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Bernardo Enrique Morales Muñoz

Profesor titular

Universidad de Santiago de Chile

Santiago, Chile

Líneas de Investigación


Neurociencia; Fisiología; Biofísica; plasticidad sinaptica

Educación

  •  Biologo Marino, UNIVERSIDAD DE CONCEPCION. Chile, 1984
  •  Fisiologia, UNIVERSIDAD DE CHILE. Chile, 1987
  •  Fisiologia, UNIVERSIDAD DE CHILE. Chile, 1995
  •  Neurociencia, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1996
  •  Neuroscience, JOHNS HOPKINS UNIVERSITY. Estados Unidos, 1998

 

Article (36)

A Review of the Actions of Endogenous and Exogenous Vasoactive Substances during the Estrous Cycle and Pregnancy in Rats
Atomoxetine Reestablishes Long Term Potentiation in a Mouse Model of Attention Deficit/Hyperactivity Disorder
Facts and hypotheses about the programming of neuroplastic deficits by prenatal malnutrition.
Antinociception Induced by Copper Salt Revisited: Interaction with Ketamine in Formal inInduced Intraplantar and Orofacial Pain in Mice
Copper-induced activation of TRP channels promotes extracellular calcium entry and activation of CaMK, PKA, PKC, PKG and CBLPK leading to increased expression of antioxidant enzymes in Ectocarpus siliculosus
Single and Repeated Administration of Methylphenidate Modulates Synaptic Plasticity in Opposite Directions via Insertion of AMPA Receptors in Rat Hippocampal Neurons
Sub-chronic Treatment with Dichlorvos in Young Rats Promotes Synaptic Plasticity and Learning by a Mechanism that Involves Acylpeptide Hydrolase Instead of Acetylcholinesterase Inhibition. Correlation with Endogenous β-Amyloid Levels.
Dopamine receptor D5 deficiency results in a selective reduction of hippocampal NMDA receptor subunit NR2B expression and impaired memory
Copper-induced activation of TRP channels promotes extracellular calcium entry, activation of CaMs and CDPKs, copper entry and membrane depolarization in Ulva compressa
Methylphenidate amplifies long-term potentiation in rat hippocampus CA1 area involving the insertion of AMPA receptors by activation of beta-adrenergic and D1/D5 receptors
Methylphenidate has long-lasting metaplastic effects in the prefrontal cortex of adolescent rats
a new semisynthetic derivative of sauroine induces ltp in hippocampal slices and improves learning performance in the morris water maze
MAP1B-dependent Rac activation is required for AMPA receptor endocytosis during long-term depression
Acutely applied MDMA enhances long-term potentiation in rat hippocampus involving D1/D5 and 5-HT2 receptors through a polysynaptic mechanism
Copper-induced intracellular calcium release requires extracellular calcium entry and activation of L-type voltage-dependent calcium channels in Ulva compressa
Cross Talk among Calcium, Hydrogen Peroxide, and Nitric Oxide and Activation of Gene Expression Involving Calmodulins and Calcium-Dependent Protein Kinases in Ulva compressa Exposed to Copper Excess
Differential Expression of Potassium Channels in Placentas from Normal and Pathological Pregnancies: Targeting of the K-ir 2.1 Channel to Lipid Rafts
Zinc enhances long-term potentiation through P2X receptor modulation in the hippocampal CA1 region
Co-occurring increases of calcium and organellar reactive oxygen species determine differential activation of antioxidant and defense enzymes in Ulva compressa (Chlorophyta) exposed to copper excess
Co-occurring increases of calcium and organellar reactive oxygen species determine differential activation of antioxidant and defense enzymes in Ulva compressa (Chlorophyta) exposed to copper excess.
MDMA ("ecstasy") impairs learning in the Morris Water Maze and reduces hippocampal LTP in young rats
Effect of short-term exposure to dichlorvos on synaptic plasticity of rat hippocampal slices: Involvement of acylpeptide hydrolase and alpha(7) nicotinic receptors
The release of sympathetic neurotransmitters is impaired in aged rats after an inflammatory stimulus: A possible link between cytokine production and sympathetic transmission
ATP and adenosine trigger the interaction of plasma membrane IP3 receptors with protein kinase A in oviductal ciliated cells
Methylphenidate improves cue navigation in the Morris water maze in rats
Regulation of the immunoexpression of aquaporin 9 by ovarian hormones in the rat oviductal epithelium
Plasma and intracellular membrane inositol 1,4,5-trisphosphate receptors mediate the Ca2+ increase associated with the ATP-induced increase in ciliary beat frequency
Prediction of synergism on frequency of responses in the attojoule range
S-Methylcysteine may be a causal factor in monohalomethane neurotoxicity
Histidine 140 plays a key role in the inhibitory modulation of the P2X(4) nucleotide receptor by copper but not zinc
Neuromodulator role of zinc and copper during prolonged ATP applications to P2X(4) purinoceptors
Dark rearing alters the development of GABAergic transmission in visual cortex
Platelet activating factor increases ciliary activity in the hamster oviduct through epithelial production of prostaglandin E-2
Platelet activating factor increases ciliary activity in the hamster oviduct through epithelial production of prostaglandin E2
Functional cross talk after activation of P2 and P1 receptors in oviductal ciliated cells
Zinc and copper modulate differentially the P2X(4) receptor

