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Marcela Alejandra Hermoso Ramello

Full Professor

UNIVERSIDAD DE CHILE

Santiago, Chile

Líneas de Investigación


Innate immunity; mucosal immunity; infections and inflammation; Mechanisms of Bacterial Pathogenicity (Adhesion); Molecular Epidemiology; Cellular Microbiology (Bacteria-Cell interactions); Inflammatory Bowel Disease; Gastrointestinal Disorders.

Educación

  •  Biochemist, UNIVERSIDAD DE BUENOS AIRES. Argentina, 1987
  •  Biological Sciences in Physiology, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1997

Experiencia Académica

  •   Full Professor Full Time

    UNIVERSIDAD DE CHILE

    Medicine

    Santiago, Chile

    2017 - A la fecha

  •   ASSOCIATE PROFESSOR Full Time

    UNIVERSIDAD DE CHILE

    Medicina

    Santiago, Chile

    2007 - 2017

Experiencia Profesional

  •   Biochemist Full Time

    Hospital of the Institute of Cardiology, National Academy of Medicine, Buenos Aires, Argentina.

    Buenos Aires, Argentina

    1988 - 1989

  •   PhD Student Full Time

    Pontificia Universidad Catolica de Chile

    Santiago, Chile

    1991 - 1997

  •   Post-doc at Dr. Joseph Hume Laboratory Full Time

    Center of Biomedical Research Excellence (COBRE), School of Medicine, University of Nevada

    Reno, Estados Unidos

    2001 - 2001

  •   Post-doc at Dr. John A. Cidlowski Laboratory Full Time

    National Institutes of Environmental Health Sciences/National Institutes of Health, North Carolina

    Chile

    2002 - 2005

  •   Founder and Head Full Time

    The Innate Immunity Laboratory, Institute of Biomedical Sciences, Faculty of Medicine, Universidad de Chile

    Santiago, Chile

    2005 - 2006

  •   Assistant Professor Full Time

    Institute of Biomedical Sciences, Faculty of Medicine, Universidad de Chile.

    Santiago, Chile

    2005 - 2006

  •   Associate Professor Full Time

    Institute of Biomedical Sciences, Faculty of Medicine, Universidad de Chile

    Santiago, Chile

    2007 - A la fecha

  •   Associate Professor Full Time

    Institute of Biomedical Sciences, Faculty of Medicine, Universidad de Chile

    Chile

    2007 - A la fecha

  •   Associate Professor Full Time

    Institute of Biomedical Sciences, Faculty of Medicine, Universidad de Chile

    Santiago, Chile

    2007 - A la fecha

Formación de Capital Humano


PhD thesis mentoring

1) Glauben Landskron Ramos: Programa de Doctorado en Ciencias Biomédicas, Escuela de Postgrado, Facultad de Medicina, Universidad de Chile. Título de la Tesis: Papel del ATP extracelular en la liberación de IL33 por fibroblastos asociados a cáncer y el efecto de esta citoquina sobre la transición epitelio-mesénquima de una línea celular de adenocarcinoma colorectal. Directores: Marcela Hermoso Ramello y Guillermo Díaz. Thesis completed 2018.

2) Nayaret Chamorro: Programa de Doctorado en Microbiología, Universidad de Chile. Título de la Tesis: Caracterización de la microbiota de pacientes con enfermedades inflamatorias intestinales y su asociación con la respuesta inflamatoria. Directores: Roberto Vidal y Marcela Hermoso Ramello. Thesis completed 2019.

3) David Diaz Jiménez: Programa de Doctorado en Bioquímica, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile. Título de la Tesis: “Los Glucocorticoides Reprimen La Transcripción del Gen GR/NR3C1 Mediante Mecanismos Autoregulatorios Y Modificaciones Epigenéticas: Impacto En La Función Inflamatoria De Macrófagos Derivados de Monocitos”. Directores: Marcela Hermoso Ramello y John A. Cidlowski. Thesis completed 2019.

