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Carmen Aurora Romero Osses

Jefe Laboratorio Endocrinología y Biología Reproductiva

HOSPITAL CLÍNICO UNIVERSIDAD DE CHILE

Santiago, Chile

- Neuroendocrinología del ovario de mamíferos.- Importancia de las neurotrofinas en especial del factor de crecimiento nervioso (NGF) en la función ovárica normal y en cancer ovárico. Evaluación de oncoproteínas y microRNAs en Cáncer de Ovario.

Bioquimica, UNIVERSIDAD DE CHILE. Chile, 1973
Biología de la Reproducción, UNIVERSIDAD DE CHILE. Chile, 1983
Neuro-Endocrinología del Ovario, OREGON HEALTH SCIENCES UNIVERSITY. Estados Unidos, 1999
Gestión en Salud, UNIVERSIDAD DE CHILE. Chile, 2000

Profesor Titular Part Time

UNIVERSIDAD DE CHILE

Ciencias Químicas y Farmacéuticas

Santiago, Chile

2010 - A la fecha
Docente en diferentes cursos de pre y post grado Full Time

UNIVERSIDAD DE CHILE

Medicina

Santiago, Chile

1973 - A la fecha

Jefe Laboratorio de Endocrinología y Biología Reproductiva Hospital Clínico Universidad de Chile Full Time

Universidad de Chile

Santiago, Chile

1973 - A la fecha
Académico de Facultad de Ciencias Químicas y Farmacéuticas Part Time

Universidad de Chile

Santiago, Chile

2009 - A la fecha
WHO Fellow Full Time

London University

Londres, Reino Unido

1977 - 1978
WHO Fellow Full Time

Hospital Libre de Bruselas

Bruselas, Bélgica

1978 - 1978

Durante mi carrera profesional y académica he dirigido variadas Tesis tanto de pregrado como de postgrado:

ALUMNOS DE LA FACULTAD DE CIENCIAS QUÍMICAS Y FARMACÉUTICAS, UNIVERSIDAD DE CHIE:

- Tesis Optar el Título de Bioquímico
- Tesis de Magister en Bioquímica
- Tesis de Doctorado en Bioquímica
- Tesis de Doctorado en Ciencias Farmacológicas,
- Tesis de Doctorado en Farmacología

ALUMNOS DE LA FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

- Tesis para optar al Título de Tecnólogo Médico,
- Tesis de Magister en Ciencias Biomédicas

HE REALIZADO DIFUSIÓN DE MI TRABAJO DE INVESTIGACIÓN A ALUMNOS DE LA COMUNA DE INDEPENDENCIA

SE HA REALIZADO DIFUSIÓN DE MI TRABAJO DE INVESTIGACIÓN EN VARIOS SIMPOSIOS NACIONALES E INTERNACIONALES ASI COMO TAMBIEN EN CONGRESOS NACIONALES E INTERNACIONALES


