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Gareth Ivor Owen Jardine

Profesor Titular

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Oncologia; Biologia Molecular; Cancer; Canceres Ginecologicos; Biologia del cancer; Terapias Biologicas del cancer; angiogenesis; vascularogenic mimicry; Immunoterapia en cancer

Biotecnologia, KINGS COLLEGE LONDON. Reino Unido, 1992
Bioquimica, UNIVERSITY OF LONDON. Chile, 1996

Profesor Asistente / Asociado Full Time

Pontificia Universidad Católica de Chile

Ciencias Biológicas

Santiago, Chile

2000 - 2018
Profesor Titular Full Time

Pontificia Universidad Católica de Chile

Ciencias Biológicas

Santiago, Chile

2018 - A la fecha
Profesor Titular Full Time

Pontificia Universidad Católica de Chile

Medicina

Santiago, Chile

2018 - A la fecha

Post doctorado Full Time

University of Colorado Health Science Center

Denver, Estados Unidos

1996 - 1998
Postdoctorado Full Time

Institute of Cancer Reseach

Londres, Reino Unido

1998 - 2000
Medical Directior Part Time

Mygoldex Chile (Biotech cGMP Company)

Santiago, Chile

2004 - 2007
Board Member Part Time

Fundación Foro Nacional de Cancer

Santiago, Chile

2012 - A la fecha
Board Member Part Time

Grupo Oncológico Cooperativo Chileno de Investigación

Santiago, Chile

2016 - A la fecha

Tutored Students: Post-graduate level (MSc & PhD)

Doctoral Student Program University Stage Participation

José Manuel Araya Chemistry PUC First year co-tutor
Mairelyz Garcia Chemistry PUC Second year co-tutor
Nicole Babbitt Physiology PUC Second year Tutor
Nicolle Santander Physiology PUC Third year Tutor
Cristian Espinoza Physiology PUC Final rear Tutor

24. Catalina Asencio Physiology PUC Graduated 2024 Tutor
23. Cristian Reyes Physiology PUC Graduated 2024 Tutor
22.Gabriel Mingo Physiology PUC Graduated 2023 Tutor
21. Charlotte Hill Physiology PUC Graduated 2021 Tutor
20. Miguel Córdova Q&F, U. Chile Graduated 2020 Tutor
19. Cristobal Fuentes Physiology PUC Graduated 2020 co-tutor
18. Monica Marquez Physiology PUC Graduated 2019 Tutor
17. Andres Valdivia Physiology PUC Graduated 2019 Tutor
16. Maximiliano Arce Physiology PUC Graduated 2019 Tutor
15.Dusan Racordon Physiology PUC Graduated 2018 Tutor
14. Renan Orellana Physiology PUC Graduated 2014 Tutor
13. Rafaela Erices Biomedicine U.Andrés Bello Graduated 2013 Tutor
12. Cristian Carvajal Medicine PUC Graduated 2013 co-tutor
11. Soledad Lange Physiology PUC Graduated 2012 Tutor
10. Macarena Vargas Physiology PUC Graduated 2011 Tutor
9. Ma. Loreto Bravo Physiology PUC Graduated 2010 Tutor
8. Marisol Quezada Physiology PUC Graduated 2009 Tutor
7. Soledad Henríquez Physiology PUC Graduated 2019 Tutor
6. Evelyn Aranda Physiology PUC Graduated 2008 Tutor
5. Ethel Velasquez Physiology PUC Graduated 2008 Tutor
4. Anil Sadarangani Physiology PUC Graduated 2008 Tutor
3. Ana Maria Meneses Biomedicine U.Andres Bello Graduated 2006 Tutor
2. Mauricio Pinto Physiology PUC Graduated 2005 Tutor
1. Andrés Carvajal Physiology PUC Graduated 2004 Tutor

Masters Student Program University Stage Participation

3. Jose Vasquez Reyes Med. Sciences U Chile Second year Tutor
2. Antonella Rosati Cell Biology. PUC Graduated 2017 co-tutor
1. Sumie Kato Physiology PUC Graduated 2004 Tutor

Tutoring of undergraduates

27. Javiera Veas (2024)
26. Josefa Fuenzalida (2024)
25. Sofia Salas (2024)
24. Nicolas Gallardo (2024)
23. Cristobal Canales (2024)
22. Daniela Tapia (2024)
21. German Cabrera (2023)
20. Anais Muñoz (2023)
19. Isidora Vega (2023)
18. Nicole Babbitt (2023)
17. Nayareth Balladares (2022)
16.- Fernando Zapapa (2022)
15. Gabriela Maita (2021)
14. Javiera Pradena (2020)
13. Varina Aldana (2020)
12. Camille Cabrioler (2018)
11. Gabriel Mingo (2018)
10. Isidora Arriagada (2016)
9. Maximiliano Arce (2015)
8. Andres Valdivia (2014)
7. Sofia Cubillos (2014)
6. Carolina Ramirez (2013)
5. Dusan Racordon (2012)
4. Felipe Orge (2012)
3. Jorge Diaz (2008)
2. Maria Soledad Lange (2006)
1. Maria Loreto Bravo (2006)

Grants (selected)

Actual:
Instituto Milenio IMII P09/016-F 2016-2027 (PI), FONDECYT No.1220586, 2022-2026; FONDAP CECAN 2022-2027 (Associate-investigator), FONDECYT Dra Zacconi (co-inestigator)

Previous (selected):
FONDECYT No.2002-2026 (Como PI: No. 1020715, 2002-2006, No. 1060495, 2006-2010, No. 1100870 2010-2014, PI: No. 1140970, 2014-2018, No.1180173, 2018-2022 No.1180241, 2018-2022, No.1220586, 2022-2026), Horizon 2020 Legacy (co-investigator, 2018-2024), FONDAP CECAN 2022-2027 (Associate-investigator), FONDAP ACCDis 2014-2024 (associate investigator), Roche PanCancer (Co-PI) 2020-2021. Bristol Myers Squibb CA209-8F3 2017-2019 (co-PI), Vice-rectory PUC Interdisciplinary grant N° II15058 (co-PI) 2016-2018, Grants (selected)

Patent Applications

Andrea Vecchiola, Cristian Carvajal, María del Carmen Campino, Sandra Solari, Fidel Allende, Gareth Owen, Carlos Fardella.
Methods to identify inhibitors of 11?-HSD1. Application (DPI): 5237 20150115 P- 11BHSD1. Enero 2015

Owen, GI. Bravo, María Loreto, Kato Sumie, Cuello, Mauricio, Orellana, Renán, Gonzalez, Pamela.
Process for obtaining cell culture to perform personalized medicine. Application a (DPI): Pat 3449-2014 Dec 2014

Ma. Soledad Lange Smith, Evelyn Aranda Jaque y Gareth Owen.
Use of coagulation Factor X and Xa in the treatment of angiogenic disorders”. Application (DPI): Jan 2013, No. 300912

Owen GI., Sadarangani A., Velasquez E., Croxatto H:
Use of a FSH fraction in the control of cell proliferation.
Reception at Patent Office (DPI): 10/12/08 December 2008. No. 03692 PCT, Diciembre 11, 2009