4) Daniela Parada. Programa de Doctorado en Ciencias Biomédicas, Escuela de Postgrado, Facultad de Medicina, Universidad de Chile. Título de la Tesis: “Rol de ácidos grasos de cadena corta en el perfil de macrófagos y la reparación epitelial en enfermedades inflamatorias intestinales” . Directores: Marcela Hermoso Ramello. Thesis to be completed 2019.

5) Karen Dubois Camacho: Programa de Doctorado en Ciencias Biomédicas, Escuela de Postgrado, Facultad de Medicina, Universidad de Chile. Título de la Tesis: MicroRNA 378a-3p, un nuevo regulador post-transcripcional de la variante soluble del receptor de IL33. Directores: Marcela Hermoso Ramello y Rodrigo Quera. Thesis completed 2017.

6) Mauricio Olivares Morales. Programa de Doctorado en Ciencias Biomédicas, Escuela de Postgrado, Facultad de Medicina, Universidad de Chile. Título de la Tesis: Rol de los glucocorticoides en la respuesta bactericida e inflamatoria de macrófagos infectados con la cepa de E. coli intracelular asociada a Enfermedad de Crohn. Directores: Marcela Hermoso Ramello y Roberto Vidal. Thesis completed 2017.

7) Tanya Neira. Programa de Doctorado en Ciencias Biomédicas, Escuela de Postgrado, Facultad de Medicina, Universidad de Chile. Título de la Tesis: Characterization of the inflammatory response mediated by PARP-1 in a rat model of perinatal asphyxia. Directores: Mario Herrera-Marschitz, Paola Morales y Marcela Hermoso. Thesis completed 2015.

8) Marjorie De la Fuente López. Programa de Doctorado en Ciencias Biomédicas, Escuela de Postgrado, Facultad de Medicina, Universidad de Chile. Título de la Tesis: Escherichia coli adherente invasiva en pacientes con enfermedad de Crohn: análisis de los mecanismos de invasión y evasión en células epiteliales y macrófagos. Directores: Marcela Hermoso Ramello y Roberto Vidal. Thesis completed 2014.

9) Daniela Araya. Programa de Doctorado en Ciencias Biomédicas, Escuela de Postgrado, Facultad de Medicina, Universidad de Chile. Título de la Tesis: Sistemas de captación de hierro como mecanismos de patogenicidad asociados a Escherichia coli adherente-invasiva aisladas de pacientes con Enfermedad de Crohn. Directores: Roberto Vidal y Marcela Hermoso Ramello. Candidata a doctora 2012.

10) Pedro Ayala. Programa de Doctorado en Farmacología, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile. Título de la Tesis: Rol de los fibroblastos y miofibroblastos cardíacos en el proceso inflamatorio mediado por TLR4. Directores: Guillermo Díaz y Marcela Hermoso Ramello. Thesis completed 2013

11) Patricia Langjahr. Programa de Doctorado en Ciencias Biomédicas, Escuela de Postgrado, Facultad de Medicina, Universidad de Chile. Título de la Tesis: Mecanismos moleculares involucrados en la producción de variantes solubles de TLR2. Director: Marcela Hermoso Ramello. Thesis completed 2013.

12) Lucia Núñez. Programa de Doctorado en Ciencias Biomédicas, Escuela de Postgrado, Facultad de Medicina, Universidad de Chile. Título de la Tesis: ST2: un nuevo mecanismo anti-inflamatorio de la acción de los glucocorticoides. Director: Marcela Hermoso Ramello. Thesis completed 2012.

13) Frano Malinarich. Biochemistry Program, Faculty of Chemistry and Pharmacy, Universidad de Chile. “Contribution of CCL4 to the oral tolerance mediated by intestinal T-gamma delta intraepithelial cells”. Thesis completed 2010.

14) Caroll Beltrán Muñoz. Biomedical Sciences Program, Faculty of Medicine, Universidad de Chile: “ST2 as an immunomodulator in inflammatory bowel diseases”. Thesis completed 2009.

Master degree direction

1) Mirit Bitran. Biochemist Program, Faculty of of Chemistry and Pharmacy, Universidad de Chile. Correlación entre la vía esteroidogénica intestinal y la respuesta al tratamiento con glucocorticoides en pacientes con colitis ulcerosa. Thesis in progress (to be graduated 2019)

2) Enzo Candia. Biological Science Program, mention immunology, Faculty of Medicine, Universidad de Chile. “Regulation of intestinal macrophages and monocytes by TLR2 in IBD”. Thesis completed 2011.

