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Mario Martín Chiong Lay

Profesor

Universidad de Chile

Santiago, Chile

- Metabolism in cardiovascular system and disease - Signal transduction in cardiovascular system - Cell death mechanisms

Doctor en Farmacología, Universidad de Chile. Chile, 2009
Bioquímico, Universidad de Chile. Chile, 1986
Licenciado en Bioquímica, Universidad de Chile. Chile, 1986

Profesor Asociado Full Time

UNIVERSIDAD DE CHILE

Facultad de Ciencias Químicas y Farmacéuticas

Santiago, Chile

2010 - 2023
Ayudante Full Time

UNIVERSIDAD DE CHILE

Facultad de Ciencias Químicas y Farmacéuticas

Chile

1988 - 1991
Profesor Asistente Full Time

UNIVERSIDAD DE CHILE

Facultad de Ciencias Químicas y Farmacéuticas

Santiago, Chile

1991 - 1993
Profesor Titular Full Time

UNIVERSIDAD DE CHILE

Facultad de Ciencias Químicas y Farmacéuticas

Santiago, Chile

2023 - A la fecha

Associate Professor Full Time

Unversidad de Chile

Santiago, Chile

2010 - 2023
Full Professor Full Time

Universidad de Chile

Santiago, Chile

2023 - A la fecha

POST-DOCTORAL FELLOWS (University of Chile)
A total of 2 completed (Raúl Vivar, Jaime Riquelme) and 2 ongoing (Valeria Garrido, Francisca Troncoso).

Ph.D. and POST-GRADUATE STUDENTS
Director or Co-director of 9 completed (Gloria Torres; Marina García, David Mondaca, Ignacio Norambuena, Andrea Ramirez, Paulina Villar, Emanuel Guajardo, Fernanda Sanhueza) and 3 ongoing (Esteban Quezada, Raúl Flores, Andrea mella) PhD theses
Director or Co-director of 7 completed (Pablo E. Morales, Tomas Gutierrez; Natalia Venegas, Melany Ríos, Carla Muñoz, Fernanda Sanhueza, Nicole Cancino) and 1 ongoing MSc theses (Francisca Valenzuela)

POST-GRADUATE LECTURE COURSES (Chile)
Lecturer in 5 transversal post-graduate courses of the University of Chile (Basic Concepts in Cell Signalling; Cell Signalling in Biomedicine; Advanced Cell and Molecular Biology Course, Cell Biology and Clinical Pharmacology) per year.

UNDERGRADUATE STUDENT TRAINING IN THE LAB
Director or Co-director of 16 completed and 1 ongoing (Tamara Gonzalez) undergraduate theses

UNDERGRADUATE TEACHING
Coordinator and lecturer in 4 undergraduate teaching (General Physiology; Physiological and Pathological Chemistry course I; Physiological and Pathological Chemistry course II; Physiological and Pathological Chemistry advance course) every year.

PATENTES DE INVENCIÓN

1. Ocaranza MP, Lavandero S, Jalil J, Michea L, Chiong M. Uso de una composición farmacéutica que contiene angiotensina-(1-9) o sus derivados, composición farmacéutica que contiene un vector que expresa la enzima ECA2 que produce angiotensina-(1-9) para elaborar medicamentos útiles para prevenir, revertir, inhibir y/o disminuir la hipertensión arterial y/o inducir vasodilatación. Prioridad CL 950-2010. Presentada en Chile, Oficina de Patentes, Ministerio de Economía Fomento y Reconstrucción. Solicitud internacional PCT/CL2012/000016. Concedida en Estados Unidos US9,511,120 (6 Diciembre 2016).

2. Ocaranza MP, Lavandero S, Jalil J, Chiong M. “Composición farmacéutica que contiene angiotensina-(1-9) o sus derivados, composición farmacéutica que contiene un vector que expresa la enzima ECA2 que produce angiotensina (1 9), usos de dichas composiciones farmacéuticas y del péptido angiotensina-(1-9) para elaborar medicamentos útiles para prevenir, revertir, inhibir y/o disminuir el remodelado cardiovascular, pulmonar, cerebral y/o renal”. Prioridad CL 3736-2008. Presentada en Chile, Oficina de Patentes, Ministerio de Economía Fomento y Reconstrucción. Presentación internacional PCT/CL2009/000029. Concedida en Estados Unidos US9132164 (15 Septiembre 2015) y en Europa EP2377544 (22 Octubre 2015).

3. Sclabos D, Toro R, Chiong M. “Solvent-free process for obtaining phospholipids and neutral enriched krill oils”. Prioridad PCT/IB2009/007269. Presentada en Patent Cooperation Treaty (PCT). Concedida en Estados Unidos US9011942 (21 Abril 2015), US9150815 (6 Octubre 2015), US8865236 (21 Octubre 2014), US8772516 (8 Julio 2014), y US8609157 (17 Diciembre 2013); Japón JP5735521 (17 Junio 2015); China CN102638998 (7 Octubre 2015) y Australia AU2009354456 (8 Mayo 2014).

Premio "Mejor Docente"

UNIVERSIDAD DE CHILE

Chile, 2010

Award gave by the Biochemist students
Premio "Mejor Docente"

UNIVERSIDAD DE CHILE

Chile, 2008

Award gave by the Biochemist students
Scholarship “The British Council”,

BRITISH COUNCIL

Chile, 1990

For a training in the National Institute for Biological Standards and Control in the UK
Scholarship "Beca Presidente de la República"

MINISTERIO DE EDUCACION

Chile, 1981

Scholarshio to study Biochemistry
Colegio de Químicos Farmacéuticos Award

COLEGIO DE QUIMICO FARMACEUTICO DE CHILE A.G.

Chile, 1986

Best student of Biochemstry, promotion 1986
Premio "Mejor Docente"

UNIVERSIDAD DE CHILE

Chile, 2011

Award gave by the Biochemist students
Premio "Mejor Docente"

UNIVERSIDAD DE CHILE

Chile, 2012

Award gave by the Biochemist students
Premio "Mejor Docente"

UNIVERSIDAD DE CHILE

Chile, 2014

Award gave by the Biochemist students
Mejor Docente de Pregrado de la Universidad de Chile 2014

UNIVERSIDAD DE CHILE

Chile, 2014

Award gave by the "Vicerrectoría de Asuntos Estudiantiles, Universidad de Chile"
Premio "Mejor Docente"

