PDI - Resultado de Búsqueda

Diego Catalán Martina

Associate Professor

Universidad de Chile

Santiago, Chile

Linfocitos B reguladores en autoinmunidad Búsqueda de epitopos T inmunodominantes en artritis reumatoide

Licenciado en Medicina, UNIVERSIDAD DE CHILE. Chile, 2004
Ciencias Biomédicas, UNIVERSIDAD DE CHILE. Chile, 2010

Associate Professor Full Time

UNIVERSIDAD DE CHILE

Medicina

Santiago, Chile

2022 - A la fecha
Assistant Professor Full Time

UNIVERSIDAD DE CHILE

Facultad de Medicina

Santiago, Chile

2010 - 2022

Assistant Professor Full Time

Universidad de Chile

Chile

2010 - 2022
Associate Professor Full Time

Universidad de Chile

Santiago, Chile

2022 - A la fecha


B cell contribution to immunometabolic dysfunction and impaired immune responses in obesity Oleinika, Kristine; Slisere, Baiba; Catalan, Diego; Rosser, Elizabeth C. Article ISI CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2022)
Isolation of HLA-DR-naturally presented peptides identifies T-cell epitopes for rheumatoid arthritis Maggi, Jaxaira; Carrascal, Montserrat; Soto, Lilian; Neira, Oscar; Cuellar, Maria C.; Aravena, Octavio; James, Eddie A.; Abian, Joaquin; Jaraquemada, Dolores; Catalan, Diego; Aguillon, Juan C. Article ISI ANNALS OF THE RHEUMATIC DISEASES (2022)
Response to: Correspondence on "HLA-DR 'naturally' presented peptides: you will find what you have pulsed with" by Maggi et al Catalan, Diego; Jaraquemada, Dolores; Aguillon, Juan C. Article ISI ANNALS OF THE RHEUMATIC DISEASES (2022)
TNF-alpha Affects Signature Cytokines of Th1 and Th17 T Cell Subsets through Differential Actions on TNFR1 and TNFR2 Pesce, Barbara; Ribeiro, Carolina H.; Larrondo, Milton; Ramos, Veronica; Soto, Lilian; Catalan, Diego; Aguillon, Juan Carlos Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)
Immunosuppressive Mechanisms of Regulatory B Cells Catalan, Diego; Mansilla, Miguel Andres; Ferrier, Ashley; Soto, Lilian; Oleinika, Kristine; Aguillon, Juan Carlos; Aravena, Octavio Article ISI FRONTIERS IN IMMUNOLOGY (2021)
Microbiota-Derived Metabolites Suppress Arthritis by Amplifying Aryl-Hydrocarbon Receptor Activation in Regulatory B Cells Rosser E.C.; Piper C.J.M.; Matei D.E.; Blair P.A.; Rendeiro A.F.; Orford M.; Alber D.G.; Krausgruber T.; Catalan, D; Klein N.; Manson J.J.; Drozdov I.; Bock C.; Wedderburn L.R.; Eaton S.; Mauri C. Article SCOPUS CELL METABOLISM (2020)
Regulation of Tolerogenic Features on Dexamethasone-Modulated MPLA-Activated Dendritic Cells by MYC Garcia-Gonzalez, Paulina A.; Maggi, Jaxaira; Schinnerling, Katina; Sepulveda-Gutierrez, Alejandro; Soto, Lilian; Neire, Oscar; Mehdi, Ahmed M.; Nel, Hendrik J.; Pesce, Barbara; Aravena, Octavio; Carmen Molina, Maria; Catalan, Diego; Thomas, Ranjeny; Verdugo, Ricardo A.; Carlos Aguillon, Juan Article ISI SCOPUS FRONTIERS IN IMMUNOLOGY (2019)
Analysis of the HLA-DR peptidome from human dendritic cells reveals high affinity repertoires and nonconventional pathways of peptide generation Ciudad M.T.; Sorvillo N.; Van Alphen F.P.; Catalán D.; Meijer A.B.; Voorberg J.; Jaraquemada D. Article ISI SCOPUS JOURNAL OF LEUKOCYTE BIOLOGY (2017)
Dexamethasone and Monophosphoryl lipid a induce a Distinctive Profile on Monocyte-Derived Dendritic cells through Transcriptional Modulation of genes associated With essential Processes of the immune response Garcia-Gonzalez, PA; Schinnerling, K; Sepulveda-Gutierrez, A; Maggi, J; Mehdi, AM; Nel, HJ; Pesce, B; Larrondo, ML; Aravena, O; Molina, MC; Catalán, D; Thomas, R; Verdugo, RA; Aguillón, JC Article ISI SCOPUS Frontiers in immunology (2017)
STAT3 inhibition by STA21 increases cell surface expression of MICB and the release of soluble MICB by gastric adenocarcinoma cells Garrido-Tapia, Macarena; Hernández, Carolina J.; Ascui, Gabriel; Kramm, Karina; Morales, Marcela; Gárate, Valentina; Zúñiga, Roberto; Bustamante, Marco; Aguillón, Juan Carlos; Catalán, Diego; Ribeiro, Carolina H.; Molina, María Carmen Article ISI SCOPUS IMMUNOBIOLOGY (2017)
TIM-1 defines a human regulatory B cell population that is altered in frequency and function in systemic sclerosis patients Aravena O.; Ferrier A.; Menon M.; Mauri C.; Aguillón J.C.; Soto L.; Catalán D. Article ISI SCOPUS ARTHRITIS RESEARCH THERAPY (2017)
Clinical significance of tumor expression of major histocompatibility complex class I-related chains A and B (MICA/B) in gastric cancer patients Ribeiro, CH; Kramm, K.; Galvez-Jiron, F; Pola, V.; Bustamante, M; Contreras, HR; Sabag A.; Garrido-Tapia, M; Hernandez, CJ; Zúñiga R.; Collazo, N.; Sotelo, PH; Morales C. ; Mercado L.; Catalan, D; Aguillón JC; Molina, MC Article ISI SCOPUS ONCOLOGY REPORTS (2016)
