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Mario Herrera-Marschitz

Profesor titular

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA, PROGRAMA FARMACOLOGIA MOLECULAR & CLINICA, ICBM

Santiago, Chile

Pharmacology, Neurochemistry, Animal Models of Diseases, Perinatal Asphyxia, Addiction Biology, Treatments.

Doctor Medical Sciences, KAROLINSKA INSTITUTE. Chile, 1986
Docentship, KAROLINSKA INSTITUTE. Suecia, 1991
Physiology & Psychology, COMENIUS UNIVERSITY. Eslovaquia, 1978

Profesor titular Full Time

UNIVERSIDAD DE CHILE

Facultad de Medicina

Santiago, Chile

2001 - A la fecha
Professor Full Time

KAROLINSKA INSTITUTE

Medicine

Stockholm, Suecia

1999 - 2003
Docent Full Time

Medicine

Stockholm, Chile

1991 - 1999


Activated mesenchymal stem cell administration inhibits chronic alcohol drinking and surpesses relapse-like drinking in high drinker rats Ezquer, F; Quintanilla, ME; Morales, P; Ezquer, M; Lespay-Rebolledo, C; Herrera-Marschitz, M; Israel, Y Article ADDICTION BIOLOGY (2019)
Activation of mitochondrial aldehyde dehydrogenase (ALDH2) by ALDA-1 reduces both the acquisition and maintenance of ethanol intake in rats=> A dual mechanism? Rivera-Meza, M; Vasquez, D; Quintanilla, ME; Lagos, D; Rojas, B; Herrera-Marschitz, M; Israel, Y. Article NEUROPHARMACOLOGY (2019)
Gold nanorods/si RNA complex administration for knockdown of PARP-1=> a potential treatment for perinatal asphyxia Vio, Valentina; Riveros, Ana; Tapia-Bustos, Andrea; Lespay-Rebolledo, Carolyn; Perez-Lobos, R; Munoz, L; Pismante A, P; Morales, PR; Araya, Eyleen ; Herrera-Marschitz, M; Kogan, Marcelo J Article INTERNATIONAL JOURNAL OF NANOMEDICINE (2018)
Intranasal delivery of mesenchemycal stem cell-derived exosomes reduces oxidative stress and markedly inhibits ethanol consumption and post-deprivation relapse drinking. Ezquer, F; Quintanilla, ME; Morales, P; Santapau, D; Ezquer, M; Kogan, MJ; Salas-Huenuleo, E; Herrera-Marschitz, M; Israel, Y. Article ADDICTION BIOLOGY (2018)
Intravenous administration of anti-inflammatory mesenchymal stem cell spheroids reduces chronic alcohol intake and abolishes binge-drinking Ezquer, F; Morales, P; Quintanilla, ME; Santapau, D; Lespay-Rebolledo, C; Ezquer, M; Herrera-Marschitz, M; Israel, Y Article SCIENTIFIC REPORTS (2018)
Regionally impaired redox homeostasis in the brain of rats subjected to global perinatal asphyxia Lespay-Rebolledo, C; Perez-Lobos, R; Tapia-Bustos, A; Vio, V; Morales, P; Herrera-Marschitz, M Article NEUROTOXICITY RESEARCH (2018)
Acquisition, maintenance and relapse-like alcohol drinking=> lessons from the UChB rat line Israel, I; Karahanian, E; Ezquer, F; Morales, P; Ezquer, M; Rivera-Meza, M; Herrera-Marschitz, M; Quintanilla, ME Article Frontiers in Behavioral Neuroscience (2017)
Racemic salsolinol and it enantiomers act as agonists of the mu-opioid receptor by activating the Gi protein-adenylate cyclase pathway Berrios-Carcamos, P; Quintanilla, ME; Herrera-Marschitz, M; Vasiliou, V; Zapata-Torres, G; Rivera-Meza, M Article Frontiers in Behavioral Neuroscience (2017)
Vulnerability to a metabolic challenge following perinatal asphyxia evaluated by organotypic cultures=> effect of neonatal nicotinamide treatment Perez-Lobos, R; Lespay-Rebolledo, C; Tapia-Bustos, A; Palacio. E, Vio; V, Bustamante; D, Morles; P, Herrera-Marschitz. M Article NEUROTOXICITY RESEARCH (2017)
Vulnerability to a metabolic challenge following perinatal asphyxia evaluated by organotypic culturesL neonatal nicotinamide treatment Perez-Lobos, R; Lespay-Rebolledo, C; Tapia-Bustos, A; Palacios, E; Vio, V; Bustamante, D; Morales, P Article NEUROTOXICITY RESEARCH (2017)
