Man

Denisse Margarita Bravo Rodriguez

Associate Professor

UNIVERSIDAD DE CHILE

Santiago, Chile

Líneas de Investigación


Molecular mechanisms of oral and gastrointestinal bacterial interaction with host cells. Control mechanisms of oral bacteria

Educación

  •  Biochemist, Universidad de Chile. Chile, 2009
  •  Biochemist, UNIVERSIDAD DE CHILE. Chile, 2003

Experiencia Académica

  •   Assistant Professor Full Time

    UNIVERSIDAD DE CHILE

    Dentistry

    Santiago, Chile

    2011 - A la fecha

  •   Associate Professor Full Time

    UNIVERSIDAD DE CHILE

    Dentistry

    Santiago, Chile

    2011 - 2019

Experiencia Profesional

  •   Postdoctoral Full Time

    Universidad de Chile

    Santiago, Chile

    2009 - 2010

Formación de Capital Humano


Developing Thesis
1) PhD in Pharmacology, Universidad de Chile. Leonor Díaz Velis. (Advisor Dr. Jorge Gamonal, Co-advisor Denisse Bravo)
2) PhD in Pharmacology, Universidad de Chile. Jimena Canales Urriola. (Advisor Dr. Dr. Andrew Quest, Co-advisor Denisse Bravo)
3) Master in Biochemist, Universidad de Chile. Cristopher Soto López. (Advisor Denisse Bravo)

Finished Thesis
1) Undergraduate, Biochemist, Universidad de Santiago. Samantha Gonzales Quiñonez. (Advisor Denisse Bravo)
2) Undergraduate, Biochemist, Universidad de Chile. Ignacio Lobos Matthei. (Advisor Denisse Bravo)
3) Undergraduate, Dentist, Universidad de Chile. IIsaac Bugueño. (Advisor Denisse Bravo)
4) Master in Biochemist, Universidad de Chile. Daniel Plaza. (Advisor Dr. J.M. Pérez-Donoso, Co-advisor Denisse Bravo)
5) Undergraduate, Biotechnology, Universidad Andrés Bello. Diana Schofield. (Advisor Dr. J.M. Pérez-Donoso, Co-advisor Denisse Bravo)

Academic Experience
Postgraduate
2012-2013 Master in Dentistry Science. Faculty of Dentistry, Universidad de Chile

Undergraduate
2011-2014. Professor of "Microbiology and Oral Microbiology". Faculty of Dentistry. Universidad de Chile.
Professor of "Methodology of Investigation". Faculty of Dentistry. Universidad de Chile.
2010. Professor of "Microbiology". Technologic Faculty. Universidad de Santiago de Chile.
Professor of "Microbiology". Technologic Faculty. Universidad de Santiago de Chile.
Professor of "Molecular Biology". Faculty of Biological Science. Universidad Andrés Bello.
Professor of "Biochemist". Faculty of Biological Science. Universidad Andrés Bello.
2006-2010. Professor of "Microbiology". Faculty of Biological Science. Universidad Andrés Bello.


Premios y Distinciones

  •   Selected for participation in “64th Meetings of the Laureates”

    ACADEMIA CHILENA DE CIENCIAS

    Alemania, 2014

    Selection for participation in the 64th Meetings of the Nobel Laureates

  •   "FUTURO EN INVESTIGACIÓN"

    COLGATE PALMOLIVE CHILE S.A

    Chile, 2013

    Award to the most original investigation in the International Association of Dental Research (IADR) Chilean division

  •   Best Oral presentation

    SOCIEDAD CHILENA DE GASTROENTEROLOGIA

    Chile, 2012

    Best Oral presentation in the XXXIV meeting of gastroenterology

  •   Best Poster Presentation

    Asociación Latinoamericana de Microbiología (ALAM)

    Brasil, 2010

    Best Poster presentation in the XIX Latin-American Congress of Microbiology

  •   Oriana Josseau

    UNIVERSIDAD DE CHILE

    Chile, 2009

    Best PhD student

  •   Best oral communication

    ASOCIACION CHILENA DE MICROBIOLOGIA

    Chile

    Best oral presentation in the XXVII national meeting of SOMICH

  •   best student in clinical biochemistry

    Laboratorios Roche

    Chile, 2003

    best student in clinical biochemistry course

  •   undergraduate researcher student

    INSTITUTO MILENIO DE ESTUDIOS AVANZADOS EN BIOLOGIA CELULAR Y BIOTECNOLOGIA

    Chile, 2002

    Award to the best young undergraduate researcher

  •   Premio por el mejor trabajo presentado

    IADR división Chile

    Chile, 2020

    Premio por el trabajo presentado en la XXXII Reunión Anual de la International Association of Dental Research (IADR) división Chilena.


