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LUIS ALBERTO SOBREVIA LUARTE

Professor

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

Líneas de Investigación


Role of adenosine and insulin receptors and membrane transporters as modulators of fetal vascular function in gestational diabetes, preeclampsia and ovarian cancer. Mechanisms associated with nitric oxide, arginases glucose and lipids metabolism.

Educación

  •  BSc Hons. Biological Sciences, UNIVERSIDAD DEL BIO-BIO. Chile, 1986
  •  Physiology, UNIVERSIDAD DE CONCEPCION. Chile, 1990
  •  Physiology and Biomedicine, Kings College London, UK. Reino Unido, 1996

Experiencia Académica

  •   Instructor in Physiology Full Time

    UNIVERSIDAD DEL BIO-BIO

    Chillán, Chile

    1986 - 1990

  •   Assistant Professor of Physiology Full Time

    King´s College London

    Chillán, Chile

    1991 - 1992

  •   Assistant Professor of Physiology, Universidad de Concepción Full Time

    UNIVERSIDAD DE CONCEPCION

    Concepción, Chile

    1997 - 1999

  •   Associate Professor of Physiology Full Time

    UNIVERSIDAD DE CONCEPCION

    Concepción, Chile

    2000 - 2003

  •   Associate Adjunct Professor Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Faculty of Medicine

    Santiago, Chile

    2003 - 2005

  •   Associate Professor Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Faculty of Medicine

    Santiago, Chile

    2005 - 2012

  •   Professor Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Faculty of Medicine

    Santiago, Chile

    2012 - A la fecha

  •   Honorary Professor Other

    UNIVERSITY OF QUEENSLAND

    Medicine and Biomedical Sciences

    Australia

    2012 - A la fecha

  •   Honorary Professor Other

    UNIVERSIDAD DE SEVILLA

    Pharmacy

    España

    2014 - A la fecha

Experiencia Profesional

  •   Instructor in Physiology Full Time

    Universidad del Bío-Bío

    Chillán, Chile

    1986 - 1990

  •   Assistant Professor of Physiology, Full Time

    Universidad del Bío-Bío

    Chillán, Chile

    1991 - 1992

  •   Associate Researcher Full Time

    King´s College London (KCL)

    London, Reino Unido

    1996 - 1997

  •   Assistant Professor of Physiology Full Time

    Universidad de Concepción

    Concepción, Chile

    1997 - 1999

  •   Associate Professor of Physiology Full Time

    Universidad de Concepción

    Concepción, Chile

    2000 - 2003

  •   Associate Adjunct Professor Full Time

    Pontificia Universidad Católica de Chile

    Santiago, Chile

    2003 - 2005

  •   Associate Professor Full Time

    Pontificia Universidad Católica de Chile

    Santiago, Chile

    2005 - 2012

  •   Professor Full Time

    Pontificia Universidad Católica de Chile

    Santiago, Chile

    2012 - A la fecha

  •   Honorary Professor Full Time

    University of Queensland Centre for Clinical Research (UQCCR)

    Brisbane, Australia

    2012 - A la fecha

  •   Honorary Professor Full Time

    Universidad de Sevilla

    Sevilla, España

    2014 - A la fecha

Formación de Capital Humano


1995 Ago - 1996 Ago: [Tutor Unidad de Investigación] Ciencias Biomédicas. Usman Jaffer. Characterization of calcium signals in micro- and macrovascular human endothelial cells. (School of Biomedical Sciences, King´s College London) , University of London, Inglaterra

1996 Ago - 1997 Mar: [Tutor Unidad de Investigación] Ciencias Biomédicas. Elizabeth Meddows. Effect of elevated glucose on calcium signals in micro and macrovascular endothelial cells. (School of Biomedical Sciences, King´s College London) , University of London, Inglaterra

1996 Jun - 1997 May: [Tutor Unidad de Investigación] Ciencias Biomédicas. Philipp Malchour. Effect of elevated glucose and antioxidants on L-arginine/nitric oxide pathway. (School of Biomedical Sciences, King´s College London) , University of London, Inglaterra

1996 Mar - 1997 Mar: [Tutor Tesis Magíster] Roxana Contreras. Ruta de señalización L-arginina/NO en glándulas gástricas aisladas de conejos diabéticos. MSc Ciencias (Fisiología), Facultad de Ciencias Biológicas , Universidad de Concepción

1997 - 1997: [Clases Pregrado] Fisiología Gastrointestinal (Carrera de Odontología, Facultad de Odontología) , Universidad de Concepción

1997 - 1999: [Clases postgrado] Curso Post-grado/Post-título Ginecología. Tópico Mecanismos moleculares de la regulación de la ruta L-arginina/NO en endotelio fetal humano en diabetes mellitus. Curso Ciencias Biológicas aplicadas en Obstetricia. Horas 2. , Universidad de Concepción

1997 - 2001: [Clases Pregrado] Fisiología (sistema hormonal) (Carrera de Bioquímica, Facultad de Ciencias Biológicas) , Universidad de Concepción

1997 - 2002: [Clases Pregrado] Fisiología (sistema hormonal) (Carrera de Química y Farmacia, Facultad de Ciencias Biológicas) , Universidad de Concepción

1997 - 2002: [Clases Pregrado] Fisiología (sistema gastrointestinal) (Carrera de Química y Farmacia, Facultad de Ciencias Biológicas) , Universidad de Concepción

1997 - 2002: [Clases Pregrado] Fisiología Unidad de Investigación (Carrera de Bioquímica, Facultad de Ciencias Biológicas) , Universidad de Concepción

1997 - 2002: [Clases Pregrado] Fisiología Seminarios Bibliográficos (Carrera de Bioquímica, Facultad de Ciencias Biológicas) , Universidad de Concepción

1997 - 2002: [Clases postgrado] Doctorado en Ciencias Biológicas mención Biología Celular y Molecular. Tópico Transporte de L-arginina y síntesis de óxido nítrico. Curso Neurociencias. Horas 8. Código 401.864. , Universidad de Concepción

1997 Jul - 1997 Dic: [Tutor Unidad de Investigación] Bioquímica. Claudio Morales. Implementación de la técnica de cultivo de células musculares lisas humanas normales y diabéticas , Universidad de Concepción

1997 Mar - 1997 Jul: [Tutor Unidad de Investigación] Bioquímica. Loreto Carvallo. Técnica de cultivo de células endoteliales humanas , Universidad de Concepción

1997 Mar - 1997 Jul: [Tutor Unidad de Investigación] Bioquímica. Yerko Arancibia. Técnica de cultivo de células endoteliales humanas. , Universidad de Concepción

1997 Sep - 1997 Sep: [Clases pregrado] Cell Physiology JP/0353. Glucose transport in microvascular endothelial cells (School of Biomedical Sciences, King´s College London) , University of London, Inglaterra

1998 - 2002: [Clases Pregrado] Seminarios Bibliográficos (Carrera de Medicina, Facultad de Medicina) , Universidad de Concepción

1998 Ago - 1999 Dic: [Tutor Tesis Magíster] Viviana Montecinos. Efecto de hiperglicemia y ATP extracelular en el transporte de adenosina en células endoteliales fetales humanas. MSc Ciencias (Fisiología), Facultad de Ciencias Biológicas , Universidad de Concepción

1998 Jul - 1998 Dic: [Tutor Unidad de Investigación] Bioquímica. Mónica Brito. Participación de PKC en la regulación del transporte de adenosina en endotelio humano diabético , Universidad de Concepción

1998 Jul - 1998 Dic: [Tutor Unidad de Investigación] Bioquímica. Angélica Reyes. Participación de PKC en la regulación del transporte de adenosina en endotelio humano diabético , Universidad de Concepción

1998 Jul - 1998 Dic: [Tutor Unidad de Investigación] Bioquímica. Yerko Arancibia. Regulación del transporte de L-arginina por el sisyema y+L en endotelio humano diabético Mónica Brito (3-6/1998) , Universidad de Concepción

1998 Mar - 1998 Jul: [Tutor Unidad de Investigación] Bioquímica. Angélica Reyes. Regulación del transporte de adenosina en endotelio humano por PKC , Universidad de Concepción

1998 Mar - 1998 Jul: [Tutor Unidad de Investigación] Bioquímica. Yerko Arancibia. Caracterización del transporte de L-arginina por el sisyema y+L en endotelio humano , Universidad de Concepción

1999: [Examinador externo] Tesis Doctorado Biología Celular y Molecular. Valentina Echeverría. Caracterización de la actividad de adenilil ciclasa in vitro. , Universidad de Concepción

1999: [Clases postgrado] Doctorado en Ciencias Biológicas mención Biología Celular y Molecular, Tópico Transporte de Nucleósidos, Curso Biología Celular, Horas 8, Código 401.851. , Universidad de Concepción

1999 Abr - 1999 Jul: [Tutor Unidad de Investigación] Bioquímica. Ingrid Carvacho. Modulación del transporte de L-arginina en eritrocitos de pacientes adictos a cocaina , Universidad de Concepción

1999 Abr - 1999 Jul: [Tutor Unidad de Investigación] Bioquímica. Gustavo Vásquez. Modulación del transporte de adenosina por alta glucosa en endotelio humano. , Universidad de Concepción

1999 Abr - 2001 Jul: [Tutor Unidad de Investigación] Bioquímica. Silvia Olivares. Modulación del transporte de adenosina por alta glucosa en endotelio humano , Universidad de Concepción

1999 Jul - 1997 Dic: [Tutor Unidad de Investigación] Bioquímica. Loreto Carvallo. Implementación de la técnica de cultivo de células musculares lisas humanas normales y diabéticas , Universidad de Concepción

1999 Jul - 1999 Dic: [Tutor Unidad de Investigación] Bioquímica. Gustavo Vásquez. Efecto de diabetes sobre el transporte de adenosina modulado por MAPK p42/44 en endotelio humano , Universidad de Concepción

1999 Jul - 2000 Mar: [Tutor Tesis Magíster] Claudio Aguayo. Regulación del transporte y metabolismo de adenosina en músculo liso vascular fetal humano. MSc Ciencias (Fisiología), Facultad de Ciencias Biológicas , Universidad de Concepción

1999 Jul - 2000 Mar: [Tutor Tesis Magíster] Claudio Aguayo. Regulación del transporte y metabolismo de adenosina en músculo liso vascular fetal humano. MSc Ciencias (Fisiología), Facultad de Ciencias Biológicas , Universidad de Concepción

1999 Mar - 2001 Oct: [Tutor Tesis Magíster] Carlos Flores. Caracterización del efecto agudo de D-glucosa sobre el transporte de L-arginina en endotelio fetal humano. MSc Ciencias (Fisiología), Facultad de Ciencias Biológicas , Universidad de Concepción

2000: [Examinador externo] Tesis de Título Bioquímica. Tamara Castro. Interacción fisiológica y estructural entre nervios simpáticos y mastocitos en útero de ratón. Facultad de Farmacia. , Universidad de Concepción

2000: [Examinador interno] Tesis Doctorado Biología Celular y Molecular. Virginia Vega. Rol de los mediadores inflamatorios producidos por las células de Kupffer en la injuria oxidativa sobre hepatocitos de ratas sometidas a shock por torniquete. , Universidad de Concepción

2000 - 2000: [Clases Pregrado] Biología vascular(Carrera de Medicina, Facultad de Medicina) , Universidad de Concepción

2000 - 2002: [Clases Pregrado] Bioquímica III Unidad de Investigación(Carrera de Bioquímica, Facultad de Ciencias Biológicas) , Universidad de Concepción

2000 - 2002: [Clases postgrado] Post-grado/Post-título en Ginecología. Tópico El endotelio fetal y la diabetes gestacional. Curso Ciencias Biológicas aplicadas en Obstetricia. Horas 2. , Universidad de Concepción

2000 - 2003: [Clases postgrado] Doctorado en Ciencias Biológicas mención Biología Celular y Molecular, Tópico Regulación del Transporte Biológico, Curso Biología Celular, Horas 8, Código 401.851. , Universidad de Concepción

2000 Abr - 2000 Jul: [Tutor Unidad de Investigación] Bioquímica. Fabián Arenas. Participación de proteína kinasa G en la modulación del transporte de L-arginina en hiperglicemia en endotelio humano , Universidad de Concepción

2000 Abr - 2000 Jul: [Tutor Unidad de Investigación] Bioquímica. Jéssica Moreno. Regulación de la expresión de CAT-1 y CAT-2B en endotelio humano , Universidad de Concepción

2000 Abr - 2000 Jul: [Tutor Unidad de Investigación] Bioquímica. Jéssica Moreno. Efecto agudo de D-glucosa sobre el transporte de L-arginina en endotelio humano , Universidad de Concepción

2000 Dic - 2003 Abr: [Tutor Tesis Magíster] Paola Casanello. Efecto de hipoxia fetal sobre la expresión génica de los sistemas hENTs y CATs en endotelio fetal humano. MSc Ciencias (Fisiología), Facultad de Ciencias Biológicas , Universidad de Concepción

2000 Mar - 2003 Abr: [Tutor Tesis Magíster] Liliana Lamperti. Transporte de L-arginina y síntesis de NO en linfocitos T y endotelio humano: efecto de LDL. MSc Ciencias (Bioquímica), Facultad de Biológicas, , Universidad de Concepción

2000 Mar - 2004 Sep: [Tutor Tesis Doctorado] Claudio Aguayo. Modulación de la expresión de transportadores hENT1 en hiperglicemia en endotelio fetal humano. PhD Ciencias Biológicas (Area Biología Celular y Molecular), Facultad de Ciencias Biológicas , Universidad de Concepción

2001: [Curso dictado] Programa Magíster en Ciencias Biológicas (mención Fisiología), Curso Aspectos Biofísicos del Transporte Biológico, Créditos 4, Código 406.883. , Universidad de Concepción

2001: [Curso dictado] Programas Doctorado en Ciencias Biológicas (Area Biología Celular y Molecular), Magíster en Ciencias Biológicas (mención Fisiología). Curso Regulación del Transporte Biológico: Fisiología y Fisiopatología, Créditos 4, Código 401.419. , Universidad de Concepción

2001 - 2003: [Clases postgrado] Doctorado en Ciencias Biológicas mención Biología Celular y Molecular, Tópico Bases Biofísicas del Transporte de Membrana. Curso Regulación del Transporte de Membrana: Fisiología y Fisiopatología. Horas 8, Código 406.883. , Universidad de Concepción

2001 - 2003: [Clases postgrado] Magister en Ciencias mención Fisiología. Tópico Cinéticas de Transporte. Curso Biofísica del transporte de membrana: Fisiología y Fisiopatología. Horas 45. Código 401.419. , Universidad de Concepción

2001 - 2004: [Clases postgrado Profesor Visitante] Fisiología Celular: Adenosina–Arginina y su regulacion funcional. , Universitat de Barcelona (España)

2001 Ago - 2002 Abr: [Tutor Tesis Pregrado] Yerko Arancibia . Caracterización del sistema de transporte y+L para aminoácidos catiónicos en endotelio fetal humano. Carrera de Bioquímica, Facultad de Farmacia , Universidad de Concepción

2001 Jul - 2001 Dic: [Tutor Unidad de Investigación] Bioquímica. Rodrigo Grandy. Rol de LDL oxidada como modulador de la localización subcelular de MAP kinasas en endotelio humano. , Universidad de Concepción

2001 Jul - 2001 Dic: [Tutor Unidad de Investigación] Bioquímica. Alfredo Yori. Localización subcelular de MAP kinasas en respuesta a alta D-glucosa en endotelio humano , Universidad de Concepción

2001 Jul - 2001 Dic: [Tutor Unidad de Investigación] Bioquímica. Andrea Bello. Modulación del transporte de adenosina por LDL oxidada en endotelio humano , Universidad de Concepción

2001 Jul - 2001 Dic: [Tutor Unidad de Investigación] Bioquímica. Karina Godoy. Rol de cAMP y cGMP en la modulación de la incorporación de timidina a macromoléculas en hiperglicemia en endotelio humano , Universidad de Concepción

2001 Jul - 2001 Dic: [Tutor Unidad de Investigación] Bioquímica. Paula Guzmán. Ruta de señalización celular asociada a insulina en la modulación del transporte de L-arginina en endotelio humano , Universidad de Concepción

2001 Oct - 2002 Abr: [Tutor Tesis Pregrado] Ingrid Carvacho (Co-Supervisor, c/Dr F Sepúlveda, CECS Valvidia). Líneas celulares para el estudio de la función del canal de cloruro CIC-5 en intestino. Carrera de Bioquímica, Facultad de Farmacia , Universidad de Concepción

2002: [Examinador externo] Proyecto Tesis de Título de Bioquímica. Ingrid Carvacho. Líneas celulares para el estudio de la función del canal de cloruro CIC-5 en intestino. , Universidad de Concepción

2002: [Clases postgrado] Doctorado en Neurociencias. Curso Biofísica Avanzada. Tópico Modelos de transporte a través de membranas biológicas. , Universidad de Valparaíso

2002: [Curso dictado] Programa Magíster en Ciencias Biológicas (mención Fisiología), Curso Aspectos Biofísicos del Transporte Biológico, Créditos 4, Código 401.419 , Universidad de Concepción

2002: [Clases postgrado Profesor Visitante] Doctorado y Magister en Ciencias. Fisiología Celular: Adenosina–Arginina y su regulacion functional. , Universidad de Sao Pablo (Brasil)

2002 - 2003: [Clases Pregrado] Fisiología (sistema neurohormonal, neuromuscular) (Carrera de Bioquímica, Facultad de Ciencias Biológicas) , Universidad de Concepción

2002 Abr - 2002 Jul: [Tutor Unidad de Investigación] Bioquímica. Marcelo González. MEK/ERKS y su papel en la modulación de la expresión y actividad de la ruta L-arginina/óxido nítrico por insulina en endotelio fetal humano. , Universidad de Concepción

2002 Abr - 2002 Jul: [Tutor Unidad de Investigación] Bioquímica. Pamela Pastén. Transporte de adenosina en HUVECs de retardo de crecimiento intrauterino (RCIU) , Universidad de Concepción

2002 Abr - 2002 Jul: [Tutor Unidad de Investigación] Bioquímica. Alfredo Yori. Modulación del transporte de adenosina por insulina en endotelio fetal humano. , Universidad de Concepción

2002 Abr - 2002 Jul: [Tutor Unidad de Investigación] Bioquímica. Gustavo Vásquez. Participación de TGF-B1 en el efecto de alta D-glucosa sobre la ruta L-arginina/óxido nítrico endotelial , Universidad de Concepción

2002 Ene - 2003 Ene: [Tutor Tesis Pregrado] Gustavo Vásquez. Regulación de la ruta L-arginina/NO en endotelio fetal humano de diabetes gestacional. Carrera de Bioquímica, Facultad de Farmacia , Universidad de Concepción

2002 Mar - 2002 Jul: [Curso dictado] Programas Doctorado en Ciencias Biológicas (Area Biología Celular y Molecular), Magíster en Ciencias Biológicas (mención Fisiología). Curso Regulación del Transporte Biológico: Fisiología y Fisiopatología. Créditos 4, Código 406.883 , Universidad de Concepción

