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ARTURO .Luis FERREIRA VIGOUROUX

FULL PROFESSOR, CHAIR IMMUNOLOGY DISCIPLINARY PROGRAM

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

Trypanosome cruzi calreticulin, infectivity, angiogenesis and tumor development.

IMMUNOLOGY, UNIVERSIDAD DE CHILE. Chile, 1982
Veterinarian, UNIVERSIDAD DE CHILE. Chile, 1968

Instructor Full Time

UNIVERSIDAD DE CHILE

FACULTY OF MEDICINE

Santiago, Chile

1969 - 1973
ASSISTANT PROFESSOR Full Time

UNIVERSIDAD DE CHILE

MEDICINE

Santiago, Chile

1974 - 1976
ASSOCIATE RESEARCH SCIENTIST Full Time

NEW YORK UNIVERSITY

MEDICINE

New York, Estados Unidos

1973 - 1977
RESEARCH SCIENTIST Full Time

NEW YORK UNIVERSITY

MEDICINE

New York, Estados Unidos

1977 - 1982
ASSOCIATE PROFESSOR Full Time

NEW YORK UNIVERSITY

MEDICINE

New York, Estados Unidos

1986 - 1986
ASSOCIATE PROFESSOR Full Time

UNIVERSIDAD DE CHILE

MEDICINE

Santiago, Chile

1986 - 1989
FULL PROFESSOR Full Time

UNIVERSIDAD DE CHILE

FACULTY OF VETERINARY AND ANIMAL SCIENCES

Santiago, Chile

1990 - 1997
ASSOCIATE PROFESSOR Full Time

NEW YORK UNIVERSITY

MEDICINE

New York, Estados Unidos

1982 - 1986
FULL PROFESSOR Full Time

UNIVERSIDAD DE CHILE

MEDICINE

Santiago, Chile

1997 - A la fecha

Full Professor Full Time

Universidad de Chile

Chile

1990 - A la fecha

Undergraduates Thesis Director
Elizabeth Pombet, Carolina Bustos, Marcia López, Rodrigo Maass, Claudio Cortés, Leonardo Paredes, Katherine Marcelain, Adam Aguirre, Alejandro Escobar,
Tamara Hermosilla, Claudio Pérez, Miguel Mejías, Lorena Aguilar, Galia Ramírez, Pamela Williams, Ismael Maldonado, Margarita Rodríguez, Katherine Weinberger, Francisca Coddou, Leonora Duaso, Fernando Vivanco, Eduardo Sosoniuk.

Master Thesis Director
Janina Subía, Heriberto Arévalo, Violeta Pavéz, Víctor Toledo, Haydeé Gallardo, Javier Pizarro.

Doctorals Thesis Director
Julio Scharfstein, Juan Carlos Aguillón Gutiérrez, María Carmen Molina Sampaio, Viviana Ferreira Aranguren, Carolina Hager Ribeiro, Nandy López Bartolucci, Carolina Valck Calderón, Galia Andréa Ramírez Toloza, Lorena Aguilar Guzmán, Andrea González, Paula Abello, Katherine Weinberger, Jaime Peña, Carlos Rosas .

Doctoral Thesis Co-Director
Rodolfo Paredes, Carolina Cabezón, Carlos Saffie.

Pos-Doctoral Students
Santiago Rodríguez de Córdoba, Ferruccio Santoro, Louis Schofield, Daniel Eichinger.

PhD Students
Carolina Vera, Eduardo Sosoniuk, Pamela Cruz, Myriam Pujol

Communication of Science to Society and Proposed Mechanisms and Activities to Reach these Goals:
Proyecto Anillos 2017 (in Referral procedures as of July 2017)
4.1. To the general public: i). One interview per year of execution, in Radio University of Chile and current newspapers, involving researchers and students in the project; ii). Lectures and conferences for high school students as part of the "Week of Science" or as part of “Future Student of the Faculty of Medicine of the University of Chile”; iii). Ad hoc project page, at the ICBM electronic portal; 4.2. To specialized audience: i). Participation in at least 4 National and International scientific events, under the sponsorship of relevant scientific societies; ii). Organization of an International Workshop (tentative title: “Deleterious and Beneficial Host-Parasite Interactions”).

President of Asociación Latinoamericana de Inmunología

ALAI

Chile, 1990

President of Asociación Latinoamericana de Inmunología
Head of PhD Committee

Facultad de Medicina Universidad de Chile

Chile, 2000

Head of PhD Committee
Award for Excellent Academic

Facultad de Medicina Universidad de Chile

Chile, 2010

Award for Excellent Academic
Vice President Superior Committee of Academic Evaluation

UNIVERSIDAD DE CHILE

Chile, 2004

Vice President Superior Committee of Academic Evaluation
Research Director of Instituto de Ciencias Biomédicas