Comprehensive histopathological analysis of gastric cancer in European and Latin America populations reveals differences in PDL1, HER2, p53 and MUC6 expression Martinez-Ciarpaglini, Carolina; Barros, Rita; Caballero, Carmelo; Boggino, Hugo; Alarcon-Molero, Lorena; Peleteiro, Barbara; Ruiz-Garcia, Erika; Fernandez-Figueroa, Edith; Herrera-Goepfert, Roberto; Diaz-Romero, Consuelo; et al. Article ISI GASTRIC CANCER (2025)
Immune profiling of gastric adenocarcinomas in EU and LATAM countries identifies global differences in immune subgroups and microbiome influence van Schooten, Tessa S.; Cabeza-Segura, Manuel; Ferreira, Rui M.; Martinez-Ciarpaglini, Carolina; Barros, Rita; Santos-Antunes, Joao; Costa, Andreia; Fernandez-Figueroa, Edith A.; Lino-Silva, Leonardo; Hernandez-Guerrero, Angelica Ixtaccihuatl; et al. Article ISI BRITISH JOURNAL OF CANCER (2025)
Integrated clinico-molecular analysis of gastric cancer in European and Latin American populations: LEGACY project Dienstmann, R.; Ruiz-Garcia, E; Alsina, M.; Ruiz-Pace, F.; Groen-van Schooten, T. S.; Martinez-Ciarpaglini, C.; Fernandez-Figueroa, E. A.; Herrera-Goepfert, R.; Diaz-Romero, C.; Lino-Silva, L.; et al. Article ISI ESMO OPEN (2025)
A snapshot of cancer in Chile II: an update on research, strategies and analytical frameworks for equity, innovation and national development Vacarezza, Cristobal; Periera, Ana; Ferreccio, Catterina; Goic, Carolina Article ISI BIOLOGICAL RESEARCH (2024)
Assessing the Occurrence and Influence of Cancer Chemotherapy-Related Pharmacogenetic Alleles in the Chilean Population Garrido, Marcelo; Miquel, Juan Francisco Article ISI PHARMACEUTICS (2024)
Beyond tobacco: genomic disparities in lung cancer between smokers and never-smokers Garrido, Javiera; Rivas, Solange; Assar, Rodrigo; Lizana, Rodrigo; Ramos, Liliana; Perez, Paola; Fernandez, Cristina; Aguila, Jacqueline Flores; Dossetto, Giuliano Bernal; Olea, Monica Ahumada; et al. Article ISI BMC CANCER (2024)
Gastric cancer hospital-based registry: real-world gastric cancer data from Latin America and Europe Freile, B.; van Schooten, T.S.; Derks, S.; Carneiro, F; Figueiredo, C.; Barros, R.; Gauna, C.; Pereira, R; Romero, M.; Riquelme, A.; et al. Article ESMO Gastrointestinal Oncology (2024)
Quadruple therapies show a higher eradication rate compared to standard triple therapy for Helicobacter pylori infection within the LEGACy consortium. A multicenter observational study in European and Latin American countries Medel-Jara, Patricio; Reyes Placencia, Diego; Anton, Rosario; Jimenez, Elena; Miralles-Marco, Ana; Caballero, Carmelo; Boggino, Hugo; Barros, Rita; Santos-Antunes, Joao; Diez, Marc; et al. Article ISI UNITED EUROPEAN GASTROENTEROLOGY JOURNAL (2024)
Cancer Stem Cell and Aggressiveness Traits Are Promoted by Stable Endothelin-Converting Enzyme-1c in Glioblastoma Cells Erices, Jose I.; Toro, Maria A.; Villalobos-Nova, Karla; Gaete-Ramirez, Belen; Owen, Gareth I. I.; Quezada-Monras, Claudia; Tapia, Julio C. C. Article ISI CELLS (2023)
Differentially Expressed Genes and Signaling Pathways Potentially Involved in Primary Resistance to Chemo-Immunotherapy in Advanced-Stage Gastric Cancer Patients Bravo, MariaLoreto; Fernandez, M. Fernanda; Garrido, Marcelo Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)
A case-control study of a combination of single nucleotide polymorphisms and clinical parameters to predict clinically relevant toxicity associated with fluoropyrimidine and platinum-based chemotherapy in gastric cancer Hill, Charlotte N.; Garrido, Marcelo Article ISI BMC CANCER (2021)
Cancer Research in Latin America, 2014-2019, and its Disease Burden Cazap, Eduardo; Unger Saldana, Karla; Dreyer, Marisa; Tsunoda, Audrey Article ISI JOURNAL OF SCIENTOMETRIC RESEARCH (2021)
Impact of the Potential Antitumor Agent 2-(4-Hydroxyphenyl) Amino-1,4-Naphthoquinone (Q7) on Vasomotion Is Mediated by the Vascular Endothelium, But Not Vascular Smooth Muscle Cell Metabolism Palacios, Javier; Chiong, Mario; Paredes, Adrian; Cifuentes, Fredi Article ISI JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2021)
Mechanobiology of Autophagy: The Unexplored Side of Cancer Criollo, Alfredo Article ISI FRONTIERS IN ONCOLOGY (2021)
A Molecular Stratification of Chilean Gastric Cancer Patients with Potential Clinical Applicability Acevedo, Francisco; Koch, Erica; Madrid, Jorge; Torres, Javiera; Garrido, Marcelo Article ISI CANCERS (2020)
Deciphering the Role of the Coagulation Cascade and Autophagy in Cancer-Related Thrombosis and Metastasis Hill, Charlotte Nicole; Torres, Begona; Solis, Benjamin Article ISI FRONTIERS IN ONCOLOGY (2020)
Eplerenone Implantation Improved Adipose Dysfunction Averting RAAS Activation and Cell Division Vecchiola, Andrea; Lagos, Carlos F.; Opazo, Maria Cecilia; Riedel, Claudia A. Article ISI FRONTIERS IN ENDOCRINOLOGY (2020)
Multi-Objective Optimization for Personalized Prediction of Venous Thromboembolism in Ovarian Cancer Patients Cuello, Mauricio Article ISI IEEE JOURNAL OF BIOMEDICAL AND HEALTH INFORMATICS (2020)
The Reprimo-Like Gene Is an Epigenetic-Mediated Tumor Suppressor and a Candidate Biomarker for the Non-Invasive Detection of Gastric Cancer Alejandra Alarcon, Maria; Amigo, Julio; Norero, Enrique; Garrido, Marcelo Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Chilean Registry for Neuroendocrine Tumors: A Latin American Perspective Pinto, MP; Medel, MM; Retamal, IN; Bravo, ML; Valenzuela, Y; Galindo, H; Pena J.; Madrid J.; Nilo, F.; Guarda, FJ; et al. Article ISI SCOPUS HORMONES & CANCER (2019)
Coagulation Factor Xa Promotes Solid Tumor Growth, Experimental Metastasis and Endothelial Cell Activation Lange, Soledad; Ramirez, Carolina; Cautivo, Kelly; Kalergis, Alexis M.; Lladser, Alvaro; Valenzuela, Guillermo; Saéz, Claudia; Godoy, Alejandro; Leyton, Lisette Article ISI SCOPUS CANCERS (2019)
Fact or Fiction, It Is Time for a Verdict on Vasculogenic Mimicry? Aldana V.; Pinto, M. P.; Owen, G. I. Article ISI SCOPUS FRONTIERS IN ONCOLOGY (2019)
High Proportion of Potential Candidates for Immunotherapy in a Chilean Cohort of Gastric Cancer Patients: Results of the FORCE1 Study Munoz-Medel, Matias; Fernandez, Maria F.; Acevedo, Francisco; Madrid, Jorge; Koch, Erica; Jose Maturana, Maria; Torres, Javiera; Caceres, Javier; Lizana, Rodrigo; Ramos, Liliana; et al. Article ISI SCOPUS CANCERS (2019)
Targeted deep sequencing from multiple sources demonstrates increased NOTCH1 alterations in lung cancer patient plasma AI-Dherasi A.; Zou K.; Sufiyan S.; Owen, G. I. Article ISI SCOPUS CANCER MEDICINE (2019)
The Reprimo gene family member, reprimo-like (rprml), is required for blood development in embryonic zebrafish Reig, German; Wichmann, Ignacio A.; Opazo, Juan C.; Owen, Gareth I.; Amigo, Julio D. Article ISI SCOPUS SCIENTIFIC REPORTS (2019)
Using plasma cell-free DNA to monitor the chemoradiotherapy course of cervical cancer Tian, Jichao; Geng, Yan; Lv, Dekang; Li, Peiying; Cordova, Miguel; Liao, Yuwei; Tian, Xiaoyuan; Zhang, Xiaolong; Zhang, Qingzheng; Zou, Kun; et al. Article ISI SCOPUS INTERNATIONAL JOURNAL OF CANCER (2019)
Chilean Gastric Cancer Task Force A study protocol to obtain a clinical and molecular classification of a cohort of gastric cancer patients Owen, Gareth I.; Retamal, Ignacio N.; Fernadez, Maria F.; Cisternas, Betzabe; Acevedo, Francisco; Madrid, Jorge; Pena, Jose; Maturana, Maria Jose; Cordova-Delgado, Miguel; Torres, Javiera; et al. Article ISI MEDICINE (2018)
Conflicts of CpG density and DNA methylation are proximally and distally involved in gene regulation in human and mouse tissues Chen, F; Deng, X; Lv D.; Li, P; Diao Y.; Owen, G. I. Article ISI SCOPUS Epigenetics (2018)
Expression of RPRM/rprm in the Olfactory System of Embryonic Zebrafish (Danio rerio) Stanic K.; Lemus, CG; Wichmann, IA; Corvalán, AH; Concha, ML; Amigo, JD Article ISI SCOPUS FRONTIERS IN NEUROANATOMY (2018)
Patient inflammatory status and CD4+/CD8+ intraepithelial tumor lymphocyte infiltration are predictors of outcomes in high-grade serous ovarian cancer Pinto, M. P.; Bravo, M. L.; Owen, G. I.; Roa, JC; Cuello, M. A. Article ISI SCOPUS Gynecologic Oncology (2018)
Simvastatin interferes with cancer stem-cell plasticity reducing metastasis in ovarian cancer Liberona, MF; Bravo, ML; Gejman, R; Montecinos, V. Article ISI SCOPUS ENDOCRINE-RELATED CANCER (2018)
Diabetic concentrations of metformin inhibit platelet-mediated ovarian cancer cell progression Santoro, Felice; Orellana, Renan; Fuenzalida, Patricia; Ibanez, Carolina; Bravo, Erasmo; Arab, Clemente; Bustos, Galdo; Cesar Cardenas, Julio Article ISI SCOPUS ONCOTARGET (2017)
Diabetic concentrations of metformin inhibit platelet-mediated ovarian cancer cell progression Erices, Rafaela; Cubillos, Sofía; Aravena, Raúl; Santoro, Felice; Marquez, Monica; Orellana, Renan; Ramírez, Carolina; González, Pamela; Fuenzalida, Patricia; Bravo, María Loreto; Oliva, Bárbara; Kato, Sumie; Ibañez,Carolina; Brañes, Jorge; Bravo, Erasmo; Alonso, Catalina; García, Karen; Arab, Clemente; Torres, Vicente A. Godoy; Alejandro S, Pereira; Jaime, Bustos; Galdo, Cardenas; Julio Cesar, Cuello; Mauricio A, Owen Article Oncotarget (2017)
Expression of teneurins is associated with tumor differentiation and patient survival in ovarian cancer Graumann, Rebecca; Di Capua, Gabriella A; Oyarzún, Juan E; Vásquez, Marcos A; Liao, Christine; Brañes, Jorge A; Roa, Iván; Casanello, Paola; Corvalán, Alejandro H; Owen, Gareth I; Delgado, Iris; Zangemeister-Wittke, Uwe; Ziegler, Annemarie Article PLoS One (2017)
MicroRNA-335-5p is a potential suppressor of metastasis and invasion in gastric cancer Polakovicova, I; Carrasco-Veliz, N; Bizama, C Article ISI SCOPUS Clinical Epigenetics (2017)
Reprimo tissue-specific expression pattern is conserved between zebrafish and human Figueroa, Ricardo J.; Carrasco-Avino, Gonzalo; Lange, Martin; Siekmann, Arndt F.; Robinson-Rechavi, Marc Article ISI SCOPUS PLOS ONE (2017)
Reprimo tissue-specific expression pattern is conserved between zebrafish and human Figueroa, Ricardo J; Carrasco-Avino, Gonzalo; Wichmann, Ignacio A; Lange, Martin; Owen, Gareth I; Siekmann, Arndt F; Corvalán, Alejandro H; Opazo, Juan C; Amigo, Julio D Article PLoS One (2017)
Structural and functional identification of vasculogenic mimicry in vitro Racordon, Dusan; Valdivia, Andres; Mingo, Gabriel; Santoro, Felice; Osorio, German; Alvares, Pedro; Gago-Arias, Araceli; Pinto, Mauricio P. Article ISI SCOPUS SCIENTIFIC REPORTS (2017)
The salivary peptide histatin-1 promotes endothelial cell adhesion, migration, and angiogenesis Article ISI SCOPUS FASEB Journal (2017)
Citosine-Adenine-Repeat Microsatellite of 11 beta-hydroxysteroid dehydrogenase 2 Gene in Hypertensive Children Valdivia C.; Carvajal, CA; Campino C.; Allende, F; Martinez-Aguayo, A; Baudrand, R; Vecchiola, A; Lagos, CF; Tapia-Castillo A; Aglony, M; et al. Article ISI SCOPUS AMERICAN JOURNAL OF HYPERTENSION (2016)
Citosine-Adenine-Repeat Microsatellite of 11 beta-hydroxysteroid dehydrogenase 2 Gene in Hypertensive Children Valdivia, C; Carvajal, CA; Campino, C; Allende, F; Martinez-Aguayo, A; Baudrand R; Vecchiola, A; Lagos CF; Tapia-Castillo, A; Fuentes, CA; Aglony, M; Solari, S; Kalergis, AM; Garcia, H; Owen GI; Fardella CE Article AMERICAN JOURNAL OF HYPERTENSION (2016)
Escaping Antiangiogenic Therapy: Strategies Employed by Cancer Cells Carrasco-Avino, Gonzalo Article ISI SCOPUS INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)
Escaping antioangiogenic therapy=> strategies employed by cancer cells Pinto, Mauricio; Sotomayor, Paula; Carrasco- Avino Gonzalo, Corvalan; Alejandro, Owen Article International Journal of Molecular Sciences (2016)
Evolutionary history of the reprimo tumor suppressor gene family in vertebrates with a description of a new reprimo gene lineage Wichmann, Ignacio A.; Zavala, Kattina; Hoffmann, Federico G.; Vandewege, Michael W; Corvaln, Alejandro H.; Amigo, Julio D.; Owen, Gareth I.; Opazo, Juan C. Article ISI SCOPUS GENE (2016)
Evolutionary history of the reprimo tumor suppressor gene family in vertebrates with a description of a new reprimo gene lineage. Wichmann, Ignacio A; Zavala, Kattina; Hoffmann, Federico G; Vandewege, Michael W; Corvalán, Alejandro H; Amigo, Julio D; Owen, Gareth I; Opazo, Juan C Article Gene (2016)
Modulatory Effect of 2-(4-Hydroxyphenyl)amino-1,4-naphthoquinone on Endothelial Vasodilation in Rat Aorta Gonzalez, Constanza; Cartes-Saavedra, Benjamín Article ISI SCOPUS OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)