2003: [Tutor Unidad de Investigación] PhD en Ciencias Biomédicas. Valeria Mezzano. Efecto de insulina sobre la via L-arginina/NO en la restricción de crecimiento intrauterino: transporte de L-arginina y expresión de transportadores de aminoácidos catíónicos en endotelio de vena de cordón umbilical humana. , Pontificia Universidad Católica de Chile

2003: [Examinador] Revisión Bibliográfica. PhD en Ciencias Médicas. Sergio Rey. Regulación de la vasodilatación neurogénica: interacción de los efectos celulares del péptido relacionado al gen de la calcitonina y NO a nivel de nucleótidos cíclicos en un modelo experimental in vivo de migraña. Facultad de Medicina , Pontificia Universidad Católica de Chile

2003: [Examinador externo] Tesis Doctorado Ciencias Biomédicas. Marcela Julio. Participación del factor de crecimiento nervioso en la regulación de la angiogénesis ovárica. Facultad de Medicina. , Universidad de Chile

2003 - 2009: [Clases postgrado] Doctorado en Ciencias Médicas. Tópico Diabetes y Endotelio. Curso Procesos Biológicos Básicos en Enfermedades Humanas. Horas 4. Código MD01020. , Pontificia Universidad Católica de Chile

2003 Abr - 2003 Jul: [Tutor Unidad de Investigación] Bioquímica. Gonzalo Muñoz. Insulina modula el efecto de D-glucosa sobre el transporte de adenosina en endotelio fetal humano. , Universidad de Concepción

2003 Abr - 2003 Jul: [Tutor Unidad de Investigación] Bioquímica. Felipe Sanhueza. Insulina modula el transporte de adenosina en endotelio fetal humano de restricción de crecimiento intrauterino. , Universidad de Concepción

2003 Ago - 2004 Mar: [Tutor Tesis Pregrado] Romina Rojas. Modulación de la expresión de transportadores hENT1 en endotelio fetal humano expuesto a hipoxia. Carrera de Química y Farmacia, Facultad de Farmacia , Universidad de Concepción

2003 Dic - 2006 Jul: [Tutor Tesis Doctorado] Rodrigo Vásquez. Papel del factor de crecimiento transformate B1 en la estimulacion de la via L-arginin-Oxido nitrico por altos niveles de D-glucosa en celulas endoteliales de vena umbilical humana. PhD en Ciencias Medicas, Facultad de Medicina , Pontificia Universidad Catolica de Chile

2003 May - 2003 Dic: [Tutor Post-Doctorado] Programa de formación de Post-Doctorado. Eduardo López. Clonning of ENTs from human fetal endothelium (Facultad de Medicina) , Pontificia Universidad Catolica de Chile

2004: [Clases postítulo] Curso de Obstetricia y Ginecología. Horas 2. , Pontificia Universidad Católica de Chile

2004: [Clases postgrado] Doctorado y Magíster en Ciencias. Tópico Endotelio e hipoxia. Curso Insultos Metabólicos y Vasculares que Afectan el Desarrollo del CNS: Oportunidades terapéuticas. Horas 2. Código SONEPSYN 2004. , Universidad de Chile

2004: [Examinador externo] Tesis Doctorado Ciencias Biomédicas. Pamela Cornejo. Sobrecarga crónica de hierro en la rata: rol hepatoprotector del óxido nítrico. Facultad de Medicina. , Universidad de Chile

2004: [Examinador externo] Tesis Doctorado en Bioquímica. Lorena García. Efecto de la infección del virus HTL-1 sobre proteínas de matriz extracelular y citoesqueleto neuronal del sistema nervioso central. Implicancia en la paraparesia espástica tropical. Facultad de Farmacia , Universidad de Chile

2004: [Tutor Revisión Bibliográfica] MSc Bioquímica. Victoria Gallardo. Pre-eclampsia y alteraciones en la expresión de transportadores de membrana en endotelio humano. , Pontificia Universidad Católica de Chile

2004: [Tutor Unidad de Investigación] MSc en Bioquímica. Victoria Gallardo. Caracterización funcional y molecular de la ruta L-arginina/NO en endotelio de placenta de embarazos con preeclampsia. , Pontificia Universidad Católica de Chile

2004: [Clases postgrado Profesor Visitante] Doctorado y Magister en Ciencias. Fisiología Celular: Moléculas de señalización placenta-feto. , Universidad de Sao Pablo (Brasil)

2004: [Examinador externo] Tesis Doctorado Ciencias Biológicas, c/m Fisiología. Andrés Rodríguez. Efecto de hiperglicemia en la expresión y transducción de señales del receptor B1 de bradicinina. Facultad de Ciencias Biológicas. , Pontificia Universidad Católica de Chile

2004: [Examinador interno] Tesis Doctorado Ciencias Médicas. Sergio Rey. Efecto de la hipoxia intermitente en la actividad quimiosensorial carotídea: rol de endotelina 1. Facultad de Medicina. , Pontificia Universidad Católica de Chile

2004 - 2009: [Clases postgrado] Doctorado en Ciencias Biológicas (mención Fisiología). Tópico Transporte Mediado. Curso Biofísica. Horas 6. Código BIO-448. , Pontificia Universidad Católica de Chile

2004 Abr - 2004 Jun: [Clases Pregrado] Curso BIO238C Seminarios de investigación (Carrera de Medicina, Facultad de Medicina) , Pontificia Universidad Católica de Chile

2004 Ago - 2006 Dic: [Tutor Tesis Doctorado] Marcelo Farias. Mecanismos de regulacion de la actividad transcripcional de hENT1 en endotelio de vena umbilical humana de gestaciones afectadas por diabetes. PhD en Ciencias Medicas, Facultad de Medicina , Pontificia Universidad Catolica de Chile

2004 Ene - 2004 Ago: [Tutor Tesis Pregrado] Marcelo González. Regulación de la ruta L-arginina/NO por insulina en endotelio fetal humano. Carrera de Bioquímica, Facultad de Farmacia , Universidad de Concepción

2004 Ene - 2005 Dic: [Tutor Post-Doctorado] Programa de formación de Post-Doctorado. Rody San Martín. siRNA as a tool in medical research (Facultad de Medicina) , Pontificia Universidad Catolica de Chile

2004 Mar - 2006 Mar: [Tutor Tesis Doctorado] Paola Casanello. Mecanismos de transduccion de señales que regulan la ruta L-arginina/NO en endotelio de vena umbilical humana de gestaciones afectadas por restriccion de crecimiento intrauterino. PhD en Ciencias Biologicas (m/Ciencias Fisiologicas), Facultad de Ciencias Biologicas , Pontificia Universidad Catolica de Chile

2004 May - 2004 May: [Clases Pregrado] Curso BIO241B Patología Molecular (Carrera de Bioquímica, Facultad de Ciencias Biológicas) , Pontificia Universidad Católica de Chile

2005: [Examinador externo] Tesis de Título de Bioquímica. Karen Pérez. Homocisteína y biogénesis mitocondrial en células endoteliales. Papel del estrés oxidativo. , Pontificia Universidad Católica de Chile

2005: [Examinador externo] Tesis Doctorado Ciencias Médicas. Kurl Schalper. Hemicanales, rol de factores neurotróficos. Facultad de Medicina. , Pontificia Universidad Católica de Chile

2005: [Examinador externo] Tesis Doctorado Ciencias Biomédicas. Sebastián Cabrera. Facultad de Medicina, Instituto de Ciencias Biomédicas. , Universidad de Chile

2005 - 2005: [Tutor Seminario de Investigación Departamental] BIO295 Bioquímica. Luis Cea. Efecto de insulina en el transporte de adenosina en endotelio fetal humano expuesto a insulina. , Pontificia Universidad Catolica de Chile

2005 - 2005: [Tutor Seminario de Investigación Departamental] BIO295 Bioquímica. Carlos Puebla. Estabilidad del mRNA de hENT1 y hENT2 en endotelio fetal humano expuesto a insulina expuesto a alta D-glucosa. , Pontificia Universidad Catolica de Chile

2005 - 2009: [Clases postgrado Profesor Visitante] Doctorado en Ciencias Biológicas. Tópico Biofísica de transporte activo. , Universidad de Antofagasta

2005 - 2009: [Clases postgrado] Curso de postgrado Endocrinología Reproductiva. Tópico Endotelio y disfunción en diabetes gestacional. Horas 2. , Universidad de Chile

2005 - 2009: [Clases postgrado] Curso de Post-grado/Post-título Reproducción. Tópico Mecanismos moleculares de la regulación de la ruta L-arginina/NO en endotelio fetal humano. Horas 2. , Universidad de Chile

2005 - 2009: [Clases postgrado Profesor Visitante]Magister en Ciencias Médicas. Tópico Diabetes gestacional y disfunción endotelial fetal. , Universidad de Antofagasta

2005 - 2009: [Profesor Invitado, miembro de staff] Curso Metodología de la Investigación. Post-titulo en Medicina, Especialidades. , Pontificia Universidad Católica de Chile

2005 Abr - 2005 Jun: [Clases Pregrado] Curso BIO238C Seminarios de investigación (Carrera de Medicina, Facultad de Medicina) , Pontificia Universidad Católica de Chile

2005 Dic - 2006 Dic: [Tutor Tesis Pregrado] Gonzalo Muñoz. Insulina modula el efecto de D-glucosa sobre el transporte de adenosina en endotelio fetal humano. Carrera de Bioquímica, Facultad de Farmacia , Universidad de Concepción

2005 Ene - 2005 Mar: [Tutor Práctica extramural] BIO258A-1 Bioquímica. Francisco Minaya. Parámetros clínicos en células sanguíneas y marcadores de disfunción endotelial , Pontificia Universidad Católica de Chile

2005 Mar - 2005 Jul: [Tutor Seminario de Investigación Departamental] BIO295 Bioquímica. Francisco Minaya. Transporte de adenosina regulada por adenosina en endotelio fetal humano , Pontificia Universidad Católica de Chile

2005 Mar - 2005 Jul: [Tutor Seminario de Investigación Departamental] BIO295 Biología. Roberto Reyes. Regulación por insulina del transporte de arginina en hipoxia en endotelio fetal humano , Pontificia Universidad Católica de Chile

2005 Mar - 2006 Dic: [Co-Tutor Tesis Magíster (c/P Casanello)] Victoria Gallardo. L-Arginina y reactividad vascular placentaria human en restricción de crecimiento intrauterino. MSc en Bioquímica, Facultad de Ciencias Biológicas , Pontificia Universidad Católica de Chile

2005 Mar - 2008 Dic: [Tutor Tesis Doctorado] Marcelo Gonzalez. Señalizacion por insulina en endotelio fetal humano de diabetes gestacional. PhD en Ciencias Biologicas (m/Ciencias Fisiologicas), Facultad de Ciencias Biologicas , Pontificia Universidad Catolica de Chile

2005 Mar - 2008 Mar: [Tutor Tesis Doctorado] Carlos Escudero. Función endotelial fetal humana en preecampsia. PhD en Ciencias Medicas, Facultad de Medicina , Pontificia Universidad Catolica de Chile

2005 May - 2005 May: [Clases Pregrado] Curso BIO241B Patología Molecular (Carrera de Bioquímica, Facultad de Ciencias Biológicas) , Pontificia Universidad Católica de Chile

2006 - 2009: [Tutor Tesis Doctorado] Jose Luis Vega, MSc. Mecanismos de señalizacion de TGFb1 asociados a la regulacion de la expresion de hENT1 en endotelio de vena umbilical humana. PhD en Ciencias Biologicas (m/Ciencias Fisiologicas), Facultad de Ciencias Biologicas , Pontificia Universidad Catolica de Chile

2006 - 2009: [Clases postgrado en el extranjero] Facultad de Biología Doctorado y Magíster en Bioquímica , Universidad de Barcelona, España

2006 Ago - 2007 Mar: [Tutor Tesis Pregrado] Biologia. Catalina Prieto. Regulacion de la actividad de NOS por hipoxia en endotelio fetal humano. Carrera de Biologia, Facultad de Ciencias Biológicas , Pontificia Universidad Catolica de Chile

2006 Ago - 2007 Mar: [Tutor Tesis Pregrado] Bioquímica. Carlos Puebla. Regulacion de la union de Sp1 al promotor de SLC29A1 por glucosa en endotelio fetal humano. Carrera de Bioquímica, Facultad de Ciencias Biológicas , Pontificia Universidad Catolica de Chile

2006 Dic - 2008 Mar: [Tutor Tesis Pregrado] Felipe Sanhueza. Retardo de crecimiento intrauterinoento (IUGR) en el transporte de adenosina en endotelio fetal. Carrera de Bioquímica, Facultad de Farmacia , Universidad de Concepción

2006 Mar - 2006 Dic: [Tutor Tesis Pregrado] Bioquímica. Luis Cea. Efecto de insulina en hipoxia sobre la regulación del transporte de adenosina en endotelio fetal humano. Carrera de Bioquímica, Facultad de Ciencias Biológicas , Pontificia Universidad Catolica de Chile

2006 Mar - 2007 Feb: [Tutor Post-Doctorado] Programa de formación de Post-Doctorado. Andrea Vecchiola. ChIP as a tool in medical research (Facultad de Medicina) , Pontificia Universidad Catolica de Chile

2006 Mar - 2009 Mar: [Tutor Tesis Pregrado] Bioquímica. Francisco Minaya. Regulación del transporte de adenosina por adenosina en endotelio fetal humano. Carrera de Bioquímica, Facultad de Ciencias Biológicas (alumno realizó estadía de investigación por dos años en España). , Pontificia Universidad Católica de Chile

2007 - 2008: [Tutor Tesis Doctorado] Luis Cea. Mecanismos de senalizacion de insulina en la regulacion de la expresion de SLC29A2 en endotelio humano de diabetes gestacional. PhD en Ciencias Biologicas (m/Ciencias Fisiologicas), Facultad de Ciencias Biologicas , Pontificia Universidad Catolica de Chile

2007 - 2008: [Profesor Invitado] Curso de post-titulo Reproduccion y Desarrollo. Facultad de Medicina. , Universidad de Valparaiso

2007 - 2008: [Clases postgrado en el extranjero] Facultad de Ciencias Biologicas, Doctorado y Magíster en Ciencias , Universidad de Parma, Italia

2007 - 2009: [Profesor Invitado, miembro de staff] Curso de postgrado Red Transporte de España. COnsorcio de Universidades Españolas , U Barcelona, U Salamanca

2007 - 2010: (Tutor de tesis) Tesis Doctoral Ciencias Biologicas, José Luis Vega. Involvement of the growth factor TGF-beta 1 in the inhibition of adenosine trasnport by high extracellular levels of D-glucose in human umbilical vein endothelial cells. , Pontificia Universidad Catolica de Chile

2007 - 2010: [Tutor Tesis Doctorado] Carlos Puebla. Caracterizacion de sitios de regulacion de la expresion de SLC29A1 en endotelio humano en respuesta a glucosa. PhD en Ciencias Biologicas (m/Ciencias Fisiologicas), Facultad de Ciencias Biologicas , Pontificia Universidad Catolica de Chile

2007 - 2010: [Tutor de Tesis Doctoral] Carlos Escudero. "Papel de los receptores de adenosina A2a y A2b en la regulacion de la expresion de la oxido nitrico sintasa inducible en endotelio microvacular de la placenta de gestaciones con preclamsia" , Pontificia Universidad de Chile

2007 - 2012: [Co-Tutor Tesis Doctorado] Catalina Prieto. Arginasa-sintasa de oxido nitrico y mecanismos de regulacion funcional y de expresion de genes en endotelio humano. PhD en Ciencias Biologicas (m/Ciencias Fisiologicas), Facultad de Ciencias Biologicas , Pontificia Universidad Catolica de Chile

2007 Jul - 2007 Ago: [Tutor Post-Doctorado] Programa de Post-Doctorado. Myriam Vásquez. Cancer and hENTs expression in human fetal endothelium (Facultad de Biología) , Universitat de Barcelona, España

2007 Mar : [Examinador externo] Proyecto Tesis de Doctorado en Ciencias Biológicas. Carmen Aravena. Papel del arsénico en el cambio de pH y crecimiento celular en células colónicas. , Universidad de Antofagasta

2007 Mar - 2007 Dic: [Tutor Pre-Doctorado] Programa de formación de Pre-Doctorado. Bernardo Krause. Myography as a tool in medical research (Facultad de Medicina) (en Mar 2008 ingresó a un programa de doctorado en la PUC) , Pontificia Universidad Catolica de Chile

2007 May - 2007 Jul: [Tutor Doctorado Unidad de Investigación] Doctorado en Ciencias Biológicas. Laia Torres. hENT1 expression in lymphocites from luekemic patients. (Facultad de Biología) , Universitat de Barcelona, España

2007 May - 2007 Jun: [Clases Pregrado] Curso BIO238C Seminarios de investigación (Carrera de Medicina, Facultad de Medicina) , Pontificia Universidad Catolica de Chile

2008 - :[Tutor de Tesis Doctoral] Marcelo Farias. Señalización Intrecelular en la Reducción de la Expresion y la actividad del transportador equilibrativo de Nucleosidos 1 (hENTPapel del arsénico en el cambio ) en Endotelio de vena umbilical de embarazos con diabetes Mellitus gestacional" , Pontificia Universidad Catolica de Chile

2008 - 2009: [Clases postgrado en el extranjero] School of Biomedicine, Kings College London, PhD course , U London, UK

2008 - 2009: [Profesor Invitado, miembro de staff] Diplomado Alimentos y Salud, PUC , Pontificia Universidad Católica de Chile

2008 Ago - 2008 Sep: [Tutor Visitas de Investigación Doctorado en Ciencias]. 1 estudiante de Doctorado en Ciencias Biológicas (Universidad de Antofagasta) , Pontificia Universidad Catolica de Chile

2008 Jul - : [Examinador interno] Proyecto Tesis de Doctorado en Ciencias Médicas. NN (nombre del alumno no disponible al momento de ingresar la información).. , Pontificia Universidad Catolica de Chile

2008 Jul - 2008 Sep: [Tutor Visitas de Investigación Magister en Ciencias]. Enrique Guzman Gutierrez estudiante de Magister en Bioquímica Clínica e Inmunología (Universidad de Concepción) , Pontificia Universidad Catolica de Chile

2008 Jun - : [Examinador externo] Proyecto Tesis de Magister en Bioquímica Clínica e Inmunología. Héctor Contreras. Colesterol and its role on L-arginine transport and NO synthesis. , Universidad de Concepción

2008 Jun - 2008 Jun: [Clases Pregrado] Curso Bioética. Seminarios (Carrera de Medicina, Facultad de Medicina) , Pontificia Universidad Catolica de Chile

2008 Mar - 2009 Feb: [Tutor Post-Doctorado] Programa de formación de Post-Doctorado. Andrea Leisewitz. hENT2 and its modulation in gestational diabetes (Facultad de Medicina) , Pontificia Universidad Catolica de Chile

