Man

Alejandra Beatriz Alvarez Rojas

Full professor

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, FACULTAD DE CIENCIAS BIOLÓGICAS

Santiago, Chile

Líneas de Investigación


My research line is focused on understanding the molecular mechanisms involved in neurodegenerative diseases. Our results support a key role of dysregulated c-Abl signaling in Alzheimer and Niemann Pick diseases.

Educación

  •  Biochemistry, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1989
  •  Cell and Molecular Biology, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1998

Experiencia Académica

  •   Researcher Part Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Santiago, Chile

    2016 - A la fecha

  •   Researcher Part Time

    Basal Center for Aging and Regeneration CARE CHILE UC

    Biological Sciences

    Santiago, Chile

    2013 - Sin Información

  •   Cloister member Other

    UNIVERSIDAD DE CHILE

    Santiago, Chile

    2012 - A la fecha

  •   Chief of PhD program Other

    Cell and Molecular Biology PhD program

    Biological Sciences

    Santiago, Chile

    2010 - 2014

  •   Associate Professor Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Biological Sciences

    Santiago, Chile

    2010 - 2016

  •   Cloister member. Cell and Molecular Biology PhD program. Other

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Biological Sciences

    Santiago, Chile

    2002 - A la fecha

  •   Assistant Professor Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Biological Sciences

    Santiago, Chile

    2002 - 2010

  •   Research in Formation Biochemical Cytology Laboratory Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Biological Sciences

    Santiago, Chile

    1990 - 1991

  •   Postdoctorate Full Time

    UNIVERSIDAD DE CHILE

    Sciences Faculty

    Santiago, Chile

    1998 - 2000

  •   Full Professor Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Biological Sciences

    Santiago, Chile

    2017 - A la fecha

Experiencia Profesional

  •   Researcher Part Time

    Center of the Nanotechnology and advanced Materials CIEN UC

    Santiago, Chile

    2016 - A la fecha

  •   Researcher Part Time

    Basal Center for Aging and Regeneration CARE CHILE UC

    Santiago, Chile

    2013 - A la fecha

  •   Director Part Time

    Chilean FONDEF D10E1077, Preclinical studies of new inhibitors of c-Abl kinase for the treatment of Alzheimer's disease

    Santiago, Chile

    2017 - A la fecha

  •   co-Investigator Other

    Chilean Redes 150082, LysosHead: Lysosomes signaling in health and disease. PI Silvana Zanlungo

    Santiago, Chile

    2016 - A la fecha

  •   Research Associate Full Time

    FONDAP-BIOMEDICINA UC

    Santiago, Chile

    2000 - 2002

  •   Director Part Time

    FONDEF D10I1077 Identification of inhibitors of c-Abl kinase for the potential treatment of Alzheimer's Disease

    Santiago, Chile

    2011 - 2014

Formación de Capital Humano


Formación de Capital humano

CURSOS COLECTIVOS DE PREGRADO:
2003-2008 Docente (colaborador) Biología de la Célula. Para Bioquímica, Licenciatura en Ciencias Biológicas y Agronomía.
2005-2008 Docente (a cargo) Biología de la Célula para Química y Farmacia.
2009-2016 Docente (a cargo) Laboratorio de Bioquímica y Biología Celular de la Licenciatura en Ciencias.
2009-presente Colaborador en: Cursos de Biología de la Célula y Patología Molecular para alumnos de Bioquímica, Licenciatura en Ciencias Biológicas y Medicina
2017-2020 Docente (a cargo) Biología de la Célula para Química y Farmacia.
2020-presente Docente (a cargo) Biología Celular Avanzada. Para Bioquímica, Licenciado en Ciencias Biológicas.
2021- Docente (a cargo) Biología de la Célula el College de Matemáticas y Ciencias exactas.
2002-presente, Cada año varias unidades de investigación de un semestre para estudiantes de licenciatura en Biología y Bioquímica.
CURSOS COLECTIVOS DE POSTGRADO:
2002-presente, Docente (colaborador) Curso de Biología Celular (BIO444A)
2008-presente, Docente (a cargo) Curso Vías de señalización en enfermedades neurodegenerativas (BIO-4104)
2012-actualidad Docente (colaborador) Bases Celulares y Moleculares de Neurobiología (BIO4103)