UNIVERSIDAD DE CHILE

Chile, 2016

Award gave by the Biochemist students


A potential role of autophagy-mediated vascular senescence in the pathophysiology of HFpEF Martinez-Bilbao, Javiera; Riquelme, Jaime A.; Villa, Monica; Chiong, Mario Article ISI FRONTIERS IN ENDOCRINOLOGY (2023)
Activation of Phosphodiesterase 3A: New Hope for Cardioprotection Chiong, Mario; Westenbrink BD Article ISI CIRCULATION (2023)
Effects of Trimetazidine on Right Ventricular Function and Ventricular Remodeling in Patients with Pulmonary Artery Hypertension: A Randomised Controlled Trial Baraona, Fernando; Chiong, Mario Article ISI JOURNAL OF CLINICAL MEDICINE (2023)
IGF-1 boosts mitochondrial function by a Ca2+ uptake-dependent mechanism in cultured human and rat cardiomyocytes Penannen C; Bomer N; Hoes MF; Van Der Meer P; Chiong, Mario; Westenbrink BD Article ISI FRONTIERS IN PHYSIOLOGY (2023)
Myristate induces mitochondrial fragmentation and cardiomyocyte hypertrophy through mitochondrial E3 ubiquitin ligase MUL1 Westermeier, Francisco; Chiong, Mario Article ISI FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2023)
Targeting VCAM-1: a therapeutic opportunity for vascular damage Riquelme, Jaime A.; Muller, Marioly; Garrido, Luis; Chiong, Mario; Corbalan, Ramon Luis Article ISI EXPERT OPINION ON THERAPEUTIC TARGETS (2023)
Angiotensin-(1-9) in hypertension Hernandez-Fuentes, Carolina Article ISI BIOCHEMICAL PHARMACOLOGY (2022)
Estrogen signaling as a bridge between the nucleus and mitochondria in cardiovascular diseases Chiong, Mario Article ISI FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2022)
Exercise regulation of hepatic lipid droplet metabolism Carlos Borquez, Juan; Chiong, Mario; Troncoso, Rodrigo Article ISI LIFE SCIENCES (2022)
Mitochondrial E3 ubiquitin ligase 1 (MUL1) as a novel therapeutic target for diseases associated with mitochondrial dysfunction Peñaloza-Otárola, A; Troncossi, Angelo; Chiong, Mario Article ISI IUBMB LIFE (2022)
Mitophagy in cardiovascular diseases: molecular mechanisms, pathogenesis, and treatment Ajoolabady A; Chiong, Mario Article ISI TRENDS IN MOLECULAR MEDICINE (2022)
Regulation of total LC3 levels by angiotensin II in vascular smooth muscle cells Quiroga, Clara; Riquelme, Jaime A.; Bustamante, Mario; Chiong, Mario Article ISI JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2022)
The role of autophagy in cardiovascular pathology Chiong, Mario Article ISI CARDIOVASCULAR RESEARCH (2022)
Circulating Vascular Cell Adhesion Molecule-1 (sVCAM-1) Is Associated With Left Atrial Remodeling in Long-Distance Runners Vega-Adauy, Julian; Jalil, Jorge E.; Garcia, Lorena; Chiong, Mario Article ISI FRONTIERS IN CARDIOVASCULAR MEDICINE (2021)
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) Abdel-Aziz, Amal Kamal; Abdelfatah, Sara; Abdellatif, Mahmoud; Abdoli, Asghar; Abel, Steffen; Abildgaard, Marie H.; Abudu, Yakubu Princely; Acevedo-Arozena, Abraham; Adamopoulos, Iannis E.; Adolph, Timon E.; et al. Article ISI AUTOPHAGY (2021)
Impact of the Potential Antitumor Agent 2-(4-Hydroxyphenyl) Amino-1,4-Naphthoquinone (Q7) on Vasomotion Is Mediated by the Vascular Endothelium, But Not Vascular Smooth Muscle Cell Metabolism Palacios, Javier; Chiong, Mario; Paredes, Adrian; Cifuentes, Fredi Article ISI JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2021)
Left Cardiac Remodelling Assessed by Echocardiography Is Associated with Rho-Kinase Activation in Long-Distance Runners Fernandez, Rodrigo; Jalil, Jorge E.; Chiong, Mario; Godoy, Paz Article ISI JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE (2021)
Novel Insights Into the Pathogenesis of Diabetic Cardiomyopathy and Pharmacological Strategies Chiong, Mario Article ISI FRONTIERS IN CARDIOVASCULAR MEDICINE (2021)
Polycystin-1 is required for insulin-like growth factor 1-induced cardiomyocyte hypertrophy Fernandez, Carolina; Torrealba, Natalia; Altamirano, Francisco; Flores-Vergara, Raul; Chiong, Mario Article ISI PLOS ONE (2021)
Polycystin-1 regulates cardiomyocyte mitophagy Quiroga, Clara; Hendrickson, Troy; Altamirano, Francisco; Chiong, Mario Article ISI FASEB JOURNAL (2021)
Role of Interleukin-6 in Vascular Health and Disease Hernandez-Vargas, Felipe; Troncoso, Rodrigo; Chiong, Mario Article ISI FRONTIERS IN MOLECULAR BIOSCIENCES (2021)
Soluble Interleukin-6 Receptor Regulates Interleukin-6-Dependent Vascular Remodeling in Long-Distance Runners Hernandez-Diaz, Tomas; Mandiola, Jorge; Bruneau, Nicole; Garcia, Lorena; Troncoso, Rodrigo; Chiong, Mario Article ISI FRONTIERS IN PHYSIOLOGY (2021)
VCAM-1 as a predictor biomarker in cardiovascular disease Chiong, Mario; Garcia, Lorena Article ISI BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2021)
Angiotensin-(1-7) Prevents Lipopolysaccharide-Induced Autophagy via the Mas Receptor in Skeletal Muscle Rivera, Juan Carlos; Abrigo, Johanna; Simon, Felipe; Santos, Robson A.; Bader, Michael; Chiong, Mario Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Angiotensin-(1-9) prevents vascular remodeling by decreasing vascular smooth muscle cell dedifferentiation through a FoxO1-dependent mechanism Novoa, Ulises; Jalil, Jorge E.; Chiong, Mario Article ISI BIOCHEMICAL PHARMACOLOGY (2020)
beta-Hydroxybutyrate Increases Exercise Capacity Associated with Changes in Mitochondrial Function in Skeletal Muscle Morales, Pablo Esteban; Sepulveda, Carlos; Chiong, Mario; Eisner, Veronica; Troncoso, Rodrigo Article ISI NUTRIENTS (2020)
Light-induced release of the cardioprotective peptide angiotensin-(1-9) from thermosensitive liposomes with gold nanoclusters Ramirez-Sagredo, Andrea; Riveros, Ana L.; Riquelme, Jaime A.; Araya, Eyleen; Chiong, Mario; Villamizar Sarmiento, Maria Gabriela Article ISI JOURNAL OF CONTROLLED RELEASE (2020)
Moderate Aerobic Exercise Training Prevents the Augmented Hepatic Glucocorticoid Response Induced by High-Fat Diet in Mice Dassonvalle, Jonatan; Sepulveda, Carlos; Pino, Pamela; Chiong, Mario; Llanos, Miguel; Troncoso, Rodrigo Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Preoperative solubleVCAM-1 contributes to predict late mortality after coronary artery surgery Garcia, Mauricio; Garcia, Lorena; Mellado, Rosemarie; Zalaquett, Ricardo; Chiong, Mario; Quitral, Jorge Article ISI CLINICAL CARDIOLOGY (2020)
Angiotensin II-Regulated Autophagy Is Required for Vascular Smooth Muscle Cell Hypertrophy Mondaca-Ruff, D; Riquelme, JA; Quiroga, C; Norambuena-Soto, I; Sanhueza-Olivares, F; Villar-Fincheira, P; Hernandez-Diaz, T; Cancino-Arenas, N; Martin, AS; Garcia, L; Lavandero, S; Chiong, M Article FRONTIERS IN PHARMACOLOGY (2019)
Evaluation of computer-based retinopathy of prematurity (ROP) education for ophthalmology residents: a randomized, controlled, multicenter study Roohipoor R.; Brodowska K.; Kloek C.; Riazi M.; Nourinia R.; Nikkhah H.; Prajna N.V.; Krishnan C.; Tuli S.; Green L.; et al. Article ISI SCOPUS JOURNAL OF AAPOS (2019)
Exercise regulates lipid droplet dynamics in normal and fatty liver Pino-de la Fuente, Francisco; Sepulveda, Carlos; Chiong, Mario; Llanos, Miguel; Troncoso, Rodrigo Article ISI SCOPUS BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2019)
Polyphenolic Composition and Hypotensive Effects of Parastrephia quadrangularis (Meyen) Cabrera in Rat Cifuentes, Fredi; Palacios, Javier; Borquez, Jorge; Simirgiotis, Mario J; Chiong, Mario; Paredes, Adrian Article ISI SCOPUS ANTIOXIDANTS (2019)
Angiotensin-(1-9) reduces cardiovascular and renal inflammation in experimental renin-independent hypertension Gonzalez L., Novoa U.; Moya J., Gabrielli L.; Jalil J.E., GarcÃa L.; Chiong M., Lavandero S. Article Biochemical Pharmacology (2018)
Autophagy and oxidative stress in non-communicable diseases: A matter of the inflammatory state? Diaz-Vega, Alexis; Chiong, Mario; Garcia, Lorena; Bambs, Claudia; Troncoso, Rodrigo; Cifuentes, Mariana; Ferreccio, Catterina; Quest, Andrew F G; Criollo, Alfredo Article ISI SCOPUS FREE RADICAL BIOLOGY AND MEDICINE (2018)
Autophagy mediates tumor necrosis factor-alpha-induced phenotype switching in vascular smooth muscle A7r5 cell line Garcia-Miguel, M; Riquelme, JA; Norambuena-Soto, I; Morales, PE; Sanhueza-Olivares, F; Nunez-Soto, C; Mondaca-Ruff, D; Cancino-Arenas, N; San Martin, A; Chiong, M Article PLOS ONE (2018)
Herpudl impacts insulin-dependent glucose uptake in skeletal muscle cells by controlling the Ca2+-calcineurin-Akt axis Navarro-Marquez, M; Torrealba, N; Troncoso, R; Vasquez-Trincado, C; Rodriguez, M; Morales, PE; Villalobos, E; Eura, Y; Garcia, L; Chiong, M; Klip, A; Jaimovich, E; Kokame, K; Lavandero, S Article BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2018)
Increased active phase atrial contraction is related to marathon runner performance Gabrielli, L; Herrera, S; Contreras-Briceno, F; Vega, J; Ocaranza, MP; Yanez, F; Fernandez, R; Saavedra, R; Sitges, M; Garcia, L; Chiong, M; Lavandero, S; Castro, PF Article EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY (2018)
Mechanical stretch increases L-type calcium channel stability in cardiomyocytes through a polycystin-1/AKT-dependent mechanism Cordova-Casanova, A; Olmedo, I; Riquelme, JA; Barrientos, G; Sanchez, G; Gillette TG, Lavandero; S, Chiong; M, Donoso; P, Pedrozo Article BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2018)
Potential adverse cardiac remodelling in highly trained athletes=> still unknown clinical significance Gabrielli, L; Sitges, M; Chiong, M; Jalil, J; Ocaranza, M; Llevaneras, S; Herrera, S; Fernandez, R; Saavedra, R; Yanez, F; Vergara, L; Diaz, A; Lavandero, S; Castro, P Article EUROPEAN JOURNAL OF SPORT SCIENCE (2018)
The STIM1 inhibitor ML9 disrupts basal autophagy in cardiomyocytes by decreasing lysosome content Shaikh, S.; Troncoso, R.; Mondaca-Ruff, D.; Parra, V; Garcia, L.; Chiong, M.; Lavandero, S. Article Toxicology in Vitro (2018)
Vasodilator and hypotensive effects of pure compounds and hydroalcoholic extract of Xenophyllum poposum (Phil) V.A Funk (Compositae) on rats Cifuentes, Fredi; Palacios, Javier; Kuzmicic, Jovan; Quispe, Cristina; Morales, Glauco; Chiong, Mario; Paredes, Adrian Article ISI SCOPUS PHYTOMEDICINE (2018)
Sarcoplasmic reticulum-mitochondria communication in cardiovascular pathophysiology. Lopez-Crisosto, Camila; Pennanen, Christian; Vasquez-Trincado, Cesar; Morales, Pablo E; Bravo-Sagua, Roberto; Quest, Andrew F G; Chiong, Mario; Lavandero, Sergio Article Nature reviews. Cardiology (2017)
Acute effect of iloprost inhalation on right atrial function and ventricular dyssynchrony in patients with pulmonary artery hypertension Sitges, Marta; Kanacri, Andrés Article ISI SCOPUS ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES (2017)
Herpud1 negatively regulates pathological cardiac hypertrophy by inducing IP3 receptor degradation Torrealba, N; Navarro-Marquez, M; Garrido, V; Pedrozo, Z; Romero, D; Eura, Y; Villalobos, E; Roa, JC; Chiong, M; Kokame, K; Lavandero, S Article Scientific Reports (2017)
Increased C-reactive protein plasma levels are not involved in the onset of post-operative atrial fibrillation Becerra, Elia; Navarro-Marquez, Mario Article ISI SCOPUS JOURNAL OF CARDIOLOGY (2017)
Inhibition of mitochondrial fission prevents hypoxia-induced metabolic shift and cellular proliferation of pulmonary arterial smooth muscle cells Bravo-Sagua, Roberto; Norambuena-Soto, Ignacio; Hernández-Fuentes, Carolina P.; Gómez-Contreras, Andrés G. Article ISI SCOPUS Biochimica et Biophysica Acta - Molecular Basis of Disease (2017)
Sarcoplasmic reticulum-mitochondria communication in cardiovascular pathophysiology Vasquez-Trincado, Cesar; Bravo-Sagua, Roberto Article ISI SCOPUS NATURE REVIEWS CARDIOLOGY (2017)
Transforming growth factor-beta and Forkhead box O transcription factors as cardiac fibroblast regulators Norambuena-Soto, Ignacio; Núñez-Soto, Constanza; Sanhueza-Olivares, Fernanda; Cancino-Arenas, Nicole; Mondaca-Ruff, David Article ISI SCOPUS BIOSCIENCE TRENDS (2017)
Atrial Function Assessed by Speckle Tracking Echocardiography Is a Good Predictor of Postoperative Atrial Fibrillation in Elderly Patients Verdejo, HE; Becerra E.; Zalaquet, R; del Campo, A; Garcia, L.; Troncoso R.; Chiong M.; MarÍn A.; Lavandero S.; Gabrielli, L; et al. Article ISI SCOPUS ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES (2016)
BAG3 regulates total MAP1LC3B protein levels through a translational but not transcriptional mechanism Salas, D.; Parra, V; Quiroga, C; Morawe T.; Chiong M.; Behl C.; Lavandero S. Article ISI SCOPUS AUTOPHAGY (2016)
Basal autophagy protects cardiomyocytes from doxorubicin-induced toxicity Article ISI SCOPUS TOXICOLOGY (2016)
FoxO1 mediates TGF-beta1-dependent cardiac myofibroblast differentiation Vivar, R; Humeres, C.; Munoz, C; Boza P.; Bolivar S.; Tapia, F; Lavandero S.; Chiong M.; Diaz-Araya, G Article ISI SCOPUS BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2016)
Glucagon-like peptide-1 inhibits vascular smooth muscle cell dedifferentiation through mitochondrial dynamics regulation Torres, G; Morales PE; Garcia-Miguel, M; Norambuena-Soto, I; Cartes-Saavedra, B; Vidal-Pena, G; Moncada-Ruff, D; Sanhueza Olivares F; San Martin, A; Chiong M. Article ISI SCOPUS BIOCHEMICAL PHARMACOLOGY (2016)
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) Klionsky, Daniel J; Abdelmohsen, Kotb; Abe, Akihisa; Abedin, Md Joynal; Abeliovich, Hagai; Acevedo Arozena, Abraham; Adachi, Hiroaki; Adams, Christopher M; Adams, Peter D; Adeli, Khosrow; et al. Article SCOPUS AUTOPHAGY (2016)
HERPUD1 protects against oxidative stress-induced apoptosis through downregulation of the inositol 1,4,5-trisphosphate receptor Paredes, F; Parra, V; Torrealba, N; Navarro-Marquez, M; Gatica, D; Bravo Sagua R; Troncoso R.; Pennanen C.; Quiroga, C; Chiong M.; et al. Article ISI SCOPUS FREE RADICAL BIOLOGY AND MEDICINE (2016)
Modulatory Effect of 2-(4-Hydroxyphenyl)amino-1,4-naphthoquinone on Endothelial Vasodilation in Rat Aorta Gonzalez, Constanza; Cartes-Saavedra, Benjamín Article ISI SCOPUS OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)
TonEBP suppresses IL-10-mediated immunomodulation Lee, J. H.; Ye B.J.; Yoo E.J.; Kang H.J.; Jung G.W.; An S.M.; Lee-Kwon W.; Chiong M.; Lavandero S. Article ISI SCOPUS SCIENTIFIC REPORTS (2016)
ACE2 and vasoactive peptides: novel players in cardiovascular/renal remodeling and hypertension. Mendoza-Torres, Evelyn; Oyarzún, Alejandra; Mondaca-Ruff, David; Azocar, Andrés; Castro, Pablo F; Jalil, Jorge E; Chiong, Mario; Lavandero, Sergio; Ocaranza, María Paz Article Therapeutic advances in cardiovascular disease (2015)
Autophagy in cardiovascular biology. Lavandero S, Chiong M, Rothermel BA, Hill JA. Article Journal of Clinical Investigation (2015)
Insulin/NF kappa B protects against ischemia-induced necrotic cardiomyocyte death Diaz A.; Humeres, C.; González V.; Gomez, MT; Montt, N; Sánchez G; Chiong M.; Garcia, L. Article ISI SCOPUS Biochemical and Biophysical Research Communications (2015)
Molecular mechanisms of autophagy in the cardiovascular system Gatica D, Chiong M, Lavandero S, Klionsky DJ. Article CIRCULATION RESEARCH (2015)