2008 Mar - 2012 Feb: [Co-Tutor Tesis Doctorado] Bernardo Krause. Differential vasoreactivity in the placenta from IUGR: role of epigenetic mechansisms. PhD en Ciencias Biologicas (m/Ciencias Fisiologicas), Facultad de Ciencias Biologicas. (tutor P Casanello) , Pontificia Universidad Catolica de Chile

2008 Mar - 2012 Feb: [Tutor Tesis Doctorado] Francisco Westermeier. Insulin short and long arm modulate hENT1 and hENT2 mediated adenosine transport in gestational diabetes. PhD en Ciencias Biologicas (m/Ciencias Fisiologicas), Facultad de Ciencias Biologicas , Pontificia Universidad Catolica de Chile

2008 Mar - 2012 Feb: [Co-Tutor Tesis Doctorado] Denisse Valladares. ATP and adenosine receptors in myocites development. PhD en Ciencias Bio-Médicas, Facultad de Medicina (tutor E Jaimovich) , Universidad de Chile

2008 May - 2008 Dic: [Tutor Unidad de Investigación] Ingenieria Química. Suguna Narayan. Chemistry of NO and superoxide anion interaction in gestational diabetes (University of Cincinnati, USA) , University of Cincinnati & PUC

2008 May - 2008 Jun: [Clases Pregrado] Curso BIO238C Seminarios de investigación (Carrera de Medicina, Facultad de Medicina) , Pontificia Universidad Catolica de Chile

2009 - : [Examinador interno] Bioquimico. Jovan Kuzmicic Previtali. , Pontificia Universidad de Chile

2009 - : (Examinador externo) Proyecto Tesis de Doctorado en Farmacologica. Rodrigo Lopez Muñoz. Aumento de la capacidad tripanocida de nifurtimox y benznidazol a traves de la inhibicion de la sintesis de prostaglandinas. , Universidad de Chile

2009 - 2012: [Tutor de Tesis Doctoral] Carlos Salomón. Regulación de la expresión y actividad del transportador equilibrativo de nucleósidos tipo 2 (hENT2) por insulina en endotelio microvascular de placenta humana (hPMEC) de diabetes gestacional mediante la expresión diferencial de los receptores de insulina tipo A y B. PhD en Ciencias Médicas, Facultad de Medicina , Pontificia Universidad Catolica

2009 Ene - 2009 Ene: [Tutor Visitas de Investigación Pregrado]. 1 estudiante de Química y Farmacia (Instituto Venezolano de Investigaciones Científicas, IVIC) , Pontificia Universidad Catolica de Chile

2009 Ene - 2009 Ene: [Tutor Visitas de Investigación Magister en Ciencias]. 3 estudiantes de Magister en Reproducción (Instituto Venezolano de Investigaciones Científicas, IVIC) , Pontificia Universidad Catolica de Chile

2009 Ene - 2009 Ene: [Tutor Visitas de Investigación Doctorado en Ciencias]. 1 estudiante de Doctorado en Reproducción (Instituto Venezolano de Investigaciones Científicas, IVIC) , Pontificia Universidad Catolica de Chile

2009 Ene - 2009 Ene: [Tutor Rotación Programa Especialización Obstetricia y Ginecología]. Roxana Salcedo (Panamá) , Pontificia Universidad Catolica de Chile

2009 Ene - 2009 Ene: [Tutor Rotación Programa Especialización Obstetricia y Ginecología]. Lesly Chávez (Perú) , Pontificia Universidad Catolica de Chile

2009 Ene - 2009 Mar: [Tutor Visitas de Investigación Doctorado en Ciencias]. 1 estudiante de Doctorado en Ciencias Biológicas (Universidad de Antofagasta) , Pontificia Universidad Catolica de Chile

2009 Mar - 2009 Dic: [Tutor Tesis Pregrado] Licenciatura en Biologia. Christopher Sepúlveda. Cinética de captación de D-glucosa en endotelio fetal humano expuesta a alta D-glucosa externa. Carrera de Lic en Biología, Facultad de Ciencias Biológicas , Pontificia Universidad Catolica de Chile

2009 Mar - 2009 Mar: [Tutor Rotación Programa Sub-Especialización Obstetricia y Ginecología]. Marcelo Rodríguez (Universidad de Chile) , Pontificia Universidad Catolica de Chile

2009 Mar - 2010 Feb: [Tutor Pre-Doctorado] Programa de formación de Pre-Doctorado. Miguel Jo. Myography in high and low resistant vessels from the human placenta (Facultad de Medicina). , Pontificia Universidad Catolica de Chile

2009 Mar - 2010 Feb: [Co-Tutor Tesis Magister] Natalia Celis. Intracellular pH and hENTs expression and activity in human fetal endothelium in gestational diabetes. MSc en Fisiología, Facultad de Ciencias de la Salud (tutor MA Ramírez) , Universidad de Antofagasta

2009 Mar - 2010 Feb: [Co-Tutor Tesis Magister] Jorge Muñoz. Is NHE1 countertransporter a modulator of hENT1 activity in HUVEC from gestational diabetes. MSc en Fisiología, Facultad de Ciencias de la Salud (tutor MA Ramírez) , Universidad de Antofagasta

2009 May - 2009 Jun: [Clases Pregrado] Curso BIO238 Seminarios de investigación (Carrera de Medicina, Facultad de Medicina) , Pontificia Universidad Catolica de Chile

2010 - : Editor Commentaries DOHAD Journal , DOHAD Journal

2010 - : Editor Invitado Trophoblast Research , Trophoblast Research

2010 - : (Tutor de Post-Doctorado), Dra Andrea Leiva , Pontificia Universidad Católica de Chile

2010 - : (Examinador externo) Proyecto Tesis de Doctorado en Bioquimica. Jessica Diaz Elizondo. Aldosterona en celulas monucleares de sangra periferica: papel de especies radicalarias de oxigeno y TNK-a" , Universidad de Chile

2010 - : (Revisor) Concurso Proyecto de investigación Sociedad Chilena de Endocrinologia y Diabetes. Establecimiento de tumorigenicidad de linea celular continua RCPTH (paratoroides humana) en ratones NOD/SCID7. , Sociedad Chilena de Endocrinologia y Diabetes

2010 - : [Examinador externo] Bioquimico. Francisco Minaya Retamal , Pontificia Universidad Catolica de Chile

2010 - : (Examinador externo) Proyecto Tesis de Doctor en Ciencias Medicas. Sebastian Cabrera Garcia. Descripción funcional y molecular del transporte de L-arginina y su relacion con la oxido nitrico sintasa endotelial (eNOS). Estudio en plaquetas de controles sanos y pacientes con insuficiencia renal cronica (IRC) , Universidad de Chile

2010 - 2010: (Tutor de Post-Doctorado), Lina Ruiz , Pontificia Universidad Católica de Chile

2010 - 2012: (Co-tutor de Tesis) Tesis Doctoral de Ciencias, mencion Biologia Celular y Molecular. Horacio Roa Burgos. Caracterización del transporte de adenosina y el rol de sus receptores sobre la ruta L-arginina/NO en células endoteliales de glomérulos humanos expuestas a una alta concentración extracelular de D-glucosa , Universidad Austral de Chile

2010 - 2012: (Comite Cientifico Internacional) International Federation of Placenta Associations (IFPA). Congreso mundial 2012, Japan , IFPA Japan 2012

2010 - 2013: (Tutor de Tesis) Tesis Doctoral de Ciencias Biologicas, mencion ciencias fisiologicas. Enrique Guzmán-Gutiérrez. Regulacion del efecto de insulina sobre el transporte de L-arginina por adenosina en endotelio de vena umbilical humana. , Pontificia Universidad Catolica de Chile

2010 - 2013: (Tutor de Tesis) Tesis Doctoral de Ciencias Medicas. Pablo Arroyo. Papel del Transporte de adenosina en la funcion de astrocitos en ratas con diabetes mellitus. , Pontificia Universidad Catolica de Chile

2010 - 2013 Abr: [Tutor de Post-Doctorado] Marco A Ramírez , Universidad de Antofagasta

2010 - 2013 Abr: [Tutor de Post-Doctorado] Fredy Cifuentes , Universidad de Antofagasta

2010 sept - : (Profesor invitado) Seminario de Investigación ciclo 2010. Disfuncion endotelial del micro y macro vasculatura de la placenta humana en patologias del embarazo. , Universidad de Los Andes

2010 abril - 2010 julio : [Clases Pregrado] Curso BIO238 Seminarios de investigación (Carrera de Medicina, Facultad de Medicina) , Pontificia Universidad Catolica de Chile

2010 Dic - : (Revisor) Unidad de Investigación Bio-4010. Carolina Oses Sepúlveda. Adipoquinas afectan la actividad ciliar modificando los niveles y propagación de ondas de calcio en células epiteliales del tracto reproductivo , Pontificia Universidad Católica de Chile

2010 Dic - : (Profesor invitado) Jornada de Estudio de Hipertensión durante el embarazo. Universidad del Bío-Bío , Universidad del Bío-Bío

2010 Nov - : (Examinador externo) Anteproyecto Tesis de Doctorado en Farmacología. Roger Yefi Carrasco. "Regulación de la progresion tumoral y metastasis en carcer de colon por la proteinas CK2 y caveolinas-1" , Universidad de Chile

2011 - 2012 : (Editor Invitado) revista Mediators of Inflammation , Mediators of Inflammation Journal

2011 - 2012 : (Tutor de Tesis de Pre-Grado) Katherinne Bugueño Tesis de Bioquímica. Papel de la adenosina en el efecto de insulina sobre la síntesis de óxido nítrico en células endoteliales de vena umbilical humana y en la reactividad en anillos de vena umbilical de embarazos con preeclampsia. , Universidad de Antofagasta

2011 - 2012 : (Tutor de Tesis de Pre-Grado) Manuel Santos Tesis de Bioquímica. , Pontificia Universidad Catolica de Chile

2011 - 2012 Dic: (Tutor de Tesis de Pre-Grado) Esteban Palacios Tesis de Bioquímica. Transporte de arginina en hPMEC de diabetes gestacional. , Universidad de Valparaiso

2011 Ene - : (Profesor invitado) Simposio "Papel de Adenosina en Patologías". Universidad Austral de Chile , Universidad Austral de Chile

2011 Ene - : [Examinador externo] Proyecto Tesis de Doctorado. Wallis Garrido , Universidad Austral de Chile

2011 Jun - 2011 Jun : [Examinador externo] Tesis de Doctorado. Fabián Pardo , Universidad Austral de Chile

2011 Mar - : (Profesor invitado) Curso Internacional Genómica y Proteómica en Biomedicina. Universidad Austral de Chile , Universidad Austral de Chile

2011 Mar - : Curso MDO3031 “Procesos biológicos básicos en enfermedades humanas” , Pontificia Universidad Católica de Chile

2011 Mar - 2011 Mar: [Examinador externo] Tesis PhD Michelle Anne Colomiere , University of Melbourne. Australia

2011 May - 2011 May: [Clases] Curso MDO3031 2011 Seminario "Diabetes Mellitus y Embarazo/Función Endotelial". Programa de Doctorado en Ciencias Médicas. , Pontificia Universidad Católica de Chile

2011 May - 2013 May: [Tutor de Post-Doctorado] Fabián Pardo. , Pontificia Universidad Católica de Chile

2011 Oct - 2014 Sep: [Patrocinante] Proyecto Iniciación FONDECYT Nº11110059 Andrea Leiva. , Pontificia Universidad Católica de Chile

2012 - 2013 : (Tutor de Actividad de Investigación) Camila Diez de Medina. Carrera de Medicina, PUC , Pontificia Universidad Catolica de Chile

2012 - 2015 : [Patrocinante] Proyecto Postdoctoral FONDECYT Nº3130583 Fabián Pardo. , Pontificia Universidad Catolica de Chile

2012 Jun - 2012 Jun: [Examinador externo] Tesis de Doctorado. Susana Quezada , Universidad de Chile

2012-2020 - Tutor de tesis
L Silva-Lagos - 2020 - PhD in Biomedicine U Gronignen The Netherlands Adenosine kinase and hENTs variants in gestational diabetes mellitus
R Villalobos-Labra - 2019 - PhD in Biological Sciences (m/ Physiology) PUC - Endoplasmic reticulum stress and endothelial dysfunction in pregnancy with mother with pregestational obesity
T Sáez - 2018 - PhD in Biological Sciences /m/ Physiology) - PUC - Role of fetoplacental exosomes in fetoplacental endothelial dysfunction in Gestational Diabetes Mellitus
R Salsoso - 2017 - PhD in Medical Sciences - PUC - Regulation of the L-arginina / NO-endothelial route by insulin and adenosine receptors A2A and A2B in endothelium of human umbilical vein in late onset preeclampsia
R Salsoso - 2017 - PhD in Molecular Biology, Biomedicine, Clinical Investigation - U Sevilla - Spain - Regulation of the L-arginina / NO-endothelial route by insulin and adenosine receptors A2A and A2B in endothelium of human umbilical vein in late onset preeclampsia
T Sáez - 2017 - PhD in Biomedicine - U Groningen - The Netherlands - Role of fetoplacental exosomes in fetoplacental endothelial dysfunction in Gestational Diabetes Mellitus
T Sáez - 2015 - MSc in Medical Sciences (Cellular and Molecular Biology) - U Valparáiso - Role of A1 adenosine receptors in the insulin effect on L-arginine transport in HUVECs from gestational diabetes mellitus
M Jo - 2014 - PhD in Biomedical Engineering - Auckalnd U of Technology - New Zealand - An Investigation of the dynamic response of airway smooth muscle in sensitized animal models
E Guzmán - 2013 - PhD in Neurobiology & Pharmacology - UC - La regulación del transporte de L-arginina vía hCAT-1 por insulina involucra activación diferencial de los subtipos A y B de receptores de insulina y receptores de adenosina en HUVEC
E Guzmán - 2013 - PhD in Biological Sciences /m/ Physiology) - UC - La regulación del transporte de L-arginina vía hCAT-1 por insulina involucra activación diferencial de los subtipos A y B de receptores de insulina y receptores de adenosina en HUVEC.
C Salomón - 2013 - PhD in Medical Sciences - UC - Regulation of the expression and activity of the type 2 nucleoside equilibrium transporter by insulin in the microvascular endothelium of the human placenta of gestational diabetes by means of the differential expression of type A and B insulin receptors
F Westermeier - 2012 - PhD in Biological Sciences /m/ Physiology) - UC -Differential regulation on hENT1 expression and activity by insulin receptor isoforms A and B in HUVEC from gestational diabetic pregnancies


Difusión y Transferencia


Research Grant(s) (current)

FONDECYT 1190316 (Principal investigator (PI)) (2019-4/2023) Characterization of "gestational diabesity" as a pregnancy metabolic condition causing micro and macrovascular fetoplacental endothelial dysfunction via mechanisms that are different to those described for gestational diabetes or maternal obesity (w/ J Gutiérrez (USS), A Leiva (PUC)).

FONDECYT 1190250 (Co-investigator (CoI)) (2019-4/2023) Maternal supraphysiological hypercholesterolemia in human pregnancy: contribution of lipoproteins and exosomes to vascular dysfunction of the mother and offspring at birth and later in childhood (w/ A Leiva (PI), J Carvajal, M Farías, G Martínez, C Carvajal (PUC), J Gutiérrez (USS)).

FAPESP Brazil (PI in Chile, member of the International Team - process number 2016/ 01743-5) (2018-2022) Prospective cohort study of the triad "gestational hyperglycemia, specific gestational urinary incontinence and gestational hyperglycemic myopathy" as predictor for Urinary Incontinence and Pelvic Floor Dysfunction 6-12 months after delivery; and translational research of latex biodevice with steam cells for muscle regeneration after delivery in diabetic rats (w/M Rudge (PI), UNESP (Brazil)).

FONDECYT 1180935 (CoI) (2018-3/2022) Role of RECK in preeclampsia development: a key regulator of cytotrophoblast invasiveness and spiral arteries remodelling (w/ J Gutiérrez (USS) (PI), A Leiva, M Farías (PUC)).

FAPESP Brazil (PI in Chile) (2017-2020). Comparação da qualidade sexual de gestantes e da incontinência urinária específica da gestação entre mulheres brasileiras e chilenas (w/M Rudge, MA Pascon, S Vega, UNESP (Brazil)).

UMCG RUG Sandwich PhD program/2017 U Groningen, University Medical Center Groningen (PI in Chile) (3/2017- 3/2019). hENT expression is modulated by epigenetics in fetoplacental endothelium from gestational diabetes mellitus (w/ M Faas, T Plösch (The Netherlands)).

IBTech AUT PhDFOR 2019 (PI in Chile) (12/2019-11/2023). Institute of Biomedical Technology, Auckland University of Technology cell bases of airways reactivity to a non-invasive device (w/student tbd (PUC, AUT), A Al-Jumaily (PI in New Zealand), New Zealand).

FONDECYT 1150377 (Principal investigator (PI)) (2015-3/2019) Role of insulin receptors and adenosine receptors in prevention of fetoplacental endothelial dysfunction by insulin in women with gestational diabetes mellitus. (w/A Leiva, M Farías (PUC), J Gutiérrez (U San Sebastián)).

FONDECYT 1150344 (Co-investigator (CoI)) (2015-3/2019) Involvement of PCSK9 in ‘human maternal supraphysiological hypercholesterolemia’. Effects on placental cholesterol traffic and function of neonatal lipoproteins. (w/ A Leiva (PI), J Gutiérrez (U San Sebastián)).

CONICYT Postdoctoral 3160194 (SR) (11/2015-10/2018). Role of the axis Mg2+/exosomes/adenosine in reversing the human fetoplacental microvascular endothelial dysfunction in early-onset preeclampsia. (w/I Chiarello (PUC)).

FONDECYT Initiation in Research Competition 11150083 (SR) (2015-2018). Excessive maternal gestational weight gain reduces the vascular endothelium-smooth muscle functional interaction involving endothelin-1 and nitric oxide in the human placenta (w/ F Pardo (PUC)).

IBTech AUT PhDFOR 2017 (PI in Chile) (1/2017-12/2021). Institute of Biomedical Technology, Auckland University of Technology Cell bases of airways reactivity to a non-invasive device (w/student tbd (PUC, AUT), A Al-Jumaily (PI in New Zealand), New Zealand)

UMCG RUG Sandwich PhD program/2015 (PI in Chile) (5/2015-5/2017). U Groningen, University Medical Center Groningen. Exosomes role in gestational diabetes-associated dysfunction of the fetoplacental vascular endothelium (w/ T Sáez (PUC), M Faas (The Netherlands)).

Dirección de Investigación U San Sebastián (CoI) (11/2015-11/2017). Role of RECK in the development of human preeclampsia as regulator of cytotrophoblast invasiveness and endovascular differentiation (w/ J Gutiérrez (USS), A Leiva (PUC)).

EXPLORA Conicyt 2010-2012 Science Club at preschool. Four months training in a professional laboratory. Teaching pairs at partners schools.

CONICYT Special program 2014 Science Club at preschool. Four months training in a professional laboratory. Teaching pairs at other 12 cities in Chile and 6 in Argentina, Brazil, Peru, Bolivia, New Zalanad, Australia.

