Man

Ricardo Alfonso Delgado Arriagada

Profesor Adjunto

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS, DEPARTAMENTO DE BIOLOGIA

Santiago, Chile

Líneas de Investigación


Neurobiologia; Transduccion sensorial; Biofisica;

Educación

  •  Biologia, UNIVERSIDAD DE CHILE. Chile, 1984
  •  Ciencias Biologicas, UNIVERSIDAD DE CHILE. Chile, 1991
  •  Natural Sciences, Leibniz Universitat Hannover. Alemania, 2011

Experiencia Académica

  •   Profesor Adjunto Other

    UNIVERSIDAD DE CHILE

    Ciencias

    Chile

    2004 - A la fecha

Formación de Capital Humano


Tesis de Doctorado
Cesar Astorga
Instituto de Ciencias Biomédicas



 

Article (36)

Light-Induced Opening of the TRP Channel in Isolated Membrane Patches Excised From Photosensitive Microvilli From Drosophila Photoreceptors

Delagado, Ricardo; Delgado, Maria Graciela; Bastin-Héline, Lucie; Glavic, Alvaro; O'Day, Peter M; Bacigalupo, Juan

Article
NEUROSCIENCE  (2019)

Chaski, a novel Drosophila lactate/pyruvate transporter required in glia cells for survival under nutritional stress

Delgado, MG; Oliva, C; Lopez, E; Ibacache, A; GALAZ, A; Delgado, R; Barros, LF; Sierralta, J

Article ISI SCOPUS
SCIENTIFIC REPORTS  (2018)

Single and Repeated Administration of Methylphenidate Modulates Synaptic Plasticity in Opposite Directions via Insertion of AMPA Receptors in Rat Hippocampal Neurons

Carvallo, C; Contreras, D; Ugarte, G; Delgado, R; Pancetti, F; Rozas, C; Pina, R; Constandil, L; Zeise, ML; Morales, B

Article
Frontiers in Pharmacology  (2018)

A CLCA regulatory protein present in the chemosensory cilia of olfactory sensory neurons induces a Ca2+ -activated Cl- current when transfected into HEK293

Mura, CV; Delgado, R; Delgado, MG; Restrepo, D; Bacigalupo, J

Article ISI SCOPUS
BMC Neuroscience  (2017)

Drosophila Atlastin in motor neurons is required for locomotion and presynaptic function

De Gregorio, C; Delgado, R; Ibacache, A; Sierralta, J; Couve, A

Article ISI SCOPUS
Journal of Cell Science  (2017)

Energy Requirements of Odor Transduction in the Chemosensory Cilia of Olfactory Sensory Neurons Rely on Oxidative Phosphorylation and Glycolytic Processing of Extracellular Glucose

Villar, Pablo S.; Delgado, Ricardo; Vergara, Cecilia; Reyes, Juan G.; Bacigalupo, Juan

Article ISI SCOPUS
JOURNAL OF NEUROSCIENCE  (2017)

Presynaptic DLG regulates synaptic function through the localization of voltage-activated Ca2+ Channels

Astorga, César; Jorquera, Ramón A.; Ramírez, Mauricio; Kohler, Andrés; López, Estefanía; Delgado, Ricardo; Córdova, Alex; Olguín, Patricio; Sierralta, Jimena.

Article ISI SCOPUS
SCIENTIFIC REPORTS  (2016)

Single Ca(2+)-activated Cl(-) Channel Currents Recorded From Toad Olfactory Cilia

Delagado, Ricardo; Mura, Casilda; Bacigalupo, Juan

Article
BMC NEUROSCIENCE  (2016)

Copper enhances cellular and network excitabilities, and improves temporal processing in the rat hippocampus

Maureira C.; Letelier, JC; Alvarez, O; Delgado, R; Vergara C.

Article ISI SCOPUS
European Journal of Neuroscience  (2015)

Methylphenidate amplifies long-term potentiation in rat hippocampus CA1 area involving the insertion of AMPA receptors by activation of beta-adrenergic and D1/D5 receptors

Rozas C.; Carvallo C.; Contreras D.; Carreo, M.; Ugarte, G.; Delgado, R; Zeise M.L.; Morales, B

Article ISI SCOPUS
Neuropharmacology  (2015)

Methylphenidate amplifies long-term potentiation in rat hippocampus CA1 area involving the insertion of AMPA receptors by activation of beta-adrenergic and D1/D5 receptors

Rozas C; Carvallo, C; Contreras D.; Carreo, M.; Ugarte G.; Delgado R.; Zeise, M.L.; Morales B