Novel players in cardioprotection: Insulin like growth factor-1, angiotensin-(1-7) and angiotensin-(1-9). Westermeier, Francisco; Bustamante, Mario; Pavez, Mario; García, Lorena; Chiong, Mario; Ocaranza, María Paz; Lavandero, Sergio Article Pharmacological research (2015)
Alteration in mitochondrial Ca2+ uptake disrupts insulin signaling in hypertrophic cardiomyocytes Gutiérrez T.; Parra, V; Troncoso R.; Pennanen C.; Contreras-Ferrat, A; Vasquez-Trincado, C; Morales PE; López-Crisosto, C; Sotomayor-Flores, C; Chiong M.; et al. Article ISI SCOPUS CELL COMMUNICATION AND SIGNALING (2014)
Angiotensin-(1-9) reverses experimental hypertension and cardiovascular damage by inhibition of the angiotensin converting enzyme/Ang II axis Ocaranza, Maria Paz; Moya, Jackeline; Barrientos, Victor; Alzamora, Rodrigo; Hevia, Daniel; Morales, Cristobal; Pinto, Melissa; Escudero, Nicolas; Garcia, Lorena; Novoa, Ulises; et al. Article ISI SCOPUS JOURNAL OF HYPERTENSION (2014)
Drp1 Loss-of-function Reduces Cardiomyocyte Oxygen Dependence Protecting the Heart From Ischemia-reperfusion Injury Zepeda R, Kuzmicic J, Parra V, Troncoso R, Pennanen C, Riquelme JA, Pedrozo Z, Chiong M, Sánchez G, Lavandero S. Article ISI SCOPUS JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2014)
Effects of Trimetazidine in Nonischemic Heart Failure: A Randomized Study Winter, José Luis; Castro Pablo F.,; Quintana, Juan Carlos; Altamirano, Rodrigo; Enriquez, Andres; Verdejo Hugo E.; Jalil, Jorge E.; Mellado, Rosemarie; Concepción, Roberto; Sepulveda, Pablo; et al. Article ISI JOURNAL OF CARDIAC FAILURE (2014)
Effects of trimetazidine in nonischemic heart failure: a randomized study. Winter, José Luis; Castro, Pablo F; Quintana, Juan Carlos; Altamirano, Rodrigo; Enriquez, Andres; Verdejo, Hugo E; Jalil, Jorge E; Mellado, Rosemarie; Concepción, Roberto; Sepúlveda, Pablo; Rossel, Victor; Sepúlveda, Luis; Chiong, Mario; García, Lorena; Lavandero, Sergio Article Journal of cardiac failure (2014)
Effects of Trimetazidine in Nonischemic Heart Failure=> A Randomized Study Winter, JL; Castro, PF; Quintana, JC; Altandrano, R; Enriquez, A; Verdejo, HE; Jalil JE, Mellado; R, Concepcion; R, Sepúlveda P.; Rossel, V; Sepulveda, L; Chiong M., García L. Article Journal of Cardiac Failure (2014)
GLP-1 promotes mitochondrial metabolism in vascular smooth muscle cells by enhancing endoplasmic reticulum-mitochondria coupling Morales, Pablo E; Torres, Gloria; Sotomayor-Floresc Cristian; Peña-Oyarzún, Daniel; Rivera-Mejías, Pablo; Paredes, felipe; Chiong, Mario Article ISI SCOPUS BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
Insulin Stimulates Mitochondrial Fusion and Function in Cardiomyocytes via the Akt-mTOR-NF kappa B-Opa-1 Signaling Pathway Parra, V; Verdejo, HE; Iglewski, M; del Campo, A; Troncoso R.; Jones D.; Zhu, Y; Kuzmicic J.; Pennanen C.; López-Crisosto, C; et al. Article ISI SCOPUS DIABETES (2014)
Mitochondrial fission is required for cardiomyocyte hypertrophy mediated by a Ca2+-calcineurin signaling pathway Pennanen, Christian; Parra, Valentina; López-Crisosto, Camila; Morales, Pablo E; del Campo, Andrea; Gutierrez, Tomás; Rivera-Mejías, Pablo; Kuzmicic, Jovan; Chiong, Mario; Zorzano, Antonio; et al. Article ISI SCOPUS JOURNAL OF CELL SCIENCE (2014)
Mitochondrial fragmentation impairs insulin-dependent glucose uptake by modulating Akt activity through mitochondrial Ca2+ uptake del Campo, A; Parra, V; Vasquez-Trincado, C; Gutiérrez T.; Morales PE; López-Crisosto, C; Bravo Sagua R; Verdejo, HE; Contreras-Ferrat, A; Troncoso R.; et al. Article ISI SCOPUS AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2014)
Mitochondrial metabolism and the control of vascular smooth muscle cell proliferation Chiong M, Cartes-Saavedra B, Norambuena-Soto I, Mondaca-Ruff D, Morales PE, García-Miguel M, Mellado R. Article Frontiers in cell and developmental biology (2014)
Organelle communication: signaling crossroads between homeostasis and disease. Bravo-Sagua, Roberto; Torrealba, Natalia; Paredes, Felipe; Morales, Pablo E; Pennanen, Christian; López-Crisosto, Camila; Troncoso, Rodrigo; Criollo, Alfredo; Chiong, Mario; Hill, Joseph A; Simmen, Thomas; Quest, Andrew F; Lavandero, Sergio Article The international journal of biochemistry & cell biology (2014)
Organelle communication=> Signaling crossroads between homeostasis and disease Bravo Sagua R, Torrealba N.; Paredes F., Morales; PE, Pennanen; C, López-Crisosto; C, Troncoso R; Criollo A, Chiong M.; Hill, JA; Simmen T, Quest AF Article The International Journal of Biochemistry & Cell Biology (2014)
Recent insights and therapeutic perspectives of angiotensin-(1-9) in the cardiovascular system. Ocaranza, Maria Paz; Michea, Luis; Chiong, Mario; Lagos, Carlos F; Lavandero, Sergio; Jalil, Jorge E Article Clinical science (London, England : 1979) (2014)
Reply: dissociating angiotensin 1-9 anticardiovascular remodeling effects from those on blood pressure Ocaranza, Maria Paz; Michea, Luis; Chiong, Mario; Lavandero, Sergio; Jalil, Jorge E. Article ISI JOURNAL OF HYPERTENSION (2014)
Role of Heterotrimeric G Protein and Calcium in Cardiomyocyte Hypertrophy Induced by IGF-1 CARRASCO L.; Cea, P; Rocco, P; Pena-Oyarzun, D; Rivera-Mejias, P; Sotomayor-Flores, C; Quiroga, C; Criollo, A; Ibarra, C; Chiong M.; et al. Article ISI SCOPUS JOURNAL OF CELLULAR BIOCHEMISTRY (2014)
Trimetazidine prevents palmitate-induced mitochondrial fission and dysfunction in cultured cardiomyocytes Kuzmicic, Jovan; Parra, Valentina; Verdejo Hugo E.; López-Crisosto, Camila; Chiong, Mario; Garcia, Lorena; Jensen, Michael D.; Bernlohr, David A.; Castro Pablo F.,; Lavandero, Sergio Article ISI SCOPUS BIOCHEMICAL PHARMACOLOGY (2014)
Cell Death and Survival Through the Endoplasmic Reticulum-Mitochondrial Axis Bravo Sagua R; Rodríguez, AE; Kuzmicic J.; Gutiérrez T.; López-Crisosto, C; Quiroga, C; Diaz-Elizondo, J; Chiong M.; Gillette, TG; Rothermel BA; et al. Article ISI CURRENT MOLECULAR MEDICINE (2013)
Endocytic pathway of exogenous iron-loaded ferritin in intestinal epithelial (Caco-2) cells Antileo, E; Garri, C; Tapia, V; Munoz, JP; Chiong M.; Nualart, F.; Lavandero S.; Fernández J Article ISI SCOPUS American Journal of Physiology - Gastrointestinal and Liver Physiology (2013)
Herp depletion protects from protein aggregation by up-regulating autophagy Quiroga, C; Gatica, D; Paredes, F; Bravo, R.; Troncoso R.; pedrozo, Z; Rodríguez, AE; Toro, B; Chiong M.; Hetz C. ; et al. Article ISI SCOPUS Biochimica et Biophysica Acta - Molecular Cell Research (2013)
Influence of glucose metabolism on vascular smooth muscle cell proliferation Chiong, M.; Morales, P.; Torres, G.; Gutiérrez, T.; García, L.; Ibacache, M.; Michea, L. Article VASA (2013)
Local Control of Nuclear Calcium Signaling in Cardiac Myocytes by Perinuclear Microdomains of Sarcolemmal Insulin-Like Growth Factor 1 Receptors Ibarra, C; Estrada, M; Lin, YB; Rocco, P; Rebellato, P; Munoz, JP; Garcia-Prieto, J; Quest, AFG; Chiong M.; Davidson, SM; et al. Article ISI SCOPUS Circulation Research (2013)
Angiotensina-(1-9) disminuye el remodelamiento cardiovascular hipertensivo independiente de los niveles de ECA y de angiotensina II Moya, J.; Novoa, U.; Godoy, I.; Chiong, M.; Lavandero, S.; Jalil, J.; Ocaranza, MP. Article REVISTA CHILENA DE CARDIOLOGIA (2012)
Endoplasmic reticulum: ER stress regulates mitochondrial bioenergetics Bravo, R.; Gutiérrez T.; Paredes, F; Gatica, D; pedrozo, Z; Chiong M.; Parra, V; Rothermel, B. A.; Lavandero S. Article ISI SCOPUS International Journal of Biochemistry and Cell Biology (2012)
Energy-preserving effects of IGF-1 antagonize starvation-induced cardiac autophagy Troncoso R.; Vicencio J.M.; Parra, V; Nemchenko A.; Kawashima Y.; del Campo, A; Toro, B; Aranguiz, P; Chiong M.; Yakar S.; et al. Article ISI SCOPUS CARDIOVASCULAR RESEARCH (2012)
Mayores niveles de ECA y Angiotensina II determinados genéticamente, se asocian a menor actividad del eje ECA2/angiotensina-(1-9) y mayor remodelamiento de la pared aórtica de ratas hipertensas Moya, Jackeline; Novoa, Ulises; Escudero, Nicolas; Godoy, Ivan; Chiong, Mario; Lavandero, Sergio; Jalil, Jorge; Ocaranza, Maria Paz Article SCIELO Revista chilena de cardiologï¿½a (2012)
Relationship between mechanical and metabolic dyssynchrony with left bundle branch block: Evaluation by 18-fluorodeoxyglucose positron emission tomography in patients with non-ischemic heart failure Castro P. ; Verdejo H.; Orellana P.; greig d.; Enriquez A.; Sepulveda, L; Concepcion, R; Sepulveda P.; Rossel V.; Chiong M.; et al. Article ISI SCOPUS Journal of Heart and Lung Transplantation (2012)
Simvastatin disrupts cytoskeleton and decreases cardiac fibroblast adhesion, migration and viability Copaja M; Venegas, D; Aranguiz, P; Canales, J; Vivar, R; Avalos, Y; Garcia, L.; Chiong M.; Olmedo, I; Catalán M.; et al. Article ISI SCOPUS Toxicology (2012)
Autophagy as a therapeutic target in cardiovascular disease Nemchenko, A.; Chiong, M.; Turer, A.; Lavandero, S.; Hill, JA. Article JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2011)
Cardiomyocyte death: mechanisms and translational implications Chiong, M.; Wang, ZV.; Pedrozo, Z.; Cao, DJ.; Troncoso, R.; Ibacache, M.; Criollo, A.; Nemchenko, A.; Hill, JA.; Lavandero, S. Article CELL DEATH & DISEASE (2011)
Increased ER-mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress Bravo, R.; Parra, V; Troncoso R.; Munoz, JP; Bui, M; Quiroga, C; Rodríguez, AE; Verdejo, HE; Ferreira J.; Iglewski, M; et al. Article ISI SCOPUS Journal of Cell Science (2011)
Inhibition of Cyclin-Dependent Kinase 5 but Not of Glycogen Synthase Kinase 3-beta Prevents Neurite Retraction and Tau Hyperphosphorylation Caused by Secretable Products of Human T-Cell Leukemia Virus Type I-Infected Lymphocytes Maldonado, H.; Ramirez E; Utreras, E; Pando, ME; Chiong M.; Collados, L; Puente J.; Cartier, L; Valenzuela, MA. Article ISI SCOPUS Journal of Neuroscience Research (2011)
Markedly increased Rho-kinase activity in circulating leukocytes in patients with chronic heart failure Gabrielli, L; Mora I; Garcia, L.; Godoy, I.; Braun, S; Cordova, S; Castro P. ; Novoa U.; Chiong M.; Lavandero S. Article ISI SCOPUS American Heart Journal (2011)
Mitochondrial dynamics: a potential new therapeutic target for heart failure Kuzmicic, J.; Del Campo, A.; López-Crisosto, C.; Morales, PE.; Pennanen, C.; Bravo-Sagua, R.; Hechenleitner, J.; Zepeda, R.; Castro, PF.; Verdejo, HE.; Parra, V.; Chiong, M.; Lavandero, S. Article Rev Esp Cardiol (2011)
Rho kinase inhibition activates the homologous angiotensin-converting enzyme-angiotensin-(1-9) axis in experimental hypertension rivera, p; Novoa U.; Pinto, M; González L.; Chiong M.; Lavandero S. Article ISI SCOPUS Journal of Hypertension (2011)
Simvastatin induces apoptosis by a Rho-dependent mechanism in cultured cardiac fibroblasts and myofibroblasts Copaja M; Venegas, D; Aranguiz, P; Canales, J; Vivar, R; Catalán M.; Olmedo, I; Rodríguez, AE; Chiong M.; Leyton, L.; et al. Article ISI SCOPUS Toxicology and Applied Pharmacology (2011)
Systemic Oxidative Stress and Endothelial Dysfunction is Associated With an Attenuated Acute Vascular Response to Inhaled Prostanoid in Pulmonary Artery Hypertension Patients Gabrielli, LA; Godoy, I.; Mellado R.; Bourge, RC; Alcaino H; Chiong M.; greig d.; Verdejo, HE; Navarro M.; Lòpez, R; et al. Article ISI SCOPUS Journal of Cardiac Failure (2011)
Systemic vascular cell adhesion molecule-1 predicts the occurrence of post-operative atrial fibrillation Verdejo H.; Roldan, J; Garcia, L.; del Campo, A; Becerra E.; Chiong M.; Mellado R.; Garcia, A.; Zalaquett R.; Braun, S; et al. Article ISI SCOPUS INTERNATIONAL JOURNAL OF CARDIOLOGY (2011)
The role of uric acid in heart failure Alcaino H; greig d.; Castro P. ; Verdejo H.; Mellado R.; Garcia, L.; Diaz-Araya, G; Quiroga, C; Chiong M.; Lavandero S. Article ISI REVISTA MEDICA DE CHILE (2011)
Xanthine-oxidase inhibitors and statins in chronic heart failure: Effects on vascular and functional parameters greig d.; Alcaino H; Garcia, L.; Verdejo, HE; Navarro M.; Lòpez, R; Mellado R.; Tapia, F; Gabrielli, LA; Nogerol C.; et al. Article ISI SCOPUS Journal of Heart and Lung Transplantation (2011)
An Inositol 1,4,5-Triphosphate (IP3)-IP3 Receptor Pathway Is Required for Insulin-Stimulated Glucose Transporter 4 Translocation and Glucose Uptake in Cardiomyocytes Contreras-Ferrat, AE; Toro, B; Bravo, R.; Parra, V; Vasquez, C.; Ibarra, C; Mears, D; Chiong M.; Jaimovich E.; Klip, A; et al. Article ISI SCOPUS Endocrinology (2010)
Angiotensin-(1-9) regulates cardiac hypertrophy in vivo and in vitro Lavandero S.; Moya, J; Pinto, M; Novoa U.; Apablaza F.; González L.; Hernandez C.; Varas, M; Lòpez, R; Godoy, I.; et al. Article ISI SCOPUS Journal of Hypertension (2010)
Determinaciones de niveles de creatina y lípidos mediante espectroscopia por resonancia magnética en miocardio de pacientes con insuficiencia cardiaca no isquémica Winter, José Luis; Castro, Pablo; Meneses, Luis; CHALHUB, MÓNICA; Verdejo, Hugo; Greig, Douglas; Gabrielli, Luigi; Chiong, Mario; Concepción, Roberto; MELLADO, ROSEMERIE; et al. Article SCIELO REVISTA MEDICA DE CHILE (2010)
Glucose deprivation causes oxidative stress and stimulates aggresome formation and autophagy in cultured cardiac myocytes Marambio P.; Toro, B; Sanhueza C.; Troncoso R.; Parra, V; Verdejo H.; Garcia, L.; Quiroga, C; Munafo, D; Diaz-Elizondo, J; et al. Article ISI SCOPUS Biochimica et Biophysica Acta - Molecular Basis of Disease (2010)
Heart energy metabolism and its role in the treatment of heart failure Metabolismo energético del corazón y sus proyecciones en el tratamiento de la insuficiencia cardíaca Castro P. ; Gabrielli, L; Verdejo H.; greig d.; Llevaneras, S; Hernandez C.; Godoy, I.; Jalil J.E.; Orellana P.; Mellado R.; et al. Article SCOPUS Revista Medica de Chile (2010)
Iron induces protection and necrosis in cultured cardiomyocytes: Role of reactive oxygen species and nitric oxide Munoz, JP; Chiong M.; Garcia, L.; Troncoso R.; Toro, B; pedrozo, Z; Diaz-Elizondo, J; Salas, D.; Parra, V; Hidalgo C.; et al. Article ISI SCOPUS Free Radical Biology and Medicine (2010)
La sobreexpresión del gen de enzima convertidora de angiotensina homóloga (ECA2) revierte la hipertensión arterial y el remodelado cardíaco experimental Ramos, Elizabeth; Herrera, Alejandro; Moya, Jackeline; Apablaza, Felipe; Godoy, Ivan; Jalil, Jorge; Lavandero, Sergio; Chiong, Mario; Ocaranza, Maria Paz Article SCIELO Revista chilena de cardiologï¿½a (2010)
Matrix metalloproteinase-9 activity is associated to oxidative stress in patients with acute coronary syndrome Bittner, A.; Alcaíno, H.; Castro, PF.; Perez, O.; Corbalan, R.; Troncoso, R.; Chiong, M.; Mellado, R.; Moraga, F.; Zanolli, D.; Winter, JL.; Zamorano, JJ.; Diaz-Araya, G.; Lavandero, S. Article INTERNATIONAL JOURNAL OF CARDIOLOGY (2010)
Menores niveles tisulares de la enzima convertidora de angiotensina I homologa (ECA-2) y angiotensina-(1-9) están asociados a mayor remodelamiento de la pared aórtica de ratas hipertensas Ocaranza, Maria Paz; Moya, Jackeline; Pinto, Melissa; Escudero, Nicolas; Valenzuela, Francisco; Varas, Manuel; Godoy, Ivan; Chiong, Mario; Lavandero, Sergio; Jalil, Jorge Article SCIELO Revista chilena de cardiologï¿½a (2010)
