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Gerald Amílcar Zapata Torres

Profesor Asociado

Universidad de Chile

Santiago, Chile

molecular modeling of biological systems; chemical reactivity using quantum mechanics methodologies; molecular modeling of protein ligand interactions; computational biology

Química Teórica Computacional / Química Médica, UNIVERSIDAD DE CHILE. Chile, 2002
Química, UNIVERSIDAD DE CHILE. Chile, 1991

Prof. Asociado Full Time

UNIVERSIDAD DE CHILE

Ciencias Químicas y Farmaceúticas

Santiago, Chile

2005 - A la fecha

Inserción a la academia Conicyt Full Time

Universidad de Chile

Chile

2005 - 2008

Reconocimiento de Universidad de Chile

UNIVERSIDAD DE CHILE

Chile, 2013

A los 52 investigadore(as) y grupos que publicaron sus trabajos como autor correspondiente, en revistas internacionales ISI-WOS ubicadas en el 10% superior de sus respectivas disciplinas y que son reconocidas internacionalmente como de excelencia


Identification of VEGFR2 as the Histatin-1 receptor in endothelial cells Silva, Patricio; Criollo, Alfredo; Torres, Vicente A. Article ISI BIOCHEMICAL PHARMACOLOGY (2022)
5-HT2 Receptor Subfamily and the Halogen Bond Promise Cassels, Bruce K.; Jaque, Pablo Article ISI JOURNAL OF CHEMICAL INFORMATION AND MODELING (2021)
Major Histocompatibility Complex Class I-Related Chain A (MICA) Allelic Variants Associate With Susceptibility and Prognosis of Gastric Cancer Article FRONTIERS IN IMMUNOLOGY (2021)
Dibenzofuranylethylamines as 5-HT(2A/2C )Receptor Agonists Matthies D.J. Article ISI SCOPUS ACS OMEGA (2020)
Influence of DM beta CD on the Interaction of Copper(II) Complex of 6-Hydroxychromone-3-carbaldehyde-3-hydroxybenzoylhydrazine with ctDNA GÃ³mez-Machuca H. Article ISI SCOPUS ACS OMEGA (2020)
Molecular modeling of salsolinol, a full G(i) protein agonist of the mu-opioid receptor, within the receptor binding site BerrÃos-CÃ¡rcamo P. Article ISI SCOPUS CHEMICAL BIOLOGY & DRUG DESIGN (2019)
Intense White Molecular Fluorescence from Naphthoxazole-Quinoline Derivatives Valdebenito, S.; Gidi Y.; Zanocco, A. L. Article ISI SCOPUS Photochemistry and Photobiology (2018)
Racemic salsolinol and its enantiomers act as agonists of the mu-opiod receptor by activating the Gi protein adenylate cyclase pathway Berrios-Carcamo, P.; Quintanilla, E.; Herrera-Marchitz, M.; Vasilou, V.; Zapata-Torres, G.; Rivera-Meza, M. Article FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2017)
Racemic Salsolinol and its Enantiomers Act as Agonists of the mu-Opioid Receptor by Activating the Gi Protein-Adenylate Cyclase Pathway Herrera-Marschit M.; Vasiliou V. Article ISI SCOPUS FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2017)
Synthesis and Docking of Novel 3-Indolylpropyl Derivatives as New Polypharmacological Agents Displaying Affinity for 5-HT1AR/SERT Silva-Matus, Paul; Chung, Hery; Möller-Acuña, Patricia; Reyes-Parada, Miguel Article ISI SCOPUS ARCHIV DER PHARMAZIE (2017)
Synthesis and Docking of Novel 3-indolylpropyl derivatives as new polypharmacological agents displaying affinity for 5-HT1AR/SERT Pessoa-Mahana, H.; Silva-Matus, P.; Pessoa-Mahana, D.; Chung, H.; Iturriaga-Vasquez, P.; Quiroz, G.; Moller-Acuna, P.; Zapata-Torres, G.; Saitz-Barria, V.; Araya-Maturana, R.; Reyes-Parada, M. Article ARCHIV DER PHARMAZIE (2017)
Spectroscopic studies of the interaction of 3-(2-thienyl)-[1,2,3]triazolo[1,5-a]pyridine with 2,6-dimethyl-beta-cyclodextrin and ctDNA Cifuentes, T.; Cayupi, J.; Ballesteros, Rafael; Ballesteros-Garrido, Rafael Article ISI SCOPUS ORGANIC & BIOMOLECULAR CHEMISTRY (2016)
Spectroscopic studies of the interaction of 3-(2-thienyl)-[1,2,3]triazolo[1,5-a]pyridine with 2,6-dimethyl-beta-cyclodextrin and ctDNA Cifuentes, T.; Cayupi, J.; Celis-Barros, C.; Zapata-Torres, G.; Ballesteros, R.; Ballesteros-Garrido, R.; Abarca, B.; Jullian, C. Article ORGANIC AND BIOMOLECULAR CHEMISTRY (2016)
Why p-OMe- and p-Cl-β-Methylphenethylamines Display Distinct Activities upon MAO-B Binding, Fierro, A; Edmondson D.E.; Celis-Barros, C.; Rebolledo-Fuentes, M.; Zapata-Torres, G. Article PLOS ONE (2016)