Abstract (4)

Sub-acute exposure to dichlorvos favors long-term potentiation trhough a mechanism that involves rectangle(7) nicotinic receptors and acyleptide hydrolase inhibition
A physical chemistry theory of synergism on ciliated cell motility
Synergism on ciliary activity induced by ATP and adenosine depends on a reciprocal modulation of their transduction pathways
Transduction mechanisms associated with activation of P-1 and P-2 purinoceptors in oviductal ciliated cells: functional cross-talk between both pathways

BookSection (2)

Temática 6 Aprendizaje y plasticidad
Reciprocal synergism at early stages of transduction pathways allows efficient cell signaling. Chapter 4

Patent (2)

COMPUESTOS DERIVADOS DE SAUROINA O SUS FORMAS HIDROACIDAS O SUS FORMAS OPTICAMENTE ACTIVAS Y SUS SALES; COMPUESTO DIACETIL-SAUROINA (DAS); Y PROCESO PARA LA OBTENCION DEL COMPUESTO DIACETIL-SAUROINA (DAS) O SUS FORMAS HIDROACIDAS O SUS FORMAS OPTICAMENTE ACTIVAS Y SUS SALES.
METODO PARA INCREMENTAR LA EFICIENCIA METABOLICA O TASA DE CONVERSION BIOLOGICA DE SALMONIDOS EN CONDICIONES DE CULTIVO INTENSIVO QUE COMPRENDE ALIMENTAR CON UNA COMBINACION O MEZCLAS DE POLISACARIDOS PROVENIENTES DE MACROCYSTIS PYRIPHERA, SARCOTHALIA CRISPATA, Y GIGARTINA SKOTTSBERGII.

Proyecto (16)

