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jose luis valdes guerrero

Profesor Asociado

UNIVERSIDAD DE CHILE

Santiago, Chile

Líneas de Investigación


APRENDIZAJE y MEMORIA; ALERTA Y MOTIVACION; SISTEMAS NEUROMODULADORES;

Educación

  •  Ciencias Biomedicas, UNIVERSIDAD DE CHILE. Chile, 2005
  •  Biologia, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1999

Experiencia Académica

  •   Profesor Asistente Full Time

    UNIVERSIDAD DE CHILE

    Medicina

    Santiago, Chile

    2009 - 2017

  •   Profesor Asociado Full Time

    UNIVERSIDAD DE CHILE

    Medicina

    Santiago, Chile

    2017 - A la fecha

Experiencia Profesional

  •   Postdoctorado Full Time

    Pontificia UNiversidad Catolica de Chile

    Santiago, Chile

    2005 - 2006

  •   Postdoctorado Full Time

    University of Arizona

    Tucosn, Estados Unidos

    2007 - 2008

  •   Profesor Asociado Full Time

    Universidad de Chile

    Santiago, Chile

    2009 - A la fecha

Formación de Capital Humano


Magister en Neurociencias (Universidad de Chile)
Jessica Sanchez. Graduada (19 de Marzo 2018); Rodrigo Cisneros. Graduado (9 de mayo 2017); Stephanie Cortez. Graduada (28 de agosto 2017); Javier Silva. Graduado (6 de Junio 2017); Marcos Domic. Graduado (16 de Junio de 2017); Noemí Grinspun. Graduada (Junio del 2013); Juan Pablo Osorio. Graduado (Octubre del 2012); Gonzalo Bustamante. Graduado (Julio del 2016); Mauricio Toro. Graduado (Enero del 2015).; Jamileth More. Graduada (Septiembre del 2015).

Magister en Bioquimica (Universidad de Chile
Juan Galindo. Graduado (April del 2016).

Doctorado en Ciencias Biomédicas (Universidad de Chile)
Ingrid Buller. Graduada (Marzo del 2017); Noemi Grinspun. Graduada (25 septiembre, 2017); Yerko Fuentealba. Graduado (15 Marzo, 2018).

Doctorado en Ciencias Medicas (Universidad de Chile)
NIcole Rogers Graduada (10 de enero, 2019)

Postdoc
Marcos Contreras (2010-2012)
Margarita Borquez (2017-2018)



 

Article (25)

Differential navigational strategies during spatial learning in a new modified version of the Oasis maze
c-Fos expression in the ascending arousal system induced by physical exercise in rats: Implication for memory performance
Effort Displayed During Appetitive Phase of Feeding Behavior Requires Infralimbic Cortex Activity and Histamine H1 Receptor Signaling
Timing Is of the Essence: Improvement in Perception During Active Sensing
Calcium Release Mediated by Redox-Sensitive RyR2 Channels Has a Central Role in Hippocampal Structural Plasticity and Spatial Memory
Long-lasting, reversible and non-neurotoxic inactivation of hippocampus activity induced by neosaxitoxin
N-Acetylcysteine Prevents the Spatial Memory Deficits and the Redox-Dependent RyR2 Decrease Displayed by an Alzheimer's Disease Rat Model
Triclosan Impairs Hippocampal Synaptic Plasticity and Spatial Memory in Male Rats
Asynchronous ripple oscillations between left and right hippocampi during slow-wave sleep
Local Klotho enhances neuronal progenitor proliferation in the adult hippocampus
Targeting Sentinel Proteins and Extrasynaptic Glutamate Receptors=> a Therapeutic Strategy for Preventing the Effects Elicited by Perinatal Asphyxia?
Effect of perinatal asphyxia on tuberomammillary nucleus neuronal density and object recognition memory=> A possible role for histamine?
Regulation of Memory Formation by the Transcription Factor XBP1
The Histaminergic Tuberomamillary Nucleus Is Involved in Appetite for Sex, Water and Amphetamine
Lack of phonotactic preferences of female frogs and its consequences for signal evolution.
Off-Line Reactivation of Experience-Dependent Neuronal Firing Patterns in the Rat Ventral Tegmental Area.
Further Studies on the Hypothesis of PARP-1 Inhibition as a Strategy for Lessening the Long-Term Effects Produced by Perinatal Asphyxia: Effects of Nicotinamide and Theophylline on PARP-1 Activity in Brain and Peripheral Tissue
Histamine and motivation.
The histaminergic tuberomammillary nucleus is critical for motivated arousal.
The parietal association cortex of the rat.
La corteza prefrontal medial controla el alerta conductual y vegetativo. Implicancias en desórdenes de la conducta.
The infralimbic cortical area commands the behavioral and vegetative arousal during appetitive behavior in the rat.
Arousal and differential Fos expression in histaminergic neurons of the ascending arousal system during a feeding-related motivated behaviour.
Differential effects of infralimbic cortical lesions on temperature and locomotor activity responses to feeding in rats.
Specific activation of histaminergic neurons during daily feeding anticipatory behavior in rats.