Myocardial lipids and creatine measured by magnetic resonance spectroscopy among patients with heart failure Winter, JL; Castro P. ; Meneses L.; Chalhub M.; Verdejo H.; greig d.; Gabrielli, L; Chiong M.; Concepcion, R; Mellado R.; et al. Article ISI REVISTA MEDICA DE CHILE (2010)
Myocardial lipids and creatine measured by magnetic resonance spectroscopy among patients with heart failure [Determinaciones de niveles de creatina y lípidos mediante espectroscopia por resonancia magnética en miocardio de pacientes con insuficiencia cardiaca no isquémica] Meneses L.; Chalhub M.; Gabrielli, L; Chiong M.; ConcepciÃ³n R.; Mellado R.; Uribe, S. Article SCOPUS Revista Medica de Chile (2010)
Niveles aumentados de estrés oxidativo se asocian a disfunción endotelial periférica y respuesta vascular pulmonar disminuida frente a vasodilatadores en pacientes con hipertensión pulmonar Gabrielli, Luigi; Castro, Pablo; Chiong, Mario; Alcaino, Hernan; Verdejo, Hugo; Navarro, Mario; Greig, Douglas; Godoy, Ivan; Toro, Barbra; Quiroga, Clara; et al. Article SCIELO Revista chilena de cardiologï¿½a (2010)
Parallel activation of Ca2+-induced survival and death pathways in cardiomyocytes by sorbitol-induced hyperosmotic stress Chiong M.; Parra, V; Eisner V.; Ibarra, C; Maldonado, C; Criollo, A; Bravo, R.; Quiroga, C; Contreras, A; Cea, P; et al. Article ISI SCOPUS Apoptosis (2010)
(TTA)n Polymorphism in 3-Hydroxy-3-Methylglutaryl-Coenzyme A and Response to Atorvastatin in Coronary Artery Disease Patients Noriega V.; Pennanen C.; Sanchez, MP; Chiong M.; Llancaqueo, M; Lavandero S.; Prieto, JC Article ISI SCOPUS BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2009)
Differential Participation of Angiotensin II Type 1 and 2 Receptors in the Regulation of Cardiac Cell Death Triggered by Angiotensin II Aránguiz-Urroz, P; Soto, D; Contreras, A; Troncoso R.; Chiong M.; Montenegro, J.; Venegas, D; Smolic, C; Ayala, P; Thomas, WG; et al. Article ISI SCOPUS AMERICAN JOURNAL OF HYPERTENSION (2009)
El tratamiento con atorvastatina reduce la actividad de xantina-oxidasa unida al endotelio en pacientes con insuficiencia cardíaca crónica: ¿Un posible nuevo efecto pleiotrópico? Alcaino, Hernan; Castro, Pablo; Greig, Douglas; Verdejo, Hugo; Chiong, Mario; Garcia, Lorena; Gabrielli, Luigi; Diaz-Araya, Guillermo; Vukasovic, José Luis; Godoy, Ivan; et al. Article SCIELO Revista chilena de cardiologï¿½a (2009)
Gln(27)-> Glu beta(2)-Adrenergic Receptor Polymorphism in Heart Failure Patients: Differential Clinical and Oxidative Response to Carvedilol Troncoso R.; Moraga, F; Chiong M.; Roldan, J; Bravo, R.; Valenzuela R.; Diaz-Araya, G; del Campo, A; Sanhueza C.; Rodríguez A.; et al. Article ISI SCOPUS BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2009)
Neuronal Thy-1 induces astrocyte adhesion by engaging syndecan-4 in a cooperative interaction with alpha v beta 3 integrin that activates PKC alpha and RhoA Avalos, AM; Valdivia, AD; Muñoz, N.; Herrera-Molina, R; Lavandero S.; Chiong M.; Burridge, K; Schneider, P.; Quest, AFG; Leyton, L. Article ISI SCOPUS JOURNAL OF CELL SCIENCE (2009)
Regulatory volume decrease in cardiomyocytes is modulated by calcium influx and reactive oxygen species Rojas-Rivera, D; Diaz-Elizondo, J; Parra, V; Salas, D.; Contreras, A; Toro, B; Chiong M.; Olea Azar C.; Lavandero S. Article ISI SCOPUS FEBS LETTERS (2009)
The transcription factor MEF2C mediates cardiomyocyte hypertrophy induced by IGF-1 signaling Munoz, JP; Collao, A; Chiong M.; Maldonado, C; Adasme, T.; CARRASCO L.; Ocaranza, P; Bravo, R.; González L.; Diaz-Araya, G; et al. Article ISI SCOPUS BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
Ceramide-induced formation of ROS and ATP depletion trigger necrosis in lymphoid cells Villena, J; Henriquez, M.; Torres V.; Moraga, F; Diaz-Elizondo, J; Arredondo, C; Chiong M.; Olea Azar C.; Stutzin A.; Lavandero S.; et al. Article ISI SCOPUS FREE RADICAL BIOLOGY AND MEDICINE (2008)
Changes in mitochondrial dynamics during ceramide-induced cardiomyocyte early apoptosis Parra, V; Eisner V.; Chiong M.; Criollo, A; Moraga, F; Garcia, A.; Haertel, S.; Jaimovich E.; Zorzano, A; Hidalgo C.; et al. Article ISI SCOPUS CARDIOVASCULAR RESEARCH (2008)
Inflamación y disfunción endotelial en pacientes con insuficiencia cardiaca crónica Greig, Douglas; Castro, Pablo; Gabrielli, Luigi; Miranda, Rodrigo; Verdejo, Hugo; Alcaino, Hernan; Bustos, Carlos; Chiong, Mario; Godoy, Ivan; Mellado, Rosemarie; et al. Article SCIELO REVISTA MEDICA DE CHILE (2008)
Inflammation and endothelial dysfunction in patients with chronic heart failure greig d.; Castro P. ; Gabrielli, L; Miranda, R.; Verdejo H.; Alcaino H; Bustos C.; Chiong M.; Godoy, I.; Mellado R.; et al. Article ISI REVISTA MEDICA DE CHILE (2008)
Interacción entre los polimorfismos del receptor ß1 y ß2 adrenérgico como predictor de riesgo de insuficiencia cardiaca crónica Moraga, Francisco; Troncoso, Rodrigo; Mellado, Rosemarie; Diaz-Araya, Guillermo; Vukasovic, José Luis; Greig, Douglas; Pérez, Osvaldo; Garcia, Lorena; Roldán, Juan; Ocaranza, Maria Paz; et al. Article SCIELO REVISTA MEDICA DE CHILE (2008)
Interactions between beta(1) and beta(2) adrenergic receptor polymorphisms as risk factors for chronic heart failure Moraga, F; Troncoso R.; Mellado R.; Diaz-Araya, G; greig d.; Perez, O; Garcia, L.; Roldan, J; Jalil J.; Chiong M.; et al. Article ISI REVISTA MEDICA DE CHILE (2008)
Osmotically-induced genes are controlled by the transcription factor TonEBP in cultured cardiomyocytes Navarro P.; Chiong M.; Volkwein, K; Moraga, F; Lim, SW; Kim, JA; Kwon, HM; Lavandero S. Article ISI SCOPUS BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Phospholipase C/protein kinase C pathway mediates angiotensin II-dependent apoptosis in neonatal rat cardiac fibroblasts expressing AT1 receptor Vivar, R; Soto C.; Copaja M; Mateluna, F; Aranguiz, P; Munoz, JP; Chiong M.; Garcia, L.; Letelier, A; Thomas, WG; et al. Article ISI SCOPUS JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2008)
Pleiotropic effects of atorvastatin in heart failure: Role in oxidative stress, inflammation, endothelial function, and exercise capacity Miranda, R.; Verdejo, HE; greig d.; Gabrielli, LA; Alcaino H; Chiong M.; Bustos C.; Garcia, L.; Mellado R.; Godoy, I.; et al. Article ISI SCOPUS JOURNAL OF HEART AND LUNG TRANSPLANTATION (2008)
Serum uric acid correlates with extracellular superoxide dismutase activity in patients with chronic heart failure Alcaino H; greig d.; Chiong M.; Verdejo H.; Miranda, R.; Concepcion, R; Diaz-Araya, G; Mellado R.; Garcia, L.; Salas, D.; et al. Article ISI SCOPUS EUROPEAN JOURNAL OF HEART FAILURE (2008)
Uric acid, xanthine oxidase and heart failure: Unresolved issues Verdejo H.; Alcaíno, H.; Greig, D.; Garcia, L.; Pizarro, M.; Chiong, M.; Castro, P.; Lavandero, S. Article EUROPEAN JOURNAL OF HEART FAILURE (2008)
Estrés oxidativo e inflamación en insuficiencia cardiaca: Mecanismos de daño y alternativas terapéuticas Miranda H, Rodrigo; Castro G, Pablo; Verdejo P, Hugo; Chiong, Mario; Diaz-Araya, Guillermo; Mellado, Rosemarie; Rojas, Diego; Concepción, Roberto; Lavandera, Sergio Article SCIELO REVISTA MEDICA DE CHILE (2007)
Hyperosmotic stress activates p65/RelB NF kappa B in cultured cardiomyocytes with dichotomic actions on caspase activation and cell death Eisner V.; Quiroga, C; Criollo, A; Eltit, JM; Chiong M.; Parra, V; Hidalgo K.; Toro, B; Diaz-Araya, G; Lavandero S. Article ISI SCOPUS FEBS LETTERS (2006)
Hyperosmotic stress-dependent NF kappa B activation is regulated by reactive oxygen species and IGF-1 in cultured cardiomyocytes Eisner V.; Criollo, A; Quiroga, C; Olea Azar C.; Santibanez, JF; Troncoso R.; Chiong M.; Diaz-Araya, G; Foncea, R; Lavandero S. Article ISI SCOPUS FEBS LETTERS (2006)
Membrane electrical activity elicits inositol 1,4,5-trisphosphate-dependent slow Ca2+ signals through a G beta gamma/phosphatidylinositol 3-kinase gamma pathway in skeletal myotubes Eltit, JM; Garcia, AA; Hidalgo J.; Chiong M.; Lavandero S.; Maldonado E.; Jaimovich E. Article ISI SCOPUS JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Reactive oxygen species inhibit hyposmotic stress-dependent volume regulation in cultured rat cardiomyocytes Diaz-Elizondo, J; Chiong M.; Rojas-Rivera, D; Olea Azar C.; Kwon, HM; Lavandero S. Article ISI SCOPUS BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Testosterone induces an intracellular calcium increase by a nongenomic mechanism in cultured rat cardiac myocytes Ibarra, C; Estrada, M; Chiong M.; Soto, D; Parra, V; Diaz-Araya, G; Jaimovich E.; Lavandero S. Article ISI SCOPUS ENDOCRINOLOGY (2006)
Effects of carvedilol on oxidative stress and chronotropic response to exercise in patients with chronic heart failure Castro P. ; Chiong M.; Diaz-Araya, G; Alcaino H; Copaja M; Valenzuela R.; greig d.; Perez, O; Corbalan, R; Lavandero S. Article ISI SCOPUS EUROPEAN JOURNAL OF HEART FAILURE (2005)
Effects of Carvedilol upon intra- and interventricular synchrony in patients with chronic heart failure Mc-Nab, P; Quintana, JC; Bittner, A; greig d.; Vergara, I; Corbalan, R; Copaja M; Diaz-Araya, G; Chiong M.; Troncoso R.; et al. Article ISI SCOPUS AMERICAN JOURNAL OF CARDIOLOGY (2005)
IGF-1 protects cardiac myocytes from hyperosmotic stress-induced apoptosis via CREB Maldonado, C; Cea, P; Adasme, T.; Collao, A; Diaz-Araya, G; Chiong M.; Lavandero S. Article ISI SCOPUS BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Oxidative stress in pericardial fluid and plasma and its association with ventricular function Moraga, F; Diaz-Araya, G; Turner E.; Chiong M.; Uriarte, P; Florenzano, F; Lavandero S. Article ISI SCOPUS INTERNATIONAL JOURNAL OF CARDIOLOGY (2005)
Effects of carvedilol on functional capacity, left ventricular function, catecholamines and oxidative stress in patients with chronic heart failure Castro P. ; Perez, O; greig d.; Diaz-Araya, G; Moraga, F; Chiong M.; Troncoso R.; Padilla I.; Corbalan, R; Lavandero S. Article ISI REVISTA ESPANOLA DE CARDIOLOGIA (2004)
Effects of carvedilol on functional capacity, left ventricular function, catecholamines and oxidative stress in patients with chronic heart failure Efectos del carvedilol en la capacidad funcional, función ventricular izquierda, catecolaminas y estrés oxidativo en pacientes con insuficiencia cardíaca crónica Castro P. ; Perez, O; greig d.; Padilla I.; Corbalan, R; Diaz-Araya, G; Moraga, F; Chiong M.; Troncoso R.; Lavandero S.; et al. Article SCOPUS REVISTA ESPANOLA DE CARDIOLOGIA (2004)
Insulin-like growth factor-1 induces an inositol 1,4,5-trisphosphate-dependent increase in nuclear and cytosolic calcium in cultured rat cardiac myocytes Ibarra, C; Estrada, M; CARRASCO L.; Chiong M.; Cardenas C; Diaz-Araya, G; Jaimovich E.; Lavandero S. Article ISI SCOPUS JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Aldose reductase induced by hyperosmotic stress mediates cardiomyocyte apoptosis - Differential effects of sorbitol and mannitol Ulloa, JA; Chiong M.; Criollo, A; Eisner V.; Barros, LF; Lavandero S. Article ISI SCOPUS JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Levels of plasma angiotensin-(1-7) in patients with hypertension who have the angiotensin-1-converting enzyme deletion/deletion genotype Palomera, C; GODOY, L.; Román M.; Chiong M.; Lavandero S. Article ISI SCOPUS AMERICAN JOURNAL OF CARDIOLOGY (2003)
Relation between oxidative stress, catecholamines, and impaired chronotropic response to exercise in patients with chronic heart failure secondary to ischemic or idiopathic dilated cardiomyopathy greig d.; Perez, O; Moraga, F; Chiong M.; Diaz-Araya, G; Padilla I.; Nazzal C.; Moreno, M.; Corbalan, R; Lavandero S. Article ISI SCOPUS AMERICAN JOURNAL OF CARDIOLOGY (2003)
Isoproterenol and angiotensin I-converting enzyme in lung, left ventricle, and plasma during myocardial hypertrophy and fibrosis Diaz-Araya, G; Chiong M.; Muñoz D; Riveros, JP; Ebensperger, R; Sabat, S; Irarrázaval P.; Lavandero S. Article ISI SCOPUS JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2002)
Oxidative stress after reperfusion with primary coronary angioplasty: Lack of effect of glucose-insulin-potassium infusion Diaz-Araya, G; Nettle, D; Castro P. ; Miranda F.; greig d.; Campos X; Chiong M.; Nazzal C.; Corbalan, R; Lavandero S. Article ISI SCOPUS CRITICAL CARE MEDICINE (2002)
Persistence of oxidative stress after heart tranplantation: A comparative study of patients with heart transplant versus chronic stable heart failure Perez, O; Castro P. ; Diaz-Araya, G; Nettle, D; Moraga, F; Chiong M.; Jalil J.; Zalaquett R.; Moran S.; Becker P.; et al. Article SCOPUS REVISTA ESPANOLA DE CARDIOLOGIA (2002)
Persistence of oxidative stress after heart transplantation: A comparative study of patients with heart transplant versus chronic stable heart failure Perez, O; Castro P. ; Diaz-Araya, G; Nettle, D; Moraga, F; Chiong M.; Jalil J.; Zalaquett R.; Moran S.; Becker P.; et al. Article ISI REVISTA ESPANOLA DE CARDIOLOGIA (2002)
Direct electrochemical characterization of hyperthermophilic Thermococcus celer metalloenzymes involved in hydrogen production from pyruvate Smith, ET; Odom, LD; Awramko, JA; Chiong M.; Blamey, J. Article ISI JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY (2001)
Purification and characterization of an iron-nickel hydrogenase from Thermococcus celer Blamey, Jm; Chiong M.; Smith, ET Article ISI JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY (2001)
VARIANTES GENETICAS DE LOS RECEPTORES ADRENERGICOS Y ENFERMEDADES CARDIOVASCULARES Castro, Pablo; Chiong, Mario; Corbalán Ramón; Diaz, Guillermo; Lavandero, Sergio; Moraga, Francisco; Moreno, Mauricio Article REVISTA CHILENA DE CARDIOLOGIA (2001)
Purification and characterization of ferredoxin from the hyperthermophilic Pyrococcus woesei Blamey, Jm; Chiong M.; López C.; Smith, ET Article ISI ANAEROBE (2000)
Optimization of the growth conditions of the extremely thermophilic microorganisms Thermococcus celer and Pyrococcus woesei Blamey, J.; Chiong M.; López C.; Smith E. Article JOURNAL OF MICROBIOLOGICAL METHODS (1999)
Citrus limon seedlings without functional chloroplasts are unable to induce phenylalanine ammonia-lyase in response to inoculation with Alternaria alternata Prieto H.; Chiong M.; Seelenfreund, D; Garrido, J.; Quaas, A; PEREZ, L.M. Article JOURNAL OF PLANT PHYSIOLOGY (1997)
Kinetic characteristics of nucleoside mono-, di- and triphosphatase activities of the periplasmic 5'-nucleotidase of Escherichia coli Garcia, L.; Chayet L; Kettlun A.M.; Collados, L; Chiong M.; Traverso-Cori A.; Mancilla, M.; Valenzuela M.. A Article COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY MOLECULAR BIOLOGY (1997)
Omeprazole, a specific gastric secretion inhibitor on oxynticopeptic cells, reduces gizzard erosion in broiler chicks fed with toxic fish meals Neira M.; López C.; Chiong M.; Ocaranza M.P.; Gallardo, R.; Rutman, M; Blamey, J.; Lavandero S. Article Comparative Biochemistry and Physiology - C Pharmacology Toxicology and Endocrinology (1997)