Dexamethasone and Monophosphoryl Lipid A-Modulated Dendritic Cells Promote Antigen-Specific Tolerogenic Properties on Naive and Memory CD4(+) T cells Maggi, J; Schinnerling, K; Pesce, B; Hilkens, CM; Catalán, D; Aguillón, JC Article ISI SCOPUS FRONTIERS IN IMMUNOLOGY (2016)
Treatment with Dexamethasone and Monophosphoryl lipid a removes Disease-associated Transcriptional signatures in Monocyte-Derived Dendritic cells from rheumatoid arthritis Patients and confers Tolerogenic Features Garcia-Gonzalez, PA; Schinnerling, K; Sepulveda-Gutierrez, A; Maggi, J; Hoyos, L; Morales, RA; Mehdi, AM; Nel, HJ; Soto, L; Pesce, B; Molina, MC; Cuchacovich, M; Larrondo, ML; Neira, O; Catalan, DF; Hilkens, CM; Thomas, R; Verdugo, RA; Aguillón, JC Article ISI SCOPUS FRONTIERS IN IMMUNOLOGY (2016)
Neuropilin-1(+) regulatory T cells promote skin allograft survival and modulate effector CD4(+) T cells phenotypic signature Campos-Mora, M; Morales, R. A.; Pérez F.; Gajardo, T; Campos J.; Catalan, D; Aguillon, J.C.; Pino-Lagos, K Article ISI SCOPUS IMMUNOLOGY AND CELL BIOLOGY (2015)
Rapamycin-conditioned dendritic cells activated with monophosphoryl lipid A promote allograft acceptance in vivo Campos-Acuna, J; Pérez F.; Narvaez, E; Campos-Mora, M; Gajardo, T; Catalan, D; Aguillón JC; Pino-Lagos, K Article ISI SCOPUS Immunotherapy (2015)
Systemic sclerosis patients present alterations in the expression of molecules involved in B-cell regulation Soto L.; Ferrier, A; Aravena, O; Fonseca, E; Berendsen, J; Biere, A; Bueno, D.; Ramos, V; Aguillón JC; Catalan, D Article ISI SCOPUS Frontiers in immunology (2015)
Therapeutic potential of hyporesponsive CD4(+) T cells in autoimmunity Maggi, J; Schafer, C.; Ubilla-Olguin, G; Catalan, D; Schinnerling, K; Aguillón JC Article ISI SCOPUS Frontiers in immunology (2015)
Tolerogenic Dendritic Cells Derived from Donors with Natural Rubber Latex Allergy Modulate Allergen-Specific T-Cell Responses and IgE Production Escobar A.; Aguirre A.; Guzman, MA; González R.; Catalan, D; Acuna-Castillo, C; Larrondo M.; López MN; Pesce B,; Rolland J; Oâ€™hehir R.; Aguillón JC Article ISI SCOPUS PLOS ONE (2014)
A short protocol using dexamethasone and monophosphoryl lipid A generates tolerogenic dendritic cells that display a potent migratory capacity to lymphoid chemokines Garcia-Gonzalez, P; Morales R.; Hoyos L; Maggi, J; Campos J.; Pesce B,; Garate, D; Larrondo M.; González R.; Soto L.; Ramos, V; Tobar, P.; Molina, MC; Pino-Lagos, K; Catalan, D; Aguillón JC Article ISI SCOPUS Journal of Translational Medicine (2013)
Blocking of p38 and transforming growth factor ss receptor pathways impairs the ability of tolerogenic dendritic cells to suppress murine arthritis Garate, D; Rojas-Colonelli, N; Peña C; Salazar, L; Abello P; Pesce B,; Aravena, O; Garcia-Gonzalez, P; Ribeiro, CH; Molina, MC; Catalan, D; Aguillón JC Article ISI SCOPUS Arthritis and Rheumatism (2013)
Dexamethasone Preconditioning Improves the Response of Collagen-Induced Arthritis to Treatment with Short-Term Lipopolysaccharide-Stimulated Collagen-Loaded Dendritic Cells Peña C; Garate, D; Contreras-Levicoy, J; Aravena, O; Catalan, D; Aguillón JC Article ISI SCOPUS Clinical and Developmental Immunology (2013)
Effect of interleukin-6 receptor blockade on the balance between regulatory T cells and T helper type 17 cells in rheumatoid arthritis patients Pesce B,; Soto L.; Sabugo, F; Wurmann, P; Cuchacovich M.; López MN; Sotelo, PH; Molina, MC; Aguillón JC; Catalan, D Article ISI SCOPUS Clinical and Experimental Immunology (2013)
The immunological response and post-treatment survival of DC-vaccinated melanoma patients are associated with increased Th1/Th17 and reduced Th3 cytokine responses Duran-Aniotz, C; Segal G; Salazar, L; Pereda, C; Falcon, C; Tempio F.; Aguilera R.; González R.; Pérez, C.; Tittarelli, A; Catalan, D; Nervi, B; Larrondo M.; SALAZAR ONFRAY F; López MN Article ISI SCOPUS Cancer Immunology, Immunotherapy (2013)
An efficient method for variable region assembly in the construction of scFv phage display libraries using independent strand amplification Sotelo, P.H.; Collazo, N.; Zúñiga R.; Gutierrez-Gonzalez M.; Catalan, D; Ribeiro, C.H.; Aguillon, J.C.; Molina, M. C. Article ISI SCOPUS mAbs (2012)
Weak CD4+ T-cell responses to citrullinated vimentin in rheumatoid arthritis patients carrying HLA-DR9 alleles Catalan, D; Aravena, O; Zúñiga R.; Silva N.; Escobar A.; Sabugo, F; Wurmann, P; Soto L.; González R.; Alfaro, J; Larrondo M.; Cuchacovich M.; Aguillon, J.C. Article ISI SCOPUS Rheumatology International (2012)
Anti-TNF therapy in patients with rheumatoid arthritis decreases Th1 and Th17 cell populations and expands IFN-gamma-producing NK cell and regulatory T cell subsets Aravena, O; Pesce B,; Soto L.; Orrego, N.; Sabugo, F; Wurmann, P; Molina, MC; Alfaro, J; Cuchacovich M.; Aguillón JC; Catalan, D Article ISI SCOPUS Immunobiology (2011)