 

Article (31)

A novel sequencing-based vaginal health assay combining self-sampling, HPV detection and genotyping, STI detection, and vaginal microbiome analysis
Biological Synthesis of CdS/CdSe Core/Shell Nanoparticles and Its Application in Quantum Dot Sensitized Solar Cells
Synthesis of salt-stable fluorescent nanoparticles (quantum dots) by polyextremophile halophilic bacteria
Variability in Genomic and Virulent Properties of Porphyromonas gingivalis Strains Isolated From Healthy and Severe Chronic Periodontitis Individuals
Arsenic and Cadmium Bioremediation by Antarctic Bacteria Capable of Biosynthesizing CdS Fluorescent Nanoparticles
Phosphate Favors the Biosynthesis of CdS Quantum Dots in Acidithiobacillus thiooxidans ATCC 19703 by Improving Metal Uptake and Tolerance
Helicobacter pylori Induced Phosphatidylinositol-3-OH Kinase/mTOR Activation Increases Hypoxia Inducible Factor-1a to Promote Loss of Cyclin D1 and G0/G1 Cell Cycle Arrest in Human Gastric Cells.
Isolation and Characterization of Phenanthrene Degrading Bacteria from Diesel Fuel-Contaminated Antarctic Soils
Biological synthesis of fluorescent nanoparticles by cadmium and tellurite resistant Antarctic bacteria: Exploring novel natural nanofactories
The Porphyromonas gingivalis O antigen is required for inhibition of apoptosis in gingival epithelial cells following bacterial infection.
The Porphyromonas gingivalis O antigen is required for inhibition of apoptosis in gingival epithelial cells following bacterial infection.
Changes in lipopolysaccharide profile of Porphyromonas gingivalis clinical isolates correlate with changes in colony morphology and polymyxin B resistance
Enhanced caveolin-1 expression increases migration, anchorage-independent growth and invasion of endometrial adenocarcinoma cells
Host response mechanisms in periodontal diseases
Characterization of the Arginine Decarboxylase Gene (ORF HP0422, speA) Involved in Acid Tolerance in Helicobacter pylori
Low-temperature biosynthesis of fluorescent semiconductor nanoparticles (CdS) by oxidative stress resistant Antarctic bacteria
Microarray analysis of the Escherichia coli response to CdTe-GSH Quantum Dots: understanding the bacterial toxicity of semiconductor nanoparticles
Quantum dot-based assay for Cu2+ quantification in bacterial cell culture
Use of titanium dioxide nanoparticles biosynthesized by Bacillus mycoides in quantum dot sensitized solar cells
Designing antimicrobial bioactive glass materials with embedded metal ions synthesized by the sol-gel method
Helicobacter pylori-Induced Loss of Survivin and Gastric Cell Viability Is Attributable to Secreted Bacterial Gamma-Glutamyl Transpeptidase Activity
Surface characterization of GSH-CdTe quantum dots
Biomimetic, Mild Chemical Synthesis of CdTe-GSH Quantum Dots with Improved Biocompatibility
Enhanced Glutathione Content Allows the In Vivo Synthesis of Fluorescent CdTe Nanoparticles by Escherichia coli
Spectroscopic Properties and Biocompatibility Studies of CdTe Quantum Dots Capped with Biological Thiols
The normal chain length distribution of the O antigen is required for the interaction of Shigella flexneri 2a with polarized Caco-2 cells
Different sugar residues of the lipopolysaccharide outer core are required for early interactions of Salmonella enterica serovars Typhi and Typhimurium with epithelial cells
Type IVB pili are required for invasion but not for adhesion of Salmonella enterica serovar Typhi into BHK epithelial cells in a cystic fibrosis transmembrane conductance regulator-independent manner
Helicobacter pylori-Induced Loss of the Inhibitor-of-Apoptosis Protein Survivin Is Linked to Gastritis and Death of Human Gastric Cells
Growth-phase regulation of lipopolysaccharide O-antigen chain length influences serum resistance in serovars of Salmonella
The outer core lipopolysaccharide of Salmonella enterica Serovar typhi is required for bacterial entry into epithelial cells

BookSection (2)

Bioremediating heavy metals through the synthesis of metal nanoparticles by microorganisms
Bioremediating heavy metals through the synthesis of metal nanoparticles by microorganisms.