Open Lab Day. 1996-at present. Every September or October, full day with activities at the Cellular and Molecular Physiology Laboratory (CMPL), PUC.

Patent
Adenosine as modulator of insulin action in gestational diabetes (Apr 2013) (w/ E Guzmán-Gutiérrez, PUC) (In process).

ACADEMIC VISITORS TO THE CMPL (Lab) 1997-2020

1997
Professor Giovanni E Mann (King’s College London, University of London, UK)
Professor M Roser Cusó (Universidad de Sevilla, Spain)
Professor David L Yudilevich (Universidad de Chile)
Professor Fernando Toledo (Universidad del Bío-Bío, Chile)
Professor Roberto Montecinos (Rector Universidad Católica del Maule, Chile)
Professor Ennio Vivaldi (Universidad de Chile)
Professor Hilario Hernández (Rector, Universidad del Bío-Bío, Chile)
Dr Carlos Moreno (King’s College London, University of London, UK)
Dr Richard CM Siow (King’s College London, University of London, UK)
Dr Patricia Arancibia (Universidad del Bío-Bío, Chile)
Dr Lopa Leach (University of Southampton, UK)

1998
Professor Ennio Vivaldi (Universidad de Chile)
Professor James Douglas Pearson (King’s College London, U London, UK)
Professor Jeremy D Pearson (King’s College London, University of London, UK)
Profesor Roberto Montecinos (Rector Universidad Católica del Maule, Chile)
Profesor Juan P García-Huidobro (Pontificia Universidad Católica de Chile)
Professor Héctor Valdivia (University of Wisconsin, EEUU)
Professor Simon M Jarvis (School of Biomedical Sciences, University of Kent, UK)
Dr Richard CM Siow (University of Cambridge, UK)
Dr Patricia Bustos (Rossentiel Research Centre, University of Brandeis, EEUU)

1999
Professor Sir Salvador Moncada (University College, University of London, UK)
Professor Giovanni E Mann (King’s College London, University of London, UK)
Professor Jeremy D Pearson (King’s College London, University of London, UK)
Professor Carol MacLeod (University of California, EEUU)
Professor Walter N Durán (University of Medicine and Dentristry of New Jersey, EEUU)
Professor Lucilla Poston (King’s College London, University of London, UK)
Dr Richard CM Siow (University of Cambridge, UK)
Dr Hernán Flores-Rozas (University of California, EEUU)
Dr John Claxton (The Wellcome Trust, UK)
Dr Gustavo Droguet (Universidad Católica Santísima de Concepción, Chile)

2000
Professor Manuel Palacín (Universitat de Barcelona, Spain)
Professor Marçal Pastor-Anglada (Universitat de Barcelona, Spain)
Professor Janice Marshall (University of Birmingham, UK)
Professor Sonia Torres (Universidad Central de Venezuela, Caracas, Venezuela)
Professor Carol MacLeod (University of California, EEUU)
Professor Juan Bacigalupo (Universidad de Chile)
Professor Rosa Devés (Universidad de Chile)
Dr Richard CM Siow (University of Cambridge, UK)

2001
Professor Marçal Pastor-Anglada (Universitat de Barcelona, Spain)
Professor Stephen Baldwin (University of Leeds, UK)
Professor Simon Jarvis (U Kent at Canterbury, UK)
Professor Jordi Molgó (Institut Federatif de Neurobiologie Alfred Fessard, France)
Professor David Apps (U Edinburgh, Scotland)
Professor Octavio Monasterio (Universidad de Chile)
Professor Raúl Godoy (Universidad de Chile)
Professor José Arteaga (Universidad del Bío-Bío, Chile)
Professor Fernando Toledo (Universidad del Bío-Bío, Chile)
Professor Juan Bacigalupo (Universidad de Chile)
Professor Ramón Latorre (CECS Valdivia, Chile)
Professor Francisco Sepúlveda (CECS Valdivia, Chile)
Professor Rosa Devés (Universidad de Chile)
Professor Juan Carlos Vera (Universidad de Concepción, Chile)
Professor Felipe Sierra (Universidad de Chile)
Professor Juan Reyes (Universidad de Católica de Valparaíso, Chile)
Dr Pablo Cid (Universidad de Chile)
Dr Felipe Barros (CECS Valdivia, Chile)
Dr Rodolfo Medina (Guy´s Hospital, London, UK)

2002
Professor Jorge Figueroa (Wake Forest University, USA)
Professor Janice Marshall (U Birmingham, UK)
Professor Anibal Llanos (Universidad de Chile)
Professor Jeremy D Pearson (King’s College London, University of London, UK)
Professor Oscar Fuentes (Universidad de Concepción, Chile)
Dr Richard Siow (King’s College London, University of London, UK)
Dr Yasenka Barrios (Universidad de Valparaíso, Chile)
Dr Mimi Siow (Writers Publishing, UK)
Dr Juan Alarcón (Universidad de Concepción, Chile)
Dr Claudio Aguayo (Universidad de Concepción, Chile)
Dr José Manuel González (Universidad Miguel Hernández, Spain)

2003
Professor Jeremy D Pearson (King’s College London, University of London, UK)
Professor Peter Gluckman (Auckland University of Technology, New Zealand)
Professor Lucilla Poston (University of London, UK)
Professor Anibal Llanos (Universidad de Chile)
Professor Mark Hanson (University of Southampton, UK)
Professor Jorge P Figueroa (Wake Forest University, USA)
Professor Walter Durán (University of Medicine and Dentistry of New Jersey, USA)
Professor Mauricio Boric (Pontificia Universidad Católica de Chile)
Professor Hilario Hernández (Rector, Universidad del Bío-Bío, Chile)
Dr Carlos Escudero (Universidad Central del Ecuador, Ecuador)

2004
Professor Sue Duckles (University of California at Irvine, EEUU)
Professor Estela Bevilaqua (Universidad de São Paulo, Brazil)
Professor Marco Antonio Zago (Universidad de São Paulo, Brazil)
Dr Liliana Lamperti (Universidad de Concepción, Chile)
Dr Jorge Roa (Universidad de Concepción, Chile)
Dr Patricio Chandía (Universidad del Bío-Bío, Chile)
Dr Adelia Amarante (Universidad de São Paulo, Brazil)
Dr Sonia Gagioti (Universidad de São Paulo, Brazil)
Dr David Sugden (King’s College London, University of London, UK)
Dr Juan Pablo García Huidobro-Toro (Pontificia Universidad Católica de Chile)

2005
Professor Gregory Rice (The Baker Medical Research Institute, Melbourne, Australia)
Professor Leslie Myatt (University of Cincinatti, EEUU)
Professor David Eisner (University of Cambridge, UK)
Professor Marçal Pastor-Anglada (Universitat de Barcelona, Spain)
Professor Gernot Desoye (Medical University of Graz, Austria)
Professor Rolph Kinne (Max Planck Institute for Molecular Physiology, Germany)
Dr Patricio Chandía (Universidad del Bío-Bío, Chile)

2006
Professor Gregory Rice (The Baker Medical Research Institute, Melbourne, Australia)
Professor Leslie Myatt (University of Cincinatti, EEUU)
Professor Alex Reuhle (University of Denver, USA)
Professor Sue Duckles (University of California at Irvine, EEUU)

2007
Professor Jaume Raventós (Universitat de Barcelona, Spain)
Professor Marçal Pastor-Anglada (Universitat de Barcelona, Spain)
Professor Jeremy D Pearson (King’s College London, University of London, UK)
Professor Leslie Myatt (University of Cincinnati, USA)
Professor Gregory Rice (University of Melbourne, Australia)
Dr Myriam Molina (Universitat de Barcelona, Spain)

2008
Professor Marçal Pastor-Anglada (Universitat de Barcelona, Spain)
Professor Gregory Rice (University of Melbourne, Australia)
Professor Susan Wray (University of Cambridge, UK)

2009
Professor Robert Waterland (Baylor College of Medicine Houston, EEUU)
Professor Gernot Desoye (Graz Medical University, Austria)
Professor Alicia Jawerbaum (Universidad de Buenos Aires, Argentina)
Professor David Barker (EEUU)
Professor Marçal Pastor-Anglada (Universitat de Barcelona, Spain)
Professor Colin Sibley (University of Manchester, UK)
Professor Jeremy D Pearson (King’s College London, University of London, UK)
Professor Leslie Myatt (University of Texas, San Antonio, EEUU)
Professor Peter Nathaniels (University of Texas, San Antonio, EEUU)
Professor Lucila Poston (University of London, UK)
Professor Gregory Rice (Baker Research Institute, University of Melbourne, Australia)
Professor Reinaldo Marín (IVIC, Venezuela)
Professor Estela Bevilacqua (Universidad de São Paulo, Brazil)

2010
Profesor Alicia Jawerbaum (Universidad de Buenos Aires, Argentina)
Professor Gernot Desoye (Graz Medical University, Austria)
Professor Estela Bevilacqua (Universidad de São Paulo, Brazil)
Professor Reinaldo Marín (IVIC, Venezuela)
Professor Gregory Rice (Baker Research Institute, University of Melbourne, Australia)
Professor Marçal Pastor-Anglada (Universitat de Barcelona, Spain)
Professor Carmen Vázquez (Universidad de Sevilla, Spain)
Dr Alfonso Mate (Universidad de Sevilla, Spain)

2011
Professor Gregory Rice (Baker Research Institute, University of Melbourne, Australia)
Professor Ahmed Al-Jumaily (Auckland University of Technology. New Zealand)
Professor Richard Garrat (Universidad de São Paulo, Brazil)
Professor Carmen Vázquez (Universidad de Sevilla, Spain)
Professor Gregory Rice (University of Queensland, Australia)
Professor Murray Mitchel (University of Queensland, Australia)
Professor Igor Feoktistov (Vanderbilt U, USA)
Dr Sonia Zambrano (Universidad de Sevilla, Spain)
Dr María Ruiz (Universidad de Sevilla, Spain)
Dr Elena León (Universidad de Sevilla, Spain)
Dr Alfonso Mate (Universidad de Sevilla, Spain)

2012
Professor Colin Sibley (University of Manchester, UK)
Professor Chris Hawley (Auckland University of Technology, New Zealand)
Professor Fernando Toledo (Universidad del Bío-Bío, Chile)
Professor Carmen Vázquez (Universidad de Sevilla, Spain)
Professor Alicia Jawerbaum (Universidad de Buenos Aires, Argentina)
Professor Ingrid Fleming (Goethe University, Germany)
Professor Wulf Palinski (UCSD, EEUU)
Dr Ursula Hiden (Medical University of Graz, Austria)

2013
Professor Gernot Desoye (Medical University of Graz, Austria)
Professor Gregory Rice (University of Queensland, Australia)
Professor Carmen Vázquez (Universidad de Sevilla, Spain)
Professor Murray Mitchel (Director UQCCR, Australia)
Professor Subrata Chakrabarti (Lawson Research Institute, Canada)
Professor James Koropatnick (Lawson Research Institute, Canada)
Professor David Hill (Lawson Research Institute, Canada)
Dr Edith Arany (Lawson Research Institute, Canada)
Dr Timothy Regnault (Lawson Research Institute, Canada)
Dr Ruud Veldhuizen (Lawson Research Institute, Canada)

2014
Professor Elmer Sterken (Rector University of Groningen, The Netherlands)
Professor Alicia Jawerbaum (Universidad de Buenos Aires, Argentina)
Professor Estela Bevilacqua (Universidad de São Paulo, Brazil)
Professor Marilza Rudge (UNESP, Brazil)
Professor Iracema Calderon (UNESP, Brazil)
Professor José Carlos Peraçoli (UNESP, Brazil)
Professor Reinaldo Marín (IVIC, Venezuela)
Professor Carmen Vázquez (Universidad de Sevilla, Spain)
Professor Bertil Fredholm (Karolinska Institutet, Suecia)
Professor Ahmed Al-Jumaily (Auckland University of Technology, New Zealand)
Professor Eliana Nahás (UNESP, Brazil)
Professor Jan-Luuk Hillebrand (University of Groningen, The Netherlands)
Professor Harry van Goor (University of Groningen, The Netherlands)
Dr Daisy Salvadori (UNESP, Brazil)
Dr Titia Lely (University of Groningen, The Netherlands)
Dr Marijke Fass (University of Groningen, The Netherlands)
Dr Torsten Ploch (University of Groningen, The Netherlands)
Dr Aureo Yamada (Universidad de Campinas, Brazil)

2015
Professor Han Moshage (University of Groningen, The Netherlands)
Professor Udo Markert (University of Jena, Germany)
Professor Leslie Myatt (University of Texas San Antonio, EEUU)
Professor Gregory Rice (University of Queensland, Australia)
Professor Jens Kroll (Heidelberg U and German Cancer Research Center, Germany)
Dr Carlos Salomón (University of Queensland, Australia)
Dr Martijn Nawijn (University of Groningen, The Netherlands)
Joyce Fongers (University of Groningen, The Netherlands)

2016
Professor Han Moshage (University of Groningen, The Netherlands)
Professor Udo Markert (University of Jena, Germany)
Professor Leslie Myatt (University of Texas San Antonio, EEUU)
Professor Gregory Rice (University of Queensland, Australia)
Professor Jens Kroll (Heidelberg U and German Cancer Research Center, Germany)
Dr Carlos Salomón (University of Queensland, Australia)

2017
Dr Marijke Faas (University of Groningen, The Netherlands)
Professor Jan-Luuk Hillebrand (University of Groningen, The Netherlands)
Professor Carmen Vázquez (Universidad de Sevilla, Spain)
Dr Flavia Sacerdoti (Universidad de Buenos Aires, Argentina)
Dr Alicia Damiano (Universidad de Buenos Aires, Argentina)
Professor Alicia Jawerbaum (Universidad de Buenos Aires, Argentina)
Professor Michael Post (University of Toronto, Canada)
Professor David Hill (Lawson Research Health Institute, Canada)
Dr Adriana Chicco (Universidad Del Litoral, Argentina)
Dr Yoreyelina Varayoud (Universidad Del Litoral, Argentina)
Professor Isabella Caniggia (University of Toronto, Canada)
Professor Cristina Ibarra (Universidad de Buenos Aires, Argentina)
Professor Estela Bevilacqua (Universidade Sao Paulo, Brazil)
Dr Aline Lorenzo-Ojea (Universidade Sao Paulo, Brazil)
Professor Gregory Rice (University of Queensland, Australia)
Professor Barbra De Vrijer (Western University, Canada)
Dr Edith Arani (Lawson Research Health Institute, Canada)
Dr Ccecilia Soñora (Universidad de la República, Uruguay)
Dr Stacy Zamudio (Hackensack University Medical Center, USA)
Professor Nicholas Illsley (Hackensack University Medical Center, USA)
Dr Nathalia Portiho (Universidade Sao Paulo, Brazil)

2018
Mr Rubén Beltrán, Ambassador from Mexico in Chile
Mr Ambar Idema, Ambassador from The Netherlands in Chile
Mr Rolf Schulze, Ambassador from Germany in Chile
Dr Marijke Faas (University of Groningen, The Netherlands)
Professor Harry Van Goor (University of Groningen, The Netherlands)
Professor Carmen Vázquez (Universidad de Sevilla, Spain)
Professor Gregory Rice (University of Queensland, Australia)
Dr Carlos Salomón (University of Queensland, Australia)
Professor Jens Kroll (Heidelberg U and German Cancer Research Center, Germany)
Professor Hans-Peter Hammes (University of Heidelberg, Germany)
Professor Karen Bieback (University of Heidelberg, Germany)
Dr Gerardo García-Rivas (TecSalud, Tecnológico de Monterrey, Mexico)
Dr Leticia Elizondo-Montemayor (TecSalud, Tecnológico de Monterrey, Mexico)
Dr Omar Lozano (TecSalud, Tecnológico de Monterrey, Mexico)
Professor Ahmed Al-Jumaily (Auckland University of Technology, New Zealand)

2019
Professor Sir Salvador Moncada (University College, University of London, UK)
Professor Ahmed Al-Jumaily (Auckland University of Technology. New Zealand)
Dr Gerardo García-Rivas (TecSalud, Tecnológico de Monterrey, Mexico)
Professor Leslie Myatt (Oregon Health and Science University, USA)
Dr Tamara Sáez (University of Alberta, Canada)
Professor Udo Markert (Jena University Hospital, Germany)
Dr Carolina Motta-Mejia (University of Oxford, UK)
Professor Guillermo Torre (Rector, TecSalud, Tecnológico de Monterrey, México)
Dr Marijke Faas (University of Groningen, The Netherlands)
Dr Padma Murthi (Monash University, Australia)
Dr Raheela Khan (University of Nottingham, UK)
Dr Jane Cleal (University of Southampton, UK)
Dr Amanda Sferruzzi-Perri (University of Cambridge, UK)
Dr Angela Myatt (Oregon, USA)
Dr Carlos Salomón (University of Queensland, Australia)


Premios y Distinciones

  •   Research Visiting Professor

    UNIVERSIDADE ESTADUAL PAULISTA

    Brasil, 2014

    Research Visiting Professor

  •   Honorary Professor

    UNIVERSIDAD DE SEVILLA

    España, 2014

    Honorary Professor at US

  •   Member

    UNIVERSIDAD DE SEVILLA

    Chile, 2013

    Member of Academic Staff of PhD Physiology Program

  •   Full Professor

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Chile, 2012

    Professor

  •   Winner of the V Patenting Contest

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Chile, 2013

    Winner of the V Patenting Contest

  •   Fellow of The Physiological Society (FPhysiol)

    The Physiological Society

    Reino Unido, 2017

    Fellow (Senior) of the Society.

  •   Associate Editor

    American Society of Mechanical Engineering

    Estados Unidos, 2017

    Appointed as Associate Editor for ASME Journal of Convergence in Biomedical Engineering and Biotechnology

  •   Vice-president

    SOCIEDAD CHILENA DE CIENCIAS FISIOLOGICAS

    Chile, 2016

    Elected as Vice-President of the SCHCF (2017-2018) continued as President (2019-2020)

  •   Best Researcher

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Chile, 2016

    Best Researcher prize from Faculty of Medicine PUC

  •   Regional Editor SouthAmerica

    Current Vascular Pharmacology

    Reino Unido, 2015

    Appointed as Regional Editor for South America at Current Vascular Pharmacology

  •   Various

    Various Entities

    Chile, 2017

    2015: Appointed as Regional Editor for South America at Current Vascular Pharmacology (IF 2.966); Local Organizer Committee IFPA 2015 & Session co-chairman IFPA 2015, Brisbane (Australia); The Physiological Society (UK) senior travel grant (Physiology 2015). 2014: Research Visiting Professor, UNESP (Brazil); Honorary Professor at US (Spain); SLIMP Directory Member; Invited Lecturer & Research Visiting Professor, MUG (Austria). 2013: Member of Academic Staff of PhD Physiology Program, US (Spain); Member of Medicine Area Committee of Advanced Human Resources Formation Program CONICYT (Chile); Editorial Board Member at Global Journal of Pathology and Microbiology; Winner of the V Patenting Contest, PUC (Chile); Honorary Professor at UQCCR (Australia); Visiting Professor, RUG (The Netherlands); Research Visiting Professor, MUG (Austria). 2012: Full Professor (Professor), PUC (Chile); External Advisor at the National Commission of Accreditation (CNA-Chile) for Postgraduate Programmes (Chile); Research Visiting Professor, US (Spain).