The presence of anti-citrullinated protein antibodies (ACPA) does not affect the clinical response to adalimumab in a group of RA patients with the tumor necrosis factor (TNF) alpha-308 G/G promoter polymorphism Soto L.; Sabugo, F; Catalan, D; Wurmann, P; Cermenatti T.; Gatica H.; Aravena, O; Salazar, L; Aguillón JC; Cuchacovich M. Article ISI SCOPUS Clinical Rheumatology (2011)
B cells from rheumatoid arthritis patients show important alterations in the expression of CD86 and Fc gamma RIIb, which are modulated by anti-tumor necrosis factor therapy Catalan, D; Aravena, O; Sabugo, F; Wurmann, P; Soto L.; Kalergis, AM; Cuchacovich M.; Aguillón JC Article ISI SCOPUS Arthritis Research and Therapy (2010)
Perfil de producción de citoquinas en linfocitos T de sangre periférica de pacientes con poliposis nasal y asma bronquial en respuesta a la estimulación con enterotoxina estafilocócica B Gormaz B, Juan Pablo; Gajardo 0, Pilar; Escobar A, Alejandro; Olavarría L, Christian; SCHÖNFFELDT G, PATRICIA; Sariego R, Homero; Catalán M, Diego; Aguillón G, Juan Carlos Article SCIELO REVISTA DE OTORRINOLARINGOLOGIA Y CIRUGIA DE CABEZA Y CUELLO (2010)
Basal anti-cyclic citrullinated peptide (anti-CCP) antibody levels and a decrease in anti-CCP titres are associated with clinical response to adalimumab in rheumatoid arthritis Cuchacovich M.; Catalan, D; Wainstein E.; Gatica H.; Soto L.; Aravena, O; Pesce B,; Sabugo, F; Aguillón JC Article ISI SCOPUS CLINICAL AND EXPERIMENTAL RHEUMATOLOGY (2008)
Modulation of established murine collagen-induced arthritis by a single inoculation of short-term lipopolysaccharide-stimulated dendritic cells Salazar, L; Aravena, O; Abello P; Escobar A.; Contreras-Levicoy, J; Rojas-Colonelli, N; Catalan, D; Aguirre A.; Zúñiga R.; Pesce B,; González C; Cepeda R.; Cuchacovich M.; Molina, MC; SALAZAR ONFRAY F; Delgado M.; Toes, RE; Aguillón JC Article ISI SCOPUS ANNALS OF THE RHEUMATIC DISEASES (2008)
Inflammation, synovial angiogenesis and chondroid apoptosis in the evolution of type II collagen-induced arthritis González C; Abello P; Cepeda R.; Salazar, L; Aravena, O; Pesce B,; Catalan, D; Aguillón JC Article ISI SCOPUS European Cytokine Network (2007)
Short-term lipopolysaccharide stimulation indeces differentiation of murine bone marrow-derived dentritic cells into tolerogenic phenotype Salazar, L; Aravena, O; Contreras-Levicoy, J; Pesce B,; Catalan, D; Zúñiga R.; Iruretagoyena M.; Kalergis, AM; Aguillón JC Article ISI SCOPUS European Cytokine Network (2007)
Tumour necrosis factor (TNF)alpha-308 G/G promoter polymorphism and TNF alpha levels correlate with a better response to adalimumab in patients with rheumatoid arthritis Cuchacovich M.; Soto L.; Edwardes, M; Gutiérrez M; Llanos, C.; Pacheco, D.; Sabugo, F; Alamo, M; Fuentealba, C; Villanueva, L; Gatica H.; Schiattino, I; Salazar, L; Catalan, D; Valenzuela O. Article ISI SCOPUS SCANDINAVIAN JOURNAL OF RHEUMATOLOGY (2006)
Multiple imputation procedures allow the rescue of missing data: An application to determine serum tumor necrosis factor (TNF) concentration values during the treatment of rheumatoid arthritis patients with anti-TNF therapy Schiattino, I; Villegas, R; Cruzat, A; Cuenca J.; Salazar, L; Aravena, O; Pesce B,; Catalan, D; Llanos, C.; Cuchacovich M.; Aguillón JC Article ISI SCIELO SCOPUS Biological Research (2005)
The -308 polymorphism in the promoter region of the tumor necrosis factor-alpha (TNF-?) gene and ex vivo lipopolysaccharide-induced TNF-? expression in patients with aggressive periodontitis and/or type 1 diabetes mellitus Pérez, C.; González F.E.; Aguirre A.; Cruzat, A; Contreras-Levicoy, J; Dotte, A; Aravena, O; Salazar, L; Catalan, D; Cuenca J.; Ferreira A.; Aguillon, J.C.; Pavez, V; Araya A.V.; Schiattino, I Article SCOPUS European Cytokine Network (2004)
The -308 polymorphism in the promotor region of the tumor necrosis factor-alpha (TNF-alpha) gene and ex vivo lipopolysaccharide-induced TNF-alpha expression in patients with aggresive peridontitis and/or type 1 diabetes mellitus Pérez, C.; Gonzalez, FE; Pavez, V; Araya, AV; Aguirre A.; Cruzat, A; Contreras-Levicoy, J; Dotte, A; Aravena, O; Salazar, L; Catalan, D; Cuenca J.; Ferreira A.; Schiattino, I; Aguillón JC Article ISI European Cytokine Network (2004)
Nuevas armas inmunológicas para la medicina del siglo XXI: Terapia biológica basada en el uso de anticuerpos monoclonales de última generación Aguillón G, Juan C; Contreras L, Juan; Dotte G, Andrés; Cruzat C, Andrea; Catalán M, Diego; Salazar A, Lorena; Molina S, María Carmen; Guerrero P, Julia; López N, Mercedes; Soto S, Lilian; Salazar-Onfray, Flavio; Cuchacovich T, Miguel Article SCIELO REVISTA MEDICA DE CHILE (2003)


