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Eduardo Felipe Castro Nallar

Associate Professor

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

Líneas de Investigación


Microbial Ecology; Metagenomics; High-Throughput Sequencing; Bioinformatics and Computational Biology; Population Genetics and Evolution

Educación

  •  Science and Humanities, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 2001
  •  Biochemistry, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 2006
  •  PhD in Biological Sciences, GEORGE WASHINGTON UNIVERSITY. Estados Unidos, 2015
  •  Biochemistry, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 2007

Experiencia Académica

  •   Associate Professor Full Time

    UNIVERSIDAD ANDRES BELLO

    Facultad de Ciencias de la Vida

    Santiago, Chile

    2015 - A la fecha

  •   Adjunct Researcher Part Time

    GEORGE WASHINGTON UNIVERSITY

    Milken School of Public Health

    Washington, DC, Estados Unidos

    2016 - A la fecha

Experiencia Profesional

  •   Teaching Assistant

    Brigham Young University

    Estados Unidos

    2011 - 2011

  •   Jefe de Laboratorio

    Diagnotec

    Chile

    2007 - 2009

  •   Asistente de investigación

    Universidad de Chile

    Chile

    2007 - 2007

  •   Teaching Assistant

    Brigham Young University

    Estados Unidos

    2012 - 2012

  •   Tesista pregrado

    Universidad de Santiago de Chile

    Chile

    2006 - 2006

  •   Chief Science Officer

    Aperiomics

    Estados Unidos

    2014 - 2015

  •   Consultor

    Ictiobiotech

    Chile

    2014 - 2015

  •   Profesor Investigador

    Universidad Andrés Bello

    Chile

    2015 - A la fecha

Formación de Capital Humano


I lead a research lab at the Center for Bioinformatics and Integrative Biology of Universidad Andrés Bello since July 2015, with molecular and computational space. Currently, the people at the lab includes two postdoctoral researchers (funded by FONDECYT and UC Davis Chile), three PhD candidates (two funded by UNAB and One by CONICYT), one master’s and one undergraduate student, plus a full-time research assistant. To the date, I have one successful graduate student: Daniel Tichy obtained his master degree in biotechnology at Universidad Andrés Bello, early this year. The lab has also been able to attract foreign talent in the form of 3 interns at the masters and bachelors levels (France, USA, and The Netherlands) who are participating in at least 3 publications.


Difusión y Transferencia


I actively participate with PAR Explora O’Higgins in matters related to evaluating, assisting and sponsoring high school students and teachers with their research projects for the “Feria Científica Escolar”. I also work with NGOs such as Innovacien where students can do internships in his laboratory and have a real-life experience into scientific research. Plus, I taught three workshops in (meta)genomics and data analysis in R software in Chile (Santiago and Antofagasta) and Perú (Arequipa) and Bangladesh.


Premios y Distinciones

  •   Technological internships: Identification and Detection tools for Fish Alphaviruses.

    CORPORACION DE FOMENTO DE LA PRODUCCION

    Chile, 2009

    Grant code 09PTEC-5241. Grant awarded by Corporation to the Promotion of Production (Corfo, www.corfo.cl).

  •   Bicentennial Fellowship for International PhD studies.

    COMISION NACIONAL DE INVESTIGACION CIENTIFICA Y TECNOLOGICA

    Chile, 2009

    Fellowship awarded by the National Council for Science and Technology of Chile (CONICYT, www.conicyt.cl).

  •   Brigham Young University mentoring award.

    BRIGHAM YOUNG UNIVERSITY

    Estados Unidos, 2011

    Brigham Young University mentoring award.

  •   Brigham Young University graduate fellowship award.

    BRIGHAM YOUNG UNIVERSITY

    Chile, 2012

    Brigham Young University graduate fellowship award.

  •   Entrepreneurial Lead in NSF I Corps program

    Next-Gen Diagnostics

    Chile, 2013

    Entrepreneurial Lead in NSF I Corps program. Next-Gen Diagnostics.

  •   Top 100 most influential young individuals in Chile.

    DIARIO EL MERCURIO

    Chile, 2014

    Top 100 most influential young individuals in Chile. El Mercurio.

  •   MIT Technology Review innovators under 35 Chile.

    MASSACHUSETTS INSTITUTE OF TECHNOLOGY

    Estados Unidos, 2016

    MIT Technology Review innovators under 35 Chile.

  •   UC Davis Chile Fellow.

    UC Davis Chile

    Chile, 2017

    UC Davis Chile Fellow.

  •   Best Young Researcher 2017.

    UNIVERSIDAD ANDRES BELLO

    Chile, 2018

    Best Young Researcher 2017. Universidad Andrés Bello.