 

Article (246)

Adenosine kinase and cardiovascular fetal programming in gestational diabetes mellitus
Oxidative stress: Normal pregnancy versus preeclampsia
Role of proteases in dysfunctional placental vascular remodelling in preeclampsia
Study protocol to investigate biomolecular muscle profile as predictors of long-term urinary incontinence in women with gestational diabetes mellitus
The activity of IKCa and BKCa channels contributes to insulin-mediated NO synthesis and vascular tone regulation in human umbilical vein
Exosomes derived from monocytes and from endothelial cells mediate monocyte and endothelial cell activation under high D-glucose conditions
Impaired signalling pathways mediated by extracellular vesicles in diabesity
Involvement of A(2B) adenosine receptors as anti-inflammatory in gestational diabesity
Involvement of Intracellular pH in Vascular Insulin Resistance
Neonates from women with pregestational maternal obesity show reduced umbilical vein endothelial response to insulin
Endoplasmic reticulum stress and development of insulin resistance in adipose, skeletal, liver, and foetoplacental tissue in diabesity
Extracellular vesicles in obesity and diabetes mellitus.
Fetoplacental endothelial exosomes modulate high D-glucose-induced endothelial dysfunction
Fetoplacental endothelial exosomes modulate high d-glucose-induced endothelial dysfunction.
Foetoplacental communication via extracellular vesicles in normal pregnancy and preeclampsia.
Foetoplacental communication via extracellular vesicles in normal pregnancy and preeclampsia.
Foetoplacental epigenetic changes associated with maternal metabolic dysfunction
Human umbilical vein endothelium-derived exosomes play a role in foetoplacental endothelial dysfunction in gestational diabetes mellitus
Human umbilical vein endothelium-derived exosomes play a role in foetoplacental endothelial dysfunction in gestational diabetes mellitus.
Human umbilical vein endothelium-derived exosomes play a role in foetoplacental endothelial dysfunction in gestational diabetes mellitus.
Insulin therapy and its consequences for the mother, foetus, and newborn in gestational diabetes mellitus
Intracellular acidification reduces L-arginine transport via system y(+)L but not via system y(+)/CATs and nitric oxide synthase activity in human umbilical vein endothelial cells
Intracellular acidification reduces L-arginine transport via system y+L but not via system y+/CATs and nitric oxide synthase activity in human umbilical vein endothelial cells
Maternal supraphysiological hypercholesterolemia associates with endothelial dysfunction of the placental microvasculature
Mechanisms of the effect of magnesium salts in preeclampsia
Mechanisms of the effect of magnesium salts in preeclampsia.
Pre-pregnancy maternal obesity associates with endoplasmic reticulum stress in human umbilical vein endothelium
Role of extracellular vesicles in glioma progression.
Role of extracellular vesicles in glioma progression.
Adenosine - from molecular mechanisms to pathophysiology
Adenosine and preeclampsia
Adenosine contribution to normal renal physiology and chronic kidney disease
Adenosine receptors: Modulators of lipid availability that are controlled by lipid levels
Akt/mTOR Role in Human Foetoplacental Vascular Insulin Resistance in Diseases of Pregnancy
Cross Talk between Adipose Tissue and Placenta in Obese and Gestational Diabetes Mellitus Pregnancies via Exosomes
Cross talk between adipose tissue and placenta in obese and gestational diabetes mellitus pregnancies via exosomes.
Insulin/adenosine axis linked signalling
Intracellular acidification increases adenosine transport in human umbilical vein endothelial cells
Maternal insulin therapy does not restore foetoplacental endothelial dysfunction in gestational diabetes mellitus
Maternal insulin therapy does not restore foetoplacental endothelial dysfunction in gestational diabetes mellitus.
Molecular implications of adenosine in obesity
Multidrug resistance in glioblastoma stem-like cells: Role of the hypoxic microenvironment and adenosine signaling
Pharmacological targeting of adenosine receptor signaling
Preeclampsia associates with RECK-dependent decrease in human trophoblasts migration and invasion
Preeclampsia associates with RECK-dependent decrease in human trophoblasts migration and invasion.
Sodium/proton exchanger isoform 1 regulates intracellular pH and cell proliferation in human ovarian cancer
A hypothesis for the role of RECK in angiogenesis
A Hypothesis for the Role of RECK in Angiogenesis.
Are NHE1 and inducible nitric oxide synthase involved in human ovarian cancer?
Dexmedetomidine protects the heart against ischemia-reperfusion injury by an endothelial eNOS/NO dependent mechanism
Insulin Induces Relaxation and Decreases Hydrogen Peroxide-Induced Vasoconstriction in Human Placental Vascular Bed in a Mechanism Mediated by Calcium-Activated Potassium Channels and L-Arginine/Nitric Oxide Pathways
Insulin Is a Key Modulator of Fetoplacental Endothelium Metabolic Disturbances in Gestational Diabetes Mellitus
Insulin receptor isoforms: an integrated view focused on gestational diabetes mellitus
Insulin receptor isoforms: an integrated view focused on gestational diabetes mellitus.
Insulin requires A(1) adenosine receptors expression to reverse gestational diabetes-increased L-arginine transport in human umbilical vein endothelium
Insulin requires A1 adenosine receptors expression to reverse gestational diabetes-increased L-arginine transport in human umbilical vein endothelium.
Intracellular and extracellular pH dynamics in the human placenta from diabetes mellitus
Modulation of intracellular ph in human ovarian cancer
Modulatory Effect of 2-(4-Hydroxyphenyl)amino-1,4-naphthoquinone on Endothelial Vasodilation in Rat Aorta
Nitric oxide and pH modulation in gynaecological cancer
Nitric oxide is a central common metabolite in vascular dysfunction associated with diseases of human pregnancy
Role for Tetrahydrobiopterin in the Fetoplacental Endothelial Dysfunction in Maternal Supraphysiological Hypercholesterolemia
Tetrahydrobiopterin Role in human umbilical vein endothelial dysfunction in maternal supraphysiological hypercholesterolemia
Tetrahydrobiopterin Role in human umbilical vein endothelial dysfunction in maternal supraphysiological hypercholesterolemia.
Cross-sectional and longitudinal lipid determination studies in pregnant women reveal an association between increased maternal LDL cholesterol concentrations and reduced human umbilical vein relaxation.
Cross-sectional and longitudinal lipid determination studies in pregnant women reveal an association between increased maternal LDL cholesterol concentrations and reduced human umbilical vein relaxation
Cross-sectional and longitudinal lipid determination studies in pregnant women reveal an association between increased maternal LDL cholesterol concentrations and reduced human umbilical vein relaxation.
Dexamethasone and rosiglitazone are sufficient and necessary for producing functional adipocytes from mesenchymal stem cells
Dexamethasone and rosiglitazone are sufficient and necessary for producing functional adipocytes from mesenchymal stem cells.
Escherichia coli Heat-Stable Enterotoxin Mediates Na+/H+ Exchanger 4 Inhibition Involving cAMP in T-84 Human Intestinal Epithelial Cells
Human supraphysiological gestational weight gain and fetoplacental vascular dysfunction.
Human supraphysiological gestational weight gain and fetoplacental vascular dysfunction
Insulin requires normal expression and signaling of insulin receptor A to reverse gestational diabetes-reduced adenosine transport in human umbilical vein endothelium
Insulin requires normal expression and signaling of insulin receptor A to reverse gestational diabetes-reduced adenosine transport in human umbilical vein endothelium.
Insulin requires normal expression and signalling of insulin receptor A to reverse gestational diabetes-reduced adenosine transport in human umbilical vein endothelium
Insulin restores L-arginine transport requiring adenosine receptors activation in umbilical vein endothelium from late-onset preeclampsia
Insulin restores L-arginine transport requiring adenosine receptors activation in umbilical vein endothelium from late-onset preeclampsia
Insulin restores L-arginine transport requiring adenosine receptors activation in umbilical vein endothelium from late-onset preeclampsia.
Insulin Reverses D-Glucose-Increased Nitric Oxide and Reactive Oxygen Species Generation in Human Umbilical Vein Endothelial Cells
Insulin reverses D-glucose–increased nitric oxide and reactive oxygen species generation in human umbilical vein endothelial cells.
Insulin therapy and fetoplacental vascular function in gestational diabetes mellitus
Insulin therapy and fetoplacental vascular function in gestational diabetes mellitus.
NHE1 promote cell proliferation in ovarian cancer: a role of hypoxia-inducible factors.
A Gestational Profile of Placental Exosomes in Maternal Plasma and Their Effects on Endothelial Cell Migration
A gestational profile of placental exosomes in maternal plasma and their effects on endothelial cell migration.
A gestational profile of placental exosomes in maternal plasma and their effects on endothelial cell migration.
Diseases of pregnancy and fetal programming: cell and molecular mechanisms.
Diseases of pregnancy and fetal programming: cell and molecular mechanisms.
Fetoplacental endothelial dysfunction in maternal hypercholesterolemia and obesity in pregnancy.
Fetoplacental endothelial dysfunction in maternal hypercholesterolemia and obesity in pregnancy.
Insulin requires normal expression and signalling of insulin receptor A to reverse gestational diabetes-reduced adenosine transport in human umbilical vein endothelium
Insulin Requires Normal Expression and Signalling of Insulin Receptor A to Reverse Gestational Diabetes-reduced Adenosine Transport in Human Umbilical Vein Endothelium
Is a low level of free thyroxine in the maternal circulation associated with altered endothelial function in gestational diabetes?
Is a low level of free thyroxine in the maternal circulation associated with altered endothelial function in gestational diabetes?
Modulation of endothelial cell migration by ER stress and insulin resistance: a role during maternal obesity?
Potential Role of A(2B) Adenosine Receptors on Proliferation/Migration of Fetal Endothelium Derived from Preeclamptic Pregnancies
Potential Role of A2B Adenosine Receptors on Proliferation/Migration of Fetal Endothelium Derived from Preeclamptic Pregnancies.
Potential role of A2B adenosine receptors on proliferation/migration of fetal endothelium derived from preeclamptic pregnancies.
Reduced L-Carnitine Transport in Aortic Endothelial Cells from Spontaneously Hypertensive Rats
Reduced L-carnitine transport in aortic endothelial cells from spontaneously hypertensive rats.
Role of insulin and adenosine in the human placenta microvascular and macrovascular endothelial cell dysfunction in gestational diabetes mellitus.
The Concentration of placenta-derived exosome in the maternal circulation increases during pregnancy and induces endothelial cell migration.
The Concentration of placenta-derived exosome in the maternal circulation increases during pregnancy and induces endothelial cell migration.
5 '-ectonucleotidase mediates multiple-drug resistance in glioblastoma multiforme cells
5'-ectonucleotidase mediates multiple-drug resistance in glioblastoma multiforme cells.
Exosomal Signaling during Hypoxia Mediates Microvascular Endothelial Cell Migration and Vasculogenesis
Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis.
Gestational diabetes mellitus and the role of adenosine in the human placental endothelium and central nervous system.
Gestational diabetes mellitus and the role of adenosine in the human placental endothelium and central nervous system.
Hypoxia-Induced Changes in the Bioactivity of Cytotrophoblast-Derived Exosomes
Hypoxia-induced changes in the bioactivity of cytotrophoblast-derived exosomes.
Maternal Hypercholesterolemia in Pregnancy Associates With Umbilical Vein Endothelial Dysfunction Role of Endothelial Nitric Oxide Synthase and Arginase II
Maternal hypercholesterolemia in pregnancy associates with umbilical vein endothelial dysfunction: role of eNOS and arginase II.
Mice Long-Term High-Fat Diet Feeding Recapitulates Human Cardiovascular Alterations: An Animal Model to Study the Early Phases of Diabetic Cardiomyopathy
Mice long-term high-fat diet feeding recapitulates human cardiovascular alterations: an animal model to study the early phases of diabetic cardiomyopathy.
Role of equilibrative adenosine transporters and adenosine receptors as modulators of the human placental endothelium in gestational diabetes mellitus
Role of equilibrative adenosine transporters and adenosine receptors as modulators of the human placental endothelium in gestational diabetes mellitus.
Role of equilibrative adenosine transporters and adenosine receptors as modulators of the human placental endothelium in gestational diabetes mellitus.
[Basic science in Obstetrics and Gynecology: a need.]. Ciencia básica en Obstetricia y Ginecología: una necesidad.
[Basic science in Obstetrics and Gynecology: a need.]. Ciencia básica en Obstetricia y Ginecología: una necesidad.
Adenosine plasma levels in the fetoplacental circulation in preeclampsia.
Gestational Diabetes Reduces Adenosine Transport in Human Placental Microvascular Endothelium, an Effect Reversed by Insulin
Gestational diabetes reduces adenosine transport in human placental microvascular endothelium, an effect reversed by insulin.
Insulin-Increased L-Arginine Transport Requires A(2A) Adenosine Receptors Activation in Human Umbilical Vein Endothelium
Insulin-increased L-arginine transport requires A2A adenosine receptors activation in human umbilical vein endothelium.
New therapeutic approaches to treating hypertension in pregnancy
Potential Role of Sodium-Proton Exchangers in the Low Concentration Arsenic Trioxide-Increased Intracellular pH and Cell Proliferation
Potential role of sodium-proton exchangers in the low concentration arsenic trioxide-increased intracellular pH and cell proliferation.
Role of arginase-2 and eNOS in the differential vascular reactivity and hypoxia-induced endothelial response in umbilical arteries and veins
Role of arginase-2 and eNOS in the differential vascular reactivity and hypoxia-induced endothelial response in umbilical arteries and veins.
Differential placental macrovascular and microvascular endothelial dysfunction in gestational diabetes.
Fetoplacental vascular endothelial dysfunction as an early phenomenon in the programming of human adult diseases in subjects born from gestational diabetes mellitus or obesity in pregnancy.
Functional link between adenosine and insulin: a hypothesis for feto-placental vascular endothelial dysfunction in gestational diabetes.
Functional Link Between Adenosine and Insulin: A Hypothesis for Fetoplacental Vascular Endothelial Dysfunction in Gestational Diabetes
High D-glucose reduces SLC29A1 promoter activity and adenosine transport involving specific protein 1 in human umbilical vein endothelium.
Hypoxia-reduced nitric oxide synthase activity is partially explained by higher arginase-2 activity and cellular redistribution in human umbilical vein endothelium
Hypoxia-reduced nitric oxide synthase activity is partially explained by higher arginase-2 activity and cellular redistribution in human umbilical vein endothelium.
Increased expression of the multidrug resistance-associated protein 1 (MRP1) in kidney glomeruli of streptozotocin-induced diabetic rats
Insulin Restores Gestational Diabetes Mellitus Reduced Adenosine Transport Involving Differential Expression of Insulin Receptor Isoforms in Human Umbilical Vein Endothelium
Insulin restores gestational diabetes mellitus-reduced adenosine transport involving differential expression of insulin receptor isoforms in human umbilical vein endothelium.
Insulin restores gestational diabetes mellitus-reduced adenosine transport involving differential expression of insulin receptor isoforms in human umbilical vein endothelium.
Insulin-Stimulated L-Arginine Transport Requires SLC7A1 Gene Expression and Is Associated With Human Umbilical Vein Relaxation
Insulin-stimulated L-arginine transport requires SLC7A1 gene expression and is associated with human umbilical vein relaxation.
Placenta: Preface
Preface.
Review: Differential placental macrovascular and microvascular endothelial dysfunction in gestational diabetes
The activity of the multidrug resistance-associated protein 1 (MRP1) is increased in kidney glomeruli of diabetic rats.
Congreso mundial de la Federación Internacional de Asociaciones de Placenta, IFPA Chile 2010.
Differential expression of functional nucleoside transporters in non-differentiated and differentiated human endothelial progenitor cells
Differential expression of functional nucleoside transporters in non-differentiated and differentiated human endothelial progenitor cells.
IFPA Meeting 2009 workshops report.
Nitric oxide reduces SLC29A1 promoter activity and adenosine transport involving transcription factor complex hCHOP-C/EBP alpha in human umbilical vein endothelial cells from gestational diabetes
Nitric oxide reduces SLC29A1 promoter activity and adenosine transport involving transcription factor complex hCHOP-C/EBPα in human umbilical vein endothelial cells from gestational diabetes.
Do adenosine receptors offer new therapeutic options for diabetic nephropathy?
A Role for Insulin on L-Arginine Transport in Fetal Endothelial Dysfunction in Hyperglycaemia
A Role for insulin on L-arginine transport in fetal endothelial dysfunction in hyperglycaemia.
Adenosine mediates transforming growth factor-beta 1 release in kidney glomeruli of diabetic rats
Adenosine mediates transforming growth factor-beta 1 release in kidney glomeruli of diabetic rats.
Brain natriuretic peptide (BNP) produced by the human chorioamnion may mediate pregnancy myometrial quiescence.
Congreso mundial de la Federación Internacional de Asociaciones de Placenta, IFPA Chile 2010.
Control of the vasculature: pharmacological targets in vascular disease.
Epigenetics: New Concepts of Old Phenomena in Vascular Physiology
Epigenetics: new concepts of old phenomena in vascular physiology.
Equilibrative nucleoside transporters in fetal endothelial dysfunction in diabetes mellitus and hyperglycaemia.
Potential cell signalling mechanisms involved in differential placental angiogenesis in mild and severe pre-eclampsia.
Reduced L-Arginine Transport and Nitric Oxide Synthesis in Human Umbilical Vein Endothelial Cells from Intrauterine Growth Restriction Pregnancies is Not Further Altered by Hypoxia
Reduced L-arginine transport and nitric oxide synthesis in human umbilical vein endothelial cells from intrauterine growth restriction pregnancies is not further altered by hypoxia.
TGF-beta 1 inhibits expression and activity of hENT1 in a nitric oxide-dependent manner in human umbilical vein endothelium
TGF-ß1 inhibits expression and activity of hENT1 in a nitric oxide-dependent manner in human umbilical vein endothelium.
A hypothesis for preeclampsia: adenosine and inducible nitric oxide synthase in human placental microvascular endothelium.
Adenosine A(2B) receptor mediates an increase on VEGF-A production in rat kidney glomeruli
Adenosine A2B receptor mediates an increase on VEGF-A production in rat kidney glomeruli.
High D-Glucose reduces SLC29A1 promoter activity and adenosine transport involving specific protein 1 in human umbilical vein endothelium
Human equilibrative nucleoside transporters 1 and 2 are differentially modulated by A2B adenosine receptors in placenta microvascular endothelial cells from preeclampsia.
Human equilibrative nucleoside transporters 1 and 2 may be differentially modulated by A(2B) adenosine receptors in placenta microvascular endothelial cells from pre-eclampsia
Specific protein 1 Involvement in high D-glucose reduced SLC29A1 promoter activity and adenosine transport in human umbilical vein endothelium.
D-Glucose stimulation of L-arginine transport and nitric oxicle synthesis results from activation of mitogen-activated protein kinases p42/44 and smad2 requiring functional type II TGF-beta receptors in human umbilical vein endothelium
D-glucose stimulation of L-arginine transport and nitric oxide synthesis results from activation of mitogen-activated protein kinases p42/44 and Smad2 requiring functional type II TGF-? receptors in human umbilical vein endothelium
D-glucose stimulation of L-arginine transport and nitric oxide synthesis results from activation of mitogen-activated protein kinases p42/44 and Smad2 requiring functional type II TGF-beta receptors in human umbilical vein endothelium.
Equilibrative nucleoside (ENTs) and cationic amino acid (CATs) transporters: implications in foetal endothelial dysfunction in human pregnancy diseases.
Reduced placental flux in severe pre-eclampsia: is adenosine involved in this phenomenon?
Reduced placental flux in severe pre-eclampsia: is adenosine involved in this phenomenon?
Gestational diabetes and the adenosine/L-arginine/nitric oxide (ALANO) pathway in human umbilical vein endothelium.
Insulin restores glucose inhibition of adenosine transport by increasing the expression and activity of the equilibrative nucleoside transporter 2 in human umbilical vein endothelium
Insulin restores glucose inhibition of adenosine transport by increasing the expression and activity of the equilibrative nucleoside transporter 2 in human umbilical vein endothelium.
Nitric oxide reduces adenosine transporter ENT1 gene (SLC29A1) promoter activity in human fetal endothelium from gestational diabetes.
Nitric oxide reduces adenosine transporter ENT1 gene (SLC29A1) promoter activity in human fetal endotheliurn from gestational diabetes
Role of transforming growth factor β1 as modulator of endothelial L-arginine/NO signaling pathway.
Role of transforming growth factor β1 as modulator of endothelial L-arginine/NO signaling pathway.
Equilibrative nucleoside transporter 2 is expressed in human umbilical vein endothelium, but is not involved in the inhibition of adenosine transport induced by hyperglycaemia.
Equilibrative nucleoside transporter 1 expression is downregulated by hypoxia in human umbilical vein endothelium
Equilibrative nucleoside transporter 1 expression is downregulated by hypoxia in human umbilical vein endothelium.
Equilibrative nucleoside transporter 2 is expressed in human umbilical vein endothelium, but is not involved in the inhibition of adenosine transport induced by hyperglycaemia
Cell signalling-mediating insulin increase of mRNA expression for cationic amino acid transporters-1 and -2 and membrane hyperpolarization in human umbilical vein endothelial cells.
Cell signalling-mediating insulin increase of mRNA expression for cationic amino acid transporters-1 and-2 and membrane hyperpolarization in human umbilical vein endothelial cells
Role of adenosine transport in gestational diabetes-induced L-arginine transport and nitric oxide synthesis in human umbilical vein endothelium
Role of adenosine transport in gestational diabetes-induced L-arginine transport and nitric oxide synthesis in human umbilical vein endothelium.
Hyperglycaemia inhibits thymidine incorporation and cell growth via protein kinase C, mitogen-activated protein kinases and nitric oxide in human umbilical vein endothelium
Hyperglycaemia inhibits thymidine incorporation and cell growth via protein kinase C, mitogen-activated protein kinases and nitric oxide in human umbilical vein endothelium.
Nitric oxide synthesis requires activity of the cationic and neutral amino acid transport system y(+)L in human umbilical vein endothelium
Nitric oxide synthesis requires activity of the cationic and neutral amino acid transport system y+L in human umbilical vein endothelium.
Rapid stimulation of L-arginine transport by D-glucose involves P42/44(mapk) and nitric oxide in human umbilical vein endothelium
Rapid stimulation of L-arginine transport by D-glucose involves p42/44(mapk) and nitric oxide in human umbilical vein endothelium.
Regulation of amino acid and glucose transporters in endothelial and smooth muscle cells.
Early activation of the p42/p44(MAPK) pathway mediates adenosine-induced nitric oxide production in human endothelial cells: a novel calcium-insensitive mechanism
Early activation of the p42/p44MAPK pathway mediates adenosine-induced nitric oxide production in human endothelial cells: a novel calcium-insensitive mechanism.
Inhibition of nitrobenzylthioinosine-sensitive adenosine transport by elevated D-glucose involves activation of P-2Y2 purinoceptors in human umbilical vein endothelial cells
Inhibition of nitrobenzylthioinosine-sensitive adenosine transport by elevated D-glucose involves activation of P2Y2 purinoceptors in human umbilical vein endothelial cells.
Intrauterine growth retardation is associated with reduced activity and expression of the cationic amino acid transport systems y(+)/hCAT-1 and y(+)/hCAT-2B and lower activity of nitric oxide synthase in human umbilical vein endothelial cells
Intrauterine growth retardation is associated with reduced activity and expression of the cationic amino acid transport systems y+/hCAT-1 and y+/hCAT-2B and lower activity of nitric oxide synthase in human umbilical vein endothelial cells.
Modulation of adenosine transport by insulin in human umbilical artery smooth muscle cells from normal or gestational diabetic pregnancies
Modulation of adenosine transport by insulin in human umbilical artery smooth muscle cells from normal or gestational diabetic pregnancies.
[Tumorogenesis and mdm2 protein].
Nitric oxide, cGMP and cAMP modulate nitrobenzylthioinosine-sensitive adenosine transport in human umbilical artery smooth muscle cells from subjects with gestational diabetes
Nitric oxide, cGMP and cAMP modulate nitrobenzylthioinosine-sensitive adenosine transport in human umbilical artery smooth muscle cells from subjects with gestational diabetes.
Regulation of adenosine transport by D-glucose in human fetal endothelial cells: involvement of nitric oxide, protein kinase C and mitogen-activated protein kinase
Regulation of adenosine transport by D-glucose in human fetal endothelial cells: involvement of nitric oxide, protein kinase C and mitogen-activated protein kinase.
Elevated D-glucose induces insulin insensitivity in human umbilical endothelial cells isolated from gestational diabetic pregnancies
Elevated D-glucose induces insulin insensitivity in human umbilical endothelial cells isolated from gestational diabetic pregnancies.
Activation of A 2-purinoceptors by adenosine stimulates L-arginine transport (system y +) and nitric oxide synthesis in human fetal endothelial cells
Activation of A2-purinoceptors by adenosine stimulates L-arginine transport (system y+) and nitric oxide synthesis in human fetal endothelial cells.
Diabetes and insulin-induced stimulation of L-arginine transport and nitric oxide synthesis in rabbit isolated gastric glands
Diabetes and insulin-induced stimulation of L-arginine transport and nitric oxide synthesis in rabbit isolated gastric glands.
Diabetes-induced stimulation of L-arginine transport and nitric oxide synthesis in rabbit isolated gastric glands.
Dysfunction of the endothelial nitric oxide signalling pathway in diabetes and hyperglycaemia
Dysfunction of the endothelial nitric oxide signalling pathway in diabetes and hyperglycaemia.
Activation of L-arginine transport (system y +) and nitric oxide synthase by elevated glucose and insulin in human endothelial cells
Activation of L-arginine transport (system y+) and nitric oxide synthase by elevated glucose and insulin in human endothelial cells.
Bovine adrenal endothelial cells express nucleoside transporters nonregulated by protein kinases A and C.
Bovine adrenal endothelial cells express transporters nonregulated by protein kinases A and C
Diabetes-induced activation of system y+ and nitric oxide synthase in human endothelial cells: association with membrane hyperpolarization.
Diabetes-induced activation of system y+ and nitric oxide synthase in human endothelial cells: association with membrane hyperpolarization.
Transport and metabolism of adenosine in diabetic human placenta.
Transport and metabolism of adenosine in diabetic human placenta.
Adenosine transport in cultured human endothelial umbilical vein endothelial cells is reduced in diabetes.
Adenosine transport in cultured human umbilical vein endothelial cells is reduced in diabetes.
L-Leucine and L-phenylalanine transport through the basolateral membrane in isolated oxyntic glands.
L-Leucine and L-phenylalanine transport through the basolateral membrane in isolated oxyntic glands.
Uptake of L-leucine and L-phenylalanine across the basolateral cell surface in isolated oxyntic glands.
Kinetics and specificity of L-alanine transport across the basolateral cell surface in isolated oxyntic glands.
Kinetics of the L-alanine transport through the basolateral membrane in isolated oxyntic glands.
Luminal uptake of amino acids in rat stomach.
Luminal uptake of amino acids in rat stomach.
Cholinergic receptors in toad skin (Pleurodema thaul). Role of calcium
Cholinergic receptors in toad skin (Pleurodema thaul). Role of calcium.
Uptake and absorption of L-amino acids through the gastric epithelia in anaesthetized dogs.

