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Profesora Asociada

UNIVERSIDAD DE CHILE

Santiago, Chile

Neurobiology of Alzheimer´s disease; Endoplasmic reticulum, Mitochondria & Neuronal Calcium Signaling; Neuroinflammation.

Biotechnologist, Federal Institute of Chemistry of Rio de Janeiro. Brasil, 1996
Pharmacist, Federal University of Rio de Janeiro. Brasil, 2003
PhD in Biological Chemistry, Federal University of Rio de Janeiro. Chile, 2007
University teaching, UNIVERSIDAD DE CHILE. Chile, 2012
Post Doctorate , UNIVERSIDAD DE CHILE. Chile, 2011

Assistant Professor Full Time

UNIVERSIDAD DE CHILE

Faculty of Medicine

Santiago, Chile

2010 - 2011
Associate Professor Full Time

UNIVERSIDAD DE CHILE

Faculty of Dentistry

Santiago, Chile

2011 - A la fecha
Associate Professor Part Time

UNIVERSIDAD DE CHILE

Faculty of Medicine

Santiago, Chile

2019 - A la fecha
Coordinadora de Postgrado Full Time

UNIVERSIDAD DE CHILE

Faculty of Dentistry

Santiago, Chile

2013 - 2018

Técnica de Laboratorio de Bacteriología Clínica Full Time

Fiocruz

Rio de Janeiro, Brasil

1996 - 1996
Asistente de Docencia en Laboratorio Part Time

Instituto Federal de Química do Rio de Janeiro

Rio de Janeiro, Chile

1995 - 1995


Astaxanthin Counteracts Excitotoxicity and Reduces the Associated Increases in Calcium Levels and Mitochondrial Reactive Oxygen Species Generation Cataldo K.; Estay C.; Paula Lima A.; Munoz P.C. Article ISI SCOPUS Marine Drugs (2020)
Differential navigational strategies during spatial learning in a new modified version of the Oasis maze Sanchez, Cristian Article ISI SCOPUS BEHAVIOURAL BRAIN RESEARCH (2020)
Redox modifications in synaptic components as biomarkers of cognitive status, in brain aging and disease Munoz P.C.; Pérez-Espinosa B.; Epinosa-Parrilla Y. Article ISI Mechanisms of Ageing and Development (2020)
Calcium Release Mediated by Redox-Sensitive RyR2 Channels Has a Central Role in Hippocampal Structural Plasticity and Spatial Memory More, Jamileth Y.; Lobos, Pedro E.; Galaz, José L.; Figueroa, Paula L.; Namias, Silvia Article ISI SCOPUS ANTIOXIDANTS & REDOX SIGNALING (2018)
Reactive oxygen species released from astrocytes treated with amyloid beta oligomers elicit neuronal calcium signals that decrease phospho-Ser727-STAT3 nuclear content Article ISI SCOPUS FREE RADICAL BIOLOGY AND MEDICINE (2018)
The signaling pathways underlying BDNF-induced Nrf2 hippocampal nuclear translocation involve ROS, RyR-Mediated Ca2+ signals, ERK and PI3K Hidalgo, Cecilia; Adasme ,Tatiana Article ISI SCOPUS BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)


Role of RyR2-mediated calcium release in synaptic plasticity, learning and memory in control and AD-model rats Hidalgo C.; More J.; Valdes, I; San-Martin, C; Munoz P.; Barrientos G.; Valdés, JL; Sanchez G.; Paula Lima A. Abstract ISI JOURNAL OF NEUROCHEMISTRY (2015)


El serotipo b Aggregatibacter actinomycetemcomitans es parte del consorcio de bacterias periodontales que participan en la etiología de la enfermedad de Alzheimer Andrea Paula-Lima Proyecto (2020)