Beyond the "First Hit": Marked Inhibition by N-Acetyl Cysteine of Chronic Ethanol Intake But Not of Early Ethanol Intake. Parallel Effects on Ethanol-Induced Saccharin Motivation. Israel Y, Quintanilla ME, Karahanian E, Rivera-Meza M, Herrera-Marschitz M Alcohol Clin Exp Res. 2015 May; 39(5):776-86. Article ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2016)
Long-term inhibition of ethanol intake by the administration of an aldehyde dehydrogenase-2 (ALDH2)-coding lentiviral vector into the ventral tegmental area of rats Karahanian, E; Rivera-Meza, M; Tampier, L; Quintanilla M.E.; Herrera-Marschitz, M; Israel, Y Article ISI SCOPUS ADDICTION BIOLOGY (2015)
Perinatal Asphyxia Leads to PARP-1 Overactivity, p65 Translocation, IL-1 beta and TNF-alpha Overexpression, and Apoptotic-Like Cell Death in Mesencephalon of Neonatal Rats: Prevention by Systemic Neonatal Nicotinamide Administration Neira-Pena, T; Rojas-Mancilla, E; Munoz-Vio, V; Pérez, R; Gutierrez-Hernandez, M; Bustamante D.; Morales P.; Gebicke-Haerter, P; Herrera-Marschitz, M Article ISI SCOPUS Neurotoxicity Research (2015)
Gene expression in superior temporal cortex of schizophrenia patients Sellmann, C; Pildain, LV; Schmitt, A; Leonardi-Essmann, F; Durrenberger, PF; Spanagel, R; Arzberger, T; Kretzschmar, H; Zink, M; Gruber, O; et al. Article ISI SCOPUS EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE (2014)
Overexpression of Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels into the Ventral Tegmental Area Increases the Rewarding Effects of Ethanol in UChB Drinking Rats Rivera-Meza, M; Bustamante D.; Delgado, R; Buscaglia M.; Herrera-Marschitz, M Article ISI SCOPUS ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2014)
Salsolinol, free of isosalsolinol, exerts ethanol-like motivational/sensitization effects leading to increases in ethanol intake Rivera-Meza, M; Berrios-Cárcamo, PA; Bustamante D.; Buscaglia M.; Morales P.; Karahanian, E; Herrera-Marschitz, M; Israel, Y Article ISI SCOPUS ALCOHOL (2014)
Additive effect of rimonabant and citalopram on extracellular serotonin levels monitored with in vivo microdialysis in rat brain Ortega, J.E; Gonzalez-Lira, V; Horrillo, I; Herrera-Marschitz, M; Callado, LF; Meana, JJ Article ISI SCOPUS European Journal of Pharmacology (2013)
The Alcohol Deprivation Effect: Marked Inhibition by Anticatalase Gene Administration into the Ventral Tegmental Area in Rats Tampier, L; Karahanian, E; Rivera-Meza, M; Herrera-Marschitz, M; Israel, Y Article ISI SCOPUS Alcoholism: Clinical and Experimental Research (2013)
Further Studies on the Hypothesis of PARP-1 Inhibition as a Strategy for Lessening the Long-Term Effects Produced by Perinatal Asphyxia: Effects of Nicotinamide and Theophylline on PARP-1 Activity in Brain and Peripheral Tissue Allende-Castro C.; Espina-Marchant, P; Bustamante D.; Rojas-Mancilla, E; Neira, T; Esmar D.; Valdes, J. L.; Morales P.; Herrera-Marschitz, M Article ISI SCOPUS Neurotoxicity Research (2012)
Reward and Relapse: Complete Gene-Induced Dissociation in an Animal Model of Alcohol Dependence Quintanilla M.E.; Tampier, L; Karahanian, E; Rivera-Meza, M; Herrera-Marschitz, M; Israel, Y Article ISI SCOPUS Alcoholism: Clinical and Experimental Research (2012)
Structural synaptic elements are differentially regulated in superior temporal cortex of schizophrenia patients Schmitt, A; Leonardi-Essmann, F; Wichert S.P.; Spanagel, R; Arzberger, T; Kretzschmar, H; Zink, M; Herrera-Marschitz, M; Reynolds, R; Rossner M.J.; et al. Article ISI SCOPUS European Archives of Psychiatry and Clinical Neuroscience (2012)
Ethanol as a Prodrug: Brain Metabolism of Ethanol Mediates its Reinforcing Effects Karahanian, E; Tampier, L; Rivera-Meza, M; Bustamante D.; Gonzalez-Lira, V; Morales P.; Herrera-Marschitz, M; Israel, Y Article ISI SCOPUS Alcoholism: Clinical and Experimental Research (2011)