Modulatory Effect of 2-(4-Hydroxyphenyl)amino-1,4-naphthoquinone on Endothelial Vasodilation in Rat Aorta Palacios, Javier; Cifuentes, Fredi; Valderrama, Jaime A; Benites, Julio; Ríos, David; González,Constanza; Chiong, Mario; Cartes-Saavedra, Benjamín; Lafourcade, Carlos; Wyneken, Ursula; González, Pamela; Owen, Gareth I.; Pardo, Fabián; Sobrevia, Luis; Buc Calderon, Pedro Article Oxidative Medicine and Cellular Longevity (2016)
Venlafaxine treatment after endothelin-1-induced cortical stroke modulates growth factor expression and reduces tissue damage in rats Zepeda, R.; Contreras, V; Pissani C.; Stack K.; Vargas M.; Owen, G. I.; Lazo O.M. Article ISI SCOPUS NEUROPHARMACOLOGY (2016)
Venlafaxine treatment after endothelin-1-induced cortical stroke modulates growth factor expression and reduces tissue damage in rats. Zepeda, Rodrigo; Contreras, Valentina; Pissani, Claudia; Stack, Katherine; Vargas, Macarena; Owen, Gareth I; Lazo, Oscar M; Bronfman, Francisca C Article Neuropharmacology (2016)
A snapshot of cancer in Chile: Analytical frameworks for developing a cancer policy De Jimenez La Jara J.; Bastias G.; Ferreccio, C; Moscoso, C.; Sagues S.; Cid C.; Bronstein E.; Herrera, C.; Nervi, B; Corvalán, A; et al. Article SCOPUS Biological Research (2015)
A snapshot of cancer in Chile: Analytical frameworks for developing a cancer policy. Jorge Jimenez de la Jara, Gabriel Bastias, Catterina Ferreccio, Cristian Moscoso, Sofia Sagues, Camilo Cid, Eduardo Bronstein, Cristian Herrera, Bruno Nervi, Alejandro Alejandro Corvalan, Ethel V Velasquez, Pamela Gonzalez, Enrique Castellon, Eva Bustaman Article Biological Research (2015)
Citosine-Adenine-Repeat Microsatellite of 11Î²-hydroxysteroid dehydrogenase 2 Gene in Hypertensive Children. Valdivia, Carolina; Carvajal, Cristian A; Campino, Carmen; Allende, Fidel; Martinez-Aguayo, Alejandro; Baudrand, Rene; Vecchiola, Andrea; Lagos, Carlos F; Tapia-Castillo, Alejandra; Fuentes, Cristobal A; Aglony, Marlene; Solari, Sandra; Kalergis, Alexis M; García, Hernan; Owen, Gareth I; Fardella, Carlos E Article American journal of hypertension (2015)
Enhanced caveolin-1 expression increases migration, anchorage-independent growth and invasion of endometrial adenocarcinoma cells Diaz-Valdivia, N.; Bravo, D; Huerta, H.; Henriquez, S; Gabler, F.; Vega M.; Romero, C; Calderón C; Owen, GI; Leyton, L; et al. Article ISI SCOPUS BMC Cancer (2015)
Enhanced caveolin-1 expression increases migration, anchorage-independent growth and invasion of endometrial adenocarcinoma cells. Diaz-Valdivia, Natalia; Bravo, Denisse; Huerta, Hernán; Henriquez, Soledad; Gabler, Fernando; Vega, Margarita; Romero, Carmen; Calderon, Claudia; Owen, Gareth I; Leyton, Lisette; Quest, Andrew F G Article BMC cancer (2015)
LEPTIN PROMOTES A MORE AGGRESIVE BEHAVIOR OF OVARIAN CANCER CELLS: A POTENTIAL EXPLANATION FOR A WORSE PROGNOSIS IN OBESE OVARIAN CANCER PATIENTS: IGCS-0095 Ovarian Cancer. Cuello-Fredes, M; Kato, S; Abarzúa-Catalán, L; Delpiano, A; Trigo, C; García, K; Sanhueza, C; Ibañez, C; Brañes, J; Castellon, E; Owen, G Article International journal of gynecological cancer : official journal of the International Gynecological Cancer Society (2015)
Leptin stimulates migration and invasion and maintains cancer stem-like properties in ovarian cancer cells: an explanation for poor outcomes in obese women Kato S.; Abarzua-Catalan, L; Trigo, C; Delpiano, A.; Sanhueza, C; Garcia, K; Ibañez, C; Hormazábal K.; Diaz, D.; Brañes J.; et al. Article ISI ONCOTARGET (2015)
Leptin stimulates migration and invasion and maintains cancer stem-like properties in ovarian cancer cells=> an explanation for poor outcomes in obese women. Kato S, Abarzua-Catalan L; Trigo C, Delpiano A; Sanhueza C, García K; Ibañez C, Hormazábal K; Diaz D, Brañes J; Castellón E, Bravo E; Owen G, Cuello MA. Article Oncotarget (2015)
Platelets enhance tissue factor protein and metastasis initiating cell markers, and act as chemoattractants increasing the migration of ovarian cancer cells Orellana, R; Kato S.; Erices, R.; Bravo, ML; Gonzalez, P; Oliva, B.; Cubillos S; Valdivia, A; Ibañez, C; Brañes J.; et al. Article ISI SCOPUS BMC Cancer (2015)
Platelets enhance tissue factor protein and metastasis initiating cell markers, and act as chemoattractants increasing the migration of ovarian cancer cells. Orellana R, Kato S; Erices R, Bravo ML; Gonzalez P, Oliva B; Cubillos S, Valdivia A; Ibañez C, Brañes J; Barriga MI, Bravo E; Alonso C, Bustamente E; Castellon E, Hidalgo P; Trigo C, Panes O; Pereira J, Mezzano D; Cuello MA, Owen GI. Article BMC CANCER (2015)
Progesterone regulation of tissue factor depends on MEK1/2 activation and requires the proline-rich site on progesterone receptor Bravo ML, Pinto MP; Gonzalez I, Oliva B; Kato S, Cuello MA; Lange CA, Owen GI. Article ENDOCRINE (2015)
Progesterone regulation of tissue factor depends on MEK1/2 activation and requires the proline-rich site on progesterone receptor. Bravo, Maria Loreto; Pinto, Mauricio P; Gonzalez, Ibeth; Oliva, Barbara; Kato, Sumie; Cuello, Mauricio A; Lange, Carol A; Owen, Gareth I Article Endocrine (2015)
The twisted survivin connection to angiogenesis. Sanhueza, C; Wehinger, S; Castillo Bennett, J; Valenzuela, M; Owen, G I; Quest, A F G Article Molecular cancer (2015)
2-methoxyestradiol and disorders of female reproductive tissues. Pinto, Mauricio P; Medina, Rodolfo A; Owen, Gareth I Article Hormones & cancer (2014)
High sodium intake is associated with increased glucocorticoid production, insulin resistance and metabolic syndrome Baudrand, R; Campino C.; Carvajal, CA; Olivieri, O; Guidi, G; Faccini, G; Cerda, J; Owen, G Article ISI SCOPUS CLINICAL ENDOCRINOLOGY (2014)
High sodium intake is associated with increased glucocorticoid production, insulin resistance and metabolic syndrome Baudrand R.; Campino, C; Carvajal, CA; Olivieri, O; Guidi, G; Faccini, G; Vohringer, PA; Cerda, J; Owen, G; Kalergis, AM; Fardella, CE Article CLINICAL ENDOCRINOLOGY (2014)
Identification of novel 11 beta-HSD1 inhibitors by combined ligand- and structure-based virtual screening Lagos, CF; Vecchiola, A; Allende, F; Valdivia C.; Solari, S; Campino C.; Tapia-Castillo A; Baudrand, R; Villarroel P.; Cifuentes M.; et al. Article ISI MOLECULAR AND CELLULAR ENDOCRINOLOGY (2014)
Identification of novel 11Î²-HSD1 inhibitors by combined ligand- and structure-based virtual screening. Lagos, Carlos F; Vecchiola, Andrea; Allende, Fidel; Fuentes, Cristobal A; Tichauer, Juan E; Valdivia, Carolina; Solari, Sandra; Campino, Carmen; Tapia-Castillo, Alejandra; Baudrand, Rene; Villarroel, Pia; Cifuentes, Mariana; Owen, Gareth I; Carvajal, Cristian A; Fardella, Carlos E Article Molecular and cellular endocrinology (2014)
Independent anti-angiogenic capacities of coagulation factors X and Xa. Lange, Soledad; Gonzalez, Ibeth; Pinto, Mauricio P; Arce, Maximiliano; Valenzuela, Rodrigo; Aranda, Evelyn; Elliot, Matias; Alvarez, Marjorie; Henriquez, Soledad; Velasquez, Ethel V; Orge, Felipe; Oliva, Barbara; Gonzalez, Pamela; Villalon, Manuel; Cautivo, Kelly M; Kalergis, Alexis M; Pereira, Karla; Mendoza, Camila; Saez, Claudia; Kato, Sumie; Cuello, Mauricio A; Parborell, Fernanda; Irusta, Griselda; Palma, Veronica; Allende, Miguel L; Owen, Gareth I Article Journal of cellular physiology (2014)
Independent anti-angiogenic capacities of coagulation factors X and Xa. Lange, Soledad; Gonzalez, Ibeth; Pinto, Mauricio P; Arce, Maximiliano; Valenzuela, Rodrigo; Aranda, Evelyn; Elliot, Matias; Alvarez, Marjorie; Henriquez, Soledad; Velasquez, Ethel V; Orge, Felipe; Oliva, Barbara; Gonzalez, Pamela; Villalon, Manuel; Cautivo, Kelly M; Kalergis, Alexis M; Pereira, Karla; Mendoza, Camila; Saez, Claudia; Kato, Sumie; Cuello, Mauricio A; Parborell, Fernanda; Irusta, Griselda; Palma, Veronica; Allende, Miguel L; Owen, Gareth I Article Journal of cellular physiology (2014)
LC-MS/MS Method for the Simultaneous Determination of Free Urinary Steroids Allende, F; Solari, S; Campino C.; Carvajal, C. A.; Lagos, C. F.; Vecchiola, A; Valdivia C.; Baudrand, R; Owen, G. I.; Fardella C.E. Article ISI SCOPUS CHROMATOGRAPHIA (2014)
LC-MS/MS Method for the Simultaneous Determination of Free Urinary Steroids. Allende, Fidel; Solari, Sandra; Campino, Carmen; Carvajal, Cristian A; Lagos, Carlos F; Vecchiola, Andrea; Valdivia, Carolina; Baudrand, René; Owen, Gareth I; Fardella, Carlos E Article Chromatographia (2014)
Progesterone regulation of tissue factor depends on MEK1/2 activation and requires the proline-rich site on progesterone receptor Bravo, M. L.; Pinto, M. P.; Gonzalez, I; Oliva, B.; Kato S.; Cuello, M. A.; Lange C.A.; Owen, G. I. Article ISI SCOPUS Endocrine (2014)
Antiangiogenic, antimigratory and antiinflammatory effects of 2-methoxyestradiol in zebrafish larvae Quezada M.; Alvarez, M; Pena, OA; Henriquez, S; d'Alencon, CA; Lange S.; Oliva, B.; Owen, GI Article ISI SCOPUS Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology (2013)
Antiangiogenic, antimigratory and antiinflammatory effects of 2-methoxyestradiol in zebrafish larvae. Quezada M ML.; Alvarez M; Peña OA; Henríquez S; d' Alençon CA; Lange S; Oliva B; Owen GI; Allende ML Article Comp Biochem Physiol C Toxicol Pharmacol (2013)
Breaking through an epigenetic wall Re-activation of Oct4 by KRAB-containing designer zinc finger transcription factors Juarez-Moreno, K; Erices, R.; Stolzenburg, S; Cuello-Fredes, M; Owen, GI; Qian, HL; Blancafort, P Article ISI SCOPUS Epigenetics (2013)
Breaking through an epigenetic wall: re-activation of Oct4 by KRAB-containing designer zinc finger transcription factors Juárez-Moreno K; Erices R; Beltran AS; Stolzenburg S; Cuello-Fredes M; Owen GI; Qian H; Blancafort P. Article Epigenetics (2013)
Concanavalin-A Induces Granulosa Cell Death and Inhibits FSH-Mediated Follicular Growth and Ovarian Maturation in Female Rats Rios, M.; Lizama, C; Núñez, E; Abramovich, D; Orge, F; Oliva, B.; Orellana, R; Villalón, M; Tesone, M; Rokka, A; et al. Article ISI SCOPUS ENDOCRINOLOGY (2013)
Concanavalin-A induces granulosa cell death and inhibits FSH-mediated follicular growth and ovarian maturation in female rats. Velasquez EV, Ríos M; Ortiz ME, Lizama C; Nuñez E, Abramovich D; Orge F, Oliva B; Orellana R, Villalon M; Moreno RD, Tesone M; Rokka A, Corthals G; Croxatto HB, Parborell F Article ENDOCRINOLOGY (2013)
Different effects of progesterone and estradiol on chimeric and wild type aldosterone synthase in vitro Vecchiola, A; Lagos CF; Fuentes, CA; Allende, F; Campino, C; Valdivia, C; Tapia-Castillo, A; Ogishima, T; Mukai, K; Owen, G; Solari, S; Carvajal, CA; Fardella CE Article REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY (2013)
Different effects of progesterone and estradiol on chimeric and wild type aldosterone synthase in vitro Vecchiola, A; Lagos, CF; Allende, F; Campino C.; Valdivia C.; Tapia-Castillo A; Ogishima, T; Mukai, K; Owen, G; Solari, S; et al. Article ISI SCOPUS Reproductive Biology and Endocrinology (2013)
Efectos de las estatinas en cáncer: Potencial rol en terapéutica y prevención Mauricio Cuello; Sumie Kato; Daniela Díaz; Gareth I. Owen; Cuello-Fredes M Article Revista Medica de Chile (2013)
In vitro cell response to chemotherapeutic agents, to personalize ovarian cancer treatment. Report of two cases Ibañez, C; Garrido, M; Medina, L; Kato S.; Bravo, ML; Gonzalez, P; Oliva, B.; Pizarro, J; Bustamante, E; Brañes J.; et al. Article ISI REVISTA MEDICA DE CHILE (2013)
Involvement of the ANGPTs/Tie-2 system in ovarian hyperstimulation syndrome (OHSS) Scotti L; Abramovich D; Pascuali N; de Zúñiga I; Oubiña A; Lange S; Owen GI; Tesone M; Parborell F; F.Kopcow L Article Molecular and Cellular Endocrinology (2013)
Involvement of the ANGPTs/Tie-2 system in ovarian hyperstimulation syndrome (OHSS) Scotti L.; Abramovich, D; Pascuali, N; de Zuniga, I; Oubina, A; Kopcow, L; Lange S.; Owen, G; Tesone, M; Parborell, F Article ISI SCOPUS Molecular and Cellular Endocrinology (2013)
Metformin, at Concentrations Corresponding to the Treatment of Diabetes, Potentiates the Cytotoxic Effects of Carboplatin in Cultures of Ovarian Cancer Cells Erices, R.; Bravo, ML; Gonzalez, P; Oliva, B.; Racordon D; Garrido, M; Ibañez, C; Kato S.; Brañes J.; Pizarro, J; et al. Article ISI SCOPUS Reproductive Sciences (2013)
Metformin, at concentrations corresponding to the treatment of diabetes, potentiates the cytotoxic effects of carboplatin in cultures of ovarian cancer cells. Erices R, Bravo ML; Gonzalez P, Oliva B; Racordon D, Garrido M; Ibañez C, Kato S; Brañes J, Pizarro J; Barriga MI, Barra A; Bravo E, Alonso C; Bustamente E, Cuello MA Article Reproductive Sciences (2013)
Paclitaxel-PHBV nanoparticles and their toxicity to endometrial and primary ovarian cancer cells Vilos C.; Morales, FA; Solar, PA; Herrera, NS; Gonzalez-Nilo, FD; Aguayo, DA; Mendoza HL; Comer, J.; Bravo, ML; Kato S.; et al. Article ISI SCOPUS Biomaterials (2013)