Identification of T-cell autoantigenic peptides in rheumatoid arthritis as new targets for an antigen-specific dendritic cell-based therapy Maggi, J; Aravena, O; Catalan, D; Schinnerling, K; Soto, L; Neira, O; Cuellar, MC; Carrascal, M; Jaraquemada, D; Aguillon, JC Abstract ISI EUROPEAN JOURNAL OF IMMUNOLOGY (2019)
Dexamethasone and MPLA treatment of monocyte-derived dendritic cells from rheumatoid arthritis patients induce transcriptional modulation of genes related to cell recruitment, signaling and metabolism Garcia-Gonzalez, PA; Schinnerling, K; Sepulveda, A; Ubilla-Olguin, G; Soto, L; Neira, O; Medhi, AM; Nel, HJ; Catalán, D; Thomas, R; Verdugo, RA; Aguillón, JC Abstract ISI (2016)
Treatment with Dexamethasone and Monophosphoryl Lipid a Removes Disease-Associated Transcriptional Signatures in Monocyte-Derived Dendritic Cells from Rheumatoid Arthritis Patients and Confers the Ability to Modulate CD4+T Cell Responses Garcia-Gonzalez, P; Neira, O; Schinnerling, K; Sepulveda-Gutierrez, A; Maggy, J; Hoyos, L; Morales, R; Ubilla-Olguin, G; Mehdi, A; Nel, H; Soto, L; Pesce, B; Molina, MC; Cuchacovich, M; Larrondo, M; Catalán, D; Hilkens, CM; Thomas, R; Verdugo, R; Aguillón, JC Abstract ISI (2016)
Adalimumab, a Tumor Necrosis Factor Blockade Therapy, Decreases Th1 and Th17 Populations in Rheumatoid Arthritis Patients Pesce B,; Catalan, D; Orrego, N.; Aravena, O; Soto L.; Wurman, P; Sabugo, F; Cuchacovich M.; Aguillon, J. Abstract ISI CLINICAL IMMUNOLOGY (2010)
Dexamethasone Pretreatment Followed by an Inoculation of Short-term Lipopolysaccharide-stimulated Dendritic Cells Improves the Response of Murine Collagen-induced Arthritis Aguillon, J.; Pena M.; Catalan, D; Aravena, O; Rojas-Colonelli, N; Garate, D Abstract ISI CLINICAL IMMUNOLOGY (2010)
Basal anti-cyclic citrullinated peptide (anti-ccp) antibodies levels and a decrease in anti-CCP titres are associated with clinical response to adalimumab therapy in rheumatoid arthritis patients Cuchacovich M.; Catalan, D; Wainstein E.; Gatica H.; Soto L.; Aravena, O; Pesce B,; Sabugo, F; Aguillon, J. Abstract ISI ANNALS OF THE RHEUMATIC DISEASES (2007)
Tumor necrosis factor-alpha levels gurrelate with a better response to adalimumab in patients with rheumatoid arthritis Cuchacovich M.; Soto L.; Gutiérrez M; Llanos, C.; Sabugo, F; Pacheco, D.; Alamos, M.; Fuentealba, C; Villanueva, L; Gatica H.; Schiattino, I; Salazar, L; Catalan, D; Valenzuela O.; SALAZAR ONFRAY F; Aguillon, J. Abstract ISI ANNALS OF THE RHEUMATIC DISEASES (2006)
Dendritic cells pulsed with type II bovine collagen modulate the murine collagen induced arthritis. Salazar, LE; Aravena, OA; Abello P; Aguirre A.; Catalan, D; Llanos, C.; Sabugo, F; González F; González C; Cuchacovich M.; Aguillón JC Abstract ISI CLINICAL IMMUNOLOGY (2005)
Ex vivo pro-inflammatory cytokines expression in patients with aggressive periodontitis. Gonzalez, FE; Catalan, D; Aguillón JC Abstract ISI CLINICAL IMMUNOLOGY (2005)
Rapid protocol to generate tolerogenic dendritic cells using microbial lipopeptide (BLP). Aravena, OA; Salazar, L; Mass, C; Aguirre A.; Catalan, D; Hermoso, M; Aguillón JC Abstract ISI CLINICAL IMMUNOLOGY (2005)
Tumor necrosis factor-alpha-308 G/G promoter polymorphism correlates with a better response to adalimumab in patients with rheumatoid arthritis. Cuchacovich M.; Soto L.; Edwardes, M; Gutiérrez M; Llanos, C.; Pacheco, D.; Sabugo, F; Alamo, M; Fuentealba, C; Villanueva, L; Gatica H.; Schiattino, I; Salazar, L; Catalan, D; Valenzuela O.; SALAZAR ONFRAY F; Aguillón JC Abstract ISI ARTHRITIS AND RHEUMATISM (2005)