Why p-OMe- and p-Cl-beta-Methylphenethylamines Display Distinct Activities uponMAO-B Binding Fierro, A. Article ISI SCOPUS PLOS ONE (2016)
"Interaction of LD14 and TiO2 in dye-sensitized solar-cells (DSSC): A density functional theory study" Mendizabal, F. ; Lopez, A. ; Arratia-Perez, R.; Zapata-Torres, G. Article Computational and Theoretical Chemistry (2015)
Revealing Monoamine Oxidase B Catalytic Mechanisms by Means of the Quantum Chemical Cluster Approach G. Zapata-Torres, A. Fierro, G. Barriga-Gonzãlez, J.C. Salgado, C. Celis-Barros, Article Journal of Chemical Information and Modeling (2015)
"Supramolecular assemblies of phenyl-pyridyl-triazolopyridine and beta-cyclodextrin as sensor of divalent cations in aqueous solution." Jullian, C.; Fernandez-Sandoval, S. ; Celis-Barros, C.; Abarca, B.; Ballesteros, R.; Zapata-Torres, G. Article Carbohydrate Polymers (2015)
Experimental and theoretical studies of the photophysics of 7-amino-3-phenyl-2H-benzo[b] [1,4]oxazin-2-one in homogeneous solvents and beta-cyclodextrin aqueous solutions Valdebenito, S.; Zapata-Torres, G; Lemp E.; Zanocco, AL Article ISI AFINIDAD. Journal of Chemical Engineering Theoretical and Applied Chemistry (2015)
Interaction of LD14 and TiO2 in dye-sensitized solar-cells (DSSC): A density functional theory study Mendizabal, F; Lopez A.; Arratia-Perez, R; Zapata-Torres, G Article ISI SCOPUS Computational and Theoretical Chemistry (2015)
Molecular dynamics simulation of halogen bonding mimics experimental data for cathepsin L inhibition 1. Celis-Barros, C.; Cassels, B.K.; Saavedra-Rivas, L.; Salgado, J. C.; Zapata-Torres, G. Article Journal of Computer-Aided Molecular Design (2015)
Molecular dynamics simulation of halogen bonding mimics experimental data for cathepsin L inhibition Celis-Barros, C; Saavedra-Rivas L.; Salgado, J. C.; Cassels, B.K.; Zapata-Torres, G Article ISI SCOPUS JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2015)
Revealing Monoamine Oxidase B Catalytic Mechanisms by Means of the Quantum Chemical Cluster Approach Zapata-Torres, G; Fierro, A.; Barriga-Gonzalez, G; Salgado JC; Celis-Barros, C Article ISI SCOPUS JOURNAL OF CHEMICAL INFORMATION AND MODELING (2015)
Supramolecular assemblies of phenyl-pyridyl-triazolopyridine and beta-cyclodextrin as sensor of divalent cations in aqueous solution Jullian C.; Fernandez-Sandoval S.; Celis-Barros, C; Abarca, B; Ballesteros, R; Zapata-Torres, G Article ISI SCOPUS CARBOHYDRATE POLYMERS (2015)
“Revealing Monoamine Oxidase B Catalytic Mechanisms by Means of the Quantum Chemical Cluster Approach”. Zapata-Torres, G; Fierro; A.; Barriga-González, G.; J. Cristian Salgado, J.C.; Celis-Barros, C. Article J. Chem. Inf. Model. (2015)
Detecting Ni(II) in aqueous solution by 3-(2-pyridyl)-[1,2,3]triazolo[1,5-a]pyridine and dimethyl-beta-cyclodextrin Jullian, C. Fernandez-Sandoval, S.; Rojas-Aranguiz, M.; Gomez-Machuca, H.; Salgado-Figueroa, P.; Celis-Barros, C.; Zapata-Torres, G.; Adam, R.; Abarca, B. Article Carbohydrate Polymer (2014)
A novel dihydropyridine with 3-aryl meta-hydroxyl substitution blocks L-type calcium channels in rat cardiomyocytes Galves, D.; Zapata-Torres G.; Hidalgo, J.; Ayala, P.; Pedrozo, Z.; Ibarr, C.; Diaz-Araya, G.; Vicencio, J.M.; Nuñez-Vergara, L.; Lavandero, S.; Hall, R. A. Article Toxicology and Applied Pharmacology (2014)
A novel dihydropyridine with 3-aryl meta-hydroxyl substitution blocks L-type calcium channels in rat cardiomyocytes Galvis-Pareja, D; Zapata-Torres, G; Hidalgo J.; Ayala, P; pedrozo, Z; Ibarra, C; Diaz-Araya, G; Hall, AR; Nunez-Vergara, L; Lavandero S. Article ISI SCOPUS TOXICOLOGY AND APPLIED PHARMACOLOGY (2014)
Detecting Ni(II) in aqueous solution by 3-(2-pyridyl)-[1,2,3]triazolo[1,5-a]pyridine and dimethyl-beta-cyclodextrin Jullian C.; Fernandez-Sandoval S.; Rojas-Aranguiz, M; Gomez-Machuca, H; Salgado-Figueroa, P; Celis-Barros, C; Zapata-Torres, G; Adam, R.; Abarca, B Article ISI SCOPUS CARBOHYDRATE POLYMERS (2014)
Factors affecting the competitive reduction of 8,8-dimethylnaphthalene-1,4,5(8H)-trione in a Diels-Alder cycloaddition with hydroxysulfinyldienes Almodovar, I; Cardona W.; Delgado-Castro, T; Zapata-Torres, G; Araya-Maturana, R Article ISI SCOPUS JOURNAL OF THE IRANIAN CHEMICAL SOCIETY (2014)
