
Gina Luisa Sanchez Vergara
Profesor Asociado
UNIVERSIDAD DE CHILE, FAC MEDICINA , ICBM
Santiago, Chile
Redox regulation of proteins, intracellular calcium concentration, signal transduction, cell death, apoptosis, autophagy. Molecular mechanism of cardioprotection, Ischemia Reperfusion cardiac, mechanism of degradation of proteins, mitochondrial dynam
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Bioquimico, UNIVERSIDAD DE CHILE. Chile, 2008
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Academico Full Time
UNIVERSIDAD DE CHILE
Medicina
Santiago, Chile
1999 - A la fecha
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Académico Full Time
Universidad de Chile
Santiago, Chile
2008 - A la fecha
2005-2007
Student: Agustin Alvarado Osorio
Title: "Phosphorylation of Sarcoplasmic Reticulum Proteins by Preconditioning Tachycardia.",
Institution: UNIVERSIDAD DE CHILE, Master / Master / DEA
2008-2010
Student: Ernesto Muñoz
Title: "Activity of the Sarcoplasmic Reticulum Reticulum Calcium Pump and its Redox Modifications",
Institution: UNIVERSIDAD DE CHILE, Master
2008-2009
Student: Carolina Fernández Pérez
Title: "Participation of mitochondrial permeability transition pore (mPTP) in preconditioning by tachycardia",
Institution: UNIVERSIDAD DE CHILE, Master
2009-2012
Student: Mauricio Ibacache
Title: "Cardioprotection by dexmedetomedine in myocardial ischemia and reperfusion",
Institution: UNIVERSIDAD DE CHILE, PhD
2009-2010
Student: Julio Miranda Betancourt
Title: "S-glutathionylation of the ryanodine receptor in skeletal muscle of insulin-resistant mice.",
Institution: UNIVERSIDAD DE CHILE, Master
2012-2014
Student: Javier Pezoa
Title: "Degradation of RyR2 in rat hearts subjected to ischemia-reperfusion: role of calpains and proteosome",
Institution: UNIVERSIDAD DE CHILE, Master
2013-2017
Student: Quezada Catalán, Mauricio
Title: "Effect of ascorbic acid on the damage caused by reperfusion in an isolated heart infarct model of a rat",
Institution: UNIVERSIDAD DE CHILE, Master
2013-2015
Student: Jaime Riquelme
Title: "Role of the eNOS-nitric oxide-cGMP-dependent protein kinase pathway in the preconditioning cardiac effect of dexmedetomidine",
Institution: UNIVERSIDAD DE CHILE, PhD
2015-2016
Student: CHALMERS ESPINOZA, STEFANIE GRACE
Title: "Cardioprotective effect of n-acetylcysteine in the damage produced by ischemia, on the content of mitofusin 2, in isolated heart of rat",
Institution: UNIVERSIDAD DE CHILE, Master
2015-2017
Student: BERRIOS ZAMORA, DANIELA
Title: "Effect of the Proteasome Chymotrypsin Activity on the damage produced by ischemia in rat isolated heart",
Institution: UNIVERSIDAD ARTURO PRAT, Bachelor
2015-2018
Student: González, Jaime
Title: "Pharmacological prevention of myocardial damage due to reperfusion in acute myocardial infarction",
Institution: UNIVERSIDAD DE CHILE, PhD
2016-2017
Student: Conejeros Vasquez Carolina
Title: "Participation of Miro1 in hypertrophy in neonatal rat cardiomyocytes",
Institution: UNIVERSIDAD DE CHILE, Master
2016-2017
Student: Ahumada Cortes Xavier
Title: "Effect of the inhibition of the chymotrypsin activity of the proteasome during ischemia, in the mitochondrial structure of the rat isolated heart",
Institution: UNIVERSIDAD DE CHILE, Master
2016-2018
Student: Huechamil Iglesias Matias Ignacio
Title: " The use of iron chelators decreases diastolic dysfunction in an ex vivo model of ischemia and reperfusion due to the inhibition of titin redox status ",
Institution: UNIVERSIDAD DE CHILE, Master
2017-2018
Student: Inostroza Herrera Cristopher
Title: "Decreased myocardial damage by reperfusion in the Langendorff model by co-administration of Ascorbic Acid and Deferoxamine",
Institution: UNIVERSIDAD DE CHILE, Master
2017-2019
Student: Utreras Mendoza Yildy
Title: "" Identification of the signaling pathway of cardiac hypertrophy in C57BL / 6J mice fed a high-fat diet "",
Institution: UNIVERSIDAD DE CHILE, PhD
2018-2019
Student: Mujica Isidora
Title: "Effect of obesity produced by a high-fat diet on the cellular redox balance in the heart",
Institution: UNIVERSIDAD DE CHILE, Master
2017- 2019
Student: Gajardo, Abraham Isaac Jacob
Title: "Effect of" autonomic stress "on cardioprotection due to remote ischemic preconditioning: transferring ischemic conditioning from the laboratory to clinical practice",
Institution: UNIVERSIDAD DE CHILE, PhD
Patent of Invention
INAPI
registry number 56881
Headline: Universidad de Chile
Inventors:
Sánchez Vergara, Gina; Prieto Domínguez, Juan Carlos; Florenzano Urzúa, Fernando; Gormaz Araya, Juan Guillermo; Rodrigo Salinas, Ramón; Aguayo Nayle, Rubén.
Title:
Pharmaceutical injectable antioxidant composition comprising high dose ascorbic acid, N-acetyl cysteine ??and deferoxamine; use in the prevention of damage by perfusion in patients before, during and after angioplasty, acute myocardial infarction or reperfusion in cerebrovascular accident.
Application 2014-3326
Date of application: 05-12-2014
Award date: 04-10-2018
Date of granting registration number: 03-01-2019
Effective date: 05-12-2014
Expiry date: 05-12-2034
Posttranslational Modifications of Cardiac Ryanodine Receptors/Calcium Release Channels by ROS and RNS. En: Systems Biology of Free Radicals and Anti-Oxidants |
Posttranslational modifications of cardiac ryanodine receptors/calcium release channels by reactive oxygen species and reactive nitrogen species |
Non ischemic myocardial preconditioning by tachycardia and exercise |
Infarto perioperatorio en cirugía no-cardíaca y dexmedetomidina |