3) Maria José Herrera. Medical Science Program, mention immunology, Faculty of Medicine, Universidad de Chile. “Regulatory mechanisms of glucocorticoids on TLR4 expression in epithelium”. Thesis completed 2010.

Undergraduate thesis direction:

1) Gonzalo Vásquez: Universidad Tecnológica Metropolitana, Facultad Ciencias Naturales, Matemática Y del Medio Ambiente, Escuela de Industria Alimentaria y Biotecnología. "Producción y purificación de un scFv recombinante específico para la proteína ST2 soluble (sST2)". Thesis to be completed 2019.

2) Jonathan Lillo Barra. Universidad Tecnológica Metropolitana, Facultad Ciencias Naturales, Matemática Y del Medio Ambiente, Escuela de Industria Alimentaria y Biotecnología. "Producción de un anticuerporecombinante específico para la proteína ST2 soluble (sST2)". Thesis in progress (2019).

3) Estefhany Rubio C: Engineering in Biotechnology, Universidad Santo Tomás, Chile. “TLR2 processing by ADAMs methalloproteinases and ?-secretase complex“. Thesis completed 2013.

4) Diego Romero, Faculty of Medical Technology, Universidad de Chile. “ST2 and GRP78 expression in goblet cells in colon mucosa of ulcerative colitis patients (Expresión de ST2 y GRP78 en células caliciformes de pacientes con colitis ulcerosa).”. Thesis completed 2012.

5) Salvador Carvajal: Engineering in Biotechnology, Faculty of Sciences, Universidad de Chile. “Standardization of a capture ELISA for the measurement of soluble toll-like receptor 2 in human plasma”. Thesis completed 2010.

6) Karen Flores: Engineering in Biotechnology, Faculty of Engineering, Universidad de Chile. Thesis title: “Determination of operational parameters that allow definition of the mechanism of cell-penetrating TIRAP-Ala and TIRAP peptides internalization in HeLa cells”. Thesis completed 2010.

7) Nancy Farfán: Engineering in Biotechnology, Faculty of Sciences, Universidad de Chile. “Determination of soluble isoforms of Toll-like receptor 2 (TLR2) and characterization of its levels in plasma and biopsies from patients with inflammatory bowel disease”. Thesis completed 2013.

8) Rodrigo Valenzuela: Biochemistry, Faculty of Chemistry and Pharmacy, Universidad de Chile. Thesis title: “Participation of ST2 as a negative endogenous regulador in the TLR2 proinflammatory pathway”. Thesis completed 2008.

9) Ramón Pérez: Biochemistry, Faculty of Chemistry and Pharmacy, Universidad de Chile. Thesis title: “Transcriptional regulation of TLR4 by pro- and anti-inflammatory agents”. Thesis completed 2008.

10) Alexis Peralta: Biochemistry, Faculty of Chemistry and Pharmacy, Universidad de Chile. Thesis title: “ST2 and its relation to the immune Th1 and Th2 pattern in inflammatory bowel disease patients”. Co-Director: Dr. Rodrigo Quera. Thesis completed 2007.

11) Sergio Arancibia Z: Biochemistry, Faculty of Chemistry and Pharmacy, Universidad de Chile. Thesis title: “Regulation of TLR2 signaling pathway by PI3K upon bacterial infection”. Thesis completed 2006.

12) Pablo Olivero R: Biochemistry, Faculty of Chemistry and Pharmacy, Universidad de Chile. Thesis title: “Participation of PKC in hypotonicity induced by taurine“.Thesis completed 2002.


Premios y Distinciones

  •   Best Work Presentation

    SOCIEDAD CHILENA DE GASTROENTEROLOGIA

    Chile, 2011

    Genética de ST2 como factor predictivo de evolución desfavorable en pacientes con enfermedad inflamatoria intestinal. XXXVIII Congress of the Chilean Gastroenterology Society, Viña del Mar, Chile. Plenary talk, best work presentation award.