Paclitaxel-PHBV nanoparticles and their toxicity to endometrial and primary ovarian cancer cells Vilos C.; Morales, FA; Solar, PA; Herrera, NS; Gonzalez-Nilo, FD; Aguayo, DA; Mendoza, HL; Comer, J; Bravo, ML; Gonzalez, PA; Kato S.; Cuello, MA; Alonso C.; Bravo, EJ; Bustamante, EI; Owen GI; Velasquez, LA Article BIOMATERIALS (2013)
Potencial Herramienta en la personalización del tratamiento oncológico. Carolina Ibáñez; Marcelo Garrido; Lidia Medina; Sumie Kato; María Loreto Bravo; Pamela Gonzalez; Barbara Oliva; Javier Pizarro; Eva Bustamante; Jorge Brañes; Mauricio Cuello; Gareth I. Owen Article Revista Médica de Chile, (2013)
11 beta-Hydroxysteroid Dehydrogenase Type 2 Polymorphisms and Activity in a Chilean Essential Hypertensive and Normotensive Cohort Campino C.; Quinteros, H; Owen, G. I.; Carvajal, C. A.; Morales, M; Olivieri, O; Guidi, G; Faccini, G; Pasini, F; Baudrand, R; et al. Article ISI SCOPUS American Journal of Hypertension (2012)
11β-hydroxysteroid dehydrogenase type 2 polymorphisms and activity in a chilean essential hypertensive and normotensive cohort. Campino C; Quinteros H; Owen GI; Carvajal CA; Morales M; Olivieri O; Guidi G; Faccini G; Pasini F; Baudrand R; Padilla O; Valdivia C; Thichauer J; Lagos CF; Kalergis AM; Fardella CE Article American Journal of Hypertension (2012)
PPAR alpha and PPAR gamma regulate the nucleoside transporter hENT1 Racordon D; Bravo, L.; Owen, G. I.; Bronfman M.L. Article ISI SCOPUS Biochemical and Biophysical Research Communications (2012)
PPARα and PPARγ regulate the nucleoside transporter hENT1. Montero TD; Racordon D; Bravo ML .; Owen GI; Bronfman ML; Leisewitz AV Article Biochemical and Biophysical Research Communications (2012)
Progesterone promotes focal adhesion formation and migration in breast cancer cells through induction of protease-activated receptor-1 Díaz J.; Aranda, E; Henríquez S.; Quezada M.; Espinoza E; Bravo M.L.; Oliva B.; Lange, S; Villalón M.; Jones M.; Brosens J.J.; Kato S.; Cuello M.A.; Knutson T.P.; Lange C.A.; Leyton L.; Owen G.I. Article JOURNAL OF ENDOCRINOLOGY (2012)
Progesterone promotes focal adhesion formation and migration in breast cancer cells through induction of protease-activated receptor-1 Diaz, J; Aranda, E; Henriquez, S; Quezada M.; Espinoza E.; Bravo, M. L.; Oliva, B.; Lange S.; Villalón, M; Jones, M; et al. Article ISI SCOPUS Journal of Endocrinology (2012)
The identification of two subgroups of obese women with differing endometrial proliferation levels: potential consequences in the development of endometrial cancer Villavicencio, A; Aguilar G.; Acua J.; Gabler F.; Soto E.; Gaete F; Pealoza P.; Celis, M; Owen G.I. Article INTERNATIONAL JOURNAL OF OBESITY (2012)
The identification of two subgroups of obese women with differing endometrial proliferation levels: potential consequences in the development of endometrial cancer Villavicencio A.; Aguilar, G; Acua J.; Gabler, F.; Soto, E; Gaete, F; Pealoza P.; Celis, M.; Owen, G. I. Article ISI SCOPUS International Journal of Obesity (2012)
Increased urinary glucocorticoid metabolites are associated with metabolic syndrome, hypoadiponectinemia, insulin resistance and β cell dysfunction. Baudrand R; Campino C; Carvajal CA; Olivieri O; Guidi G; Faccini G; Sateler J; Cornejo J; Martin BS; Dominguez JM; Cerda J,; Mosso LM; Owen GI; Kalergis AM; Fardella CE Article Steroids (2011)
Increased urinary glucocorticoid metabolites are associated with metabolic syndrome, hypoadiponectinemia, insulin resistance and beta cell dysfunction Baudrand, R; Campino C.; Carvajal, CA; Olivieri, O; Guidi, G; Faccini, G; Sateler, J; Cornejo, J; Martin, BS; Domínguez JM; et al. Article ISI SCOPUS Steroids (2011)
Progesterone Utilizes Distinct Membrane Pools of Tissue Factor to Increase Coagulation and Invasion and These Effects are Inhibited by TFPI Henríquez S.; Calderón C.; Quezada M.; Oliva B.; Bravo, ML; Aranda, E; Kato S.; Cuello, MA; Gutiérrez J.; Quest, AFG; Owen GI Article JOURNAL OF CELLULAR PHYSIOLOGY (2011)
Progesterone Utilizes Distinct Membrane Pools of Tissue Factor to Increase Coagulation and Invasion and These Effects are Inhibited by TFPI Henriquez, S; Calderón C; Quezada M.; Oliva, B.; Bravo, ML; Aranda, E; Kato S.; Cuello, MA; Gutierrez, J.; Quest, AFG; et al. Article ISI SCOPUS Journal of Cellular Physiology (2011)
11 beta-hydroxysteroid dehydrogenase type-2 and type-1 (11 beta-HSD2 and 11 beta-HSD1) and 5 beta-reductase activities in the pathogenia of essential hypertension Campino C.; Carvajal, CA; Cornejo, J; Martin, BS; Olivieri, O; Guidi, G; Faccini, G; Pasini, F; Sateler, J; Baudrand, R; et al. Article ISI SCOPUS Endocrine (2010)
2-methoxyestradiol inhibits progesterone mediated Tissue Factor expression and activity in breast cancer cells. Quezada M; Diaz J; Henriquez S; Bravo ML; Aranda E; Oliva B; Villalon M; Kato S; Cuello M.A; Brosens J.J; Lange CA; Owen GI Article Hormones and Cancer (2010)
2-Methoxyestradiol inhibits progesterone-dependent tissue factor expression and activity in breast cancer cells Quezada M.; Diaz, J; Henriquez, S; Bravo, M. L.; Aranda, E; Oliva, B.; Villalón, M; Owen, G. I.; Kato S.; Cuello, M. A.; et al. Article SCOPUS Hormones and Cancer (2010)
Lipophilic but not hydrophilic statins selectively induce cell death in gynaecological cancers expressing high levels of HMGCoA reductase Kato S.; Smalley S.; Sadarangani, A; Chen-Lin, K; Oliva, B.; Brañes J.; Carvajal, J.; Gejman, R; Owen, GI; Cuello, M. Article ISI SCOPUS Journal of Cellular and Molecular Medicine (2010)
Lipophilic but not hydrophilic statins selectively induce cell death in gynecological cancers expressing high levels of HMGCoA reductase. Kato S; Smalley S; Sadarangani A; Chen-Lin K; Oliva B; Brañes J; Carvajal J; Gejman R; Owen GI; Cuello M Article Journal of Cellular and Molecular Medicine (2010)
A semi-quantitative assay to screen for angiogenic compounds and compounds with angiogenic potential using the EA.hy926 endothelial cell line Aranda E; Owen G.I Article Biological Research (2009)
A semi-quantitative assay to screen for angiogenic compounds and compounds with angiogenic potential using the EA.hy926 endothelial cell line Aranda, E; Owen, GI Article ISI SCIELO SCOPUS BIOLOGICAL RESEARCH (2009)
Glucose Transporters in Sex Steroid Hormone Related Cancer Francisco Nualart; María de los Angeles García; Rodolfo A. Medina; Gareth I. Owen Article Current Vascular Pharmacology (2009)
2-Methoxyestradiol mediates apoptosis through caspase-dependent and independent mechanisms in ovarian cancer cells but not in normal counterparts. Kato S; Sadarangani A; Lange MS; Jaque MP; Delpiano AM; Brañes J; Carvajal J; Lipkowitz S; Owen GI; Cuello MA Article Reproductive Sciences (2008)
2-Methoxyestradiol Mediates Apoptosis Through Caspase-Dependent and Independent Mechanisms in Ovarian Cancer Cells But Not in Normal Counterparts Kato S.; Sadarangani, A; Lange S.; Vargas M.; Brañes J.; Carvajal, J.; Lipkowitz, S; Owen, GI; Cuello, MA Article ISI SCOPUS REPRODUCTIVE SCIENCES (2008)
Characterization and phenotypic variation with passage number of cultured human endometrial adenocarcinoma cells Kato S.; Espinoza, N; Lange S.; Villalón, M; Cuello, M.; Owen, GI Article ISI SCOPUS TISSUE CELL (2008)
Establishment and characterization through passage number of human endometrial cancer cells in culture Kato S; Espinoza N; Lange S; Cuello M; Villalon M; Owen GI Article Tissue and Cell (2008)
Possible pathogenetic role of 11 beta-hydroxysteroid dehydrogenase type 1 (11betaHSD1) gene polymorphisms in arterial hypertension Morales MA; Carvajal CA; Ortiz E; Mosso LM; Artigas RA; Owen GI; Fardella CE Article Revista medica de Chile (2008)
Possible pathogenetic role of 11 beta-hydroxysteroid dehydrogenase type 1 (11 beta HSD1) gene polymorphisms in arterial hypertension Carvajal, CA; Ortiz, E; Mosso, LM; Artigas, RA; Owen, GI Article ISI REVISTA MEDICA DE CHILE (2008)
Regiones polimórficas del gen 11ß-hidroxiesteroide deshidrogenasa tipo 1 (11ßHSD1) en hipertensión arterial esencial: Posible rol etiopatogénico Morales, Mauricio A; Carvajal, Cristian A.; Ortiz, Eugenia; Mosso, Lorena M; Artigas, Rocío A; Owen, Gareth I.; Fardella, Carlos E. Article SCIELO REVISTA MEDICA DE CHILE (2008)
Regulation of GLUT3 and glucose uptake by the cAMP signalling pathway in the breast cancer cell line ZR-75 Meneses, AM; Kato S.; Pint M.; Jaque, MP; Lizama I; Garcia, MDLA; Nualart, F.; Owen, GI Article ISI SCOPUS JOURNAL OF CELLULAR PHYSIOLOGY (2008)
Regulation of GLUT3 and glucose uptake by the cAMP signalling pathway in the breast cancer cell line ZR-75. Meneses AM; Medina RA; Kato S; Pinto M; Jaque MP; Lizama I; Garcia MD; Nualart F; Owen GI Article Journal of Cellular Physiology (2008)
Retinoblastoma protein and the leukemia-associated PLZF transcription factor interact to repress target gene promoters Petrie K; Guidez F; Zhu J; Howell L; Owen GI; Chew YP; Parks S; Waxman S; Licht J; Mittnacht S; Zelent A Article Oncogene (2008)
Retinoblastoma protein and the leukemia-associated PLZF transcription factor interact to repress target gene promoters Petrie, K; Guidez, F; Zhu, J; Howell, L; Owen, G; Chew, YP; Parks, S; Waxman, S; Licht, J; Mittnacht, S; et al. Article ISI SCOPUS ONCOGENE (2008)
The oestrogen metabolite 2-methoxyoestradiol alone or in combination with tumour necrosis factor-related apoptosis-inducing ligand mediates apoptosis in cancerous but not healthy cells of the human endometrium Kato S.; Sadarangani, A; Lange S.; Villalón, M; Brañes J.; Brosens, JJ; Owen, GI; Cuello, M. Article ISI SCOPUS ENDOCRINE-RELATED CANCER (2007)
TRAIL mediates apoptosis in cancerous but not normal primary cultured cells of the human reproductive tract Sadarangani, A; Kato S.; Espinoza, N; Lange S.; Llados, C; Espinosa,M; Villalón, M; Lipkowitz, S; Cuello, M.; Owen, GI Article ISI SCOPUS APOPTOSIS (2007)
In vivo and in vitro estrogenic and progestagenic actions of Tibolone Sadarangani, A; Salgado, AN; Kato S.; Pinto, M; Carvajal A.; Monso, C; Owen, GI; Vigil, P Article ISI SCIELO SCOPUS BIOLOGICAL RESEARCH (2005)
Progesterone increases tissue factor gene expression, procoagulant activity, and invasion in the breast cancer cell line ZR-75-1 Kato S.; Pinto, M; Carvajal A.; Espinoza, N; Monso, C; Sadarangani, A; Villalón, M; Brosens, JJ; White, JO; Richer, JK; et al. Article ISI SCOPUS JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2005)
Progesterone pre-treatment potentiates EGF pathway signaling in the breast cancer cell line ZR-75 Carvajal A.; Espinoza, N; Kato S.; Pinto, M; Sadarangani, A; Monso, C; Aranda, E; Villalón, M; Richer, JK; Horwitz, KB; et al. Article ISI SCOPUS BREAST CANCER RESEARCH AND TREATMENT (2005)
Tissue factor is regulated by epidermal growth factor in normal and malignant human endometrial epithelial cells Kato S.; Pinto, M; Carvajal A.; Espinoza, N; Monso, C; Bravo, L.; Villalón, M; Cuello, M.; Suenaga, A; Brosens, JJ; et al. Article ISI SCOPUS THROMBOSIS AND HAEMOSTASIS (2005)
Differential regulation of glucose transporter expression by estrogen and progesterone in Ishikawa endometrial cancer cells Meneses, AM; Vera, JC; Guzmán, C; Nualart, F.; Rodriguez,F; Garcia, MD; Kato S.; Espinoza, N; Monso, C; Carvajal A.; et al. Article ISI SCOPUS JOURNAL OF ENDOCRINOLOGY (2004)
Estrogen and progesterone up-regulate glucose transporter expression in ZR-75-1 human breast cancer cells Meneses, AM; Vera, JC; Guzmán, C; Nualart, F.; Astuya A.; Garcia, MD; Kato S.; Carvajal A.; Pinto, M; Owen, GI Article ISI SCOPUS ENDOCRINOLOGY (2003)
Origins and evolutionary diversification of the nuclear receptor superfamily Zelent, A Article ISI CELLULAR AND MOLECULAR LIFE SCIENCES (2000)
Convergence of progesterone with growth factor and cytokine signaling in breast cancer - Progesterone receptors regulate signal transducers and activators of transcription expression and activity Manning, NG; Horwitz, KB Article ISI JOURNAL OF BIOLOGICAL CHEMISTRY (1998)
Progesterone regulates transcription of the p21(WAF1) cyclin-dependent kinase inhibitor gene through Sp1 and CBP/p300 Richer, JK; Tung, L; Takimoto, G; Horwitz, KB Article ISI JOURNAL OF BIOLOGICAL CHEMISTRY (1998)
Differential expression of the A and B isoforms of progesterone receptor in human endometrial cancer cells - Only progesterone receptor B is induced by estrogen and associated with strong transcriptional activation Leslie, KK; Kumar, NS; Horwitz, KB; Bulletti, C; deZiegler, D; Guller, S; Levitz, M Article ISI ANNALS OF THE NEW YORK ACADEMY OF SCIENCES (1997)


