Man

Rodrigo Luis Villegas Ríos

Jefe Programa de Bioestadística

Universidad de Chile - Facultad de Medicina

Santiago, Chile

Líneas de Investigación


Métodología estadística aplicada en estudios epidemiológicos observacionales relacionados con factores ambientales y estilos de vida; Modelos Lineales; Estadística Computacional.

Educación

  •  Estadística, Universidad de Barcelona. España, 2015
  •  Bioestadística, UNIVERSIDAD DE CHILE. Chile, 1998
  •  Estadístico, UNIVERSIDAD DE VALPARAISO. Chile, 1992

Experiencia Académica

  •   Jefe Departamento Full Time

    UNIVERSIDAD DE CHILE

    Medicina

    Santiago, Chile

    2018 - A la fecha

  •   Académico Full Time

    UNIVERSIDAD DE CHILE

    Medicina

    Santiago, Chile

    1998 - 2011

Experiencia Profesional

  •   Bioestadístico Full Time

    Instituto de Salud Pública de Chile

    Santiago, Chile

    2014 - 2017

Premios y Distinciones

  •   Alice Hamilton Science Award 2012

    National Institute for Occupational Safety and Health

    Estados Unidos, 2012

    1) Honorable Mention (Jointly submitted): Title: Risk of brain tumours in relation to estimated RF dose from mobile phones: results from five Interphone countries Authors: Cardis E, Armstrong BK, Bowman JD, Giles GG, Hours M, Krewski D, McBride M, Parent ME, Sadetzki S, Woodward A, Brown J, Chetrit A, Figuerola J, Hoffmann C, Jarus-Hakak A, Montestruq L, Nadon L, Richardson L, Villegas R, Vrijheid M Source: Occup Environ Med 68(9):631-640, 2011 2) Title: Estimation of RF energy absorbed in the brain from mobile phones in the Interphone Study Authors: Cardis E, Varsier N, Bowman JD, Deltour I, Figuerola J, Mann S, Moissonnier M, Taki M, Vecchia P, Villegas R, Vrijheid M, Wake K, Wiart J Source: Occup Environ Med 68(9):686-693, 2011 Description: These two papers are a dramatic demonstration of an epidemiologic study which was improved by incorporating biophysical principles and additional data into the exposure assessment. A 13-nation Interphone Study of cell phones and brain cancer had originally reported a puzzling U-shaped dose-response of the risks related to the time of cell phone use reported at interviews. Since the radio-frequency (RF) energy absorbed in the brain is determined by many factors beyond cell phone usage time, a novel biophysical model was developed of the RF dose at the tumour site from the cell phones used by the Interphone subjects. This model incorporated all the cell phone types mentioned during the subject interviews, laboratory dosimetry data on these cell phones, present-day measurements of a phone’s average output power in the subject’s cellular network, and the tumour’s coordinates from radiologists. The model then calculated the cumulative specific RF energy absorbed at the tumour’s center. When this RF dose model was used to reanalyze the brain cancer risks with data from 5 of the 13 Interphone countries, a significant dose-response was found with gliomas for phone use of more than 7 years. This outcome would be expected if the probability of tumorigenesis progressing through one or more stages was proportional to the RF power absorbed by a glia cell. Confirming a biologically-based hypothesis with a well-designed epidemiologic study provided some evidence that the RF emissions from cell phones could be a causal factor in brain cancer. A recent working group of the International Agency for Research on Cancer (IARC) found RF electromagnetic fields, including radiation from cell phones, to be a possible human carcinogen. In justifying this decision, IARC’s summary report cited the Risk paper’s dose-response from more than 7 years of phone use. In addition to providing evidence for cell phone carcinogenesis, the findings of these two papers also help identify preventive measures. Effective preventions would include reducing the time talking on the phone and the amount of RF radiation reaching the head by using hands-free devices, the speaker-phone mode, or text messaging.


 

Article (38)