Article
Neuropharmacology  (2015)

a new semisynthetic derivative of sauroine induces ltp in hippocampal slices and improves learning performance in the morris water maze

Vallejo M.; Loyola S; Contreras D.; Ugarte, G.; Cifuente, D; Ortega, G; Cabrera, JL; Zeise, M; Tonn, C.; Carreño, M; Delgado, R; Morales, B; Agnese, M

Article ISI SCOPUS
JOURNAL OF NEUROCHEMISTRY  (2014)

Diacylglycerol Activates the Light-Dependent Channel TRP in the Photosensitive Microvilli of Drosophila melanogaster Photoreceptors

Delgado, R; Muñoz Y.; Pena-Cortes, H; Giavalisco, P; Bacigalupo, J

Article ISI SCOPUS
JOURNAL OF NEUROSCIENCE  (2014)

Overexpression of Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels into the Ventral Tegmental Area Increases the Rewarding Effects of Ethanol in UChB Drinking Rats

Rivera-Meza, M; Quintanilla, ME; Bustamante D.; Delgado, R; Buscaglia M.; Herrera-Marschitz, M

Article ISI SCOPUS
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH  (2014)

Transduction for pheromones in the main olfactory epithelium is mediated by the Ca2+ -activated channel TRPM5.

López, Fabián; Delgado, Ricardo; López, Roberto; Bacigalupo, Juan; Restrepo, Diego

Article
The Journal of neuroscience : the official journal of the Society for Neuroscience  (2014)

Transduction for Pheromones in the Main Olfactory Epithelium Is Mediated by the Ca2+-Activated Channel TRPM5

López F; Delgado, R; Lopez R.; Bacigalupo, J; Restrepo, D.

Article ISI SCOPUS
JOURNAL OF NEUROSCIENCE  (2014)

Fatty acid composition of Drosophila photoreceptor light-sensitive microvilli

Muñoz, Yorka; Fuenzalida, Karen; Bronfman, Miguel; Gatica, Arnaldo; Sepúlveda, Marcelo; Bacigalupo, Juan; Roth, Alejandro D.; Delgado, Ricardo

Article ISI SCIELO SCOPUS
Biological Research  (2013)

Altered Voltage Dependent Calcium Currents in a Neuronal Cell Line Derived From the Cerebral Cortex of a Trisomy 16 Fetal Mouse, an Animal Model of Down Syndrome

Acuna M.A.; Perez-Nunez R.; Noriega, J; Cárdenas A.M.; Bacigalupo, J; Delgado, R; Arriagada C.; Segura-Aguilar, J; Caviedes R.; Caviedes P.

Article ISI SCOPUS
Neurotoxicity Research  (2012)

Altered voltage dependent calcium currents in a neuronal cell line derived from the cerebral cortex of a trisomy 16 fetal mouse, an animal model of Down syndrome.

Acuña, Mario A; Pérez-Nuñez, Ramón; Noriega, Jorge; Cárdenas, Ana María; Bacigalupo, Juan; Delgado, Ricardo; Arriagada, Christian; Segura-Aguilar, Juan; Caviedes, Raúl; Caviedes, Pablo

Article
Neurotoxicity research  (2012)

Unitary Recordings of TRP and TRPL Channels From Isolated Drosophila Retinal Photoreceptor Rhabdomeres: Activation by Light and Lipids

Delgado, R; Bacigalupo, J

Article ISI SCOPUS
JOURNAL OF NEUROPHYSIOLOGY  (2009)

DLGS97/SAP97 is developmentally upregulated and is required for complex adult behaviors and synapse morphology and function

Mendoza-Topaz, C; Urra, F.; Barria, R; Albornoz, V; Ugalde, D; Thomas, U; Gundelfinger ED; Delgado, R; Kukuljan M.; Sanxaridis, PD; Tsunoda, S; Ceriani, MF; Budnik, V; Sierralta, J

Article ISI SCOPUS
JOURNAL OF NEUROSCIENCE  (2008)

Scaffolding proteins in highly purified rat olfactory cilia membranes

Saavedra, MV; Smalla, KH; Thomas, U; Sandoval, S; Olavarria, K; Castillo, K; Delgado, MG; Delgado, R; Gundelfinger ED; Bacigalupo, J; Wyneken, U

Article ISI SCOPUS
NEUROREPORT  (2008)

Copper and zinc as modulators of neuronal excitability in a physiologically significant concentration range

Aedo, F; Delgado, R; Wolff, D; Vergara C.

