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Claudio Alejandro Sáez Avaria

Director General

UNIVERSIDAD DE PLAYA ANCHA DE CIENCIAS DE LA EDUCACION

Valparaíso, Chile

Ecotoxicología; biotecnología ambiental; estrés biológico; metabolómica; transcriptómica; ficología

Licenciado en Ingeniería Ambiental, UNIVERSIDAD DE VALPARAISO. Chile, 2010
PhD Marine Studies, PLYMOUTH UNIVERSITY. Reino Unido, 2014
Ingeniero Ambiental, UNIVERSIDAD DE VALPARAISO. Chile, 2010

Investigador Postdoctoral Full Time

UNIVERSIDAD DE SANTIAGO DE CHILE

Química y Biología

Santiago, Chile

2014 - 2015
Profesor Asociado Full Time

UNIVERSIDAD DE PLAYA ANCHA DE CIENCIAS DE LA EDUCACION

Ingeniería

Valparaíso, Chile

2015 - 2015
Investigador Titular Full Time

UNIVERSIDAD DE PLAYA ANCHA DE CIENCIAS DE LA EDUCACION

Viña del Mar, Chile

2016 - 2019
Director General Full Time

UNIVERSIDAD DE PLAYA ANCHA DE CIENCIAS DE LA EDUCACION

centro de investigación HUB AMBIENTAL UPLA

Valparaíso, Chile

2020 - A la fecha

Investigador Asociado Part Time

Marine Biological Association of the United Kingdom

Plymouth, Reino Unido

2013 - 2014
Profesor Asistente Part Time

Plymouth University

Plymouth, Reino Unido

2011 - 2014
Investigador Asistente Part Time

Universidad de Valparaíso

Valparaíso, Chile

2008 - 2011
Asistente de Investigación Part Time

Universidad Católica del Norte

Coquimbo, Chile

2009 - 2010
Asistente de Investigación Part Time

Victoria University of Wellington

Wellington, Nueva Zelanda

2007 - 2008
Investigador Postdoctoral Full Time

Universidad de Santiago de Chile

Santiago, Chile

2014 - 2015
Profesor Asociado Full Time

Universidad de Playa Ancha

Valparaíso, Chile

2015 - 2015
Profesor Visitante, PhD Marine Studies Part Time

Plymouth University

Plymouth, Reino Unido

2015 - A la fecha
Profesor Visitante, Doctorado en Biotecnología Part Time

Universidad de Santiago de Chile

Santiago, Chile

2015 - A la fecha
Investigador Titular Full Time

Centro de Estudios Avanzados, Universidad de Playa Ancha

Viña del Mar, Chile

2016 - 2019
Director General centro de investigación HUB AMBIENTAL UPLA Full Time