 

Article (55)

Biotransformation of 2,4,6-Trinitrotoluene by Pseudomonas sp. TNT3 isolated from Deception Island, Antarctica
Cartography of opportunistic pathogens and antibiotic resistance genes in a tertiary hospital environment
Copper-induced concomitant increases in photosynthesis, respiration, and C, N and S assimilation revealed by transcriptomic analyses in Ulva compressa (Chlorophyta)
Evaluation of computational methods for human microbiome analysis using simulated data
Genomic variation and arsenic tolerance emerged as niche specific adaptations by different Exiguobacterium strains isolated from the extreme Salar de Huasco environment in Chilean – Altiplano
Monitoring the occurrence of microplastic ingestion in Otariids along the Peruvian and Chilean coasts
Origin, genomic diversity and microevolution of the Clostridium difficile B1/NAP1/RT027/ST01 strain in Costa Rica, Chile, Honduras and Mexico
Sequences of Endophytic Fungal and Bacterial Communities from Araucaria araucana [(Molina) K. Koch, 1869] in the Coastal and Andes Mountain Ranges, Chile
A first insight into the structure and function of rhizosphere microbiota in Antarctic plants using shotgun metagenomic
Altered Middle Ear Microbiome in Children With Chronic Otitis Media With Effusion and Respiratory Illnesses
Analysis of co-regulated abundance of genes associated with arsenic and phosphate metabolism in Andean Microbial Ecosystems
Arsenic Response of Three Altiplanic Exiguobacterium Strains With Different Tolerance Levels Against the Metalloid Species: A Proteomics Study
Genomic and Physiological Traits o the Marine Bacterium Alcaligenes aquatilis QD168 Isolated From Quintero Bay, Central Chile, Reveal a Robust Adaptive Response to Environmental Stressors
Global Genetic Cartography of Urban Metagenomes and Anti-Microbial Resistance
In-Depth Genomic and Phenotypic Characterization of the Antarctic Psychrotolerant Strain Pseudomonas sp. MPC6 Reveals Unique Metabolic Features, Plasticity, and Biotechnological Potential
The Transcription Factor ArcA Modulates Salmonella's Metabolism in Response to Neutrophil Hypochlorous Acid-Mediated Stress
Variability in Genomic and Virulent Properties of Porphyromonas gingivalis Strains Isolated From Healthy and Severe Chronic Periodontitis Individuals
Comparative genomic analysis of a new tellurite-resistant Psychrobacter strain isolated from the Antarctic Peninsula
Complete genome sequence of the marine Rhodococcus sp H-CA8f isolated from Comau fjord in Northern Patagonia, Chile
Copper-induced increased expression of genes involved in photosynthesis, carotenoid synthesis and C assimilation in the marine alga Ulva compressa
Cyclic AMP Regulates Bacterial Persistence through Repression of the Oxidative Stress Response and SOS-Dependent DNA Repair in Uropathogenic Escherichia coli
Genome sequence of two members of the chloroaromatic-degrading MT community: Pseudomonas reinekei MT1 and Achromobacter xylosoxidans MT3
Genomic Analysis of 48 Paenibacillus larvae Bacteriophages
Metagenomic exploration of soils microbial communities associated to Antarctic vascular plants
The Tracheal Microbiota in Patients with a Tracheostomy Before, During, and After an Acute Respiratory Infection
The transcription factor SlyA from Salmonella Typhimurium regulates genes in response to hydrogen peroxide and sodium hypochlorite
Comparative Genomics Analysis of a New Exiguobacterium Strain from Salar de Huasco Reveals a Repertoire of Stress-Related Genes and Arsenic Resistance
Computational Methods for Human Microbiome Analysis
DNA Barcoding analysis of seafood accuracy in Washington, DC restaurants
Draft Genome Sequences of Five Enterococcus Species Isolated from the Gut of Patients with Suspected Clostridium difficile Infection
Genome sequence of streptomyces sp. H-KF8, a marine actinobacterium isolated from a northern chilean patagonian fjord
Microbial sequence typing in the genomic era
Mutation and recombination in pathogen evolution: Relevance, methods and controversies
The temporal dynamics of the tracheal microbiome in tracheostomised patients with and without lower respiratory infections
Draft genome sequence of a multi-metal resistant bacterium Pseudomonas putida ATH-43 isolated from Greenwich Island, Antarctica
Genome Sequence of Clostridium paraputrificum 373-A1 Isolated in Chile from a Patient Infected with Clostridium difficile
Metataxonomic and metagenomic approaches vs. culture-based techniques for clinical pathology
Redefining Healthy Urine: A Cross-Sectional Exploratory Metagenomic Study of People With and Without Bladder Dysfunction
Composition, taxonomy and functional diversity of the oropharynx microbiome in individuals with schizophrenia and controls
Concordance and discordance of sequence survey methods for molecular epidemiology
Dual Transcriptomic Profiling of Host and Microbiota during Health and Disease in Pediatric Asthma
Integrating microbial and host transcriptomics to characterize asthma-associated microbial communities
Clinical PathoScope: rapid alignment and filtration for accurate pathogen identification in clinical samples using unassembled sequencing data
PathoScope 2.0: a complete computational framework for strain identification in environmental or clinical sequencing samples
Single-Molecule Long-Read 16S Sequencing To Characterize the Lung Microbiome from Mechanically Ventilated Patients with Suspected Pneumonia
Whole genome single-nucleotide variation profile-based phylogenetic tree building methods for analysis of viral, bacterial and human genomes
Pathogen typing in the genomics era: MLST and the future of molecular epidemiology
Pathoscope: Species identification and strain attribution with unassembled sequencing data
Phage cluster relationships identified through single gene analysis
tat Exon 1 Exhibits Functional Diversity during HIV-1 Subtype C Primary Infection
Genetic diversity and molecular epidemiology of HIV transmission
Population Genomics and Phylogeography of an Australian Dairy Factory Derived Lytic Bacteriophage
The evolution of HIV: inferences using phylogenetics
Molecular Phylodynamics and Protein Modeling of Infectious Salmon Anemia Virus (ISAV)
Androgen Receptor Gene CAG and GGN Repeat Polymorphisms in Chilean Men With Primary Severe Spermatogenic Failure

