Man

Luis Andrés Cea Pisani

Profesor programa teaching

Universidad Autónoma de Chile

Santiago, Chile

Líneas de Investigación


músculo estriado; hemicanales formados por conexinas; miopatías; distrofias musculares

Educación

  •  Doctor en Ciencias Fisiológicas, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2012
  •  Magister en Ciencias Biológicas, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2008
  •  Bioquímico, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2007

Experiencia Académica

  •   Profesor Asistente Full Time

    UNIVERSIDAD DE CHILE

    Medicina

    Santiago, Chile

    2015 - A la fecha

  •   Docente Part Time

    UNIVERSIDAD AUTONOMA DE CHILE

    Ciencias de la Salud

    Chile

    2018 - A la fecha

Experiencia Profesional

  •   Docente Part Time

    Universidad Autónoma de Chile

    Santiago, Chile

    2018 - A la fecha

  •   Profesor Asistente Full Time

    Universidad de Chile

    Santiago, Chile

    2015 - A la fecha


 

Article (27)

Active acetylcholine receptors prevent the atrophy of skeletal muscles and favor reinnervation
Myofibers deficient in connexins 43 and 45 expression protect mice from skeletal muscle and systemic dysfunction promoted by a dysferlin mutation
Vitamin E Blocks Connexin Hemichannels and Prevents Deleterious Effects of Glucocorticoid Treatment on Skeletal Muscles
De novo expression of functional connexins 43 and 45 hemichannels increases sarcolemmal permeability of skeletal myofibers during endotoxemia
SEPSIS-INDUCED CHANNELOPATHY IN SKELETAL MUSCLES IS ASSOCIATED WITH EXPRESSION OF NON-SELECTIVE CHANNELS
Biophysical Properties of Connexin 39 Hemichannels Expressed in HeLa Cells
On Biophysical Properties and Sensitivity to Gap Junction Blockers of Connexin 39 Hemichannels Expressed in HeLa Cells
Sepsis-Induced Channelopathy in Skeletal Muscles is Associated with Expression of Non-Selective Channels
Dexamethasone-induced muscular atrophy is mediated by functional expression of connexin-based hemichannels
Fast skeletal myofibers of mdx mouse, model of Duchenne muscular dystrophy, express connexin hemichannels that lead to apoptosis
The absence of dysferlin induces the expression of functional connexin-based hemichannels in human myotubes
The absence of dysferlin induces theexpression of functional connexin-based hemichannels in human myotubes. BMC Cell Biology.
Pannexin channels mediate the acquisition of myogenic commitment in C2C12 reserve cells promoted by P2 receptor activation
Pannexin channels mediate the acquisition of myogenic commitment in C2C12 reserve cells promoted by P2 receptor activation.
Extracellular gentamicin reduces the activity of con nexin hemichannels and interferes with purinergic Ca2+ signaling in HeLa cells
Extracellular gentamicin reduces the activity of connexin hemichannels and interferes with purinergic Ca(2+) signaling in HeLa cells.
Pannexin 1 channels in skeletal muscles
Pannexin 1 channels in skeletal muscles.
De novo expression of connexin hemichannels in denervated fast skeletal muscles leads to atrophy
De novo expression of connexin hemichannels in denervated fast skeletal muscles leads to atrophy.
The ATP required for potentiation of skeletal muscle contraction is released via pannexin hemichannels
The ATP required for potentiation of skeletal muscle contraction is released via pannexin hemichannels.
Connexin- and pannexin-based channels in normal skeletal muscles and their possible role in muscle atrophy.
Denervation induces functional expression of connexin hemichannels followed by an inflammatory state in fast skeletal muscles.
Dexamethasone induces inflammation through expression of functional connexin hemichannels in skeletal muscle fibers.
Boldin reduces complications in diabetic rats
Insulin restores glucose inhibition of adenosine transport by increasing the expression and activity of the equilibrative nucleoside transporter 2 in human umbilical vein endothelium

Abstract (6)

Denervation induces functional expression of connexin hemichannels followed by an inflammatory state in fast skeletal muscles.
Dexamethasone induces inflammation through expression of functional connexin hemichannels in skeletal muscle fibers.
Boldin reduces complications in diabetic rats
Insulin increases adenosine transport via equilibrative nucleoside transporter 2 in human umbilical vein endothelium under normoxia or hypoxia.
Adenosine transport via Equilibrative Nucleoside Transporters 1 and 2 are not modulated by insulin in human umbilical vein endothelium under hypoxia
Modulation of adenosine transport by insulin in human foetal endothelium