Universidad de Playa Ancha

Valparaíso, Chile

2020 - A la fecha


Antarctic intertidal macroalgae under predicted increased temperatures mediated by global climate change: Would they cope? Moenne, Alejandra; Huovinen, Pirjo; Navarro, Nelso Article WoS-ISI SCIENCE OF THE TOTAL ENVIRONMENT (2020)
Copper-induced concomitant increases in photosynthesis, respiration, and C, N and S assimilation revealed by transcriptomic analyses in Ulva compressa (Chlorophyta) SaÃ©z C.A. Article ISI SCOPUS BMC PLANT BIOLOGY (2020)
Ecophysiological and cellular stress responses in the cosmopolitan brown macroalga Ectocarpus as biomonitoring tools for assessing desalination brine impacts Valenzuela, Fernando Article WoS-ISI DESALINATION (2020)
Isolation and Characterization of Copper- and Zinc- Binding Metallothioneins from the Marine Alga Ulva compressa (Chlorophyta) Article ISI SCOPUS INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Mechanisms of Copper Tolerance, Accumulation, and Detoxification in the Marine Macroalga Ulva compressa (Chlorophyta): 20 Years of Research Moenne, Alejandra; Laporte, Daniel Article WoS-ISI PLANTS-BASEL (2020)
Physiological and metabolic responses to hypersalinity reveal interpopulation tolerance in the green macroalga Ulva compressa with different pollution histories Article WoS-ISI Aquatic Toxicology (2020)
Water-Covered Roof Versus Inverted Flat Roof on the Mediterranean Coast: A Comparative Study of Thermal and Energy Behavior Espinosa-Fernandez, Almudena; Echarri-Iribarren, Victor Article ISI APPLIED SCIENCES-BASEL (2020)
Assessment of the Requirements within the Environmental Monitoring Plans Used to Evaluate the Environmental Impacts of Desalination Plants in Chile SolÃ I.; GarcÃa-Bartolomei E.; Zarzo D. Article ISI SCOPUS WATER (2019)
Cadmium and/or copper excess induce interdependent metal accumulation, DNA methylation, induction of metal chelators and antioxidant defences in the seagrass Zostera marina Greco, Maria; Sáez, Claudio A.; Contreras, Rodrigo A.; Rodríguez-Rojas, Fernanda; Bitonti, M. Beatrice; Brown, Murray T. Article CHEMOSPHERE (2019)
Copper excess detoxification is mediated by a coordinated and complementary induction of glutathione, phytochelatins and metallothioneins in the green seaweed Ulva compressa Navarrete, Axel; González, Alberto; Gómez, Melissa; Contreras, Rodrigo A.; Díaz, Patricia; Lobos, M. Gabriela; Brown, Murray T; Sáez, Claudio A.; Moenne, Alejandra Article PLANT PHYSIOLOGY AND BIOCHEMISTRY (2019)
Distribution of Al, Cd, Cu, Fe, Mn, Pb and Zn in Liver, Gills and Muscle of Early Life Stages of Atlantic Salmon (Salmo salar) Lobos, M. Gabriela; Sáez, Claudio A.; Chavarría, Alejandra; Sepulveda, Martiza; Díaz, Patricia; Gaete, Hernán Article BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY (2019)
MAPK Pathway under Chronic Copper Excess in Green Macroalgae (Chlorophyta): Influence on Metal Exclusion/Extrusion Mechanisms and Photosynthesis Moenne F.; Brown M.T. Article ISI SCOPUS INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
MAPK Pathway under Chronic Copper Excess in Green Macroalgae (Chlorophyta): Involvement in the Regulation of Detoxification Mechanisms Moenne F.; MuÃ±oz P.T.; Lobos M.G.; SÃ¡nchez-Lizaso J.L.; Brown M.T. Article ISI SCOPUS INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Oligo-carrageenan kappa increases glucose, trehalose and TOR-P and subsequently stimulates the expression of genes involved in photosynthesis, and basal and secondary metabolisms in Eucalyptus globulus Saucedo S.; Laporte D. Article ISI SCOPUS BMC PLANT BIOLOGY (2019)
Copper stress induces antioxidant responses and accumulation of sugars and phytochelatins in Antarctic Colobanthus quitensis (Kunth) Bartl. Contreras, Rodrigo A.; Pizarro, Marisol; Kohler, Hans; Sáez, Claudio A.; Zúñiga, Gustavo E. Article BIOLOGICAL RESEARCH (2018)
Copper-induced activation of TRP channels promotes extracellular calcium entry and activation of CaMK, PKA, PKC, PKG and CBLPK leading to increased expression of antioxidant enzymes in Ectocarpus siliculosus Morales, B Article ISI SCOPUS PLANT PHYSIOLOGY AND BIOCHEMISTRY (2018)
Copper-induced activation of TRPs and VDCCs triggers a calcium signature response regulating gene expression in Ectocarpus siliculosus Moenne, A Article ISI SCOPUS PeerJ (2018)
Ecophysiological and metabolic responses to interactive exposure to nutrients and copper excess in the brown macroalga Cystoseira tamariscifolia Santillan-Sarmiento, A; Korbee, N; Figueroa, FL Article ISI SCOPUS MARINE POLLUTION BULLETIN (2018)