DIRECCIÓN DE TESIS
Tesis de pregrado finalizadas: 15 (Licenciatura en Ciencias Biológicas y Bioquímica), Tesis de Magister finalizadas: 3, Tesis de Doctorado, (16 finalizadas, 4 en curso)
DOCTORES (TESIS FINALIZADAS)
1. Abril del 2008 - Mary Carmen Vázquez. Programa de Doctorado en Biología Celular y Molecular. Facultad de Ciencias Biológicas, P. Universidad Católica de Chile. La c-Abl quinasa modula la actividad AICD en presencia de la proteína adaptadora FE65 (Director Dr. Alvarez, codirector Dr. Inestrosa).
2. Junio del 2009 - Andres Klein. Programa de doctorado en Biología Celular y Molecular. Facultad de Ciencias Biológicas, P. Universidad Católica de Chile. Vía de transducción de señales c-Abl / p73 en la enfermedad de Niemann-Pick tipo C (Directora Dra. Silvana Zanlungo, codirectora Dra. Alvarez).
3. Septiembre del 2009 - Ignacio Cancino Lobos. Programa de doctorado en Biología Celular y Molecular. Facultad de Ciencias Biológicas, P. Universidad Católica de Chile. La tirosina quinasa c-Abl en la enfermedad de Alzheimer: su papel en la muerte neuronal y alteraciones del citoesqueleto.
4. Enero del 2010 - Karen G. Pérez de Arce. Programa de doctorado en Biología Celular y Molecular. Facultad de Ciencias Biológicas, P. Universidad Católica de Chile. La tirosina quinasa c-Abl regula la acumulación sináptica de PSD-95 y modula el número de contactos sinápticos con las neuronas del hipocampo.
5. Julio del 2010 - Veronica Codelia. Programa de doctorado en Biología Celular y Molecular. Facultad de Ciencias Biológicas, P. Universidad Católica de Chile. Función dual de la proteína p73 durante la espermatogénesis: efectos en la diferenciación y apoptosis.
6. Julio del 2010 - Lisbell Estrada A. Programa de Doctorado en Ciencias Biológicas, Facultad de Ciencias, Universidad de Chile. Semillas de oligómeros, nuevas estrategias para el diagnóstico de Alzheimer y posibles implicaciones para la progresión de la enfermedad (Director Dr. Claudio Soto, codirector Dr. Alvarez).
7. Junio del 2011 - Lina Vargas Rojas. Programa de doctorado en Biología Celular y Molecular. Facultad de Ciencias Biológicas, P. Universidad Católica de Chile. La señalización del receptor de efrina A4 / c-Abl quinasa media la sinaptotoxicidad de los oligómeros A?.
8. Septiembre del 2014 - Marcelo González. Programa de doctorado en Biología Celular y Molecular. Facultad de Ciencias Biológicas, P. Universidad Católica de Chile. c-Abl induce la fosforilación de tirosina HDAC2 y la represión de genes neuronales en modelos de enfermedades de Alzheimer.
9. Enero del 2016 - Maria Jose Yañez. Programa de doctorado en Biología Celular y Molecular. Facultad de Ciencias Biológicas, P. Universidad Católica de Chile. La tirosina quinasa c-Abl modula el procesamiento de la proteína precursora amiloide y su implicancia para Niemann Pick Tipo C. (Directora Dra. Alvarez, codirectora Dra. Silvana Zanlungo).
10. Noviembre del 2016 - Alexis Martínez Saavedra. Programa de doctorado en Biología Celular y Molecular. Facultad de Ciencias Biológicas, P. Universidad Católica de Chile. La cinasa C-Abl fosforila la mitofusina-2 modulando la dinámica mitocondrial y la apoptosis; papel potencial de c-Abl en la esclerosis lateral amiotrófica.
11. Agosto del 2017 - Francisco Morales Zavala. Programa de Doctorado en Bioquímica, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile. Nanopartículas de oro modificadas con péptidos: Biodistribución y efectos sobre la agregación de ?-amiloide. (Director Marcelo Kogan, codirector Dr. Alvarez).
12. Enero del 2019 - Pablo Contreras. Programa de Doctorado en Biología Celular y Molecular. Facultad de Ciencias Biológicas, P. Universidad Católica de Chile. La inhibición de la tirosina quinasa Abl activa el TFEB y promueve el aclaramiento celular en la enfermedad de Niemann-Pick C. (Director Dr. Alvarez, codirector Dra. Silvana Zanlungo).
13. Diciembre del 2019 - Adrián González. Programa de doctorado en Biología Celular y Molecular. Facultad de Ciencias Biológicas, P. Universidad Católica de Chile. La ausencia de tirosina quinasa Abl1 promueve la expresión de genes sinápticos y promueve la memoria y el aprendizaje.
14. Junio del 2020 - Fabián Montecino Morales. Programa de doctorado en Biología Celular y Molecular. Facultad de Ciencias Biológicas, P. Universidad Católica de Chile. Función de las tirosina quinasa no receptora de Abelson 1 durante la miogénesis de precursores musculares adultos. (Director Hugo Olguín, codirector Dr. Alvarez).
15. Abril del 2020 - Tamara Marín. Programa de Doctorado en Ciencias Médicas, Facultad de Medicina, P. Universidad Católica de Chile. c-Abl quinasa en la enfermedad de Niemann Pick tipo A: su implicancia en los mecanismos patogénicos que conducen a alteraciones del flujo autofágico y neurodegeneración. Directora Dra. Silvana Zanlungo, codirectora Dra. Alvarez)
16. Noviembre de 2020 - Rilda León. Programa de Doctorado en Neurociencias, Facultad de Medicina, P. Universidad Católica de Chile. La c-Abl quinasa contribuye al deterioro cognitivo de los ratones transgénicos con enfermedad de Alzheimer.