Follicle-stimulating hormone promotes nerve growth factor and vascular endothelial growth factor expression in epithelial ovarian cells. Garrido MP, Bruneau N, Vega M, Selman A, Tapia JC, Romero C. Article ISI IF: 1.77 Epub ahead of print HISTOLOGY AND HISTOPATHOLOGY (2020)
NGF/TRKA Decrease miR-145-5p Levels in Epithelial Ovarian Cancer Cells. Garrido MP, Torres I, Avila A, Chnaiderman J, Valenzuela-Valderrama M, Aramburo J, Oróstica L, Durán-Jara E, Lobos-Gonzalez L, Romero C. Article ISI Impact Factor::4.556 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Angiogenesis in Gynecological Cancers: Role of Neurotrophins Garrido MP., Torres I., Vega M., Romero C Article ISI IF: 4.137 FRONTIERS IN ONCOLOGY (2019)
NGF-Enhanced Vasculogenic Properties of Epithelial Ovarian Cancer Cells Is Reduced by Inhibition of the COX-2/PGE2 Signaling Axis. Garrido MP, Hurtado I, Valenzuela-Valderrama M, Salvatierra R, Hernández A, Vega M, Selman A, Quest AFG, Romero C*. Article ISI IF: 6.102 Cancers (2019)
Effect of TNF-alpha on Molecules Related to the Insulin Action in Endometrial Cells Exposed to Hyperandrogenic and Hyperinsulinic Conditions Characteristics of Polycystic Ovary Syndrome Orostica, L; Garcia, P; Vera, C; garcia, v; Romero, C; Vega, M Article ISI SCOPUS REPRODUCTIVE SCIENCES (2018)
Effect of TNF-α on molecules related to the insulin action in endometrial cells exposed to hyperandrogenic and hyoerinsulinic conditions characteristics of Polycystic Ovary Syndrome (PCOS). Oróstica L; García P,; Vera, C.; García V,; Romero, C.; Vega M. Article ISI IF: 2.559 Reproduction Science (2018)
Metformin prevents nerve growth factor-dependent proliferative and proangiogenic effects in epithelial ovarian cancer cells and endothelial cells Garrido MP, Vera C; Vega M, Quest AF; , Romero C Article Ther Adv Med Oncol. (2018)
Metformin prevents nerve growth factor-dependent proliferative and proangiogenic effects in epithelial ovarian cancer cells and endothelial cells. 1. Garrido, M; Vera, C.; Vega, M; Quest, A; Romero, C Article ISI IF: 5.67 THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY (2018)
Metformin prevents nerve growth factor-dependent proliferative and proangiogenic effects in epithelial ovarian cancer cells and endothelial cells. Garrido MP, Vera C; Vega M, Quest AFG Article THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY (2018)
Combined dexamethasone and desmopressin test in the differential diagnosis of ACTH-dependent Cushing's syndrome and pseudo-cushing's states. Araya, AV; Romero, C; Lemp, M Article PITUITARY (2017)
Effect of estradiol on the expression of angiogenic factors in epithelial ovarian cancer Valladares Macarena, Plaza-Parrochia Francisca; Lépez Macarena , López Daniela; Gabler Fernando, Gayan ; Selman Alberto, Vega Margarita Article Histology and Histopathology (2017)
Effect of estradiol on the expression of angiogenic factors in epithelial ovarian cancer Valladares, M.; Plaza-Parrochia F, ,; Lépez M; López D; Gabler F.; Gayan P.,; Selman A.; Vega M.; Romero, C Article ISI IF: 1.777 HISTOLOGY AND HISTOPATHOLOGY (2017)
Endometrium and steroids, a pathologic overview Plaza-Parrochia, F ; Romero, C ; Valladares, L ; Vega, M Article STEROIDS (2017)
Maternal Plasma Nerve Growth Factor at the 11(+0)-13(+6) Weeks' Scan as a Potential Angiogenic Marker of Preeclampsia: A Pilot Study Sepúlveda-Martínez A.; Garrido M.; Caamano E.; Vega M.; Romero C.; Parra-Cordero M. Article ISI SCOPUS FETAL DIAGNOSIS AND THERAPY (2017)
Molecular Mechanisms of Androstenediol in the Regulation of the Proliferative Process of Human Endometrial Cells Plaza-Parrochia F.; Oróstica L.; García P.; Vera C.; Romero C.; Valladares L.; Vega M. Article ISI SCOPUS REPRODUCTIVE SCIENCES (2017)
Molecular mechanisms of androstenediol in the regulation of the proliferative process of human endometrial cells. Plaza-Parrochia F, ,; Orostica L; García P; Vera, C.; Romero, C.; Valladares, L.; Vega M. Article Reproductive Sciences (2017)
Role of Nerve Growth Factor (NGF) and miRNAs in epithelial ovarian cancer. Rocío Retamales-Ortega; Lorena Oróstica; Carolina Vera,; Paula Cuevas; Andrea Hernández,; Iván Hurtado; Margarita Vega; Carmen Romero. Article ISI IF: 4.183 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
The nerve growth factor alters calreticulin translocation from the endoplasmic reticulum to the cell surface and its signaling pathway in epithelial ovarian cancer cells Vera Carolina, Oróstica Lorena; Gabler Fernando, Ferreira Arturo; Selman Alberto, Vega Margarita Article INTERNATIONAL JOURNAL OF ONCOLOGY (2017)
The Nerve Growth Factor calreticulin translocation from the endoplasmic reticulum to the cell surface and its signaling pathway in epithelial ovarian cancer. Carolina Vera,; Lorena Oróstica,; Fernando Gabler; Arturo Ferreira; Alberto Selman; Margarita Vega; Carmen Romero. Article ISI IF: 3.571 INTERNATIONAL JOURNAL OF ONCOLOGY (2017)
Altered steroid metabolism and insulin signaling in PCOS endometria: Impact in tissue function Oróstica L; Rosas C; Plaza-Parrochia F; Astorga I; Gabler F; García V; Romero C Article Current Pharmaceutical Design (2016)
https://pubmed.ncbi.nlm.nih.gov/26614265/ Carlos Rosas, Lorena Oróstica, Cristian Poblete, Rodrigo Carvajal, Fernando Gabler, Carmen Romero, Sergio Lavandero, Margarita Vega Article ISI IF: 2.559 REPRODUCTIVE SCIENCES (2016)
Levels of Regulatory Proteins Associated With Cell Proliferation in Endometria From Untreated Patients Having Polycystic Ovarian Syndrome With and Without Endometrial Hyperplasia Bacallao, K; Plaza-Parrochia, F; Cerda A.; Gabler F.; Romero C.; Vantman D; Vega M. Article ISI SCOPUS REPRODUCTIVE SCIENCES (2016)
Role of dihydrotestosterone (DHT) on TGF-beta 1 signaling pathway in epithelial ovarian cancer cells Kohan-Ivani, K; Gabler F.; Selman A.; Vega M.; Romero C. Article ISI SCOPUS JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2016)
Role of dihydrotestosterone (DHT) on TGF-β1 signaling pathway in epithelial ovarian cancer cells. Kohan-Ivani K, Gabler F, Selman A, Vega M, Romero C Article ISI IF: 3,332 JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2016)
Causes and management of severe acute liver damage during pregnancy [Actualización en el diagnóstico y manejo del daño hepático agudo grave en el embarazo] Sepulveda-Martinez, A; Romero C.; Juarez, G; Hasbun, J; Parra-Cordero, M Article SCOPUS Revista Medica de Chile (2015)
Endometria from Obese PCOS Women with Hyperinsulinemia Exhibit Altered Adiponectin Signaling garcia, v; Oróstica L.; Poblete C.; Rosas, C; Astorga, I.; Romero C.; Vega M. Article ISI SCOPUS Hormone and Metabolic Research (2015)
