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Sebastián Dante Calligaris

Cordinador de Estudios Clínicos

Clínica Alemana

Santiago, Chile

Mi labor como investigador está enfocada en: 1-desarrollar nuevos tratamientos en base a células madre mesenquimáticas o por sus derivados (medios condicionados) para enfermedades cardiovasculares (inducidas por antraciclinas) y 2- desarrollar nuevos métodos de diagnóstico precoz (por microRNAs) para enfermedades cardiovasculares con desarrollo "silencioso" que tienen relevancia en la práctica clínica después de un episodio de infarto agudo de miocardio. Cardio-protective effect of conditioned medium from Adipose-derived mesenchymal stem cell in a cardiomyopathy induced by anthracycline animal model. Identification of miRNAs involved in the patogenesis of diabetic cardiomyopathy.

Licenciado en Biotecnología, Universidad Nacional de Rosario. Argentina, 2001
Doctor en Ciencias Biomoleculares, Università degli Studi di Trieste. Italia, 2007

Profesor asistente Jornada Parcial

Universidad del Desarrollo

Santiago, Chile

2013 - Sin Información

Investigador

Universidad del Desarrollo

Santiago, Chile

2009 - Sin Información


Circulating miR-19b and miR-181b are potential biomarkers for diabetic cardiomyopathy Copier, CU Article ISI SCOPUS SCIENTIFIC REPORTS (2017)
Multipotent mesenchymal stromal cells: A promising strategy to manage alcoholic liver disease Ezquer, F; Bruna F.; Calligaris, S; Conget P.; Ezquer, M Article ISI SCOPUS WORLD JOURNAL OF GASTROENTEROLOGY (2016)
Rab24 interacts with the Rab7/Rab interacting lysosomal protein complex to regulate endosomal degradation Militello, RD Article ISI SCOPUS TRAFFIC (2016)
Cardiac stress test induced by dobutamine and monitored by cardiac catheterization in mice. Ricca M.; Conget P. Article ISI SCOPUS JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2013)
Intravenous administration of bone marrow-derived multipotent mesenchymal stromal cells has a neutral effect on obesity-induced diabetic cardiomyopathy Calligaris, Sebastián D; Conget, Paulette Article ISI SCIELO SCOPUS Biological Research (2013)
Mice Long-Term High-Fat Diet Feeding Recapitulates Human Cardiovascular Alterations: An Animal Model to Study the Early Phases of Diabetic Cardiomyopathy Calligaris, SD; Lecanda M; Solis, F; Ezquer, M; Gutierrez J.; Brandan, E.; Leiva A.; Sobrevia L.; Conget P. Article ISI SCOPUS PLOS ONE (2013)


Two complementary strategies to improve cell engraftment in mesenchymal stem cell-based therapy: Increasing transplanted cell resistance and increasing tissue receptivity Review ISI SCOPUS CELL ADHESION & MIGRATION (2017)
Subclinical Detection of Diabetic Cardiomyopathy with MicroRNAs: Challenges and Perspectives Leon, LE; Rani, S; Fernandez, M.; Larico, M; Calligaris, SD Review ISI SCOPUS JOURNAL OF DIABETES RESEARCH (2016)
Mesenchymal stem cell therapy for doxorubicin cardiomyopathy: hopes and fears Ezquer, F; Gutierrez J.; Ezquer, M; Caglevic, C; Salgado, HC; Calligaris, SD Review ISI SCOPUS Stem Cell Research and Therapy (2015)