Effect of methylphenidate on behaviour and synaptic plasticity in a murine model of attention deficit-hyperactivity disorder
COPPER-INDUCED EXTRACELLULLAR CALCIUM ENTRY, INTRACELLULAR CALCIUM RELEASE AND ACTIVATION OF GENE EXPRESSION OF ANTIOXIDANT ENZYMES VIA CAMS, CDPKS AND CBLPKS IN THE MARINE MACROALGA ECTOCARPUS SILICULOSUS.
COPPER-INDUCED ACTIVATION OF TRANSIENT RECEPTOR POTENTIAL (TRP) AND VOLTAGE-DEPENDENT CALCIUM CHANNELS (VDCC) AND THEIR REGULATION BY SECRETED REDOX COMPOUNDS, NO, CALMODULINS AND CDPKS AND IN THE MARINE ALGA ULVA COMPRESSA
Evaluación y selección de fotoquímicos con propiedades antibactericidas e inmunológicas destinados a la formulación de dietas
Evolutionary adaptions of voltage dependent potassium channels from an antarctic organism
ROLE OF GABAA CHANNELS IN THE AXON INITIAL SEGMENT IN EPILEPSY
STUDY OF THE PHYSIOLOGICAL ROLE OF TRP CHANNELS IN THERMAL SENSORY TRANSDUCTION AND SYNAPTIC PLASTICITY
CELLULAR AND MOLECULAR BASES OF THE EFFECT OF METHYLPHENIDATE ON THE SYNAPTIC PLASTICITY IN HIPPOCAMPUS AND PREFRONTAL CORTEX.
Consolidación de la red y ampliación en las investigaciones en el campo de los productos naturales y las neurociencias
Desarrollo e implementación de herramientas innovadoras para la evaluación de estrés en salmonidos destinadas a aumentar la productividad
Fortalecimiento del claustro Académico del Departamento de Biología para la Creación de un Doctorado en Neurociencias en la Universidad de Santiago de Chile
MOLECULAR AND CELLULAR BASES OF NEUROPATHIC PAIN=> ROLE OF IKD IN COLD-INDUCED ALLODYNIA FOLLOWING INJURY IN PRIMARY SENSORY NEURONS
PAPEL DEL DOMINIO N-TERMINAL EN LA OLIGOMERIZACION, TRAFICO Y FUNCION DEL CANAL IONICO TRPM8.
BASES CELULARES Y MOLECULARES DEL EFECTO DE MDMA (EXTASIS) SOBRE LA PLASTICIDAD SINAPTICA EN CORTEZA VISUAL E HIPOCAMPO
Consolidación del Doctorado en Biotecnología de la Universidad de Santiago de Chile
SENALES DE CALCIO Y ROS INDUCIDAS POR COBRE EN EL ALGA MARINA ULVA COMPRESSA (CHLOROPHYTA) Y SU PARTICIPACION EN LA ACTIVACION DE GENES IMPLICADOS EN LA TRANSDUCCION DE SENALES Y EN LA RESPUESTA ANTIOXIDANTE.

Review (5)

A Review of Endothelium-Dependent and -Independent Vasodilation Induced by Phytochemicals in Isolated Rat Aorta
Noncholinesterase effects induced by organophosphate pesticides and their relationship to cognitive processes: Implication for the action of acylpeptide hydrolase
Maturation of GABAergic transmission and the timing of plasticity in visual cortex
Principles: Mechanisms and modeling of synergism in cellular responses
Critical period of cortical plasticity
46
Bernardo Morales