Endometria from Obese PCOS women with hyperinsulinemia exhibit altered adiponectin signaling García V; Oróstica L; Poblete C; Rosas C; Astorga I; Romero C Article Hormone and Metabolic Research (2015)
Enhanced caveolin-1 expression increases migration, anchorage-independent growth and invasion of endometrial adenocarcinoma cells Diaz-Valdivia, N; Bravo D.; Huerta, H.; Henríquez S.; Gabler F.; Vega M.; Romero C.; Calderón C; Owen, GI; Leyton, L; Quest, AFG Article ISI SCOPUS BMC Cancer (2015)
Expression of steroid sulfated transporters and 3 beta-HSD activity in endometrium of women having polycystic ovary syndrome Plaza-Parrochia, F; Poblete C.; Gabler F.; Carvajal R.; Romero C.; Valladares, L; Vega M. Article ISI SCOPUS Steroids (2015)
Expression of steroid sulfated transporters and 3β-HSD activity in endometrium of women having polycystic ovary syndrome Plaza-Parrochia F; Poblete C; Gabler F; Carvajal R; Romero C; Valladares L Article Steroids (2015)
Hyperandrogenism Decreases GRP78 Protein Level and Glucose Uptake in Human Endometrial Stromal Cells Rosas, C; Oróstica L.; Poblete C.; Carvajal R.; Gabler F.; Romero C.; Lavandero S.; Vega M. Article SCOPUS Reproductive Sciences (2015)
Plasma ghrelin levels in the late postoperative period of vertical sleeve gastrectomy Braghetto, I; Taladriz C.; Lanzarini, E; Romero C. Article ISI REVISTA MEDICA DE CHILE (2015)
Plasma ghrelin levels in the late postoperative period of vertical sleeve gastrectomy [Efecto de la gastrectomía tubular vertical en los niveles de ghrelina plasmática en pacientes obesos] Braghetto, I; Taladriz C.; Lanzarini, E; Romero C. Article SCOPUS Revista Medica de Chile (2015)
Association between obesity and ovarian cancer Valladares, M; Corsini, G; Romero C. Article ISI REVISTA MEDICA DE CHILE (2014)
Association of genetic variants at TOX3, 2q35 and 8q24 with the risk of familial and early-onset breast cancer in a South-American population Elematore, I; Gonzalez-Hormazabal, P; Reyes, JM.; Blanco, R; Bravo T.; Peralta O.; Gomez, F; Waugh E.; Margarit, S; Ibanez, G; Romero C.; Pakomio, J; Roizen, G; Di Capua GA; Jara, L Article ISI SCOPUS MOLECULAR BIOLOGY REPORTS (2014)
Role of Nerve Growth Factor and its TRKA receptor in normal ovarian and epithelial ovarian cancer angiogenesis Carolina Vera, Verónica Tapia, Margarita Vega and Carmen Romero Article Journal of Ovarian Research (2014)
The role of androst-5-ene-3 beta,17 beta-diol (androstenediol) in cell proliferation in endometrium of women with polycystic ovary syndrome Plaza-Parrochia, F; Bacallao, K; Poblete C.; Gabler F.; Carvajal R.; Romero C.; Valladares, L; Vega M. Article ISI SCOPUS STEROIDS (2014)
Decreased Phosphorylation of Y(14)Caveolin-1 in Endometrial Tissue of Polycystic Ovary Syndrome Patients may be Related with an Insulin Resistant State in this Tissue Ormazabal P.; Romero C.; Gabler F.; Quest, AFG; Vega M. Article ISI SCOPUS Hormone and Metabolic Research (2013)
Genetic variants in FGFR2 and MAP3K1 are associated with the risk of familial and early-onset breast cancer in a South-American population Jara, L; Gonzalez-Hormazabal, P; Cerceno, K; Di Capua GA; Reyes, JM.; Blanco, R; Bravo T.; Peralta O.; Gomez, F; Waugh E.; Margarit, S; Ibanez, G; Romero C.; Pakomio, J; Roizen, G Article ISI SCOPUS Breast Cancer Research and Treatment (2013)
Metformin augments the levels of molecules that regulate the expression of the insulin-dependent glucose transporter GLUT4 in the endometria of hyperinsulinemic PCOS patients Carvajal R.; Rosas, C; Kohan, K; Gabler F.; Vantman D; Romero C.; Vega M. Article ISI SCOPUS Human Reproduction (2013)
Testosterone Modulates the Expression of Molecules Linked to Insulin Action and Glucose Uptake in Endometrial Cells Ormazabal P.; Romero C.; Quest, AFG; Vega M. Article ISI SCOPUS Hormone and Metabolic Research (2013)
ADAM17 and TRKA receptor are involved in epithelial ovarian cancer progression, Girardi, S (Girardi, Silvana) ; Tapia, V (Tapia, Veronica); Kohan, K (Kohan, Karla) ; Contreras, H (Contreras, Hector) ; Gabler, F (Gabler, Fernando) ; Selman, A (Selman, Alberto); Vega, M (Vega, Margarita) ; Romero, C (Romero, Carmen). Article International Journal of Molecular Medicine (2012)
Advances in Neuroendocrine Mechanisms, S. K. Mani, H. Lara, C. Romero, R. J. Handa, T. J. Wu. Article Hormone and Metabolic Research (2012)
Advances in Neuroendocrine Mechanisms, S. K. Mani, H. Lara, C. Romero, R. J. Handa, T. J. Wu. Article Hormone and Metabolic Research (2012)
Nerve Growth Factor Induces the Expression of Chaperone Protein Calreticulin in Human Epithelial Ovarian Cells Vera C.; Tapia, V; Kohan, K; Gabler F.; Ferreira A.; Selman A.; Vega M.; Romero C. Article ISI SCOPUS Hormone and Metabolic Research (2012)
Nerve growth factor induces the expression of chaperone protein calreticulin in human epithelial ovarian cells. Vera C, Tapia V, Kohan K, Gabler F, Ferreira A, Selman A, Vega M, Romero C. Article Horm Metab Res. (2012)
Nerve Growth Factor Stimulates Cellular Proliferation of Human Epithelial Ovarian Cancer Urzua, U; Tapia, V; Geraldo M.P.; Selman A.; Vega M.; Romero C. Article ISI SCOPUS Hormone and Metabolic Research (2012)
Protein expression of PKCZ (Protein Kinase C Zeta), Munc18c, and Syntaxin-4 in the insulin pathway in endometria of patients with polycystic ovary syndrome (PCOS) Rivero, R; Garin C.-A.; Ormazabal P.; Silva, A; Carvajal R.; Gabler F.; Romero C.; Vega M. Article ISI SCOPUS Reproductive Biology and Endocrinology (2012)
Role of dihydrotestosterone (DHT) on the TGF-beta 1 receptors expression in epithelial ovarian cancer, Kohan, K (Kohan, K.) ; Tapia, V (Tapia, V.); Vega, M (Vega, M.); Romero, C (Romero, C.). Article Tumor Biology (2012)
The Chaperone Protein Calreticulin Is Expressed in Human Ovarian Tissues Romero, C (Romero, Carmen); Vera, C (Vera, Carolina); Gabler, F (Gabler, Fernando); Ferreira, A (Ferreira, Arturo) ; Selman, A (Selman, Alberto) ; Vega, M (Vega, Margarita). Article Biology of Reproduction (2011)
Tyrosine kinase A receptor (trkA): A potential marker in epithelial ovarian cancer Tapia, V; Gabler F.; Munoz M.; Yazigi R.; Paredes A.; Selman A.; Vega M.; Romero C. Article ISI SCOPUS Gynecologic Oncology (2011)
Changes in the Expression of Insulin Signaling Pathway Molecules in Endometria from Polycystic Ovary Syndrome Women with or without Hyperinsulinemia Fornes, R; Ormazabal P.; Rosas, C; Gabler F.; Vantman D; Romero C.; Vega M. Article ISI SCOPUS Molecular Medicine (2010)
