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Mauricio Bedoya Tabares

Profesor Auxiliar

Universidad Católica del Maule

Talca, Chile

Química computacional aplicada al estudio de canales iónicos y al diseño racional de fármacos.

Pharmaceutical Chemistry, UNIVERSIDAD DE ANTIOQUIA. Colombia, 2015
PhD in Applied Sciences, UNIVERSIDAD DE TALCA. Chile, 2020

Profesor Auxiliar Full Time

UNIVERSIDAD CATOLICA DEL MAULE

CIEAM

Talca, Chile

2022 - A la fecha

Químico Farmacéutico Full Time

Proinsalud S.A

Pasto, Colombia

2015 - 2016


Computational Estimation of Residence Time on Roniciclib and Its Derivatives against CDK2: Extending the Use of Classical and Enhanced Molecular Dynamics Simulations Bravo-Moraga, Felipe; Bedoya, Mauricio; Zinovjev, Kirill; Tunon, Inaki; Alzate-Morales, Jans Article ISI ACS OMEGA (2025)
Main methods and tools for peptide development based on protein-protein interactions (PPIs) Baeza, Javiera; Bedoya, Mauricio; Cruz, Pablo; Ojeda, Paola; Adasme-Carreno, Francisco; Cerda, Oscar; Gonzalez, Wendy Article ISI BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2025)
Rational design, synthesis, and evaluation of novel polypharmacological compounds targeting NaV1.5, KV1.5, and K2P channels for atrial fibrillation Camargo-Ayala, Lorena; Bedoya, Mauricio; Dasi, Albert; Prueser, Merten; Schuette, Sven; Prent-Penaloza, Luis; Adasme-Carreno, Francisco; Kiper, Aytug K.; Rinne, Susanne; Camargo-Ayala, Paola Andrea; et al. Article ISI JOURNAL OF BIOLOGICAL CHEMISTRY (2025)
Crystal structure, quantum chemical insights, and molecular docking studies of Naryl-2-(N-disubstituted) acetamide compounds: potential inhibitors for neurodegenerative enzymes Osorio, Edison Article ISI RSC ADVANCES (2024)
Ion occupancy of the selectivity filter controls opening of a cytoplasmic gate in the K2P channel TALK-2 Neelsen, Lea C.; Riel, Elena B.; Rinne, Susanne; Schmid, Freya-Rebecca; Juers, Bjoern C.; Bedoya, Mauricio; Langer, Jan P.; Eymsh, Bisher; Kiper, Aytug K.; Cordeiro, Soenke; et al. Article ISI NATURE COMMUNICATIONS (2024)
Understanding the Differences of Danusertib's Residence Time in Aurora Kinases A/B: Dissociation Paths and Key Residues Identified using Conventional and Enhanced Molecular Dynamics Simulations Bravo-Moraga, Felipe; Bedoya, Mauricio; Vergara-Jaque, Ariela; Alzate-Morales, Jans Article ISI JOURNAL OF CHEMICAL INFORMATION AND MODELING (2024)
Iridoid esters from<i> Valeriana</i><i> pavonii</i> Poepp. & Endl. as GABAA modulators: Structural insights in their binding mode and structure-activity relationship Giraldo, Sara E.; Bazzocchi, Isabel L.; Marder, Mariel; Vergel, Nadezdha E.; Guerrero, Mario F. Article ISI JOURNAL OF PHARMACY & PHARMACOGNOSY RESEARCH (2023)
Selective TASK-1 Inhibitor with a Defined Structure-Activity Relationship Reduces Cancer Cell Proliferation and Viability Vergara, Fernando; Mazola, Yuliet; Bustos, Daniel; Cikutovic, Rocio; Teresa Ramirez-Apan, M.; Cerda, Oscar; Lopez-Collazo, Eduardo Article ISI JOURNAL OF MEDICINAL CHEMISTRY (2022)
Identification of a critical binding site for local anaesthetics in the side pockets of K(v)1 channels Stalke, Sarah; Marzian, Stefanie; de la Cruz, Alicia; Peraza, Diego A.; Vera-Zambrano, Alba; Marquez Montesinos, Jose C. E.; Arevalo Ramos, Barbara A. Article ISI BRITISH JOURNAL OF PHARMACOLOGY (2021)
Identification of a critical binding site for local anaesthetics in the side pockets of Kv1 channels Kiper, Aytug K.; Bedoya, Mauricio; Stalke, Sarah; Marzian, Stefanie; Ramirez, David; de la Cruz, Alicia; Peraza, Diego A.; Vera-Zambrano, Alba; Marquez Montesinos, Jose C. E.; Arevalo Ramos, Barbara A.; et al. Article WOS BRITISH JOURNAL OF PHARMACOLOGY (2021)
Molecular Pharmacology of K2P Potassium Channels Article CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2021)
Elucidating the Structural Basis of the Intracellular pH Sensing Mechanism of TASK-2 K2P Channels Bustos, Daniel Article ISI SCOPUS INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Identification of the A293 (AVE1231) Binding Site in the Cardiac Two-PoreDomain Potassium Channel TASK-1: a Common Low Affinity Antiarrhythmic Drug Binding Site Wiedmann F, Kiper AK, Bedoya M, Ratte A, Rinné S, Kraft M, Waibel M, Anad P, Wenzel W, González W, Katus HA, Decher N, Schmidt C Article SCOPUS Cellular Physiology and Biochemistry (2019)
Structure/Activity Analysis of TASK-3 Channel Antagonists Based on a 5,6,7,8 tetrahydropyrido[4,3-d]pyrimidine Article ISI SCOPUS INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
TASK Channels Pharmacology: New Challenges in Drug Design Article ISI SCOPUS JOURNAL OF MEDICINAL CHEMISTRY (2019)
The molecular basis for an allosteric inhibition of K+-flux gating in K-2P channels Rinne, S; Kiper, AK; Bedoya, M; Aser, D; Gensler, I; Netter, MF; Stansfeld, PJ; Decher, N Article ISI SCOPUS ELIFE (2019)
A NEW ENHANCED SORBITOL: CALCIUM DIPHOSPHATE COMPOSITE AS A DIRECT COMPRESSION EXCIPIENT: A COMPARATIVE STUDY Echeverri, Edward; Rojas, Jhon Article INTERNATIONAL JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES (2016)