BookSection (1)

Multilocus Sequence Typing of Pathogens: Methods, Analyses, and Applications

Letter (1)

In infants with severe bronchiolitis: dual-transcriptomic profiling of nasopharyngeal microbiome and host response

Proyecto (13)

Functional Potential of Rhizosphere and Soil Microbial Communities in an Extreme Environment
Salmonella-bacteriophage coevolution and their genetic modifications during lifestyle cycles of Salmonella on non-host (water and soil) and host environments (chickens)
Evaluation of Computational Methods for Human Microbiome Analysis=> A Case Study on Oral Microbiome and Childhood Asthma
Proyecto VitaTerra
REVEALING SPATIAL AND SEASONAL PATTERNS OF MICROBIAL GENETIC DIVERSITY THROUGH METAGENOMICS IN A HUMAN IMPACTED ECOSYSTEM
SBIR Phase II=> Rapid Pathogen Diagnostics and Biosurveillance using Multiplexed High-throughput Sequencing
HIV-1 evolution and compartmentalization=> spatial and temporal intra-host dynamics
Phase Ib Supplement to=> Rapid Pathogen Diagnostics and Biosurveillance using Multiplexed High- throughput Sequencing
SBIR Phase I=> Rapid Pathogen Diagnostics and Biosurveillance using Multiplexed High- throughput Sequencing
Virginia i6 VIP NextGen Diagnostics
NSF I-Corps=> NextGen Diagnostics
Technological internships=> Identification and Detection tools for Fish Alphaviruses
EVENTOS INICIALES DE LA MORFOGENESIS DE ROTAVIRUS
57
Eduardo Castro