Changes in the Expression of Insulin Signaling Pathway Molecules in Endometria from Polycystic Ovary Syndrome Women with or without Hyperinsulinemia. Molecular medicine, Romina Fornes, Paulina Ormazabal, Carlos Rosas, Fernando Gabler, David Vantman, Carmen Romero,and Margarita Vega. Article Molecular Medicine, (2010)
Determinación de los niveles de cortisol salival en una muestra de sujetos de Santiago de Chile LÉPEZ, MACARENA; CAAMAÑO, EGARDO; Romero, Carmen; Fiedler, Jenny; Araya, Verónica Article SCIELO REVISTA MEDICA DE CHILE (2010)
Isolation of Viable Porcine Islets by Selective Osmotic Shock Without Enzymatic Digestion Atwater I; Guajardo, M; Caviedes P.; Jeffs, S; Parrau, D; Valencia, M; Romero C.; Arriagada C.; Caamaño E.; Salas, A.; Olguin, F.; Atlagich, M.; Maas, R; Mears, D; Rojas, E Article ISI SCOPUS Transplantation Proceedings (2010)
Levels of Rabs and WAVE family proteins associated with translocation of GLUT4 to the cell surface in endometria from hyperinsulinemic PCOS women Rosas, C; Gabler F.; Vantman D; Romero C.; Vega M. Article ISI SCOPUS Human Reproduction (2010)
Role of the transcriptional factors FOXO1 and PPARG on gene expression of SLC2A4 in endometrial tissue from women with polycystic ovary syndrome Kohan, K; Carvajal R.; Gabler F.; Vantman D; Romero C.; Vega M. Article ISI SCOPUS Reproduction (2010)
Salivary cortisol among subjects with and without Cushing syndrome Lepez, M; Caamaño E.; Romero C.; Fiedler J.; Araya, V Article ISI REVISTA MEDICA DE CHILE (2010)
Salivary cortisol among subjects with and without Cushing Syndrome [Determinación de los niveles de cortisol salival en una muestra de sujetos de Santiago de Chile] LÃ©pez M.; CaamaÃ±o E.; Romero C.; Fiedler J.; Araya, V Article SCOPUS Revista Medica de Chile (2010)
The conversion of dehydroepiandrosterone into androst-5-ene-3 beta,17 beta-diol (androstenediol) is increased in endometria from untreated women with polycystic ovarian syndrome Plaza, F; Gabler F.; Romero C.; Vantman D; Valladares, L; Vega M. Article ISI SCOPUS Steroids (2010)
Increased free fetal DNA levels in early pregnancy plasma of women who subsequently develop preeclampsia and intrauterine growth restriction Illanes, S; Parra,M; Serra R.; Pino, K; Figueroa-Diesel, H; Romero C.; Arraztoa JA; Michea, L.; Soothill, PW Article ISI SCOPUS PRENATAL DIAGNOSIS (2009)
Nerve Growth Factor Induces Vascular Endothelial Growth Factor Expression in Granulosa Cells via a trkA Receptor/Mitogen-Activated Protein Kinase-Extracellularly Regulated Kinase 2-Dependent Pathway Julio-Pieper, M; Lozada, P; Tapia, V; Vega M.; Miranda, C.; Vantman D; Ojeda, SR; Romero C. Article ISI SCOPUS JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2009)
Activities of steroid metabolic enzymes in secretory endometria from untreated women with Polycystic Ovary Syndrome Leon, L.; Bacallao, K; Gabler F.; Romero C.; Valladares, L; Vega M. Article ISI SCOPUS STEROIDS (2008)
In situ estrogen metabolism in proliferative endometria from untreated women with polycystic ovarian syndrome with and without endometrial hyperplasia Bacallao, K; Leon, L.; Gabler F.; Soto, E; Romero C.; Valladares, L; Vega M. Article ISI SCOPUS JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2008)
Nerve growth factor and its high-affinity receptor trkA participate in the control of vascular endothelial growth factor expression in epithelial ovarian cancer Campos X; Muñoz Y.; Selman A.; Yazigi R.; Moyano L.; Weinstein-Oppenheimer C.; Lara, HE; Romero C. Article ISI SCOPUS GYNECOLOGIC ONCOLOGY (2007)
Effects of nerve growth factor (NGF) on blood vessels area and expression of the angiogenic factors VEGF and TGFbetaI in the rat ovary Julio-Pieper, M; Lara, HE; Bravo, JA; Romero C. Article ISI SCOPUS REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY (2006)
Expression of molecules associated with tissue homeostasis in secretory endometria from untreated women with polycystic ovary syndrome Avellaira, C; Villavicencio A.; Bacallao, K; Gabler F.; Wells, P; Romero C.; Vega M. Article ISI SCOPUS HUMAN REPRODUCTION (2006)
Nerve growth factor-dependent activation of trkA receptors in the human ovary results in synthesis of follicle-stimulating hormone receptors and estrogen secretion Salas C.; Julio-Pieper, M; Valladares, M; Pommer R.; Vega M.; Mastronardi, C; Kerr, B.; Ojeda, SR; Lara, HE; Romero C. Article ISI SCOPUS JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2006)
TrkB receptors are required for follicular growth and oocyte survival in the mammalian ovary Paredes A.; Romero C.; Dissen G.A.; Cornea A.; Ojeda S.R.; DeChiara T.M.; Reichardt L.; Xu, B. Article SCOPUS DEVELOPMENTAL BIOLOGY (2004)
Evaluation of tumor necrosis factor alpha production in ex vivo short term cultured whole blood from women with polycystic ovary syndrome Araya, AV; Aguirre A.; Romero C.; Miranda, C.; Molina, MC; Ferreira A. Article ISI SCOPUS European Cytokine Network (2002)
Nerve growth factor induces the expression of functional FSH receptors in newly formed follicles of the rat ovary Paredes A.; Dissen G.A.; Ojeda S.R.; Romero C. Article SCOPUS ENDOCRINOLOGY (2002)
Neurotrophic control of ovarian development Dissen, GA; Romero C.; Paredes A.; Ojeda, SR Article ISI MICROSCOPY RESEARCH AND TECHNIQUE (2002)
Nerve growth factor is required for early follicular development in the mammalian ovary Dissen G.A.; Romero C.; Ojeda S.R.; Hirshfield A.N. Article SCOPUS ENDOCRINOLOGY (2001)
Release of norepinephrine from human ovary - Coupling to steroidogenic response Lara, HE; Porcile A.; Espinoza J.; Romero C.; Luza, SM,; Fuhrer J.; Miranda, C.; Roblero, L Article ISI SCOPUS ENDOCRINE (2001)
Metformin Reduces NGF-Induced Tumour Promoter Effects in Epithelial Ovarian Cancer Cells . Garrido M, Salvatierra R, Valenzuela Valderrama M, Vallejos C. Bruneau N, Hernandez A, Vega M, Selman A, Quest A, Romero C. Article PHARMACEUTICALS
Pro-Inflammatory Markers Negatively Regulate IRS1 in Endometrial Cells and Endometrium from Women with Obesity and PCOS • Orostica, L; Poblete, C; Romero, C, et al Article REPRODUCTIVE SCIENCES
The insulin-sensitizing mechanism of myo-inositol is associated with AMPK activation and GLUT-4 expression in human endometrial cells exposed to a PCOS environment Heidy Cabrera-Cruz; Lorena Oróstica, Francisca Plaza-Parrochia, Ignacio Torres-Pinto, Carmen Romero, Margarita Vega Article AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
The nerve growth factor alters calreticulin translocation from the endoplasmic reticulum to the cell surface and its signaling pathway in epithelial ovarian cancer Vera CA, Oróstica L, Gabler F, Ferreira A, Selman A, Vega M, Romero CA. Article ISI FI: 3.571 INTERNATIONAL JOURNAL OF ONCOLOGY