  •   Paper of the Year

    NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES

    Estados Unidos, 2004

    Paper destacado del instituto en el año, premio paper of the year


 

Article (63)

Aberrant MUC1 accumulation in salivary glands of Sjögren's syndrome patients is reversed by TUDCA in vitro.
Glucocorticoids mobilize macrophages by transcriptionally up-regulating the exopeptidase DPP4
Aberrant MUC1 accumulation in salivary glands of Sjögren’s syndrome patients is reversed by TUDCA in vitro
Editorial: Intestinal Homeostasis and Disease: A Complex Partnership Between Immune Cells, Non-Immune Cells, and the Microbiome
Inhibition of miR-378a-3p by Inflammation Enhances IL-33 Levels: A Novel Mechanism of Alarmin Modulation in Ulcerative Colitis
Interleukin 33/ST2 Axis Components Are Associated to Desmoplasia, a Metastasis-Related Factor in Colorectal Cancer
Synaptotagmin-1 overexpression under inflammatory conditions affects secretion in salivary glands from Sjogren's syndrome patients
Association of high 5-hydroxymethylcytosine levels with Ten Eleven Translocation 2 overexpression and inflammation in Sjögren's syndrome patients
Endoplasmic reticulum stress in autoimmune diseases: Can altered protein quality control and/or unfolded protein response contribute to autoimmunity? A critical review on Sjogrens syndrome
Glucocorticoids Impair Phagocytosis and Inflammatory Response Against Crohns Disease-Associated Adherent-Invasive Escherichia coli
Impaired IRE1 alpha/XBP-1 pathway associated to DNA methylation might contribute to salivary gland dysfunction in Sjogrens syndrome patients
A functional IL1RL1 variant regulates corticosteroid-induced sST2 expression in ulcerative colitis
Genetic Diversity and Virulence Determinants of Escherichia coli Strains Isolated from Patients with Crohn's Disease in Spain and Chile
Presence of intracellular Escherichia coli in patients with inflammatory bowel disease
Expression and function of toll-like receptor 4 and inflammasomes in cardiac fibroblasts and myofibroblasts: IL-1? synthesis, secretion, and degradation
Pro-inflammatory cytokines enhance ERAD and ATF6 pathway activity in salivary glands of Sjögren's syndrome patients
Soluble ST2 is a sensitive clinical marker of ulcerative colitis evolution
Crohn associated microbial communities associated to colonic mucosal biopsies in patients of the western Mediterranean
MUC1/SEC and MUC1/Y overexpression is associated with inflammation in Sjogren's syndrome
Perinatal Asphyxia Leads to PARP-1 Overactivity, p65 Translocation, IL-1 beta and TNF-alpha Overexpression, and Apoptotic-Like Cell Death in Mesencephalon of Neonatal Rats: Prevention by Systemic Neonatal Nicotinamide Administration
RNA helicase DDX3: at the crossroad of viral replication and antiviral immunity.
Salivary mucins induce a Toll-like receptor 4-mediated pro-inflammatory response in human submandibular salivary cells: are mucins involved in Sjogren's syndrome?
Chronic inflammation and cytokines in the tumor microenvironment.
Escherichia coli isolates from inflammatory bowel diseases patients survive in macrophages and activate NLRP3 inflammasome
Metalloproteinase-Dependent TLR2 Ectodomain Shedding is Involved in Soluble Toll-Like Receptor 2 (sTLR2) Production
Innate immunity modulation by the IL-33/ST2 system in intestinal mucosa.
Sjögren's syndrome and the epithelial target: a comprehensive review.
Aberrant localization of fusion receptors involved in regulated exocytosis in salivary glands of Sjogren's syndrome patients is linked to ectopic mucin secretion
Decreased salivary sulphotransferase activity correlated with inflammation and autoimmunity parameters in Sjogren's syndrome patients
Effect of the electrostatic potential on the internalization mechanism of cell penetrating peptides derived from TIRAP