“Factors affecting the competitive reduction of 8,8-dimethylnaphthalene-1,4,5(8H)-trione in a Diels-Alder cycloaddition with hydroxysulfinyldienes. Almodovar, I.; Cardona, W.; Delgado-Castro, T.; Zapata-Torres, G.; Caroli- Rezende, M.; Araya-Maturana, R. Article Journal of the Iranian Chemical Society (2014)
Remote Regio- and Stereocontrol by the Sulfinyl Group. Diels-Alder Reaction of Sulfinyl Dienols and 8,8-Dimethylnaphthalene-1,4,5(8H)-Trione Almodovar, I; Cardona, W; Delgado-Castro, T; Zapata-Torres, G; Rezende, MC; Araya-Maturana, R; Maestro, MC; García Ruano, JL Article Tetrahedron: Asymmetry (2013)
Remote regio- and stereocontrol by the sulfinyl group: Diels-Alder reaction of sulfinyl dienols and 8,8-dimethylnaphthalene-1,4,5(8H)-trione Almodovar, I; Cardona W.; Delgado-Castro, T; Zapata-Torres, G; Araya-Maturana, R; Maestro, MC; Ruano, JLG Article ISI SCOPUS Tetrahedron Asymmetry (2013)
Selected hydroxycoumarins as antioxidants in cells: physicochemical and reactive oxygen species scavenging studies Perez-Cruz, F; Villamena, FA; Zapata-Torres, G; Das A.; Headley, CA; Quezada E.; Lopez-Alarcon, C; Olea Azar C. Article ISI SCOPUS JOURNAL OF PHYSICAL ORGANIC CHEMISTRY (2013)
Selected hydroxycoumarins as antioxidants in cells: physicochemical and reactive oxygen species scavenging studies Pérez-Cruz, F.; Villamena, F.A.; Zapata-Torres, G.; Das, A.; Headley, C.A.; Quezada, E.; Lopez-Alarcon, C.; Olea-Azar, C. Article Journal of Physical Organic Chemistry (2013)
Structural elucidation of supramolecular alpha-cyclodextrin dimer/aliphatic monofunctional molecules complexes Barrientos, L; Lang, E.; Zapata-Torres, G; Celis-Barros, C; Orellana, C; Jara P.; Yutronic, N Article ISI SCOPUS Journal of Molecular Modeling (2013)
Structural Elucidation of Supramolecular Alpha-Cyclodextrin Dimer/Aliphatic Monofunctional Molecules Complexes Barrientos, L; Lang, E; Zapata-Torres, G; Celis-Barros, C; Orellana, C; Jara, P; Yutronic, N. Article Journal of Molecular Modeling (2013)
Synthesis, docking and pharmacological evaluation of novel homo- and hetero-bis 3-piperazinylpropylindole derivatives at SERT and 5-HT1A receptor Pessoa-Mahana H.; Gonzalez-Lira, C; Fierro, A.; Zapata-Torres, G; Pessoa-Mahana, CD; Ortiz-Severin, J; Iturriaga-Vasquez, P; Reyes-Parada, M; Silva-Matus, P; Saitz-Barria, C; et al. Article ISI SCOPUS Bioorganic and Medicinal Chemistry (2013)
Synthesis, docking and pharmacological evaluation of novel homo- and hetero-bis 3-piperazinylpropylindole derivatives at SERTand 5-HT1A receptor Pessoa-Mahana, H.; Gonzalez-Lira, C.; Fierro, A.; Zapata-Torres, G.; Pessoa-Mahana, D.; Ortiz-Severin, J.; Iturriaga-Vasquez, P.; Reyes-Parada, M.; Silva-Matus, P.; Saitz-Barria, C.; Araya-Maturana, R. Article Bioorganic & Medicinal Chemistry (2013)
Biological and chemical study of fused tri- and tetracyclic indazoles and analogues with important antiparasitic activity Zapata G. A.; Lapier, M.; Mura F.; Aguilera-Venegas, B; Maya J.D. Article ISI SCOPUS SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2012)
Biological and chemical study of fused tri- and tetracyclic indazoles and analogues with important antiparasitic activity Diaz-Urrutia, CA.; Olea-Azar, CA; Zapata-Torres, G. Article Spectrochimica Acta Part A-Molecular and Biomolecular Spectroscopy (2012)
Effect of the electrostatic potential on the internalization mechanism of cell penetrating peptides Flores-Olave, K; Salgado, JC; Zapata-Torres, G; Gonzalez, MJ; Hermoso, MA Article Biotechnology and Bioprocess Engineering Journal (2012)
Effect of the electrostatic potential on the internalization mechanism of cell penetrating peptides derived from TIRAP Salgado, J. C.; Zapata-Torres, G; Gerdtzen, Z.P.; Gonzalez, M. J.; Hermoso M.A. Article ISI SCOPUS Biotechnology and Bioprocess Engineering (2012)
Influence of Protonation on Substrate and Inhibitor Interactions at the Active Site of Human Monoamine Oxidase-A Zapata-Torres, G; Fierro, A.; Miranda-Rojas, S; Guajardo, C.; Saez-Briones, P; Salgado, J. C.; Celis-Barros, C Article ISI SCOPUS JOURNAL OF CHEMICAL INFORMATION AND MODELING (2012)