Abstract (129)

EFFECT OF MGSO(4) ON PROTEIN EXPRESSION AND EXOSOMES RELEASE FROM HUMAN PLACENTAL MICROVASCULAR ENDOTHELIAL CELLS FROM LATE-ONSET PREECLAMPSIA
ELEVETED MATERNAL LIPID LEVEL INCREASES CHOLESTEROL EFFLUX TO HDL IN HUMAN TROPHOBLAST BUT NOT IN PLACENTAL MICROVASCULAR ENDOTHELIAL CELLS
ENDOPLASMIC RETICULUM STRESS IN HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS FROM PRE-GESTATIONAL MATERNAL OBESITY
EXCESSIVE GESTATIONAL WEIGHT GAIN REDUCES THE RESPONSE TO VASOACTIVE MOLECULES IN HUMAN FETOPLACENTAL MICROVESSELS
HIGH D-GLUCOSE-INCREASED NITRIC OXIDE GENERATION LEADS TO HIGHER DEIODINASE 3 MRNA LEVEL IN HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS
HUMAN MATERNAL SUPRAPHYSIOLOGICAL HYPERCHOLESTEROLEMIA INCREASES THE EFFLUX OF CHOLESTEROL FROM PLACENTAL TROPHOBLAST AND MICROVASCULAR ENDOTHELIAL CELLS
HUMAN MATERNAL SUPRAPHYSIOLOGICAL HYPERCHOLESTEROLEMIA LEADS TO ENDOTHELIAL DYSFUNCTION OF THE PLACENTAL MICROVASCULATURE
INCREASED MATERNAL LIPID LEVELS REDUCE THE PLACENTAL HDL AND LDL CHOLESTEROL UPTAKE IN HUMAN TROPHOBLAST
INSULIN RECOVERS ENDOTHELIAL DYSFUNCTION REQUIRING An ADENOSINE RECEPTOR ACTIVATION IN HUMAN UMBILICAL VEIN ENDOTHELIUM FROM LATE-ONSET PREECLAMPSIA
INSULIN THERAPY DOES NOT REVERSE GESTATIONAL DIABETES-ASSOCIATED FOETOPLACENTAL ENDOTHELIAL DYSFUNCTION
INSULIN THERAPY FAILS TO REVERSE THE HUMAN FOETOPLACENTAL ENDOTHELIAL DYSFUNCTION IN GESTATIONAL DIABETES MELLITUS
INSULIN THERAPY RESTORES THE EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1 EXPRESSION IN HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS FROM GESTATIONAL DIABETES MELLITUS
MATERNAL OBESITY ASSOCIATES WITH FOETOPLACENTAL VASCULAR DYSFUNCTION INVOLVING ENDOPLASMIC RETICULUM STRESS AND ALTERED INSULIN VASCULAR REACTIVITY
MATERNAL SUPRAPHYSIOLOGICAL DYSLIPIDEMIA IN PREGNANCY WORSE VASCULAR RESPONSE OF UMBILICAL VEIN RINGS FROM GESTATIONAL DIABETES MELLITUS
MODULATION OF THE PLACENTAL HDL AND LDL CHOLESTEROL UPTAKE BY THE MATERNAL LIPIDS LEVEL IN HUMAN TROPHOBLAST
NEONATAL HIGH-DENSITY LIPOPROTEIN FROM PREGNANCIES WITH MATERNAL SUPRAPHYSIOLOGICAL HYPERCHOLESTEROLEMIA IMPAIRS NITRIC OXIDE SYNTHASE ACTIVITY IN HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS
NHE1 MODULATES INTRACELLULAR PH AND CELL PROLIFERATION IN HUMAN OVARIAN CANCER
PREVALENCE OF MATERNAL SUPRAPHYSIOLOGICAL DYSLIPIDEMIA IN A GROUP OF CHILEAN PREGNANT WOMEN WITH GESTATIONAL DIABETES MELLITUS
RECIC EXPRESSION IS INDUCED IN PLACENTAS FROM PREECLAMPSIA AND REDUCES MIGRATION, INVASION, AND ENDOVASCULAR REMODELLING OF FIRST TRIMESTER HUMAN TROPHOBLAST
SODIUM/PROTON EXCHANGER SUBTYPE 1 REGULATES INTRACELLULAR PH IN HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS FROM GESTATIONAL DIABETES MELLITUS
Activation of Transcriptional Response Elements of Endoplasmic Reticulum Stress in Human Umbilical Vein Endothelial Cells from Maternal Obesity.
EFFECT OF HIGH GLUCOSE EXPOSURE ON ENDOTHELIAL FUNCTION MEDIATED BY FETO-PLACENTAL ENDOTHELIAL EXOSOMES
Endothelial Dysfunction and Reduced Insulin Response in Umbilical Vein from the Offspring of Maternal Obesity Pregnancies.
GESTATIONAL DIABETES AND FETO-PLACENTAL ENDOTHELIAL DYSFUNCTION: ROLE OF EXOSOMES FROM HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS ON L-ARGININE/NO SIGNALLING PATHWAY
GESTATIONAL DIABETES DECREASES TERMINAL VILLOUS VASCULATURE IN HUMAN PLACENTA
GESTATIONAL DIABETES DIFFERENTIALLY MODIFIES THYROID HORMONE TRANSPORTER EXPRESSION IN HUMAN PLACENTAL COTYLEDON
HIGH FAT DIET IN MICE INDUCES ENDOPLASMIC RETICULUM STRESS IN LIVERS OF THEIR OFFSPRING
INSULIN RECEPTOR A AND A(1) ADENOSINE RECEPTORS EXPRESSION ARE REQUIRED TO RESTORE HUMAN FETOPLACENTAL ENDOTHELIAL FUNCTION IN GESTATIONAL DIABETES MELLITUS
INSULIN RESTORES L-ARGININE AND ADENOSINE TRANSPORT REQUIRING ADENOSINE RECEPTORS ESPRESSION IN HUMAN FETOPLACENTAL ENDOTHELIUM FROM GESTATIONAL DIABETES MELLITUS
INSULIN-INCREASED ENDOTHELIAL L-ARGININE/NO SIGNALLING PATHWAY REQUIRES A(2B) ADENOSINE RECEPTORS ACTIVATION IN HUMAN UMBILICAL VEIN ENDOTHELIUM FROM LATE-ONSET PREECLAMPSIA
MATERNAL OBESITY IMPAIRS MIGRATION OF FETAL ENDOTHELIUM INVOLVING ENDOPLASMIC RETICULUM STRESS
MATERNAL SUPRAPHYSIOLOGICAL HYPERCOLESTEROLEMIA LEADS TO ENDOTHELIAL DYSFUNCTION OF THE HUMAN FETOPLACENTAL MACRO AND MICROVASCULATURE
OBESITY IN PREGNANCY ALTERS RECYCLING OF HUMAN EQUILIBRATIVE NUCLEOSIDE TRANSPORT 1 (HENT1) IN HUMAN UMBILICAL VEIN ENDOTHELIUM FROM GESTATIONAL DIABETES
Gestational-Age Variations in Placenta-Derived Exosome Bioactivity and Proteomic Profiling in Maternal Plasma during Normal Healthy Pregnancy
Insulin requires normal expression of insulin receptor A and A(1) adenosine receptors activation to reverse the gestational diabetes-increased L-arginine transport in human umbilical vein endothelial cells
MATERNAL SUPRAPHYSIOLOGICAL HYPERCHOLESTEROLEMIA LEADS TO REDUCED NITRIC OXIDE SYNTHASE ACTIVITY ASSOCIATED WITH REDUCED LEVELS OF TETRAHYDROBIOPTERIN IN HUVEC
Hypoxia Increases Exosome Releases from Placental Mesenchymal Stem Cell (pMSC) and Promotes the Migration and Angiogenesis in Human Placental Microvascular Endothelial Cell (hPMEC).
Hypoxia Induces Exosome Deportation from Trophoblast Cells during the First Trimester of Pregnancy and Promotes Placental Mesenchymal Stem Cell Migration (pMSC).
MATERNAL OBESITY AND NEONATAL INSULIN RESISTANCE IN THE ORIGIN OF METABOLIC SYNDROME IN CHILDHOOD
PLACENTAL CELL-DERIVED EXOSOMES INCREASE IN MATERNAL CIRCULATION WITH GESTATIONAL AGE
Reduced Insulin Response in Human Umbilical Vein Endothelial Cells from Pregnancies with Maternal Obesity Is Associated with Activation of PERK Branch of Endoplasmic Reticulum Stress Pathway
INVOLVEMENT OF A(2A) ADENOSINE RECEPTORS IN INSULIN-INCREASED L-ARGININE TRANSPORT IN HUMAN UMBILICAL VEIN ENDOTHELIUM
RhoA/ROCK Signaling Pathway Is Not Implicated in the Regulation of eNOS Activation and arginase-2 Expression in Human Umbilical Vein Endothelial Cells Exposed to Hypoxia.
SREBP-1C AND HCHOP-C/EBP alpha INVOLVEMENT IN INSULIN MODULATION OF HENT2 ACTIVITY IN HUMAN PLACENTA MICROVASCULAR ENDOTHELIUM FROM GESTATIONAL DIABETES
SYNCYTIAL FORMATION REDUCES EXOSOME DEPORTATION FROM TROPHOBLAST CELLS
The Hypoxic Phenotype of IUGR Placental Endothelial Cells Is Reverted by DNMT1 Silencing. Evidence for Altered Epigenetic Vascular Programming.
Abnormal Expression of L-Arginine/NO-Related Enzymes in HUVEC Is Associated with Altered Vascular Reactivity of Umbilical Vein from IUGR Placentae
Altered Expression of L-Arginine/NO-Related Enzymes in Cultured Endothelial Cells from IUGR Placenta Is Accompanied by Specific DNA Methylation Changes
INSULIN ACTIVATES EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 2 INVOLVING INSULIN RECEPTOR A IN HUMAN PLACENTA MICROVASCULAR ENDOTHELIAL CELLS FROM GESTATIONAL DIABETES
INSULIN RECEPTOR A IS INVOLVED IN GESTATIONAL DIABETES-REDUCED ADENOSINE TRANSPORT VIA HUMAN EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1 IN HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS
Insulin Reverses Gestational Diabetes-Increased L-Arginine Transport Via A(2A) Adenosine Receptors Activation in Human Umbilical Vein Endothelium
Maternal Supraphysiological Hypercholesterolemia Leads to Reduced Endothelium-Dependent Vasodilation of Umbilical Vein and Increased L-Arginine Transport in HUVEC
ACTIVITY AND EXPRESSION OF HUMAN EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1 IS REGULATED BY D-GLUCOSE UPTAKE AND METABOLISM IN UMBILICAL VEIN ENDOTHELIUM
ADENOSINE TRANSPORT IS MEDIATED BY DIFFERENT NUCLEOSIDE TRANSPORTERS IN NON-DIFFERENTIATED AND DIFFERENTIATED HUMAN ENDOTHELIAL PROGENITOR CELLS
Antagonic Role of Adenosine A(2A) and A(2B) Receptors on L-Arginine/Nitric Oxide Pathway in Human Placental Microvascular Endothelial Cells from Pre-Eclampsia
CHRONIC INCUBATION WITH HIGH EXTRACELLULAR D-GLUCOSE INCREASES THE CONTRACTILITY OF HUMAN UMBILICAL VEIN RINGS
DIFFERENTIAL MODULATION OF INSULIN RECEPTOR ISOFORMS EXPRESSION AND NOS ACTIVITY BY INSULIN IN HUMAN PLACENTA MICROVASCULAR ENDOTHELIAL CELLS FROM GESTATIONAL DIABETES
Expression and Activity of Human Equilibrative Nucleoside Transporter 1 Depends on D-Glucose Uptake in Umbilical Vein Endothelial Cells.
Functional evidences of fetal endothelial dysfunction as a programmed phenomenon in pregnancy diseases
HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS EXHIBIT GLUTS-LIKE TRANSPORT ACTIVITY MODULATED BY INSULIN
Hypoxia-Reduced eNOS Activity Could Be Explained by Higher Arginase II Activity and Cellular Redistribution in Human Umbilical Vein Endothelial Cells
PARTICIPATION OF ARGINASES IN THE VASCULAR TONE IN UMBILICAL VEIN FROM IUGR PLACENTAE: ROLE OF THE ENDOTHELIUM AND HYPOXIA
RHOA/ROCK SIGNALLING PATHWAY IS NOT IMPLICATED IN ENOS INACTIVATION BY HYPOXIA IN HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS
Role of Arginase II in the Vascular Function of Umbilical Arteries and Veins: Effect of Hypoxia
THE REDUCED NOS-DEPENDENT VASODILATION IN IUGR CHORIONIC ARTERIES IS IMPROVED BY ARGINASE INHIBITION
VASOCONSTRICTION INDUCED BY SEROTONIN IS REDUCED BY ADENOSINE IN HUMAN UMBILICAL VEINS FROM GESTATIONAL DIABETES
Adenosine A(2B) Receptors Are Involved in the Regulation of Nitric Oxide Synthesis in Placental Microvascular Endothelial Cells from Preeclamptic Pregnancies
Upregulation of Arginase II in Hypoxia Counteracts Nitric Oxide Synthesis in Human Umbilical Vein Endothelial Cells
Adenosine, L-Arginine and Nitric Oxide Pathway in Human Placental Microvascular Endothelial Cells Derived from Preeclampsia.
Brain natriuretic peptide (BNP) decreases expression and activity of eNOS and iNOS in primary human myometrial cell cultures
Characterization of adenosine, L-arginine, and nitric oxide pathway in human placental microvascular endothelial cells derived from preeclampsia
D-Glucose increases the expression and activity of hCAT-1 and Spl binding to SLC7A1 promoter in human umbilical vein endothelium
Docosahexaenoic Acid (DHA) Supplementation Benefits Pregnancy Complicated with Gestational Diabetes Mellitus (GDM)
Gestational diabetes mellitus is associated with NO and PKC-dependent repressor effect of hCHOP-C/EBPalpha on equilibrative nucleoside transporter 1 expression human umbilical vein endothelium
Hypoxia upregulates the expression of arginase II in human umbilical vein endothelial cells. Regulating the nitric oxide synthase activity
Reduced tyrosine phosphorylation of inducible nitric oxide synthase in placentae from severe preeclamptic pregnancy
TGF-beta 1 inhibits adenosine transport in human fetal endothelium
The transcriptional repression of equilibrative nucleoside transporter 1 by D-glucose rfsponses to transcription factor Sp1 and ZBP-89 in human foetal endothelium
Transforming growth factor beta 1 is involved in the inhibitory effect of high D-glucose on human equilibrative nucleosidie transporter 1 in human fetal endothelium
ALANO pathway in the feto-placental endothelium from gestational diabetes
Expression and activty of HENT1 and HENT2 are regulated by adenosine receptors in placenta microvascular endothelium from preeclampsia
Insulin increases adenosine transport via equilibrative nucleoside transporter 2 in human umbilical vein endothelium under normoxia or hypoxia.
Lower activity of L-arginine-nitric oxide pathway is related to PKCA activation in human umbilical vein endothelium from intruterine growth restriction.
Preeclampsia is associated with increased adenosine transport via the human equilibrative nucleoside transporter 2 in placental microvascular endothelial cells.
Supplementation with docosahexaenoic acid (DHA) in women with gestational diabetes mellitus (GDM) in chile: Benefit to glucose tolerance and plasma lipids
Transcriptional repression of equilibrative nucleoside transporter 1 by D-glucose involves nitric oxide and Sp1 in human foetal endothelium
Transforming growth factor beta 1 reduces expression and activity of equilibrative nucleoside transporter 1 in human fetal endothelium
Adenosine receptor A2A stimulation decreases nitric oxide synthesis in placental microvascular endothelial cells from women with preeclampsia and intrauterine growth restriction
Adenosine transport via Equilibrative Nucleoside Transporters 1 and 2 are not modulated by insulin in human umbilical vein endothelium under hypoxia
Alano pathway in human umbilical vein endothelium
D-GLUCOSE stimulates nitric oxide synthase via a mechanism that involves TGF-beta 1 in human foetal endothelium
Differential regulation of adenosine transport by activation of A(2a) and A(1) purinoceptors in human umbilical vein endothelium
Effect of insulin on L-arginine transport through system y(+)L in human umbilical vein endothelium
Effects of insulin on the expression and activity of system y(+)L-mediated L-arginine transport in human umbilical vein endothelium
High D-glucose reduces promoter activity of human equilibrative nucleoside transporter 1 in human umbilical vein endothelium
Hypoxia increases equilibrative nucleoside transporter 2 activity by a transcriptional independent mechanism in human umbilical vein endothelium
Hypoxia represses carbon monoxide/heme oxygenase (Co/Ho) system and downregulates L-arginine/nitric oxide (No) pathway in human umbilical vein endothelial cells (Huvec).
Hypoxia-induced heme oxygenase-1 regulates the L-arginine/nitric oxide pathway in human umbilical vein endothelium
Inhibition of L-arginine transport and nitric oxide activity in human umbilical vein endothelium of newborn with intrauterine growth restriction: role of hypoxia and PKC
Insulin inhibits the stimulatory effect of D-glucose on L-arginine transport in human umbilical vein endothelium
Insulin restores D-glucose reduced adenosine transport in human umbilical vein endothelium
Isolation of microvascular endothelium from human placenta
Modulation of adenosine transport by insulin in human foetal endothelium
oxLDL effects in L-arginine/nitric oxide pathway in T-lymphocyte and human umbilical vein endothelial cells
Post-translational modulation of equilibrative nucleoside transporter 1 by D-glucose in human umbilical vein endothelium
Short-, but not long-term stimulation of L-arginine transport by D-glucose involves TGF-beta 1 in human foetal endothelium
Transcriptional repression of the equilibrative nucleoside transporter I in human umbilical vein endothelium from gestational diabetes
Effect of transforming growth factor beta 1 on L-arginine/nitric oxide pathway in human umbilical vein endothelium exposed to high D-glucose
Equilibrative nucleoside transporter 1 is downregulated by activation of A(2a) adenosine receptors in human umbilical vein endothelium.
Gestational diabetes increases L-arginine transport via a P13-K-independent mechanism in human foetal endothelium
Heme oxygenase 1 regulates the L-arginine/nitric oxide pathway in hypoxia in human umbilical vein endothelium
Insulin restores the elevated adenosine transport in human umbilical vein endothelial cells from intrauterine growth restriction pregnancies
Expression of equilibrative nucleoside transporters 1 is modulated by hypoxia in human umbilical vein endothelial cells
Transforming growth factor beta 1 increases L-arginine transport and expression of the human cationic amino acid transporter 1 mRNA in human umbilical vein endothelial cells
Gestational diabetes-induced increase in L-arginine transport and NO synthesis involves activation of protein kinases and increased eNOS and hCAT-1 mRNA in human fetal endothelium
Diabetes and hyperglicemia induced L-arginine/nitric oxide (NO) pathway in human fetal endothelium
Effect of hyperglycaemia on cellular localization of human equilibrative nucleoside transporters (hENT) in umbilical vein endothelial cells
Elevated D-glucose induces expression of the cationic amino acid transport system y(+)/CAT-2B and endothelial nitric oxide synthase in human fetal endothelial cells
Inhibition of L-arginine/nitric oxide pathway by oxidized low-density lipoprotein is associated with a reduction of hCAT-1 and hCAT-2B mRNA in human fetal endothelium
Intra-uterine growth retardation is associated with reduced activity and expression of cationic amino acid transporters (system y(+)/CAT) and nitric oxide synthase in human umbilical vein endothelial cells
Non-genomic and genomic effects of insulin as modulator of L-arginine/nitric oxide signalling pathway in human umbilical vein endothelial cells
Acute effect of D-glucose on L-arginine transport and nitric oxide synthesis in human fetal endothelium
Diabetes- and insulin-increased adenosine transport is associated with a higher number of nucleoside transporters in human umbilical artery smooth muscle cells
Diabetes-induced L-arginine transport is mediated by mitogen-activated protein kinases and nitric oxide in human fetal endothelial cells
Differential role of protein kinase C in D-glucose-induced inhibition of L-leucine and thymidine incorporation into macromolecules in human fetal endothelium
Gestational diabetes-induced nitrobenzylthioinosine-sensitive adenosine transport in human umbilical artery smooth muscle cells
How is nitric oxide involved in vascular relaxation during diabetes?
Inhibition of adenosine transport involves nitric oxide and mitogen-activated protein kinase in human fetal endothelium from diabetic pregnancy
Regulation of adenosine transport by insulin in human umbilical artery smooth muscle cells from diabetic pregnancies