Leptin induces an IL-6 mediated interaction between macrophages and ovarian cancer cells that prompted invasiveness and migration Kato S.; Abarzua-Catalan, L; Solar-Costabal, I; Garcia, K; Brañes J.; Owen, GI; Cuello, MA Abstract ISI CANCER RESEARCH (2015)
MATERNAL OBESITY IMPAIRS MIGRATION OF FETAL ENDOTHELIUM INVOLVING ENDOPLASMIC RETICULUM STRESS Villalobos-Labra, R; Sáez PJ; Gonzalez, I; Westermeier, F; Sobrevia, L; Casanello, P; Owen, GI; Farias-Jofre, M Abstract ISI PLACENTA (2015)
2-METHOXYESTRADIOL REVERTS EPITHELIAL MESENCHYMAL TRANSITION IN OVARIAN CANCER-INITIATING CELLS REDUCING THEIR INVASIVE CAPABILITY AND SENSITIZING THEM TO CHEMOTHERAPY Cuello-Fredes, M; Hormazábal K.; Kato S.; Abarzua-Catalan, L; Brañes J.; Barriga, M; Castellón E.; Bravo, E; Le Cerf P.; Owen, GI Abstract ISI INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER (2014)
Ovarian cancer cells treated with leptin contribute with a pro-tumoral phenotype in macrophages in vitro Abarzua-Catalan, L; Kato S.; Owen, GI; Cuello, MA Abstract ISI EUROPEAN JOURNAL OF CANCER (2014)
Personalized cancer therapy for ovarian cancer patients Aguilar, A; Valdiviezo, PI; Ibañez, C; Bravo, ML; Gonzales, P; Kato S.; Garrido, M; Brañes J.; Pizarro, J; Leon, H; et al. Abstract ISI JOURNAL OF CLINICAL ONCOLOGY (2014)
Platelet interaction induces Tissue Factor and a pro-metastatic phenotype in ovarian cancer cells Orellana, RF; Oliva, B.; Kato S.; Bravo, L.; Gonzalez, P; Panes O.; Mezzano D.; Cuello, M.; Owen, G Abstract ISI CANCER RESEARCH (2014)
PROSPECTIVE OBSERVATIONAL STUDY TO ASSESS THE INFLUENCE OF OVERWEIGHT AND OBESITY OVER SURVIVAL FOR PATIENTS WITH OVARIAN CANCER. Sanhueza, C; Garcia, K; Cuello, M.; Brañes J.; Owen, G; Kato S.; Bravo, M; Ibañez, C Abstract ISI INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER (2014)
Simvastatin modifies the expression of stemness and epithelial-mesenchymal transition (EMT) markers in ovarian cancer-initiating cells resulting in decreased cell migration Kato S.; Abarzua, L.; Hormazábal K.; Delpiano, A.; Bravo, ML; Orellana, R; Brañes J.; Castellón E.; Cuello-Fredes, M; Owen, GI Abstract ISI EUROPEAN JOURNAL OF CANCER (2014)
2-Methoxyestradiol induces differentiation of epithelial ovarian cancer-initiating cells sensitizing them to chemotherapy. Cuello, MA; Kato S.; Hormazábal K.; Abarzua, L.; Bravo, L.; Barriga, I; Barrena, N; Brañes J.; Bravo, E; Gejman, R; et al. Abstract ISI CANCER RESEARCH (2013)
Combining chemotherapy and targeted therapies against resistance and recurrence in ovarian cancer Fernández-Ramires, R; Herreros E.; Vilos C.; Bravo, ML; Otero, C.; Morales, S; Velasquez L.; Owen, G Abstract ISI FEBS JOURNAL (2013)
In situ estrogen metabolism in subgroups of obese women with differing potential risk for developing endometrial cancer Villavicencio A.; López, V; Medina, E; Barahona, C; Peñaloza, P.; Gaete E.; Albornoz, C.; Castro, F.; Celis, M.; Owen, G Abstract ISI EUROPEAN JOURNAL OF CANCER (2013)
PERSONALIZED CANCER THERAPY FOR OVARIAN CANCER PATIENTS. Ibañez, C; Bravo, ML; Owen, GI; Gonzalez, P; Cuello, MA; Kato S.; Brañes J.; Pizarro, J; Barrena, N; Jimenez, P; et al. Abstract ISI INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER (2013)
Simvastatin Inhibits Leptin-activated Signaling Pathways That Promote Migration and Invasiveness of Ovarian Cancer Cells Cuello-Fredes, M; Kato S.; Diaz, D.; Vecchiola, A; Brañes J.; Gejman, R; Owen, GI Abstract ISI EUROPEAN JOURNAL OF CANCER (2012)
A Novel Polymorphism in 11 beta-Hydroxysteroid Dehydrogenase Type 2 Gene (HSD11B2) Is Associated with High Urinary Excretion of Tetrahydro-11-Deoxycortisol (THS) in Essential Hypertensive Patients. Campino C.; Quinteros, H; Carvajal, C; Morales, M; Olivieri, O; Guidi, G; Faccini, G; Passini, F; Sateler, J; Baudrand, R; et al. Abstract ISI ENDOCRINE REVIEWS (2010)
Central Obesity and the Metabolic Syndrome Are Associated with Portal and Not Systemic Hypercortisolism Supported by the Raise of Urinary Corticosteroid Metabolites Baudrand, R; Campino C.; Carvajal, CA; Olivieri, O; Guidi, G; Faccini, G; Pasini, F; Sateler, J; Cornejo, J; San Martín, B.; et al. Abstract ISI ENDOCRINE REVIEWS (2010)
Leptin increases the invasiveness and angiogenesis-mediated but not proliferation in human epithelial ovarian cancer cells Cuello, MA; Kato S.; Diaz, D.; Owen, GI Abstract ISI EJC SUPPLEMENTS (2010)
Progesterone regulation of breast cancer cell coagulative and invasive potential is dependent on the distinct membrane localization of tissue factor Owen, G; Bravo, ML; Quezada M.; Henriquez, S Abstract ISI EJC SUPPLEMENTS (2010)
Visceral Hypercortisolism Observed in Central Obesity and Metabolic Syndrome Is Associated with Insulin Resistance and Beta Cell Dysfunction. Baudrand, R; Campino C.; Carvajal, CA; Olivieri, O; Guidi, G; Faccini, G; Pasini, F; Sateler, J; Cornejo, J; Martin, BS; et al. Abstract ISI ENDOCRINE REVIEWS (2010)
Establishment and characterization of a human uterine sarcoma cell line sensitive to TNF-related apoptosis inducing ligand plus doxorubicin. Cuello, MA; Kato S.; Sadarangani, A; Owen, GI Abstract ISI REPRODUCTIVE SCIENCES (2008)
Retinoblastoma protein and the leukemia-associated PLZF transcription factor interact to repress target gene promoters. Petrie, KR; Guidez, F; Zhu, J; Owen, G; Chew, YP; Waxman, S; Licht, JD; Mittnacht, S; Arthur, Z Abstract ISI BLOOD (2007)
2-methoxiestradiol induces apoptosis in gynecologic cancer cells but not in normal cell lines established from reproductive tissues. Cuello, MA; Kato S.; Sadarangani, A; Espinoza, N; Lange S.; Villalón, M; Owen, G Abstract ISI JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION (2006)
2-Methoxyestradiol induces apoptosis in ovarian cancer cells but not in normal cells Kato S.; Sadarangani, A; Espinoza, N; Lange S.; Owen, G; Cuello, M. Abstract ISI PLACENTA (2006)
Characterization and phenotypic variation with passage number of cultured human endometrial adenocarcinoma cells. Kato S.; Cuello, MAA; Espinoza, N; Lange S.; Sadarangani, A; Owen, G Abstract ISI JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION (2006)
TNF-related apoptosis inducing ligand (TRAIL) induces apoptosis in endometrial cancer cells but not in normal cells. Cuello, MA; Sadarangani, A; Kato S.; Espinoza, N; Owen, GI Abstract ISI JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION (2005)