Instituto de Ciencias Biomédicas

Chile, 2007

Director of Instituto de Ciencias Biomédicas
Honorary Visiting Professor

Leicester University

Reino Unido, 2012

Honorary Visiting Professor
Vice-Dean

Facultad de Medicina Universidad de Chile

Chile, 2014

Vice-Dean


Exogenous Calreticulin, incorporated onto non-infective Trypanosoma cruzi epimastigotes, promotes their internalization into mammal host cells Sosoniuk-Roche, Eduardo; Pizarro-Bäuerlea, Javier; Weinberger, Katherine; Michalak, Marek Article SCOPUS Immunobiology (2017)
Molluskan Hemocyanins Activate the Classical Pathway of the Human Complement System through Natural Antibodies Pizarro-Bauerle, Javier; Sosoniuk-Roche, Eduardo Article ISI SCOPUS FRONTIERS IN IMMUNOLOGY (2017)
The nerve growth factor alters calreticulin translocation from the endoplasmic reticulum to the cell surface and its signaling pathway in epithelial ovarian cancer cells Article ISI SCOPUS INTERNATIONAL JOURNAL OF ONCOLOGY (2017)
Does native Trypanosoma cruzi calreticulin mediate growth inhibition of a mammary tumor during infection? Abello-Cáceres, et al Article ISI SCOPUS BMC CANCER (2016)
Feeding profile of Mepraia spinolai, a sylvatic vector of Chagas disease in Chile Chacón, F; Quiroga, J.F. Article ISI SCOPUS ACTA TROPICA (2016)
Is the Antitumor Property of Trypanosoma cruzi Infection Mediated by Its Calreticulin? Ramirez-Toloza, et al Article ISI FRONTIERS IN IMMUNOLOGY (2016)
Structures of parasite calreticulins provide insights into their flexibility and dual carbohydrate/peptide-binding properties Moreau C, et al Article ISI SCOPUS IUCRJ (2016)
Triatoma infestans Calreticulin: Gene Cloning and Expression of a Main Domain That Interacts with the Host Complement System. Weinberger et al Article ISI The American Journal of Tropical Medicine and Hygiene (2016)
Deficiency in Mannose-Binding Lectin-Associated Serine Protease-2 Does Not Increase Susceptibility to Trypanosoma cruzi Infection Ribeiro, C.H.; Lynch N.J.; Stover C.M.; Ali Y.M.; Valck C.; Noya-Leal F.; Schwaeble W.J.; Ferreira A. Article ISI SCOPUS AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE (2015)
Trypanosoma cruzi Calreticulin Topographical Variations in Parasites Infecting Murine Macrophages González A; Valck C.; Sánchez G; Hartel, S; Mansilla, J; Ramírez, G; Fernandez, MS; Galanti N.; Ferreira A. Article ISI SCOPUS American Journal of Tropical Medicine and Hygiene (2015)
A Monoallelic Deletion of the TcCRT Gene Increases the Attenuation of a Cultured Trypanosoma cruzi Strain, Protecting Against an in Vivo Virulent Challenge Article ISI PLOS NEGLECTED TROPICAL DISEASES (2014)
Celecoxib decreases growth and angiogenesis and promotes apoptosis in a tumor cell line resistant to chemotherapy Article ISI BIOLOGICAL RESEARCH (2014)
Comparative effect of human and Trypanosoma cruzi calreticulin in wound healing Ignacio Arias J.; Sepulveda, C; Bravo, P; Hamilton-West, C; Maldonado I.; Ferreira A. Article SCOPUS JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2014)
Human Survivin and Tripanosoma cruzi Calreticulin Act in Synergy Against a Murine Melanoma in Vivo Article ISI PLoS One (2014)
Tax Posttranslational Modifications and Interaction with Calreticulin in MT-2 Cells and Human T Cell Lymphotropic Virus Type-I-Associated Myelopathy/Tropical Spastic Paraparesis Patients Article ISI AIDS Research and Human Retroviruses (2014)
Trypanosoma cruzi calreticulin inhibits the complement lectin pathway activation by direct interaction with L-Ficolin Sosoniuk, E., Vallejos, G., Kenawy, H., Gaboriaud, C., Thielens, N., Fujita, T., Schwaeble, W., Valck, C., A. Ferreira. Article ISI SCOPUS MOLECULAR IMMUNOLOGY (2014)
The Interaction of clasical complemento component C1 with parasite and host calreticuin mediates Trypanosoma cruzi infection of human placenta Castillo, C et al Article ISI PLOS NEGLECTED TROPICAL DISEASES (2013)
Trypanosoma cruzi carrying a monoallelic deletion of the calreticulin (TcCRT) gene are susceptible to complement mediated killing and defective in their metacyclogenesis Valdez, FJS; Brandan, CP; Labriola, C; Ferreira A.; Basombrio, MA Article ISI SCOPUS Molecular Immunology (2013)
Nerve Growth Factor Induces the Expression of Chaperone Protein Calreticulin in Human Epithelial Ovarian Cells Vera C.; Tapia, V; Kohan, K; Gabler F.; Ferreira A.; Selman A.; Vega M.; Romero C. Article ISI SCOPUS Hormone and Metabolic Research (2012)
Bovine (Bos taurus) Humoral Immune Response Against Echinococcus granulosus and Hydatid Cyst Infertility Paredes, R.; Godoy, P; Rodríguez, B.; Garcia, MP; Cabezon C.; Cabrera G.; Jimenez, V; Hellman, U; Saenz, L; Ferreira A.; et al. Article ISI SCOPUS Journal of Cellular Biochemistry (2011)
Heat-Shock Induction of Tumor-Derived Danger Signals Mediates Rapid Monocyte Differentiation into Clinically Effective Dendritic Cells Aguilera R.; Saffie C; Tittarelli, A; Ramirez M.; Reyes, D; Pereda, C; Hevia D; Garcia, T.; Salazar, L; Ferreira A.; et al. Article ISI SCOPUS Clinical Cancer Research (2011)
