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Rodrigo Andrés Sandoval Guzmán

Director de departamento

UNIVERSIDAD CATOLICA DEL NORTE

Coquimbo, Chile

Líneas de Investigación


Disfunción sináptica en enfermedades neurodegenerativas efecto de productos naturales sobre enfermedades del SNC bases moleculares del autismo

Educación

  •  Ciencias m/Biología Celular, Molecular y Neurociencias, UNIVERSIDAD DE CHILE. Chile, 2008
  •  Bioquímico, UNIVERSIDAD DE CHILE. Chile, 2002

Experiencia Académica

  •   Director de Departamento Full Time

    UNIVERSIDAD CATOLICA DEL NORTE

    Medicina

    Coquimbo, Chile

    2015 - A la fecha

  •   profesor hora Other

    CASA DE ESTUDIO PEDRO DE VALDIVIA LTDA.

    Ciencias Agropecuarias

    La Serena, Chile

    2019 - A la fecha

  •   Profesor Asociado Full Time

    Universidad Catolica del Norte

    Medicina

    Coquimbo, Chile

    2009 - A la fecha

Formación de Capital Humano


Dirección de 7 tesis de pre-grado
Co-Dirección de 1 tesis de pregrado



 

Article (18)

Characterization of the antagonist actions of 5-BDBD at the rat P2X4 receptor

CODDOU, Claudio; Sandoval, Rodrigo; Jose Hevia, Maria; Stojilkovic, Stanko S.

Article ISI SCOPUS
NEUROSCIENCE LETTERS  (2019)

Chronic Fluoxetine Treatment Induces Maturation-Compatible Changes in the Dendritic Arbor and in Synaptic Responses in the Auditory Cortex

Ampuero, Estibaliz; Cerda, Mauricio; hartel, Steffen; Javier Rubio, Francisco; Massa, Solange; Cubillos, Paula; Abarza-Cataln, Lorena; Sandoval, Rodrigo; Galaburda, Albert M.; Wyneken, Ursula

Article ISI SCOPUS
FRONTIERS IN PHARMACOLOGY  (2019)

Biomonitoring of blood cholinesterases and acylpeptide hydrolase activities in rural inhabitants exposed to pesticides in the Coquimbo Region of Chile

Ramirez-Santana, M; Farias-Gomez, C; Zuniga-Venegas, L; Sandoval, R; Roeleveld, N; van der Velden, K; Scheepers, PTJ; Pancetti, F

Article ISI SCOPUS
PLOS ONE  (2018)

In Vivo Sub-chronic Treatment with Dichlorvos in Young Rats Promotes Synaptic Plasticity and Learning by a Mechanism that Involves Acylpeptide Hydrolase Instead of Acetylcholinesterase Inhibition. Correlation with Endogenous beta-Amyloid Levels

García-Rojo G.; Gámiz F.; Ampuero E.; Rojas-Espina D.; Sandoval R.; Rozas C.; Morales B.; Wyneken U.; Pancetti F.

Article ISI SCOPUS
FRONTIERS IN PHARMACOLOGY  (2017)

In Vivo Sub-chronic Treatment with Dichlorvos in Young Rats Promotes Synaptic Plasticity and Learning by a Mechanism that Involves Acylpeptide Hydrolase Instead of Acetylcholinesterase Inhibition. Correlation with Endogenous β-Amyloid Levels.

García-Rojo, Gonzalo; Gámiz, Fernando; Ampuero, Estíbaliz; Rojas-Espina, Daniel; Sandoval, Rodrigo; Rozas, Carlos; Morales, Bernardo; Wyneken, Ursula; Pancetti, Floria

Article
Frontiers in pharmacology  (2017)

Assessing biomarkers and neuropsychological outcomes in rural populations exposed to organophosphate pesticides in Chile - study design and protocol

Ramirez-Santana, M; Zuniga, L.; Corral, S; Sandoval, R; Scheepers, PTJ; van der Velden, K; Roeleveld, N; Pancetti F.

Article ISI SCOPUS
BMC Public Health  (2015)

Catalytic autoantibodies against myelin basic protein (MBP) isolated from serum of autistic children impair in vitro models of synaptic plasticity in rat hippocampus

Gonzalez-Gronow, M; Cuchacovich M.; Francos, R; Cuchacovich, S; Blanco A.; Sandoval, R; Gomez, CF; Valenzuela, JA; Ray, R.; Pizzo, SV

Article ISI SCOPUS
Journal of Neuroimmunology  (2015)

Impaired learning resulting from Respiratory Syncytial Virus infection

Espinoza, JA; Bohmwald, K; Cespedes, PF; Gomez RS; Riquelme, SA; Cortes, CM; Valenzuela, JA; Sandoval, RA; Pancetti, FC; Bueno, SM; Riedel, CA; Kalergis, AM