Terapias emergentes en artritis reumatoide Aguillón G, Juan C; Cruzat C, Andrea; Contreras-Levicoy, Juan; Dotte G, Andrés; Pesce R, Bárbara; Aravena M, Octavio; Salazar A, Lorena; Catalán M, Diego; Abello C, Paula; Aguirre D, Adam; Llanos M, Carolina; Cuchacovich T, Miguel Actualizacion SCIELO REVISTA MEDICA DE CHILE (2005)


How we can improve the predictive value of prognostic biomarkers in rheumatoid arthritis Soto L.; Catalan, D; Aguillon, J.C.; Cuchacovich M. Editorial SCOPUS International Journal of Clinical Rheumatology (2015)


Editorial: Searching for immune tolerance Manipulating New Molecules and Exploiting New Concepts on lymphocyte Biology Catalan, D; Pino-Lagos, K EditorialMaterial ISI SCOPUS FRONTIERS IN IMMUNOLOGY (2016)


Perfil de sialilación en linfocitos T CD4+ como factor de resistencia a la supresión por linfocitos B reguladores Siglec-5hi en artritis reumatoide Catalán, Diego Proyecto (2022)
Plataforma de área limpia y equipamiento para la producción de prototipos basados en proteínas recombinantes, productos celulares y farmacéuticos estériles bajo buenas prácticas de manufactura para investigación en seres humanos Molina, María Carmen; Catalán, Diego; Aguillón, Juan Carlos; Altamirano, Claudia; HERMOSO MARCELA; CarreÑo, Leandro Javier; Sánchez, Gina; Rodrigo, Ramón; Naves, Rodrigo Proyecto (2022)
Unveiling naturally presented epitopes targeted by CD8+ T cells from rheumatoid arthritis patients: One step forward to understand the immunopathogenesis of the disease Aguillón, Juan Carlos; Catalán, Diego; Soto, Lilian; Neira, Oscar; Maggi, Jaxaira Proyecto (2022)
Understanding the influence of the inflamed synovial environment on Siglec-5-expressing regulatory B cells in rheumatoid arthritis patients Catalán, Diego Proyecto (2021)
Dissecting the interplay between commensal microbiota and regulatory B cells in SLE Catalán, Diego Proyecto (2018)
Exploring the interplay between gut flora and immune system in rheumatologic patients from Chile and UK Catalán, Diego Proyecto (2018)
Identifying immunodominant T–cell antigen–peptides and T–cell responses in rheumatoid arthritis: A further step in the development of an antigen–specific dendritic cell–based therapy to restore self–tolerance Aguillón, Juan Carlos; Catalan, Diego; Soto, Lilian; Neira, Oscar Proyecto (2018)
International research network on characterization of new therapeutic targets for rheumatoid arthritis Aguillón, Juan Carlos; Catalan, Diego; Thomas, Ranjeny; Jaraquemada, Dolores; Mauri, Claudia Proyecto (2018)
Pre-clinical evaluation and registration of tolerogenic dendritic cells pulsed with autoantigenic peptides (TOLDeC-AP) for antigen-specific immunotherapy of rheumatoid arthritis Aguillón, Juan Carlos; Soto, Lilian; Aravena, Octavio; Schinnerling, Katina Proyecto (2018)
Determinación del efecto de unidades de concentrados plaquetarios obtenidos de donantes de sangre sobre la modulación de linfocitos T alogénicos Dirección de Investigación y Tecnología, Facultad de Medicina, Universidad de Chile (000) Proyecto 2016-2016 Coinvestigador(a)