Increased production of soluble TLR2 by lamina propria mononuclear cells from ulcerative colitis patients
Mechanotransduction and epigenetic control in autoimmune diseases (vol 10, pg 175, 2011)
Toll-like receptor 4 gene polymorphism influences dendritic cell in vitro function and clinical outcomes in vaccinated melanoma patients
"Corrigendum to ""Mechanotransduction and epigenetic control in autoimmune diseases"" [J. Autoimmun. Rev. 10 (2011) 175-179]"
[Possible association between Mycobacterium avium subsp paratuberculosis infection and Crohn's disease].
Alterations in Type I Hemidesmosome Components Suggestive of Epigenetic Control in the Salivary Glands of Patients With Sjogren's Syndrome
Changes in Rab3D Expression and Distribution in the Acini of Sjogren's Syndrome Patients Are Associated With Loss of Cell Polarity and Secretory Dysfunction
Heat-Shock Induction of Tumor-Derived Danger Signals Mediates Rapid Monocyte Differentiation into Clinically Effective Dendritic Cells
Mechanotransduction and epigenetic control in autoimmune diseases.
Phosphatidylinositol 3-kinase interacts with the glucocorticoid receptor upon TLR2 activation
Soluble ST2: A new and promising activity marker in ulcerative colitis
Characterization of the Novel ST2/IL-33 System in Patients with Inflammatory Bowel Disease
Constant TCR triggering suggests that the TCR expressed on intestinal intraepithelial gamma delta T cells is functional in vivo
Disruption of Tight Junction Structure in Salivary Glands From Sjogren's Syndrome Patients Is Linked to Proinflammatory Cytokine Exposure
An update on the pathogenesis of celiac disease Enfermedad celíaca y su patogenia
Gene expression and chromosomal location for susceptibility to Sjogren's syndrome
GENE EXPRESSION AND CHROMOSOMAL LOCATION FOR SUSCEPTIBILITY TO SJOGRENS SYNDROME
Peripheral cytokine profile in Chilean patients with Crohn's disease and ulcerative colitis
PERIPHERAL CYTOKINE PROFILE IN CHILEAN PATIENTS WITH CROHNS DISEASE AND ULCERATIVE COLITIS
Regulation of Cell Survival by Resveratrol Involves Inhibition of NF kappa B-Regulated Gene Expression in Prostate Cancer Cells
Severe alterations in expression and localisation of alpha 6 beta 4 integrin in salivary gland acini from patients with Sjogren syndrome
A ROLE FOR ST2 IN MAST CELL DEGRANULATION: A CONTRIBUTORY FACTOR IN IBD
DETERMINACION DE LA QUIMIOQUINA CCL4 MURINA EN CELULAS T TOTALES Y GAMA DELTA INTRAEPITELIALES INTESTINALES
IL-23R Arg381Gln polymorphism in Chilean patients with inflammatory bowel disease
Effect of oestradiol and progesterone on the instant and directional velocity of microsphere movements in the rat oviduct: gap junctions mediate the kinetic effect of oestradiol
17-beta-Estradiol upregulates COX-2 in the rat oviduct
Inhibition of nuclear factor-kappa B enhances the capacity of immature dendritic cells to induce antigen-specific tolerance in experimental autoimmune encephalomyelitis
NOD2/CARD15 and Toll-like 4 receptor gene polymorphism in Chilean patients with inflammatory bowel disease
Cell volume regulation in response to hypotonicity is impaired in HeLa cells expressing a protein kinase C alpha mutant lacking kinase activity
ClC-3 is a fundamental molecular component of volume-sensitive outwardly rectifying Cl- channels and volume regulation in HeLa cells and Xenopus laevis oocytes
Functional inhibition of native volume-sensitive outwardly rectifying anion channels in muscle cells and Xenopus oocytes by anti-CIC-3 antibody
Platelet activating factor increases ciliary activity in the hamster oviduct through epithelial production of prostaglandin E-2
Identification of gap junctions in the oviduct and regulation of connexins during development and by sexual hormones

