PDI - Resultado de Búsqueda

Juan Carlos Sáez Carreño

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

immunology; cell death; cellular biology; neurobiology; cellular communication


Angiotensin II-Induced Mesangial Cell Damage Is Preceded by Cell Membrane Permeabilization Due to Upregulation of Non-Selective Channels Gomez, Gonzalo, I; Fernandez, Paola; Velarde, Victoria; Saez, Juan C Article ISI SCOPUS INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Role of calcium permeable channels in dendritic cell migration Saez, Juan C; Vargas, Pablo Article ISI SCOPUS CURRENT OPINION IN IMMUNOLOGY (2018)
Trypanosoma cruzi Infection Induces Pannexin-1 Channel Opening in Cardiac Myocytes Cifuentes, Fredi; Zamorano, Pedro; Saez, Juan C Article ISI SCOPUS AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE (2018)
ATP promotes the fast migration of dendritic cells through the activity of pannexin 1 channels and P2X(7) receptors Article ISI SCOPUS Science Signaling (2017)
Connexins and pannexins in Alzheimer's disease Article SCOPUS Neuroscience Letters (2017)
Inhibition of glial hemichannels by boldine treatment reduces neuronal suffering in a murine model of Alzheimer's disease Yi C. Article ISI SCOPUS GLIA (2017)
Sepsis-Induced Channelopathy in Skeletal Muscles is Associated with Expression of Non-Selective Channels Article SCOPUS Shock (2017)
A Soluble Activin Receptor IIB Fails to Prevent Muscle Atrophy in a Mouse Model of Spinal Cord Injury Graham Z.A.; Collier, L; Peng, Y.; Sáez, J.C.; Bauman W.A.; Qin W. Article ISI SCOPUS JOURNAL OF NEUROTRAUMA (2016)
Fast skeletal myofibers of mdx mouse, model of Duchenne muscular dystrophy, express connexin hemichannels that lead to apoptosis Cea L.A.; Puebla, C; Escamilla, R; Frank M.; Martínez-Montero P.; Prior C.; Molano J.; Esteban-Rodríguez I.; Pascual, I.; Gallano, P; et al. Article ISI SCOPUS CELLULAR AND MOLECULAR LIFE SCIENCES (2016)
Linoleic acid permeabilizes gastric epithelial cells by increasing connexin 43 levels in the cell membrane via a GPR40-and Akt-dependent mechanism Puebla, C; Salas D.P.; Sáez, J.C. Article ISI SCOPUS BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2016)
Neural progenitor cells isolated from the subventricular zone present hemichannel activity and form functional gap junctions with glial cells Talaverón R.; Fernandez, P; Escamilla, R; Sáez, J.C. Article ISI SCOPUS Frontiers in Cellular Neuroscience (2015)
Extracellular gentamicin reduces the activity of con nexin hemichannels and interferes with purinergic Ca2+ signaling in HeLa cells Figueroa V.A.; Retamal, MA; Cea L.A.; Jara, O; Martinez A.D.; Sáez, J.C. Article ISI SCOPUS FRONTIERS IN CELLULAR NEUROSCIENCE (2014)
Gap Junction Intercellular Communication Mediated by Connexin43 in Astrocytes Is Essential for Their Resistance to Oxidative Stress Le H.T.; Sin W.C.; Lozinsky, S; Bechberger, J; Vega, J. L.; Sáez, J.C. Article ISI JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Connexin 36 is Expressed in Beta and Connexins 26 and 32 in Acinar Cells at the End of the Secondary Transition of Mouse Pancreatic Development and Increase During Fetal and Perinatal Life Cruz-Miguel L.; Coronel-Cruz C.; Esparza-Aguilar M.; Pinzon-Estrada E.; Rancano-Camacho E.; Zacarias-Climaco G.; Becker, I; Sáez, J.C.; Berumen J.; Perez-Palacios G. Article ISI SCOPUS Anatomical Record (2012)
Connexin-based channels in astrocytes: How to study their properties Giaume C.; Orellana J.A.; Abudara, V; Sáez, J.C. Article SCOPUS Methods in Molecular Biology (2012)
Critical role of the first transmembrane domain of Cx26 in regulating oligomerization and function Jara, O; Acuña R.; Maripillán J; Figueroa, V; Sáez, J.C.; Araya-Secchi R.; Lagos, C. F.; Perez-Acle, T; Martinez A.D. Article ISI SCOPUS MOLECULAR BIOLOGY OF THE CELL (2012)
Glucose increases intracellular free Ca2+ in tanycytes via ATP released through connexin 43 hemichannels Orellana J.A.; Cortes-Campos, C; Contreras-Duarte, S; Figueroa, V; Velarde, V; Nualart, F.; Sáez, J.C.; García, MA Article ISI SCOPUS GLIA (2012)
Permeation of Calcium through Purified Connexin 26 Hemichannels Fiori M.C.; Figueroa, V; Sáez, J.C.; Reuss L. Article ISI SCOPUS JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Regulation of Intercellular Calcium Signaling Through Calcium Interactions with Connexin-Based Channels Orellana J.A.; Schalper K.A.; Figueroa, V; SANCHEZ, H.A.; Sáez, J.C. Article ISI SCOPUS ARTERIAL CHEMORECEPTORS (2012)
Release of gliotransmitters through astroglial connexin 43 hemichannels is necessary for fear memory consolidation in the basolateral amygdala Stehberg, J; Moraga-Amaro, R.; Salazar, C; Becerra, A; Echeverría, C.; Orellana J.A.; Bultynck G.; Ponsaerts, R; Leybaert, L; Simon, F; et al. Article ISI SCOPUS FASEB Journal (2012)
Boldina disminuye la apoptosis miocárdica post isquemia reperfusión en la rata Lopez, Rene; Arismendi, Marlene; Sáez, Juan Carlos; Godoy, Ivan; Ocaranza, Maria Paz Article SCIELO REVISTA CHILENA DE CARDIOLOGIA (2011)
TNF-? plus IFN-? induce connexin43 expression and formation of gap junctions between human monocytes/macrophages that enhance physiological responses Sáez, J.C. Article SCOPUS JOURNAL OF IMMUNOLOGY (2003)
Activation of human polymorphonuclear cells induces formation of functional gap junctions and expression of connexins Sáez, J.C. Article SCOPUS Medical Science Monitor (2002)


