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Marcelo Catalan Gaete

Profesor Auxiliar

Universidad Austral de Chile

Valdivia, Chile

Líneas de Investigación


Electrofisiología; Fisiología epitelial; Transporte de iones

Educación

  •  Bioquimica, UNIVERSIDAD DE CHILE. Chile, 1999
  •  Ciencias Biomedicas, UNIVERSIDAD DE CHILE. Chile, 2005

Experiencia Académica

  •   Staff Scientist Full Time

    NATIONAL INSTITUTES OF HEALTH (NIH)

    Estados Unidos

    2010 - 2017

  •   Research Assistant Professor Full Time

    University of Rochester

    Rochester, NY, Estados Unidos

    2009 - 2010

Experiencia Profesional

  •   Staff Scientist Full Time

    National Institutes of Health

    Besthesda, MD, Estados Unidos

    2010 - 2017

  •   Research Assistant Professor Full Time

    University of Rochester

    Rochester, NY, Estados Unidos

    2009 - 2010

  •   Profesor Asociado Full Time

    Universidad Arturo Prat

    Iquique, Chile

    2017 - 2018

  •   Profesor Auxiliar Full Time

    Universidad Austral de Chile

    Valdivia, Chile

    2019 - A la fecha

Premios y Distinciones

  •   Best poster

    11th International Symposium on Exocrine Secretion

    Japón, 2009

    NaCl reabsorption in mouse submandibular gland ductal epithelium requires apical Cftr and ENaC channels.

  •   Nominado a la competencia Hatton

    International Association for Dental Research/Unilever.

    Estados Unidos, 2010

    Enhanced Dental Caries in a Mouse Model of Cystic Fibrosis


 

Article (31)

Short Chain Fatty Acids Effect on Chloride Channel ClC-2 as a Possible Mechanism for Lubiprostone Intestinal Action
Withaferin A suppresses breast cancer cell proliferation by inhibition of the two-pore domain potassium (K2P9) channel TASK-3
Physiological cAMP-elevating secretagogues differentially regulate fluid and protein secretions in mouse submandibular and sublingual glands
A Mathematical Model Supports a Key Role for Ae4 (Slc4a9) in Salivary Gland Secretion
The Insensitivity of TASK-3 K2P Channels to External Tetraethylammonium (TEA) Partially Depends on the Cap Structure
Late responses to adenoviral-mediated transfer of the aquaporin-1 gene for radiation-induced salivary hypofunction
The Role of Na:K:2Cl Cotransporter 1 (NKCC1/SLC12A2) in Dental Epithelium during Enamel Formation in Mice
Ae4 (Slc4a9) is an electroneutral monovalent cation-dependent Cl-/HCO3- exchanger
A fluid secretion pathway unmasked by acinar-specific Tmem16A gene ablation in the adult mouse salivary gland
Ae4 (Slc4a9) Anion Exchanger Drives Cl- Uptake-dependent Fluid Secretion by Mouse Submandibular Gland Acinar Cells
Functional Differences in the Acinar Cells of the Murine Major Salivary Glands
Ca2+-dependent K+ channels in exocrine salivary glands
Association of Bone Morphogenetic Protein 6 With Exocrine Gland Dysfunction in Patients With Sjogren's Syndrome and in Mice
A quantitative analysis of electrolyte exchange in the salivary duct
Severe Defects in Absorptive Ion Transport in Distal Colons of Mice That Lack ClC-2 Channels
Temporal changes in salivary glands of non-obese diabetic mice as a model for Sjogren's syndrome
TRPV4 activation in mouse submandibular gland modulates Ca2+ influx and salivation
Ascl3 knockout and cell ablation models reveal complexity of salivary gland maintenance and regeneration
Elevated Incidence of Dental Caries in a Mouse Model of Cystic Fibrosis
Cftr and ENaC ion channels mediate NaCl absorption in the mouse submandibular gland
Tmem16A Encodes the Ca2+-activated Cl- Channel in Mouse Submandibular Salivary Gland Acinar Cells
Purinergic P2X(7) Receptors Mediate ATP-induced Saliva Secretion by the Mouse Submandibular Gland
A variant of the Ca2+-activated Cl channel Best3 is expressed in mouse exocrine glands
Clcn2 encodes the hyperpolarization-activated chloride channel in the ducts of mouse salivary glands
Removal of gating in voltage-dependent ClC-2 chloride channel by point mutations affecting the pore and C-terminus CBS-2 domain
Basolateral localization of native ClC-2 chloride channels in absorptive intestinal epithelial cells and basolateral sorting encoded by a CBS-2 domain di-leucine motif
Basolateral ClC-2 chloride channels in surface colon epithelium: Regulation by a direct effect of intracellular chloride
The voltage-dependent CIC-2 chloride channel has a dual gating mechanism
A conserved pore-lining glutamate as a voltage- and chloride-dependent gate in the CIC-2 chloride channel
ClC-2 in guinea pig colon: mRNA, immunolabeling, and functional evidence for surface epithelium localization
Nonselective cation channels as effecters of free radical-induced rat liver cell necrosis

