RAC1 Gene Are Associated With Hypertension Risk Factors in a Chilean Pediatric Population
Different effects of progesterone and estradiol on chimeric and wild type aldosterone synthase in vitro

Proyecto (6)

Perfil de expresión de miRNA en exosomas urinarios en sujetos pediátricos con déficit parcial de la enzima 11βHSD2
Millenium institute of Immunology and immunoteraphy
NOVEL BIOCHEMICAL AND EPIGENETIC STUDIES IN 11BETA-HYDROXYSTEROID DEHYDROGENASE 2 GENE AS A TARGET FOR ENDOCRINE HYPERTENSION.
REGULACIÓN DE LA ENZIMA 11Β-HIDROXIESTEROIDE DESHIDROGENASA TIPO 2 (11ΒHSD2) POR MIRNA Y SU ASOCIACIÓN CON HIPERTENSIÓN ARTERIAL
SALT INTAKE IN ESSENTIAL HYPERTENSION=> STUDIES OF NEW BIOCHEMICAL AND GENETIC MECHANISMS TO IDENTIFY ITS ETIOLOGY
PRIMARY ALDOSTERONISM AND HSD11B2 ENZYME ACTIVITY DEFECTS IN PEDIATRIC POPULATION AND ITS IMPACT ON THE GENERATION OF ENDOTHELIAL INJURY, OXIDATIVE STRESS AND ARTERIAL HYPERTENSION
15
Cristian Carvajal

Associate Professor

Endocrinologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

15
ALEJANDRA TAPIA

Investigador

Endocrinología

Pontificia Universidad Católica de Chile

Santiago, Chile

9
Carlos Fardella

Profesor Titular

Endocrinología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

8
Andrea Vecchiola

Profesor Asistente

Endocrinologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

7
Alejandro Martinez

Profesor Asociado

Pediatría

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago de Chile, Chile

7
Rene Baudrand

Profesor Asociado

Endocrinología

Pontificia Universidad Católica de Chile

Santiago, Chile

7
Fidel Allende

Quimico

Laboratorios Clinicos

Pontificia Universidad Católica de Chile

Santiago, Chile

6
Carlos Lagos

Profesor Asociado

FACULTAD DE MEDICINA Y CIENCIA

UNIVERSIDAD SAN SEBASTIÁN

SANTIAGO, Chile

6
Sandra Solari

Profesor Asociado

Departamento Laboratorios Clinicos - Facultad de Medicina - PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

3
Gareth Owen

Profesor Titular

Fisiologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

2
Carolina Loureiro

Instructor Adjunto

Pediatria

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Luis Michea

PROFESOR ASOCIADO

PROGRAMA FISIOLOGIA Y BIOFISICA

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Mariana Cifuentes

Professor

Instituto de Nutricion y Tecnologia de los Alimentos

INTA UNIVERSIDAD DE CHILE

Santiago, Chile

1
Lorena Garcia

Assistant Professor

Bioquimica y Biologia Molecular

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Claudia Riedel

Full Professor

Life Sciences

Universidad Andres Bello

Santiago, Chile

1
María Rojas

Jefa de Departamento

Medicina Familiar

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Pia Villarroel

Docente investigador

UNIVERSIDAD MAYOR

Santiago, Chile