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Nicolás Raúl Dutzan Muñoz

Assistant Professor

Universidad de Chile

Santiago, Chile

Líneas de Investigación


Oral mucosa immunity and inflammation with a focus in periodontal immunopathology. Th17 cells mechanisms involved in oral mucosa inflammation and periodontal disease.

Educación

  •  D.D.S, UNIVERSIDAD DE CHILE. Chile, 2003
  •  Dental Sciences, UNIVERSIDAD DE CHILE. Chile, 2008
  •  Oral and Experimental Pathology, UNIVERSITY OF MARYLAND. Estados Unidos, 2017
  •  Especialista en Periodoncia, UNIVERSIDAD DE CHILE. Chile, 2011

Experiencia Académica

  •   Assistant Professor Full Time

    UNIVERSIDAD DE CHILE

    Dentistry

    Santiago, Chile

    2007 - A la fecha

Experiencia Profesional

  •   Visiting Fellow Other

    National Institutes of Health

    Bethesda, Estados Unidos

    2013 - 2018


 

Article (23)

A dysbiotic microbiome triggers TH17 cells to mediate oral mucosal immunopathology in mice and humans
Interleukin-12 and Interleukin-23 Blockade in Leukocyte Adhesion Deficiency Type 1
On-going Mechanical Damage from Mastication Drives Homeostatic Th17 Cell Responses at the Oral Barrier
Characterization of the human immune cell network at the gingival barrier
Isolation, Characterization and Functional Examination of the Gingival Immune Cell Network
Changes in lipopolysaccharide profile of Porphyromonas gingivalis clinical isolates correlate with changes in colony morphology and polymyxin B resistance
Host response mechanisms in periodontal diseases
Subgingival Microbial Communities in Leukocyte Adhesion Deficiency and Their Relationship with Local Immunopathology
Defective Neutrophil Recruitment in Leukocyte Adhesion Deficiency Type I Disease Causes Local IL-17-Driven Inflammatory Bone Loss
Interferon-gamma, Interleukins-6 and -4, and Factor XIII-A as Indirect Markers of the Classical and Alternative Macrophage Activation Pathways in Chronic Periodontitis
Melanoma cell lysate induces CCR7 expression and in vivo migration to draining lymph nodes of therapeutic human dendritic cells
The subgingival microbiome in health and periodontitis and its relationship with community biomass and inflammation
Interleukin-21 Expression and Its Association With Proinflammatory Cytokines in Untreated Chronic Periodontitis Patients
Levels of Interleukin-21 in Patients With Untreated Chronic Periodontitis
Associations Between Matrix Metalloproteinase-8 and -14 and Myeloperoxidase in Gingival Crevicular Fluid From Subjects With Progressive Chronic Periodontitis: A Longitudinal Study
Chemokine Monocyte Chemoattractant Protein-3 in Progressive Periodontal Lesions in Patients With Chronic Periodontitis
Monocyte chemotactic protein-3: possible involvement in apical periodontitis chemotaxis
Levels of Interferon-Gamma and Transcription Factor T-Bet in Progressive Periodontal Lesions in Patients With Chronic Periodontitis
Over-expression of forkhead box P3 and its association with receptor activator of nuclear factor-kappa B ligand, interleukin (IL)-17, IL-10 and transforming growth factor-beta during the progression of chronic periodontitis
Proteolytic roles of matrix metalloproteinase (MMP)-13 during progression of chronic periodontitis: initial evidence for MMP-13/MMP-9 activation cascade
Characterization of progressive periodontal lesions in chronic periodontitis patients: levels of chemokines, cytokines, matrix metalloproteinase-13, periodontal pathogens and inflammatory cells
RANKL in human periapical granuloma: possible involvement in periapical bone destruction
Levels of interleukin-17 in gingival crevicular fluid and in supernatants of cellular cultures of gingival tissue from patients with chronic periodontitis

Review (1)

Host-Pathogen Interactions in Progressive Chronic Periodontitis
24
Nicolás Dutzan

Assistant Professor

Facultad de Odontología, Departamento de Odontología Conservadora

Universidad de Chile

Santiago, Chile

17
Rolando Vernal

Profesor Titular

Departamento de Odontología Conservadora

UNIVERSIDAD DE CHILE

Santiago, Chile

16
Jorge Gamonal

Académico

Odontología Conservadora

FACULTAD DE ODONTOLOGÍA, UNIVERSIDAD DE CHILE

Santiago, Chile

14
Jorge Gamonal

PROFESOR TITULAR

ODONTOLOGIA CONSERVADORA

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

11
Emma Hernandez

Académico 44 h, profesor titular

Oral Patology and Medicine

Universidad de Chile, Facultad de Odontología

SANTIAGO, Chile

9
Loreto Abusleme

Assistant Professor

Oral pathology and medicine

FACULTAD DE ODONTOLOGÍA, UNIVERSIDAD DE CHILE

Santiago, Chile

4
Patricia Pozo

Académico

Ciencias Farmacéuticas

UNIVERSIDAD CATÓLICA DEL NORTE

Antofagasta, Chile

3
Timo Sorsa

Visiting Professor of Oral Biology

Institute of Dentistry

Karolinska Institutet

Stockholm, Suecia

3
Juan Aguillón

PROFESSOR

IMMUNOLOGY PROGRAM

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

2
Alejandra Chaparro

Profesora Titular

Odontología

UNIVERSIDAD DE LOS ANDES

Santiago, Chile

2
Maria Valenzuela

Profesor TItular

Bioquimica y Biología Molecular

Universidad de Chile

Santiagao, Chile

2
Fermín González

Profesor Asociado

universidad de chile

Santiago, Chile

2
Taina Tervahartiala

Research Scientist

Biomedicum-Institute of Dentistry

Universidad de Helsinki

Helsinki, Finlandia

1
Mercedes López

Profesora Asociada

Instituto de Ciencias Biomédicas

Universidad de chile

Santiago, Chile

1
María Gleisner

INVESTIGADOR POSTDOCTORAL

ICBM

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

1
José Pérez

Associate Professor

Biologia

Universidad Andres Bello

Santiago, Chile

1
Paola Carvajal

Profesora Asistente

Odontologia Conservadora

FACULTAD DE ODONTOLOGÍA UNIVERSIDAD DE CHILE

Santiago, Chile

1
OCTAVIO ARAVENA

INVESTIGADOR

INSTITUTO CIENCIAS BIOMÉDICAS

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Jeannette Mardones

Profesora Adjunta

Odontología Conservadora

Universidad de Chile

Santiago, Chile

1
Marcela Alcota

Profesora Asistente

Odontologia Conservadora

Universidad de Chile

Santiago, Chile

1
sabrita chandia

academico

Departamento de Educacion en Ciencias de la Salud

Universidad de Chile

Santiago , Chile