Trypanosoma cruzi calreticulin: A novel virulence factor that binds complement C1 on the parasite surface and promotes infectivity Ramírez, G; Valck C.; Molina, MC; López N.; Sánchez G; Ferreira, VP; Billetta, R; Aguilar, L; Maldonado I.; Cattan, P; et al. Article ISI SCOPUS Immunobiology (2011)
Antiangiogenic and Antitumor Effects of Trypanosoma cruzi Calreticulin Valck C.; Ramírez, G; Rodríguez, M.; Ribeiro, C; Orellana J.; Maldonado I.; Albini, A; ANACONA, D; Lemus D.; Aguilar, L; et al. Article ISI SCOPUS PLOS NEGLECTED TROPICAL DISEASES (2010)
Betamethasone inhibits tumor development, microvessel density and prolongs survival in mice with a multiresistant adenocarcinoma TA3 Garrido, O; Letelier R.; Rosas, C; Fuenzalida, M; Ferreira A.; Lemus D. Article ISI SCIELO SCOPUS Biological Research (2010)
Comparative in vivo antiangiogenic effects of calreticulin from Trypanosoma cruzi and Homo sapiens sapiens Toledo, V.; Ramírez, G; Valck C.; López N.; Maldonado I.; Aguilar, L; Lemus D.; Ferreira A. Article ISI SCIELO SCOPUS Biological Research (2010)
Molecular mechanisms involved in the inactivation of the first component of human complement by Trypanosoma cruzi calreticulin Valck C.; Ramírez, G; López N.; Maldonado I.; Sánchez G; Ferreira, VP; Schwaeble, W; Ferreira A. Article ISI SCOPUS Molecular Immunology (2010)
Trypanosoma cruzi: In vitro effect of aspirin with nifurtimox and benznidazole Lopez-Munoz, R; Faundez, M; Klein, S; Escanilla, S; Torres, G; Lee-Liu, D; Ferreira J.; Kemmerling U.; Orellana M.; Morello A.; et al. Article ISI SCOPUS Experimental Parasitology (2010)
Trypanosoma cruzi calreticulin: A possible role in Chagas' disease autoimmunity Valck, CE; Molina, MC; Aguilar, L; Rodríguez, M.; Maldonado I.; Martínez R; Gonzalez, C.; Troncoso R.; Lavandero S.; Gingras, AR; et al. Article ISI SCOPUS MOLECULAR IMMUNOLOGY (2009)
Assessment of the IgG index in dogs by indirect immunoenzimatic assays as diagnostic tool for inflammatory diseases of central nervous system Mejias, M; Molina, MC; Ferreira A. Article ISI SCOPUS RESEARCH IN VETERINARY SCIENCE (2008)
Echinococcus granulosus calreticulin: Molecular characterization and hydatid cyst localization Cabezon C.; Cabrera G.; Paredes, R.; Ferreira A.; Galanti N. Article ISI SCOPUS MOLECULAR IMMUNOLOGY (2008)
Melanocortin 1 receptor is expressed by uveal malignant melanoma and can be considered a new target for diagnosis and immunotherapy López MN; Pereda, C; Ramirez M.; Mendoza-Naranjo, A; Serrano A.; Ferreira A.; Poblete, R; Katergis, AM; Kiessling R.; SALAZAR ONFRAY F Article ISI SCOPUS INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2007)
Methotrexate regulates the expression of glucocorticoid receptor alpha and beta isoforms in normal human peripheral mononuclear cells and human lymphocyte cell lines in vitro Alvarez C.; Henriquez, J.; Salas K; Molina, ML; Ferreira A.; Gatica H. Article ISI SCOPUS MOLECULAR IMMUNOLOGY (2007)
Naked DNA immunization as an approach to target the generic tumor antigen survivin induces humoral and cellular immune responses in mice Lladser, A; Párraga M.; Quevedo, L.; Molina, MC; Silva, S; Ferreira A.; Billetta, R; Quest, AFG Article ISI SCOPUS IMMUNOBIOLOGY (2006)
An in vivo role for Trypanosoma cruzi calreticulin in antiangiogenesis Article ISI SCOPUS MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2005)
Does Trypanosoma cruzi calreticulin modulate the complement system and angiogenesis? Ferreira, V; Molina, MC; Schwaeble, W; Lemus D.; Ferreira A. Article ISI SCOPUS TRENDS IN PARASITOLOGY (2005)
F(ab')2 antibody fragments against Trypanosoma cruzi calreticulin inhibit its interaction with the first component of human complement Aguilar, L; Ramírez, G; Valck C.; Molina, MC; Rojas A.; Schwaeble, W; Ferreira, V; Ferreira A. Article ISI SCIELO SCOPUS BIOLOGICAL RESEARCH (2005)
A SIMPLE IMMUNOMETRIC ASSAY TO ASSESS THE FEEDING HABITS OF MEPRAI SPINOLAI, A TRYPANOSOMA CRUZI VECTOR Molina, maria; Ferreira, Luis; Cruzat, Loreto; Cattan, Pedro; Canals, Mauricio; Aguillon, Juan Article PARASITOLOGY RESEARCH (2004)
The -308 polymorphism in the promotor region of the tumor necrosis factor-alpha (TNF-alpha) gene and ex vivo lipopolysaccharide-induced TNF-alpha expression in patients with aggresive peridontitis and/or type 1 diabetes mellitus Pérez, C.; Pavez, V; Aguirre A.; Cruzat, A; Contreras-Levicoy, J; Dotte, A; Aravena, O; Salazar, L; Catalan, D; Cuenca J.; et al. Article ISI European Cytokine Network (2004)
The classical activation pathway of the human complement system is specifically inhibited by calreticulin from Trypanosoma cruzi Ferreira, V; Valck C.; Sánchez G; Gingras, A; Tzima, S; Molina, MC; Simó R.; Schwaeble, W; Ferreira A. Article ISI SCOPUS JOURNAL OF IMMUNOLOGY (2004)
An anti-human recombinant tumor necrosis factor alpha (TNF alpha) monoclonal antibody recognizes an epitope in feline TNF alpha Aguirre A.; Escobar A.; Ferreira, V; Molina, MC; Ferreira A. Article ISI VETERINARY RESEARCH (2003)
Evaluation of tumor necrosis factor alpha production in ex vivo short term cultured whole blood from women with polycystic ovary syndrome Aguirre A.; Romero C.; Miranda, C.; Molina, MC; Ferreira A. Article ISI SCOPUS European Cytokine Network (2002)