Angiotensin-(1-9) Prevents Cardiomyocyte Hypertrophy Through Calcium Influx Dependent Pathway Hechenleitner, J; González L.; Chiong M.; Jalil J.; Lavandero S. Abstract HYPERTENSION (2011)
Angiotensin-(1-9) Prevents the Cardiovascular Pathological Remodeling Induced by Angiotensin II In Vivo Lagos T.; Moya, J; Morales C. ; González L.; Novoa U.; Chiong M.; Lavandero S.; Jalil J. Abstract HYPERTENSION (2011)
Evidence of impaired cardiac autophagic flux in patients developing post-operative atrial fibrillation Kuzmicic J.; Verdejo H.; Garcia, L.; Gonzalez S.; pedrozo, Z; Toro, B; Zalaquett R.; Chiong M.; Lavandero S.; Corbalan, R Abstract EUROPEAN HEART JOURNAL (2010)
Angiotensin II triggers apoptosis in cardiac fibroblast but not in myofibroblast overexpressing the type 1 receptor Diaz-Araya, GA; Sanchez, RV; Soto C.; Copaja M; Mateluna, F; Aranguiz, P; Munoz, JP; Chiong M.; Thomas, WG; Lavandero S. Abstract FEBS JOURNAL (2007)
Activity of metalloproteinase-9 is related to oxidative stress in the acute coronary syndrome Bittner, A; Castro P. ; Perez, O; Alcaino H; Troncoso R.; Chiong M.; Diaz-Araya, G; Lavandero S. Abstract EUROPEAN HEART JOURNAL (2006)
Extracellular endothelium-bound superoxide dismutase is a sensitive oxidative stress marker in heart failure patients Castro P. ; Miranda, R.; Ferrada M.; Alcaino H; Chiong M.; Concepcion, R Abstract CIRCULATION (2006)
A signal transduction mechanism linking dihydropyridine receptors and phospholipase C in myotubes Eltit, JM; Hidalgo J.; Chiong M.; Lavander, S; Jaimovich E. Abstract BIOPHYSICAL JOURNAL (2005)
Carvedilol corrects interventricular and interventricular dyssynchrony in chronic heart failure. Mc-Nab, P; Bittner, A; greig d.; Quintana, JC; Chiong M.; Diaz-Araya, G; Valenzuela R.; Vergara, I; Corbalan, R; Lavandero S. Abstract JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2005)
Apoptosis induced by hyperosmotic stress Eisner V.; Quiroga, C; Criollo, A; Olea, C; Diaz-Araya, G; Chiong M.; Lavandero S. Abstract FREE RADICAL BIOLOGY AND MEDICINE (2004)
Decrease in oxidative stress is not related to left ventricular function improvement in patients with chronic heart failure treated with carvedilol greig d.; Castro P. ; Chiong M.; Moraga, F; Diaz-Araya, G; Perez, O; Lavandero S. Abstract EUROPEAN HEART JOURNAL (2004)
Gene expression of profibrotic factors in isoproterenol-treated Brown-Norway and Lewis rats Soto, MC; Bassi, RV; Saldaña A.; Ocaranza M.; Jalil J.; Chiong M.; Lavandero S.; Diaz-Araya, G Abstract MOLECULAR BIOLOGY OF THE CELL (2004)


