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ELISA IVANA BALBOA CASTILLO

Académico Investigador

Universidad Finis Terrae

SANTIAGO, Chile

Disfunción mitocondrial; Estrés Oxidativo; Enfermedad Neurodegenetariva, hígado graso no alcoholico, enfermedades raras, lisosoma, autofagia

Doctorado en Ciencias Médicas, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2015
Bioquímica, licenciatura en Bioquímica, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2009

Investigador para proyecto Fondecyt Regular 1141092 Part Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

santiago, Chile

2015 - 2016
académico investigador Full Time

UNIVERSIDAD FINIS TERRAE

medicina

santiago, Chile

2022 - A la fecha

alumna en practica

universidad de la frontera

Chile

2007 - 2007
bioquimico

pontificia universidad catolica de chile

Chile

2009 - 2010
tesista alumna de pregrado

pontificia universidad catolica de chile

Chile

2007 - 2009
Alumna Postgrado

pontificia universidad catolica de chile

Chile

2010 - 2015
personal tecnico

pontificia universidad catolica de chile

Chile

2009 - 2009
Docente Universidad San Sebastian Part Time

Universidad San Sebastián

Chile

2015 - 2016
Investigador Asociado Full Time

pontificia universidad catolica de chile

Chile

2015 - 2016

Buscar:


Genistein Activates Transcription Factor EB and Corrects Niemann-Pick C Phenotype Balboa, Elisa; Mattar, Pamela; Pulgar, Rodrigo Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Proteomic Analysis of Niemann-Pick Type C Hepatocytes Reveals Potential Therapeutic Targets for Liver Damage Balboa, Elisa; Marin, Tamara; Hardt, Robert; van den Bosch, Thea Article ISI CELLS (2021)
c-Abl Inhibition Activates TFEB and Promotes Cellular Clearance in a Lysosomal Disorder Heras, Macarena Las; Martinez, Alexis; Balboa, Elisa Article ISI ISCIENCE (2020)
Finding pathogenic commonalities between Niemann-Pick type C and other lysosomal storage disorders: Opportunities for shared therapeutic interventions Yanez, M. J.; Alvarez, A. R. Article ISI BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2020)
Vitamin E Blocks Connexin Hemichannels and Prevents Deleterious Effects of Glucocorticoid Treatment on Skeletal Muscles Balboa, Elisa; Regueira, Tomas Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
De novo expression of functional connexins 43 and 45 hemichannels increases sarcolemmal permeability of skeletal myofibers during endotoxemia Balboa, Elisa; Regueira, Tomas; Saez, Juan C Article ISI SCOPUS BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2019)
SEPSIS-INDUCED CHANNELOPATHY IN SKELETAL MUSCLES IS ASSOCIATED WITH EXPRESSION OF NON-SELECTIVE CHANNELS Vargas AA; Escamilla, R Article ISI Shock (2018)
Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C disease Torres, Sandra; Mat?as, Nuria; Baulies, Anna; Nu?ez, Susana; Alarcon-Vila, Cristina; Martinez, Laura; Nu?o, Natalia; Fernandez, Anna; Caballeria, Joan; Levade, Thierry; et al. Article ISI SCOPUS REDOX BIOLOGY (2017)
MLN64 induces mitochondrial dysfunction associated with increased mitochondrial cholesterol content Pinochet, Mar?a-Jos?; Mat?as, Nuria; Jos? S?ez, Pablo; Mart?nez, Alexis; ?lvarez, Alejandra R.; Garcia-Ruiz, Carmen; Fernandez-Checa, Jos? C. Article ISI SCOPUS REDOX BIOLOGY (2017)
Dexamethasone-induced muscular atrophy is mediated by functional expression of connexin-based hemichannels Vargas, An?bal A.; Escamilla, Rosalba; Regueira, Tom?s; S?ez, Juan C. Article ISI SCOPUS BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2016)
Spermatozoa from mice deficient in Niemann-Pick disease type C2 (NPC2) protein have defective cholesterol content and reduced in vitro fertilising ability Busso D, Oñate-Alvarado MJ, Balboa E, Castro J, Lizama C, Morales G, Vargas S, Härtel S, Moreno RD and S Zanlungo Article ISI SCOPUS REPRODUCTION FERTILITY AND DEVELOPMENT (2014)
Vitamin E Dietary Supplementation Improves Neurological Symptoms and Decreases c-Abl/p73 Activation in Niemann-Pick C Mice Marin, Tamara; Contreras, Pablo; Castro, Juan Francisco; Chamorro, David.; Balboa, Elisa; Bosch-Morató, Mònica; Muñoz, Francisco; Alvarez, Alejandra; Zanlungo, Silvana. Article ISI SCOPUS NUTRIENTS (2014)
Niemann-Pick C2 Protein Expression Regulates Lithogenic Diet-Induced Gallstone Formation and Dietary Cholesterol Metabolism in Mice Balboa E.; Morales G.; Aylwin, P; Carrasco, G; Amigo, L; Castro, J.; Rigotti, A.; Zanlungo S. Article ISI SCOPUS Lipids (2012)
Deficiency of Niemann-Pick C1 protein protects against diet-induced gallstone formation in mice Amigo, L; Balboa E.; Acuña M.; Castro, J.; Molina, H; Nervi, F; Rigotti, A.; Zanlungo S. Article ISI SCOPUS Liver International (2010)
Female infertility due to anovulation and defective steroidogenesis in NPC2 deficient mice Busso, D.; Onate-Alvarado, MJ; Balboa E.; Zanlungo S. Article ISI SCOPUS Molecular and Cellular Endocrinology (2010)