BookReview (5)

Diseases of pregnancy and fetal programming: cell and molecular approaches.
Nitric Oxide function and dysfunction
Fetus and Placenta – A perfect harmony.
6th World Congress on Developmental Origins of Health and Disease
Transportalopathies

BookSection (29)

Maternal and fetal metabolic dysfunction in pregnancy diseases associated with vascular oxidative and nitrative stress.
Maternal hypercholesterolemia in gestational diabetes and the association with placental endothelial.
The adenosine-insulin signalling axis in the fetoplacental endothelial dysfunction in gestational diabetes.
The role of placenta in the fetal programming associated to gestational diabetes.
Oxidative stress in pregnancies complicated by diabetes
Oxidative stress in pregnancies complicated by diabetes.
The Role of Placental Exosomes in Gestational Diabetes Mellitus
The role of placental exosomes in gestational diabetes mellitus.
Transplacental transport of calcium in health and disease
Transplacental transport of calcium in health and disease.
Maternal Hypercholesterolemia in Gestational Diabetes and the Association with Placental Endothelial Dysfunction
The Adenosine–Insulin Signaling Axis in the Fetoplacental Endothelial Dysfunction in Gestational Diabetes
Fetoplacental vascular pathophysiology in preeclampsia.
Fetoplacental vascular pathophysiology in preeclampsia
Adenosine receptors: A novel therapeutic alternative for diabetic nephropathy
Placenta function.
Adenosine receptors: a novel therapeutic alternative for diabetic nephropathy.
Early origin of obesity and chronic diseases.
Membrane receptors involved in pregnancy myometrial quiescence.
Multidrug Resistance Proteins
Placenta programming in pregnancy diseases.
Role of equilibrative nucleoside transporters in fetal endothelial dysfunction in gestational diabetes
Role of equilibrative nucleoside transporters in fetal endothelial dysfunction in gestational diabetes.
Transportome and anti-cancer drugs effectiveness
Understanding high adenosine extracellular levels in feto-placental circulation during preeclamptic pregnancies
Characterization of transport systems for solutes at the blood side of endothelial and parenchymal cells by single circulation paired-tracer dilution. A review of recent studies.
Mecanismos moleculares asociados a la regulación del transporte y metabolismo de adenosina y L-arginina por hipoxia en endotelio fetal humano
Mecanismos moleculares asociados a la regulación del transporte y metabolismo de adenosina y L-arginina por hipoxia en endotelio fetal humano.
Solanum crispum R. et P.. I-Effects on some biological parameters.

BookWhole (2)

Gestational Diabetes - Causes, Diagnosis and Treatment.
Membrane Transporters and Receptors in Disease.

ConferencePaper (2)

STUDY OF THE COMBINED EFFECT OF ISOPROTERENOL AND MECHANICAL OSCILLATION ON THE CONTRACTILE RESPONSE OF MICE AIRWAYS FROM HEALTHY AND ASTHMATIC SUBJECTS (IN VIVO)
Combined effect of isoproterenol and mechanical oscillation on the contractile response of mice airway smooth muscle

Editorial (4)

Membrane transporters and receptors in pregnancy metabolic complications
Insulin Therapy, Insulin Resistance and Vascular Dysfunction
Molecular aspects of signalling in diabesity
Control of the Vasculature: Pharmacological Targets in Vascular Disease

EditorialMaterial (5)

Placental metabolism and disease
Nitric Oxide: A Regulator of Cellular Function in Health and Disease
Diseases of Pregnancy and Fetal Programming: Cell and Molecular Mechanisms
FETUS AND PLACENTA: A PERFECT HARMONY Preface
IFPA Meeting 2009 Workshops Report

Errata (1)

Synchronization in the Heart Rate and the Vasomotion in Rat Aorta: Effect of Arsenic Trioxide (vol 16, pg 79, 2016)

Letter (1)

Adenosine plasma levels in the fetoplacental circulation in preeclampsia

Patent (1)

Adenosine as modulator of insulin action in gestational diabetes

Proyecto (69)