PARASITE CALRETICULIN: POSSIBLE ROLES IN THE PARASITE/HOST INTERFACE Valck, Carolina.; Rojas, Alvaro; Molina, maria; Ferreira, Luis; Ferreira, Viviana Article Inmunologia (2002)
Blood host sources of Mepraia spinolai (Heteroptera : Reduviidae), wild vector of Chagas disease in Chile Canals M.; Cruzat, L.; Molina, MC; Ferreira A. Article ISI JOURNAL OF MEDICAL ENTOMOLOGY (2001)
Daily production of human tumor necrosis factor in LPS-stimulated ex vivo blood culture assays Escobar A.; Ferreira, V; Aguirre A.; Ferreira L.; Molina, MC; Ferreira A. Article ISI SCOPUS European Cytokine Network (2001)
Development of an immunoenzymatic assay for the detection of human antibodies against Trypanosoma cruzi calreticulin, an immunodominant antigen Marcelain, K; Colombo, A; Molina, MC; Ferreira L.; Lorca M.; Ferreira A. Article ISI SCOPUS ACTA TROPICA (2000)
Tc45, a dimorphic Trypanosoma cruzi immunogen with variable chromosomal localization, is calreticulin Ferreira L.; Pérez, C.; Colombo, A; Molina, MC; Wallace A.; Solari, A; Carvallo, P.; Galindo, M; Galanti N.; Orn, A; et al. Article ISI AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE (2000)
Trypanosoma cruzi: H2 complex and genetic background influence on the humoral immune response against epimastigotes Hermosilla T.; Molina, MC; Morello A.; Repetto Y; Orn, A; Ferreira A. Article ISI SCOPUS INTERNATIONAL JOURNAL FOR PARASITOLOGY (2000)
Polyclonal antibodies anti-salmon immunoglobulins; potential tools for diagnosis Anticuerpos policlonales antiinmunoglobulinas de salmón; herramientas potenciales para diagnóstico Aguillon, J.C.; Colombo, A; Molina, M. C.; Ferreira A.; Smith P. Article ARCHIVOS DE MEDICINA VETERINARIA (1997)
Recognition of an immunogenetically selected Trypanosoma cruzi antigen by seropositive chagasic human sera Aguillon, J.C.; Molina, M. C.; Colombo, A; Cortes C.; Hermosilla T.; Carreño P.; Ferreira A.; Harris R.; Orn, A Article ACTA TROPICA (1997)
Generation and evaluation of a monoclonal antibody anti-pili K99 from enteropathogenic Escherichia coli Generación y evaluación de un anticuerpo monoclonal anti-pili K99 de Escherichia coli enteropatógena Cortes C.; Vallejos P.; Bustos C.; Molina, M. C.; Aguillon, J.C.; Ferreira A.; Zurita, L Article ARCHIVOS DE MEDICINA VETERINARIA (1996)
Immunomodulation of LPS ability to induce the local Shwartzman reaction Aguillon, J.C.; Ferreira, V; Núñez E.; Paredes, L.; Molina, M. C.; Colombo, A; Hermosilla T.; Ferreira A. Article SCANDINAVIAN JOURNAL OF IMMUNOLOGY (1996)
Antigenic Recognition in Ovines Naturally Infected with Fasciola hepatica. Monitoring Through a Western Blotting Gorman T et al Article ISI ARCHIVOS DE MEDICINA VETERINARIA (1995)
Humoral Immune Response Anti K99 Pilus from Enterotoxigenic Escherichia coli in Experimentally Inoculated Calves Article ISI BIOLOGICAL RESEARCH (1995)
Purification and Preliminary Sequencing of Tc45, an Immunodominant Trypanosoma cruzi Antigen: Absence of Homology with Cruzipain, Cruzain, and a 46-Kilodalton Protein. Article ISI AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE (1995)
Radiolabeling of Small Peptides Bound to a Solid Phase. Article ISI ANALYTICAL BIOCHEMISTRY (1995)
ELISA to Determine Anti-K99 Pilus Antibody in the Sera of Normal and Diarrhoeic Calves Article ISI VETERINARY MICROBIOLOGY (1994)
A Simple Method for Negative and Positive Selection of Murine and Human IgM-Bearing Lymphocytes Based on the Use of Antibody-Coated Silica Microparticles Article ISI JOURNAL OF IMMUNOLOGICAL METHODS (1993)
Transfer of IgG from Serum to Lachrymal Fluid in Chickens Article ISI Avian Diseases (1993)
Soybean proteins: Alternative Blocking Agents for Immunoassays Using Nitrocellulose or Plastic Solid Phases Article ISI BIOLOGICAL RESEARCH (1992)
An Immunogenetically Defined and Immunodominant Trypanosoma cruzi Antigen Article ISI AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE (1991)
Binding and Production of Insulin Like Growth Factor I in Rat Mammary Gland Article ISI Comparative Biochemistry and Physiology -- Part A: Physiology (1991)
Octadecyl silica: A solid Phase for Protein Purification by Immunoadsorption Article ISI ANALYTICAL BIOCHEMISTRY (1991)
Nonlytic Antibodies in H2 Controlled Resistance to Acute Infection with Trypanosoma cruzi Article ISI BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH (1990)
Use of DNA Probes to Detect Cellular Immunity Against Intracellular Parasitism Ferreira A. Article ISI ARCHIVOS DE BIOLOGIA Y MEDICINA EXPERIMENTALES (1990)
A Non-Conventional Solid Phase for Immunoradiometric Assays of Potential Use in the Diagnosis of Chagas' Disease Article ISI MEMORIAS DO INSTITUTO OSWALDO CRUZ (1988)
Use of Octadecylsilica as an alternative Non-Conventional Solid Phase in Immunoradiometric Assays. Article ISI JOURNAL OF IMMUNOLOGICAL METHODS (1988)
Anti-Malarial Activity of Alpha Tumor Factor and Gamma-Interferon Schofield L, et al Article Federation Proceedings (1987)
Gamma Interferon, CD8+ T Cells and Antibodies Required for Immunity to Malaria Sporozoites Article ISI NATURE (1987)
Interferon Inhibits the Intrahepatocytic Development of Malaria Parasites in vitro Article ISI JOURNAL OF IMMUNOLOGY (1987)