Article ISI SCOPUS
NEUROCHEMISTRY INTERNATIONAL  (2007)

Plasma membrane Ca2+-ATPase in the cilia of olfactory receptor neurons: Possible role in Ca2+ clearance

Castillo, K; Delgado, R; Bacigalupo, J

Article ISI SCOPUS
EUROPEAN JOURNAL OF NEUROSCIENCE  (2007)

Bridging behavior and physiology: Ion-channel perspective on mushroom body-dependent olfactory learning and memory in Drosophila

Gasque, G; Labarca P.; Delgado, R; Darszon, A

Article ISI
JOURNAL OF CELLULAR PHYSIOLOGY  (2006)

Divalent cations as modulators of neuronal excitability: Emphasis on copper and zinc

Delgado, R; Vergara C.; Wolff, D

Article ISI SCIELO
BIOLOGICAL RESEARCH  (2006)

Quiescence induced by iron challenge protects neuroblastoma cells from oxidative stress

Mura, CV; Delgado, R; Aguirre P.; Bacigalupo, J; Nunez, MT

Article ISI SCOPUS
JOURNAL OF NEUROCHEMISTRY  (2006)

Cyclic AMP cascade mediates the inhibitory odor response of isolated toad olfactory receptor neurons

Madrid R.; Delgado, R; Bacigalupo, J

Article ISI SCOPUS
JOURNAL OF NEUROPHYSIOLOGY  (2005)

Putative ClC-2 chloride channel mediates inward rectification in Drosophila retinal photoreceptors

Ugarte, G.; Delgado, R; O'Day, PM; Farjah, F; Cid, LP; Vergara C.; Bacigalupo, J

Article ISI SCOPUS
JOURNAL OF MEMBRANE BIOLOGY  (2005)

Cilium-attached and excised patch-clamp recordings of odourant-activated Ca-dependent K channels from chemosensory cilia of olfactory receptor neurons

Delgado, R; Bacigalupo, J

Article ISI SCOPUS
EUROPEAN JOURNAL OF NEUROSCIENCE  (2004)

Orientation of Arabidopsis thaliana KAT1 channel in the plasma membrane

Mura, CV; Cosmelli, D; Muñoz F; Delgado, R

Article ISI SCOPUS
JOURNAL OF MEMBRANE BIOLOGY  (2004)

Signaling through Gs alpha is required for the growth and function of neuromuscular synapses in Drosophila

Wolfgang, WJ; Clay, C; Parker, J; Delgado, R; Labarca P.; Kidokoro, Y; Forte, M

Article ISI SCOPUS
DEVELOPMENTAL BIOLOGY  (2004)

Synaptic vesicle pools and plasticity of synaptic transmission at the Drosophila synapse

Kidokoro, Y; Kuromi, H; Delgado, R; Maureira C.; Oliva, C; Labarca P.

Article ISI
BRAIN RESEARCH REVIEWS  (2004)

Presence of Ca(2+)-dependent K(+) channels in chemosensory cilia support a role in odor transduction

Delgado, R; Saavedra, MV; Schmachtenberg, O.; Sierralta, J; Bacigalupo, J

Article ISI SCOPUS
JOURNAL OF NEUROPHYSIOLOGY  (2003)

Inwardly rectifying K+ channels in spermatogenic cells: Functional expression and implication in sperm capacitation

Munoz-Garay, C; De la Vega-Beltran, JL; Delgado, R; Labarca P.; Felix, R; Darszon, A

Article ISI SCOPUS
DEVELOPMENTAL BIOLOGY  (2001)

Size of vesicle pools, rates of mobilization, and recycling at neuromuscular synapses of a Drosophila mutant, shibire

Delgado, R; Maureira C.; Oliva, C; Kidokoro, Y; Labarca P.

Article ISI SCOPUS
NEURON  (2000)

Abstract (6)

Cloning and Characterization of the Ca2+-activated Cl- Channel ClCa4l from Rat Olfactory Sensory Neurons

Mura, C; Delgado, R; Restrepo, D.; Bacigalupo, J

Abstract ISI
JOURNAL OF GENERAL PHYSIOLOGY  (2014)

Diacylglycerol Activates the Light-dependent Channels TRP and TRPL in Drosophila Photoreceptors

Delgado, R; Muñoz Y.; Pena-Cortes, H; Giavalisko, P; Bacigalupo, J

Abstract ISI
JOURNAL OF GENERAL PHYSIOLOGY  (2014)

Copper and zinc as modulators of neuronal excitability

Aedo, F; Delgado, R; Wolff, D; Vergara C.