POSTDOCTORADOS
1. 2005 Julio Amigo (Doctor en Biología Celular y Molecular y Neurociencias, Facultad de Ciencias, U Chile).
2. 2007-2008 Lorena Varela (Doctora en Biología Celular y Molecular, Facultad de Ciencias Biológicas PUC, FONDECYT-Postdoctorado 3070017).
3. 2007-2008 codirectora Carola Maldonado (Doctora en Ciencias Químicas y Farmacéuticas, UCH).
4. 2010-2012 Lisbell Estrada (Doctora en Biología Celular, Facultad de Ciencias, U. FONDECYT-Postdoctorado 3110052).
5. 2011-2013 Lina Vargas Rojas (Doctora en Biología Celular y Molecular, Facultad de Ciencias Biológicas PUC. Postdoctorado FONDECYT 33120015).
6. 2017 Ignacio Cancino (Doctor en Biología Celular y Molecular, Facultad de Ciencias Biológicas PUC).
7. 2019 Pablo Tapia (Doctor en Genética y Microbiología Molecular, Facultad de Ciencias Biológicas PUC).


Premios y Distinciones

  •   Alvarez Alejandra

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Chile, 1985

    Undergraduate “Honor Student Award”, PUC for the best Biochemist student 1985

  •   Alvarez Alejandra

    COMISION NACIONAL DE INVESTIGACION CIENTIFICA Y TECNOLOGICA

    Chile, 1992

    Graduate scholarship

  •   Alvarez Alejandra

    FUNDACION CIENCIA PARA LA VIDA

    Chile, 1998

    Best Ph.D Thesis 1998

  •   Alvarez Alejandra and Zanlungo Silvana

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Chile, 2008

    Best Patent presented 2008

  •   Inestrosa Nibaldo, Alvarez Alejandra

    The FEBS Journal

    Chile, 2008

    2008 Top-cited Paper Award The FEBS Journal


 

Article (67)