Influence of Protonation on Substrate and Inhibitor Interactions at the Active Site of Human Monoamine Oxidase-A Zapata-Torres, G*; Fierro-Huerta, A; Miranda-Rojas, S; Guajardo, C; Sáez-Briones, P; Salgado, JC; Celis-Barros, C. Article Journal of Chemical Information and Modeling (2012)
Synthesis, 5-Hydroxytryptamine(1A) Receptor Affinity and Docking Studies of 3-[3-(4-Aryl-1-piperazinyl)-propyl]-1H-Indole Derivatives Pessoa-Mahana H.; Nunez, CU; Araya-Maturana, R; Barria, CS; Zapata-Torres, G; Pessoa-Mahana, CD; Iturriaga-Vasquez, P; Mella-Raipan J.; Reyes-Parada, M; Celis-Barros, C Article ISI CHEMICAL PHARMACEUTICAL BULLETIN (2012)
Synthesis, 5-Hydroxytryptamine(1A) Receptor Affinity and Docking Studies of 3-[3-(4-Aryl-1-piperazinyl)-propyl]-1H-Indole Derivatives 12. Pessoa-Mahana, H.; Ugarte Nunez, C; Araya-Maturana, R, Zapata-Torres, G, Celis-Barros, C. Article Chemical & Pharmaceutical Bulletin (2012)
Synthesis, Docking Studies and Biological Evaluation of Benzo[b]thiophen-2-yl-3-(4-arylpiperazin-1-yl)-propan-1-one Derivatives on 5-HT1A Serotonin Receptors Pessoa-Mahana H.; Recabarren-Gajardo G.; Zapata-Torres, G; Araya-Maturana, R Article ISI SCOPUS MOLECULES (2012)
Synthesis, Docking Studies and Biological Evaluation of Benzo[b]thiophen-2-yl-3-(4-arylpiperazin-1-yl)-propan-1-one Derivatives on 5-HT1A Serotonin Receptors Pessoa-Mahana, H.; Recabarren-Gajardo, G.; Fiedler-Temer, J; Zapata-Torres, G. Article Molecules (2012)
Phosphatidylinositol 3-kinase interacts with the glucocorticoid receptor upon TLR2 activation Arancibia, S; Benítez, D; Núñez, LE; Jewell, CM; Langjhar, P; Candia, E; Zapata-Torres, G; Cidlowski, JA; González, M-J; Hermoso, MA. Article Journal of Cellular and Molecular Medicine (2011)
Phosphatidylinositol 3-kinase interacts with the glucocorticoid receptor upon TLR2 activation Arancibia S.; Benitez D.; Langjahr P.; Candia, E.; Hermoso M.A.; Jewell C.M.; Cidlowski, J.A.; Zapata-Torres, G; Gonzalez, M. J. Article ISI SCOPUS Journal of Cellular and Molecular Medicine (2011)
Inclusion Complexes of Cyclodextrins with Galangin: a Thermodynamic and Reactivity Study Jullian, C; Alfaro, M; Zapata-Torres, G; Olea-Azar, C. Article Journal of Solution Chemistry (2010)
Inclusion Complexes of Cyclodextrins with Galangin: a Thermodynamic and Reactivity Study Jullian C.; Alfaro, M; Zapata-Torres, G; Olea Azar C. Article ISI SCOPUS Journal of Solution Chemistry (2010)
Molecular Determinants for Competitive Inhibition of alpha 4 beta 2 Nicotinic Acetylcholine Receptors Iturriaga-Vasquez, P; Carbone, A.; Garcia-Beltran, O; Livingstone, PD; Biggin, PC; Wonnacott, S; Zapata-Torres, G; Bermudez I. Article ISI SCOPUS Molecular Pharmacology (2010)
Molecular Determinants for Competitive Inhibition of alpha4beta2 Nicotinic Acetylcholine Receptors Iturriaga-Vasquez, I; Carbone, A; García-Beltran, O; Livingstone, PD; Biggin, PC; Cassels, BK; Wonnacott, S; Zapata-Torres, G; Bermudez, I Article Molecular Pharmacology (2010)
Theoretical EPR study of Nitroindazoles: 3-Alkoxy, 3-Hydroxy and 3-Oxo Derivatives Rodriguez-Becerra, J; Olea Azar C.; Zapata-Torres, G; Mendizabal, F; Gonzales, M; Cerecetto, H. Article ISI JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY (2010)
Theoretical EPR study of Nitroindazoles: 3-alkoxy, 3-hydroxy and 3-oxo derivatives Rodríguez-Becerra, J; Olea-Azar, C; Zapata-Torres, G; Mendizabal, F; González, M; Cerecetto, H. Article Journal of the Brazilian Chemical Society (2010)
Voltammetric reduction of 4-nitroimidazole derivatives: Influence of the N-1 substitution in protic and aprotic media Bollo, S; Jara-Ulloa, P; Zapata-Torres, G; Cutino, E; Sturm, JC; Nunez-Vergara, LJ; Squella, JA Article ISI SCOPUS Electrochimica Acta (2010)
Molecular modeling of the alpha 9 alpha 10 nicotinic acetylcholine receptor subtype Zapata-Torres, G Article ISI SCOPUS BIOORGANIC MEDICINAL CHEMISTRY LETTERS (2009)
Photoreduction of Oxoisoaporphines by Amines: Laser Flash and Steady-State Photolysis, Pulse Radiolysis, and TD-DFT Studies De la Fuente, JR; Aliaga C.; Poblete C.; Zapata, G; Jullian C.; Saitz C.; Cañete Á.; Kciuk, G; Sobarzo-Sanchez, E; Bobrowski K. Article ISI SCOPUS JOURNAL OF PHYSICAL CHEMISTRY A (2009)