Nuclear Receptor Genes: Evolution Saez, JP; Lange S.; Perez-Acle, T; Owen, GI BookSection (2010)


Potencial herramienta en la personalización del tratamiento oncológico: Casos clínicos Ibáñez C, Carolina; Garrido S, Marcelo; Medina, Lidia; Kato, Sumie; Bravo, María Loreto; Gonzalez, Pamela; Oliva, Barbara; Pizarro, Javier; Bustamante, Eva; Branes, Jorge; et al. CaseReport SCIELO SCOPUS REVISTA MEDICA DE CHILE (2013)


The Chilean Gastric Cancer Task Force: an update of results Koch, Erica; Garrido, Marcelo ConferencePoster (2018)
Coagulation factor Xa promotes melanoma metastasis Arce, Maximiliano; Galleguillos, Macarena; Quest, andrew ConferencePoster (2017)
Mímica vasculogénica en cáncer de ovario ConferencePoster (2017)
Vasculogenic mimicry: an alternative model of tumour irrigation ConferencePoster (2017)


Cancer's new Achilles' heel? Editorial ISI SCOPUS ONCOTARGET (2017)


Author Correction: The Reprimo gene family member, reprimo-like (rprml), is required for blood development in embryonic zebrafish (Scientific Reports, (2019), 9, 1, (7131), 10.1038/s41598-019-43436-8) Stanic K.; Figueroa R.J.; Retamal P.A.; Owen, G. I. Errata ISI SCOPUS SCIENTIFIC REPORTS (2020)
TRAIL mediates apoptosis in cancerous but not normal primary cultured cells of the human reproductive tract (vol 12, pg 73, 2007) Sadarangani, A; Kato S.; Espinoza, N; Lange S.; Llados, C; Espinosa,M; Villalón, M; Lipkowitz, S; Cuello, M.; Owen, GI Errata ISI APOPTOSIS (2007)


Methods to identify inhibitors of 11β-HSD1 Vecchiola, Andrea; Campino, Maria; Solari, Sandra; Allende, Fidel; Fardella, Carlos Patent
Process for obtaining cell culture to perform personalized medicine Kato, Sumie; Cuello, Mauricio Patent
Use of a FSH fraction in the control of cell proliferation Sadarangani, Anil; Corxatto, Hector Patent
Use of coagulation Factor X and Xa in the treatment of angiogenic disorders Lange, Maria; Aranda, Evelyn Patent


Mechanism of resistance to immunotherapy based on checkpoint inhibitors in metastatic gastric cancer Garrido, Marcelo Proyecto (2018)
THE EXTRACELLULAR MATRIX PROMOTES THE PROCESS OF VASCULOGENIC MIMICRY AND THUS DELIVERS AN ADVANTAGE TO OVARIAN CANCER PROGRESSION. Sotomayor, Paula Proyecto (2018)
BMS Proyecto (2017)
Estudio de la relación entre los parámetros de difusión obtenida mediante imágenes de resonancia magnética (DW RM) y el número de Células clonogénicas en un tumor o muestra Sanchez, Beatriz Proyecto (2016)
Estudio De La Relación Entre Los Parámetros De Difusión Obtenidos Mediante Imágenes De Resonancia Magnética (Dwrm) Y El Número De Células Clonogénicas En Un Tumor O Muestra Vicerrectoria PUC Interdisciplinaria (II15058) Proyecto 2016-2018 Coinvestigador(a)
Instituto Milenio de Inmunología e Inmunoterapia PIA (IMII P09/0) Proyecto 2016-2021 Coinvestigador(a)
Advanced Center for Chronic Diseases (ACCDIS) Proyecto (2014)
Consorcio Tecnólogico en Biomedicina aplicada para el desarrollo de nuevas estrategias de prevención, diagnóstico y tratamiento; P6: Terapia oncológica personalizada: desarrollo de un servicio de diagnóstico para predecir individualmente en cada paciente cual tratamiento de quimioterapia entregará una respuesta clínica favorable en cáncer de ovario y cáncer del tracto gastrointestinal Proyecto (2014)
Modulation of the process of Angiogenesis by Coagulation Factor X FONDECYT (1140970) Proyecto 2014-2018 Director(a)
MODULATION OF THE PROCESS OF ANGIOGENESIS BY COAGULATION FACTOR X Cuello, Mauricio; Velasquez, Ethel; Valenzuela, Rodrigo Proyecto (2014)
TERAPIA ONCOLÓGICA PERSONALIZADA PIA (13CTI21526) Proyecto 2014-2017 Inv. Principal
Advanced Center for Chronic Diseases (ACCDiS) FONDAP (15130011) Proyecto 2013-2018 Coinvestigador(a)
Ensayo de medicina personalizada para pacientes con cáncer de ovario y su expansión como servicio clínico nacional e internacional Proyecto (2013)
Ensayo de medicina personalizada para pacientes con cáncer de ovario y su expansión como servicio clínico nacional e internacional PIA (13IDL2-186) Proyecto 2013-2016 Inv. Principal
Identificación y desarrollo de inhibidores de la enzima 11beta-HSD1 para el tratamiento de la hipertensión arterial y el síndrome metabólico FONDEF (CA12I10150) Proyecto 2013-2016 Coinvestigador(a)
Effects of statins in the maintenance, differentiation and drug sensitivity of cancer-initiating cells in ovarian cancer FONDECYT (1120292) Proyecto 2012-2015 Coinvestigador(a)
Primary aldosteronism and HSD11B2 enzyme activity defects in pediatric population and its empact on the generation of endotelial injury, oxidative stress and arterial hypertension Fardella, Carlos; Aglony, Marlene; Campino, Maria Proyecto (2011)
The identification of subgroups of obese women with differing potential risk for developing endometrial carcinoma FONDECYT (1110232) Proyecto 2011-2014 Coinvestigador(a)
The identification of subgroups of obese women with differing potential risk for developming endometrial carcinoma Villavicencio, Alejandra Proyecto (2011)
Generación y desarrollo de nuevos fármacos para el tratamiento de cánceres dependientes de EGFR FONDEF (D09I1104) Proyecto 2010-2013 Coinvestigador(a)
Generación y desarrollo de nuevos fármacos para el tratamiento de cánceres dependientes del EGFR Gonzalez de la Rosa, Alfonso Proyecto (2010)
Primary aldosteronism and HSD11B2 enzyme activity defects in pediatric population and its impact on the generation of endothelial injury, oxidative stress and arterial FONDECYT (1100356) Proyecto 2010-2013 Coinvestigador(a)
STUDY OF A NOVEL HUMAN FOLLICLE STIMULATING HORMONE (FSH) VARIANT: ELUCIDATION OF THE PHYSIOLOGICAL ROLE AND PATHOLOGICAL IMPLICATIONS Cuello, Mauricio; Villalon, Manuel Proyecto (2010)
Study of a novel human follicle stimulating hormone (FSH) variant=> Elucidation of the physiological role and pathological implications. FONDECYT (1100870) Proyecto 2010-2014 Inv. Principal
Nuevo test Diagnóstico molecular para identificar causas de hipertensión arterial esencial con y sin síndrome metabólico Fardella, Carlos Proyecto (2009)
Nuevo test diagnóstico molecular para identificar causas de hipertensión arterial esencial con y sin síndrome metabólico FONDEF (D08I1087) Proyecto 2009-2012 Coinvestigador(a)
Efectos de las estatinas en la capacidad metastásica y la sensibilidad a agentes inductores de apoptosis en el cáncer de ovario Cuello, Mauricio; Gejman, Roger; Kato, Sumie Proyecto (2008)
Efectos de las estatinas en la capacidad metastásica y la sensibilidad a agentes inductores de apoptosis en el cáncer de ovario FONDECYT (1080163) Proyecto 2008-2012 Coinvestigador(a)
Terapia Oncológica Personalizada (TOP): Desarrollo de métodos de diagnóstico molecular para ayudar en la elección del tratamiento más adecuado para cada paciente con cáncer Proyecto (2008)
Terapia Oncológica Personalizada (TOP)=> Desarrollo de métodos de diagnóstico molecular para ayudar en la elección del tratamiento más adecuado para cada paciente con cáncer. PIA (CTU06) Proyecto 2008-2013 Inv. Responsable
Desarrollo de una nueva droga anti tumoral para el tratamiento de cánceres del tracto reproductivo femenino Proyecto (2007)
Desarrollo de una nueva droga anti-tumoral para el tratamiento de cánceres del tracto reproductivo femenino FONDEF (DO6I1017) Proyecto 2007-2011 Director(a)
Evaluación clínico- molecular del rol de las deshidrogenasas tipo 1 y 2 (11BHSD1 y 11BHSD2) en la génesis de la hipertensión arterial hiporrennemica Fardella, Carlos; Mosso, Lorena Proyecto (2007)
Evaluación clínico-molecular del rol de las deshidrogenasas tipo 1 y 2 (11BHSD1 y 11BHSD2) en la génesis de la hipertensión arterial hiporrennemica FONDECYT (1070876) Proyecto 2007-2010 Coinvestigador(a)
Elucidation of the regulation and pathophysiological actions of tissue factor in breast and endometrial cancer. FONDECYT (1060495) Proyecto 2006-2010 Inv. Principal
ELUCIDATION OF THE REGULATION AND PATHOPHYSIOLOGICAL ACTIONS OF TISSUE FACTOR IN BREAST AND ENDOMETRIAL CANCER. Villalon, Manuel Proyecto (2006)
Differential Regulation of Tissue Factor expression in breast and endometrial cells The wellcome Trust, International Collaboration Grant, GR071469 (GR071469) Proyecto 2003-2006 Inv. Principal
Differential regulation of Tissue Factor expression in breast and endometrial cells Proyecto (2003)
PAPEL PARADOJICO DE LA PROGESTERONA EN LA MAMA Y EL ENDOMETRIO UTERINO: ELUCIDACION DE LA "CROSS-TALK" ENTRE LA PROGESTERONA Y LA VIA DE SENAL DEL EGF Owen, Gareth Ivor; Villalon, Manuel Proyecto (2003)
Papel paradójico de la progesterona en la mama y el endometrio uterino=> Elucidación de la "Cross-Talk" entre la progesterona y la vía de señal del EGF. FONDECYT (1020715) Proyecto 2002-2006 Inv. Principal
Elucidation of the differential regulation of breast and endometrial cells by oestrogen and progesterone and their interaction with the EGF signal transduction pathway. DIPUC Proyecto 2001-2002 Inv. Responsable
Equipment Grant=> To establish and maintain a cell line model system of the breast and endometrium. Fundacion Andes Proyecto 2001-2002 Inv. Responsable
Respuesta de Tibolona (Tinox) en células de mama y útero Gynaepharm CFR Proyecto 2001-2002 Inv. Responsable
Extending palliative care reach from secondary to primary health care level and from urban to rural communities Perez-Cruz, Pedro Proyecto (0)