c-Abl activates RIPK3 signaling in Gaucher disease
c-Abl kinase kinase is required for satellite cell function through Pax7 regulation
Amyloid Beta-Peptide Increases BACE1 Translation through the Phosphorylation of the Eukaryotic Initiation Factor-2 alpha
c-Abl Inhibition Activates TFEB and Promotes Cellular Clearance in a Lysosomal Disorder
Finding pathogenic commonalities between Niemann-Pick type C and other lysosomal storage disorders: Opportunities for shared therapeutic interventions
Genotoxic stress triggers the activation of IRE1 alpha-dependent RNA decay to modulate the DNA damage response
Gold Nanoparticles Mediate Improved Detection of beta-amyloid Aggregates by Fluorescence
Study of nitrogen implantation in Ti surface using plasma immersion ion implantation & deposition technique as biocompatible substrate for artificial membranes.
The Protein Tyrosine Phosphatase Receptor Delta Regulates Developmental Neurogenesis
c-Abl Deficiency Provides Synaptic Resiliency Against A beta-Oligomers
Human Albumin Impairs Amyloid beta-peptide Fibrillation Through its C-terminus: From docking Modeling to Protection Against Neurotoxicity in Alzheimer's disease
Amyloid-beta oligomers synaptotoxicity: The emerging role of EphA4/c-Abl signaling in Alzheimers disease
Functionalization of stable fluorescent nanodiamonds towards reliable detection of biomarkers for Alzheimers disease
MLN64 induces mitochondrial dysfunction associated with increased mitochondrial cholesterol content
Peptide multifunctionalized gold nanorods decrease toxicity of beta-amyloid peptide in a Caenorhabditis elegans model of Alzheimer's disease
c-Abl links APP-BACE1 interaction promoting APP amyloidogenic processing in Niemann-Pick type C disease
Glutamatergic stimulation induces GluN2B translation by the nitric oxide-Heme-Regulated eIF2? kinase in cortical neurons
Neuronal gene repression in Niemann-Pick type C models is mediated by the c-Abl/HDAC2 signaling pathway
Reduction of Blood Amyloid-? Oligomers in Alzheimer?s Disease Transgenic Mice by c-Abl Kinase Inhibition
Anti-Ribosomal P Protein Autoantibodies From Patients With Neuropsychiatric Lupus Impair Memory in Mice
Characterizing HSF1 Binding and Post-Translational Modifications of hsp70 Promoter in Cultured Cortical Neurons: Implications in the Heat-Shock Response
Physiological Control of Nitric Oxide in Neuronal BACE1 Translation by Heme-Regulated eIF2 alpha Kinase HRI Induces Synaptogenesis
Reactive oxygen species trigger motoneuron death in non-cell-autonomous models of ALS through activation of c-Abl signaling
c-Abl Stabilizes HDAC2 Levels by Tyrosine Phosphorylation Repressing Neuronal Gene Expression in Alzheimer's Disease
EphA4 Activation of c-Abl Mediates Synaptic Loss and LTP Blockade Caused by Amyloid-beta Oligomers
The unique case of the Niemann-Pick type C cholesterol storage disorder
Vitamin E Dietary Supplementation Improves Neurological Symptoms and Decreases c-Abl/p73 Activation in Niemann-Pick C Mice
Cholinergic Abnormalities, Endosomal Alterations and Up-Regulation of Nerve Growth Factor Signaling in Niemann-Pick Type C Disease
Increased copper levels in in vitro and in vivo models of Niemann-Pick C disease
Lysosomal vitamin E accumulation in Niemann-Pick type C disease
c-Abl tyrosine kinase modulates tau pathology and Cdk5 phosphorylation in AD transgenic mice
C-Abl Tyrosine Kinase Signaling: A New Player in AD Tau Pathology
Corticotropin-releasing factor binding protein enters the regulated secretory pathway in neuroendocrine cells and cortical neurons
Lack of Activation of the Unfolded Protein Response in Mouse and Cellular Models of Niemann-Pick Type C Disease
Oxidative stress activates the c-Abl/p73 proapoptotic pathway in Niemann-Pick type C neurons
Tetrahydrohyperforin prevents cognitive deficit, Abeta deposition, tau phosphorylation and synaptotoxicity in the APPswe/PSEN1deltaE9 model of Alzheimer's disease: a possible effect on APP processing.
p73 participates in male germ cells apoptosis induced by etoposide
Synaptic Clustering of PSD-95 Is Regulated by c-Abl through Tyrosine Phosphorylation
c-Abl Modulates AICD Dependent Cellular Responses: Transcriptional Induction and Apoptosis
Role of the Wnt receptor Frizzled-1 in presynaptic differentiation and function
Heparin activates Wnt signaling for neuronal morphogenesis
Imatinib therapy blocks cerebellar apoptosis and improves neurological symptoms in a mouse model of Niemann-Pick type C disease
STI571 prevents apoptosis, tau phosphorylation and behavioural impairments induced by Alzheimer's beta-amyloid deposits
Overexpression of the cholesterol-binding protein MLN64 induces liver damage in the mouse.
Acetylcholinesterase-amyloid-beta-peptide interaction: effect of Congo Red and the role of the Wnt pathway.
Activation of the neuronal c-Abl tyrosine kinase by amyloid-beta-peptide and reactive oxygen species.
Wnt-3a overcomes beta-amyloid toxicity in rat hippocampal neurons.
Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by beta-amyloid fibrils.
Protein kinase C inhibits amyloid beta peptide neurotoxicity by acting on members of the Wnt pathway.
Wnt signaling involvement in beta-amyloid-dependent neurodegeneration.
A cdk5-p35 stable complex is involved in the beta-amyloid-induced deregulation of cdk5 activity in hippocampal neurons
Acetylcholinesterase-amyloid-beta-peptide interaction and Wnt signaling involvement in Abeta neurotoxicity.
Increase in the expression of the neuronal cyclin-dependent protein kinase cdk-5 during differentiation of N2A neuroblastoma cells.
Inhibition of tau phosphorylating protein kinase cdk5 prevents beta-amyloid-induced neuronal death.
Molecular modeling of the amyloid-beta-peptide using the homology to a fragment of triosephosphate isomerase that forms amyloid in vitro.
Regulatory roles of microtubule-associated proteins in neuronal morphogenesis. Involvement of the extracellular matrix.
Brain acetylcholinesterase promotes amyloid-beta-peptide aggregation but does not hydrolyze amyloid precursor protein peptides.
Laminin blocks the assembly of wild-type A beta and the Dutch variant peptide into Alzheimer's fibrils.
Stable complexes involving acetylcholinesterase and amyloid-beta peptide change the biochemical properties of the enzyme and increase the neurotoxicity of Alzheimer's fibrils.
A monoclonal antibody against acetylcholinesterase inhibits the formation of amyloid fibrils induced by the enzyme.
Acetylcholinesterase promotes the aggregation of amyloid-beta-peptide fragments by forming a complex with the growing fibrils.
Acetylcholinesterase accelerates assembly of amyloid-beta-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme.
Acetylcholinesterase is a senile plaque component that promotes assembly of amyloid beta-peptide into Alzheimer’s filaments
Laminin inhibits amyloid-beta-peptide fibrillation.
Acetylcholinesterase, a senile plaque component, affects the fibrillogenesis of amyloid-beta-peptides.
Characterization of human peroxisomal membrane proteins.
Isolation of peroxisomes from frozen human liver samples.

