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jose luis valdes guerrero

Profesor Asociado

UNIVERSIDAD DE CHILE

Santiago, Chile

APRENDIZAJE y MEMORIA; ALERTA Y MOTIVACION; SISTEMAS NEUROMODULADORES;

Ciencias Biomedicas, UNIVERSIDAD DE CHILE. Chile, 2005
Biologia, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1999

Profesor Asistente Full Time

UNIVERSIDAD DE CHILE

Medicina

Santiago, Chile

2009 - 2017
Profesor Asociado Full Time

UNIVERSIDAD DE CHILE

Medicina

Santiago, Chile

2017 - A la fecha

Postdoctorado Full Time

Pontificia UNiversidad Catolica de Chile

Santiago, Chile

2005 - 2006
Postdoctorado Full Time

University of Arizona

Tucosn, Estados Unidos

2007 - 2008
Profesor Asociado Full Time

Universidad de Chile

Santiago, Chile

2009 - A la fecha

Magister en Neurociencias (Universidad de Chile)
Jessica Sanchez. Graduada (19 de Marzo 2018); Rodrigo Cisneros. Graduado (9 de mayo 2017); Stephanie Cortez. Graduada (28 de agosto 2017); Javier Silva. Graduado (6 de Junio 2017); Marcos Domic. Graduado (16 de Junio de 2017); Noemí Grinspun. Graduada (Junio del 2013); Juan Pablo Osorio. Graduado (Octubre del 2012); Gonzalo Bustamante. Graduado (Julio del 2016); Mauricio Toro. Graduado (Enero del 2015).; Jamileth More. Graduada (Septiembre del 2015).

Magister en Bioquimica (Universidad de Chile
Juan Galindo. Graduado (April del 2016).

Doctorado en Ciencias Biomédicas (Universidad de Chile)
Ingrid Buller. Graduada (Marzo del 2017); Noemi Grinspun. Graduada (25 septiembre, 2017); Yerko Fuentealba. Graduado (15 Marzo, 2018).

Doctorado en Ciencias Medicas (Universidad de Chile)
NIcole Rogers Graduada (10 de enero, 2019)

Postdoc
Marcos Contreras (2010-2012)
Margarita Borquez (2017-2018)