Instituto Milenio en Inmunología e Inmunoterapia, segunda etapa Iniciativa Científica Milenio (P09/016-F) Proyecto 2016-2021 Investigador(a)
Citómetro de Flujo Multiparamétrico FONDEQUIP (EQM140032) Proyecto 2015-2016 Investigador(a)
Development of an international research network focused on uncovering new molecular targets and evaluating novel cell-based strategies for the therapy of autoimmune diseases PCI (140041) Proyecto 2015-2016 Inv. Responsable
Indagando mecanismos inflamatorios y su relación con el stress oxidativo en pacientes con fibromialgia Hospital Clínico Universidad de Chile Proyecto 2015-2016 Coinvestigador(a)
Péptidos autoantigénicos presentados por células dendríticas tolerogénicas=> una terapia personalizada para reinstruir el sistema inmune de pacientes con artritis reumatoide FONDEF (ID15I10080) Proyecto 2015-2017 Subdirector(a)
SEARCHING FOR A VALIDATED CELL-BASED THERAPEUTIC APPROACH FOR THE TREATMENT OF RHEUMATOID ARTHRITIS=>IDENTITIFICATION OF SPECIFIC TOLERANCE MARKERS AND CHARACTERIZATION OF MONOPHOSPHORYL FONDECYT (1140553) Proyecto 2014-2018 Coinvestigador(a)
"Desarrollo, producción y caracterización de anticuerpos recombinantes de origen humano anti MICA con potencial terapéutico para el tratamiento de cáncer gástrico" FONDEF (CA12I10023) Proyecto 2013-2015 Investigador(a)
FCGAMMA RECEPTORS AND REGULATORY B CELLS=> A NOVEL NETWORK BEHIND THE IMMUNE RESPONSE GOVERNING SYSTEMIC SCLEROSIS FONDECYT (1121100) Proyecto 2012-2015 Coinvestigador(a)
SEEKING FOR MECHANISMS INVOLVED IN THE IL-10 SECRETION BY REGULATORY B CELLS=> IMPLICATIONS FOR THERAPEUTIC INTERVENTIONS ON AUTOIMMUNE DISEASES. FONDECYT (11121497) Proyecto 2012-2015 Inv. Responsable
EFECTOS DE LA TERAPIA CON UN ANTICUERPO CONTRA EL RECEPTOR DE IL-6 SOBRE LAS POBLACIONES LINFOCITARIAS Th17 Y Treg EN PACIENTES CON ARTRITIS REUMATOIDE Hospital Clínico, Universidad de Chile (450-10) Proyecto 2011-2012 Coinvestigador(a)
IDENTIFICACIÓN DE EPITOPOS T INMUNODOMINANTES EN ARTRITIS REUMATOIDE=> BUSCANDO LOS CANDIDATOS PARA EL DISEÑO DE UNA TERAPIA ANTÍGENO-ESPECÍFICA Vicerrectoría de Investigación Universidad de Chile (I 10/02-2) Proyecto 2011-2013 Inv. Responsable
APPLYING THE KNOWLEDGE ON MURINE TOLEROGENIC DENDRITIC CELLS TO THE DEVELOPMENT OF TOLEROGENIC MONOCYTE-DERIVED DENDRITIC CELLS FROM RHEUMATOID ARTHRITIS (RA) PATIENTS AIMED AT PROVIDING A THERAPEUTIC STRATEGY FOR RA TREATMENT FONDECYT (1100102) Proyecto 2010-2014 Coinvestigador(a)
DESARROLLO DE UN SISTEMA DE EXPRESIÓN OPTIMIZADO PARA LA PRODUCCIÓN DE ANTICUERPOS TERAPÉUTICOS FONDEF (D09I1190) Proyecto 2010-2014 Investigador(a)
INSTITUTO MILENIO EN INMUNOLOGÍA E INMUNOTERAPIA Iniciativa Científica Milenio (P09/016-F) Proyecto 2010-2015 Investigador(a)
EL FACTOR DE NECROSIS TUMORAL (TNF) EN EL BALANCE DE LOS EJES TH1/TH17=> LECCIONES DESDE LA TERAPIA ANTI-TNF EN ARTRITIS REUMATOIDE FONDECYT (1090174) Proyecto 2009-2012 Coinvestigador(a)