ConferencePaper (1)

Alzheimer's beta-amyloid deposits induce the c-Abl/p73 signaling in AD models.

EditorialMaterial (1)

P73 and P63: The siblings that work together in neurodevelopment

Proyecto (34)

The antagonistic functions of PTPRD and ABL1 during the development of the embryonic cortex and its implications in neurodevelopmental disorders
Versatile NIR-responsive nanosystems to improve detection and for photothermal disaggregation of beta amyloid
ABL kinases at the crossroads of healthy synaptic remodeling and synaptic dysfunction in in vitro excitotoxiciy and in vivo temporal lobe Epilepsy.
Discovery of a Novel TFEB Regulation Pathway by the c-Abl Kinase Reveals a Common Therapeutic Approach for Sphingolipidosis
Lipids and Synaptic Signaling in Health and Disease
Preclinical studies of new inhibitors of c-Abl kinase for the treatment of Alzheimer's disease
Gold nanoparticles multifunctionalized with peptides to improve detection and to obtain disaggregation of beta-amyloid.
c-Abl is a key cellular and synaptic homeostasis regulator. Its dysregulation is involved in the early Alzheimer disease
The impact of the tyrosine phosphatase PTPRD on neural stem cell biology and its contribution to autism spectrum disorder etiology
The synaptic c-Abl kinase regulates synaptic plasticity in adult brain. Its dysregulation is involved in synaptic loss in Alzheimer Disease.
Activation of the c-Abl kinase via the EphA4 receptor induces the synaptic incorporation of the NMDA-NR2A / PSD95 complex
Identification of inhibitors of c-Abl kinase for the potential treatment of Alzheimer's Disease
Relevance of oxidative damage due to mitochondrial dysfunction and/or decreased antioxidant defenses in the pathogenesis of Niemann Pick type C disease
Uncovering the mechanisms of amyloid clearance induced by STI571-treatment in Alzheimer’s disease: the role of the c-Abl kinase.
Alteration of the neuronal cytoskeleton and loss of synapse in neurodegeneration: Function of the c-Abl / p73 signaling pathway
Effect of the non-canonical Wnt pathway on the assembly and differentiation of the postsynaptic apparatus in hippocampal neurons; Possible connection with c-Abl kinase
Relevance of the Niemann pick C proteins in physiology and pathophysiology
Semi-synthetic drug IDN 5706 for the treatment of Alzheimer's disease and cognitive disorders
The proapoptotic c-Abl kinase as a therapeutic target for Niemann pick type C disease
Signalling pathways leading to neuronal death in NPC: finding new therapeutics targets
Apoptosis in Neurodegeneration: Function of c-Abl kinase and p73 protein, possible modulating effect of ApoER2
Genesis of Helical Paired Strands (PHF) in Alzheimer's Disease
Induction of β-amyloid peptide aggregation by acetylcholinesterase
Characterization of Peroxisomal membrane proteins
Center for Aging and Regeneration (CARE)
GNF-2/GNF-5 chemical derivatives for the treatment of Alzheimer disease
Inflammation, a key element in neurodegenerative processes: Activation of c-Abl kinase in aging in a murine Alzheimer model
LysosHead: Lysosomes Signaling in Health and Disease
Nano-devices for high-precision measurements in biology and nanostructured materials of biomedical interest
Nilotinib promotes TFEB translocation to the nucleus: A new therapeutic strategy for Niemann-Pick C disease
Participation of Abl / Arg kinases in the neurodegeneration of Alzheimer's disease
Project. Porins of S. Typhi
Searching for Common Pathogenic Pathways leading to Neuronal and Hepatic Damage in Niemann-Pick Diseases Role
Structural and functional study of the brain of mice with Niemann Pick disease type C