Perinatal asphyxia: current status and approaches towards neuroprotective strategies, with focus on sentinel proteins Herrera-Marschitz, M; Morales P.; Leyton, L; Bustamante D.; Klawitter, V; Espina-Marchant, P; Allende, C.; Lisboa F.; Cunich G.; Jara-Cavieres A.; et al. Article ISI SCOPUS Neurotoxicity Research (2011)
Regulation of immune-modulatory genes in left superior temporal cortex of schizophrenia patients: a genome-wide microarray study Schmitt, A; Leonardi-Essmann, F; Durrenberger, PF; Parlapani E.; Schneider-Axmann T.; Spanagel, R; Arzberger, T; Kretzschmar, H; Herrera-Marschitz, M; Gruber, O; et al. Article ISI SCOPUS World Journal of Biological Psychiatry (2011)
The hypoxic rat model for obstetric complications in schizophrenia Schmitt, A; Falkai, P; Gebicke-Haerter, P; Sommer, U; Heck M.; Zink, M; Lex, A; Fendt, M; Herrera-Marschitz, M Article SCOPUS Neuromethods (2011)
Differential expression of presynaptic genes in a rat model of postnatal hypoxia: relevance to schizophrenia Sommer, JU; Schmitt, A; Heck M.; Schaeffer, EL; Fendt, M; Zink, M; Nieselt K.; Symons, S; Petroianu, G; Lex, A; et al. Article ISI SCOPUS European Archives of Psychiatry and Clinical Neuroscience (2010)
Nicotinamide prevents the long-term effects of perinatal asphyxia on apoptosis, non-spatial working memory and anxiety in rats Morales P.; Simola, N; Bustamante D.; Lisboa F.; Fiedler J.; Gebicke-Haerter, PJ; Morelli, M; Tasker, RA; Herrera-Marschitz, M Article ISI SCOPUS Experimental Brain Research (2010)
The rotational model and microdialysis: Significance for dopamine signalling, clinical studies, and beyond Herrera-Marschitz, M; Arbuthnott, G; Ungerstedt, U Article ISI SCOPUS Progress in Neurobiology (2010)
Rat strain influences the use of egocentric learning strategies mediated by neostriatum Espina-Marchant, P; Pinto-Hamuy, T; Bustamante D.; Morales P.; Herrera-Marschitz, M Article ISI SCOPUS EXPERIMENTAL BRAIN RESEARCH (2009)
Acute perinatal asphyxia impairs non-spatial memory and alters motor coordination in adult male rats Simola, N; Bustamante D.; Pinna, A; Pontis, S; Morales P.; Morelli, M; Herrera-Marschitz, M Article ISI SCOPUS EXPERIMENTAL BRAIN RESEARCH (2008)
Ethanol induces stronger dopamine release in nucleus accumbens (shell) of alcohol-preferring (bibulous) than in alcohol-avoiding (abstainer) rats Bustamante D.; Tampier, L; Gonzalez-Lira, V; Israel, Y; Herrera-Marschitz, M Article ISI SCOPUS EUROPEAN JOURNAL OF PHARMACOLOGY (2008)
Dopamine release in the nucleus accumbens (shell) of two lines of rats selectively bred to prefer or avoid ethanol Bustamante D.; Tampier, L; Israel, Y; Herrera-Marschitz, M Article ISI SCOPUS EUROPEAN JOURNAL OF PHARMACOLOGY (2007)
Exploring neurocircuitries of the basal ganglia by intracerebral administration of selective neurotoxins Herrera-Marschitz, M; Bustamante D.; Morales P.; Goiny, M Article ISI SCOPUS NEUROTOXICITY RESEARCH (2007)
Nicotinamide prevents the effect of perinatal asphyxia on dopamine release evaluated with in vivo microdialysis 3 months after birth Bustamante D.; Morales P.; Pereyra, JT; Goiny, M; Herrera-Marschitz, M Article ISI SCOPUS EXPERIMENTAL BRAIN RESEARCH (2007)
Perinatal asphyxia induces neurogenesis in hippocampus: an organotypic culture study Morales P.; Huaiquin, P; Bustamante D.; Fiedler J.; Herrera-Marschitz, M Article ISI SCOPUS NEUROTOXICITY RESEARCH (2007)
Plasticity of basal ganglia neurocircuitries following perinatal asphyxia: effect of nicotinamide Klawitter, V; Morales P.; Bustamante D.; Gomez-Urquijo, S; Hokfelt, T; Herrera-Marschitz, M Article ISI SCOPUS EXPERIMENTAL BRAIN RESEARCH (2007)
Neurochemical and behavioural characterisation of alkoxyamphetamine derivatives in rats Bustamante, DA; Zapata-Torres, G; Goiny, M; Cassels B; Herrera-Marschitz, M Article ISI SCOPUS NEUROTOXICITY RESEARCH (2006)