Differential navigational strategies during spatial learning in a new modified version of the Oasis maze Concha-Miranda, Miguel; More, Jamileth; Grinspun, Noemi; Sanchez, Cristian; Paula-Lima, Andrea; Valdés, José L. Article ISI SCOPUS Behavioural Brain Research (2020)
c-Fos expression in the ascending arousal system induced by physical exercise in rats: Implication for memory performance Grinspun N.; Fuentealba Y.; Falcon R.; ValdÃ©s J.L. Article ISI SCOPUS BRAIN RESEARCH (2019)
Effort Displayed During Appetitive Phase of Feeding Behavior Requires Infralimbic Cortex Activity and Histamine H1 Receptor Signaling Riveros M.E.; Forray M.I.; Torrealba F.; ValdÃ©s J.L. Article ISI SCOPUS FRONTIERS IN NEUROSCIENCE (2019)
Timing Is of the Essence: Improvement in Perception During Active Sensing Concha-Miranda, Miguel; Rios, Javier; Bu, Joaquin; Valdes, Jose Luis; Maldonado, Pedro E Article ISI SCOPUS FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2019)
Calcium Release Mediated by Redox-Sensitive RyR2 Channels Has a Central Role in Hippocampal Structural Plasticity and Spatial Memory More, Jamileth Y.; Bruna, Barbara A.; Lobos, Pedro E.; Galaz, José L.; Figueroa, Paula L.; Namias, Silvia; Sánchez, Gina L.; Barrientos, Genaro C.; Valdés, José L.; Paula-Lima, Andrea C.; Hidalgo, Cecilia; Adasme, Tatiana Article ISI SCOPUS ANTIOXIDANTS & REDOX SIGNALING (2018)
Long-lasting, reversible and non-neurotoxic inactivation of hippocampus activity induced by neosaxitoxin Galindo, J.; Contreras, M.; Maldonado, P.; Torrealba, F.; Lagos, N.; Valdes, J. L. Article ISI SCOPUS JOURNAL OF NEUROSCIENCE METHODS (2018)
N-Acetylcysteine Prevents the Spatial Memory Deficits and the Redox-Dependent RyR2 Decrease Displayed by an Alzheimer's Disease Rat Model More, Jamileth; Galusso, Nadia; Veloso, Pablo; Montecinos, Luis; Pablo Finkelstein, Jose; Sanchez, Gina; Bull, Ricardo; Luis Valdes, Jose; Hidalgo, Cecilia; Paula-Lima, Andrea Article ISI FRONTIERS IN AGING NEUROSCIENCE (2018)
Triclosan Impairs Hippocampal Synaptic Plasticity and Spatial Memory in Male Rats Arias-Cavieres, Alejandra; More, Jamileth; Miguel Vicente, Jose; Adasme ,Tatiana; Hidalgo, Jorge; Luis Valdes, Jose; Humeres, Alexis; Valdes-Undurraga, Ismael; Sanchez, Gina; Hidalgo, Cecilia; Barrientos, Genaro Article ISI SCOPUS FRONTIERS IN MOLECULAR NEUROSCIENCE (2018)
Asynchronous ripple oscillations between left and right hippocampi during slow-wave sleep Villalobos Claudio, Maldonado Pedro Article PLoS One (2017)
Local Klotho enhances neuronal progenitor proliferation in the adult hippocampus Salech Felipe Couve A.; Varela-Nallar, Lorena; Arredondo, Sebastian B.; Bustamante, Daniel B.; Andaur, Gabriela; Cisneros, Rodrigo; Ponce, Daniela; Inestrosa, Nibaldo C.; Valdes, Jose L; Beherens, Maria I.; Couve, Andres Article ISI J Gerontol A Biol Sci Med Sci. (2017)
Targeting Sentinel Proteins and Extrasynaptic Glutamate Receptors=> a Therapeutic Strategy for Preventing the Effects Elicited by Perinatal Asphyxia? Herrera-Marschitz, M; Perez-Lobos, R; Lespay-Rebolledo, C; Tapia-Bustos, A; Casanova-Ortiz, E; Morales, P; Valdes, JL; Bustamante, D; Cassels, BK Article NEUROTOXICITY RESEARCH (2017)
Effect of perinatal asphyxia on tuberomammillary nucleus neuronal density and object recognition memory=> A possible role for histamine? Flores-Balter, Gabriela; Cordova-Jadue, Hector; Chiti-Morales, Alessandra; Lespay Caroline, Espina-Marchant Pablo; Falcon Romina, Grinspun; Noemi, Sanchez Jessica; Bustamante, Diego; Morales, Paola; Herrera-Marschitz, Mario Article BEHAVIOURAL BRAIN RESEARCH (2016)
Regulation of Memory Formation by the Transcription Factor XBP1 Martínez, Gabriela; Vidal, Rene; Mardones, Pablo; Serrano, Felipe; Ardiles, Alvaro; Wirth, Craigh; Valdés, Pamela; Thielen, Peter; Schneider, Bernard; Kerr, Bredford; Valdés, Jose Luis; Palacios, Adrian; Inestrosa, Nibaldo; Glimcher, Laurie; Hetz, Claudio. Article Cell Reports (2016)
The Histaminergic Tuberomamillary Nucleus Is Involved in Appetite for Sex, Water and Amphetamine Contreras, Marco; Riveros, Maria; Quispe, Maricel; Sánchez, Cristian; Perdomo, Guayec; Torrealba, Fernando; Valdés, Jose Luis. Article PLoS One (2016)
Lack of phonotactic preferences of female frogs and its consequences for signal evolution. Velásquez, Nelson A; Valdés, Jose Luis; Vásquez, Rodrigo A; Penna, Mario Article Behavioural processes (2015)
Off-Line Reactivation of Experience-Dependent Neuronal Firing Patterns in the Rat Ventral Tegmental Area. Valdes, Jose L; McNaughton, Bruce L; Fellous, Jean-Marc Article Journal of neurophysiology (2015)
Further Studies on the Hypothesis of PARP-1 Inhibition as a Strategy for Lessening the Long-Term Effects Produced by Perinatal Asphyxia: Effects of Nicotinamide and Theophylline on PARP-1 Activity in Brain and Peripheral Tissue Allende-Castro C.; Espina-Marchant, P; Bustamante D.; Rojas-Mancilla, E; Neira, T; Gutierrez-Hernandez M.A.; Esmar D.; Valdes, J. L.; Morales P.; Gebicke?Haerter, P.J.; Herrera-Marschitz, M Article ISI SCOPUS Neurotoxicity Research (2012)
Histamine and motivation. Torrealba, Fernando; Riveros, Maria E; Contreras, Marco; Valdes, Jose L Article Frontiers in systems neuroscience (2012)
The histaminergic tuberomammillary nucleus is critical for motivated arousal. Valdés, José Luis; Sánchez, Cristián; Riveros, María Eugenia; Blandina, Patrizio; Contreras, Marco; Farías, Paula; Torrealba, Fernando Article The European journal of neuroscience (2010)
The parietal association cortex of the rat. Torrealba, Fernando; Valdés, José Luis Article Biological research (2008)
La corteza prefrontal medial controla el alerta conductual y vegetativo. Implicancias en desórdenes de la conducta. Valdes J.L.; Torrealba F. Article Rev Chil Neuro-Psiquiat (2006)
The infralimbic cortical area commands the behavioral and vegetative arousal during appetitive behavior in the rat. Valdés, José Luis; Maldonado, Pedro; Recabarren, Mónica; Fuentes, Rómulo; Torrealba, Fernando Article The European journal of neuroscience (2006)
Arousal and differential Fos expression in histaminergic neurons of the ascending arousal system during a feeding-related motivated behaviour. Valdés, J L; Farías, P; Ocampo-Garcés, A; Cortés, N; Serón-Ferré, M; Torrealba, F Article The European journal of neuroscience (2005)
Differential effects of infralimbic cortical lesions on temperature and locomotor activity responses to feeding in rats. Recabarren, M P; Valdés, J L; Farías, P; Serón-Ferré, M; Torrealba, F Article Neuroscience (2005)
Specific activation of histaminergic neurons during daily feeding anticipatory behavior in rats. Meynard, Margarita M; Valdés, José Luis; Recabarren, Mónica; Serón-Ferré, María; Torrealba, Fernando Article Behavioural brain research (2005)