Review (3)

Lysosome motility and distribution: Relevance in health and disease
Oxidative Stress: A Pathogenic Mechanism for Niemann-Pick Type C Disease
Amyloid-cholinesterase interactions - Implications for Alzheimer's disease
83
Alejandra Alvarez

Full professor

Cell and Molecular Biology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, FACULTAD DE CIENCIAS BIOLÓGICAS

Santiago, Chile

20
Silvana Zanlungo

Full Professor

Gastroenterology

Pontificia Universidad Católica de Chile

Santiago, Chile

10
Nibaldo Inestrosa

Full Professor

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

8
ANDRES KLEIN

Assistant Professor/Director (Head) Center for Genetics and Genomics; Director, PhD Program in Sciences and Innovation in Medicine

Centro de Genética y Genómica

Universidad del Desarrollo-Clínica Alemana

SANTIAGO, Chile

6
Gonzalo Cancino

Assistant Professor

Facultad de Ciencias

Universidad Mayor

Santiago, Chile

4
Ivan Alfaro

Associate Professor, Director of Innovation and Technology Development

Faculty of Medicine

Universidad del Desarrollo

Santiago, Chile

4
Katia Gysling

Professor

Cellular and Molecular Biology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

3
Francisco Morales

Posdoctoral

Universidad de Chile. Centro FONDAP ACCDiS

Santiago, Chile

3
lisbell estrada

Decana Facultad Ciencias de la Salud

Facultad de Ciencias de la Salud

Universidad Bernardo O Higgins

santiago, Chile

2
Lorena Varela

Assistant Professor

Biological Sciences

Universidad Andres Bello

Santiago, Chile

2
Mary Carmen Vázquez

Universidad San Sebastián

Santiago, Chile

2
Francisca Bronfman

Full Professor

Instituto de Ciencias Biomédicas

Universidad Andrés Bello

Santiago, Chile

2
Tamara Marín

PhD en Ciencias médicas

Gastroenterología

Pontificia Universidad Católica de Chile

Santiago, Chile

2
Maria Andres

Full Professor

Cellular and Molecular Biology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

2
Rommy von Bernhardi

Full Professor

Neurology

DEPT. NEUROLOGY, FAC. MEDICINE PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