Plasticity of the central nervous system (CNS) following perinatal asphyxia: Does nicotinamide provide neuroprotection? Klawitter, V; Morales P.; Bustamante D.; Goiny, M; Herrera-Marschitz, M Article ISI SCOPUS AMINO ACIDS (2006)
Spatial cognition and memory: A reversible lesion lidocaine into the anteromedial/posterior parietal cortex (AM/PPC) affects differently working and long-term memory on two foraging tasks Espina-Marchant, P; Pinto-Hamuy, T; Robles, L; Bustamante D.; Morales P.; Herrera-Marschitz, M Article SCOPUS BIOLOGICAL RESEARCH (2006)
Spatial cognition and memory: a reversible lesion with lidocaine into the anteromedial/posterior parietal cortex (AM/PPC) affects differently working and long-term memory on two foraging tasks Espina-Marchant, P; Pinto-Hamuy, T; Bustamante D.; Morales P.; Robles, L; Herrera-Marschitz, M Article ISI SCIELO BIOLOGICAL RESEARCH (2006)
Effect of perinatal asphyxia on tyrosine hydroxylase and D2 and D1 dopamine receptor mRNA levels expressed during early postnatal development in rat brain Gross, J; Andersson, K.; Chen, Y; Muller, I; Andreeva, N; Herrera-Marschitz, M Article ISI SCOPUS MOLECULAR BRAIN RESEARCH (2005)
Effects of perinatal asphyxia on cell proliferation and neuronal phenotype evaluated with organotypic hippocampal cultures Morales P.; Reyes, P.; Klawitter, V; Huaiquin, P; Bustamante D.; Fiedler J.; Herrera-Marschitz, M Article ISI SCOPUS NEUROSCIENCE (2005)
Effects of perinatal asphyxia on cell survival, neuronal phenotype and neurite growth evaluated with organotypic triple cultures Klawitter, V; Morales P.; Johansson, S; Bustamante D.; Goiny, M; Gross, J; Luthman, J; Herrera-Marschitz, M Article ISI SCOPUS AMINO ACIDS (2005)
Modulation of ventral pallidal dopamine and glutamate release by the intravenous anesthetic propofol studied by in vivo microdialysis Grasshoff, C; Herrera-Marschitz, M; Goiny, M; Kretschmer, BD Article ISI SCOPUS AMINO ACIDS (2005)
Effects of the DT-diaphorase inhibitor dicumarol on striatal monoamine levels in L-DOPA and L-deprenyl pre-treated rats Bustamante D.; Bustamante L.; Segura-Aguilar, J; Goiny, M; Herrera-Marschitz, M Article ISI NEUROTOXICITY RESEARCH (2004)
Nicotinamide prevents the long-term effects of perinatal asphyxia on basal ganglia monoamine systems in the rat Bustamante D.; Goiny, M; Astrom, G; Gross, J; Andersson, K.; Herrera-Marschitz, M Article ISI SCOPUS EXPERIMENTAL BRAIN RESEARCH (2003)
Perinatal asphyxia impairs connectivity and dopamine neurite branching in organotypic triple culture from rat substantia nigra, neostriatum and neocortex Morales P.; Klawitter, V; Johansson, S; Huaiquin, P; Barros, VG; Avalos, AM; Fiedler J.; Bustamante D.; Gomez-Urquijo, S; Goiny, M; et al. Article ISI SCOPUS NEUROSCIENCE LETTERS (2003)
Corticosterone differentially regulates bax, bcl-2 and bcl-x mRNA levels in the rat hippocampus Cardenas sp; Parra, C; Bravo, J; Morales P.; Herrera-Marschitz, M Article ISI SCOPUS NEUROSCIENCE LETTERS (2002)
Effect of single and repeated methamphetamine treatment on neurotransmitter release in substantia nigra and neostriatum of the rat Bustamante D.; You, ZB; Castel, MN; Johansson, S; Goiny, M; Terenius, L; Hokfelt, T; Herrera-Marschitz, M Article ISI JOURNAL OF NEUROCHEMISTRY (2002)
Inhibition of DT-diaphorase is a requirement for Mn3+ to produce a 6-OH-dopamine like rotational behaviour Segura-Aguilar, J; Diaz-Veliz, G; Mora S.; Herrera-Marschitz, M Article SCOPUS NEUROTOXICITY RESEARCH (2002)
Comparison between hypothermia and glutamate antagonism treatments on the immediate outcome of perinatal asphyxia Engidawork, E; Loidl, F; Chen, Y; Kohlhauser, C; Stoeckler, S; Dell'Anna, E; Lubec, B; Lubec, G; Goiny, M; Gross, J; et al. Article ISI SCOPUS EXPERIMENTAL BRAIN RESEARCH (2001)