Mechanism of Escape of Exoerythrocytic Forms (EEF) of Malaria Parasites from the Inhibitory Effects of Interferon Y. Article ISI JOURNAL OF IMMUNOLOGY (1987)
Use of a DNA Probe to Measure the Neutralization of Plasmodium berghei Sporozoites by a Monoclonal Antibody Article ISI JOURNAL OF IMMUNOLOGY (1987)
Infectivity of Plasmodium berghei Sporozoites Measured with a DNA Probe Article ISI Molecular and Biochemical Parasitology (1986)
Inhibition of Development of Exoerythrocytic Forms of Malaria Parasites by Gamma Interferon. Article ISI SCIENCE (1986)
Multiple C4/Slp Genes Distinguished by Expression after Transfection Article ISI MOLECULAR AND CELLULAR BIOLOGY (1986)
Conserved Group-Specific Epitopes of the Circumsporozoite Proteins Revealed by Antibodies to Synthetic Peptides Article ISI JOURNAL OF IMMUNOLOGY (1985)
Does the Mouse C4-Binding Protein Gene (C4-bp) map in the H2 region? Article ISI IMMUNOGENETICS (1985)
Multiple NonRepeated Epitopes on the Circumsporozoite Protein of Plasmodium knowlesi. Article ISI Molecular and Biochemical Parasitology (1985)
High Resolution Isoelectric Focusing of Immunoprecipitated Proteins Under Denaturing Conditions. A Simple Analytical Method Applied to the Study of Complement Component Polymorphisms Article ISI JOURNAL OF IMMUNOLOGICAL METHODS (1984)
Genetic Polymorphism of Human C4-Binding Protein Article ISI JOURNAL OF IMMUNOLOGY (1983)
Murine Sex-Limited Protein (Slp) Antigenic Sites in Human Complement Component C4 Article ISI IMMUNOGENETICS (1983)
Structural Similarities among the Protective Antigens of Sporozoites from Different Species of Malaria Parasites Article ISI JOURNAL OF BIOLOGICAL CHEMISTRY (1983)
The Murine Sex-Limited protein (Slp): Reassessment of its Sex Limitation Article ISI JOURNAL OF IMMUNOLOGY (1982)
A Simplified Two-Dimensional Electrophoretic Technique Ferreira, A., Eichinger D. Article Pubmed J Immunol Methods. (1981)
cis Interacting Genes in the S Region of the Murine Major Histocompatibility Complex Michaelson, J., A. Ferreira, A., Nussenzweig, V. Article Pubmed NATURE (1981)
Functional Variations in H2-Duplicated Genes Ferreira A. Article ISI BIOLOGICAL RESEARCH (1981)
A Polymorphism of the gamma Chain of Mouse C4 Controlled by the S Region of the Major Histocompatibility Article Pubmed J. Immunol. (1980)
H-2 Controlled Polymorphism of the gamma Chain of Slp (Sex-Limited Protein) Article ISI IMMUNOBIOLOGY (1980)
Polymorphism of the gamma Chains of Murine Ss (C4) and Slp Proteins Article Pubmed IMMUNOBIOLOGY (1980)
The Murine H-2.7 Specificity is an Antigenic Determinant of C4d, a Fragment of the Fourth Component of the Complement System Article Pubmed IMMUNOBIOLOGY (1980)
Three-Step Purification of its C4c Fragment and Production of a Monospecific Antiserum Article Pubmed J. Immunol. (1979)
Human C4-Binding Protein. I Isolation and Characterization. Article Pubmed J. Immunol. (1978)
Presence of a C4-Binding Protein (C4-bp) in Human Serum Scharfstein, J., Ferreira, A., ..., Nussenzweig, V.. Article Journal of Immunology J. Immunol. (1978)
Presence of a C4-Binding Protein in Human Serum Scharfstein J, et al Article ISI JOURNAL OF IMMUNOLOGY (1978)
Purification and Characterization of a Mouse Serum Protein with Specific Binding Affinity for C4 (Ss Protein). Ferreira A, et al. Article ISI JOURNAL OF IMMUNOLOGY (1978)
Structural and Functional Differences Between of the H-2 Controlled Ss and Slp Proteins Article Pubmed j Exp Med (1978)
Testosterone Control of Serum Levels of C4-Binding Protein in Mice Article Pubmed J. Immunol. (1978)
Purification and Characterization of Mouse Serum Protein with Specific Binding Affinity for C4 (Ss protein) Article Pubmed j Exp Med (1977)
Control of C3 Levels in Mice During Ontogeny by a Gene in the Central Region of the H-2 complex Ferreira, A., Nussenzweig, V. Article Pubmed NATURE (1976)
Genetic Control of C3 Levels in Mice Ferreira, A., Nussenzweig, V. Article Journal of Immunology J. Immunol. (1976)
Influence of H-2 on the Ontogenesis of a Spleen Cell Population which Lacks C3 Receptors and Thy 1 Antigen Article Pubmed J. Immunol. (1976)
Mechanism of Solubilization of Immune Aggregates by Complement. Implications for Immunopathology Takahashi M, et al. Article ISI IMMUNOLOGICAL REVIEWS (1976)
Relationship Between 4a and 4b HLA-Determined Specificites and C3 Receptors of Leukocyte Membrane Ferreira, A., Nussenzweig, V. Article Pubmed Eur J Immunol (1976)
Genetic Linkage Between Serum Levels of the Third Component of Complement and the H-2 Complex Article Pubmed j Exp Med (1975)
Effects of Cortisone on H2 Agglutinin Response in Normal and Thymectomized Adult Mice Ramos, A., ..., Ferreira, .A., Hoecker, G. Article Pubmed IMMUNOLOGY (1973)
Lack of Correlation Between the Effects of Cortisone on Mouse Spleen Plaque Forming Cells and Circulating Anti-Sheep Red Blood Cell Haemolysins Article Pubmed IMMUNOLOGY (1973)
Restrictions of Antibody Production Against the H-2 Antigenic Complex. Transplantation Proceedings Article Pubmed Transplant Proc . (1970)
Thymectomy in the Adult Mouse Article Pubmed TRANSPLANTATION (1970)