Activation of TRKA receptor by nerve growth factor induces shedding of P75 receptor related with progression of epithelial ovarian cancer Romero C.; Vallejos C.; Gabler F.; Selman A.; Vega M. Abstract ISI EUROPEAN JOURNAL OF CANCER (2014)
Is DHT involved in the action of TGF-beta 1 in epithelial ovarian cancer? Kohan, K; Poblete C.; Vega M.; Romero C. Abstract ISI CANCER RESEARCH (2013)
ADAM17 and TRKA receptor are involved in epithelial ovarian cancer progression Girardi, S; Tapia, V; Kohan, K; Contreras H.; Gabler F.; Selman A.; Vega M.; Romero C. Abstract ISI INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2012)
Role of dihydrotestosterone (DHT) on the TGF-beta 1 receptors expression in epithelial ovarian cancer Kohan, K; Tapia, V; Vega M.; Romero C. Abstract ISI TUMOR BIOLOGY (2012)
ADAM17 Expression Is Increased in Epithelial Ovarian Carcinoma. Tapia, VM; Amtmann, N; Gabler F.; Selman A.; Vega M.; Romero C. Abstract ISI BIOLOGY OF REPRODUCTION (2011)
The Chaperone Protein Calreticulin Is Expressed in Human Ovarian Tissues Romero C.; Vera C.; Gabler F.; Ferreira A.; Selman A.; Vega M. Abstract ISI BIOLOGY OF REPRODUCTION (2011)
NGF increases the expression of VEGF in epithelial ovarian carcinoma. Campos X; Oddo D.; Selman A.; Martinez L.; Moyano L.; Yazigi R.; Lara, H; Romero C. Abstract ISI BIOLOGY OF REPRODUCTION (2005)