Proyecto (5)

EXPRESSION OF FUNCTIONAL CONNEXIN-BASED HEMICHANNELS IN SKELETAL MUSCLES OF DYSFERLIN-DEFICIENT MICE, AN ANIMAL MODEL OF DYSFERLINOPATHY, FAVORS MUSCLE DAMAGE AND DYSFUNCTION
Mecanismos moleculares y celulares del daño muscular producido en disferlinopatías=> Rol de los hemicanales formados por conexinas
Mecanismos moleculares y celulares del daño muscular producido en disferlinopatías=> rol de los hemicanales formados por conexinas
CONNEXIN HEMICHANNELS AS MEDIATORS OF SARCOLEMMAL AND MITOCHONDRIAL DYSFUNCTION IN RESPIRATORY AND PERIPHERAL MUSCLE IN THE PATHOGENESIS OF SEPSIS ASSOCIATED-INTENSIVE CARE UNIT ACQUIRED WEAKNESS (ICUAW)
Molecular and cellular mechanisms of muscular dystrophy related to mutations of dysferlin

Review (2)

Dysferlin function in skeletal muscle: Possible pathological mechanisms and therapeutical targets in dysferlinopathies
Connexin- and Pannexin-Based Channels in Normal Skeletal Muscles and Their Possible Role in Muscle Atrophy
22
Luis Cea

Profesor programa teaching

Instituto de Ciencias Biomédicas

Universidad Autónoma de Chile

Santiago, Chile

11
Juan Saez

Professor

Instituto de Neurociencias

Universidad de Valparaiso

Valparaíso, Chile

7
Carlos Puebla

Profesor Asistente

Universidad de O'Higgins

Rancagua, Chile

6
Carlos Puebla

Assistant Professor

Universidad de O'Higgins

Santiago, Chile

4
LUIS SOBREVIA

Professor

Division of Obstetrics and Gynaecology

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

4
ROSALBA ESCAMILLA

Investigador asociado

Fisiología

Pontificia Universidad Católica de Chile

Santiago, Chile

4
Cristian Vilos

Profesor Jornada Completa

Medicina

Universidad de Talca

Talca, Chile

4
Juan Sáez

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

4
Paola Casanello

Profesor Asociado

División de Obstetricia y Ginecología

Pontificia Universidad Católica de Chile

Santiago, Chile

3
Aníbal Vargas

Investigador postdoctoral

Universidad de O'Higgins

Rancagua, Chile

2
Jorge Bevilacqua

Profesor Titular

Neurología y Neurocirugía

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA, ESCUELA DE MEDICINA

Santiago, Chile

2
Pablo Caviedes

Full professor

ICBM

PROGRAMA DE FARMACOLOGÍA MOLECULAR Y CLÍNICA, ICBM, FAC. DE MEDICINA, U. DE CHILE

Santiago, Chile

2
Marcelo Farias

Assistant Professor

Division of Obstetrics and Gynecology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, DEPARTAMENTO DE OBSTETRICIA

Santiago, Chile

2
ELISA BALBOA

Académico Investigador

Facultad de Medicina

Universidad Finis Terrae

SANTIAGO, Chile

1
Mauricio Retamal

Associate Professor

Centro de Fisiología Celular e Integrativa

Universidad del Desarrollo

Santiago, Chile

1
Jose Luis Vega

Profesor Asociado

Biomedico

Universidad de Antofagasta

Antofagasta, Chile

1
ramon latorre

Profesor

Instituto de Neurociencia

Universidad de Valparaíso

5, Chile

1
vania figueroa

Coordinadora de Vinculación de Investigación Aplicada

Centro de Comunicación de las Ciencias

Universidad Autónoma de Chile

Santiago, Chile

1
Xavier Figueroa

Associate Professor

Departamento de Fisiologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Agustin Martinez

Profesor Titular

Instituto de Neurociencia

UNIVERSIDAD DE VALPARAÍSO, CENTRO INTERDISCIPLINARIO DE NEUROCIENCIAS DE VALPARAÍSO

Valparaíso, Chile

1
Andrea Vecchiola

Profesor Asistente

Endocrinologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Carlos Lagos

Profesor Asociado

FACULTAD DE MEDICINA Y CIENCIA

UNIVERSIDAD SAN SEBASTIÁN

SANTIAGO, Chile

1
Daniel Escobar

PROFESIONAL

SALUD AMBIENTAL

INSTITUTO DE SALUD PÚBLICA DE CHILE

SANTIAGO, Chile

1
Rody San Martín

Professor

Sciences Faculty

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile