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Oscar Marcelo Lazo Jerez

Research Fellow

UCL Queen Square Institute of Neurology

London, Reino Unido

Líneas de Investigación


Tráfico y señalización de receptores de neurotrofinas; Neuroplasticidad en el sistema nervioso adulto; Regulación de la morfología y complejidad neuronal; Regeneración en el sistema nervioso central; Enfermedades neurodegenerativas.

Educación

  •  Ciencias Biológicas, Fisiología, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2011
  •  Ciencias Biológicas, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2007
  •  Licenciatura en Ciencias Biológicas, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2006

Experiencia Académica

  •   Investigador Postdoctoral Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Ciencias Biológicas

    Santiago, Chile

    2011 - 2013

  •   Profesor Adjunto Other

    UNIVERSIDAD ANDRES BELLO

    Ciencias Sociales

    Santiago, Chile

    2013 - 2016

  •   Newton International Fellow Full Time

    UNIVERSITY COLLEGE LONDON

    Brain Sciences

    London, Reino Unido

    2016 - 2018

  •   Research Fellow Full Time

    UNIVERSITY COLLEGE LONDON

    Brain Sciences

    London, Reino Unido

    2019 - A la fecha


 

Article (9)

Venlafaxine treatment after endothelin-1-induced cortical stroke modulates growth factor expression and reduces tissue damage in rats
Spatiotemporal intracellular dynamics of neurotrophin and its receptors. Implications for neurotrophin signaling and neuronal function
The p75 neurotrophin receptor evades the endolysosomal route in neuronal cells, favouring multivesicular bodies specialised for exosomal release.
BDNF regulates Rab11-mediated recycling endosome dynamics to induce dendritic branching.
Cholinergic Abnormalities, Endosomal Alterations and Up-Regulation of Nerve Growth Factor Signaling in Niemann-Pick Type C Disease
Cholinergic abnormalities, endosomal alterations and up-regulation of Nerve Growth Factor signaling in Niemann-Pick type C disease.
An agonistic mAb directed to the TrkC receptor juxtamembrane region defines a trophic hot spot and interactions with p75 coreceptors.
Axotomy-induced neurotrophic withdrawal causes loss of phenotypic differentiation and downregulation of NGF signaling, but not death of septal cholinergic neurons.
Spatiotemporal intracellular dynamics of neurotrophin and its receptors. Implications for neurotrophin signaling and neuronal function.
3
Oscar Lazo

Research Fellow

UK Dementia Research Institute and Department of Neuromuscular diseases

UCL Queen Square Institute of Neurology

London, Reino Unido

2
Silvana Zanlungo

Full Professor

Gastroenterology

Pontificia Universidad Católica de Chile

Santiago, Chile

2
Francisca Bronfman

Full Professor

Instituto de Ciencias Biomédicas

Universidad Andrés Bello

Santiago, Chile

1
ANDRES KLEIN

Assistant Professor/Director (Head) Center for Genetics and Genomics; Director, PhD Program in Sciences and Innovation in Medicine

Centro de Genética y Genómica

Universidad del Desarrollo-Clínica Alemana

SANTIAGO, Chile

1
Nibaldo Inestrosa

Full Professor

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Christian Gonzalez

Full Professor

Biology

Universidad de Chile

Santiago, Chile

1
Gareth Owen

Profesor Titular

Fisiologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Alejandra Alvarez

Full professor

Cell and Molecular Biology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, FACULTAD DE CIENCIAS BIOLÓGICAS

Santiago, Chile