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Lorena Alejandra Abarzúa Catalán

Investigador

Universidad de los Andes

Santiago, Chile

Fetal-Maternal Medicine, prenatal stress, Chronobiology, extracellular vesicles, Neurobiology, Molecular Biology

Sciences (Molecular and Cellular Biology), UNIVERSIDAD AUSTRAL DE CHILE. Chile, 2012
Biochemistry, UNIVERSIDAD AUSTRAL DE CHILE. Chile, 2007
Biochemistry, UNIVERSIDAD AUSTRAL DE CHILE. Chile, 2007

Profesor curso PEC Other

UNIVERSIDAD DE CHILE

Medicina

Santiago, Chile

2013 - 2013
Profesor curso PEC Other

UNIVERSIDAD DE CHILE

Medicina

Santiago, Chile

2014 - 2014
Profesor curso PEC Other

UNIVERSIDAD DE CHILE

Medicina

Santiago, Chile

2015 - 2015
Constructor Prueba INICIA de Biologia Other

UNIVERSIDAD DE CHILE

CIAE

Santiago, Chile

2013 - 2014
TUTOR Programa de Inmersión en Investigación Full Time

Universidad de los Andes

Medicina

Santiago, Chile

2018 - A la fecha

Postdoc Full Time

Universidad de los Andes

Santiago, Chile

2017 - A la fecha
Postdoc Full Time

Pontificia Universidad Católica de Chile

Chile

2013 - 2016
Postdoc Full Time

Pontificia Universidad Católica de Chile

Chile

2012 - 2017
Estudiante de práctica Full Time

GRUPO BIOS

Santiago, Chile

2006 - 2007
Asistente de investigación Full Time

Universidad Austral de Chile

Valdivia, Chile

2007 - 2008
Asistente de investigación Full Time

Universidad de Chile

Santiago, Chile

2008 - 2009

TUTORIAS
• Isidora Solar Costabal: Seminario de Investigación BIOQ-296C. Título de tesis: “Leptina promueve un microambiente proinflamatorio que favorece la carcinogénesis en células de cáncer de ovario”. Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile.

• Natalia Salazar y Jacinta Sigala. Programa de Inmersión en Investigación, Escuela de Medicina, Facultad de Medicina, Universidad de los Andes.

• Ana del Valle Lezcano. Práctica profesional (diciembre 2019-febrero 2020). Escuela de Biotecnología, Universidad Mayor.

BECA DOCTORADO NACIONAL

CONSEJO NACIONAL DE CIENCIA Y TECNOLOGIA

Chile, 2008

Beca para estudios de doctorado en Chile.
Fondecyt Postdoctorado

CONSEJO NACIONAL DE CIENCIA Y TECNOLOGIA

Chile, 2013

Adjudicación concurso Fondecyt Postdoctorado año 2013, Proyecto N°3140335
Apoyo tesis doctoral