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Mitochondrial GSH resplenishment prevents progressive liver injury and extends life span in Niemann Pick Disease type C Matias, N; Balboa E.; Zanlungo S.; Levade, T; Garcia-Ruiz, C; Fernandez-Checa, J Abstract ISI HEPATOLOGY (2012)
Overexpression of MLN64 in hepatic cells induces mitochondrial dysfunction associated with increased transport of cholesterol into mitochondria Balboa E.; Pinochet, MJ; Matias, N; Fernandez-Checa, J; Zanlungo S. Abstract ISI HEPATOLOGY (2012)

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RELEVANCIA DEL ESTRÉS OXIDATIVO, LA DISFUNCIÓN MITOCONDRIAL Y LA EXPRESIÓN DE CONEXINAS EN LA INDUCCIÓN DE ATROFIA MUSCULAR POR DEXAMETASONA Proyecto (2016)
Connexin hemichannels as mediators of sarcolemmal and mitochondrial dysfunction in respiratory and peripheral muscle in the pathogenesis of sepsis associated-Intensive Care Unit Acquired Weakness (ICUAW) FONDECYT (1141092) Proyecto 2014-2018 Investigador(a)
RELEVANCE OF OXIDATIVE DAMAGE DUE TO MITOCHONDRIAL DYSFUNCTION AND/OR DECREASED ANTIOXIDANT DEFENSES IN THE PATHOGENESIS OF NIEMANN PICK TYPE C DISEASE FONDECYT (11103010) Proyecto 2011-2015 Tesista
RELEVANCIA DE LAS PROTEINAS NIEMANN PICK C EN FISIOLOGIA Y FISIOPATOLOGIA. FONDECYT (1070622) Proyecto 2007-2011 Tesista

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Lysosomal and Mitochondrial Liaisons in Niemann-Pick Disease Enrich, C; Fernandez-Checa, JC Review ISI SCOPUS FRONTIERS IN PHYSIOLOGY (2017)
Recent insights on the role of cholesterol in non-alcoholic fatty liver disease Arguello, G; Balboa E.; Arrese M.; Zanlungo S. Review ISI SCOPUS Biochimica et Biophysica Acta - Molecular Basis of Disease (2015)
Oxidative Stress: A Pathogenic Mechanism for Niemann-Pick Type C Disease Vazquez M.C.; Balboa E.; Zanlungo S. Review ISI SCOPUS OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2012)
Oxidative stress: a pathogenic mechanism for Niemann-Pick type C disease. Balboa E. Review SCOPUS OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2012)

MARCO ARRESE

FULL PROFESSOR

GASTROENTEROLOGY

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Juan Miquel

Full Professor

Gastroenterology

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

Alejandra Alvarez

Full professor

Cell and Molecular Biology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, FACULTAD DE CIENCIAS BIOLÓGICAS