A Tribute to Professor Gustavo Hoecker Salas Ferreira, Arturo; Valenzuela, Carlos; Santos, Manuel J. Editorial SCIELO BIOLOGICAL RESEARCH (2010)


Immunology in Latin America - Preface Ferreira A. EditorialMaterial ISI IMMUNOBIOLOGY (2006)


Citómetro de Flujo Multiparamétrico Ferreira A. Proyecto (2015)
Trypanosoma cruzi Calreticulin in virtue of its antiangiogenic properties, Inhibits Tumor Growth in Experimental Models Ferreira A.; Valck C. Proyecto (2013)
Trypanosoma cruzi Calreticulin: Interplay with the Complement System and Angiogenesis Ferreira A. Proyecto (2009)
Controlled alteration of antioxidative metabolism as a Strategy to Modulate Trypanosoma cruzi Infectivity and Antiangiogenic Effects : An Integral of two Bicentennial rings Research Ferreira A. Proyecto (2008)
Advanced Center for Training and Research in the Design of Pharmacological and Immunological Strategies for the Control of Parasitic and Neoplastic Aggresions Ferreira A. Proyecto (2007)
Chagas` Disease: Control of Virulence and Infecivity of Trypanosoma cruzi with Products of Natural, Synthetic and Immunologic Origin Ferreira A. Proyecto (2005)
Targeting by Genetic (DNA) Immunization of the Survivin Inhibitor of Apoptosis, a Generic Tumor Associated Antigen Ferreira A. Proyecto (2003)
National Network of Doctoral Programs in Molecular Biosciences : A Multidisciplinary Joint, Inter, Horizontal and Dynamics Ferreira A. Proyecto (2002)
Role of Trypanosoma cruzi Calreticulin in Modulation of Host / Parasite Interaction Ferreira A. Proyecto (2001)
Mecanismos de Acción de Inmunoglobulinas Endovenosos en Enfermedades Autoinmunes Ferreira A. Proyecto (1998)
Detección, Caracterización y Producción de Antígenos de Trypanosoma cruzi: El Modelo de Tc45, un Nuevo Inmunógeno Ferreira A. Proyecto (1997)
Promoción de Transferencia Inmunobiotecnológica Ferreira A. Proyecto (1996)
Red Latinoamericana de Centros de Inmunología Ferreira A. Proyecto (1996)
Centro de Referencia para la Producción de Reactivos Inmunológicos, Expansión in vitro de Anticuerpos Monoclonales y Desarrollo de Metodología Inmunológica Relevante Ferreira A. Proyecto (1994)
Detección Caracterización y producción de Antígenos de Trypanosoma cruzi, Inmunogenéticamente Definidos Ferreira A. Proyecto (1994)
Programa Regional de Biotecnología. Programa de las Naciones Unidas Para el Desarrollo. Grant de Entrenamiento Ferreira A. Proyecto (1991)
Detección y Caracterización Molecular de Algunos Antígenos Trypanosoma cruzi; Potencial en el Diagnóstico/Pronóstico de la Enfermedad de Chagas. Ferreira A. Proyecto (1990)
Development and standardization of a non conventional immunologic approach for the Diagnosis of Chagas' Disease Ferreira A. Proyecto (1990)
Molecular aspects of immunogenetic resistance to Trypanosoma cruzi Ferreira A. Proyecto (1990)
Desarrollo de Metodología Inmunoquímica para el Diagnóstico de la Enfermedad de Chagas y de la Tuberculosis Ferreira A. Proyecto (1988)
Desarrollo e Imple¬mentación de Tecnología Inmunoquímica Moderna para la Detección de Moléculas de Importan¬cia Biomédica. Aplica¬ción al Diagnóstico de la Enfermedad de Chagas y de la Tuberculosis Ferreira A. Proyecto (1988)
Identificación y caracterización de antígenos de Trypanosoma cruzi con capacidad inmunogénica protectora en cepas de ratones resistentes y sensibles a la enfermedad de Chagas Ferreira A. Proyecto (1987)
Immunospecific regions of the protective antigens of Plasmodium knowles Ferreira A. Proyecto (1985)
The use of specific DNA probes to detect and quantitative malaria exoerythocytic forms Ferreira A. Proyecto (1985)
Clinical and Basic Biology of Chagas’ Disease Ferreira A. Proyecto (0)
Programa de Intercambio Ferreira A. Proyecto (0)