Abstract (7)

ARE SALIVARY MUCINS ABLE TO TRIGGER A PROINFLAMMATORY RESPONSE?
Identification of Intracellular Escherichia Coli (IEC), Associated With Crohn's Disease, in Other Intestinal Pathologies
Rapid protocol to generate tolerogenic dendritic cells using microbial lipopeptide (BLP).
Inhibition of native volume-senstive chloride currents and RVD in HeLa cells and Xenopus laevis oocytes by ClC-3 antisense
Functional inhibition of native and recombinant volume-sensitive outwardly rectifying anion channels by CLC-3 antibody
Functional knockout of native and recombinant volume-sensitive outwardly rectifying anion channels (VSOACs) by Anti-ClC3 antibody
Regulation of smooth muscle activity in the oviduct by sex hormones

BookWhole (2)

Current knowledge in inflammatorty bowel diseases immunopathogenesis
Nutrition and inflammatory bowel disease

ConferencePaper (1)

Effect of the electrostatic potential on the internalization mechanism of cell penetrating peptides

Errata (2)

Escherichia coli isolates from inflammatory bowel diseases patients survive in macrophages and activate NLRP3 inflammasome (vol 304, pg 384, 2014)
Peripheral cytokine profile in Chilean patients with Crohn's disease and ulcerative colitis (vol 1, pg 33, 2008)

Proyecto (16)

Development, production and characterization of a recombinant human antibody against the soluble variant of ST2 (sST2) with therapeutic potential for the treatment of ulcerative colitis
Gastrointestinal diseases: loss of gut homeostasis due to the complex interaction between genetics, immune response and microbiota
Role of corticoids signaling on intestinal steroidogenesis in ulcerative colitis
IL-33 inflammatory cycle=> Role in Colangiocarcinoma metastasis and potential application as a therapeutic target.
Microarray analysis of AIEC infected THP-1 cells=> effect of glucocorticoids
Caracterización del MicroRNA 378a-3p en Pacientes con Colitis Ulcerosa y su Potencial Asociación con la Terapia Esteroidal.
Interacción patógeno-hospedero=> la necesidad de generar conocimiento de cómo patógeno promueve enfermedades inflamatorias y el cáncer
The atlas of the HIV-1 genomic messenger ribonucleoprotein (mrnp) complex.
CELLULAR AND MOLECULAR MECHANISMS RELEVANT IN THE INTERACTION OF CLINICAL ISOLATES OF ADHERENT INVASIVE ESCHERICHIA COLI (AIEC) WITH EPITHELIAL CELLS OR MACROPHAGES IN CROHN S DISEASE
Single nucleotide polymorphisms (SNPs), located in the promoter region of ST2 gene, correlate with sST2 circulating levels and influence IBD severity.
Identificación y caracterización de la cepa intestinal E. coli invasiva derivada de pacientes con enfermedad de Crohn.
ROLE OF ST2/IL-33 SYSTEM IN MUCOSAL INFLAMMATION AND INFLAMMATORY BOWEL DISEASES PATHOGENIA
Regulation of inflammatory responses of monocyte/macrophages induced by an agonist of TLR2 in human intestine.
CARACTERIZACION DE MECANISMOS POSIBLES DE PROCESAMIENTO DE TLR2 Y SU PAPEL INMUNOREGULADOR EN LA ENFERMEDAD INFLAMATORIA INTESTINAL
MODULACION DE LA SENSIBILIDAD A GLUCOCORTICOIDES EN INFECCIONES AGUDAS. ROL DE RECEPTORES TIPO TOLL.
CARACTERIZACION DE LA FUNCION INMUNO REGULADORA DE ST2 EN LAS ENFERMEDADES INFLAMATORIAS INTESTINALES.

Review (14)

Short Chain Fatty Acids (SCFAs)-Mediated Gut Epithelial and Immune Regulation and Its Relevance for Inflammatory Bowel Diseases
Glucocorticosteroid therapy in inflammatory bowel diseases: From clinical practice to molecular biology
RNA helicase DDX3: at the crossroad of viral replication and antiviral immunity
The IL-33/ST2 axis: Role in health and disease
Chronic Inflammation and Cytokines in the Tumor Microenvironment
Innate Immunity Modulation by the IL-33/ST2 System in Intestinal Mucosa
Oral dryness in Sjogren's syndrome patients. Not just a question of water
Sjogren's syndrome and the epithelial target: A comprehensive review
Mechanotransduction and epigenetic control in autoimmune diseases
Possible association between Mycobacterium avium subsp paratuberculosis infection and Crohn's disease
An update on the pathogenesis of celiac disease
Enfermedad celíaca y su patogenia
Enfermedad inflamatoria intestinal: Una mirada inmunológica
Inflammatory bowel diseases: An immunological approach
94
Marcela Hermoso