AN ANTICATALASE LENTIVIRAL VECTOR REDUCED ETHANOL INTAKE IN DEVELOPMENTALLY-LEAD-EXPOSED RATS Mattalloni, MS; Salinas, C; Herrera-Marschitz, M; Israel, Y; Cancela, LM; Rivera-Meza, M; Virgolini, MB Abstract ISI ALCOHOL AND ALCOHOLISM (2015)
SALSOLINOL, AN ALCOHOL-DERIVED METABOLITE, ACTS AS AN AGONIST OF THE MU-OPIOID RECEPTOR Rivera-Meza, M; Berrios-Carcamo, P; Herrera-Marschitz, M Abstract ISI ALCOHOL AND ALCOHOLISM (2015)
A CLEAR PARADOX: AVERSIVE EFFECTS OF LIVER-GENERATED ACETALDEHYDE BUT REWARDING/REINFORCING EFFECTS OF ACETALDEHYDE GENERATED IN THE BRAIN Israel, Y; Karahanian, E; Rivera-Meza, M; Herrera-Marschitz, M Abstract ISI ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2014)
KNOCKDOWN OF HCN CHANNELS INTO THE VENTRAL TEGMENTAL AREA REDUCES ETHANOL CONSUMPTION IN UCHB DRINKING RATS Rivera-Meza, M; Morales P.; Herrera-Marschitz, M Abstract ISI ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2014)
SALSOLINOL, FREE OF ISOSALSOLINOL, EXERTS ETHANOL- LIKE MOTIVATIONAL/SENSITIZATION EFFECTS LEADING TO INCREASES IN ETHANOL INTAKE Rivera-Meza, M; Berrios-Carcamo, P; Bustamante D.; Buscaglia M.; Morales P.; Karahanian, E; Herrera-Marschitz, M; Israel, Y Abstract ISI ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2014)
OVEREXPRESSION OF HCN CHANNELS INTO THE VENTRAL TEGMENTAL AREA INCREASES THE REWARDING EFFECTS OF ETHANOL Rivera-Meza, M; Tampier, L; Herrera-Marschitz, M Abstract ISI ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2013)
COMBINED INHIBITION OF REWARD AND CONDITIONING PREVENTS RELAPSE IN AN ANIMAL MODEL OF ALCOHOL DEPENDENCE Karahanian, E; Tampier, L; Rivera-Meza, M; Herrera-Marschitz, M; Israel, Y Abstract ISI ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2012)
DIFFERENTIAL EXPRESSION OF STRUCTURAL SYNAPTIC ELEMENTS IN THE LEFT SUPERIOR TEMPORAL CORTEX OF SCHIZOPHRENIA PATIENTS Schmitt, A; Falkai, PG; Leonardi-Essmann, F; Durrenberger, PF; Gruber, O; Arzberger, T; Kretzschmar, H; Herrera-Marschitz, M; Reynolds, R; Gebicke-Harter, P Abstract ISI SCHIZOPHRENIA BULLETIN (2011)
MICROINJECTION OF AN ANTI-CATALASE SHRNA-CODING LENTIVIRAL VECTOR INTO BRAIN VENTRAL TEGMENTAL AREA (VTA) VIRTUALLY ABOLISHES ETHANOL INTAKE BY RATS BRED AS HIGH ALCOHOL DRINKERS Karahanian, E; Tampier, L; Bustamante D.; Gonzalez-Lira, V; Morales P.; Herrera-Marschitz, M; Israel, Y Abstract ISI ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2010)
ROLE OF ACETALDEHYDE ON THE MOTIVATIONAL PROPERTIES OF ETHANOL IN RATS BRED AS HEAVY DRINKERS Gonzalez-Lira, V; Bustamante D.; Tampier, L; Israel, Y; Herrera-Marschitz, M Abstract ISI ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2010)
Acute and long-term neuronal loss induced by perinatal asphyxia: activation of pro-apoptotic, anti-apoptotic and sentinel proteins Morales P.; Bustamante D.; Lisboa F.; Allende, C.; Espina-Marchant, P; Gutierrez, M; Jara, A; Gonzalez-Lira, V; Simola, N; Morelli, M; et al. Abstract ISI AMINO ACIDS (2009)
Predictive diagnostics of long-term outcomes in perinatal asphyxia Peeva V.; Yeghiazaryan K.; Herrera-Marschitz, M; Golubnitschaja O. Abstract ISI AMINO ACIDS (2009)
Effect of poly(ADP-ribose) polymerase-1 (PARP-1) inhibition on metabolic insults occurring at birth: promises and limitations Morales P.; Salech, F; Katunar, M; Canovas, J.; Klawitter, V; Bustamante D, D; Kukuljan M.; Antonelli, M; couve, a; Herrera-Marschitz, M Abstract ISI AMINO ACIDS (2007)