Santiago, Chile

RICARDO MORENO

Profesor Titular

Fisiología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, FACULTAD DE CIENCIAS BIOLÓGICAS, DEPTO. DE FISIOLOGÍA

Santiago, Chile

Attilio Rigotti

Full Professor

Nutrition, Diabetes and Metabolism

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE - ESCUELA DE MEDICINA - DEPTO DE GASTROENTEROLOGÍA

Santiago, Chile

Luis Cea

Profesor programa teaching

Instituto de Ciencias Biomédicas

Universidad Autónoma de Chile

Santiago, Chile

Rodrigo Pulgar

Profesor/Investigador asistente

INTA

UNIVERSIDAD DE CHILE - INSTITUTO DE NUTRICION Y TECNOLOGIA DE ALIMENTOS

Santiago, Chile

Juan Saez

Professor

Instituto de Neurociencias

Universidad de Valparaiso

Valparaíso, Chile

Silvana Zanlungo

Full Professor

Gastroenterology

Pontificia Universidad Católica de Chile

Santiago, Chile

Attilio Rigotti

Full Professor

Nutrition, Diabetes and Metabolism

Pontificia Universidad Católica de Chile

Santiago, Chile

Dolores Busso

Associate Professor

Centro de Investigación e Innovación Biomédica

Universidad de Los Andes

Santiago, Chile

Mary Carmen Vázquez

Universidad San Sebastián

Santiago, Chile

ELISA BALBOA

Académico Investigador

Facultad de Medicina

Universidad Finis Terrae

SANTIAGO, Chile

GRACIELA ARGÜELLO

Académico

Universidad Católica del Maule

Curicó, Chile

Gonzalo Cancino

Assistant Professor

Faculty of Biological Sciences

Pontificia Universidad Católica de Chile

Santiago, Chile

Boris Rebolledo

Assistant Professor

Center for Genetics and Genomics

Universidad del Desarrollo

Santiago, Chile

Maria Yañez

Profesor Asistente

Universidad San Sebastián

Santiago, Chile

Carlos Puebla

Profesor Asistente

Universidad de O'Higgins

Rancagua, Chile

ANDRES KLEIN

Assistant Professor/Director (Head) Center for Genetics and Genomics; Director, PhD Program in Sciences and Innovation in Medicine

Centro de Genética y Genómica

Universidad del Desarrollo-Clínica Alemana

SANTIAGO, Chile

Tamara Marín

PhD en Ciencias médicas

Gastroenterología

Pontificia Universidad Católica de Chile

Santiago, Chile

Alexis Martinez

Investigador postdoctoral senior

Facultad de medicina

Instituto de Neurcoeincia Biomedica

Santiago, Chile

ROSALBA ESCAMILLA

Investigador asociado

Fisiología

Pontificia Universidad Católica de Chile

Santiago, Chile

PABLO TAPIA

Investigador postdoctoral

Centro de Biología Celular y Biomedicina (CEBICEM)

Universidad San Sebastián

Santiafgo, Chile

Macarena Las Heras

Investigadora postdoctoral

Facultad de Química y Biología

Universidad de Santiago de Chile

Santiago, Chile

ELISA IVANA BALBOA CASTILLO

Líneas de Investigación

Educación

Doctorado en Ciencias Médicas, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2015

Bioquímica, licenciatura en Bioquímica, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2009

Experiencia Académica

Investigador para proyecto Fondecyt Regular 1141092 Part Time

académico investigador Full Time

Experiencia Profesional

alumna en practica

bioquimico

tesista alumna de pregrado

Alumna Postgrado

personal tecnico

Docente Universidad San Sebastian Part Time

Investigador Asociado Full Time

Article (15)

Abstract (2)

Proyecto (4)

Connexin hemichannels as mediators of sarcolemmal and mitochondrial dysfunction in respiratory and peripheral muscle in the pathogenesis of sepsis associated-Intensive Care Unit Acquired Weakness (ICUAW)

RELEVANCE OF OXIDATIVE DAMAGE DUE TO MITOCHONDRIAL DYSFUNCTION AND/OR DECREASED ANTIOXIDANT DEFENSES IN THE PATHOGENESIS OF NIEMANN PICK TYPE C DISEASE

RELEVANCIA DE LAS PROTEINAS NIEMANN PICK C EN FISIOLOGIA Y FISIOPATOLOGIA.

Review (4)