Man

Bárbara Andrea Arévalo Ramos

Investigador

Centro de Estudios de Alimentos Procesados

Talca, Chile

Líneas de Investigación


Proteomics, drug design, modeling and molecular simulation, with knowledge in bioinformatics tools for understanding biological and chemical processes. Specialization in ion channels and characterization of therapeutic targets.

Educación

  •  Ingeniero en bioinformática, UNIVERSIDAD DE TALCA. Chile, 2013
  •  Doctorado en Ciencias mencion investigación y desarrollo de productos bioactivos, UNIVERSIDAD DE TALCA. Chile, 2018

Experiencia Académica

  •   Assistant Part Time

    UNIVERSIDAD DE TALCA

    Ingeniería

    Talca, Chile

    2009 - 2012

  •   Professor Part Time

    Instituto Profesional AIEP

    Ingeniería

    Curico, Chile

    2012 - 2013

  •   Professor Part Time

    UNIVERSIDAD TECNOLOGICA DE CHILE INACAP

    Ingeniería

    Talca, Chile

    2017 - A la fecha

  •   Professor Part Time

    UNIVERSIDAD DE TALCA

    Ingeniería

    Talca, Chile

    2020 - A la fecha

Experiencia Profesional

  •   Practice Full Time

    Fundación de Ciencia para la Vida

    Santiago, Chile

    2011 - 2011

  •   Practice Full Time

    Centro de Bioinfomática y simulación molecular, Universidad de Talca

    Talca, Chile

    2011 - 2011

  •   Thesis student Full Time

    Project Fondecyt Código: 11100373

    Talca, Chile

    2011 - 2012

  •   Director Part Time

    Project Fondef VIU Código: VIUE140068

    Talca, Chile

    2014 - 2015

  •   Researcher in CORFO project, - CONTRATOS TECNOLOGICOS CONCURSO PORFATOLIOS DE ALTO IMPACTO Full Time

    Universidad de Talca

    Talca, Chile

    2018 - 2019

  •   PostDoctorate in Fondecyt Project N 1191133 Full Time

    Universidad de Taca

    Talca, Chile

    2019 - 2020

  •   Researcher Full Time

    Centro de Estudios de Alimentos Procesados

    Talca, Chile

    2020 - A la fecha


 

Article (10)

Diversity of functional alterations of the ClC‐5 exchanger in the region of the proton glutamate in patients with Dent disease 1
Withaferin A suppresses breast cancer cell proliferation by inhibition of the two-pore domain potassium (K2P9) channel TASK-3
Discovery of Novel TASK-3 Channel Blockers Using a Pharmacophore-Based Virtual Screening
Side Fenestrations Provide an "Anchor" for a Stable Binding of A1899 to the Pore of TASK-1 Potassium Channels
Structure-Based Discovery of Potential Two-Pore-Domain Potassium Channel Task-3 (K(2P)9.1) Modulators
Docking's study of 6-substituted adenosine-5'-n-ethyluronamide analogs as selective agonists at a3 adenosine receptor and selection of compounds for to be synthesized later
Molecular modeling and structural analysis of two-pore domain potassium channels TASK1 interactions with the blocker A1899
Synthesis, molecular docking and design of Tetrahydroquinolines as acetylcholinesterase inhibitors
An Extracellular Ion Pathway Plays a Central Role in the Cooperative Gating of a K-2P K+ Channel by Extracellular pH
Synthesis and Characterization of Tetrahydroquinolines as Acetylcholinesterase Inhibitors.

Proyecto (15)

Multidisciplinary studies on bioactive compounds from the Chilean Phaseolus vulgaris L. landraces and their potential effects in the prevention of non-communicable chronic diseases
Fortalecimiento para la continuidad del Centro de Estudios en Alimentos Procesados
Ingredientes Funcionales y Bioproductos de Boldo
Portafolio de servicio biotecnológico en salud
Structural insights into the mechanism of multi-channel blockers of atrial ion channels
VERTICALCROP=> Diseño, implementación y validación de Prototipo modular de cultivo vertical automatizado y autosustentable para la PyMe y AFC hortícola
Implementación de metodologías de enseñanza para alumnos de informática a través del uso de Robótica Educativa
Síntesis y caracterización de un nuevo compuesto que prolongue la conservación postcosecha.
Caracterización de Blancos Terapéuticos a través de Herramientas Bioinformáticas=> Obtención de un Producto Líder y Oferta en Servicios de Consultoría
Development and functional evaluation of synthetic molecules as TASK-3 potassium channel inhibitors for treatment of solid tumors
Understanding the structural mechanism of selective blockers of pH-gated K2P channels.
CHEMICAL STUDY OF SPECIES OF THE GENUS AZORELLA. BIOLOGICAL ACTIVITY OF ITS METABOLITES
REGULATION OF THE ACTIVITY OF TWO-PORE DOMAIN POTASSIUM CHANNELS BY DIFFERENT FACTORS
SYNTHESIS OF DERIVATIVES QUINOLINE-ISOXAZOLE AS INHIBITORS POTENTIALS OF MICROORGANISMS PHYTOPATHOGENIC
EXTRACELLULAR AND INTRACELLULAR SENSORS IN THE GATING OF TASK-2, A TWO-PORE-DOMAIN POTASSIUM CHANNEL.

Review (1)

Adenosine: Synthetic methods of its derivatives and antitumor activity
15
Bárbara Arévalo

Investigador

Investigación

Centro de Estudios de Alimentos Procesados

Talca, Chile

3
Leandro Zuñiga

Profesor Asociado

Medicine

Universidad de Talca

Talca, Chile

3
David Ramirez

Profesor Asistente

Facultad de Ciencias de la Salud

Universidad Autónoma de Chile

Santiago, Chile

3
Wendy Gonzalez

Director of the Center for Bioinformatics, Simulations and Modeling (CBSM)

Bioinformática

CENTRO DE BIOINFORMÁTICA Y SIMULACIÓN MOLECULAR (CBSM)/ UNIVERSIDAD DE TALCA

Talca, Chile

2
Francisco Sepúlveda

Research

Laboratorio Biología Molecular

CENTRO DE ESTUDIOS CIENTÍFICOS (CECS)

Valdivia, Chile

2
Julio Caballero

Full Professor

Departamento de Bioinformática

Universidad de Talca

Talca, Chile

1
margarita gutierrez

Proffesor

UNIVERSIDAD DE TALCA

Talca, Chile

1
Luis Cid

Principal Research

Laboratorio Biología Molecular

CENTRO DE ESTUDIOS CIENTIFICOS CECs

Valdivia, Chile

1
Maria Niemeyer

Research

Laboratorio Biología Molecular

CENTRO DE ESTUDIOS CIENTIFICOS CECS

Valdivia, Chile

1
Miguel Reyes

Full Professor

Facultad de Ciencias Médicas

UNIVERSIDAD DE SANTIAGO DE CHILE, FACULTAD DE CIENCIAS MÉDICAS, ESCUELA DE MEDICINA

Santiago, Chile

1
Nelson Brown

Associate Professor

University of Talca

Talca, Chile

1
Marcelo Catalan

Profesor Auxiliar

Facultad de Medicina

Universidad Austral de Chile

Valdivia, Chile