On postnatal CNS plasticity Herrera-Marschitz, M EditorialMaterial ISI AMINO ACIDS (2006)
General introduction: Neurobiology at the 8(th) International Congress on Amino Acids and Proteins, Rome, Italy, September 2003 Herrera-Marschitz, M; Kretschmer, BD; Kostrzewa, RM EditorialMaterial ISI SCOPUS AMINO ACIDS (2005)
Introduction: Vulnerability of the CNS to metabolic and drug-related insults (Chapter 1) Kretschmer, BD; Kostrzewa, RM; Herrera-Marschitz, M EditorialMaterial ISI SCOPUS AMINO ACIDS (2005)
Transport proteins: targets for glutamate pharmacology? Herrera-Marschitz, M EditorialMaterial ISI AMINO ACIDS (2004)
Amino acids in neurobiology: Neuroprotective and neurotoxic aspects of amino acids involved in neurotransmission and neuromodulation - General Introduction Kretschmer, BD; Schmidt, WJ; Kostrzewa, RM; Herrera-Marschitz, M EditorialMaterial ISI AMINO ACIDS (2002)


Mesenchymal stem cells-secretome provides protection in neonatal hypoxia-deoxygenation. Mechanisms and translational studies FONIS (1190562) Proyecto 2019-2022 Coinvestigador(a)
The oxidative stress-neuroinflammation synergy=> role in the perpetuation of alcohol intake and therapeutic avenues. FONDECYT (1180042) Proyecto 2018-2020 Coinvestigador(a)
REWARDING MOLECULES GENERATED FROM ETHANOL IN THE BRAIN FONDECYT (1130012) Proyecto 2013-2016 Coinvestigador(a)
ASPHYXIA AT BIRTH PRIMES CNS DEVELOPMENT AND INCREASES THE VULNERABILITY TO SUBSEQUENT POSTNATAL INSULTS FONDECYT (1120079) Proyecto 2012-2016 Inv. Responsable
MODULATION OF NEUROGENESIS BY PERINATAL ASPHYXIA=> ROLE OF DOPAMINE AND REGULATORS OF G-PROTEINS (RGS) FONDECYT (1110263) Proyecto 2011-2015 Coinvestigador(a)
GENE SILENCING OF HCN CHANNELS AND ITS EFFECTS ON THE STIMULATING AND REWARDING EFFECTS OF ETHANOL FONDECYT (3110107) Proyecto 2010-2013 Inv. Patrocinante
Millennium Institute in Bioneuroscience. Millenium Initiative, Ministerio de Economia, Chile (BNI P09-015-F) Proyecto 2010-2016 Coinvestigador(a)
ETHANOL AS A PRODRUG FONDECYT (1095021) Proyecto 2009-2013 Coinvestigador(a)
LONG-TERM CHANGES IN BRAIN NEUROCIRCUITRIES PRODUCED BY PERINATAL ASPHYXIA=> IS POLY(ADP-RIBOSE) POLYMERASE-1 (PARP-1) INHIBITION A STRATEGY FOR NEUROPROTECTION? FONDECYT (1080447) Proyecto 2008-2012 Inv. Responsable
PLASTICITY OF THE CENTRAL NERVOUS SYSTEM=> EFFECTS OF PERINATAL ASPHYXIA AND METABOLIC INSULTS FONDECYT (1030521) Proyecto 2003-2006 Inv. Responsable
Neurocircuitry of the basal ganglia studied with in vivo and in vitro models=> effects of intracerebral and perinatal asphyctic lesions Swedish Medical Research Coucil (K2001-04X-08669-13B) Proyecto 2001-2004 Inv. Principal
NEUROCIRCUITRY OF THE BASAL GANGLIA STUDIED WITH IN VIVO AND IN VITRO MODELS=> EFFECTS OF METABOLIC AND INTRACEREBRAL LESIONS FONDECYT (1000626) Proyecto 2000-2003 Inv. Responsable