Advances in Neuroendocrine Mechanisms Mani S.K.; Lara, H; Romero C.; Handa R.J.; Wu T.J. EditorialMaterial ISI SCOPUS Hormone and Metabolic Research (2012)


ROLE OF NERVE GROWTH FACTOR ON THE REGULATION OF MIRNAS 23B AND MIRNA145 AND INFLAMMATORY MOLECULES INVOLVED IN CELL PROLIFERATION AND TUMOR ANGIOGENESIS OF EPITHELIAL OVARIAN CANCER FONDECYT (1160139) Proyecto 2016-2020 Inv. Responsable
Centro de estudios avanzados de enfermedades crónicas (ACCDiS) FONDAP (15130011) Proyecto 2014-2019 Investigador(a)
Involvement of adiponectin in the regulation of endometrial metabolic function of obese women bearing polycystic ovarian syndrome and hiperinsulinism FONDEF (1130053) Proyecto 2013-2017 Coinvestigador(a)
Ovarian cancer initiation and spread in a syngeneic mouse model at estropausal state FONDEF (1130292) Proyecto 2013-2016 Coinvestigador(a)
Desarrollo de una plataforma tecnológica para análisis cuantitativos, cualitativo y de distribución subcelular de proteínas FONDEQUIP (EQM-120114) Proyecto 2012-2013 Investigador(a)
"CONTRIBUTION OF TRKA RECEPTOR ISOFORMS TO THE CELLULAR PROLIFERATION AND ANGIOGENESIS OF EPITHELIAL OVARIAN CANCER=> POTENTIAL TARGETS FOR THERAPEUTIC INTERVENTION" FONDECYT (1110372) Proyecto 2011-2015 Inv. Responsable
Contribution of trkA receptor isoforms to the cellular proliferation and angiogenesis of epithelial ovarian cancer=> Potential targets for therapeutic intervention. FONDEF (1110372) Proyecto 2011-2015 Inv. Responsable
EFECTO DE LA CONDICION HIPERANDROGENICA E HIPERINSULINICA SOBRE MOLECULAS REGULADORAS DE LA EXPRESION Y TRAFICO INTRACELULAR DEL TRANSPORTADOR DE GLUCOSA GLUT4 EN ENDOMETRIOS DE PACIENTES CON SINDROME DE OVARI POLIQUISTICO FONDECYT (1095127) Proyecto 2009-2013 Coinvestigador(a)
PARTICIPACION DEL RECEPTOR trkA Y SU LIGANDO, EL FACTOR DE CRECIMIENTO NERVIOSO (NGF), EN LA GENESIS Y PROGRESION DEL CANCER OVARICO EPITELIAL. FONDECYT (1071036) Proyecto 2007-2011 Inv. Responsable
"PARTICIPACION DEL MICROAMBIENTE ESTEROIDAL SOBRE LA PROLIFERACION Y SUPERVIVENCIA CELULAR EN ENDOMETRIOS OBTENIDOS DE PACIENTES CON SINDROME DE OVARIO POLIQUISTICO (SOP)" FONDECYT (1050098) Proyecto 2005-2009 Coinvestigador(a)
PARTICIPACION DEL FACTOR DE CRECIMIENTO NERVIOSO(NGF) Y SU RELACION CON EL FACTOR DE CRECIMIENTO DEL EPITELIO VASCULAR(VEGF) EN LA ANGIOGENESIS DEL OVARIO. ESTUDIO EN OVARIO NORMAL Y CANCER EPITELIAL FONDECYT (1030661) Proyecto 2003-2006 Inv. Responsable
ESTUDIO DEL EFECTO ANTIPROLIFERATIVO Y APOPTOTICO DE ANALOGOS DE GnRH SOBRE CELULAS DE CANCER PROSTATICO HUMANO EN CULTIVOS BICAMERALES. INTERACCION CON NGF Y SUS RECEPTORES FONDECYT (1020969) Proyecto 2002-2005 Coinvestigador(a)