Gene-deleted live-attenuated Trypanosoma cruzi parasites as vaccines to protect against Chagas disease Sanchez-Valdez, FJ; Brandan, CP; Ferreira A.; Basombrio, MA Review ISI SCOPUS Expert Review of Vaccines (2015)
Is it all that bad when living with an intracellular protozoan?The role of Trypanosoma cruzi calreticulin in angiogenesis and tumor growth Ramirez-Toloza, G; Aguilar-Guzman, L; Valck C.; Abello P; Ferreira A. Review ISI FRONTIERS IN ONCOLOGY (2015)
Roles of Trypanosoma cruzi calreticulin in parasite-host interactions and in tumor growth Ramírez, G; Valck C.; Aguilar, L; Kemmerling U.; Lopez-Munoz, R; Cabrera G.; Morello A.; Ferreira J.; Maya J.D.; Galanti N.; et al. Review ISI SCOPUS Molecular Immunology (2012)
Extracellular Trypanosoma cruzi calreticulin in the host-parasite interplay Ramírez, G; Valck C.; Ferreira, VP; López N.; Ferreira A. Review ISI SCOPUS Trends in Parasitology (2011)
Mode of action of natural and synthetic drugs against Trypanosoma cruzi and their interaction with the mammalian host Iturriaga-Vasquez, P; Ferreira J.; Faundez, M; Galanti N.; Ferreira A.; Morello A. Review ISI COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY (2007)
Role of calreticulin from parasites in its interaction with vertebrate hosts Ferreira, V; Molina, MC; Valck C.; Rojas A.; Aguilar, L; Ramírez, G; Schwaeble, W; Ferreira A. Review ISI SCOPUS MOLECULAR IMMUNOLOGY (2004)

MARIA MOLINA

Director

Instituto de Ciencias Biomédicas

Universidad de Chile

INDEPENDENCIA, Chile

Steffen Härtel

Full Professor

Instituto de Ciencias Biomédicas

University of Chile

Santiago, Chile

Alvaro Lladser

Professor, Principal Investigator

FUNDACIÓN CIENCIA PARA LA VIDA

Santiago, Chile

Jose Arias

Full Professor

Animal Biology

FACULTAD DE CIENCIAS VETERINARIAS, UNIVERSIDAD DE CHILE

Santiago, Chile

José Arias

Asistant Profesor

Clinical Sciences

FAC. CS. VET. Y PEC., UNIVERSIDAD DE CHILE

Santiago, Chile

Mauricio Canals

PROFESOR TITULAR

MEDICINA

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA

SANTIAGO, Chile

Carlos Bustos

Profesor Titular

Química

INSTITUTO DE CIENCIAS QUÍMICAS, FACULTAD DE CIENCIAS, UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

Marcela Hermoso

Full Professor

School of Medicine

UNIVERSIDAD DE CHILE

Santiago, Chile

SERGIO LAVANDERO

Director

Advanced Center for Chronic Diseases (ACCDiS)

UNIVERSIDAD DE CHILE, FAC CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

Carmen Romero

Jefe Laboratorio Endocrinología y Biología Reproductiva

Obstetricia y Ginecología

HOSPITAL CLÍNICO UNIVERSIDAD DE CHILE

Santiago, Chile

RODOLFO PAREDES

Medical Education and Clinical Simulation Director

Academic Vice Rectory

UNIVERDAD ANDRÉS BELLO

Santiago, Chile

Katherine Marcelain

Profesora Asociada

Oncología Básico Clínica

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA

Santiago, Chile

Lorena Salazar

Profesora Asistente

Instituto de Ciencias Biomédicas

Universidad Autónoma de Chile

Lampa, Chile

JUAN AGUILLON

PROFESSOR

IMMUNOLOGY PROGRAM

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

Jorge Ferreira

Director

Clinic and Molecular Farmacology

UNIVERSIDAD DE CHILE , FACULTAD DE MEDICINA, ICBM

Santiago, Chile

Juan Maya

Full Professor

Biomedical Sciences Institute

UNIVERSIDAD DE CHILE

Santiago, Chile

Norbel Galanti

Full Professor

ICBM

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA, INSTITUTO DE CIENCIAS BIOMÉDICAS, PROGRAMA DE BIOLOGÍA CELULAR Y MOLECULAR

Santiago, Chile

Gonzalo Cabrera

Academic

Cell and Molecular Biology

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

OCTAVIO ARAVENA

Gestión I+D

I+D+i

Comisión Chilena de Energía Nuclear

Santiago, Chile

Alicia Colombo

Profesora Asociada/Director Científico Biobanco de Tejidos y Fluidos de la Universidad de Chile

Departamento de Anatomía Patológica

Universidad de Chile

Santiago, Chile

Mario Párraga

PROFESOR TITULAR

ANATOMÍA

UNIVERSIDAD DE VALPARAÍSO

Reñaca, Chile

Alexis Kalergis

Full Professor

Microbiología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE. FACULTAD DE CIENCIAS BIOLÓGICAS