Comparação da qualidade sexual de gestantes e da incontinência urinária específica da gestação entre mulheres brasileiras e chilenas
Comparação da qualidade sexual de gestantes e da incontinência urinária específica da gestação entre mulheres brasileiras e chilenas
Exosomes role in gestational diabetes-associated dysfunction of the fetoplacental vascular endothelium
hENT expression is modulated by epigenetics in fetoplacental endothelium from gestational diabetes mellitus
European Union (Erasmus+) International Master in Innovative Medicine (IMIM) (w/U Groningen (The Netherlands), U Heidelberg (Germany), Uppsala Universitet (Sweden), U Nacional de Méjico (UNAM), U Antioquia (Colombia), U Sao Paulo (Brazil)).
Excessive maternal gestational weight gain reduces the vascular endothelium-smooth muscle functional interaction involving endothelin-1 and nitric oxide in the human placenta
Involvement of PCSK9 in human maternal supraphysiological hypercholesterolemia. Effects on placental cholesterol traffic and function of neonatal lipoproteins.
INVOLVEMENT OF PCSK9 IN HUMAN MATERNAL SUPRAPHYSIOLOGICAL HYPERCHOLESTEROLEMIA. EFFECTS ON PLACENTAL CHOLESTEROL TRAFFIC AND FUNCTIONALITY OF NEONATAL LIPOPOROTEINS
ROLE OF INSULIN RECEPTORS AND ADENOSINE RECEPTORS IN PREVENTION OF FETOPLACENTAL ENDOTHELIAL DYSFUNCTION BY INSULIN IN WOMEN WITH GESTATIONAL DIABETES MELLITUS
Role of insulin receptors and adenosine receptors in prevention of fetoplacental endothelial dysfunction by insulin in women with gestational diabetes mellitus.
Role of RECK in the development of human preeclampsia as regulator of cytotrophoblast invasiveness and endovascular differentiation
Role of the axis Mg2+/exosomes/adenosine in reversing the human fetoplacental microvascular endothelial dysfunction in early-onset preeclampsia
IBTech AUT PhDFOR 2014 Institute of Biomedical Technology, Auckland University of Technology (PI Chile).
Regulacion por MAPK y PKC del efecto de insulina sobre el transporte de L-arginina via y+L en celulas endoteliales de vena umbilical humana
International network for the study of feto-placental vascular dysfunction in diseases of pregnancy
ROLE OF NA+/H+ EXCHANGER ISOFORM 1 (NHE1) AND HYPOXIA-INDUCIBLE TRANSCRIPTION FACTOR 2 ALPHA (HIF2A) AS A MEDIATORS OF OVARY CANCER CELL PROLIFERATION
UMCG RUG INT/2013 U Groningen, University Medical Center Groningen (PI in Chile).
UQCCR POSTD2013 U Queensland Center for Clinical Research (PI in Chile)
GESTATIONAL DIABETES AND OBESITY ALTER HUMAN EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1 RECYCLING IN HUMAN UMBILICAL VEIN ENDOTHELIUM
INTRAUTERINE PROGRAMMING OF HIPOXIA- AND OXIDATIVE STRESS-INDUCED VASCULAR RESPONSES IN PLACENTAL ENDOTHELIUM FROM IUGR AND MACROSOMIC FETUSES=> EARLY EVIDENCE FOR EPIGENETIC-DRIVEN VASCULAR DYSFUNCTION.
L-Carnitine and hypertension
MATERNAL OBESITY PRODUCES INSULIN RESISTANCE IN FETAL TISSUES INVOLVING ENDOPLASMIC RETICULUM STRESS
Modulation of expression and activity of hENT2 by insulin in placental microvascular endothelial cells (hPMEC) from gestational diabetes. (PI, Tutor)
Regulation of adenosine transport by insulin in astrocytes of mouse fetuses with gestational diabetes. (PI, Tutor)
Role of adenosine in insulin response of macro and microvascular human placental endothelium from gestational diabetes mellitus via insulin receptor subtypes A and B
ROLE OF ADENOSINE IN INSULIN RESPONSE OF MACRO AND MICROVASCULAR HUMAN PLACENTAL ENDOTHELIUM FROM GESTATIONAL DIABETES MELLITUS VIA INSULIN RECEPTOR SUBTYPES A AND B.
Characterization of the pathophysiological mechanisms, and detection of common therapeutic targets in placental dysfunction in pathologies of the human pregnancy
Science Club at preschool.
Reactividad vascular en diabetes gestacional en respuesta a insulina
ROL PARACRINO DEL PEPTIDO NATRIURETICO CEREBRAL (BNP) EN LA MANTENCION DE LA QUIESCENCIA MIOMETRIAL DEL EMBARAZO. ESTUDIO DE SUS VIAS DE SEQALIZACION CELULAR EN EL MIOMETRIO HUMANO
Nucleosides and gynaecologic cancer.
PAPEL DE ARGINASAS I Y II EN LA DISFUNCION ENDOTELIAL DE LA UNIDAD FETO-PLACENTARIA EN EMBARAZOS CON RESTRICCION DEL CRECIMIENTO INTRAUTERINO Y EN HIPOXIA
Post-translational modifications of hENTs in microvascular endothelium
REGULACION DE LA EXPRESION Y ACTIVIDAD DE LOS TRANSPORTADORES EQUILIBRADOS DE NUCLEOSIDOS TIPO 1 (HENT1) Y 2 (HENT2) POR INSULINA EN EL ENDOTELIO MICRO Y MACROVASCULAR FETAL HUMANO EN DIABETES MELLITUS GESTACIONAL.
Fetal vasculature alterations in gestational diabetes and hyperglycemia.
Insulin modulation of L-arginine transport in response to elevated D-glucose in human umbilical vein endothelial cells
Pathophysiology of purines on endothelial lacenta disfucion human intrauterine growth restriction and hypoxia=> cellular and molecular basis.
Post-translational modifications of plasma membrane proteins in pre-eclampsia
REGULACION DE LA EXPRESION Y ACTIVIDAD DE LOS TRANSPORTADORES EQUILIBRADOS DE NUCLEOSIDOS TIPO 1 (HENT1) Y 2 (HENT2) POR INSULINA EN EL ENDOTELIO MICRO Y MACROVASCULAR FETAL HUMANO EN DIABETES MELLITUS GESTACIONAL.
REGULACION DE LA EXPRESION Y ACTIVIDAD DE LOS TRANSPORTADORES EQUILIBRADOS DE NUCLEOSIDOS TIPO 1 (HENT1) Y 2 (HENT2) POR INSULINA EN EL ENDOTELIO MICRO Y MACROVASCULAR FETAL HUMANO EN DIABETES MELLITUS GESTACIONAL.
Caracterizacion del efecto de la activacion de en celulas endoteliales de vena umbilical humana
Endothelial dysfunction and TGF-b1 involvement.
Programa de intercambio académico
Transcriptional regulation of CNT and ENT transporters. Pathophysiological implications.
Efecto de insulina sobre la ruta L-arginina/oxido nitrico a traves del transportador y+L en endotelio de vena umbilical humana
Estabilidad del mRNA de hENT1 y hENT2 en endotelio fetal humano de diabetes gestacional
Papel de MAP kinasas en la regulacion del transporte de L-arginina via sistema y+L por insulina en HUVEC
Efecto de hipoxia experimental en la expresion de los transportadores hENT1 y hENT2 para nucleosidos en el endotelio fetal humano
Suplementacion con ocido docosahexenoico (DHA) en mujeres embarazadas con diabetes mellitus gestacional
REGULACION DE LA RUTA DE SENALIZACION L-ARGININA/OXIDO NITRICO EN ENDOTELIO DE VENA UMBILICAL DE FETOS CON RESTRICCION DEL CRECIMIENTO INTRAUTERINO (RCIU)
REGULACION TRANSCRIPCIONAL DEL TRANSPORTADOR EQUILIBRATIVO DE NUCLEOSIDOS ENT1 POR D-GLUCOSA EN ENDOTELIO HUMANO.
REGULACION TRANSCRIPCIONAL DEL TRANSPORTADOR EQUILIBRATIVO DE NUCLEOSIDOS ENT1 POR D-GLUCOSA EN ENDOTELIO HUMANO.
Relacion entre la localizacion y distribucion celular y estado de activacion de moleculas de señalizacion en la produccion de oxido nitrico en celulas endoteliales
VITAMINA C Y ESTRES OXIDATIVO=> MECANISMO Y FACTORES MODULADORES
Efecto del retardo del crecimiento intrauterino (RCIU) e hipoxia en la regulacion de la ruta de señalizacion L-arginina/oxido nitrico en endotelio fetal humano
Expresion de Lax-1 en el desarrollo embrionario en diabetes
Fisiologia celular y molecular de transportadores y receptores en desarrollo, diferenciacion, neoplasia y muerte celular
CARACTERIZACION DEL EFECTO INHIBITORIO DE GLUCOSA SOBRE EL TRANSPORTE DE ADENOSINA EN ENDOTELIO HUMANO=> IMPORTANCIA DEL OXIDO NITRICO, PROTEINA KINASA C Y MAP KINASAS.
El consumo habitual de cocaina puede alterar el transporte de aminoacidos en globulos rojos humanos. Singularidades en el transporte de L-arginina
Modulacion del transporte de adenosina por cGMP y cAMP en endotelio fetal humano
A molecular-genetic approach to the analysis of the role of nitric oxide and arginine transport in breast tumor metastasis
Efectos del consumo de cocaina sobre la ruta L-arginina/oxido nitrico en celulas vasculares humanas
EFECTO DE DIABETES MELLITUS SOBRE LA REGULACION DEL TRANSPORTE Y METABOLISMO DE ADENOSINA Y L-ARGININA EN CULTIVOS DE ENDOTELIO DE VENA UMBILICAL HUMANA
Open Lab Day
TRANSPORTE DE AMINOACIDOS EN GLANDULAS GASTRICAS DE MAMIFERO
Role of the placental transport of metabolites in the diabetic embryopathy
ESTUDIO DEL TRANSPORTE DE SUBSTRATOS METABOLICOS EN LA PLACENTA HUMANA Y ANIMAL
Nucleoside transport and metabolism in placental and fetal nutrition
Science Club at preschool

Review (29)

Altered maternal metabolism during mild gestational hyperglycemia as a predictor of adverse perinatal outcomes: A comprehensive analysis
DNA methylation changes in genes coding for leptin and insulin receptors during metabolic-altered pregnancies
Placental structure in gestational diabetes mellitus
Role of heme oxygenase 1 and human chorionic gonadotropin in pregnancy associated diseases
Role of insulin, adenosine, and adipokine receptors in the foetoplacental vascular dysfunction in gestational diabetes mellitus
Altered foetoplacental vascular endothelial signalling to insulin in diabesity
Extracellular Vesicles and Insulin Resistance: A Potential Interaction in Vascular Dysfunction
Glioma progression in diabesity
Insulin Therapy in Pregnancy Hypertensive Diseases and its Effect on the Offspring and Mother Later in Life
Maternal Dyslipidaemia in Pregnancy with Gestational Diabetes Mellitus: Possible Impact on Foetoplacental Vascular Function and Lipoproteins in the Neonatal Circulation
Extracellular vesicles in obesity and diabetes mellitus
Foetoplacental communication via extracellular vesicles in normal pregnancy and preeclampsia
Insulin therapy and its consequences for the mother, foetus, and newborn in gestational diabetes mellitus
Is there a role for exosomes in foetoplacental endothelial dysfunction in gestational diabetes mellitus?
Role of extracellular vesicles in glioma progression
Cardiovascular Action of Insulin in Health and Disease: Endothelial L-Arginine Transport and Cardiac Voltage-Dependent Potassium Channels
Insulin therapy and fetoplacental vascular function in gestational diabetes mellitus
Programming of Fetal Insulin Resistance in Pregnancies with Maternal Obesity by ER Stress and Inflammation
Role of Insulin and Adenosine in the Human Placenta Microvascular and Macrovascular Endothelial Cell Dysfunction in Gestational Diabetes Mellitus
New therapeutic approaches to treating hypertension in pregnancy
Fetoplacental Vascular Endothelial Dysfunction as an Early Phenomenon in the Programming of Human Adult Diseases in Subjects Born from Gestational Diabetes Mellitus or Obesity in Pregnancy
Do Adenosine Receptors Offer New Therapeutic Options for Diabetic Nephropathy?
Equilibrative Nucleoside Transporters in Fetal Endothelial Dysfunction in Diabetes Mellitus and Hyperglycaemia
Potential Cell Signalling Mechanisms Involved in Differential Placental Angiogenesis in Mild and Severe Pre-Eclampsia
A hypothesis for preeclampsia: Adenosine and inducible nitric oxide synthase in human placental microvascular endothelium
Equilibrative nucleoside (ENTs) and cationic amino acid (CATs) transporters: Implications in foetal endothelial dysfunction in human pregnancy diseases
Gestational diabetes and the adenosine/L-arginine/nitric oxide (ALANO) pathway in human umbilical vein endotheliurn
Regulation of amino acid and glucose transporters in endothelial and smooth muscle cells
Tumorogenesis and mdm2 protein
345
LUIS SOBREVIA

Professor

Division of Obstetrics and Gynaecology

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

97
Paola Casanello

Profesor Asociado

División de Obstetricia y Ginecología

Pontificia Universidad Católica de Chile

Santiago, Chile

83
Andrea Leiva

Profesor Asociado

Facultad de Ciencias de la Salud

Universidad San Sebastián

Santiago, Chile

46
Marcelo Farias

Assistant Professor

Division of Obstetrics and Gynecology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, DEPARTAMENTO DE OBSTETRICIA

Santiago, Chile

43
Fabian Pardo

Profesor titular

Escuela de Medicina

Universidad de Valparaiso

San Felipe, Chile

28
Carlos Escudero

Full Professor

Basic Sciences Department

Universidad del Bio Bio

Chillan, Chile

27
Rody San Martín

Professor

Sciences Faculty

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

26
Carlos Salomón

Academic

University of Concepcion

Concepcion, Chile

25
Enrique Guzman

Profesor Asistente

Bioquímica Clínica e Inmunología

Universidad de Concepción

Concepción, Chile

25
Bernardo Krause

Associate Professor

Insituto de Ciencias de la Salud

Universidad de O'Higgins

Rancagua, Chile

21
Carlos Puebla

Profesor Asistente

Universidad de O'Higgins

Rancagua, Chile

20
Jaime Gutierrez

Associate Professor and Researcher

Tecnología Médica

Universidad San Sebastián

Santiago, Chile

20
Claudio Aguayo

Profesor Asociado

Bioquimica Clinica e Inmunologia

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

20
Carlos Puebla

Assistant Professor

Universidad de O'Higgins

Santiago, Chile

14
Tamara Sáez

Postdoctoral fellow

Obstetrics and Gynecology

University of Alberta

Edmonton, Canada

13
Alejandro Yanez

Full professor

Faculty of Science

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

13
Roberto Villalobos

Académico

Facultad de Medicina

Universidad de Valparaíso

San Felipe, Chile

13
CATALINA PRIETO

Investigadora senior

Biología

Universidad de Chile

Santiago, Chile

12
Carlos Flores

Researcher

Biology Lab

CENTRO DE ESTUDIOS CIENTÍFICOS (CECS)

Valdivia, Chile

11
Francisco Westermeier

Universidad de Chile

Santiago, Chile

10
MARCO RAMIREZ

Associate Professor

Universidad de Antofagasta

Antofagasta, Chile

7
Claudia Quezada

Full Professor

Institute of Biochemistry and Microbiology

Universidad Austral de Chile

Valdivia, Chile

6
Delia Chiarello

Investigador

Facultad de Ciencias de la Salud

Universidad San Sebastián

Santiago, Chile

5
Liliana Lamperti

Vicedecana

UNIVERSIDAD DE CONCEPCIÓN, FACULTAD DE FARMACIA

Concepción, Chile

5
Ana Beltrán

Profesor asociado

Educación

Universidad de Antofagasta

Antofagasta, Chile

4
Sebastián Illanes

professor, Director of Reproductive Biology Laboratory

Medicine

UNIVERSIDAD DE LOS ANDES

Santiago, Chile

4
Luis Cea

Profesor programa teaching

Instituto de Ciencias Biomédicas

Universidad Autónoma de Chile

Santiago, Chile

4
Sebastian San Martin

Profesor Titular

Anatomía

UNIVERSIDAD DE VALPARAISO

Valparaiso, Chile

4
Fernando Abarzua

Assitant researcher

Universidad de La Frontera

Temuco, Chile

4
MARCELO CORNEJO

Académico

Biomédico

Universidad de Antofagasta

Antofagasta, Chile

4
Andrea Vecchiola

Profesor Asistente

Endocrinologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

3
Sebastián Alarcón

Profesor Asistente

Medicina y Ciencia

Universidad San Sebastián

Concepcion, Chile

3
Claudette Cantin

Profesor Asistente

Universidad San Sebastián

Puerto Montt, Chile

3
Juan Kusanovic

Jefe CIMAF

Obstetricia y Ginecología

SERV. DE SALUD METROPOLITANA SUR ORIENTE, HOSPITAL SOTERO DEL RIO

Santiago, Chile

2
CORALIA RIVAS

Associated Professor

Pathophysiology

UNIVERSIDAD DE CONCEPCION

CONCEPCION, Chile

2
Astrid Haensgen

Investigadora

Universidad San Sebastián

Concepción, Chile

2
Susana Contreras

Assistant Professor

Nutrition and Dietetics

Universidad San Sebastián

Santiago, Chile

2
Ángelo Torres

Postdoctorado/Profesor Adjunto

Microbiología y Bioquímica

Universidad Austral de Chile

Valdivia, Chile

2
Juan Vera

Full professor

Pathophysiology

University of Concepcion

Concepción, Chile

2
Viviana Montecinos

Assistant Professor

Hematology Oncology

Pontificia Universidad Catolica de Chile

Santiago, Chile

2
Bastian Sobrevia

Médico en etapa de Destinación y Formación

Servicio de Salud del Reloncaví

Puerto Montt, Chile

2
Julián Varas

Coordinador Médico Centro de Simulación, miembro directorio Simulación UC

Departamento de Cirugía Digestiva

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

2
Juan Carcamo

Profesor Titular

Instituto de Bioquímica y Microbiología

Universidad Austral de Chile

Valdivia, Chile

2
Gareth Owen

Profesor Titular

Fisiologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

2
Jose Luis Vega

Profesor Asociado

Biomedico

Universidad de Antofagasta

Antofagasta, Chile

2
Bredford Kerr

Profesor Asociado

CEBICEM

Universidad San Sebastián

Santiago, Chile

2
Carlos Veas

BIOQIUMICO

MEDICINA

HOSPITAL REGIONAL GUILLERMO GRANT BENAVENTE

CONCEPCION, Chile

2
Daniel Uribe

Profesor Adhonorem

Institute of Biochemistry and Microbiology

Universidad Austral de Chile

Valdivia, Chile

2
Leandro Zuñiga

Profesor Asociado

Medicine

Universidad de Talca

Talca, Chile

1
Jaime Riquelme

Assistant Professor

Química Farmacológica y Toxicológica

Universidad de Chile

Santiago, Chile

1
Fernando Ezquer

Full Professor

Center for Regenerative Medicine

Universidad del Desarrollo

Santiago, Chile

1
SERGIO LAVANDERO

Director

Advanced Center for Chronic Diseases (ACCDiS)

UNIVERSIDAD DE CHILE, FAC CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

1
Floria Pancetti

Director de Departamento

Ciencias Biomédicas

UNIVERSIDAD CATOLICA DEL NORTE

Coquimbo, Chile

1
Fernando Moraga

Profesor Asociado

Ciencias Biomédicas

UNIVERSIDAD CATÓLICA DEL NORTE

Coquimbo, Chile

1
David Contador

Professor Instructor

School of Medicine

Universidad del Desarrollo

Santiago, Chile

1
David Contador

Universidad del Desarrollo

Santiago, Chile

1
Patricio Bertoglia

Profesor asistente

Ciencias Basicas y Clinicas

Universidad Católica de la Santisima Concepción

Chillan, Chile

1
José Poblete

Jefe de Deparatmento

Departamento Obstetricia y Ginecologia

HOSPITAL CLÍNICO UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Mauricio Ibacache

Profesor Asociado

Pontificia Universidad Católica de Chile

santiago centro, Chile

1
Clemente Palacios

Académico

Química y Farmacia

Universidad Arturo Prat

Iquique, Chile

1
Sebastián Calligaris

Cordinador de Estudios Clínicos

Clínica Alemana

Santiago, Chile

1
Carlos Lafourcade

Profesor Asociado

UNIVERSIDAD DE LOS ANDES

Chile

1
ANDRES KLEIN

Assistant Professor/Director (Head) Center for Genetics and Genomics; Director, PhD Program in Sciences and Innovation in Medicine

Centro de Genética y Genómica

Universidad del Desarrollo-Clínica Alemana

SANTIAGO, Chile

1
Carmen Aravena

Acádemico

Universidad de Valparaíso

San Felipe, Chile

1
Felipe Zuñiga

Profesor Asistente

Bioquimica Clinica e Inmunologia

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

1
Marcelo González

Profesor Asistente

Obstetricia y Ginecología

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

1
Mario Chiong

Profesor

Departamento de Bioquímica y Biología Molecular

Universidad de Chile

Santiago, Chile

1
Romulo Melo

Neurosurgeon

Department of Neurosurgery

Instituto de Neurocirugía Dr. Asenjo

Santiago, Chile

1
Carlos Oyarzún

Profesor Adjunto Asociado

Ciencias

Universidad Austral de Chile

Valdivia, Chile

1
Enrique Brandan

Profesor Titular

Biología Celular y Molecular

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

1
Pedro Buc

Profesor titular

Quimica y Farmacia

Universidad Arturo Prat

Iquique, Chile

1
Denisse Valladares

Assistant Professor

Universidad de O'Higgins

Rancagua, Chile

1
Jorge Araya

Profesor Asociado

Departamento de Tecnología Médica

Universidad de Antofagasta

Antofagasta, Chile

1
Estefania Nova

Assistant Professor

Clinical Biochemistry & Immunology

University of Concepcion

Concepción , Chile

1
Katia Fernández

Académico - Profesor Asociado

Facultad de Salud y Odontología

Universidad Diego Portales

Santiago, Chile

1
Emilce Diaz

Profesor Asociado

Biomédico

UNIVERSIDAD DE ANTOFAGASTA

Antofagasta, Chile

1
FRANCISCO NUALART

Full Professor and Scientific Director

Cellular Biology and Center for Advanced Microscopy CMA BIO-BIO

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

1
Julio Alarcón

Docente

Ciencias Básicas

UNIVERSIDAD DEL BÍO-BÍO

Chillan, Chile

1
natalia rodriguez

Encargada de Programa de Prevencion y Control VIH/Sida e ITS, Servicio de Salud Ñuble

Direccion de Atención Primaria

Servicio de Salud Ñuble

Chillán, Chile

1
José Rocha

Postdoctoral Researcher

Facultad de Veterinaria

Universidad San Sebastián

Puerto Montt, Chile

1
Sharin Valdivia

Profesor Adjunto Adhonorem

Facultad de Ciencias

Universidad Austral de Chile

Valdivia, Chile

1
Patricia Ojeda

Research Assistant

Facultad de medicina

Universidad de Chile

Santiago, Chile

1
Carolina Cabalín

Investigadora

Pediatría

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Sebastián Gutiérrez

Asistente de Investigación

Bioquímica Clínica e Inmunología

Universidad de Concepción

Concepción, Chile

1
ivo carrasco

Investigador

Universidad San Sebastián

Santiago, Chile

1
Julio Benites

Profesor Titular

Química y Farmacia

Universidad Arturo Prat

Iquique, Chile

1
Sebastián Dubo

Profesor Asociado

Kinesiología

Universidad de Concepción

Concpeción, Chile