Man

Luis Edgardo Leon Paredes

Head of Bioinformatics and Computational Biology

PhageLab

Santiago, Chile

Líneas de Investigación


Genomics, bioinformatics, microbiome, human genetics

Educación

  •  Licenciatura en Bioquímica, Universidad de Santiago de Chile. Chile, 2006
  •  Magister, Pontifica Universidad Católica de Chile. Chile, 2009
  •  Bioquímico, Universidad de Santiago de Chile. Chile, 2006
  •  Doctor, Pontifica Universidad Católica de Chile. Chile, 2013

 

Article (9)

A novel sequencing-based vaginal health assay combining self-sampling, HPV detection and genotyping, STI detection, and vaginal microbiome analysis

Bik, Elisabeth M.; Bird, Sara W.; Bustamante, Juan P.; Leon, Luis E.; Nieto, Pamela A.; Addae, Kwasi; Alegria-Mera, Victor; Bravo, Cristian; Bravo, Denisse; Cardenas, Juan P.; Carson, Glenn A.; Caughey, Adam; Covarrubias, Paulo C.; Perez-Donoso, Jose; Gass, Graham; Gupta, Sarah L.; Harman, Kira; Hongo, Donna Marie B.; Jimenez, Juan C.; Kraal, Laurens; Melis-Arcos, Felipe; Morales, Eduardo H; Morton, Amanda; Navas, Camila F.; Nunez, Harold; Olivares, Eduardo; Ordenes-Aenishanslins, Nicolas; Ossandon, Francisco J.; Phan, Richard; Pino, Raul; Soto-Liebe, Katia; Varas, Ignacio; Vera-Wolf, Patricia; Walton, Nathaniel A.; Almonacid, Daniel E.; Goddard, Audrey D.; Ugalde, Juan A.; Zneimer, Susan; Richman, Jessica; Apte, Zachary S.

Article ISI
PLOS ONE  (2019)

Association between phenotype and deletion size in 22q11.2 microdeletion syndrome: systematic review and meta-analysis

Fernanda Rozas, M.; Benavides, Felipe; Leon, Luis; Repetto, Gabriela M.

Article ISI SCOPUS
ORPHANET JOURNAL OF RARE DISEASES  (2019)

Deletions in Genes Participating in Innate Immune Response Modify the Clinical Course of Andes Orthohantavirus Infection

Esteves Ribeiro, Grazielle; Edgardo Leon, Luis; Perez, Ruth; Cuiza, Analia; Agustin Vial, Pablo; Ferres, Marcela; Mertz, Gregory J.; ; Vial, Cecilia

Article ISI SCOPUS
VIRUSES-BASEL  (2019)

Circulating miR-19b and miR-181b are potential biomarkers for diabetic cardiomyopathy

Copier, CU; Leon, L; Fernandez, M; Contador, D; Calligaris, SD

Article ISI SCOPUS
SCIENTIFIC REPORTS  (2017)

Partial microduplication in the histone acetyltransferase complex member KANSL1 is associated with congenital heart defects in 22q11.2 microdeletion syndrome patients

León L.E.; Benavides F.; Espinoza K.; Vial C.; Alvarez P.; Palomares M.; Lay-Son G.; Miranda M.; Repetto G.M.

Article ISI SCOPUS
Scientific Reports  (2017)

Perspectivas actuales sobre el diagnóstico genómico en pediatría

Lay-Son, R. Guillermo; León, P. Luis

Article SCIELO
REVISTA CHILENA DE PEDIATRIA  (2015)

Opening of pannexin- and con nexin-based channels increases the excitability of nodose ganglion sensory neurons

Retamal, Mauricio A; Alcayaga, Julio; Verdugo, Christian A.; Bultynck, Geert; Leybaert, Luc; Sáez, Pablo J.; Fernández, Ricardo; León, Luis E.; Sáez, Juan C.

Article ISI
FRONTIERS IN CELLULAR NEUROSCIENCE  (2014)

Activities of steroid metabolic enzymes in secretory endometria from untreated women with Polycystic Ovary Syndrome

Leon, L.; Bacallao, K; Gabler F.; Romero C.; Valladares, L; Vega M.