Characterization, phase-solubility, and molecular modeling of inclusion complex of 5-nitroindazole derivative with cyclodextrins Jullian C.; Morales-Montecinos, J; Zapata-Torres, G; Aguilera B.; Rodriguez J.; Aran, V; Olea Azar C. Article ISI SCOPUS BIOORGANIC & MEDICINAL CHEMISTRY (2008)
Quantum-chemical, NMR and X-ray diffraction studies on (+/-)-1-[3,4-(methylenedioxy)phenyl]-2-methylaminopropane Zapata-Torres, G; Parra-Mouchet, J; Mascarenhas, YP; Ellena, J.; De Araujo, AS Article ISI SCOPUS JOURNAL OF MOLECULAR GRAPHICS & MODELLING (2008)
Studies of inclusion complexes of natural and modified cyclodextrin with (+)catechin by NMR and molecular modeling Jullian C.; Miranda, S.; Zapata-Torres, G; Mendizabal, F; Olea Azar C. Article ISI SCOPUS BIOORGANIC & MEDICINAL CHEMISTRY (2007)
Neurochemical and behavioural characterisation of alkoxyamphetamine derivatives in rats Bustamante, DA; Zapata-Torres, G; Goiny, M; Cassels B; Herrera-Marschitz, M Article ISI SCOPUS NEUROTOXICITY RESEARCH (2006)
A theory of protein-resin interaction in hydrophobic interaction chromatography MAHN, A; Zapata-Torres, G Article ISI SCOPUS JOURNAL OF CHROMATOGRAPHY A (2005)
Theoretical study of the interaction d(10)-s(2) between Pt(0) and Tl(I) on the [Pt(PH3)(3)Tl](+) complex Mendizabal, F; Zapata-Torres, G; Olea Azar C. Article ISI SCOPUS CHEMICAL PHYSICS LETTERS (2005)
1-Benzyl-1,2,3,4-tetrahydroisoquinolines. 1H NMR conformational studies and rotational barriers Iturriaga-Vasquez, P; Zapata-Torres, G; Cassels, B.K.; Rezende M.C. Article SCOPUS JOURNAL OF THE CHILEAN CHEMICAL SOCIETY (2004)
1-benzyl-1,2,3,4-tetrahydroisoquinolines. H-1 NMR conformational studies and rotational barriers Iturriaga-Vasquez, P; Zapata-Torres, G Article ISI JOURNAL OF THE CHILEAN CHEMICAL SOCIETY (2004)
1-BENZYL-1,2,3,4-TETRAHYDROISOQUINOLINES: ¹H NMR CONFORMATIONAL STUDIES AND ROTATIONAL BARRIERS Iturriaga-Vásquez, Patricio; Zapata-Torres, Gerald; Caroli Rezende, Marcos; Cassels, Bruce K. Article SCIELO Journal of the Chilean Chemical Society (2004)
Analgesic and behavioral effects of amphetamine enantiomers, p-methoxyamphetamine and n-alkyl-p-methoxyamphetamine derivatives Bustamante D.; Diaz-Veliz, G; Paeile, C; Zapata-Torres, G Article ISI SCOPUS PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2004)
Effects of natural flavones and flavonols on the kinase activity of Cdk5 Zapata-Torres, G; Opazo F.; Salgado, C.; Munoz, JP; Krautwurst, H; Mascayano, C; Sepulveda-Boza, S; Maccioni, RB Article ISI SCOPUS JOURNAL OF NATURAL PRODUCTS (2004)
GEOMETRICAL ISOMERISM IN ?-NITROSTYRENES: PREFERRED CONFORMATIONS OF (E)- AND (Z)- 1-(4-METHYLTHIOPHENYL)-2-NITROBUTENES HURTADO-GUZMÁN, CLAUDIO; Iturriaga-Vásquez, Patricio; Zapata-Torres, Gerald; Cassels, Bruce K. Article SCIELO Journal of the Chilean Chemical Society (2004)
Geometrical isomerism in beta-nitrostyrenes: Preferred conformations of (E)- and (Z)-1-(4-methylthiophenyl)-2-nitrobutenes Hurtado-Guzman, C; Iturriaga-Vasquez, P; Zapata-Torres, G Article ISI JOURNAL OF THE CHILEAN CHEMICAL SOCIETY (2004)
Molecular Orbital Calculations of Hydrogen Bonding in Ammonia - Formic Acid System in the Presence of Electric Fields Parra-Mouchet, JE; Zapata-Torres, G; Fink, WH; Nash, CP Article ISI SCIELO SCOPUS Journal of the Chilean Chemical Society (2004)
Probing the hydride transfer process in the lumiflavine1-methylnicotinamide model system using group softness Rivas, P; Zapata-Torres, G; Melin, J; Contreras R. Article ISI SCOPUS TETRAHEDRON (2004)
Theoretical study of the d(10)-d(8) interaction between Au(I) and Au(III) on the cis/trans-[PH3Au(I)C(L)=C(L)Au(III)(R)(2)PH3] (R = -H -CH3; L = -H, -CH3) systems Mendizabal, F; Zapata-Torres, G; Olea Azar C. Article ISI SCOPUS CHEMICAL PHYSICS LETTERS (2003)
Metallomacrocycle complex bridged polymers: electronic structures of -[MacM(L)](n) Mendizabal, F; Olea Azar C.; Zapata-Torres, G; Eisner, F Article ISI SCOPUS JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM (2001)


