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Francisco Javier Valenzuela Melgarejo

Academico

UNIVERSIDAD DEL BÍO BÍO

Chillan, Chile

Fisiologia; Endocrinología; Sistema Circadiano; Biología Celular y Molecular

Ciencias Biomédicas, UNIVERSIDAD DE CHILE. Chile, 2012
Bioquímico, UNIVERSIDAD DE CHILE. Chile, 2005

Academico Full Time

UNIVERSIDAD DEL BIO-BIO

Ciencias

Chillán, Chile

2012 - A la fecha

Asistente Investigación Fondecyt (1110883) Full Time

Universidad de los Andes

Santiago, Chile

2011 - 2012
Director Alterno Proyecto CORFO (11IDL2-10487) Other

Universidad de los Andes

Santiago, Chile

2011 - 2012

He dirigido 3 tesis de Pregrado: “MELATONINA Y SU ROL SOBRE EL SISTEMA CIRCADIANO DE LA PLACENTA HUMANA”, Ped. Ciencias, 2014, Marcela Pradenas ; “HIGH LEVEL OF CLOCK GENE PER1 IS DETECTED IN PLACENTAS FROM PREECLAMPSIA”. Ped. Ciencias, 2014, Karen Muñoz, Sara Muñoz, Solange Oyarce; “PAPEL DEL SISTEMA CIRCADIANO Y DE MELATONINA EN LAS PATOLOGÍAS DEL EMBARAZO” Bachillerato, 2013. Fabiola Pino.

He dirigido 1 tesis de Postgrado: “EL SISTEMA CIRCADIANO MODULA EL CICLO CELULAR DE LA PLACENTA: MECANISMO MOLECULAR DEL CONTROL CELULAR”, Magister en Cs. Biológicas, 2015. Carlos Venegas.