Ácido úrico: una molécula con acciones paradójicas en la insuficiencia cardiaca Alcaino, Hernan; Greig, Douglas; Castro, Pablo; Verdejo, Hugo; Mellado, Rosemarie; Garcia, Lorena; Diaz-Araya, Guillermo; Quiroga, Clara; Chiong, Mario; Lavandero, Sergio ComunicacionBreve SCIELO SCOPUS REVISTA MEDICA DE CHILE (2011)


Mechanisms of cell death: molecular insights and therapeutic perspectives Diaz, LF; Chiong M.; Quest, AFG; Lavandero S.; Stutzin A. EditorialMaterial ISI SCOPUS CELL DEATH AND DIFFERENTIATION (2005)


Dissociating angiotensin 1-9 anticardiovascular remodeling effects from those on blood pressure Reply Michea, L.; Chiong M.; Lavandero S. Letter ISI SCOPUS JOURNAL OF HYPERTENSION (2014)
Matrix metalloproteinase-9 activity is associated to oxidative stress in patients with acute coronary syndrome Bittner, A; Alcaino H; Perez, O; Corbalan, R; Troncoso R.; Chiong M.; Mellado R.; Moraga, F; Zanolli D.; Winter, JL; et al. Letter ISI SCOPUS International Journal of Cardiology (2010)
Uric acid, xanthine oxidase and heart failure: Unresolved issues Verdejo H.; greig d.; Castro P. ; Alcaino H; Garcia, L.; Chiong M.; Lavandero S.; Pizarro M. Letter ISI EUROPEAN JOURNAL OF HEART FAILURE (2008)


Activation of ACE2 in endothelial small extracellular vesicles protect the myocardium against myocardial infarction in high fat diet fed mice Riquelme, Jaime A.; Chiong, Mario Proyecto (2023)
Proyecto Asociativo Regional Explora Región Metropolitana Norte Chiong, Mario Proyecto (2023)
Role of S-nitrosylation in vascular smooth muscle cell senescence and vascular dysfunction in an experimental model of heart failure with preserved ejection fraction (HFpEF) Chiong, Mario Proyecto (2022)
Participación de MUL1 en el acoplamiento retículo sarcoplásmico-mitocondria en la hipertrofia del cardiomiocito inducida por angiotensina II Garrido, Valeria Proyecto (2021)
Proyecto Asociativo Regional de Divulgación y Valoración Científica y Tecnológica Explora Región Metropolitana Norte Chiong, Mario Proyecto (2019)
Autocrine/paracrine interleukin-6 and myostatin control of VSMC differentiation under exercise and resting Proyecto (2018)
Autocrine/paracrine interleukin-6 and myostatin control of VSMC differentiation under exercise and resting FONDECYT (1180157) Proyecto 2018-2021 Inv. Responsable
Shedding of vascular cell adhesion molecules predicts adverse cardiovascular events in patients submitted to cardiac surgery Proyecto (2018)
Shedding of vascular cell adhesion molecules predicts adverse cardiovascular events in patients submitted to cardiac surgery FONDECYT (1181147) Proyecto 2018-2021 Coinvestigador(a)
Cardiac remodeling and biological response in highly trained athletes=> study with myocardial deformation imaging and biomarkers at baseline and post-intensive acute exercise FONDECYT (1170963) Proyecto 2017-2019 Coinvestigador(a)
Cardiac remodeling and biological response in highly trained athletes: study with myocardial deformation imaging and biomarkers at baseline and post-intensive acute exercise Proyecto (2017)
Papel de los exosomas provenientes de células endoteliales en el precondicionamiento miocárdico inducido por dexmedetomidina Proyecto (2016)
Sistema de PCR digital de última generación Proyecto (2016)
PAPEL DE LOS EXOSOMAS PROVENIENTES DE CÉLULAS ENDOTELIALES EN EL PRECONDICIONAMIENTO MIOCÁRDICO INDUCIDO POR DEXMEDETOMIDINA FONDECYT (3160298) Proyecto 2015-2018 Inv. Patrocinante
Comprehensive evaluation of right ventricular function, ventricular remodeling and micro RNA profiling in pulmonary artery hypertension=> Effects of a fatty acid oxidation inhibitor FONDECYT (1141198) Proyecto 2014-2018 Coinvestigador(a)
Dual role of autophagy in the regulation of vascular smooth muscle cell phenotype dependent of mTOR activation Proyecto (2014)
DUAL ROLE OF AUTOPHAGY IN THE REGULATION OF VASCULAR SMOOTH MUSCLE CELL PHENOTYPE DEPENDENT ON MTOR ACTIVATION FONDECYT (1140329) Proyecto 2014-2018 Inv. Responsable
Evaluation of right ventricular function, ventricular remodeling and micro RNA profiling in patients with pulmonary artery hypertension: Effects of a fatty acid oxidation inhibitor Proyecto (2014)
EVALUATION OF RIGHT VENTRICULAR FUNCTION, VENTRICULAR REMODELING AND MICRO RNA PROFILING IN PATIENTS WITH PULMONARY ARTERY HYPERTENSION=> EFFECTS OF A FATTY ACID OXIDATION INHIBITOR FONDECYT (1141198) Proyecto 2014-2018 Coinvestigador(a)
Unidad de Microscopía de Dinámica Celular Proyecto (2014)
Advanced Center for Chronic Diseases (ACCDiS). Ferreccio, Catherina Proyecto (2013)
Advanced Center of Chronic Diseases (ACCDiS) FONDAP (15130011) Proyecto 2013-2018 Coinvestigador(a)
Angiotensina-(1-9), un nuevo principio activo para el tratamiento de la hipertensión y del daño cardiovascular y renal secundarios=> estudio y desarrollo preclínicos FONDEF (11I1122) Proyecto 2013-2016 Coinvestigador(a)
Equipo de ultracentrifugación con cuatro rotores Proyecto (2013)
Plataforma de microscopía confocal para uso en investigaciones biomédicas avanzadas Proyecto (2013)
Angiotensina-(1-9), un nuevo principio activo para el tratamiento de la hipertensión y del daño cardiovascular y renal secundarios: estudio y desarrollo preclínicos. Proyecto (2012)
Bioenergética celular Proyecto (2012)
Desarrollo de una plataforma tecnológica para análisis cuantitativos, cualitativo y de distribución subcelular de proteínas Proyecto (2012)
La regulación diferencial de FOXO1 y FOXO3a por TGF-beta1, modula tanto la diferenciación como el aumento de la actividad antiapoptótica/antioxidante de fibroblastos cardiacos Proyecto (2012)
Metabolic stress signaling in cancer, cardiovascular diseases and diabetes. PIA (ACT1111) Proyecto 2012-2015 Coinvestigador(a)
Metabolic stress signaling in cancer, cardiovascular diseases and diabetes. Casa, Mariana Proyecto (2012)
The incretin Glucagon-Like Peptide I: Study of new metabolic mechanisms in vascular remodeling. Proyecto (2011)
The incretin Glucagon-Like Peptide I=> Study of new metabolic mechanisms in vascular remodeling. FONDECYT (1110180) Proyecto 2011-2014 Inv. Responsable
Angiotensin-(1-9): a new peptide regulator of blood pressure that decreases cardiovascular remodeling and renal injury Proyecto (2010)
Angiotensin-(1-9)=> a new peptide regulator of blood pressure that decreases cardiovascular remodeling and renal injury. FONDECYT (1100874) Proyecto 2010-2014 Coinvestigador(a)
Metabolismo cardiaco en la insuficiencia cardiaca crónica no isquémica y sus implicancias en el estrés oxidativo, inflamación y remodelado cardiovascular. FONDECYT (1090727) Proyecto 2009-2013 Coinvestigador(a)
Metabolismo cardíaco en la insuficiencia cardíaca crónica no isquémica y sus implicancias en el estrés oxidativo, inflamación y remodelado cardiovascular. Proyecto (2009)
Resistencia a insulina en la diabetes tipo II: estudio de nuevos mecanismos fisiopatológicos asociados al deterioro de la función cardiaca Proyecto (2008)
Resistencia a insulina en la diabetes tipo II=> estudio de nuevos mecanismos fisiopatológicos asociados al deterioro de la función cardiaca. FONDECYT (1080436) Proyecto 2008-2012 Coinvestigador(a)
Mecanismos de protección cardiovascular dependientes de la enzima convertidora de angiotensina I homóloga (ECA2) en la hipertensión arterial experimental FONDECYT (1070662) Proyecto 2007-2009 Coinvestigador(a)
Mecanismos de protección cardiovascular dependientes de la enzima convertidora de angiotensina I homóloga (ECA2) en la hipertensión arterial experimental Proyecto (2007)
Estrés oxidativo, inflamación y disfunción endotelial en la insuficiencia cardiaca crónica: Efectos de la inhibición de la xantino-oxidasa y 3-hidroxi-3-metilglutaril-coA reductasa. Proyecto (2005)
Estrés oxidativo, inflamación y disfunción endotelial en la insuficiencia cardiaca crónica=> efectos de la inhibición de la xantino-oxidasa y 3 hidroxi 3 metilglutaril-Coa reductasa FONDECYT (1050769) Proyecto 2005-2009 Coinvestigador(a)
Obtención de quitosano a partir de desechos de krill antártico y sus aplicaciones biotecnológicas Proyecto (1998)
Aislamiento de los cDNA que codifican para los genes de resistencia a fitopatógenos en Citrus Proyecto (1990)
Importancia de la actividad ADPásica en vegetales, animales y microorganismos Proyecto (1990)
Evaluación técnico-económica para la producción de proteasas desde ciegos pilóricos de jurel, con aplicaciones en aditivos para alimentos de peces e hidrólisis de proteínas de pescado Proyecto (0)
Implementación de una plataforma para caracterizar nanoestructuras (tamaño, potencial zeta, concentración y fluorescencia) de interés en diversas disciplinas Proyecto (0)