The "First Hit" Toward Alcohol Reinforcement: Role of Ethanol Metabolites Israel, Y; Karahanian, E; Rivera-Meza, M; Herrera-Marschitz, M Review ISI SCOPUS Alcoholism: Clinical and Experimental Research (2015)
Perinatal asphyxia: CNS development and deficits with delayed onset Herrera-Marschitz, M; Neira-Pena, T; Rojas-Mancilla, E; Espina-Marchant, P; Esmar D.; Pérez, R; Muñoz, V.; Gutierrez-Hernandez, M; Rivera, B; Simola, N; et al. Review ISI SCOPUS FRONTIERS IN NEUROSCIENCE (2014)
Gene specific modifications unravel ethanol and acetaldehyde actions Israel, Y; Rivera-Meza, M; Karahanian, E; Tampier, L; Morales P.; Herrera-Marschitz, M Review ISI SCOPUS Frontiers in Behavioral Neuroscience (2013)
Plasticity of hippocampus following perinatal asphyxia: Effects on postnatal apoptosis and neurogenesis Morales P.; Andres S; Berríos C.; Huaiquin, P; Bustamante D.; Cárdenas, S.; Parra, E; Herrera-Marschitz, M Review ISI SCOPUS JOURNAL OF NEUROSCIENCE RESEARCH (2008)

Marcela Hermoso

Full Professor

School of Medicine

UNIVERSIDAD DE CHILE

Santiago, Chile

Gerald Zapata

Profesor Asociado

Química Inorgánica y Analítica

Universidad de Chile

Santiago, Chile

Mario Herrera-Marschitz

Profesor titular

Mol. & Clin. Pharmacology

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA, PROGRAMA FARMACOLOGIA MOLECULAR & CLINICA, ICBM

Santiago, Chile

Paola Morales

Profesor Asociado

Programa Farmacología Molecular & Clínica, ICBM,

Universidad de Chile

Santiago, Chile

JENNY FIEDLER

LAB. NEUROPLASTICIDAD Y NEUROGENETICA. DEPTO BIOQUIMICA Y BIOLOGÍA MOLECULAR. FAC. CIENCIAS QUÍMICAS Y FARMACÉUTICAS. UNIVERSIDAD DE CHILE

Santiago, Chile

Ricardo Delgado

Profesor Adjunto

Biología

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS, DEPARTAMENTO DE BIOLOGIA

Santiago, Chile

Andrés Couve

Profesor Titular

Neurociencia

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

Eduardo Karahanian

Académico Investigador

Facultad de Ciencias de la Salud

Universidad Autónoma de Chile

Santiago, Chile

Bruce Cassels

Profesor Titular

Departamento de Química

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS, DEPARTAMENTO DE QUÍMICA

Santiago, Chile

Lisette Leyton

Full Professor

Núcleo Interdisciplinario Biología y Genética

FACULTAD DE MEDICINA UNIVERSIDAD DE CHILE

Santiago, Chile

José Valdés

Profesor Asociado

Neurociencia

UNIVERSIDAD DE CHILE

Santiago, Chile

María Quintanilla

PROFESOR ASOCIADO

FARMACOLOGÍA MOLECULAR Y CLÍNICA

UNIVERSIDAD DE CHILE, FACULLTAD DE MEDICINA, INSTITUTO DE CIENCIAS BIOMÉDICAS, PROGRAMA DE FARMACOLOGÍA MOLECULAR Y CLÍNICA

