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ELISA IVANA BALBOA CASTILLO

Académico Investigador

Universidad Finis Terrae

SANTIAGO, Chile

Líneas de Investigación


Disfunción mitocondrial; Estrés Oxidativo; Enfermedad Neurodegenetariva, hígado graso no alcoholico, enfermedades raras, lisosoma, autofagia

Educación

  •  Doctorado en Ciencias Médicas, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2015
  •  Bioquímica, licenciatura en Bioquímica, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2009

Experiencia Académica

  •   Investigador para proyecto Fondecyt Regular 1141092 Part Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    santiago, Chile

    2015 - 2016

  •   académico investigador Full Time

    UNIVERSIDAD FINIS TERRAE

    medicina

    santiago, Chile

    2022 - A la fecha

Experiencia Profesional

  •   alumna en practica

    universidad de la frontera

    Chile

    2007 - 2007

  •   bioquimico

    pontificia universidad catolica de chile

    Chile

    2009 - 2010

  •   tesista alumna de pregrado

    pontificia universidad catolica de chile

    Chile

    2007 - 2009

  •   Alumna Postgrado

    pontificia universidad catolica de chile

    Chile

    2010 - 2015

  •   personal tecnico

    pontificia universidad catolica de chile

    Chile

    2009 - 2009

  •   Docente Universidad San Sebastian Part Time

    Universidad San Sebastián

    Chile

    2015 - 2016

  •   Investigador Asociado Full Time

    pontificia universidad catolica de chile

    Chile

    2015 - 2016


 

Article (15)

Genistein Activates Transcription Factor EB and Corrects Niemann-Pick C Phenotype
Proteomic Analysis of Niemann-Pick Type C Hepatocytes Reveals Potential Therapeutic Targets for Liver Damage
c-Abl Inhibition Activates TFEB and Promotes Cellular Clearance in a Lysosomal Disorder
Finding pathogenic commonalities between Niemann-Pick type C and other lysosomal storage disorders: Opportunities for shared therapeutic interventions
Vitamin E Blocks Connexin Hemichannels and Prevents Deleterious Effects of Glucocorticoid Treatment on Skeletal Muscles
De novo expression of functional connexins 43 and 45 hemichannels increases sarcolemmal permeability of skeletal myofibers during endotoxemia
SEPSIS-INDUCED CHANNELOPATHY IN SKELETAL MUSCLES IS ASSOCIATED WITH EXPRESSION OF NON-SELECTIVE CHANNELS
Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C disease
MLN64 induces mitochondrial dysfunction associated with increased mitochondrial cholesterol content
Dexamethasone-induced muscular atrophy is mediated by functional expression of connexin-based hemichannels
Spermatozoa from mice deficient in Niemann-Pick disease type C2 (NPC2) protein have defective cholesterol content and reduced in vitro fertilising ability
Vitamin E Dietary Supplementation Improves Neurological Symptoms and Decreases c-Abl/p73 Activation in Niemann-Pick C Mice
Niemann-Pick C2 Protein Expression Regulates Lithogenic Diet-Induced Gallstone Formation and Dietary Cholesterol Metabolism in Mice
Deficiency of Niemann-Pick C1 protein protects against diet-induced gallstone formation in mice
Female infertility due to anovulation and defective steroidogenesis in NPC2 deficient mice

Abstract (2)

Mitochondrial GSH resplenishment prevents progressive liver injury and extends life span in Niemann Pick Disease type C
Overexpression of MLN64 in hepatic cells induces mitochondrial dysfunction associated with increased transport of cholesterol into mitochondria

Proyecto (4)

RELEVANCIA DEL ESTRÉS OXIDATIVO, LA DISFUNCIÓN MITOCONDRIAL Y LA EXPRESIÓN DE CONEXINAS EN LA INDUCCIÓN DE ATROFIA MUSCULAR POR DEXAMETASONA
Connexin hemichannels as mediators of sarcolemmal and mitochondrial dysfunction in respiratory and peripheral muscle in the pathogenesis of sepsis associated-Intensive Care Unit Acquired Weakness (ICUAW)
RELEVANCE OF OXIDATIVE DAMAGE DUE TO MITOCHONDRIAL DYSFUNCTION AND/OR DECREASED ANTIOXIDANT DEFENSES IN THE PATHOGENESIS OF NIEMANN PICK TYPE C DISEASE
RELEVANCIA DE LAS PROTEINAS NIEMANN PICK C EN FISIOLOGIA Y FISIOPATOLOGIA.