Effect of metal in Schiff bases of chitosan adsorbed on glassy carbon electrode in the inhibition of sphingomyelinase C toxin Caro-Diaz, Claudia A.; Lillo-Arroyo, Luis; Valenzuela-Melgarejo, Francisco J.; Roudergue-Zuniga, Victor; Cabello-Guzman, Gerardo Article ISI SCOPUS FOOD AND CHEMICAL TOXICOLOGY (2018)
Carriage of Staphylococcus aureus among food service workers Alarcón-Lavín, MP; Valenzuela, FJ Article ISI REVISTA MEDICA DE CHILE (2017)
Mechanistic characterization and inhibition of sphingomyelinase C over substituted Iron Schiff bases of chitosan adsorbed on glassy carbon electrode Article ISI SCOPUS CHEMICO-BIOLOGICAL INTERACTIONS (2017)
Evidences of Polymorphism Associated with Circadian System and Risk of Pathologies: A Review of the Literature Article ISI SCOPUS INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (2016)
Oxidation of melatonin on a glassy carbon electrode modified with metallic glucosamines. Synthesis and characterization Caro C.A.; Lillo, L; Valenzuela F. J.; Cabello, G; Lang, E.; Vallejos, D; Castillo, C Article ISI SCOPUS JOURNAL OF SOLID STATE ELECTROCHEMISTRY (2016)
Circadian System and Melatonin Hormone: Risk Factors for Complications during Pregnancy Article Obstetrics and Gynecology International (2015)
Impact of maternal melatonin suppression on amount and functionality of brown adipose tissue (BAT) in the newborn sheep Reynolds H.; Mendez, N; Mondaca, M.; Valenzuela F. J.; R E.; Herrera, E. A.; Llanos, A. J. Article SCOPUS FRONTIERS IN ENDOCRINOLOGY (2014)
Increased placental angiogenesis in late and early onset pre-eclampsia is associated with differential activation of vascular endothelial growth factor receptor 2 Escudero C, Celis C, Saez T, San Martin S, Valenzuela FJ, Aguayo C, Bertoglia P, Roberts JM, Acurio J Article ISI PLACENTA (2014)
Impact of Chronodisruption during Primate Pregnancy on the Maternal and Newborn Temperature Rhythms Seron-Ferre, M; Forcelledo, ML; Torres-Farfan, C; Valenzuela, FJ; Rojas, A; Vergara, M; Rojas-Garcia, PP; Valenzuela GJ Article ISI SCOPUS PLOS ONE (2013)
Low 2-methoxyestradiol levels at the first trimester of pregnancy are associated with the development of pre-eclampsia Perez-Sepulveda, A; Torres, M. J.; Valenzuela F. J.; Larrain, R; Figueroa-Diesel, H; Galaz, J; Nien, J. K.; Serra, R; Michea, L; Illanes, S. E. Article ISI SCOPUS Prenatal Diagnosis (2012)
Pathogenesis of preeclampsia: The genetic component Valenzuela F. J.; Perez-Sepulveda, A; Torres, M. J.; Correa, P; Repetto, G. M.; Illanes, S. E. Article SCOPUS Journal of Pregnancy (2012)
Melatonin Exerts Direct Inhibitory Actions on ACTH Responses in the Human Adrenal Gland Campino C.; Valenzuela, FJ; Torres-Farfan, C; Reynolds, HE; Abarzua-Catalan, L; Arteaga, E; Trucco, C; Guzman, S; Valenzuela GJ; Seron-Ferre, M Article ISI SCOPUS Hormone and Metabolic Research (2011)
Cryptochrome 2 Expression Level Is Critical for Adrenocorticotropin Stimulation of Cortisol Production in the Capuchin Monkey Adrenal Torres-Farfan, C; Abarzua-Catalan, L; Valenzuela, FJ; Mendez, N; Richter, HG; Valenzuela GJ; Seron-Ferre, M Article ISI SCOPUS ENDOCRINOLOGY (2009)
Circadian cortisol secretion and circadian adrenal responses to ACTH are maintained in dexamethasone suppressed capuchin monkeys (Cebus apella) Torres-Farfan, C; Valenzuela, FJ; Ebensperger, R; Mendez, N; Campino C.; Richter, HG; Valenzuela GJ; Seron-Ferre, M Article ISI SCOPUS AMERICAN JOURNAL OF PRIMATOLOGY (2008)
Clock gene expression in adult primate suprachiasmatic nuclei and adrenal: Is the adrenal a peripheral clock responsive to melatonin? Valenzuela, FJ; Torres-Farfan, C; Richter, HG; Mendez, N; Campino C.; Torrealba, F.; Valenzuela GJ; Seron-Ferre, M Article ISI SCOPUS ENDOCRINOLOGY (2008)
Evidence of a role for melatonin in fetal sheep physiology: direct actions of melatonin on fetal cerebral artery, brown adipose tissue and adrenal gland Torres-Farfan, C; Valenzuela, FJ; Mondaca, M.; Valenzuela GJ; Krause, B; Herrera, EA; Riquelme, R; Llanos, AJ; Seron-Ferre, M Article ISI SCOPUS JOURNAL OF PHYSIOLOGY-LONDON (2008)
La melatonina reduce la respuesta de cortisol al ACTH en humanos Campino, Carmen; Valenzuela, Francisco; Arteaga, Eugenio; Torres-Farfán, Claudia; Trucco, Cristian; Velasco, Alfredo; Guzmán, Sergio; Serón-Ferré, María Article SCIELO REVISTA MEDICA DE CHILE (2008)
Melatonin reduces cortisol response to ACTH in humans Campino C.; Valenzuela, F; Arteaga, E; Torres-Farfan, C; Trucco, C; Velasco, A; Guzman, S; Seron-Ferre, M Article ISI REVISTA MEDICA DE CHILE (2008)
Melatonin reduces cortisol response to ACTH in humans La melatonina reduce la respuesta de cortisol al ACTH en humanos Campino C.; Arteaga, E; Valenzuela, F; Torres-Farfan, C; Seron-Ferre, M; Trucco, C; Velasco, A; Guzman, S Article SCOPUS REVISTA MEDICA DE CHILE (2008)
Maternal melatonin effects on clock gene expression in a nonhuman primate fetus Torres-Farfan, C; Rocco, V; Monso, C; Valenzuela, FJ; Campino C.; Germain, A; Torrealba, F.; Valenzuela GJ; Seron-Ferre, M Article ISI SCOPUS ENDOCRINOLOGY (2006)
Maternal melatonin stimulates growth and prevents maturation of the capuchin monkey fetal adrenal gland Torres-Farfan, C; Valenzuela, FJ; Germain, AM; Viale, ML; Campino C.; Torrealba, F.; Valenzuela GJ; Richter, HG; Seron-Ferre, M Article ISI SCOPUS JOURNAL OF PINEAL RESEARCH (2006)


