Canales de cloruro y potasio de epitelios; Estructura -funcion de canales ionicos; Renal and Intestinal physiology and pathophysiology.

Undergraduate Students:

* Juan Pablo Donoso. “Study of interaction of TASK-2 with proteins involved in renal bicarbonate reabsorption: Carbonic Anhydrase II and Sodium Bicarbonate Cotransporter”. Undergraduate Medical Technologist. Universidad Austral de Chile. Finished 2014.
* Karen López C. "Expression of the potassium channel Kir 7.1 and NHE3 sodium proton exchanger in TASK2 KO mice". Undergraduate Biochemist. Universidad Austral de Chile. Finished in 2013.
* Sandra Villanueva S. “Effect of the genetic inactivation of the KCNQ1/KCNE3 potassium channel in the intestinal chloride secretion using murine models”. Undergraduate Biochemist Universidad Austral de Chile. Finished in 2013.
* Alexandra Alvarez A. “Generation of a transgenic mouse expressing a sensor of extracellular in the basolateral membrane of in the renal proximal tubule”. Undergraduate Biochemist Universidad Austral de Chile. Finished in 2011.
* Moisés Sandoval C. Generation of a genetically coded extracellular pH sensor to measure pH in basolateral epithelia microdomains. Undergraduate Biochemist Universidad Austral de Chile. Finished in 2009.
* Andrea Olave E. “Subcellular localization of ClC-2 chloride channel mutants using IFI”. Undergraduate Medical Technologist. Universidad Austral de Chile. Finished in 2009.
* Johanna Burgos V. “Study of the inhibitory mechanism by extracellular acid pH of the chloride channel ClC-Kb”. Undergraduate Biochemist Universidad Austral de Chile. Finished in 2007.
* Carola Maturana F. "Study of the interaction of the SPAK protein kinase with the ClC-2 chloride channel". Undergraduate Biochemist Universidad Austral de Chile. Finished in 2007.
* Gaspar Peña M. "Localization basolateral of the ClC-2 echoride channel in epithelial cell lines". Undergraduate Biochemist Universidad Austral de Chile. Finished 2005.
* Yamil Yusef R. "Effect of an intronic mutation in the function of the ClC-2 choride channel". Undergraduate of the Marine Biology. Universidad Austral de Chile. Finished in 2004.
* Leandro Zúñiga H. "Study of the mechanism of the ClC-2 channel opening by site directed mutagenesis of cysteine 256". Undergraduate Biochemist Universidad Austral de Chile. Finished 2002.
* Isabel Cornejo A. "Cloning and expression of the chloride channel ClC-5 from intestine epithelia of guinea pig".Undergraduate Medical Technologist. Universidad Austral de Chile. Finished in 2000.
* Felipe Estrada A. Generation of knock-in mice with a double lysine mutation in TASK-2 potassium channel using CRISPR-Cas9 technology. Undergraduate Medical Technologist. Universidad Austral de Chile. Ongoing.

Master Student:
Hugo Roa R. "Phenotypic rescue of the KO TASK-2 mouse by expression of the pH sensors mutants of the channel in the renal proximal tubule". Magister in Cellular Biology. Universidad Austral de Chile. Finished 2016.

PhD Student:
* Isabel Cornejo A. "Study of the traffic and membrane surface expression of the ClC-2 chloride channel. Cellular and Molecular Biology PhD. Universidad Austral de Chile. Finished in 2007.

Visit abroad
* Karen Lopez visit the Institut national de la santé et de recherche médicale (Inserm) in Paris and work in the laboratory of Dr. Jacques Teulon, learning the technique of perfusion via the aorta artery, the preparation of samples for the immunofluorescence of kidney, protein quantification and westernblot of renal proteins, 01st May to 01st June 2013.
* Karen Lopez visit the Hôpital Européen Georges-Pompidou in Paris and work in the laboratory of Dr. Dominique Eladari, to perform some analysis of samples, 01st May to 01st June 2013.

Visit in Chile
* Working meetings, Dr. Dominique Eladari and Dra. Regine Chambrey, Université de Paris Decartes Paris, 19th to 31th December 2016.

Collaborative Activities
* Course Program Modules Scholarship Nephrology, "Use of genetically modified animals in the study of physiology and renal disease", Chilean Society of Nephrology, 22- 25 april 2015, Santiago, Chile.
* Course Science and Poetry, "A surprising immune system in bacteria gives us tools to modify complex genomes", Universidad Austral de Chile, 10 May 2016, Valdivia, Chile.

National collaborators
* Leopoldo Ardiles (Universidad Austral de Chile, Valdivia).
* Sandra Bravo (Universidad Austral de Chile, Puerto Montt).
* Marcelo Catalán (Universidad Arturo Prat, Iquique).
* Wendy González (Universidad de Talca, Talca).
* Danilo González-Nilo (Universidad Andrés Bello, Santiago).

International collaborators
* Jacques Teulon and Marc Paulais (Université Pierre at Marie Curie, France),
* Olga Andrini (Université Claude Bernard, France),
* Brian Harvey (Royal College of Surgeons, Dublin Ireland),
* Sarah C. Lummis (University of Cambridge, UK),
* David M. Valenzuela and Venus Lai (Regeneron Pharmaceuticals, NY, USA),
* Dominique Eladari and Régine Chambrey (Université de La Réunion, France.),
* Thomas Jentsch (Leibniz Molecular Pharmacology Institute, Berlin Germany).