Role of Nerve Growth Factor (NGF) and miRNAs in Epithelial Ovarian Cancer Retamales-Ortega R.; Oróstica L.; Vera C.; Cuevas P.; Hernández A.; Hurtado I.; Vega M.; Romero C. Review ISI SCOPUS INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Role of nerve growth factor and its TRKA receptor in normal ovarian and epithelial ovarian cancer angiogenesis Vera C.; Tapia, V; Vega M.; Romero C. Review ISI SCOPUS JOURNAL OF OVARIAN RESEARCH (2014)

Carmen Romero

Jefe Laboratorio Endocrinología y Biología Reproductiva

Obstetricia y Ginecología

HOSPITAL CLÍNICO UNIVERSIDAD DE CHILE

Santiago, Chile

Maria Vega

Academico Profesora Titular

Obstetricia y Ginecologia Campus Norte

UNIVERSIDAD DE CHILE - FACULTAD DE MEDICINA

Santiago, Chile

Karla Kohan

Profesional de laboratorio

Instituto de Salud Pública

Santiago, Chile

Alfonso Paredes

UNIVERSIDAD DE CHILE

Santiago, Chile

Paulina Ormazábal

Docente investigador

Facultad de Ciencias para el cuidado de la Salud

Universidad San Sebastián

Santiago, Chile

Alfonso Paredes

Investigador principal

Bioquímica y Biología Molecular

University of Chile / Faculty of Chemical Sciences and Pharmacy

Santiago, Chile

Marcela Julio

Profesor Adjunto

Instituto de Química

PONTIFICIA UNIVERSIDAD CATÓLICA DE VALPARAISO

Valparaiso, Chile

Hernan Lara

Profesor Titular

Bioquimica y Biologia Molecular

U DE CHILE, FAC CIENCIAS QUIMICAS Y FARMACÉUTICAS

Santiago, Chile

ARTURO FERREIRA

FULL PROFESSOR, CHAIR IMMUNOLOGY DISCIPLINARY PROGRAM

IMMUNOLOGY

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

Pablo Caviedes

Full professor

ICBM

PROGRAMA DE FARMACOLOGÍA MOLECULAR Y CLÍNICA, ICBM, FAC. DE MEDICINA, U. DE CHILE

Santiago, Chile

Leonor Moyano

Jefe de Servicio

Anatomía Patológica

Instituto Nacional del Cáncer

Santiago, Chile

Lilian Jara

Titular Professor

Human Molecular Genetic

UNIVERSIDAD DE CHILE / FACULTAD DE MEDICINA

Santiago, Chile

Luis Leon

Head of Bioinformatics and Computational Biology

Technology

PhageLab

Santiago, Chile

Macarena Valladares

Profesor asociado

UNIVERSIDAD BERNARDO O'HIGGINS

Santiago, Chile

Lisette Leyton

Full Professor

Cell and Molecular Biology

FACULTAD DE MEDICINA UNIVERSIDAD DE CHILE

Santiago, Chile

SERGIO LAVANDERO

Director

Advanced Center for Chronic Diseases (ACCDiS)

UNIVERSIDAD DE CHILE, FAC CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

MARIA MOLINA

Director

Instituto de Ciencias Biomédicas

Universidad de Chile

INDEPENDENCIA, Chile

Soledad Henriquez

Profesor Asistente

INSTITUTO DE INVESTIGACIONES MATERNO INFANTIL, FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

Denisse Bravo

Associate Professor

Pathology and Oral Medicine

UNIVERSIDAD DE CHILE

Santiago, Chile

Daniela Parrau

Profesor asistente

Morfofunción

Universidad Diego Portales

Santiago, Chile

Hector Contreras

Academico

Oncologia Basico Clinica

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA, INSTITUTO DE CIENCIAS BIOMÉDICAS, PROGRAMA DE FISIOLOGÍA Y BIOFÍSICA