Abstract ISI
PLACENTA  (2006)

Single-channel recordings of olfactory cilia transduction channels

Delgado, R; Bacigalupo, J

Abstract ISI
Chemical Senses  (2006)

Altered synaptic transmission and lack of post-tetanic potentiation in inositol polyphosphate 1-phosphatase mutant correlates with abnormal mobilization of the reserve pool of synaptic vesicles

Labarca P.; Delgado, R; Maureira C.; Oliva, C

Abstract ISI
JOURNAL OF PHYSIOLOGY-LONDON  (2000)

Vesicle recycling and synaptic transmission during prolonged synaptic activity in larval Drosophila motor endplates

Delgado, R; Kidokoro, Y; Labarca P.

Abstract ISI
JOURNAL OF PHYSIOLOGY-LONDON  (2000)

BookWhole (1)

TRP channels in visual transduction

Bacigalupo, J; Delgado, R; Muñoz Y.; O'Day P.

BookWhole SCOPUS
TRP Channels in Sensory Transduction  (2015)

Proyecto (8)

IDENTIFICATION AND CHARACTERIZATION OF A CA2 -ACTIVATED CL- CHANNEL OF RAT OLFACTORY CILIA.

FONDECYT (1100682)

Proyecto
2010-2014
Coinvestigador(a)

STUDY OF THE LIGHT-TRANSDUCCION, LIGHT-ADAPTATION AND RESPONSE DEACTIVATION MECHANISMS OF DROSOPHILA FOTORRECEPTORS BY MEANS OF SINGLE-CHANNEL RECORDINGS FROM THE PHOTOSENSITIVE MEMBRANE

FONDECYT (1100730)

Proyecto
2010-2014
Inv. Responsable

STUDY OF THE LIGHT-TRANSDUCCION, LIGHT-ADAPTATION AND RESPONSE DEACTIVATION MECHANISMS OF DROSOPHILA FOTORRECEPTORS BY MEANS OF SINGLE-CHANNEL RECORDINGS FROM THE PHOTOSENSITIVE MEMBRANE

FONDECYT (1100730)

Proyecto
2010-2014
Inv. Responsable

TRANSDUCCION EN FOTORRECEPTORES DE DROSOPHILA=> ESTUDIO A NIVEL DE CANAL UNICO DE LAS CONDUCTANCIAS DEPENDIENTES DE LUZ Y DE SU MECANISMO DE ACTIVACION EN FOTORRECEPTORES AISLADOS.

FONDECYT (1040772)

Proyecto
2004-2008
Inv. Responsable

MOVILIZACION DE VESICULAS SINAPTICAS EN LA JUNTURA NEUROMUSCULAR DE LA LARVA DE LA DROSOPHILA MELANOGASTER Y SU ROL EN LAS ALTERACIONES DE LA PLASTICIDAD SINAPTICA EN TRES MUTANTES NEUROLOGICOS.

FONDECYT (1000895)

Proyecto
2000-2002
Coinvestigador(a)

APRENDIZAJE Y RETENCION EN LA DROSOPHILA=> ESTUDIOS ELECTROFISIOLOGICOS EN INDIVIDUOS NORMALES Y EN MUTANTES NEUROLOGICOS.

FONDECYT (1950457)

Proyecto
1995-1998
Coinvestigador(a)

ESTUDIO DE LAS CONDUCTANCIAS DE MEMBRANA Y DE LA ADAPTACION EN NEURONAS OLFATORIAS DE VERTEBRADOS

FONDECYT (1930859)

Proyecto
1993-1996
Coinvestigador(a)

ESTUDIO DE CANALES IONICOS EN MEMBRANAS EXCITABLES DE POR NEUROTRANSMISORES Y SEGUNDOS MENSAJEROS EN LA CEPA NORMAL Y EN MUTANTES NEUROLOGICOS.

FONDECYT (1881167)

Proyecto
1988-1991
Coinvestigador(a)

39
Ricardo Delgado

Profesor Adjunto

Biología

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS, DEPARTAMENTO DE BIOLOGIA

Santiago, Chile

5
Pedro Labarca

Principal Research

Biology

CENTRO DE ESTUDIOS CIENTÍFICOS

Valdivia, Chile

5
Cecilia Vergara

Profesor Asociado

Biología

DEPARTAMENTO BIOLOGIA, FACULTAD DE CIENCIAS, U. DE CHILE

Santiago, Chile

4
Jimena Sierralta

Full Professor

Neuroscience

Faculty of Medicine, Universidad de Chile

Santiago, Chile

4
Carlos Maureira

Investigador Associated

Biology

Universidad de Chile

Santiago, Chile

3
Carolina Oliva

Investigador Asociado

Facultad de Medicina

Universidad Andrés Bello

Santiago, Chile

3
Gonzalo Ugarte

Asistente de Investigación

Biología

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

2
Bernardo Morales

Profesor titular

Biologia

Universidad de Santiago de Chile

Santiago, Chile

2
DARWIN CONTRERAS

Profesor por horas

Facultad de Química y Biología

Universidad de Santiago de Chile

Santiago, Chile

2
Karen Castillo

Académica Investigadora

,Centro de Investigación de Estudios Avanzados del Maule (CIEAM)