The role of interleukin-6 signalling and its therapeutic blockage in skewing the T cell balance in rheumatoid arthritis Schinnerling K.; Aguillón J.C.; Catalán D.; Soto L. Review ISI SCOPUS CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2017)
Tolerogenic dendritic cells for reprogramming of lymphocyte responses in autoimmune diseases Garcia-Gonzalez, P; Ubilla-Olguin, G; Catalán, D; Schinnerling, K; Aguillón, JC Review ISI SCOPUS AUTOIMMUNITY REVIEWS (2016)
Skewing dendritic cell differentiation towards a tolerogenic state for recovery of tolerance in rheumatoid arthritis Schinnerling, K; Soto L.; Garcia-Gonzalez, P; Catalan, D; Aguillón JC Review ISI SCOPUS Autoimmunity Reviews (2015)
Clinical parameters and biomarkers for anti-TNF treatment prognosis in rheumatoid arthritis patients Cuchacovich M.; Bueno, D.; Carvajal R.; Bravo N.; Aguillón JC; Catalan, D; Soto L. Review ISI SCOPUS CLINICAL RHEUMATOLOGY (2014)
Neuropilin-1 in transplantation tolerance Campos-Mora, M; Morales, RA; Gajardo, T; Catalan, D; Pino-Lagos, K Review ISI SCOPUS Frontiers in immunology (2013)
Emergent therapies for rheumatoid arthritis Aguillón JC; Cruzat, A; Contreras-Levicoy, J; Dotte, A; Pesce B,; Aravena, O; Salazar, L; Catalan, D; Abello P; Aguirre A.; Llanos, C.; Cuchacovich M. Review ISI REVISTA MEDICA DE CHILE (2005)
Biological therapy based on the use of last generation monoclonal antibodies Aguillón JC; Contreras, J.; Dotte, A; Cruzat, A; Catalan, D; Salazar, L; Molina, MC; Guerrero, J; Lopez M.; Soto L.; SALAZAR ONFRAY F; Cuchacovich M. Review ISI REVISTA MEDICA DE CHILE (2003)

Diego Catalán

Associate Professor

Programa Disciplinario de Inmunología

Universidad de Chile

Santiago, Chile

JUAN AGUILLON

PROFESSOR

IMMUNOLOGY PROGRAM

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

OCTAVIO ARAVENA

Director Científico

I+D+i

MEDICEL SA

Santiago, Chile

Lilian Soto

Rheumatologist

Medicine

CLINICAL HOSPITAL OF UNIVERSIDAD DE CHILE

Santiago, Chile

Bárbara Pesce

Profesora Asistente

ICBM

Universidad de Chile

Santiago, Chile

Lorena Salazar

Profesora Asistente

Instituto de Ciencias Biomédicas

Universidad Autónoma de Chile

Lampa, Chile

MARIA MOLINA

Director

Instituto de Ciencias Biomédicas

Universidad de Chile

INDEPENDENCIA, Chile

Lorena Salazar

Academico

Instituto Cs Biomédicas

Universidad Autónoma de Chile

Santiago, Chile

Katina Schinnerling

Profesor Asistente

Departamento de Ciencias Biológicas

Universidad Andrés Bello

Santiago, Chile

Maria Sabugo

Medico Reumatologo

Medicina

UNIVERSIDAD DE CHILE HOSPITAL CLÍNICO

Santiago, Chile

Roberto Zúñiga

Investigador Asociado a Proyectos

Programa Disciplinario de Inmunologia

Universidad de Chile/ Facultad de Medicina

Santiago, Chile

Carolina Llanos

Associate Professor

Pontificia Universidad Católica de Chile

Santiago, Chile

Paula Abello

Pamela Wurmann

reumatologa

medicina

universidad de chile

santiago, Chile

Karina Pino

Group Leader/Associate Professor

Centro de Investigación Biomédica

Universidad de los Andes

Santiago, Chile

Rodrigo Morales

Postdoctoral researcher

Dept. of Medicine Solna (MedS)

Karolinska Institutet

Stockholm, Suecia

Paulina García

Investigador Postdoctoral

Programa de Inmunologia

Universidad de Chile

Santiago, Chile

Ricardo Verdugo

Asistant Professor

Facultad de Medicina

UNIVERSIDAD DE CHILE

Santiago, Chile

Alejandro Escobar

assistant professor

Institute for Research in Dental Sciences

UNIVERSIDAD DE CHILE

Santiago, Chile

Mauricio Campos Mora

Ph.D student

Universidad de Chile

Santiago, Chile

Mercedes López

Profesora Asociada

Instituto de Ciencias Biomédicas

Universidad de chile

Santiago, Chile

Norberto Collazo

Business Developer

Center for Sustainable Biotechnology

Fraunhofer Chile Research

Santiago, Chile

Jimena Cuenca

Investigador/profesor

Facultad de Medicina

Universidad de Los Andes

Santiago, Chile

Veronica Ramos

Bioquímico

Inmunologia, VIH y Alergias

Hospital Clínico Universidad de Chile

Santiago, Chile

Fermín González

Profesor Asociado

Odontología Conservadora

Universidad de Chile

Santiago, Chile

Daniel Bueno

Médico

Servicio de Salud metropolitano Sur

Santiago, Chile

Marcela Hermoso

Full Professor

School of Medicine

UNIVERSIDAD DE CHILE

Santiago, Chile

Cristian Falcón

Urólogo

Hospital San Juan de Dios

Santiago, Chile

Fabian Tempio

Asistente de Investigación

Instituto de Ciencias Biomédicas

Universidad de Chile

Santiago, Chile

Andrés Tittarelli

Investigador

Universidad Tecnológica Metropolitana

Santiago, Chile

Julia Guerrero

académico

Programa Disciplinario Fisiologia y Biofisica

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

Hector Contreras

Academico

Oncologia Basico Clinica

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA, INSTITUTO DE CIENCIAS BIOMÉDICAS, PROGRAMA DE FISIOLOGÍA Y BIOFÍSICA