2
Enrique Brandan

Profesor Titular

Biología Celular y Molecular

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

2
Fanny Guzman

Investigador Senior

Núcleo de Biotecnología Curauma

Pontificia Universidad Católica de Valparaiso

Valparaiso, Chile

1
Natalia Hassan

Coordinadora

Universidad Tecnológica Metropolitana

Santiago, Chile

1
Waldo Cerpa

Profesor Asociado

Biología Celular y Molecular

Pontificia Universidad Catolica de Chile

Santiago, Chile

1
Nathalie Casanova

profesor asociado

artes liberales

Universidad Adolfo Ibañez

Santiago, Chile

1
Simon Guerrero

Investigador

Instituto de Investigación Interdisciplinar en Ciencias Biomédicas SEK

Universidad SEK

Santiago, Chile

1
Maria-Isabel Yuseff

Associate Professor

Cellular and Molecular Biology

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Rebeca Aldunate

Profesor Titular

Ciencias

UNIVERSIDAD SANTO TOMÁS

Santiago, Chile

1
Eyleen Araya

Academic

Chemical Sciences

Universidad Andres Bello

santiago, Chile

1
Ana Riveros

Profesor Asistente

Departamento de Química Farmacológica y Toxicológica

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS QUIMICAS Y FARMACÉUTICAS

Santiago, Chile

1
Alicia Nogueras

Profesor Asociado Adjunto

Departamento de Biología Celular y Molecular

P. UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Mario Favre

Profesor Titular

Instituto de Física, Pontificia Universidad Católica de Chile

Santiago, Chile

1
Jeronimo Maze

Associate Professor

Physics

FACULTAD DE FISICA, PONTIFICIA UNIVERSIDAD CATOLICA

Santiago, Chile

1
Fabián Segovia

Assistant professor

Department of Cell Biology

Universidad de Concepción

Concepción, Chile

1
Francisca Cornejo

Postdoc

Universidad Mayor

Santiago, Chile

1
Nicole Cortés

Coordinadora de Estudios Clínicos

Laboratorio de Biología Celular, Molecular y Neurociencias, Corporación Centro Internacional de Biomedicina, ICC

Santiago, Chile

1
RICARDO MORENO

Profesor Titular

Fisiología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, FACULTAD DE CIENCIAS BIOLÓGICAS, DEPTO. DE FISIOLOGÍA

Santiago, Chile

1
Felipe Court

Full Professor and Director

Center for Integrative Biology

Universidad Mayor

Huechuraba, Chile

1
Alvaro Elorza

ASSOCIATE PROFESSOR

INSTITUTE OF BIOMEDICAL SCIENCES

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

1
Andrea Gómez

Investigador Postdoctoral

Fisiología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Lina Vargas

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Luis González

Full Professor

School of Medicine

Universidad San Sebastián

Santiago, Chile

1
JUAN PABLO HENRIQUEZ

Associate Professor

Cell Biology

UNIVERSIDAD DE CONCEPCIÓN, FACULTAD DE CIENCIAS BIOLÓGICAS, DEPARTAMENTO DE BIOLOGÍA CELULAR

Concepción, Chile

1
Patricia Burgos

Associate Professor Programa de Doctorado en Biología Celular y Biomedicina CEBICEM

UNIVERSIDAD SAN SEBASTIÁN

Santiago, Chile

1
Christian Gonzalez

Full Professor

Biology

Universidad de Chile

Santiago, Chile

1
Julio Amigo

Assistant Professor

Physiology

Pontificia Universidad Catolica de Chile

Santiago, Chile

1
FREDDY CELIS

Profesor Asociado

Química

Universidad de Playa Ancha

Valparaiso, Chile

1
Mauricio Gonzalez

Profesor Titular

INTA

UNIVERSIDAD DE CHILE - INSTITUTO DE NUTRICION Y TECNOLOGIA DE ALIMENTOS

Santiago, Chile

1
Oscar Lazo

Research Fellow

UK Dementia Research Institute and Department of Neuromuscular diseases

UCL Queen Square Institute of Neurology

London, Reino Unido

1
Monica Soler

Associate Professor

Chemical Engineering, Biotechnology and Materials

University of Chile

Santiago, Chile

1
Marcelo Kogan

Academico

Quimica Farmacologica y Toxicologica

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

1
DENISSE SEPULVEDA

Postdoc

Universidad Mayor de Chile

Santiago, Chile

1
ADRIAN GONZALEZ

Postdoc

Biologia celular

Pontificia Universidad Católica de Chile

Santiago de Chile, Chile

1
Philippe Pihán

Posdoctorado

Fisiología

Universidad de Chile

Santiago, Chile

1
Juan Oyarzún

Investigador postdoctoral

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Claudio Hetz

Deputy Director

INSTITUTO DE CIENCIAS BIOMÉDICAS, FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

SANTIAGO, Chile