Proyecto (11)

Determination of critical genes encoding virulence factors of P. gingivalis involved in the onset and progression of periodontitis=> new insights on the transition from health to disease
ENDODONTIC PATHOGEN-INDUCED MACROPHAGE RESPONSIVENESS PROFILES AND THEIR EPIGENETIC REGULATION AS DETERMINANTS FOR SYSTEMIC INFLAMMATION AND TREATMENT RESPONSE IN CHRONIC APICAL PERIODONTITIS
THE IMPORTANCE OF SULFUR AND PHOSPHATE METABOLISM ON THE BIOSYNTHESIS AND PROPERTIES OF COPPER AND LITHIUM NANOPARTICLES PRODUCED BY BACTERIA.
ROLE OF PERIODONTO-PATHOGENIC BACTERIAL SEROTYPES IN PROMOTING THE ALVEOLAR BONE RESORPTION DURING PERIODONTITIS THROUGH AN IMBALANCE OF TH1/TH 17 VERSUS TREG IMMUNE RESPONSES
Nanotecnología para Aplicaciones Biomédicas (NanoBioMat)
Señalización por estrés metabólico en cáncer, enfermedades cardiovasculares y diabetes
CROSSTALK BETWEEN LOCAL HOST RESPONSE TO ENDODONTIC INFECTION AND LOW-GRADE SYSTEMIC INFLAMMATION IN ASYMPTOMATIC APICAL PERIODONTITIS=> PROSPECTIVE STUDY EVALUATING THE EFFECT OF CONSERVATIVE ENDODONTIC TREATMENT
"ROLE OF P. GINGIVALIS LPS IN PROMOTING PERSISTENCE IN GINGIVAL EPITHELIAL CELLS AND PROGRESSION OF CHRONIC PERIODONTITIS BY UPREGULATION OF SURVIVIN"
Aislamiento de microorganismos Antárticos capaces de sintetizar nanopartículas semiconductoras altamente fluorescentes (quantum dots) para aplicaciones biotecnologicas
Papel del LPS de P. gingivalis en la persistencia en células epiteliales gingivales y la progresión de la periodontitis crónica mediada por el aumento de survivina
Role of P. gingivalis LPS in promoting persistence in gingival epithelial cells and progression of chronic periodontitis by upregulation of survivin
27
Denisse Bravo

Associate Professor

Pathology and Oral Medicine

UNIVERSIDAD DE CHILE

Santiago, Chile

8
José Pérez

Associate Professor

Biologia

Universidad Andres Bello

Santiago, Chile

7
Anilei Hoare

Profesora Asistente

Medicina y Patología Oral

Universidad de Chile

SANTIAGO, Chile

4
Victor Diaz

Profesional

Universidad San Sebastian

Concención, Chile

4
Igor Osorio

Académico

Instituto de Ciencias Químicas

Universidad Austral de Chile

Valdivia , Chile

4
Claudio Vasquez

Full Professor

Biology Department

UNIVERSIDAD DE SANTIAGO DE CHILE

Santago, Chile

3
ALEJANDRO CORVALAN

Associate Professor

Hematology and Oncology

Pontificia Universidad Catolica de Chile

Santiago, Chile

3
Sergio Álvarez

Profesor Asistente

Bioquímica y Biología Molecular

UNIVERSIDAD DE CHILE. FACULTAD DE CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