SERGIO LAVANDERO
Director
Advanced Center for Chronic Diseases (ACCDiS)
UNIVERSIDAD DE CHILE, FAC CIENCIAS QUÍMICAS Y FARMACÉUTICAS
Santiago, Chile

Mario Chiong
Profesor
Departamento de Bioquímica y Biología Molecular
Universidad de Chile
Santiago, Chile

Marcelo Kogan
Academico
Quimica Farmacologica y Toxicologica
UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS QUÍMICAS Y FARMACÉUTICAS
Santiago, Chile

Andrew Quest
Full Professor
Biologia Celular y Molecular
FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE
Santiago, Chile

Jorge Llanos
PROFESOR TITULAR
FISIOPATOLOGÍA
UNIVERSIDAD DE CHILE - FACULTAD DE MEDICINA
Santiago, Chile

Ramón Rodrigo
PROFESOR TITULAR
INSTITUTO DE CIENCIAS BIOMÉDICAS
UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA, INSTITUTO DE CIENCIAS BIOMÉDICAS, PROGRAMA DE FARMACOLOGÍA MOLECULAR Y CLÍNICA
Santiago, Chile

Lorena Garcia
Assistant Professor
Bioquimica y Biologia Molecular
UNIVERSIDAD DE CHILE
Santiago, Chile

Tatiana Adasme
Coordinadora de Estudios
Oficina de Apoyo a la Investigación Clínica
Universidad Chile
Santiago, Chile

Paola Llanos
Profesor Asistente
Instituto de Investigacion en Ciencias Biomédicas
FACULTAD DE ODONTOLOGIA. UNIVERSIDAD DE CHILE
Santiago, Chile

Clara Quiroga
Profesor Asistente Adjunto
División de Enfermedades Cardiovasculares
Pontificia Universidad Católica de Chile
Santiago, Chile

Andrea Paula-Lima
Profesora Asociada
Instituto de Investigación en Ciencias Odontológicas
UNIVERSIDAD DE CHILE
Santiago, Chile

Genaro Barrientos
Profesor Asistente
Fisiologia y Biofisica, ICBM
UNIVERSIDAD DE CHILE
Santiago, Chile

Jaime Riquelme
Assistant Professor
Química Farmacológica y Toxicológica
Universidad de Chile
Santiago, Chile

Maria Behrens
Profesor Titular
Neurología y Neurocirugía, y de Neurociencia
Hospital Clínico Universidad de Chile
Santiago, Chile

Andrea Paula-Lima
Assistant Professor
Institute for research in Dental Sciences
Universidad de Chile
Santiago, Chile

PAOLA HAEGER
Associated professor
Ciencias Biomedicas
Universidad Catolica del Norte
COQUIMBO, Chile

Valentina Parra
Profesora Asistente / Assistant Professor
Departamento de Bioquímica y Biología Molecular
UNIVERSIDAD DE CHILE
Santiago, Chile

Pablo Aránguiz
Jefe de Carrera
Escuela de Ciencias de la Salud
Universidad Vina del Mar
Viña del Mar, Chile

Erwin de la Fuente
PROFESOR ASOCIADO
CIENCIAS BIOMÉDICAS
UNIVERSIDAD CATOLICA DEL NORTE
Coquimbo, Chile

Maria Ocaranza
Full Professor
Cardiovascular Diseases Division
Pontificia Universidad Catolica de Chile
Santiago, Chile

Rodrigo Troncoso
Associate Professor
Instituto de Nutrición y Tecnología de los Alimentos
Santiago, Chile

Zully Pedrozo
Associated Professor
Physiology and Biophysical
Universidad de Chile
SANTIAGO DE CHILE, Chile

Veronica Eisner
Associate Professor
Cellular and Molecular Biology
Pontificia Universidad Católica de Chile
Santiago, Chile

José Galaz
Estudiante de Posgrado
Instituto de Investigación en Ciencias Odontológicas
Universidad de Chile
Santiago, Chile

Barbara Bruna
Postdoctoral Researcher
Hospital Clinico universidad de Chile-Universidad de Chile
Santiago, Chile

Matias Escobar
Postdoctoral Researcher
Cancer Biology
University of Pennsylvania
Philadelphia, Chile

Victor Parra
Médico titular
ICBM, Facultad de Medicina
Instituto Nacional del Tórax y Universidad de Chile
Santiago, Chile

Andrea Ramírez
Asistente de Investigación
Bioquímica
Universidad de Chile
Región Metropolitana, Chile