Article ISI SCOPUS
STEROIDS  (2008)

In situ estrogen metabolism in proliferative endometria from untreated women with polycystic ovarian syndrome with and without endometrial hyperplasia

Bacallao, K; Leon, L.; Gabler F.; Soto, E; Romero C.; Valladares, L; Vega M.

Article ISI SCOPUS
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY  (2008)

BookWhole (1)

Visualization and Analysis of MiRNA-Targets Interactions Networks

León L.E.; Calligaris S.D.

BookWhole ISI SCOPUS
NEISSERIA MENINGITIDIS  (2017)

Review (1)

Subclinical Detection of Diabetic Cardiomyopathy with MicroRNAs: Challenges and Perspectives

Leon, LE; Rani, S; Fernandez, M. ; Larico, M; Calligaris, SD

Review ISI SCOPUS
JOURNAL OF DIABETES RESEARCH  (2016)

11
Luis Leon

Head of Bioinformatics and Computational Biology

Technology

PhageLab

Santiago, Chile

2
Guillermo Lay-Son

PROFESOR ASISTENTE

CENTRO DE GENÉTICA Y GENÓMICA

UNIVERSIDAD DEL DESARROLLO

Santiago, Chile

2
Carmen Romero

Jefe Laboratorio Endocrinología y Biología Reproductiva

Obstetricia y Ginecología

HOSPITAL CLÍNICO UNIVERSIDAD DE CHILE

Santiago, Chile

2
Maria Vega

Academico Profesora Titular

Obstetricia y Ginecologia Campus Norte

UNIVERSIDAD DE CHILE - FACULTAD DE MEDICINA

Santiago, Chile

2
Sebastián Calligaris

Cordinador de Estudios Clínicos

Clínica Alemana

Santiago, Chile

2
Mauricio Fernandez

medico staff

Cardiologia

Clinica Alemana de Santiago

santiago, Chile

2
Maria Repetto

Profesor Titular

Center for Genetics and Genomics

FACULTAD DE MEDICINA CLINICA ALEMANA-UNIVERSIDAD DEL DESARROLLO

Santiago, Chile

2
Maria Vial

Associate Professor/Profesor Asociado

Instituto de Ciencias e Innovación de Medicina

UNIVERSIDAD DEL DESARROLLO

Santiago, Chile

1
Juan Cardenas

Assistant Professor

Universidad Mayor de Chile

Santiago, Chile

1
Paulo Covarrubias

Profesional

Genética Molecular

Instituto de Salud Pública

Santiago, Chile

1
Juan Ugalde

Assistant Professor

Facultad de Ciencias de la Vida

Universidad Andrés Bello

Santiago, Chile

1
Marcela Ferres

Head of Department

Pediatric Infectious Diseases and Immunology

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Denisse Bravo

Associate Professor

Pathology and Oral Medicine

UNIVERSIDAD DE CHILE

Santiago, Chile

1
CRISTIAN BRAVO

Profesional

Laboratorio Biomédico

Instituto Salud Publica

Santiago, Chile

1
Grazielle Ribeiro

PhD candidate

Medicina

Universidad del Desarrollo- UDD

Santiago, Chile

1
Katia Soto

Académica

Universidad de Chile

Santiago, Chile

1
Juan Saez

Professor

Instituto de Neurociencias

Universidad de Valparaiso

Valparaíso, Chile

1
David Contador

Professor Instructor

School of Medicine

Universidad del Desarrollo

Santiago, Chile

1
Pablo Vial

Professor

School of Medicine

ICIM/UNIVERSIDAD DEL DESARROLLO - CLÍNICA ALEMANA

Santiago, Chile

1
Julio Alcayaga

Profesor Titular

Biología

UNIVERSIDAD DE CHILE, FAC. CIENCIAS, DEPTO. BIOLOGÍA

Santiago, Chile

1
Mauricio Retamal

Associate Professor

Centro de Fisiología Celular e Integrativa

Universidad del Desarrollo

Santiago, Chile

1
Ricardo Fernández

Associate Professor

Salud

Universidad de Los Lagos

Osorno, Chile

1
Karena Espinoza

Directora

Centro Asistencial Docente e Investigación

Universidad de Magallanes

Punta Arenas, Chile

1
Juan Jiménez

Investigador I+D Senior

Multiplex SpA

Santiago, Chile