Article ISI SCOPUS
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA  (2013)

Impaired learning resulting from Respiratory Syncytial Virus infection

Espinoza, JA; Bohmwald, K; Cespedes, PF; Gomez, RS; Riquelme, SA; Cortes, CM; Valenzuela, JA; Sandoval, RA; Pancetti, FC; Bueno, SM; Riedel, CA; Kalergis, AM

Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA  (2013)

Long-term fluoxetine treatment induces input-specific LTP and LTD impairment and structural plasticity in the CA1 hippocampal subfield

Rubio, FJ; Ampuero E.; Sandoval, R; Toledo, J; Pancetti F.; Wyneken, U

Article ISI SCOPUS
Frontiers in Cellular Neuroscience  (2013)

Neurological and neuropsychological deterioration in artisanal gold miners from the town of Andacollo, Chile

Corral, S; Sáez D; Lam, G; Lillo, P.; Sandoval, R; Lancellotti D.; Radon K.; Zuniga, L.; Moraga D.; Pancetti F.

Article ISI SCOPUS
Toxicological and Environmental Chemistry  (2013)

Synaptic localization of acylpeptide hydrolase in adult rat telencephalon

Sandoval, R; Navarro, S; Garcia-Rojo, G; Calderôn R.; Pedrero A.; Sandoval, S; Wyneken, U; Pancetti F.

Article ISI SCOPUS
Neuroscience Letters  (2012)

Homeostatic NMDA receptor down-regulation via brain derived neurotrophic factor and nitric oxide-dependent signalling in cortical but not in hippocampal neurons

Sandoval, R; González A; Caviedes A; Pancetti F.; Smalla, KH; Kaehne T,; Michea, L.; Gundelfinger ED; Wyneken, U

Article ISI SCOPUS
Journal of Neurochemistry  (2011)

Effect of short-term exposure to dichlorvos on synaptic plasticity of rat hippocampal slices: Involvement of acylpeptide hydrolase and alpha(7) nicotinic receptors

Olmos, C; Sandoval, R; Rozas C.; Navarro, S; Wyneken, U; Zeise, M; Morales, B; Pancetti F.

Article ISI SCOPUS
TOXICOLOGY AND APPLIED PHARMACOLOGY  (2009)

Antagonistic effects of TrkB and p75(NTR) on NMDA receptor currents in post-synaptic densities transplanted into Xenopus oocytes

Sandoval M.; Sandoval, R; Thomas, U; Spilker, C; Smalla, KH; Falcon R.; Marengo, JJ; Calderôn R.; Saavedra V.; Heumann, R; Bronfman, F; Garner, CC; Gundelfinger ED; Wyneken, U

Article ISI SCOPUS
JOURNAL OF NEUROCHEMISTRY  (2007)

Status epilepticus induces region-specific changes in dendritic spines, dendritic length and TrkB protein content of rat brain cortex

Ampuero E.; Dagnino-Subiabre, A; Sandoval, R; Zepeda-Carreno, R; Sandoval, S; Viedma, A; Aboitiz F.; Orrego F.; Wyneken, U

Article ISI SCOPUS
BRAIN RESEARCH  (2007)

Protein kinase CK2 in postsynaptic densities: phosphorylation of PSD-95/SAP90 and NMDA receptor regulation

Soto, D; Pancetti F.; Marengo, JJ; Sandoval M.; Sandoval, R; Orrego F.; Wyneken, U

Article ISI
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS  (2004)

Epilepsy-induced changes in signaling systems of human and rat postsynaptic densities

Wyneken, U; Marengo, JJ; Villanueva, S.; Soto, D; Sandoval, R; Gundelfinger ED; Orrego F.

Article ISI SCOPUS
EPILEPSIA  (2003)

Abstract (2)

Assessing exposure to organophosphate pesticides, biomarkers and neuropsychological outcomes in rural populations of Chile

Ramirez-Santana, M; Zuniga, L.; Corral, S; Sandoval, R; Pancetti F.

Abstract ISI
NEUROTOXICOLOGY AND TERATOLOGY  (2015)

Respiratory Syncytial Virus infection in mice reduces spatial learning capacity and long term potentiation.