Crystal structure of potassium antimony hexathiodiphosphate, KSbP2S6 MAHN, A; Navarro G.; Zapata, G Abstract ISI ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES (2005)


DESIGN, SYNTHESIS AND BIOLOGICAL ASSAYS OF BIOMETAL CHELATORS, MONOAMINE OXIDASE-B AND CHOLINESTERASE INHIBITOR HYBRIDS AS MULTI-TARGET AGENTS AGAINST NEURODEGENERATIVE DISEASES. G. Zapata-Torres; Jullian, C. M. Proyecto (2017)
“beta-Cyclodextrin assisted solubilization of chromone Schiff base metal complexes to be used as a potential antitumoral target binders”. FONDECYT (1160249) Proyecto 2016-2019 Coinvestigador(a)
MOLECULAR DETERMINANTS OF AFFINITY AND EFFICACY IN SUPERPOTENT 5-HT2 RECEPTOR LIGANDS FONDECYT (1150868) Proyecto 2015-2019 Coinvestigador(a)
SUPRAMOLECULAR CHEMISTRY AT INTERFACES=>LIGHT-ABSORPTION PROCESS IN ENERGY CONVERSION AND ELECTROCATALYSIS ON GOLD ELECTRODE. A COMPUTATIONAL CHEMISTRY STUDY. FONDECYT (1140503) Proyecto 2014-2018 Coinvestigador(a)
SEARCHING FOR POSSIBLE DEPROTONATION SITES FOR SUBSTRATES AND INHIBITORS OF HUMAN MAO-A FONDECYT (1120280) Proyecto 2012-2016 Inv. Responsable
STUDY OF THE INTERACTION OF BIVALENT METALS WITH COMPLEXES OF CICLODEXTRINS-TRIAZOLOPYRIDINE DERIVATIVE AS A NEW TYPE OF CHEMOSENSOR FONDECYT (1120142) Proyecto 2012-2016 Coinvestigador(a)
HALOGEN BONDS IN DRUG DESIGN=> EXAMPLES IN THE MONOAMINERGIC AREA FONDECYT (1110146) Proyecto 2011-2015 Coinvestigador(a)
DESIGN, SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF DUAL NICOTINIC AGONIST AND MOA-B INHIBITORS ACTIVITY FOR REGULATION OF DOPAMINE LEVEL IN THE BRAIN. FONDECYT (1100542) Proyecto 2010-2014 Coinvestigador(a)
MOLECULAR MODELLING STUDIES ON THE EFFECTS OF LIGAND-BINDING SITE CONFORMATIONS ON FUNCTIONAL SELECTIVITY IN MAO-A AND 5-HT2 RECEPTORS. FONDECYT (1090215) Proyecto 2009-2012 Inv. Responsable