2
oscar almarza

Universidad Mayor

Santiago, Chile

2
Jorge Gamonal

Académico

Odontología Conservadora

FACULTAD DE ODONTOLOGÍA, UNIVERSIDAD DE CHILE

Santiago, Chile

2
Nicolás Dutzan

Associate Professor

Facultad de Odontología

Universidad de Chile

Santiago, Chile

2
Carlos Blondel

Profesor Asistente

Instituto de Ciencias Biomédicas

Universidad Andrés Bello

Santiago, Chile

2
Lisette Leyton

Full Professor

Cell and Molecular Biology

FACULTAD DE MEDICINA UNIVERSIDAD DE CHILE

Santiago, Chile

2
Mario Diaz

Profesor asistente

Instituto Ciencias odontológicas

UNIVERSIDAD DE CHILE FACULTAD DE ODONTOLOGIA

Santiago, Chile

1
IVAN CALDERON

Associate Professor / Academic Coordinator / Principal Investigator

Biological Sciences

UNIVERSIDAD ANDRÉS BELLO

SANTIAGO, Chile

1
Juan Cardenas

Assistant Professor

Universidad Mayor de Chile

Santiago, Chile

1
CRISTIAN BRAVO

Profesional

Laboratorio Biomédico

Instituto Salud Publica

Santiago, Chile

1
Gareth Owen

Profesor Titular

Fisiologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Juan Ugalde

Assistant Professor

Facultad de Ciencias de la Vida

Universidad Andrés Bello

Santiago, Chile

1
Hernán Huerta

Asistente de Investigación

Centro de Biología Integrativa

Universidad Mayor de Chile

Santiago, Chile

1
Roberto Molina

Investigador Científico

Biología

Centro de Estudios Científicos

Valdivia, Chile

1
Luis Leon

Director of Bioinformatics

R&D

Genoma Mayor SpA

Santiago, Chile

1
Hery Urra

Staff scientist

INSTITUTO DE NEUROCIENCIA BIOMEDICA (BNI)

Santiago, Chile

1
Julian Bejarano

Investigador Postdoctoral

Universidad de Chile. Centro FONDAP ACCDiS

Santiago, Chile

1
Eduardo Castro

Professor

Departamento de Microbiología

Universidad de Talca

Talca, Chile

1
Juan Gautier

profesor titular

Química de los materiales

Universidad de Santiago de Chile

Santiago, Chile

1
Emma Hernandez

Académico 44 h, profesor titular

Oral Patology and Medicine

Universidad de Chile, Facultad de Odontología

SANTIAGO, Chile

1
Rolando Vernal

Profesor Titular

Departamento de Odontología Conservadora

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Loreto Abusleme

Assistant Professor

Oral pathology and medicine

FACULTAD DE ODONTOLOGÍA, UNIVERSIDAD DE CHILE

Santiago, Chile

1
Carmen Romero

Jefe Laboratorio Endocrinología y Biología Reproductiva

Obstetricia y Ginecología

HOSPITAL CLÍNICO UNIVERSIDAD DE CHILE

Santiago, Chile

1
Maria Vega

Academico Profesora Titular

Obstetricia y Ginecologia Campus Norte

UNIVERSIDAD DE CHILE - FACULTAD DE MEDICINA

Santiago, Chile

1
Soledad Henriquez

Profesor Asistente

INSTITUTO DE INVESTIGACIONES MATERNO INFANTIL, FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

1
Carolina Quezada

Postdoctoral researcher

CIBQA

Universidad Bernardo O'Higgins

Santiago, Chile

1
Cecilia Silva

Investigador Principal

Biologia

Centro de Estudios Cientificos

Valdivia, Chile

1
Claudio Meneses

Profesor Asociado

Facultad de Agronomía e Ingeniería Forestal/ Facultad de Ciencias Biológicas

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Oscar Cerda

Associate Professor

Molecular and Cellular Biology

Universidad de Chile

Santiago, Chile

1
Sarita Soto

Asistente de Investigación

Facultad de Odontología

Universidad de Chile

Santiago, Chile

1
Humberto Palza

Associate Professor

Departamento de Ingeniería Química y Biotecnología

Universidad de Chile

Santiago, Chile

1
Andrew Quest

Full Professor

Biologia Celular y Molecular

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

1
Paulina Calderón

Investigador Principal

Biome Therapeutics

Santiago, Chile

1
Paulo Covarrubias

Profesional

Genética Molecular

Instituto de Salud Pública

Santiago, Chile

1
Katia Soto

Académica

Universidad de Chile

Santiago, Chile

1
Rodrigo Espinoza

Associate Professor

Department of Chemical Engineering Biotechnology and Materials

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Carla Gallardo

PhD

Departamento de Ciencias Químicas y Recursos Naturales

Universidad de La Frontera

Temuco, Chile

1
Juan Jiménez

Investigador I+D Senior

Multiplex SpA

Santiago, Chile