Advances towards the use of gastrointestinal tumor patient-derived organoids as a therapeutic decision-making tool Leal, Pamela Review ISI BIOLOGICAL RESEARCH (2023)
The Reprimo Gene Family: A Novel Gene Lineage in Gastric Cancer with Tumor Suppressive Properties Amigo, JD; Jorquera, R; Wichmann, IA; Garcia-Bloj, BA; Corvalán, AH Review ISI SCOPUS INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Angiogenesis inhibitors in early development for gastric cancer Review ISI SCOPUS EXPERT OPINION ON INVESTIGATIONAL DRUGS (2017)
The twisted survivin connection to angiogenesis Sanhueza, C; Wehinger, S; Bennett, JC; Valenzuela,M.; Owen, GI; Quest, AFG Review ISI SCOPUS Molecular Cancer (2015)
2-Methoxyestradiol and Disorders of Female Reproductive Tissues Pinto, MP; Owen, GI Review ISI SCOPUS HORMONES & CANCER (2014)
Efectos de las estatinas en cáncer: ¿potencial rol en terapéutica y prevención? Cuello F, Mauricio; Kato C, Sumie; Díaz S, Daniela; Owen, Gareth Review SCIELO SCOPUS REVISTA MEDICA DE CHILE (2013)
Effects of statins in cancer Cuello, M.; Kato S.; Diaz, D.; Owen, G Review ISI REVISTA MEDICA DE CHILE (2013)
Glucose Transporters in Sex Steroid Hormone Related Cancer Nualart, F.; Garcia, MDLA; Owen, GI Review ISI CURRENT VASCULAR PHARMACOLOGY (2009)
The action of ovarian hormones in cardiovascular disease Medina, Rodolfo A.; Aranda, Evelyn; VERDUGO, CESAR; Kato, Sumie; Owen, Gareth I. Review ISI SCIELO BIOLOGICAL RESEARCH (2003)
Glucose transporters: expression, regulation and cancer Medina, Rodolfo A.; Owen, Gareth I. Review ISI SCIELO BIOLOGICAL RESEARCH (2002)

Betty San Martin

Directora

Ciencias Clínicas

UNIVERSIDAD DE CHILE, FAC. CIENCIAS VETERINARIAS Y PECUARIAS

Santiago, Chile

Francisca Bronfman

Full Professor

Instituto de Ciencias Biomédicas

Universidad Andrés Bello

Santiago, Chile

Carlos Fardella

Profesor Titular

Endocrinología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Maroun Khoury

Professor

Faculty of Medicine

Universidad de Los Andes

santiago, Chile

Alvaro Lladser

Professor, Principal Investigator

FUNDACIÓN CIENCIA PARA LA VIDA

Santiago, Chile

154

Gareth Owen

Profesor Titular

Fisiologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Jaime Pereira

Jefe

Hematología-Oncología

ESCUELA DE MEDICINA, PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Olga Panes

Technical Director/ Associated Research

Hematology-Oncology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Jorge Carvajal

Chief of Department

Obstetrics

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Eugenia Ortiz

Instructor

Medicina Interna

UNIVERSIDAD DE LA FRONTERA. FACULTAD DE MEDICINA

Temuco, Chile

Andrea Vecchiola

Profesor Asistente

Endocrinologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Mario Chiong

Profesor

Departamento de Bioquímica y Biología Molecular

Universidad de Chile

Santiago, Chile

Paul Vöhringer

Profesor Asociado

Psiquiatría

CLINICA PSIQUIÁTRICA UNIVERSITARIA

Santiago, Chile

Marcelo Kogan

Academico

Quimica Farmacologica y Toxicologica

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

fresia ferreccio

Full Professor, Director PhD Epidemiolgy Program

Public Health

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE FACULTAD DE MEDICINA, ESCUELA DE MEDICINA, DEPARTAMENTO DE SALUD PÚBLICA.

Santiago, Chile

Andrew Quest

Full Professor

Biologia Celular y Molecular

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

RICARDO MORENO

Profesor Titular

Fisiología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, FACULTAD DE CIENCIAS BIOLÓGICAS, DEPTO. DE FISIOLOGÍA

Santiago, Chile

Carmen Romero

Jefe Laboratorio Endocrinología y Biología Reproductiva

Obstetricia y Ginecología

HOSPITAL CLÍNICO UNIVERSIDAD DE CHILE

Santiago, Chile

Marcelo Farias

Assistant Professor

Division of Obstetrics and Gynecology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, DEPARTAMENTO DE OBSTETRICIA

Santiago, Chile

Enrique Castellón

Profesor Titular.

Oncología Básico-Clínica

UNIVERSIDAD DE CHILE

Santiago, Chile

Luis Quinones

PROFESOR TITULAR

ONCOLOGIA BASICO-CLINICA

UNIVERSIDAD DE CHILE

Santiago, Chile

Juan Vera

Full professor

Pathophysiology

University of Concepcion

Concepción, Chile

Alexis Kalergis

Full Professor

Microbiología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE. FACULTAD DE CIENCIAS BIOLÓGICAS

Santiago, Chile

Clemente Palacios

Académico

Química y Farmacia

Universidad Arturo Prat

Iquique, Chile

Juan Opazo

Profesor Titular

Facultad de Medicina y Ciencia

Universidad San Sebastián

Valdivia, Chile

Ricardo Armisen

Associate Professor

Centro de Genética y Genómica

Universidad del Desarrollo

Santiago, Chile

FRANCISCO NUALART

Full Professor and Scientific Director

Cellular Biology and Center for Advanced Microscopy CMA BIO-BIO

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

María García

Profesor Titular

Biología Celular

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

Oslando Padilla

Estadístico

Salud Pública

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Fabiola Sánchez

Associate Profesor

Immunology

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

Luis González

Full Professor

School of Medicine

Universidad San Sebastián

Santiago, Chile

Verónica Palma

Profesor Titular

Biología

UNIVERSIDAD DE CHILE

Santiago, Chile

Denisse Bravo

Profesora Titular

Odontología

Universidad Andrés Bello

Santiago, Chile

Miguel Allende

Director

Biología

FACULTAD DE CIENCIAS, UNIVERSIDAD DE CHILE

Santiago, Chile

Vicente Torres

Associate Professor

Institute for Research in Dental Sciences

FACULTAD DE ODONTOLOGÍA - UNIVERSIDAD DE CHILE

Santiago, Chile

Yolanda Vargas

Profesor Asociado

Producción Vegetal

UNIVERSIDAD DE CONCEPCIÓN

Chillán, Chile

Lisette Leyton

Full Professor

Núcleo Interdisciplinario Biología y Genética

FACULTAD DE MEDICINA UNIVERSIDAD DE CHILE

Santiago, Chile

Javiera Cornejo

PROFESORA ASOCIADA

Medicina Preventiva

FAVET, Universidad de Chile

Santiago, Chile

Maria Vega

Academico Profesora Titular

Obstetricia y Ginecologia Campus Norte

UNIVERSIDAD DE CHILE - FACULTAD DE MEDICINA

Santiago, Chile

Marcelo Garrido

Director

CENTRO DEL CÁNCER, PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Oscar Lazo

Académico

Universidad San Sebastián / University College London

Santiago, Chile

Miguel Concha

Full Professor

Anatomy and Developmental Biology

UNIVERSIDAD DE CHILE

Santiago, Chile

Allisson Astuya

profesor asociado

Departamento de Oceanografia de la Universidad de Concepción

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

Mauricio Cuello

Profesor Titular

Ginecologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE. CENTRO DE INVESTIGACIONES MÉDICAS (CIM)

Santiago, Chile

Sandra Solari

Profesor Clinico Asociado

Laboratorios Clinicos

Facultad de Medicina - PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Arnoldo Riquelme

Profesor titular

Gastroenterología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, DEPARTAMENTO DE GASTROENTEROLOGÍA