Targeting ? -(1,4)-Glucosidase in Diabetes Mellitus Type 2: The Role of New Synthetic Coumarins as Potent Inhibitors PeÃ±aloza-Amion M.; Veas R.; Delogu G. Review ISI SCOPUS (2018)

Fernando Mendizabal

Full Professor

Chemistry

UNIVERSIDAD DE CHILE - FACULTAD DE CIENCIAS

Santiago, Chile

Juan Squella

Académico

Química Orgánica y Físico Química

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

Maria González

Academico

FACULTAD DE MEDICINA - UNIVERSIDAD DE CHILE

Santiago, Chile

Ricardo Maccioni

DIRECTOR

RESEARCH AND DEVELOPMENT

CENTRO INTERNACIONAL DE BIOMEDICINA (ICC)

SANTIAGO, Chile

Marcela Hermoso

Full Professor

School of Medicine

UNIVERSIDAD DE CHILE

Santiago, Chile

Gerald Zapata

Profesor Asociado

Química Inorgánica y Analítica

Universidad de Chile

Santiago, Chile

SERGIO LAVANDERO

Director

Advanced Center for Chronic Diseases (ACCDiS)

UNIVERSIDAD DE CHILE, FAC CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

Mario Herrera-Marschitz

Profesor titular

Mol. & Clin. Pharmacology

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA, PROGRAMA FARMACOLOGIA MOLECULAR & CLINICA, ICBM

Santiago, Chile

SOLEDAD BOLLO

PROFESOR TITULAR

QUIMICA FARMACOLÓGICA Y TOXICOLÓGICA

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

CLAUDIO SAITZ

Associate Prof.

Organic and Phisycal Chemistry

UNIVERSIDAD DE CHILE-FAC. CS. QUIMICAS Y FARMACEUTICAS

Santiago, Chile

Julio De La Fuente

Profesor Asociado

Química Orgánica y Fisicoquímica

FAC. CS. QUÍMICAS Y FARMACÉUTICAS, UNIVERSIDAD DE CHILE

Santiago, Chile

Ziomara Gerdtzen

Profesora Asociada

Departamento de Ingeniería Química, Biotecnología y Materiales

Universidad de Chile

Santiago, Chile

ANTONIO GALDAMEZ

ASSOCIATE PROFESSOR

CHEMISTRY

DEPARTAMENTO DE QUÍMICA, FACULTAD DE CIENCIA, UNIVERSIDAD DE CHILE

SANTIAGO, Chile

Juan Maya

Full Professor

Biomedical Sciences Institute

UNIVERSIDAD DE CHILE

Santiago, Chile

ANDREA MAHN

Profesor Titular

Ingeniería Química

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

claudio olea

Full Professor

Inorganica y Analitica

UNIVERSIDAD DE CHILE

Santiago, Chile

Carlos Pessoa

Profesor Titular

Departamento de Farmacia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

CAROLINA JULLIAN

Profesor Asociado

Quimica Organica y Fisicoquimica

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

José Salgado

Associate Professor

Chemical Engineering, Biotechnology and Materials

UNIVERSIDAD DE CHILE

Santiago, Chile

Carolina Mascayano

Académico

Ciencias del Ambiente

UNIVERSIDAD DE SANTIAGO DE CHILE, FACULTAD DE QUÍMICA Y BIOLOGIA

santiago, Chile

Camilo López

prof. Asociado

Química Física

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Ramiro Arratia

DIRECTOR DOCTORADO

CIENCIAS QUIMICAS

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

Pablo Jaque

Profesor Asociado

Química Orgánica y Fisicoquímica

Universidad de Chile

Santiago, Chile

Patricio Iturriaga

Profesor Asociado A

Ciencias Quimicas y Recursos Naturales

UNIVERSIDAD DE LA FRONTERA

Temuco, Chile

Miguel Reyes

Full Professor

Facultad de Ciencias Médicas

UNIVERSIDAD DE SANTIAGO DE CHILE, FACULTAD DE CIENCIAS MÉDICAS, ESCUELA DE MEDICINA

Santiago, Chile

Carla Delporte

Profesor titular

Química Farmacológica y Toxicológica

UNIVERSIDAD DE CHILE, FACULTAD CIENCIAS QUÍMICAS Y FARMACÉUTICAS

SANTIAGO, Chile

Bruce Cassels

Profesor Titular

Departamento de Química

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS, DEPARTAMENTO DE QUÍMICA

Santiago, Chile

Ramiro Araya Maturana

Profesor Titular

Universidad de Talca

SantiaTalcago, Chile

Vicente Torres

Associate Professor

Institute for Research in Dental Sciences

FACULTAD DE ODONTOLOGÍA - UNIVERSIDAD DE CHILE

Santiago, Chile

Jorge Rodriguez

Professor

Department of Chemistry

UNIVERSIDAD METROPOLITANA DE CIENCIAS DE LA EDUCACIÓN

La Florida, Chile

Sergio Arancibia

Medical Science Liaison

Medical Affairs

Johnson & Johnson (Janssen Pharmaceutical)