BookSection (1)

Molecular, cellular and behavioural effects produced by perinatal asphyxia: protection by poly(ADP-ribose) polymerase 1 (PARP-1) inhibition

Proyecto (9)

Apoyo a la formación de Redes Internacionales entre centros de Investigación
Mesenchymal stem cells-secretome provides protection in neonatal hypoxia-reoxygenation. Mechanisms and translational studies
Test de navegación virtual detecta de forma rápida y precisa el deterioro cognitivo inicial en personas mayores
The precise timing of motor modulations as a mechanism for active sensing in the visual system
Biomedical Neuroscience Institute
Center for Neuroscience of Memory, (CENEM),
High order perception of needs and emotions
Role of hippocampal histaminergic activity during acquisition and consolidation of memory
Defective Calcium/Redox signaling and anomalous elctrical brain activity in rats injected with amyloid beta oligomers: Functional and behavioural correlates with alzheimer's patients
21
jose valdes

Profesor Asociado

Neurociencia

UNIVERSIDAD DE CHILE

Santiago, Chile

4
Jamileth More

Investigador

Neurologia

Hospital Clinico Universidad de Chile

Santiago, Chile

3
Andrea Paula-Lima

Assistant Professor

Institute for research in Dental Sciences

Universidad de Chile

Santiago, Chile

3
Gina Sanchez

Profesor Asociado

ICBM

UNIVERSIDAD DE CHILE, FAC MEDICINA , ICBM

Santiago, Chile

2
M. Cecilia Hidalgo

Professor

ICBM

Universidad de Chile

Santiago, Chile

2
Tatiana Adasme

Associate Researcher

Centro de Investigación Clínica Avanzada (CICA)

Universidad Chile

Santiago, Chile

2
Pedro Maldonado

Profesor Titular

Departamento de Neurociencias

FACULTAD DE MEDICINA. U. DE CHILE

Santiago, Chile

2
Andrea Paula-Lima

Profesora Asociada

Instituto de Investigación en Ciencias Odontológicas

UNIVERSIDAD DE CHILE

Santiago, Chile

2
Genaro Barrientos

Profesor Asistente

Fisiologia y Biofisica, ICBM

UNIVERSIDAD DE CHILE

Santiago, Chile

1
ALEXIS HUMERES

DIRECTOR

MORFOFUNCIÓN

Universidad Diego Portales

SANTIAGO, Chile

1
José Galaz

Estudiante de Posgrado

Instituto de Investigación en Ciencias Odontológicas

Universidad de Chile

Santiago, Chile

1
Edgardo Rojas

Académico e Investigador

Ciencias Químicas y Biológicas

Universidad Bernardo OHiggins

Santiago, Chile

1
Barbara Bruna

Asistente de Investigación

Hospital Clinico universidad de Chile-Universidad de Chile

Santiago, Chile

1
Mario Herrera-Marschitz

Profesor titular

Mol. & Clin. Pharmacology

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA, PROGRAMA FARMACOLOGIA MOLECULAR & CLINICA, ICBM

Santiago, Chile

1
Paola Morales

Profesor Asociado

Programa Farmacología Molecular & Clínica, ICBM,

Universidad de Chile

Santiago, Chile