The RNA Levels of Keys Enzimes for the Methionine-Homocysteine Metabolism Are Elevated in Placenta of Preeclamptic (PE) Patients Valenzuela, FJ; Perez-Sepulveda, A; Torres, MJ; Galaz, J; Guzmán, A; Mena, F; Figueroa-Diesel, H; Illanes, S Abstract ISI REPRODUCTIVE SCIENCES (2012)
A Different Temporal Order between Fetal Atrium and Ventricle? Identification of Adrenergic Receptor Beta 1 (ADRB1), Atrial Natriuretic Peptide (ANP), Clock Genes and Melatonin Receptor 1 (MT1) in Fetal Capuchin Monkey Heart. Preliminary Results Rocco, V; Valenzuela, FJ; Torres-Farfan, C; Reynolds H.; Mendez, N; Abarzua-Catalan, L; Rojas, A; Valenzuela GJ; Seron-Ferre, M Abstract ISI REPRODUCTIVE SCIENCES (2010)
Interactions between Melatonin and ACTH in the Human Adrenal Gland: Adrenal Clockwork Inhibition?. Campino C.; Valenzuela, FJ; Torres-Farfan, C; Abarzua-Catalan, L; Reynolds, HE; Arteaga, E; Trucco, C; Guzman, S; Valenzuela GJ; Seron-Ferre, M Abstract ISI ENDOCRINE REVIEWS (2010)
Different effects of melatonin on PER2 expression in the adrenal gland of fetal and adult Capuchin monkey Valenzuela, F; Monso, C; Torres-Farfan, C; Campino C.; Torrealba, F.; Germain, A; Seron-Ferre, M Abstract ISI PLACENTA (2006)
Differential expression of the clock gene Cry2 in capuchin monkey fetal tissues Rocco, V; Torres-Farfan, C; Valenzuela, F; Torrealba, F.; Germain, A; Campino, B; Seron-Ferre, M Abstract ISI PLACENTA (2006)
Maternal melatonin inhibits 30-hydroxysteroid-dehydrogenase expression in the primate fetal adrenal gland. Torres-Farfan, C; Valenzuela, FJ; Viale, ML; Germain, A; Valenzuela GJ; Campino C.; Torrealba, F.; Richter, HG; Seron-Ferre, M Abstract ISI JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION (2004)
Regulation of 3b-hydroxysteroid dehydrogenase (3b-HSD) expression in the capuchin monkey fetal adrenal gland by maternal melatonin. Torres-Farfan, C; Valenzuela, FJ; Germain, AM; Campino C.; Valenzuela GJ; Richter, HG; Torrealba, F.; Seron-Ferre, M Abstract ISI PEDIATRIC RESEARCH (2004)


The role of placenta in the fetal programming associated to gestational diabetes Carlos Escudero, Francisco Valenzuela, Jesenia Acurio, Luis Sobrevia, Marcelo González; Luis Sobrevia BookSection (2013)


Potential Crosstalk between Fructose and Melatonin: A New Role of Melatonin-Inhibiting the Metabolic Effects of Fructose Valenzuela-Melgarejo, FJ Review ISI SCOPUS INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (2018)
Circadian rhythms in the fetus Seron-Ferre, M; Mendez, N; Abarzua-Catalan, L; Vilches, N.; Valenzuela F. J.; Llanos, A. J.; Rojas, A; Torres-Farfan, C Review ISI SCOPUS Molecular and Cellular Endocrinology (2012)