HIV infection of astrocytes increases release of Dickkopf-1 protein by a gap junction and hemichannel dependent mechanism Orellana J.; Saez, J; Berman, J; Eugenin, E Abstract ISI JOURNAL OF NEUROVIROLOGY (2012)
Specific ablation of connexin 43 delays skeletal muscle regeneration in vivo Araya, R; Eckardt, D; Maxeiner, S; Kruger, O; Theis, M; Willecke K.; Saez, J Abstract ISI MOLECULAR BIOLOGY OF THE CELL (2002)


Connexin and Pannexin Based Channels in the Nervous System: Gap Junctions and More Sáez, J.C.; Nicholson, B BookWhole SCOPUS From Molecules to Networks: An Introduction to Cellular and Molecular Neuroscience: Third Edition (2014)


Uncovering the role of hemichannelsin glial and neuronal dysfunction induced by alpha-synnuclein Proyecto (2016)
Neuronal derived factor(s) and mechanism(s) that repress the expression of nonselective ion channels in normal adult skeletal muscles Puebla, Carlos Proyecto (2015)


Role of astrocyte connexin hemichannels in cortical spreading depression Review ISI BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2018)
Connexin-Dependent Neuroglial Networking as a New Therapeutic Target Charvériat M. Review ISI SCOPUS FRONTIERS IN CELLULAR NEUROSCIENCE (2017)
Connexins and Pannexins in Bone and Skeletal Muscle Plotkin L.I.; Davis H.M. Review ISI SCOPUS CURRENT OSTEOPOROSIS REPORTS (2017)
Biological mechanisms involved in the spread of traumatic brain damage Rovegno, M; Soto P.A.; Sáez, J.C.; von Bernhardi R. Review ISI SCOPUS Medicina Intensiva (2012)
Connexin and pannexin hemichannels in inflammatory responses of glia and neurons Bennett, M. V. L.; Orellana J.A.; Nedergaard M.; Sáez, J.C. Review ISI SCOPUS Brain Research (2012)
Connexin- and Pannexin-Based Channels in Normal Skeletal Muscles and Their Possible Role in Muscle Atrophy Cea L.A.; Riquelme, M. A.; Puebla, C; Vega, J. L.; Rovegno, M; Sáez, J.C. Review ISI SCOPUS Journal of Membrane Biology (2012)
Glial connexin expression and function in the context of Alzheimer's disease Koulakoff A.; Mei X.; Orellana J.A.; Sáez, J.C.; Giaume C. Review ISI SCOPUS Biochimica et Biophysica Acta - Biomembranes (2012)
Modulation of gap junction channels and hemichannels by growth factors Schalper K.A.; Riquelme, M. A.; Martinez A.D.; Vega, J. L.; Bennett, M. V. L.; Sáez, J.C. Review ISI SCOPUS Molecular BioSystems (2012)

Rommy von Bernhardi

Full Professor

Neurology

DEPT. NEUROLOGY, FAC. MEDICINE PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Felipe Simon