Santiago, Chile

Yedy Israel

Profesor Titular

Farmacologia Molecular y Clinica

UNIVERSIDAD DE CHILE, FACULTAD DE CS QUIMICAS Y FARMACÉUTICAS, LAB. FARMACOTERAPIA GÉNICA

Santiago, Chile

JAVIER BRAVO

PROFESOR ADJUNTO

INSTITUTO DE QUÍMICA

PONTIFICIA UNIVERSIDAD CATÓLICA DE VALPARAISO

VALPARAÍSO, Chile

Eduardo Parra

ACADÉMICO - ESCUELA DE MEDICINA

MEDICINA

UNIVERSIDAD DE TARAPACA

Arica, Chile

Eduardo Karahanian

Professor

INSTITUTO DE CIENCIAS BIOMEDICAS

UNIVERSIDAD AUTONOMA DE CHILE

Santiago, Chile

Felipe Salech

Academic

Medicine

Universidad de Chile / Facultad de Medicina

Santiago, Chile

Sergio Cárdenas

Coordinador de Investigación e investigador

Centro de Ingeniería y desarrollo sostenible

Universidad Central de Chile

Santiago, Chile

Edgardo Rojas

Académico e Investigador

Ciencias Químicas y Biológicas

Universidad Bernardo OHiggins

Santiago, Chile

Marianne Buscaglia

Estudiante de Doctorado en Ciencias Biológicas, mención Genética Molecular y Microbiología

Genética Molecular y Microbiología

Pontificia Universidad Católica de Chile

Santiago, Chile

Pablo Berríos

Asistente de investigación

Universidad del Desarrollo

Santiago, Chile

Camilo Allende

Docente

Universidad del Desarrollo

Santiago, Chile

Mario Herrera-Marschitz

Líneas de Investigación

Educación

Doctor Medical Sciences, KAROLINSKA INSTITUTE. Chile, 1986

Docentship, KAROLINSKA INSTITUTE. Suecia, 1991

Physiology & Psychology, COMENIUS UNIVERSITY. Eslovaquia, 1978

Experiencia Académica

Profesor titular Full Time

Professor Full Time

Docent Full Time

Article (51)

Abstract (13)

EditorialMaterial (5)

Proyecto (12)

Mesenchymal stem cells-secretome provides protection in neonatal hypoxia-deoxygenation. Mechanisms and translational studies

The oxidative stress-neuroinflammation synergy=> role in the perpetuation of alcohol intake and therapeutic avenues.

REWARDING MOLECULES GENERATED FROM ETHANOL IN THE BRAIN

ASPHYXIA AT BIRTH PRIMES CNS DEVELOPMENT AND INCREASES THE VULNERABILITY TO SUBSEQUENT POSTNATAL INSULTS

MODULATION OF NEUROGENESIS BY PERINATAL ASPHYXIA=> ROLE OF DOPAMINE AND REGULATORS OF G-PROTEINS (RGS)

GENE SILENCING OF HCN CHANNELS AND ITS EFFECTS ON THE STIMULATING AND REWARDING EFFECTS OF ETHANOL

Millennium Institute in Bioneuroscience.

ETHANOL AS A PRODRUG

LONG-TERM CHANGES IN BRAIN NEUROCIRCUITRIES PRODUCED BY PERINATAL ASPHYXIA=> IS POLY(ADP-RIBOSE) POLYMERASE-1 (PARP-1) INHIBITION A STRATEGY FOR NEUROPROTECTION?

PLASTICITY OF THE CENTRAL NERVOUS SYSTEM=> EFFECTS OF PERINATAL ASPHYXIA AND METABOLIC INSULTS

Neurocircuitry of the basal ganglia studied with in vivo and in vitro models=> effects of intracerebral and perinatal asphyctic lesions

NEUROCIRCUITRY OF THE BASAL GANGLIA STUDIED WITH IN VIVO AND IN VITRO MODELS=> EFFECTS OF METABOLIC AND INTRACEREBRAL LESIONS

Review (4)