CONSEJO NACIONAL DE CIENCIA Y TECNOLOGIA

Chile, 2010

Beca de apoyo para realización de la tesis doctoral.
Término de tesis doctoral

CONSEJO NACIONAL DE CIENCIA Y TECNOLOGIA

Chile, 2012

Beca para finalización de tesis de doctorado.
AMSUD Pasteur

Instituto Pasteur

Francia, 2012

Beca para pasantía en el Instituto Pasteur de París
Wellcome Trust Travel Award

Wellcome Trust

Reino Unido, 2011

Beca para asistencia al congreso de la European Biological Rhythms Society


Astrocyte-Derived Small Extracellular Vesicles Regulate Dendritic Complexity through miR-26a-5p Activity Alejandro Luarte; Roberto Henzi; Anllely Fernández; Diego Gaete; Pablo Cisternas; matias pizarro ; Luis Federico Batiz; Isabel Villalobos; Matias Masalleras; Rodrigo Vergara; Manuel Varas-Godoy,; Lorena Abarzua-Catalan; Rodrigo Herrera-Molina; Carlos Lafourcade; Ursula Wyneken Article CELLS (2020)
Chronic Fluoxetine Treatment Induces Maturation-Compatible Changes in the Dendritic Arbor and in Synaptic Responses in the Auditory Cortex Ampuero, Estibaliz; Cerda, Mauricio; hartel, Steffen; Javier Rubio, Francisco; Massa, Solange; Cubillos, Paula; Abarza-Cataln, Lorena; Sandoval, Rodrigo; Galaburda, Albert M.; Wyneken, Ursula Article ISI SCOPUS FRONTIERS IN PHARMACOLOGY (2019)
Developmental Programming of Capuchin Monkey Adrenal Dysfunction by Gestational Chronodisruption Richter, HG; Mendez, N; Abarzua-Catalan, L; Valenzuela GJ; Seron-Ferre, M; Torres-Farfan, C Article ISI SCOPUS BIOMED RESEARCH INTERNATIONAL (2018)
LEPTIN PROMOTES A MORE AGGRESIVE BEHAVIOR OF OVARIAN CANCER CELLS: A POTENTIAL EXPLANATION FOR A WORSE PROGNOSIS IN OBESE OVARIAN CANCER PATIENTS Cuello-Fredes, M.; Kato, S.; Abarzua-Catalan, L.; Delpiano, A.; Trigo, C.; Garcia, K.; Sanhueza, C.; Ibanez, C.; Branes, J.; Castellon, E.; Owen, G. Article ISI INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER (2015)
Leptin stimulates migration and invasion and maintains cancer stem-like properties in ovarian cancer cells: an explanation for poor outcomes in obese women Kato, Sumie; Abarzua-Catalan, Lorena; Trigo, Cesar; Delpiano, Ana; Sanhueza, Cristobal; Garcia, Karen; Ibanez, Carolina; Hormazabal, Katherine; Diaz, Daniela; Branes, Jorge; Castellon, Enrique; Bravo, Erasmo; Owen , Gareth; Cuello, Mauricio Article ISI ONCOTARGET (2015)
Gestational Chronodisruption Impairs Hippocampal Expression of NMDA Receptor Subunits Grin1b/Grin3a and Spatial Memory in the Adult Offspring Vilches, N; Spichiger, C.; Mendez, N.; Abarzua-Catalan, L; Galdames, HA; Hazlerigg, DG; Richter, HG; Torres-Farfan, C Article ISI SCOPUS PLOS ONE (2014)
Impact of gestational chronodisruption on fetal cardiac genomics Galdames H.A.; Torres-Farfan, C; Spichiger, C.; Mendez, N.; Abarzua-Catalan, L; Alonso-Vazquez, P; Richter, H. G. Article ISI SCOPUS JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2014)
Circadian rhythms in the fetus Maria Seron-Ferre, Natalia Mendez; Lorena Abarzua-Catalan, Nelson Vilches; Francisco Valenzuela, Henry Reynolds; Anibal LLanos, Auristela Rojas; Guillermo Valenzuela, Claudia Torres-Farfan Article Molecular and Cellular Endocrinology (2012)
Timed Maternal Melatonin Treatment Reverses Circadian Disruption of the Fetal Adrenal Clock Imposed by Exposure to Constant Light Mendez, N.; Abarzua-Catalan, L; Vilches, N; Galdames H.A.; Spichiger, C.; Richter, H. G.; Valenzuela G.J.; Seron-Ferre, M; Torres-Farfan, C Article ISI SCOPUS PLOS ONE (2012)
Timed Maternal Melatonin Treatment Reverses Circadian Disruption of the Fetal Adrenal Clock Imposed by Exposure to Constant Light Natalia Mendez, Lorena Abarzua-Catalan; Nelson Viches, Hugo Galdames; Carlos Spichiger, Hans Richter; Guillermo Valenzuela, Maria Seron-Ferre Article Plos One (2012)
A Circadian Clock Entrained by Melatonin Is Ticking in the Rat Fetal Adrenal Torres-Farfan, C; Mendez, N.; Abarzua-Catalan, L; Vilches, N; Valenzuela GJ; Seron-Ferre, M Article ISI SCOPUS Endocrinology (2011)
A circadian clock entrained by melatonin is ticking in the rat fetal adrenal. Claudia Torres-Farfan, Natalia Mendez; Lorena Abarzua-Catalan, Nelson Vilches; Guillermo Valenzuela, Maria Seron-Ferre Article Endocrinology (2011)
Melatonin Exerts Direct Inhibitory Actions on ACTH Responses in the Human Adrenal Gland Campino C.; Valenzuela, FJ; Torres-Farfan, C; Reynolds, HE; Abarzua-Catalan, L; Arteaga, E; Trucco, C; Guzman, S; Valenzuela GJ; Seron-Ferre, M Article ISI SCOPUS Hormone and Metabolic Research (2011)
Melatonin exerts direct inhibitory actions on ACTH responses in the human adrenal gland. Carmen Campino, Francisco Valenzuela; Claudia Torres-Farfan, Henry Reynolds; Lorena Abarzua-Catalan, E. Arteaga; C. Trucco, S. Guzmán; Guillermo Valenzuela, Maria Seron-Ferre Article Hormone and Metabolic Research (2011)
Cryptochrome 2 Expression Level Is Critical for Adrenocorticotropin Stimulation of Cortisol Production in the Capuchin Monkey Adrenal Torres-Farfan, C; Abarzua-Catalan, L; Valenzuela, FJ; Mendez, N.; Richter, HG; Valenzuela GJ; Seron-Ferre, M Article ISI SCOPUS ENDOCRINOLOGY (2009)
Cryptochrome 2 expression level is critical for adrenocorticotropin stimulation of cortisol production in the capuchin monkey adrenal. Claudia Torres-Farfan, Lorena Abarzua-Catalan; Francisco Valenzuela, Natalia Mendez; Hans Richter, Guillermo Valenzuela Article Endocrinology (2009)
Rhythmic expression of functional MT1 melatonin receptors in the rat adrenal gland Richter, HG; Torres-Farfan, C; Garcia-Sesnich, J; Abarzua-Catalan, L; Henriquez, MG; Alvarez-Felmer, M; Gaete, F; Rehren, GE; Seron-Ferre, M Article ISI SCOPUS ENDOCRINOLOGY (2008)
Rhythmic expression of functional MT1 melatonin receptors in the rat adrenal gland. Hans Richter, Claudia Torres-Farfan; Jocelyn Garcia-Sesnich, Lorena Abarzua-Catalan; Mauricio Henriquez, Mauro Alvarez-Felmer; German Rehren, Maria Seron-Ferre Article Endocrinology (2008)