Espinoza J.; Cortes C.; Valenzuela J.; Sandoval, R; Gomez, R; Cespedes P; Pancetti F.; Riedel C.; Kalergis, A

Abstract ISI
JOURNAL OF IMMUNOLOGY  (2012)

Proyecto (3)

Role Of Acylpeptide Hydrolase In Synaptic Function During The Ontogeny Of Sprague- Dawley Rats. Involvement Of Endogenous Beta- Amyloid Peptide Levels And alpha-7 Nicotinic Receptors In This Mechanism

Pancetti Vaccari, Floria Carla; Sandoval, Rodrigo

Proyecto
 (2014)

Autoantibodies isolated from the serum of autistic children impair in vitro models of synaptic plasticity: role of the voltage- dependent anion channel (VDAC), hexokinase-I and myelin basic protein autoantibodies in this mechanism

Gonzalez-Gronow, Mario; Sandoval, Rodrigo

Proyecto
 (2013)

Physiological role of acylpeptide hydrolase in the clearence of beta-amyloid and its implicance as a putative new taget for Alzheimer´s Disease

Sandoval Guzmán, Rodrigo Andrés

Proyecto
 (2012)

21
Rodrigo Sandoval

Director de departamento

Ciencias Biomédicas

UNIVERSIDAD CATOLICA DEL NORTE

Coquimbo, Chile

17
Inge Wyneken

Full Professor

Medicina

UNIVERSIDAD DE LOS ANDES

Santiago, Chile

9
Floria Pancetti

Director de Departamento

Ciencias Biomédicas

UNIVERSIDAD CATOLICA DEL NORTE

Coquimbo, Chile

4
Mauricio Sandoval

Lab Manager

Facultad de Medicina

Pontificia Universidad Católica de Chile

Santiago, Chile

3
sebastian corral

Psicologo/investigador

Psiquiatría

Universidad de Chile

santiago, Chile

3
Liliana Zúñiga

Research director

Universidad Católica del Maule

Talca, Chile

2
Dagoberto Soto

Investigador

Universidad Católica de Chile

santiago, Chile

2
Rodrigo Calderón

Estudiante doctorado

Ciencias Biomedicas

Universidad Católica del Norte

Coquimbo, Chile

2
estibaliz ampuero

Profesor Asistente

Facultad de Química y Biología

Universidad de Santiago de Chile

Santiago, Chile

1
Daniel Moraga

Profesor Asociado

Medicina

Universidad de Tarapacá

Arica, Chile

1
Gonzalo García

Académico

Universidad de La Serena

La Serena, Chile

1
Claudio Coddou

Profesor Asociado

Departamento de Ciencias Biomédicas

Universidad Católica del Norte

Coquimbo, Chile

1
Claudio Coddou

Profesor Asociado

Ciencias Biomédicas

Universidad Católica del Norte

Coquimbo, Chile

1
Cristian Farías

Bioquímico de Investigación

Ciencias Biomédicas

Universidad Católica del Norte

Chile, Chile

1
Muriel Ramirez

Profesor Titular

Salud Pública

Universidad Catolica del Norte

Coquimbo, Chile

1
Mauricio Cerda

Assistant Professor (appointed)

Programa de Anatomía y Biología del Desarrollo

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Maria Hevia

Prosefora

Ciencias Biomedicas

Universidad Cátolica del Norte

Coquimbo, Chile

1
Karen Bohmwald

Académico Investigador

Universidad Autónoma de Chile

Santiago, Chile

1
Steffen Härtel

Full Professor

Instituto de Ciencias Biomédicas

University of Chile

Santiago, Chile

1
Alexis Kalergis

Full Professor

Microbiología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE. FACULTAD DE CIENCIAS BIOLÓGICAS

Santiago, Chile

1
Claudia Riedel

Full Professor

Life Sciences

Universidad Andres Bello

Santiago, Chile

1
Alexies Dagnino

Full Professor

Physiology

UNIVERSIDAD DE VALPARAÍSO

Valparaíso, Chile

1
Susan Bueno

Profesor Asociado

Genética Molecular y Microbiología

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

1
Luis Michea

PROFESOR ASOCIADO

PROGRAMA FISIOLOGIA Y BIOFISICA

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Lorena Abarzúa

Investigador

Medicina

Universidad de los Andes

Santiago, Chile

1
Patricia Lillo

Assistant professor

Neurología sur

Departamento de Neurología Sur. Facultad de Medicina. Universidad de Chile

Santiago, Chile

1
Bernardo Morales

Profesor titular

Biologia

Universidad de Santiago de Chile

Santiago, Chile

1
Marc Zeise

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

1
Francisco Aboitiz

Profesor

Psychiatry

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

santiago, Chile

1
Francisca Bronfman

Full Professor

Instituto de Ciencias Biomédicas

Universidad Andrés Bello

Santiago, Chile

1
Domingo Lancellotti

Académico

Departamento de Salud Pública

Universidad Católica del Norte

Coquimbo, Chile

1
Ariel Caviedes

Postdoctorado

Escuela de psicología

Universidad Adolfo Ibánez

Santiago, Chile

1
Andrés González

Staff Scientist

Neurociencias

Instituto de Neurociencia Biomédica

Santiago, Chile