Universidad Catolica del Maule

Talca, Chile

2
Inge Wyneken

Full Professor

Medicina

UNIVERSIDAD DE LOS ANDES

Santiago, Chile

2
Pablo Caviedes

Full professor

ICBM

PROGRAMA DE FARMACOLOGÍA MOLECULAR Y CLÍNICA, ICBM, FAC. DE MEDICINA, U. DE CHILE

Santiago, Chile

2
Marc Zeise

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

1
Alejandro Roth

Profesor Asistente

DEPARTAMENTO DE BIOLOGÍA,

DEPARTAMENTO DE BIOLOGÍA, FACULTAD DE CIENCIAS, UNIVERSIDAD DE CHILE

Santiago, Chile

1
María Quintanilla

PROFESOR ASOCIADO

FARMACOLOGÍA MOLECULAR Y CLÍNICA

UNIVERSIDAD DE CHILE, FACULLTAD DE MEDICINA, INSTITUTO DE CIENCIAS BIOMÉDICAS, PROGRAMA DE FARMACOLOGÍA MOLECULAR Y CLÍNICA

Santiago, Chile

1
Claudia Carvallo

Investigadora Principal, Centro de investigación e Innovación en Gerontología Aplicada (CIGAP)

Biología

Universidad Santo Tomás

Santiago, Chile

1
Mario Herrera-Marschitz

Profesor titular

Mol. & Clin. Pharmacology

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA, PROGRAMA FARMACOLOGIA MOLECULAR & CLINICA, ICBM

Santiago, Chile

1
Andrés Couve

Profesor Titular

Neurociencia

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

1
Karen Fuenzalida

Investigador responsable de la Unidad de investigación y desarrollo del Laboratorio de Enfermedades Metabólicas, área de laboratorio.

Instituto de Nutrición y Tecnología de Alimentos

Universidad de Chile

Santiago, Chile

1
Marco Nuñez

Professor

Biology

Fac. Ciencias, Universidad de Chile

Santiago, Chile

1
Carlos Oliva

Profesor Asociado

Biología Celular y Molecular

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Pabla Aguirre

Asistente de investigación

Biología

Universidad de Chile

Santiago, Chile

1
Arnaldo Gatica

Gerente General y fundador

IDEAlim EIRL

San Francisco de Mostazal , Chile

1
Ana Cárdenas

Professor

UNIVERSIDAD DE VALPARAÍSO

Valparaíso, Chile

1
Oliver Schmachtenberg

Investigador titular

Instituto de Biología

Universidad de Valparaíso, CINV

Valparaíso, Chile

1
Luis Barros

Principal Research

Laboratorio Biología Molecular

CENTRO DE ESTUDIOS CIENTÍFICOS

Valdivia, Chile

1
Luis Cid

Principal Research

Laboratorio Biología Molecular

CENTRO DE ESTUDIOS CIENTIFICOS CECs

Valdivia, Chile

1
Patricio Olguín

Assistant Professor

Facultad de Medicina, ICBM, Departamento de Neurociencia

Universidad de Chile

Santiago, Chile

1
Rodolfo Madrid

Full Professor

Departamento de Biología

UNIVERSIDAD DE SANTIGO DE CHILE

Santiago, Chile

1
Marianne Buscaglia

Estudiante de Doctorado en Ciencias Biológicas, mención Genética Molecular y Microbiología

Genética Molecular y Microbiología

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Ramon Jorquera

Assistant Professor

Facultad de Medicina

Universidad Andrés Bello

Santiago, Chile

1
Diego Cosmelli

Profesor Asociado y Sub-director de Investigación y Postgrado

Escuela de Psicología

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

1
Sebastián Loyola

Académico adjunto

Ciencias de la Salud

Universidad Católica Silva Henriquez

Santiago, Chile

1
Cesar Astorga

Postdoctorado

Cs Biomedicas

Universidad Andrés Bello

Santiago, Chile

1
ALEX GALAZ

COFOUNDER (Co-CEO)

INFOOD PROTEIN AND BIOTECHNOLOGY

VALDIVIA, Chile