Current Trends in the Production of Cellulose Nanoparticles and Nanocomposites for Biomedical Applications Rojas, John; Ciro, Yhors; Ornaghi Jr., Heitor Luiz BookSection (2015)

1

margarita gutierrez

Proffesor

UNIVERSIDAD DE TALCA

Talca, Chile

5

Wendy Gonzalez

Director of the Center for Bioinformatics, Simulations and Modeling (CBSM)

Bioinformática

CENTRO DE BIOINFORMÁTICA Y SIMULACIÓN MOLECULAR (CBSM)/ UNIVERSIDAD DE TALCA

Talca, Chile

1

Oscar Cerda

Associate Professor

Molecular and Cellular Biology

Universidad de Chile

Santiago, Chile

2

Leandro Zuñiga

Profesor Asociado

Medicine

Universidad de Talca

Talca, Chile

1

Paola Ojeda

Profesora Asociada

Salud

Universidad de Los Lagos

Osorno, Chile

2

Francisco Adasme

Académico Investigador

Universidad Católica del Maule

Talca, Chile

6

David Ramirez

Profesor Asistente

Facultad de Ciencias Biológicas

Universidad de Concepción

Concepcion, Chile

1

Paula Santana

Profesora Asistente e Investigadora

Facultad de Ingeniería

Universidad Autónoma de Chile

Santiago, Chile

1

Samuel Morales

Académico Conferenciante

Universidad de Talca

Talca, Chile

2

Bárbara Arévalo

Investigador

Investigación

Centro de Estudios de Alimentos Procesados

Talca, Chile

4

Daniel Bustos

Auxiliar Professor

Vicerrectoría de Investigación y Postgrado

Universidad Católica del Maule

Talca, Chile

2

Erix Hernández

Full Professor/Departamento de Medicina Traslacional, Académico-Investigador

Departamento de Medicina Traslacional

Universidad Católica del Maule

Talca, Chile

18

Mauricio Bedoya

Profesor Auxiliar

VRIP

Universidad Católica del Maule

Talca, Chile

1

Efrain Polo

Docente

Química Orgánica

Universidad de Concepción

Concepcion, Chile

1

Angel Cayo

ACADÉMICO INVESTIGADOR

MEDICINA TRASLACIONAL

Universidad Católica del Maule

TALCA, Chile