Molecular, cellular and behavioural effects produced by perinatal asphyxia: protection by poly(ADP-ribose) polymerase 1 (PARP-1) inhibition Neira, T; Espina-Marchant, P; Rojas-Mancilla, E; Esmar D.; Munoz, V; Perez, R; Rivera B.; Bustamante, D; Valdes, JL; Hermoso, M; Gebicke-Haerter, P; Morales, P; Herrera-Marschitz, M; Kostrzewa, R.M. BookSection (2014)


Apoyo a la formación de Redes Internacionales entre centros de Investigación Henny, P; Valdes, JL; Acuña-Goycolea, C Proyecto (2019)
Mesenchymal stem cells-secretome provides protection in neonatal hypoxia-reoxygenation. Mechanisms and translational studies Morales, P; Valdes, JL; Herrera-MArrshitz, M; Israel, Y; Quintanilla, ME; Ezquer, F Proyecto (2019)
Test de navegación virtual detecta de forma rápida y precisa el deterioro cognitivo inicial en personas mayores Behrens, María Isabel; Valdés, José L. Proyecto (2019)
The precise timing of motor modulations as a mechanism for active sensing in the visual system Maldonado, P; Valdes, JL Proyecto (2019)
Biomedical Neuroscience Institute couve, a; Valdes, JL Proyecto (2011)
Center for Neuroscience of Memory, (CENEM), Aboitiz, F; Valdes, JL; Maldonado, P; Fuentealba, P Proyecto (2010)
High order perception of needs and emotions Torrealba, Fernando; Valdes, JL Proyecto (2010)
Role of hippocampal histaminergic activity during acquisition and consolidation of memory Valdes, Jose L Proyecto (2009)
Defective Calcium/Redox signaling and anomalous elctrical brain activity in rats injected with amyloid beta oligomers: Functional and behavioural correlates with alzheimer's patients Paula-Lima, A; Valdes, JL; Maldonado,P; Behrens, MI; Hidalgo, MC Proyecto (0)