Simvastatin modifies the expression of stemness and epithelial-mesenchymal transition (EMT) markers in ovarian cancer-initiating cells resulting in decreased cell migration Kato, S; Abarzua, L.; Hormazábal K.; Delpiano, A.; Bravo, ML; Orellana, R; Brañes J.; Castellón E.; Cuello-Fredes, M; Owen, GI Abstract ISI EUROPEAN JOURNAL OF CANCER (2014)
2-Methoxyestradiol induces differentiation of epithelial ovarian cancer-initiating cells sensitizing them to chemotherapy. Cuello, MA; Kato, S; Hormazábal K.; Abarzua, L.; Bravo, L; Barriga, I; Barrena, N; Brañes J.; Bravo, E.; Gejman, R; Castellón E.; Owen, G Abstract ISI CANCER RESEARCH (2013)


Molecular mechanism behind the Beneficial Effects of Statins in Ovarian Cancer Mauricio A. Cuello; Sumie Kato; Lorena Abarzúa-Catalán; Eric R. Travers BookSection (2015)


Circadian rhythms in the fetus Seron-Ferre, M; Mendez, N.; Abarzua-Catalan, L; Vilches, N; Valenzuela F. J.; Reynolds H.E.; Llanos, A. J.; Rojas A.; Valenzuela G.J.; Torres-Farfan, C Review ISI SCOPUS Molecular and Cellular Endocrinology (2012)