Santiago, Chile

Cesar Sanchez

Profesor asistente

Hematologia-oncologia

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

santiago, Chile

Andres Carvajal

Investigador

INIA

Osorno, Chile

Franz Villarroel

Jefe Laboratorio - PI

Departamento de Investigación del Cáncer

Fundación Arturo López Pérez

Santiago, Chile

Maria Opazo

Profesor Asociado

Universidad de Las Américas

Santiago, Chile

Soledad Henriquez

Profesor Asistente

INSTITUTO DE INVESTIGACIONES MATERNO INFANTIL, FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

German Reig

Investigador Principal

Centro integrativo de Biología y Química Aplicada

Universidad Bernardo O'Higgins

Santiago, Chile

Fernando Gonzalez

Titular Professor

Facultad de Ciencias de la Vida

Universidad Andres Bello

Santiago, Chile

Ricardo Ramires

Director Científico

Centro de Oncología de Precisión

Universidad Mayor de Chile

Santiago, Chile

Alejandro Godoy

Associate Professor

Centro de Biología Celular y Biomedicina

Universidad San Sebastián

Santiago, Chile

PAMELA LEAL

Profesor Asociado

Departamento de Ciencias Agronómicas y Recursos Naturales

UNIVERSIDAD DE LA FRONTERA

Temuco, Chile

Mariana Cifuentes

Professor

Instituto de Nutricion y Tecnologia de los Alimentos

INTA UNIVERSIDAD DE CHILE

Santiago, Chile

Flavio Salazar

Profesor Titular

Oncología Básico Clínica

Universidad de Chile

SANTIAGO, Chile

Alejandro Martinez

Profesor Asociado

Pediatría

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago de Chile, Chile

Cristian Carvajal

Associate Professor

Endocrinologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Rene Baudrand

Profesor Asociado

Endocrinología

Pontificia Universidad Católica de Chile

Santiago, Chile

Daniel Aguayo

Associate Professor

ITISB

UNIVERSIDAD ANDRES BELLO

Viña del Mar, Chile

Juan Roa

Chair

Pathology

Pontificia Universidad Catolica de Chile

santiago, Chile

ALEJANDRO CORVALAN

Principal Investigator

Hematology and Oncology

Pontificia Universidad Catolica de Chile

Santiago, Chile

Bruno Nervi

Associated Professor

Hematology - Oncology

Pontificia Universidad Catolica de Chile

Santiago, Chile

Ignacio Espinoza

Profesor Asociado

Pontificia Universidad Católica de Chile

Santiago, Chile

Julio Benites

Profesor Titular

Química y Farmacia

Universidad Arturo Prat

Iquique, Chile

Alberto Martin

Associate professor

Centro Ciencia & Vida

Universidad San Sebastián

Santiago, Chile

Julio Amigo

Assistant Professor

Physiology

Pontificia Universidad Catolica de Chile

Santiago, Chile

Tomas Perez-Acle

Full Professor

Computational Biology Lab

Fundación Ciencia para la Vida

Santiago, Chile

Claudia Saez

Associate Professor

Hematology-Oncology

Pontificia Universidad Católica de Chile

Santiago, Chile

Carlos Lagos

Profesor Asociado

FACULTAD DE MEDICINA Y CIENCIA

UNIVERSIDAD SAN SEBASTIÁN

SANTIAGO, Chile

Claudia Riedel

Full Professor

Life Sciences

Universidad Andres Bello

Santiago, Chile

Mercedes López

Profesora Asociada

Instituto de Ciencias Biomédicas

Universidad de chile

Santiago, Chile

JULIO TAPIA

Full Professor

Program of Cellular and Molecular Biology

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

Alfredo Criollo

Associated Professor

Research Institute in Dental Sciences

Facultad de Odontología, Universidad de Chile

Santiago, Chile

LUIS SOBREVIA

Professor

Division of Obstetrics and Gynaecology

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

Luis Velasquez

Director and Full Professor

Medicine

Universidad SEK

Santiago, Chile

RENAN FELIPE ORELLANA WALDEN

Francisco Aguayo

Profesor Titular

Departamento de Ciencias Biomédicas

Universidad de Tarapacá

Arica, Chile

MARIA DURAN

Estudiante

Universidad Mcgill

Montreal, Canada

MANUEL VARAS

Research Professor

UNIVERSIDAD SAN SEBASTIÁN

Santiago, Chile

Manuel Espinoza

Profesor Asociado

Salud Pública

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

Sergio Wehinger

Académico Asociado

Bioquímica Clínica e Inmunohematología

UNIVERSIDAD DE TALCA

Talca, Chile

Adrian Paredes

Academico

Química

UNIVERSIDAD DE ANTOFAGASTA

Antofagasta, Chile

Ismael Riquelme

Académico - Investigador

Ciencias de la Salud

UNIVERSIDAD AUTÓNOMA DE CHILE

Temuco, Chile

Carmen Lemus

Post Doc

Laboratorio de Estudios Ontogénicos - Universidad de CHile

Santiago, Chile

Mauricio Pinto

Investigador

STORM SPA

Santiago, Chile

Maria Otero

Profesor Asociado

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

Eugenia Morselli

Profesor Asociado de Planta Ordinaria

Fisiología

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago de Chile, Chile

Carlos Lafourcade

Profesor Asociado

UNIVERSIDAD DE LOS ANDES

Chile

Manuel Valenzuela

Académico Investigador

VRA

Universidad Central de Chile

santiago, Chile

Carolina Bizama

Assistant professor

Department of Pathology

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

Pedro Buc

Profesor titular

Quimica y Farmacia

Universidad Arturo Prat

Iquique, Chile

María Rodríguez

Profesora Asociada

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

Patricio Silva

Investigador Principal FONDEF

Departamento de Biología Celular y Molecular

Universidad de Chile

Santiago, Chile

Alejandra Sandoval

Associate Professor

Faculty of Sciences

Pontificia Universidad Católica de Valparaíso

Valparaiso, Chile

Paola Casanello

Profesor Asociado

División de Obstetricia y Ginecología

Pontificia Universidad Católica de Chile

Santiago, Chile

Lorena Mosso

profesor titular

endocrinologia

Pontificia Universidad Catolica de Chile

santiago, Chile

Gabriel Bastias

Profesor Asociado

Facultad de Medicina

Pontificia Universidad Católica de Chile

Santiago, Chile

Pia Villarroel

Académico

Facultad de Ciencias para el Cuidado de la Salud

Universidad San Sebastián

Valdivia, Chile

Lorena Lobos

Principal Investigator-Associate Proffesor

Facultad of Medicine - Clinic Alemana

Universidad Del Desarrollo

santiago, Chile

Jaime Cerda

Profesor Asociado

Salud Pública

Pontificia Universidad Católica de Chile

Santiago, Chile

Rafaela Erices

Postdoctorante

Ginecología y Obstetricia

Pontificia Universidad Católica de Chile

Santiago, Chile

Pablo Lois

Asistente de Investigación

Biología

Universidad de Chile

Santiago, Chile

Cristian Vilos

Full Professor

Departamento de Ciencias Preclínicas

Universidad de Talca

Talca, Chile

Francisco Morales

Posdoctoral

Universidad de Chile. Centro FONDAP ACCDiS

Santiago, Chile

Paula Sotomayor

Investigador

Medicina

Pontificia Universidad Católica de Chile

Santiago, Chile

Ignacio Retamal

Assistant Professor

Centro de Oncología de Precisión

Universidad Mayor de Chile

Santiago, Chile

katherine Stack

Maria Gago

Profesor Asistente

Facultad de Física

Pontificia Universidad Católica de Chile

Santiago, Chile

Fidel Allende

Quimico

Laboratorios Clinicos

Pontificia Universidad Católica de Chile

Santiago, Chile

Claudia Quezada

Full Professor

Institute of Biochemistry and Microbiology

Universidad Austral de Chile

Valdivia, Chile

jose dominguez

Profesor Asistente

Endocrinologia

Pontificia Universidad Catolica de Chile

Santiago, Chile

mauricio cuello

Mariana Rios

Investigador

Facultad de Ciencias Biológicas

pontificia Universidad Católica de Chile

Santiago, Chile

Hernán Huerta

Asistente de Investigación

Centro de Biología Integrativa

Universidad Mayor de Chile

Santiago, Chile

Juan Lecaros

Associate professor

Institute of Science and Innovation in Medicine

Universidad del Desarrollo

Santiago, Chile

Eduardo Fuentes

Profesor Asistente

Ciencias de la Salud

Universidad Católica de Chile

Santiago, Chile

Helga Weber

Investigador

Vicerrectoría de Investigación y Post Grado

Universidad de la Frontera

Temuco, Chile

José Rocha

Postdoctoral Researcher

Facultad de Veterinaria

Universidad San Sebastián

Puerto Montt, Chile

Tomas de Mayo

PROFESOR ASOCIADO

CIENCIAS

UNIVERSIDAD MAYOR

SANTIAGO, Chile

Paula Solar

Directora de Investigación y Doctorados

Dirección de Investigación y Doctorados

Universidad Finis Terrae

Santiago, Chile

Patricia Fuenzalida

Lab Manager

Fisiología

Pontificia Universidad Católica de Chile

Santiago, Chile

Lorena Abarzúa

Investigador

Medicina

Universidad de los Andes

Santiago, Chile

Fabian Tempio

Asistente de Investigación

Instituto de Ciencias Biomédicas

Universidad de Chile

Santiago, Chile

Ethel Velásquez

Directora (t) Centro de Investigaciones Nucleares para Aplicaciones en Salud y Biomedicina

Comisión Chilena de Energía Nuclear

Santiago, Chile

Cristina Bertocchi

Assistant Professor

Department of Physiology

Pontificia Universidad Católica de Chile

Santiago, Chile

Benjamin Garcia

Director

Facultad de Estudios Interdisciplinarios

Universidad Mayor de Chile

Santiago, Chile

EVA BUSTAMANTE

JEFE DE COORDINACION CIENTIFICA

INVESTIGACION Y DOCENCIA

FUNDACION ARTURO LOPEZ PEREZ

Santiago, Chile

María Maturana

Bioquimico

Pontificia Universidad Católica de Chile

Santiago, Chile

Javiera Sateler

Profesor Auxiliar

Ciencias Clínicas

Universidad Católica del Maule

Talca, Chile

Francisco Acevedo

Medico Oncologo

Hemato Oncologia

Pontificia Universidad Católica de Chile

Santiago, Chile

Pedro Torres

Ayudante laboratorio

Universidad de Chile

Santiago, Chile

ALEJANDRA TAPIA

Investigador

Endocrinología

Pontificia Universidad Católica de Chile

Santiago, Chile

Charlotte Hill

Postdoctoral Fellow

CIIB

Universidad de Los Andes

Santiago, Chile

Miguel Cordova

Estudiando de Doctorado

Departamento de Posgrado

Universidad de Chile

Santiago, Chile

Ana Meneses

Académico

Universidad Diego Portales

Santiago, Chile

Javier Pizarro

Assitant Professor

Obstetrics and Gynecology

Pontificia Universidad Católica de Chile

Santiago, Chile

Trinidad Montero

postdoctorate

Medicine

Pontificia Universidad Católica de Chile

Santiago, Chile

Claudia Pissani

Erica Koch

Oncólogo Médico

Red de Salud UC Christus

Santiago, Chile

María Villarroel

Médico Anátomo-Patólogo

Anatomía Patológica

Red de Salud UC Christus / Pontificia Universidad Católica de Chile

Santiago, Chile

FERNANDO CROVARI

Jefe Departamento

Cirugía Digestiva

Pontificia Universidad Católica de Chile

Santiago, Chile

RENAN ORELLANA

Investigador

Ciencias Químicas y Biológicas

Universidad Bernardo O'Higgins

Santiago, Chile

Natalia Landeros

Profesor Asistente

Ciencias Preclínicas

Universidad Católica del Maule

Talca, Chile

PABLO PEREZ

Profesor investigador

Programa de Comunicación en Cáncer

Universidad del Desarrollo

Santiago, Chile

Ignacio Wichmann

Assitant Professor

Obstetrics

Pontificia Universidad Católica de Chile

Santiago, Chile

Diego Carrillo

Profesor auxiliar

Instituto de Bioquímica y Microbiología

Universidad Austral de Chile

Valdivia, Chile

Maria Hernandez

Investigador Post Doctoral

Universidad de Chile

Santiago, Chile

Karen Oróstica

Vigilancia genómica

Genética Molecular

Universidad de Tal

Santiago, Chile

German Osorio

Especialista en Microscopia

Biologia Celular

Universidad de Concepción

Concepción, Chile

Sebastian Morales

Académico e Investigador

Facultad de Medicina y Ciencias de la Salud

Universidad Mayor de Chile

Santiago, Chile

Roddy Jorquera

Investigador

Investigación del cáncer

Fundación Arturo López Pérez

Santiago, Chile

Javiera Obreque

Investigadora Postdoctoral

CECAN - PUC

Santiago, Chile

Matías Muñoz

Research Assistant

Universidad Mayor de Chile

Santiago, Chile

Anil Sadarangani

Director de Innovacion

Innovacion

Universidad de Los Andes

santiago, Chile

Hegaly Mendoza

Académico

Universidad Andrés Bello

Santiago, Chile

Isabel Lizama

Ivania Valdes

Estudiante de Doctorado

Vicerrectoria de investigación

Universidad Mayor de Chile

Santiago, Chile

Gareth Ivor Owen Jardine

Líneas de Investigación

Educación

Biotecnologia, KINGS COLLEGE LONDON. Reino Unido, 1992

Bioquimica, UNIVERSITY OF LONDON. Chile, 1996

Experiencia Académica

Profesor Asistente / Asociado Full Time

Profesor Titular Full Time

Profesor Titular Full Time

Experiencia Profesional

Post doctorado Full Time

Postdoctorado Full Time

Medical Directior Part Time

Board Member Part Time

Board Member Part Time

Formación de Capital Humano

Difusión y Transferencia

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