ACE2 and vasoactive peptides: Novel players in cardiovascular/renal remodeling and hypertension Mendoza-Torres, E; Oyarzun A.; Azocar, A.; Castro P.F.; Jalil J.E.; Chiong M.; Lavandero S.; Ocaranza M.P. Review SCOPUS Therapeutic Advances In Cardiovascular Disease (2015)
Autophagy in cardiovascular biology Lavandero S.; Chiang M.; Rothermel BA; Hill, JA Review ISI SCOPUS Journal of Clinical Investigation (2015)
Molecular Mechanisms of Autophagy in the Cardiovascular System Gatica, D; Chiong M.; Lavandero S. Review ISI SCOPUS Circulation Research (2015)
Novel players in cardioprotection: Insulin like growth factor-1, angiotensin-(1-7) and angiotensin-(1-9) Westermeier, F; Bustamante, M; Pavez, M.; Garcia, L.; Chiong M.; Lavandero S. Review ISI SCOPUS Pharmacological Research (2015)
Recent insights and therapeutic perspectives of angiotensin-(1-9) in the cardiovascular system Ocaranza, Maria Paz; Michea, Luis; Chiong, Mario; Lagos, Carlos F; Lavandero, Sergio; Jalil, Jorge E. Review ISI SCOPUS CLINICAL SCIENCE (2014)
Influence of glucose metabolism on vascular smooth muscle cell proliferation Chiong M.; Morales PE; Torres, G; Gutiérrez T.; Garcia, L.; Ibacache M; Michea, L. Review ISI SCOPUS Vasa - Journal of Vascular Diseases (2013)
Autophagy as a therapeutic target in cardiovascular disease Nemchenko A.; Chiong M.; Turer A.; Lavandero S.; Hill, JA Review ISI SCOPUS Journal of Molecular and Cellular Cardiology (2011)
Cardiomyocyte death: mechanisms and translational implications Chiong M.; Wang, ZV; pedrozo, Z; Cao, DJ; Troncoso R.; Ibacache M; Criollo, A; Nemchenko A.; Hill, JA; Lavandero S. Review ISI SCOPUS Cell Death and Disease (2011)
Mitochondrial Dynamics: a Potential New Therapeutic Target for Heart Failure Kuzmicic J.; del Campo, A; López-Crisosto, C; Morales PE; Pennanen C.; Bravo Sagua R; Hechenleitner, J; Zepeda, R.; Verdejo, HE; Parra, V; et al. Review ISI SCOPUS REVISTA ESPANOLA DE CARDIOLOGIA (2011)
Heart energy metabolism and its role in the treatment of heart failure Castro P. ; Gabrielli, L; Verdejo H.; greig d.; Mellado R.; Concepcion, R; Sepulveda, L; Garcia, L.; Pizarro M.; Pivet, D; et al. Review ISI REVISTA MEDICA DE CHILE (2010)
Metabolismo energético del corazón y sus proyecciones en el tratamiento de la insuficiencia cardíaca Castro, Pablo; Gabrielli, Luigi; Verdejo, Hugo; Greig, Douglas; Mellado, Rosemarie; Concepción, Roberto; Sepúlveda, Luis; Vukasovic, José Luis; Garcia, Lorena; Pizarro, Marcela; et al. Review SCIELO REVISTA MEDICA DE CHILE (2010)
Oxidative stress and inflammation in heart failure: Mechanisms of damage and therapeutic alternatives Miranda, R.; Castro P. ; Verdejo H.; Chiong M.; Diaz-Araya, G; Mellado R.; Rojas D.; Concepcion, R; Lavandero S. Review ISI REVISTA MEDICA DE CHILE (2007)
Rho/Rho kinase signal transduction pathway in cardiovascular disease and cardiovascular remodeling Jalil J.; Lavandero S.; Chiong M. Review ISI SCOPUS REVISTA ESPANOLA DE CARDIOLOGIA (2005)

Sergio Uribe

Associated professor

Radiology

PONTIFICIA UNIVERSIDAD CATÓLICA

Santiago, Chile

Steffen Härtel

Full Professor

Instituto de Ciencias Biomédicas

University of Chile

Santiago, Chile

Enrique Jaimovich

Full Professor

ICBM

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

Manuel Estrada

/Associate Professor / PI

Physiology and Biophysics

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA, INSTITUTO DE CIENCIAS BIOMÉDICAS (ICBM), PROGRAMA DE FISIOLOGÍA Y BIOFÍSICA

Santiago, Chile

Gareth Owen

Profesor Titular

Fisiologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Maria González

Academico

FACULTAD DE MEDICINA - UNIVERSIDAD DE CHILE

Santiago, Chile

Edio Maldonado

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA

Santiago, Chile

Juan Carlos Quintana

Médico nuclear

Radiología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Eugenio Ramírez

INSTITUTO DE SALUD PÚBLICA DE CHILE

Santiago, Chile

Guillermo Díaz

Académico

Química Farmacológica y Toxicológica

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

JORGE JALIL

FULL PROFESSOR

ENFS CARDIOVASCULARES

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, ESCUELA DE MEDICINA

Santiago, Chile

110

SERGIO LAVANDERO

Director

Advanced Center for Chronic Diseases (ACCDiS)

UNIVERSIDAD DE CHILE, FAC CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

205

Mario Chiong

Profesor

Departamento de Bioquímica y Biología Molecular

Universidad de Chile

Santiago, Chile

Gina Sanchez

Profesor Asociado

ICBM

UNIVERSIDAD DE CHILE, FAC MEDICINA , ICBM

Santiago, Chile

Marcelo Kogan

Academico

Quimica Farmacologica y Toxicologica

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

fresia ferreccio

Full Professor, Director PhD Epidemiolgy Program

Public Health

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE FACULTAD DE MEDICINA, ESCUELA DE MEDICINA, DEPARTAMENTO DE SALUD PÚBLICA.

Santiago, Chile

Andrew Quest

Full Professor

Biologia Celular y Molecular

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

Felipe Simon

Profesor Titular

Department of Biological Sciences

UNIVERSIDAD ANDRES BELLO FAC DE CS BIOLOGICAS, DPTO DE CS BIOLOGICAS

Santiago, Chile

Andres Stutzin

Full Professor

ICBM

FACULTAD DE MEDICINA UNIVERSIDAD DE CHILE

Santiago, Chile

Claudio Hetz

Deputy Director

INSTITUTO DE CIENCIAS BIOMÉDICAS, FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

SANTIAGO, Chile

Jorge Ferreira

Director

Clinic and Molecular Farmacology

UNIVERSIDAD DE CHILE , FACULTAD DE MEDICINA, ICBM

Santiago, Chile

claudio olea

Full Professor

Inorganica y Analitica

UNIVERSIDAD DE CHILE

Santiago, Chile

JUAN VILLENA

FULL PROFESSOR

ANATOMY

FACULTA DE MEDICINA. UNIVERSIDAD DE VALPARAISO

VIÑA DEL MAR, Chile

Clemente Palacios

Académico

Química y Farmacia

Universidad Arturo Prat

Iquique, Chile

Rosemarie Mellado

Jefe de carrera / Académica

Farmacia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Juan Prieto

Profesor Titular

Programa de Farmacología Molecular y Clínica

Universidad de Chile

Santiago, Chile

FRANCISCO NUALART

Full Professor and Scientific Director

Cellular Biology and Center for Advanced Microscopy CMA BIO-BIO

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

Enrique Brandan

Profesor Titular

Biología Celular y Molecular

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

Marco Nuñez

Professor

Biology

Fac. Ciencias, Universidad de Chile

Santiago, Chile

Ramon Corbalan

Director

Division of Cardiovascular Diseases

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

Lorena Garcia

Assistant Professor

Bioquimica y Biologia Molecular

UNIVERSIDAD DE CHILE

Santiago, Chile

Luis Barros

Principal Research

Laboratorio Biología Molecular

CENTRO DE ESTUDIOS CIENTÍFICOS

Valdivia, Chile

Tatiana Adasme

Coordinadora de Estudios

Oficina de Apoyo a la Investigación Clínica

Universidad Chile

Santiago, Chile

Rodrigo Troncoso

Assistant professor

Universidad de Chile, Instituto de Nutrición y Tecnología de los Alimentos

Santiago de Chile, Chile

Vicente Torres

Associate Professor

Institute for Research in Dental Sciences

FACULTAD DE ODONTOLOGÍA - UNIVERSIDAD DE CHILE

Santiago, Chile

Lisette Leyton

Full Professor

Cell and Molecular Biology

FACULTAD DE MEDICINA UNIVERSIDAD DE CHILE

Santiago, Chile

Mauricio Henriquez

Profesor asistente

PROGRAMA DE FISIOLOGÍA Y BIOFíSICA

Universidad de Chile / Facultad de Medicina

Santiago, Chile

Ariel Castro

Full Professor

Department of Biochemistry and Molecular Biology

UNIVERSIDAD DE CONCEPCION

concepciòn, Chile

Juan Orellana

Associate Professor

Departamento de Neurología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Diego Rojas