Profesor titular

Biologia

Universidad de Santiago de Chile

Santiago, Chile

11
Nelson Barrera

Associate Professor

Physiology

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

8
Marc Zeise

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

7
Floria Pancetti

Director de Departamento

Ciencias Biomédicas

UNIVERSIDAD CATOLICA DEL NORTE

Coquimbo, Chile

5
Alejandra Moenne

Profesor Titular

Biologia

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

4
Sebastián Loyola

Académico adjunto

Ciencias de la Salud

Universidad Católica Silva Henriquez

Santiago, Chile

4
DARWIN CONTRERAS

Profesor por horas

Facultad de Química y Biología

Universidad de Santiago de Chile

Santiago, Chile

3
Alberto González

Académico

Biología

Universidad de Santiago de Chile

Estación Central, Chile

3
Patricio Rojas

Assistant Professor

Departamento de Biologia

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

3
Gonzalo Ugarte

Asistente de Investigación

Biología

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

3
Claudio Coddou

Profesor Asociado

Ciencias Biomédicas

Universidad Católica del Norte

Coquimbo, Chile

3
Claudio Coddou

Profesor Asociado

Departamento de Ciencias Biomédicas

Universidad Católica del Norte

Coquimbo, Chile

2
Inge Wyneken

Full Professor

Medicina

UNIVERSIDAD DE LOS ANDES

Santiago, Chile

2
Claudio Acuña

Profesosr Asociado

Biología

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

2
Claudio Sáez

Director General

centro HUB AMBIENTAL UPLA

UNIVERSIDAD DE PLAYA ANCHA DE CIENCIAS DE LA EDUCACION

Valparaíso, Chile

2
claudia carvallo

Investigación

Biología

Universidad de Chile

Santiago, Chile

2
Luis Constandil

Profesor Titular

Biología

Universidad de Santiago de Chile

Santiago, Chile

2
Christian Gonzalez

Full Professor

Biology

Universidad de Chile

Santiago, Chile

2
Juan Correa

Full Profesor

Ecology

Pontificia Universidad Catolica de Chile

Santiago, Chile

2
Miguel Reyes

Full Professor

Facultad de Ciencias Médicas

UNIVERSIDAD DE SANTIAGO DE CHILE, FACULTAD DE CIENCIAS MÉDICAS, ESCUELA DE MEDICINA

Santiago, Chile

2
Ricardo Delgado

Profesor Adjunto

Biología

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS, DEPARTAMENTO DE BIOLOGIA

Santiago, Chile

1
Julio Benites

Profesor Titular

Química y Farmacia

Universidad Arturo Prat

Iquique, Chile

1
Alexies Dagnino

Full Professor

Physiology

UNIVERSIDAD DE VALPARAÍSO

Valparaíso, Chile

1
MARCELA KNOX

Asistente Investigación Laboratorio Farmacología

Ciencias Farmacéuticas

Universidad de Valparaíso

Valparaiso, Chile

1
Luis Aguayo

Full Professor

Department of Physiology

Universidad de Concepcion

Concepcion, Chile

1
Héctor Burgos

DOCENTE E INVESTIGADOR

FACULTAD DE CIENCIAS

Universidad Mayor, Chile

SANTIAGO, Chile

1
Rodrigo Pacheco

Associate Investigator; Head of the Laboratory of Neuroimmunology

Fundación Ciencia para la Vida

Santiago, Chile

1
Jimmy Stehberg

Associate Professor

Biological Sciences

UNIVERSIDAD ANDRÉS BELLO

SANTIAGO, Chile

1
AMPARO CASTILLO

DOCENTE

PSICOLOGÍA

Universidad Santo Tomás

SANTIAGO, Chile

1
Kevin Maisey

Profesor Asistente

Centro de Biotecnología Acuícola

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

1
Lida Fuentes

Researcher

Centro Regional de Estudios en Alimentos Saludables

Valparaiso, Chile

1
Carlos Rozas

Profesor asistente

Biologia

Universidad de Santiago de Chile

Santiago, Chile

1
Ricardo Fernandez

Profesor Asociado A

Salud

Universidad de Los Lagos

Osorno, Chile

1
Rodrigo Sandoval

Director de departamento

Ciencias Biomédicas

UNIVERSIDAD CATOLICA DEL NORTE

Coquimbo, Chile

1
Carmen Imarai

Profesor Titular

Biología

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

1
Ricardo Fernández

Associate Professor

Health

Universidad de Los Lagos

Osorno, Chile

1
Ricardo Piña

Profesor Asociado

Biología

Universidad Metropolitana de Ciencias de la Educación

Ñuñoa , Chile

1
Felipe Gordillo

UNIVERSIDAD CATÒLICA DEL MAULE

Talca, Chile

1
Mariana Rios

Investigador

Facultad de Ciencias Biológicas

pontificia Universidad Católica de Chile

Santiago, Chile

1
Marcela Hermoso

Full Professor

School of Medicine

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Rodrigo Contreras

Postdoc

Departamento de Biología

USACH

Santiago, Chile