Santiago, Chile

Leonardo Sáenz

Profesor Asociado

Ciencias Biológicas Animales

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS VETERINARIAS Y PECUARIAS

Santiago, Chile

pedro cattan

full professor

ciencias biologicas animales

UNIVERSIDAD DE CHILE; FACULTAD DE CIENCIAS VETERINARIAS Y PECUARIAS

santiago, Chile

Patricio Iturriaga

Profesor Asociado A

Ciencias Quimicas y Recursos Naturales

UNIVERSIDAD DE LA FRONTERA

Temuco, Chile

María Becker

Scientific Director, President

Research and Development

FUNDACIÓN CIENCIA Y TECNOLOGÍA PARA EL DESARROLLLO

Santiago, Chile

Rodrigo Troncoso

Assistant professor

Universidad de Chile, Instituto de Nutrición y Tecnología de los Alimentos

Santiago de Chile, Chile

Carolina Ribeiro

Assistant Professor

Immunology Program

UNIVERSIDAD DE CHILE - FACULTAD DE MEDICINA

Santiago, Chile

Alejandro Escobar

assistant professor

Institute for Research in Dental Sciences

UNIVERSIDAD DE CHILE

Santiago, Chile

Maria Vega

Academico Profesora Titular

Obstetricia y Ginecologia Campus Norte

UNIVERSIDAD DE CHILE - FACULTAD DE MEDICINA

Santiago, Chile

GALIA RAMIREZ

PROFESOR ASISTENTE

DEPARTAMENTO DE MEDICINA PREVENTIVA ANIMAL

UNIVERSIDAD DE CHILE - FACULTAD DE CIENCIAS VETERINARIAS Y PECUARIAS

Santiago, Chile

Christopher Hamilton-West

Profesor Titular

FACULTAD DE CIENCIAS VETERINARIAS Y PECUARIAS, UNIVERSIDAD DE CHILE

Santiago, Chile

CAROLINA VALCK

ASSISTANT PROFESSOR

IMMUNOLOGY DISCIPLINARY PROGRAM

UNIVERSIDAD DE CHILE

Santiago, Chile

Jimena Cuenca

Investigador/profesor

Facultad de Medicina

Universidad de Los Andes

Santiago, Chile

LORENA AGUILAR

Assistant Professor

Animal Pathology

Faculty of Veterinary Medicine and Livestock Sciences, University of Chile

Santiago, Chile

Flavio Salazar

Profesor Titular

Oncología Básico Clínica

Universidad de Chile

SANTIAGO, Chile

146

ARTURO FERREIRA

FULL PROFESSOR, CHAIR IMMUNOLOGY DISCIPLINARY PROGRAM

IMMUNOLOGY

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

Ulrike Kemmerling

Full Professor

ICBM

Facultad de Medicina, Universidad de Chile

Santiago, Chile

Mercedes López

Profesora Asociada

Instituto de Ciencias Biomédicas

Universidad de chile

Santiago, Chile

Rodrigo Lopez

Profesor Asociado

Facultad de Ciencias Veterinarias

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

daniel hevia

Investigador PhD

Inmunologia

Universidad de Chile

santiago, Chile

Raquel Aguilera

PROFESOR ASISTENTE

INMUNOLOGÍA CLÍNICA Y REUMATOLOGÍA

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

Andrés Tittarelli

Profesor Asociado

Instituto Universitario de Investigación y Desarrollo Tecnológico (IDT)

Universidad Tecnológica Metropolitana

Santiago, Chile

Katherine Weinberger

Docente adjunto

Ciencias Morfologicas

Universidad San Sebastian

Santiago, Chile

Lorena Salazar

Academico

Instituto Cs Biomédicas

Universidad Autónoma de Chile

Santiago, Chile

Paula Abello

Docente Adjunto

Ciencias Biológicas

Universidad San Sebastián

Santiago, Chile

Ismael Maldonado

Asistente de Investigación

Inmunología

Universidad de Chile

Santiago, Chile

Rodrigo Troncoso

Associate Professor

Instituto de Nutrición y Tecnología de los Alimentos

Santiago, Chile

Dasfne Lee-Liu

Postdoctoral Researcher

Biology

Universidad de Chile

Santiago, Chile

CARLOS ROSAS

Profesor Asociado

Universidad San Sebastián

Valdivia, Chile

Fermín González

Profesor Asociado

Odontología Conservadora

Universidad de Chile

Santiago, Chile

Diego Catalán

Associate Professor

Programa Disciplinario de Inmunología

Universidad de Chile

Santiago, Chile

Karla Kohan

Profesional de laboratorio

Instituto de Salud Pública

Santiago, Chile

GLORIA TORRES

Investigadora Postdoctoral

CIIB

Universidad de Los Andes

Santiago, Chile

ARTURO .Luis FERREIRA VIGOUROUX

Líneas de Investigación

Educación

IMMUNOLOGY, UNIVERSIDAD DE CHILE. Chile, 1982

Veterinarian, UNIVERSIDAD DE CHILE. Chile, 1968

Experiencia Académica

Instructor Full Time

ASSISTANT PROFESSOR Full Time

ASSOCIATE RESEARCH SCIENTIST Full Time

RESEARCH SCIENTIST Full Time

ASSOCIATE PROFESSOR Full Time

ASSOCIATE PROFESSOR Full Time

FULL PROFESSOR Full Time

ASSOCIATE PROFESSOR Full Time

FULL PROFESSOR Full Time

Experiencia Profesional

Full Professor Full Time

Formación de Capital Humano

Difusión y Transferencia

Premios y Distinciones

President of Asociación Latinoamericana de Inmunología

Head of PhD Committee

Award for Excellent Academic

Vice President Superior Committee of Academic Evaluation

Research Director of Instituto de Ciencias Biomédicas

Honorary Visiting Professor

Vice-Dean

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