Assistant Professor

Center for Integrative Biology

Universidad Mayor

Santiago, Chile

Clara Quiroga

Profesor Asistente Adjunto

División de Enfermedades Cardiovasculares

Pontificia Universidad Católica de Chile

Santiago, Chile

Pablo Sepúlveda

Cardiólogo Intervencionista

División de Enfermedades Cardiovasculares

Pontificia Universidad Católica de Chile

Santiago, Chile

Jenny Blamey

Director Científico

Research and Development

FUNDACIÓN CIENTÍFICA Y CULTURAL BIOCIENCIA

Santiago, Chile

Universidad de Aysén

Coyhaique, Chile

Claudio Cabello

Full Professor

Ciencias Biologicas

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

Ana Riveros

Profesor Asistente

Departamento de Química Farmacológica y Toxicológica

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS QUIMICAS Y FARMACÉUTICAS

Santiago, Chile

Raúl Vivar

Profesor Asistente

Universidad de Chile

Santiago, Chile

Mario Bustamante

Docente

Universidad Mayor de Chile

Santiago, Chile

Ariel Contreras

assistance professor

Institute for Research in Dental Science

UNIVERSIDAD DE CHILE

Santiago, Chile

Mariana Cifuentes

Professor

Instituto de Nutricion y Tecnologia de los Alimentos

INTA UNIVERSIDAD DE CHILE

Santiago, Chile

CLAUDIA BAMBS

PROFESORA ASOCIADA

SALUD PÚBLICA

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Pablo Irarrazaval

Professor

Electrical Engineering

Pontificia Universidad Católica de Chile

Santiago, Chile

Roberto Ebensperger

Associate Professor

Pharmacy

Pontificia Universidad Católica de Chile

Santiago, Chile

Jaime Riquelme

Assistant Professor

Química Farmacológica y Toxicológica

Universidad de Chile

Santiago, Chile

Elen Quispe

Académico

Facultad de Ciencias de la Salud

Universidad Arturo Prat

IQUIQUE, Chile

Julio Benites

Profesor Titular

Química y Farmacia

Universidad Arturo Prat

Iquique, Chile

Luis Michea

PROFESOR ASOCIADO

PROGRAMA FISIOLOGIA Y BIOFISICA

UNIVERSIDAD DE CHILE

Santiago, Chile

M. Cecilia Hidalgo

Professor

ICBM

Universidad de Chile

Santiago, Chile

Carlos Lagos

Profesor Asociado

FACULTAD DE MEDICINA Y CIENCIA

UNIVERSIDAD SAN SEBASTIÁN

SANTIAGO, Chile

Rodrigo Alzamora

ASSISTANT PROFESSOR

INSTITUTE OF BIOMEDICAL SCIENCES

UNIVERSIDAD DE CHILE

Santiago, Chile

Julio Cardenas

Associated Professor

Center for Integrative Biology

Universidad Mayor de Chile

Santiago, Chile

Berta Espinosa

Full Professor

Tecnología Médica

Universidad de Chile

Santiago, Chile

JULIO TAPIA

Full Professor

Program of Cellular and Molecular Biology

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

Alfredo Criollo

Associated Professor

Research Institute in Dental Sciences

Facultad de Odontología, Universidad de Chile

Santiago, Chile

LUIS SOBREVIA

Professor

Division of Obstetrics and Gynaecology

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

Jovan Kuzmicic

Profesor Asistente

Departamento Salud

Universidad de Los Lagos

Osorno, Chile

Andrea del Campo

Profesor Asistente, Investigador Principal

Departamento de Farmacia

Pontificia Universidad Católica de Chile

Santiago, Chile

Valentina Parra

Profesora Asistente / Assistant Professor

Departamento de Bioquímica y Biología Molecular

UNIVERSIDAD DE CHILE

Santiago, Chile

MANUEL VARAS

Research Professor

UNIVERSIDAD SAN SEBASTIÁN

Santiago, Chile

Adrian Paredes

Academico

Química

UNIVERSIDAD DE ANTOFAGASTA

Antofagasta, Chile

Roberto Bravo

Assistant Professor

Institute of Nutrition and Food Technology (INTA), Universidad de Chile

Santiago, Chile

Pablo Aránguiz

Jefe de Carrera

Escuela de Ciencias de la Salud

Universidad Vina del Mar

Viña del Mar, Chile

daniel hevia

Investigador PhD

Inmunologia

Universidad de Chile

santiago, Chile

Eugenia Morselli

Profesor Asociado de Planta Ordinaria

Fisiología

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago de Chile, Chile

Carlos Lafourcade

Profesor Asociado

UNIVERSIDAD DE LOS ANDES

Chile

Pedro Buc

Profesor titular

Quimica y Farmacia

Universidad Arturo Prat

Iquique, Chile

Luigi Gabrielli

Profesor Asistente

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Chile

Rodrigo Valenzuela

Postdoctorado

Oftalmología

Universidad de Chile

Santiago, Chile

Juan Santibáñez

Professor of Research

Molecular Oncology

Institute for Medical Research

Belgrade, Serbia

Yenniffer Ávalos

Profesor Asistente

Departamento de Biología

Universidad de Santiago de Chile

Santiago, Chile

MARIO SIMIRGIOTIS

full professor

Facultad de Ciencias

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

Dagoberto Soto

Investigador

Universidad Católica de Chile

santiago, Chile

Elias Utreras

Profesor Asistente

Biologia

Universidad de Chile

Santiago, Chile

Ivonne Olmedo

Assistant Profesor

Programa de Fisiopatología

Universidad de Chile

Santiago, Chile

Leticia Gonzalez

Profesional Apoyo a la Investigacion

Pontificia Universidad Católica de Chile

Santiago, Chile

Javier Morales

Profesor Asociado

Departamento de Ciencias y Tecnología Farmacéuticas

Universidad de Chile

Santiago, Chile

Francisco Morales

Posdoctoral

Universidad de Chile. Centro FONDAP ACCDiS

Santiago, Chile

Carolina Nazzal

Profesor Asociado

Instituto de Salud Poblacional

Universidad de Chile

Santiago, Chile

Maria Ocaranza

Full Professor

Cardiovascular Diseases Division

Pontificia Universidad Catolica de Chile

Santiago, Chile

Rodrigo Troncoso

Associate Professor

Instituto de Nutrición y Tecnología de los Alimentos

Santiago, Chile

Zully Pedrozo

Associated Professor

Physiology and Biophysical

Universidad de Chile

SANTIAGO DE CHILE, Chile

Veronica Eisner

Associate Professor

Cellular and Molecular Biology

Pontificia Universidad Católica de Chile

Santiago, Chile

Hugo Verdejo

Profesor Asociado

División de Enferemedades Cardiovasculares

Pontificia Universidad Católica de Chile

Santiago, Chile

Daniela Salas

Ramiro Zepeda

Academico

Farmacologia y neurociencia

universidad de Chile

santiago, Chile

Rodrigo Herrera

Group Leader (staff member)

Combinatorial NeuroImaging Core Facility

Leibniz Institute for Neurobiology

Magdeburg, Alemania

Camila López

Mauricio Ibacache

Profesor Asociado

Pontificia Universidad Católica de Chile

santiago centro, Chile

Carlos Sepulveda

Investigador Postdoctoral

Instituto de Nutrición y Tecnología de los Alimentos, Universidad de Chile.

Santiago, Chile

Jorge Borquez

Académico

Química

Universidad de Antofagasta

Antofagasta, Chile

Matias Monsalves

Profesor Asistente

Instituto de Ciencias de la Rehabilitación

Universidad Andrés Bello

Santiago, Chile

FELIPE CONTRERAS

Professor / Director (Head) Laboratorio Fisiología del Ejercicio

Kinesiología

Pontificia Universidad Católica de Chile

Santiago, Chile

Douglas Greig

Médico Jefe

Cardiología

P. Universidad Católica de Chile

Santiago, Chile

Pedro Ayala

Profesor investigador asistente

Departamento de Enfermedades Respiratorias

Pontificia Universidad Católica de Chile

Santiago, Chile

Gonzalo Martínez

Director

División de Enfermedades Cardiovasculares

Hospital Clínico Universidad Católica

Santiago, Chile

Claudia Muñoz

Postdoctorado

Universidad de Chile

Santiago, Chile

Constanza Núñez

Investigadora

Pontificia Universidad Católica de Valparaíso

Valparaíso, Chile

Daniel Peña

Investigador postdoctoral

Departamento de Fisiología

Pontificia Universidad Católica de Chile

Santiago, Chile

Maria Pando

Profesor asistente

Nutrición

Universidad de Chile

Santiago, Chile

Maria Valenzuela

Profesor TItular

Bioquimica y Biología Molecular

Universidad de Chile

Santiagao, Chile

Pablo Castro

JEFE DIVISION

DIVISION ENFERMEDADES CARDIOVASCULARES

Pontificia Universidad Católica de Chile

SANTIAGO, Chile

Eduardo Silva

Investigador Postdoctoral

Universidad Mayor

Santiago, Chile

Ignacio Norambuena

Postdoctorado

Universidad de Chile

Santiago, Chile

Arnaldo Marín

Profesor Adjunto

Basico Clinico de Oncologia

Universidad de Chile

Santiago, Chile

Luis Garrido

Profesor Asistente Asociado

Cirugia

Pontificia Universidad Católica de Chile

Santiago, Chile

MONICA ZAGOLIN

COORDINADOR PROGRAMA

DOCENCIA Y MEDICINA

INSTITUTO DEL TORAX

santiago, Chile

María Sánchez

Académica

Biología

Universidad de Santiago de Chile

Santiago, Chile

Paulina Villar

Tesista doctorado en bioquímica

Bioquímica

Universidad de Chile

Santiago, Chile

Andrea Ramírez

Asistente de Investigación

Bioquímica

Universidad de Chile

Región Metropolitana, Chile

Sebastián Leiva

Lab Manager

Bioquímica y Biología Molecular

Universidad de Chile

Santiago, Chile

Magda Díaz

Anita Gálvez

Profesor Asistente

Biomédico

Universidad de Antofagasta

Antofagasta, Chile

Yvo Flores

Profesional (grado 12)

Biomédico

Instituto de Salud Pública

Santiago, Chile

ALEJANDRA SAN MARTIN

Professor

Medicine

Universidad Andrés Bello

Santiago, Chile

Juan Bórquez

Docente

Kinesiologia

Universidad de Magallanes

Punta Arenas, Chile

GLORIA TORRES

Investigadora Postdoctoral

CIIB

Universidad de Los Andes

Santiago, Chile

Fernanda Sanhueza

Bioquímica

Hospital Base San José de Osorno

Osorno, Chile

Jessica Díaz

Profesional especialista

Universidad Andrés Bello

Santiago, Chile

Mario Martín Chiong Lay

Líneas de Investigación

Educación

Doctor en Farmacología, Universidad de Chile. Chile, 2009

Bioquímico, Universidad de Chile. Chile, 1986

Licenciado en Bioquímica, Universidad de Chile. Chile, 1986

Experiencia Académica

Profesor Asociado Full Time

Ayudante Full Time

Profesor Asistente Full Time

Profesor Titular Full Time

Experiencia Profesional

Associate Professor Full Time

Full Professor Full Time

Formación de Capital Humano

Difusión y Transferencia

Premios y Distinciones

Premio "Mejor Docente"

Premio "Mejor Docente"

Scholarship “The British Council”,

Scholarship "Beca Presidente de la República"

Colegio de Químicos Farmacéuticos Award

Premio "Mejor Docente"

Premio "Mejor Docente"

Premio "Mejor Docente"

Mejor Docente de Pregrado de la Universidad de Chile 2014

Premio "Mejor Docente"

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