Full Professor

School of Medicine

UNIVERSIDAD DE CHILE

Santiago, Chile

26
Rodrigo Quera

Gastroenterólogo

Gastroenterología

CLÍNICA LAS CONDES, SERVICIO DE GASTROENTEROLOGÍA

Santiago, Chile

16
Claudio Molina

Director Investigación

Investigación

Universidad San Sebastián

Santiago, Chile

13
Sergio González

Profesor titular

Patología General y Oral

Universidad Mayor

Santiago, Chile

13
ULISES URZUA

Assistant Professor

ICBM

UNIVERSIDAD DE CHILE

Santiago, Chile

12
Isabel Castro

Profesor Asistente

Tecnología Médica

Universidad de Chile

Santiago, Chile

9
Marjorie De la Fuente

Investigadora Clinica

Direccion Academica

Clinica Las Condes

Santiago , Chile

8
Andrew Quest

Full Professor

Biologia Celular y Molecular

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

8
David Diaz

Asistente de Investigación

Instituto de Ciencias Biomédicas, Facultad de Medicina

Universidad de Chile

Santiago, Chile

6
Sergio Aguilera

Reumatólogo

CLÍNICA INDISA

Santiago, Chile

5
roberto vidal

Head of Pathogenic Escherichia coli Laboratory

Director Microbiology and Mycology Program

UNIVERSIDAD DE CHILE

Santiago, Chile

5
Maria González

Academico

FACULTAD DE MEDICINA - UNIVERSIDAD DE CHILE

Santiago, Chile

5
Caroll Beltrán

Profesor Asistente, Investigador Principal

Medicina

Universidad de Chile, Fac Medicina

SANTIAGO, Chile

4
Lucia Nuñez

ENCARGADA DE VALORACION

FACULTAD DE CIENCIAS VETERINARIAS Y PECUARIAS

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

4
Manuel Alvarez

Gastroenterologist and Chief of Institute of Medicine

Gastroenterology

Pontificia Universidad Católica de Chile

Santiago, Chile

4
María Barrera

Profesor Asistente

Odontología

Universidad San Sebastián, Facultad de Odontología

Santiago, Chile

3
Amelina Albornoz

Post doctorado

Virología Molecular

Fundación Ciencia & Vida

Santiago, Chile

2
Andrés Tittarelli

Investigador

Universidad Tecnológica Metropolitana

Santiago, Chile

2
Gerald Zapata

DEPARTAMENTO DE QUÍMICA INORGÁNICA Y ANALÍTICA FACULTAD DE CIENCIAS QUÍMICAS Y FARMACÉUTICAS UNIVERSIDAD DE CHILE

Santiago, Chile

2
Luisa Herrera

Profesor Asociado

Incstituto de Ciencias Biomédicas, Programa de Genética Humana

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA-ICBM

Santiago, Chile

2
Nancy Farfán

Post-doc.