Abstract (5)

Exploring the Transport Mechanism of the Human AE4 (SLC4A9) CL-/HCO3- Exchanger
Functional Analysis of the ClC-2 hyperpolarization-activated Cl-channel in Mouse Colon.
Basolateral ClC-2 chloride channels in surface colon epithelium: Regulation by a direct effect of intracellular chloride
Magnesium inhibition of single cardiac RyR channels
Sodium influx through non-selective cation channels: an effector mechanism for necrotic cell death

Proyecto (3)

Ion-transporting pathways in beta-adrenergic receptor stimulated fluid secretion in salivary glands.
Role of the Clcn2 Cl- Channel in Intestinal Fluid Secretion
Proyecto Regular Fondecyt 1171135: Ion-transporting pathways in beta-adrenergic receptor stimulated fluid secretion in salivary glands
36
Marcelo Catalan

Profesor Auxiliar

Facultad de Medicina

Universidad Austral de Chile

Valdivia, Chile

7
Luis Cid

Principal Research

Laboratorio Biología Molecular

CENTRO DE ESTUDIOS CIENTIFICOS CECs

Valdivia, Chile

7
Francisco Sepúlveda

Research

Laboratorio Biología Molecular

CENTRO DE ESTUDIOS CIENTÍFICOS (CECS)

Valdivia, Chile

6
Gaspar Peña

Profesor Asistente

Instituto de Bioquímica y Microbiología

Universidad Austral de Chile

Valdivia, Chile

6
Leandro Zuñiga

Profesor Asociado

Medicine

Universidad de Talca

Talca, Chile

5
Maria Niemeyer

Research

Laboratorio Biología Molecular

CENTRO DE ESTUDIOS CIENTIFICOS CECS

Valdivia, Chile

5
Carlos Figueroa

Head

Anatomy, Histology and Pathology

Universidad Austral de Chile

Valdivia, Chile

2
Andres Stutzin

Full Professor

ICBM

FACULTAD DE MEDICINA UNIVERSIDAD DE CHILE

Santiago, Chile

2
Isabel Cornejo

Investigadora

Biología

Centro de Estudios Científicos

Valdivia, Chile

1
Rafael Zúñiga

Investigador

Facultad de Ingeniería

Universidad de Talca

Talca, Chile

1
Luis Barros

Principal Research

Laboratorio Biología Molecular

CENTRO DE ESTUDIOS CIENTÍFICOS

Valdivia, Chile

1
Diego Varela

Profesor Asociado

Fisiología y Biofísica

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

1
Carlos Flores

Researcher

Biology Lab

CENTRO DE ESTUDIOS CIENTÍFICOS (CECS)

Valdivia, Chile

1
Daniel Bustos

Assistant Professor

Vicerrectoría de Investigación y Postgrado

Universidad Católica del Maule

Talca, Chile