Santiago, Chile

ARTURO FERREIRA

FULL PROFESSOR, CHAIR IMMUNOLOGY DISCIPLINARY PROGRAM

IMMUNOLOGY

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

Matias Gutiérrez

Investigador

Programa Disciplinario de Inmunología

Universidad de Chile

Santiago, Chile

Bruno Nervi

Associated Professor

Hematology - Oncology

Pontificia Universidad Catolica de Chile

Santiago, Chile

Mirentxu Iruretagoyena

Jefe Seccion Inmunologia

Laboratorio Clinico

Clinica Alemana de Santiago

Santiago, Chile

Carolina Ribeiro

Assistant Professor

Immunology Program

UNIVERSIDAD DE CHILE - FACULTAD DE MEDICINA

Santiago, Chile

Alexis Kalergis

Full Professor

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE. FACULTAD DE CIENCIAS BIOLÓGICAS

Santiago, Chile

Flavio Salazar

Profesor titular

Instituto de ciencias biomédicas

Universidad de Chile

SANTIAGO, Chile

Raquel Aguilera

PROFESOR ASISTENTE

INMUNOLOGÍA CLÍNICA Y REUMATOLOGÍA

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

Rodrigo Villegas

Jefe Programa de Bioestadística

Bioestadística

Universidad de Chile - Facultad de Medicina

Santiago, Chile

Luis Mercado

Profesor Titular

Instituto de Biología

Pontificia Universidad Católica de Valparaíso

Valparaíso, Chile

Claudio Acuña

Profesosr Asociado

Biología

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

Diego Catalán Martina

Líneas de Investigación

Educación

Licenciado en Medicina, UNIVERSIDAD DE CHILE. Chile, 2004

Ciencias Biomédicas, UNIVERSIDAD DE CHILE. Chile, 2010

Experiencia Académica

Associate Professor Full Time

Assistant Professor Full Time

Experiencia Profesional

Assistant Professor Full Time

Associate Professor Full Time

Article (39)

Abstract (11)

Actualizacion (1)

Editorial (1)

EditorialMaterial (1)

Proyecto (25)

Determinación del efecto de unidades de concentrados plaquetarios obtenidos de donantes de sangre sobre la modulación de linfocitos T alogénicos

Instituto Milenio en Inmunología e Inmunoterapia, segunda etapa

Citómetro de Flujo Multiparamétrico

Development of an international research network focused on uncovering new molecular targets and evaluating novel cell-based strategies for the therapy of autoimmune diseases

Indagando mecanismos inflamatorios y su relación con el stress oxidativo en pacientes con fibromialgia

Péptidos autoantigénicos presentados por células dendríticas tolerogénicas=> una terapia personalizada para reinstruir el sistema inmune de pacientes con artritis reumatoide

SEARCHING FOR A VALIDATED CELL-BASED THERAPEUTIC APPROACH FOR THE TREATMENT OF RHEUMATOID ARTHRITIS=>IDENTITIFICATION OF SPECIFIC TOLERANCE MARKERS AND CHARACTERIZATION OF MONOPHOSPHORYL

"Desarrollo, producción y caracterización de anticuerpos recombinantes de origen humano anti MICA con potencial terapéutico para el tratamiento de cáncer gástrico"

FCGAMMA RECEPTORS AND REGULATORY B CELLS=> A NOVEL NETWORK BEHIND THE IMMUNE RESPONSE GOVERNING SYSTEMIC SCLEROSIS

SEEKING FOR MECHANISMS INVOLVED IN THE IL-10 SECRETION BY REGULATORY B CELLS=> IMPLICATIONS FOR THERAPEUTIC INTERVENTIONS ON AUTOIMMUNE DISEASES.

EFECTOS DE LA TERAPIA CON UN ANTICUERPO CONTRA EL RECEPTOR DE IL-6 SOBRE LAS POBLACIONES LINFOCITARIAS Th17 Y Treg EN PACIENTES CON ARTRITIS REUMATOIDE

IDENTIFICACIÓN DE EPITOPOS T INMUNODOMINANTES EN ARTRITIS REUMATOIDE=> BUSCANDO LOS CANDIDATOS PARA EL DISEÑO DE UNA TERAPIA ANTÍGENO-ESPECÍFICA

APPLYING THE KNOWLEDGE ON MURINE TOLEROGENIC DENDRITIC CELLS TO THE DEVELOPMENT OF TOLEROGENIC MONOCYTE-DERIVED DENDRITIC CELLS FROM RHEUMATOID ARTHRITIS (RA) PATIENTS AIMED AT PROVIDING A THERAPEUTIC STRATEGY FOR RA TREATMENT

DESARROLLO DE UN SISTEMA DE EXPRESIÓN OPTIMIZADO PARA LA PRODUCCIÓN DE ANTICUERPOS TERAPÉUTICOS

INSTITUTO MILENIO EN INMUNOLOGÍA E INMUNOTERAPIA

EL FACTOR DE NECROSIS TUMORAL (TNF) EN EL BALANCE DE LOS EJES TH1/TH17=> LECCIONES DESDE LA TERAPIA ANTI-TNF EN ARTRITIS REUMATOIDE

Review (7)