Phaeoviral Infections Are Present in Macrocystis, Ecklonia and Undaria (Laminariales) and Are Influenced by Wave Exposure in Ectocarpales McKeown, DA; Schroeder, JL; Stevens, K; Peters, AF; Rothman, MD; Bolton, JJ; Schroeder, DC Article ISI SCOPUS VIRUSES-BASEL (2018)
Short-term interactive effects of increased temperatures and acidification on the calcifying macroalgae Lithothamnion crispatum and Sonderophycus capensis Munoz, PT; Martinez-Callejas, MB; Bastos, E; Gurgel, CFD; Barufi, JB; Rorig, L; Horta, PA Article ISI SCOPUS AQUATIC BOTANY (2018)
Copper-induced early responses involve the activation of Transient Receptor Potential (TRP) channels, release of amino acids, serotonin and adrenalin, and activation of homologs of glutamate, adrenalin and serotonin receptors in the marine alga Ulva compressa Gomez, Melissa; Moenne, Fabiola; Sáez, Claudio A. Article ISI SCOPUS ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS (2017)
Metal assessment and cellular accumulation dynamics in the green macroalga Ulva lactuca Gabriela Lobos, M.; Sáez, Claudio A. Article SCOPUS Journal of Applied Phycology (2017)
Copper-Induced Membrane Depolarizations Involve the Induction of Mosaic TRP Channels, Which Activate VDCC Leading to Calcium Increases in Ulva compressa Gomez, Melissa; Sáez, Claudio A. Article ISI SCOPUS FRONTIERS IN PLANT SCIENCE (2016)
Copper-induced overexpression of genes encoding antioxidant system enzymes and metallothioneins involve the activation of CaMs, CDPKs and MEK1/2 in the marine alga Ulva compressa Sáez, Claudio A.; Zúñiga, Antonio; Navarrete, Axel Article ISI SCOPUS AQUATIC TOXICOLOGY (2016)
A novel field transplantation technique reveals intra-specific metal-induced oxidative responses in strains of Ectocarpus siiiculosus with different pollution histories GonzÃ¡lez A.; Contreras, RA; Moenne, A Article ISI SCOPUS Environmental Pollution (2015)
Copper-induced activation of TRP channels promotes extracellular calcium entry, activation of CaMs and CDPKs, copper entry and membrane depolarization in Ulva compressa Gómez M.; GonzÃ¡lez A.; Morales, B; Moenne, A Article ISI SCOPUS FRONTIERS IN PLANT SCIENCE (2015)
Copper-induced intra-specific oxidative damage and antioxidant responses in strains of the brown alga Ectocarpus siliculosus with different pollution histories Sáez C.A.; Roncarati F.; Moenne, A; Moody A.J.; Brown M.T. Article ISI SCOPUS AQUATIC TOXICOLOGY (2015)
Enzymatic antioxidant defences are transcriptionally regulated in Es524, a copper-tolerant strain of Ectocarpus siliculosus (Ectocarpales, Phaeophyceae) Ramesh, K; Greco M.; Bitonti, MB Article ISI SCOPUS Phycologia (2015)
Response differences between Ectocarpus siliculosus populations to copper stress involve cellular exclusion and induction of the phytochelatin biosynthetic pathway Roncarati F.; Sáez C.A.; Greco M.; Gledhill M.; Brown M.T. Article ISI SCOPUS AQUATIC TOXICOLOGY (2015)
A Simple and Effective Method for High Quality Co-Extraction of Genomic DNA and Total RNA from Low Biomass Ectocarpus siliculosus, the Model Brown Alga Greco M.; Bitonti, MB Article ISI SCOPUS PloS one (2014)
Changes in invertebrate assemblages inhabiting Lessonia spicata (Phaeophyceae) holdfasts after the 2010 earthquake-mediated coastal uplift in Chile Ortega, KJ; Macaya, EC Article ISI SCIELO REVISTA DE BIOLOGIA MARINA Y OCEANOGRAFIA (2014)
Changes in invertebrate assemblages inhabiting Lessonia spicata (Phaeophyceae) holdfasts after the 2010 earthquake-mediated coastal uplift in Chile [Cambios en los ensambles de invertebrados asociados a discos del huiro negro Lessonia spicata (Phaeophyceae) después del levantamiento costero producto del terremoto de 2010 en Chile] Sáez C.A.; Macaya, E C Article SCOPUS Revista de Biologia Marina y Oceanografia (2014)
Oligo-carrageenan kappa increases NADPH, ascorbate and glutathione syntheses and TRR/TRX activities enhancing photosynthesis, basal metabolism, and growth in Eucalyptus trees GonzÃ¡lez A.; Moenne F.; Gómez M.; Sáez C.A.; Moenne, A Article ISI SCOPUS FRONTIERS IN PLANT SCIENCE (2014)
Environmental assessment in a shallow subtidal rocky habitat: approach coupling chemical and ecological tools Sáez C.A.; Perez-Matus, A; Lobos M.G.; Oliva, D.; Vasquez J. A.; Bravo M. Article ISI SCOPUS Chemistry and Ecology (2012)
Variation in Patterns of Metal Accumulation in Thallus Parts of Lessonia trabeculata (Laminariales; Phaeophyceae): Implications for Biomonitoring Sáez C.A.; Lobos M.G.; Macaya, E C; Oliva, D.; Quiroz W.; Brown M.T. Article ISI SCOPUS PloS one (2012)