Profesor Titular

Department of Biological Sciences

UNIVERSIDAD ANDRES BELLO FAC DE CS BIOLOGICAS, DPTO DE CS BIOLOGICAS

Santiago, Chile

Agustin Martinez

Profesor Titular

Instituto de Neurociencia

UNIVERSIDAD DE VALPARAÍSO, CENTRO INTERDISCIPLINARIO DE NEUROCIENCIAS DE VALPARAÍSO

Valparaíso, Chile

FRANCISCO NUALART

Full Professor and Scientific Director

Cellular Biology and Center for Advanced Microscopy CMA BIO-BIO

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

María García

Profesor Titular

Biología Celular

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

Jimmy Stehberg

Associate Professor

Biological Sciences

UNIVERSIDAD ANDRÉS BELLO

SANTIAGO, Chile

PEDRO ZAMORANO

Profesor Asociado

Depto Biomédico

Universidad de Antofagasta

Antofagasta, Chile

Luis Cea

Profesor programa teaching

Instituto de Ciencias Biomédicas

Universidad Autónoma de Chile

Santiago, Chile

Juan Orellana

Associate Professor

Departamento de Neurología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Jose Luis Vega

Profesor Asociado

Biomedico

Universidad de Antofagasta

Antofagasta, Chile

Vania Figueroa

Directora InES Género y CTGénero, Coordinadora de Vinculación de Investigación Aplicada

Centro de Comunicación de las Ciencias

Universidad Autónoma de Chile

Santiago, Chile

Carlos Puebla

Assistant Professor

Universidad de O'Higgins

Santiago, Chile

Juan Sáez

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

César Echeverría

DIRECTOR DE INVESTIGACIÓN

Medicina

Universidad de Atacama

COPIAPO, Chile

Juan Saez

Professor

Instituto de Neurociencias

Universidad de Valparaiso

Valparaíso, Chile

Mauricio Retamal

Associate Professor

Programa de Comunicación Celular en Cancer

Universidad del Desarrollo

Santiago, Chile

Tomas Perez-Acle

Full Professor

Computational Biology Lab

Fundación Ciencia para la Vida

Santiago, Chile

Carlos Lagos

Profesor Asociado

FACULTAD DE MEDICINA Y CIENCIA

UNIVERSIDAD SAN SEBASTIÁN

SANTIAGO, Chile

Fernando Delgado

Associate Professor

Division of Medicine

Universidad Catolica del Maule

Talca, Chile

David Rovegno

PROFESOR ASISTENTE ADJUNTO

Medicina Intensiva

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

Rodrigo Acuña

Profesor Asistente Investigador

Medicina

Universidad del Desarrollo

Santiago, Chile

Marlene Arismendi

INVESTIGADOR JEFE

INVESTIGACION Y DESARROLLO

NANOTEC S.A

SANTIAGO, Chile

HELMUTH SANCHEZ

INVESTIGADOR ADJUNTO

Laboratorio de Conexinas y Panexinas

CENTRO INTERDISCIPLINARIO DE NEUROCIENCIAS DE VALPARAISO

VALPARAISO, Chile

Roberto Elizondo

Profesor Asistente

Departamento de Biología Celular

Universidad de Concepción

CONCEPCION, Chile

ISAAC GARCÍA

Profesor Adjunto

Instituto de Neurociencias

Universidad de Valparaiso

Valparaiso, Chile

Maria Ocaranza

Full Professor

Cardiovascular Diseases Division

Pontificia Universidad Catolica de Chile

Santiago, Chile

Carlos Puebla

Profesor Asistente

Universidad de O'Higgins

Rancagua, Chile

Daniela Salas

Aníbal Vargas

Investigador postdoctoral

Universidad Mayor

Santiago, Chile

Alvaro Becerra

Profesor Asociado

Ciencias Químico y Biológicas

Universidad Bernardo O'Higgins

Santiago, Chile

ROSALBA ESCAMILLA

Investigador asociado

Fisiología

Pontificia Universidad Católica de Chile

Santiago, Chile

PAOLA SOTO

Investigadora Laboratorio Fisiología Integrativa y Molecular

Facultad de Medicina

Universidad de Los Andes

Santiago, Chile

Iván Barría

Investigador Post doctoral

Centro Interdisciplinario de Neurociencia de Valparaíso

Valparaíso, Chile

Rodrigo Moraga

Investigador experto en Radiofarmacia preclínica

Merken Biotech SpA

Santiago , Chile

Juan Carlos Sáez Carreño

Líneas de Investigación

Article (23)

Abstract (2)

BookWhole (1)

Proyecto (2)

Review (8)