Santiago, Chile

Sebastián Illanes

professor, Director of Reproductive Biology Laboratory

Medicine

UNIVERSIDAD DE LOS ANDES

Santiago, Chile

Gino Corsini

Director Instituto Ciencias Biomédicas

Instituto de Ciencias Biomédicas

Universidad Autónoma de Chile

Santiago, Chile

JAVIER BRAVO

PROFESOR ADJUNTO

INSTITUTO DE QUÍMICA

PONTIFICIA UNIVERSIDAD CATÓLICA DE VALPARAISO

VALPARAÍSO, Chile

Luis Michea

PROFESOR ASOCIADO

PROGRAMA FISIOLOGIA Y BIOFISICA

UNIVERSIDAD DE CHILE

Santiago, Chile

Hernán Huerta

Asistente de Investigación

Centro de Biología Integrativa

Universidad Mayor de Chile

Santiago, Chile

ULISES URZUA

Assistant Professor

ICBM

UNIVERSIDAD DE CHILE

Santiago, Chile

JENNY FIEDLER

LAB. NEUROPLASTICIDAD Y NEUROGENETICA. DEPTO BIOQUIMICA Y BIOLOGÍA MOLECULAR. FAC. CIENCIAS QUÍMICAS Y FARMACÉUTICAS. UNIVERSIDAD DE CHILE

Santiago, Chile

Gareth Owen

Profesor Titular

Fisiologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Bredford Kerr

Profesor Asociado

CEBICEM

Universidad San Sebastián

Santiago, Chile

Yenny Muñoz

sin cargo

Particular

santiago, Chile

Rocío Retamales

Consultora de análisis genómicos

Freelance

Dresden, Alemania

RAMON SERRA

JEFE DE SERVICIO

GINECOLOGIA

HOSPITAL NAVAL FFAA

PUNTA ARENAS, Chile

Carmen Aurora Romero Osses

Líneas de Investigación

Educación

Bioquimica, UNIVERSIDAD DE CHILE. Chile, 1973

Biología de la Reproducción, UNIVERSIDAD DE CHILE. Chile, 1983

Neuro-Endocrinología del Ovario, OREGON HEALTH SCIENCES UNIVERSITY. Estados Unidos, 1999

Gestión en Salud, UNIVERSIDAD DE CHILE. Chile, 2000

Experiencia Académica

Profesor Titular Part Time

Docente en diferentes cursos de pre y post grado Full Time

Experiencia Profesional

Jefe Laboratorio de Endocrinología y Biología Reproductiva Hospital Clínico Universidad de Chile Full Time

Académico de Facultad de Ciencias Químicas y Farmacéuticas Part Time

WHO Fellow Full Time

WHO Fellow Full Time

Formación de Capital Humano

Difusión y Transferencia

Article (78)

Abstract (7)

EditorialMaterial (1)

Proyecto (12)

ROLE OF NERVE GROWTH FACTOR ON THE REGULATION OF MIRNAS 23B AND MIRNA145 AND INFLAMMATORY MOLECULES INVOLVED IN CELL PROLIFERATION AND TUMOR ANGIOGENESIS OF EPITHELIAL OVARIAN CANCER

Centro de estudios avanzados de enfermedades crónicas (ACCDiS)

Involvement of adiponectin in the regulation of endometrial metabolic function of obese women bearing polycystic ovarian syndrome and hiperinsulinism

Ovarian cancer initiation and spread in a syngeneic mouse model at estropausal state

Desarrollo de una plataforma tecnológica para análisis cuantitativos, cualitativo y de distribución subcelular de proteínas

"CONTRIBUTION OF TRKA RECEPTOR ISOFORMS TO THE CELLULAR PROLIFERATION AND ANGIOGENESIS OF EPITHELIAL OVARIAN CANCER=> POTENTIAL TARGETS FOR THERAPEUTIC INTERVENTION"

Contribution of trkA receptor isoforms to the cellular proliferation and angiogenesis of epithelial ovarian cancer=> Potential targets for therapeutic intervention.

EFECTO DE LA CONDICION HIPERANDROGENICA E HIPERINSULINICA SOBRE MOLECULAS REGULADORAS DE LA EXPRESION Y TRAFICO INTRACELULAR DEL TRANSPORTADOR DE GLUCOSA GLUT4 EN ENDOMETRIOS DE PACIENTES CON SINDROME DE OVARI POLIQUISTICO

PARTICIPACION DEL RECEPTOR trkA Y SU LIGANDO, EL FACTOR DE CRECIMIENTO NERVIOSO (NGF), EN LA GENESIS Y PROGRESION DEL CANCER OVARICO EPITELIAL.

"PARTICIPACION DEL MICROAMBIENTE ESTEROIDAL SOBRE LA PROLIFERACION Y SUPERVIVENCIA CELULAR EN ENDOMETRIOS OBTENIDOS DE PACIENTES CON SINDROME DE OVARIO POLIQUISTICO (SOP)"

PARTICIPACION DEL FACTOR DE CRECIMIENTO NERVIOSO(NGF) Y SU RELACION CON EL FACTOR DE CRECIMIENTO DEL EPITELIO VASCULAR(VEGF) EN LA ANGIOGENESIS DEL OVARIO. ESTUDIO EN OVARIO NORMAL Y CANCER EPITELIAL

ESTUDIO DEL EFECTO ANTIPROLIFERATIVO Y APOPTOTICO DE ANALOGOS DE GnRH SOBRE CELULAS DE CANCER PROSTATICO HUMANO EN CULTIVOS BICAMERALES. INTERACCION CON NGF Y SUS RECEPTORES

Review (2)