Farmacología

Universidad de Chile

Santiago, Chile

2
Ziomara Gerdtzen

Profesora Asociada

Departamento de Ingeniería Química, Biotecnología y Materiales

Universidad de Chile

Santiago, Chile

2
DENISSE SEPULVEDA

Postdoc

Universidad Mayor de Chile

Santiago, Chile

2
Fermín González

Profesor Asociado

universidad de chile

Santiago, Chile

2
Glauben Landskron

Postdoctoral Researcher Fondecyt 3190931

Academic Direction

Clinica Las Condes

Santiago, Chile

1
Fernando Valiente

Profesor Asociado

ICBM

Universidad de Chile

Santiago, Chile

1
Edgardo Rojas-Mancilla

Académico e Investigador

Ciencias Químicas y Biológicas

Universidad Bernardo OHiggins

Santiago, Chile

1
Benjamín Erranz

Investigador-Docente

Instituto de Ciencias e Innovación en Medicina

Universidad del Desarrollo

Santiago, Chile

1
JUAN AGUILLON

PROFESSOR

IMMUNOLOGY PROGRAM

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

1
Lorena Salazar

Academico

Instituto Cs Biomédicas

Universidad Autónoma de Chile

Santiago, Chile

1
Daniela Simian

Enfermera de Investigación

Subdirección de Investigación

Clínica Las Condes

Santiago, Chile

1
Raúl Vivar

Profesor Asistente

Universidad de Chile

Santiago, Chile

1
Ricardo Soto

PROFESOR ASOCIADO

FACULTAD DE MEDICINA

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

1
daniel hevia

Investigador PhD

Inmunologia

Universidad de Chile

santiago, Chile

1
Mario Herrera-Marschitz

Profesor titular

Mol. & Clin. Pharmacology

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA, PROGRAMA FARMACOLOGIA MOLECULAR & CLINICA, ICBM

Santiago, Chile

1
Paola Morales

Profesor Asociado

Programa Farmacología Molecular & Clínica, ICBM,

Universidad de Chile

Santiago, Chile

1
Cristian Falcón

Urólogo

Hospital San Juan de Dios

Santiago, Chile

1
Felipe Del Canto

Profesor Asistente

Programa de Microbiologia y Micologia

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

SANTIAGO, Chile

1
Mercedes López

Profesora Asociada

Instituto de Ciencias Biomédicas

Universidad de chile

Santiago, Chile

1
Claudia Muñoz

Postdoctorado

Universidad de Chile

Santiago, Chile

1
ARTURO FERREIRA

FULL PROFESSOR, CHAIR IMMUNOLOGY DISCIPLINARY PROGRAM

IMMUNOLOGY

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

1
Juan Saez

Professor

Instituto de Neurociencias

Universidad de Valparaiso

Valparaíso, Chile

1
José Salgado

Associate Professor

Chemical Engineering, Biotechnology and Materials

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Nelson Barrera

Associate Professor

Physiology

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

1
Steffen Härtel

Full Professor

Instituto de Ciencias Biomédicas

University of Chile

Santiago, Chile

1
Sergio Arancibia

Medical Science Liaison

Medical Affairs

Johnson & Johnson (Janssen Pharmaceutical)

Santiago, Chile

1
Patricio Retamal

Profesor Asistente

Medicina Preventiva Animal

FACULTAD DE CIENCIAS VETERINARIAS Y PECUARIAS, UNIVERSIDAD DE CHILE

Santiago, Chile

1
Francisca Bronfman

Full Professor

Instituto de Ciencias Biomédicas

Universidad Andrés Bello

Santiago, Chile

1
Lisette Leyton

Full Professor

Cell and Molecular Biology

FACULTAD DE MEDICINA UNIVERSIDAD DE CHILE

Santiago, Chile

1
Raquel Aguilera

PROFESOR ASISTENTE

INMUNOLOGÍA CLÍNICA Y REUMATOLOGÍA

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

1
Ariel Castro

Académico

Psiquiatria y Salud Mental

Hospital Clinico Universidad de Chile

Santiago, Chile

1
Daniela Parada

Asistente de investigación

Programa Disciplinario de Inmunología

Universidad de Chile

Santiago, Chile

1
Mariana Rios

Investigador

Facultad de Ciencias Biológicas

pontificia Universidad Católica de Chile

Santiago, Chile

1
Andres Stutzin

Full Professor

ICBM

FACULTAD DE MEDICINA UNIVERSIDAD DE CHILE

Santiago, Chile

1
Ana Riveros

Profesor Asistente

Departamento de Química Farmacológica y Toxicológica

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS QUIMICAS Y FARMACÉUTICAS

Santiago, Chile

1
Pablo Olivero

Profesor Adjunto

Patologia y Fisiologia

Universidad de Valparaiso

Viña del Mar, Chile

1
Bernardo Morales

Profesor titular

Biologia

Universidad de Santiago de Chile

Santiago, Chile

1
Leonel Muñoz

Profesor Auxiliar

Escuela de Medicina

Universidad de Valparaíso

Viña del Mar, Chile