Santiago, Chile

EDWIN PÉREZ

Profesor Asociado

Departamento de Química Orgánica

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

Alvaro Cañete

Profesor-investigador

instituto de ciencias químicas aplicadas

Universidad Autónoma de Chile

Santiago, Chile

Lorena Barrientos

Profesor Asistente

Pontificia Universidad Católica de Chile

Santiago, Chile

Sebastián Miranda

Profesor Asistente

Departamento de Ciencias Químicas

UNIVERSIDAD NACIONAL ANDRES BELLO

Santiago, Chile

Angelica Fierro

Associate

Chemistry

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Juan Asenjo

Professor

CHEMICAL AND BIOTECHNOLOGY ENGINEERING

University of Chile

SANTIAGO, Chile

Germán Barriga

Asociado

Quimica

Universidad Metropolitana de Ciencias de la Educación

Ñuñoa, Chile

Renato Contreras

professor

Quimica

Universidad de Chile

Santiago, Chile

Wilson Cardona

Chemistry Department Area Coordinator

Chemistry

Universidad Andrés Bello

Talcahuano, Chile

Michel Lapier

Académico

Química y Farmacia

Universidad de Valparaíso

Valparaíso, Chile

Patricio Silva

Investigador Principal FONDEF

Departamento de Biología Celular y Molecular

Universidad de Chile

Santiago, Chile

Francisco Mura

Investigador postdoctoral

Química y Biología

Universidad de Santiago de Chile

Santiago, Chile

Felipe Opazo

Group Leader

Center for Biostructural Imaging of Neuodegeneration (BIN)

Göttingen, Alemania

Gabriela Valenzuela

Profesor del Laboratorio de Productos Naturales

Química Farmacológica y Toxicológica

Universidad de Chile

Santiago, Chile

Javier Morales

Profesor Asociado

Departamento de Ciencias y Tecnología Farmacéuticas

Universidad de Chile

Santiago, Chile

JAIME MELLA

PROFESOR ADJUNTO

INSTITUTO DE QUIMICA Y BIOQUIMICA

UNIVERSIDAD DE VALPARAISO

VALPARAISO, Chile

Lucia Nuñez

ENCARGADA DE VALORACION

FACULTAD DE CIENCIAS VETERINARIAS Y PECUARIAS

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

Paul Silva

Profesor

Química Orgánica y Fisicoquímica

Universidad de Chile

Santiago, Chile

Gabriel Quiroz

Fernanda Perez

Investigadora senior principal

Síntesis orgánica

Ientropia SPA

Santiago, Chile

Iriux Almodóvar

Académico

Ciencias del Ambiente

Universidad de Santiago de Chile

Santiago, Chile

Horacio Gomez

Docente a honorarios

Química Orgánica y Fisicoquímica

Universidad de Chile

Santiago, Chile

Cinthia Quiroga

Docente a honorarios

Quimica Organica y Fisicoquimica

Universidad de Chile

Santiago, Chile

Pablo Berríos

Asistente de investigación

Universidad del Desarrollo

Santiago, Chile

Rubén Veas

Docente

Química farmacológica y toxicológica

Universidad de Chile

Santiago, Chile

Silvana Valdebenito

Assistant Professor

Neurobiology

The University of Texas Medical Branch

Galveston, Estados Unidos

Gerald Amílcar Zapata Torres

Líneas de Investigación

Educación

Química Teórica Computacional / Química Médica, UNIVERSIDAD DE CHILE. Chile, 2002

Química, UNIVERSIDAD DE CHILE. Chile, 1991

Experiencia Académica

Prof. Asociado Full Time

Experiencia Profesional

Inserción a la academia Conicyt Full Time

Premios y Distinciones

Reconocimiento de Universidad de Chile

Article (77)

Abstract (1)

Proyecto (9)

“beta-Cyclodextrin assisted solubilization of chromone Schiff base metal complexes to be used as a potential antitumoral target binders”.

MOLECULAR DETERMINANTS OF AFFINITY AND EFFICACY IN SUPERPOTENT 5-HT2 RECEPTOR LIGANDS

SUPRAMOLECULAR CHEMISTRY AT INTERFACES=>LIGHT-ABSORPTION PROCESS IN ENERGY CONVERSION AND ELECTROCATALYSIS ON GOLD ELECTRODE. A COMPUTATIONAL CHEMISTRY STUDY.

SEARCHING FOR POSSIBLE DEPROTONATION SITES FOR SUBSTRATES AND INHIBITORS OF HUMAN MAO-A

STUDY OF THE INTERACTION OF BIVALENT METALS WITH COMPLEXES OF CICLODEXTRINS-TRIAZOLOPYRIDINE DERIVATIVE AS A NEW TYPE OF CHEMOSENSOR

HALOGEN BONDS IN DRUG DESIGN=> EXAMPLES IN THE MONOAMINERGIC AREA

DESIGN, SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF DUAL NICOTINIC AGONIST AND MOA-B INHIBITORS ACTIVITY FOR REGULATION OF DOPAMINE LEVEL IN THE BRAIN.

MOLECULAR MODELLING STUDIES ON THE EFFECTS OF LIGAND-BINDING SITE CONFORMATIONS ON FUNCTIONAL SELECTIVITY IN MAO-A AND 5-HT2 RECEPTORS.

Review (1)