Associate Professor

Center for Bioinformatics and Integrative Biology

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

7
Claudio Meneses

Profesor Titular

Facultad de Ciencias de la Vida

UNIVERSIDAD ANDRÉS BELLO

Santiago, Chile

4
Coral Pardo

Investigador postdoctoral

Universidad Andrés Bello

Santiago, Chile

4
Claudia Saavedra

Full Professor

Departmento de Ciencias de la Vida

UNIVERSIDAD ANDRÉS BELLO

Santiago, Chile

4
Juan Castro

Post-Doctorante

Universidad Católica del Norte

Antofagasta, Chile

3
Carolina Quezada

Postdoctoral researcher

CIBQA

Universidad Bernardo O'Higgins

Santiago, Chile

2
Daniel Laporte

Académico Investigador

Instituto de Ciencias Biomédicas

Universidad Autónoma de Chile

Talca, Chile

2
Alejandro Hidalgo

Associate Professor

Escuela de Química y Farmacia

Universidad Andres Bello

Santiago, Chile

2
Alejandra Moenne

Profesor Titular

Biologia

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

2
Juan Ugalde

Adjunct Researcher

Facultad de Ingenieria

Universidad del Desarrollo

Santiago, Chile

2
FRANCISCO REMONSELLEZ

Professor

Ingenieria Química

UNIVERSIDAD CATÓLICA DEL NORTE

Antofagasta, Chile

2
Beatriz Cámara

Associate Investigator

Departamento de Química/Centro de Biotecnología Daniel Alkalay

UNIVERSIDAD TÉCNICA FEDERICO SANTA MARÍA

Valparaíso, Chile

2
Mauricio Arenas

Profesor Asistente

Bioinformática

UNIVERSIDAD DE TALCA

talca, Chile

2
Michael Seeger

Full Professor

Chemistry

UNIVERSIDAD TÉCNICA FEDERICO SANTA MARÍA

Valparaíso, Chile

2
Ignacio Poblete

Professor

Universidad Andres Bello

santiago, Chile

2
Raul Valdevenito

Chair

UNIVERSIDAD DE CHILE, HOSPITAL CLINICO UNIVERSIDAD DE CHILE

Santiago, Chile

1
Manuel Osorio

Docente

Medicina

UNIVERSIDAD DIEGO PORTALES

Santiago, Chile

1
Roberto Durán

Asistente Científico

Química

Universidad Técnica Federico Santa María

Valparaíso, Chile

1
Pablo Muñoz

Docente

Ciencias básicas

Universidad San Sebastián

Santiago, Chile

1
Laura Rodríguez

Tesista de Doctorado

Química

Universidad Técnica Federico Santa María

Valparaiso, Chile

1
Juan García-Huidobro

Profesor Titular

Biologia

Universidad de Santiago de Chile

Santiago de Chile, Chile

1
Mauricio Urbina

Professor asistente

Zoología

Universidad de Concepcion

Concepcion, Chile

1
Gabriel Krüger

Investigador Doctoral

Universidad Andrés Bello

Santiago Centro, Chile

1
Angela Plaza

Postodoctorado

Ingeniería Civile en Obras Civil

Universidad de Santiago de Chile

Estación Central, Chile

1
Fernanda Rodríguez

Investigadora Postdoctoral

CEA

Universidad de Playa Ancha de Ciencias de la Educación

Viña del mas, Chile

1
Enzo Guerrero

PhD Student

Universidad Andrés Bello

Santiago, Chile

1
Felipe Arenas

Profesor Asociado

Biología

UNIVERSIDAD SANTIAGO DE CHILE

Santiago, Chile

1
Anilei Hoare

Profesora Asistente

Medicina y Patología Oral

Universidad de Chile

SANTIAGO, Chile

1
Paz Tapia

Ingeniera en Bioinformatica

Laboratorio Biomedico

Instituto de Salud Publica

Santiago, Chile

1
Cristóbal Galbán

Profesor Asociado

Centro de Genómica, Ecología y Medio Ambiente

Universidad Mayor de Chile

Santiago de Chile, Chile

1
Claudio Sáez

Director General

centro HUB AMBIENTAL UPLA

UNIVERSIDAD DE PLAYA ANCHA DE CIENCIAS DE LA EDUCACION

Valparaíso, Chile

1
Fernando Gonzalez

Titular Professor

Facultad de Ciencias de la Vida

Universidad Andres Bello

Santiago, Chile

1
Nicolas Pacheco

PROFESOR ADJUNTO

CIENCIAS BIOLOGICAS

Universidad Andrés Bello

Santiago centro, Chile

1
Juan Fuentes

Académico

Ciencias Biológicas

Universidad Andrés Bello

Santiago, Chile

1
Jorge Valdes

I

CENTRO DE GENOMICA Y BIOINFORMATICA

UNIVERSIDAD MAYOR

Santiago, Chile

1
Roberto Molina

Investigador Científico

Biología

Centro de Estudios Científicos

Valdivia, Chile

1
Carolina Sanchez

Assistant Professor, Faculty of Science; Principal Investigator of Advanced Genomics Laboratory; Head of DNA Sequencing Core of the Center for Genomics and Bioinformatics

Center for Genomics and Bioinformatics

Universidad Mayor

Santiago, Chile

1
Claudia Muñoz

Investigador

Biología

Universidad de Santiago de Chile

Santiago, Chile

1
Raquel Quatrini

Research Associate

Fundación Ciencia & Vida

Santiago, Chile

1
SEBASTIÁN MÁRQUEZ

Investigador

Fundación Biociencia

Santiago, Chile

1
Diego Pérez

Profesor jornada

Ecología y recursos naturales

Universidad Andrés Bello

Santiago, Chile

1
Alberto González

Académico

Biología

Universidad de Santiago de Chile

Estación Central, Chile

1
Daniel Paredes

Associate Professor

Department of Biological Sciences

Universidad Andrés Bello

Santiago, Chile

1
Andrés Marcoleta

Profesor Asistente

Biología

FACULTAD DE CIENCIAS, UNIVERSIDAD DE CHILE

Santiago, Chile

1
Alexis Parada

PROFESOR ASISTENTE

REPRODUCCION

INSTITUTO DE INVESTIGACIONES MATERNO INFANTIL, FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

1
Carolina Mascayano

Académico

Ciencias del Ambiente

UNIVERSIDAD DE SANTIAGO DE CHILE, FACULTAD DE QUÍMICA Y BIOLOGIA

santiago, Chile

1
Pablo Aguilar

PostDoc researcher

Instituto Antofagasta

Universidad de Antofagasta

Antofagasta, Chile