First inter-laboratory comparison of Echinococcus granulosus sensu lato diagnosis in Latin America
What is the effect of a Mediterranean compared with a Fast Food meal on the exercise induced adipokine changes? A randomized cross-over clinical trial
Effectiveness of sampling methods employed for Acanthamoeba keratitis diagnosis by culture
Gasto de Bolsillo en Salud y Medicamentos en Chile: Análisis Comparativo de los Periodos 1997, 2007, y 2012
Meal-exercise challenge and physical activity reduction impact on immunity and inflammation (MERIIT trial)
The Optimisation of the Expression of Recombinant Surface Immunogenic Protein of Group B Streptococcus in Escherichia coli by Response Surface Methodology Improves Humoral Immunity
Diet and Respiratory Health in Children from 11 Latin American Countries: Evidence from ISAAC Phase III
Dietary intake of carbohydrates, daytime sleepiness and obstructive sleep apnoea in adults from reykjavík, Iceland
Exposición a polvo de harina de trigo en panaderías de la Región Metropolitana
Investigation of bias related to differences between case and control interview dates in five INTERPHONE countries
Investigation of bias related to differences between case and control interview dates in five INTERPHONE countries
Empirical study of correlated survival times for recurrent events with proportional hazards margins and the effect of correlation and censoring
Empirical study of correlated survival times for recurrent events with proportional hazards margins and the effect of correlation and censoring
Estimation of RF energy absorbed in the brain from mobile phones in the Interphone Study
Estimation of RF energy absorbed in the brain from mobile phones in the Interphone Study
Risk of brain tumours in relation to estimated RF dose from mobile phones=> results from five Interphone countries.
Risk of brain tumours in relation to estimated RF dose from mobile phones: results from five Interphone countries
Determinants of oral contraception use in a southern European setting
Determinants of oral contraception use in a southern European setting.
Perceived discrimination and health by gender, social class, and country of birth in a Southern European country
Changes in the population smoking patterns: Barcelona, 1983-2006
Effect of Dietary Intake on the Levels of Biliary Unsaturated Free Fatty Acids Having Inhibitory Activity on Mutagens
Understanding the relationship of long working hours with health status and health-related behaviours
Immunogenicity of a 23-valent pneumococcal polysaccharide vaccine in elderly residents of a long-term care facility
Free fatty acid concentrations in gallbladder bile collected from Chilean patients with gallstones
Tendencia de la mortalidad por tumores cerebrales malignos en Chile: Análisis de tasas
Comparison of cyclosporine concentrations 2 hours post-dose determined using 3 different methods and trough level in pediatric renal transplantation
Multiple imputation procedures allow the rescue of missing data: An application to determine serum tumor necrosis factor (TNF) concentration values during the treatment of rheumatoid arthritis patients with anti-TNF therapy
Pediatric renal transplantation: 13 years of experience - Report from the Chilean cooperative multicenter group
Prevalence of latex hypersensitivity in operating room workers of the University of Chile Clinical Hospital
Prevalence of latex hypersensitivity in operating room workers of the University of Chile Clinical Hospital [Prevalencia de sensibilización a látex en personal de pabellones quirúrgicos del Hospital Clínico de la Universidad de Chile]
Prevalence of latex hypersensitivity in operating room workers of the University of Chile Clinical Hospital [Prevalencia de sensibilización a látex en personal de pabellones quirúrgicos del Hospital Clínico de la Universidad de Chile]
Short-term homeostasis of REM sleep throughout a 12 : 12 Light : Dark schedule in the rat
Fine particulate matter and wheezing illnesses in the first year of life
A semi-quantitative method to assess oral infections with Streptococci mutans in preschool Chilean children
Quantitative relationship between salivary level of Streptococcus mutans and Candida albicans in children with Down's syndrome Relación cuantitativa entre el nivel de Streptococcus mutans y Candida albicans en niños con síndrome de Down
Vertical dimension. Part 1: Comparison of clinical freeway space
Effects of head and neck inclination on bilateral sternocleidomastoid EMG activity in healthy subjects and in patients with myogenic cranio-cervical-mandibular dysfunction

Abstract (4)

Dialysis dose and nutritional parameters in chronic pediatric peritoneal dialysis
Association between Canes experience and S. mutans level in saliva in a group of preschool Chilean children.
First and subsequent episodes of wheezing bronchitis from birth to 12 months: A follow up study
S. mutans prevalence in pre-school children with malocclusion of the Metropolitan region.

Proyecto (6)

ISAAC Phase III LatinAmerica (LA)
Estudio y análisis desigualdades en la Encuesta de Salut Cataluña (ESCA)
INTEROCC-Occupational Exposures And Brain Cancer
Interphone study on mobile phone use and brain cancer risk
CONTAMINACION INTRADOMICILIARIA COMO FACTOR DE RIESGO DE INFECCION RESPIRATORIA AGUDA=> ESTUDIO EN LACTANTES MENORES DE UN AGNO DE SANTIAGO SUR-ORIENTE
ROL DE LOS FACTORES DIETARIOS EN LA ETIOLOGIA DEL CANCER=> ESTUDIO DE CASOS-CONTROLES
34
Rodrigo Villegas

Jefe Programa de Bioestadística

Bioestadística

Universidad de Chile - Facultad de Medicina

Santiago, Chile

2
Alex Vargas

Profesor Asociado

Cirugia Oncologica y Maxilofacial

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

2
Pablo Romero

Profesor Asociado

Oftalmología

Universidad de Chile

Santiago, Chile

1
JUAN AGUILLON

PROFESSOR

IMMUNOLOGY PROGRAM

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

1
Maria Valenzuela

VICEDECANA DE INVESTIGACION Y POSTGRADO

UNIVERSIDAD DE LOS ANDES

Santiago, Chile

1
Jorge Soto

Asistente de Investigacion

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Daniel Soto

Profesional

Salud Ambiental

Instituto de Salud Publica de Chile

Santiago, Chile

1
Diego Díaz

Jefe (s)

ANDID

Instituto de Salud Pública de Chile

Santiago, Chile

1
rinat ratner

Directora carrera

Universidad del Desarrollo

santiago, Chile

1
Manuel Espinoza

Profesor Asociado

Salud Pública

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

1
Viola Pinto

Jefe

Hospital de niños Dr. Exequiel González Cortés

Santiago, Chile

1
Diego Catalán

Profesor Asistente

Programa Disciplinario de Inmunología

Universidad de Chile

Santiago, Chile

1
Lorena Salazar

Academico

Instituto Cs Biomédicas

Universidad Autónoma de Chile

Santiago, Chile

1
Carolina Llanos

Associate Professor

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Carolina Llanos

Profesor Asociado

Inmunología Clínica y Reumatología

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

1
OCTAVIO ARAVENA

Director Científico

I+D+i

MEDICEL SA

Santiago, Chile

1
Jimena Cuenca

Investigador/profesor

Facultad de Medicina

Universidad de Los Andes

Santiago, Chile

1
Bárbara Pesce

Profesora Asistente

ICBM

Universidad de Chile

Santiago, Chile