Review (4)

Lysosomal and Mitochondrial Liaisons in Niemann-Pick Disease
Recent insights on the role of cholesterol in non-alcoholic fatty liver disease
Oxidative Stress: A Pathogenic Mechanism for Niemann-Pick Type C Disease
Oxidative stress: a pathogenic mechanism for Niemann-Pick type C disease.
22
ELISA BALBOA

Académico Investigador

Facultad de Medicina

Universidad Finis Terrae

SANTIAGO, Chile

12
Silvana Zanlungo

Full Professor

Gastroenterology

Pontificia Universidad Católica de Chile

Santiago, Chile

5
Alejandra Alvarez

Full professor

Cell and Molecular Biology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, FACULTAD DE CIENCIAS BIOLÓGICAS

Santiago, Chile

4
Juan Miquel

Full Professor

Gastroenterology

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

4
Dolores Busso

Associate Professor

Centro de Investigación e Innovación Biomédica

Universidad de Los Andes

Santiago, Chile

3
ROSALBA ESCAMILLA

Investigador asociado

Fisiología

Pontificia Universidad Católica de Chile

Santiago, Chile

3
Attilio Rigotti

Full Professor

Nutrition, Diabetes and Metabolism

Pontificia Universidad Católica de Chile

Santiago, Chile

3
Attilio Rigotti

Full Professor

Nutrition, Diabetes and Metabolism

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE - ESCUELA DE MEDICINA - DEPTO DE GASTROENTEROLOGÍA

Santiago, Chile

3
Luis Cea

Profesor programa teaching

Instituto de Ciencias Biomédicas

Universidad Autónoma de Chile

Santiago, Chile

2
PABLO TAPIA

Investigador postdoctoral

Centro de Biología Celular y Biomedicina (CEBICEM)

Universidad San Sebastián

Santiafgo, Chile

2
Carlos Puebla

Profesor Asistente

Universidad de O'Higgins

Rancagua, Chile

2
ANDRES KLEIN

Assistant Professor/Director (Head) Center for Genetics and Genomics; Director, PhD Program in Sciences and Innovation in Medicine

Centro de Genética y Genómica

Universidad del Desarrollo-Clínica Alemana

SANTIAGO, Chile

2
GRACIELA ARGÜELLO

Académico

Universidad Católica del Maule

Curicó, Chile

2
Juan Saez

Professor

Instituto de Neurociencias

Universidad de Valparaiso

Valparaíso, Chile

1
Tamara Marín

PhD en Ciencias médicas

Gastroenterología

Pontificia Universidad Católica de Chile

Santiago, Chile

1
MARCO ARRESE

FULL PROFESSOR

GASTROENTEROLOGY

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Mary Carmen Vázquez

Universidad San Sebastián

Santiago, Chile

1
RICARDO MORENO

Profesor Titular

Fisiología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, FACULTAD DE CIENCIAS BIOLÓGICAS, DEPTO. DE FISIOLOGÍA

Santiago, Chile

1
Rodrigo Pulgar

Profesor/Investigador asistente

INTA

UNIVERSIDAD DE CHILE - INSTITUTO DE NUTRICION Y TECNOLOGIA DE ALIMENTOS

Santiago, Chile

1
Gonzalo Cancino

Assistant Professor

Facultad de Ciencias

Universidad Mayor

Santiago, Chile