Laboratory and field based studies provide insights of copper tolerance mechanisms in brown seaweeds and biotechnology tools for environmental diagnosis Matos-Araujo, C.V.; Shinn, C. BookSection (2017)


Extension of the distributional range of Lithobius obscurus Meinert (Lithobiidae, Lithobiomorpha) in organic and conventional apple orchards in Central Chile Moya-Hernandez, MG; Vega-Roman, E; Mundaca, EA EditorialMaterial ISI Gayana (Concepciï¿½n) - International Journal of Biodiversity, Oceanology and Conservation (2015)


Centro Avanzado Para Tecnologías del Agua (CAPTA) Mcphee, James Peter Proyecto (2020)
The model brown macroalga Ectocarpus siliculosus under lead excess: evaluations at different levels of biological organization and applications for biomonitoring Montenegro Villalobos, Diana Proyecto (2020)
Biomonitoreo de salmueras para sustentabilidad ambiental de la desalación en la Región de Valparaíso Universidad de Playa Ancha (DGI Regular CEA 01-1819) Proyecto 2019-2020 Director(a)
Brown algae physiological and metabolic responses to increased salinities provide insights of tolerance mechanisms and biomonitoring tools to evaluate the impact of brine discharges from desalination plants on coastal ecosystems FONDECYT (3180394) Proyecto 2018-2021 Inv. Patrocinante
OCEANO=> PLATAFORMA DE ALTO DESEMPEÑO COMPUTACIONAL PARA LA INVESTIGACIÓN Y SOSTENIBILIDAD DE LOS ECOSISTEMAS ACUATICOS Y SUS RECURSOS FONDEQUIP (271761) Proyecto 2018-2019 Investigador(a)
Biochemical and molecular responses disclose mechanisms of Antarctic macroalgae to thrive under Climate Change INACH Regular (RT_09_16) Proyecto 2017-2020 Director(a)
Copper-induced expression of metallothioneins and synthesis of phytochelatins are involved in copper accumulation and tolerance in the marine macroalga Ulva compressa (Chlorophyta) FONDECYT (1160013) Proyecto 2016-2020 Coinvestigador(a)
Transcriptome analyses reveal the basis of signal transduction involved in copper tolerance in the marine alga Ulva compressa (Chlorophyta) using Next Generation Sequencing Technologies Sáez, Claudio A. Proyecto (2016)
Transcriptome analyses reveal the basis of signal transduction involved in copper tolerance in the marine alga Ulva compressa (Chlorophyta) using Next Generation Sequencing Technologies FONDECYT (11160369) Proyecto 2016-2019 Inv. Principal
Ecological and social effects associated with pollution by illegal dumping sites in coastal ravines of Valparaíso, Chile Universidad de Playa Ancha (Convenio Desempeño UPA 1301) Proyecto 2015-2016 Inv. Responsable
Field transplantation experiments with Ectocarpus siliculosus in central Chile Santander Universities (2012) Proyecto 2012-2013 Inv. Responsable
PhD Marine Studies, Plymouth University, Reino Unido (Becas Chile Doctorado 2010) PFCHA (72110557) Proyecto 2011-2014 Inv. Responsable
A toxico-genomic study of the model brown alga Ectocarpus siliculosus European Commision, Marie Curie Action (EC-1018579) Proyecto 2010-2012 Coinvestigador(a)
Application of seaweed biostimulants in the production of organic wine=> arsenic biotransformation and the transference of heavy metals FONDECYT (11080235) Proyecto 2008-2011 Investigador(a)
Evaluación de la biomasa de praderas naturales y prospección de potenciales lugares de repoblamiento de algas pardas en la I y II Regiones Fondo de Investigación Pesquera (2008-38) Proyecto 2008-2010 Personal técnico y/o de apoyo
Intercambio de pregrado Universidad de Valparaíso y Victoria University of Wellington (2007/2008) Proyecto 2007-2008 Inv. Responsable
Biochemical and molecular responses disclose mechanisms of Antarctic macroalgae to thrive under Climate Change Sáez, Claudio A. Proyecto (0)
Copper-induced expression of metallothioneins and synthesis of phytochelatins are involved in copper accumulation and tolerance in the marine macroalga Ulva compressa (Chlorophyta) Sáez, Claudio A. Proyecto (0)
Monitoreo ambiental del Rio Toltén, Chile, después del colapso de puente ferroviario de agosto del 2016 Sáez, Claudio A. Proyecto (0)


Mechanisms of metal tolerance in marine macroalgae, with emphasis on copper tolerance in Chlorophyta and Rhodophyta Moenne, A; GonzÃ¡lez A.; Sáez C.A. Review ISI SCOPUS AQUATIC TOXICOLOGY (2016)